diff --git a/.changeset/afraid-carpets-try.md b/.changeset/afraid-carpets-try.md
new file mode 100644
index 0000000..b723f3d
--- /dev/null
+++ b/.changeset/afraid-carpets-try.md
@@ -0,0 +1,5 @@
+---
+'@apollo/datasource-rest': minor
+---
+
+If your provided `cache` is created with `PrefixingKeyValueCache.cacheDangerouslyDoesNotNeedPrefixesForIsolation` (new in `@apollo/utils.keyvaluecache@2.1.0`), the `httpcache:` prefix will not be added to cache keys.
diff --git a/package-lock.json b/package-lock.json
index 00fe97a..cf269e2 100644
--- a/package-lock.json
+++ b/package-lock.json
@@ -10,7 +10,7 @@
       "license": "MIT",
       "dependencies": {
         "@apollo/utils.fetcher": "^2.0.0",
-        "@apollo/utils.keyvaluecache": "^1.0.2",
+        "@apollo/utils.keyvaluecache": "^2.0.0",
         "@types/http-cache-semantics": "^4.0.1",
         "http-cache-semantics": "^4.1.0",
         "lodash.isplainobject": "^4.0.6",
@@ -118,59 +118,6 @@
         "graphql": "14.x || 15.x || 16.x"
       }
     },
-    "node_modules/@apollo/server-gateway-interface/node_modules/@apollo/utils.keyvaluecache": {
-      "version": "2.0.1",
-      "resolved": "https://registry.npmjs.org/@apollo/utils.keyvaluecache/-/utils.keyvaluecache-2.0.1.tgz",
-      "integrity": "sha512-F1v3m2pMXPD3rb2+F79qklBBFtNSWssV+8YJIAI0iLxRxoNdDAzfrBFUseUaBaeen/e5mR54QkeNCiq8EvQ/Eg==",
-      "dev": true,
-      "dependencies": {
-        "@apollo/utils.logger": "^2.0.0",
-        "lru-cache": "^7.14.1"
-      },
-      "engines": {
-        "node": ">=14"
-      }
-    },
-    "node_modules/@apollo/server-gateway-interface/node_modules/@apollo/utils.logger": {
-      "version": "2.0.0",
-      "resolved": "https://registry.npmjs.org/@apollo/utils.logger/-/utils.logger-2.0.0.tgz",
-      "integrity": "sha512-o8qYwgV2sYg+PcGKIfwAZaZsQOTEfV8q3mH7Pw8GB/I/Uh2L9iaHdpiKuR++j7oe1K87lFm0z/JAezMOR9CGhg==",
-      "dev": true,
-      "engines": {
-        "node": ">=14"
-      }
-    },
-    "node_modules/@apollo/server-gateway-interface/node_modules/lru-cache": {
-      "version": "7.14.1",
-      "resolved": "https://registry.npmjs.org/lru-cache/-/lru-cache-7.14.1.tgz",
-      "integrity": "sha512-ysxwsnTKdAx96aTRdhDOCQfDgbHnt8SK0KY8SEjO0wHinhWOFTESbjVCMPbU1uGXg/ch4lifqx0wfjOawU2+WA==",
-      "dev": true,
-      "engines": {
-        "node": ">=12"
-      }
-    },
-    "node_modules/@apollo/server/node_modules/@apollo/utils.keyvaluecache": {
-      "version": "2.0.1",
-      "resolved": "https://registry.npmjs.org/@apollo/utils.keyvaluecache/-/utils.keyvaluecache-2.0.1.tgz",
-      "integrity": "sha512-F1v3m2pMXPD3rb2+F79qklBBFtNSWssV+8YJIAI0iLxRxoNdDAzfrBFUseUaBaeen/e5mR54QkeNCiq8EvQ/Eg==",
-      "dev": true,
-      "dependencies": {
-        "@apollo/utils.logger": "^2.0.0",
-        "lru-cache": "^7.14.1"
-      },
-      "engines": {
-        "node": ">=14"
-      }
-    },
-    "node_modules/@apollo/server/node_modules/@apollo/utils.logger": {
-      "version": "2.0.0",
-      "resolved": "https://registry.npmjs.org/@apollo/utils.logger/-/utils.logger-2.0.0.tgz",
-      "integrity": "sha512-o8qYwgV2sYg+PcGKIfwAZaZsQOTEfV8q3mH7Pw8GB/I/Uh2L9iaHdpiKuR++j7oe1K87lFm0z/JAezMOR9CGhg==",
-      "dev": true,
-      "engines": {
-        "node": ">=14"
-      }
-    },
     "node_modules/@apollo/server/node_modules/lru-cache": {
       "version": "7.14.1",
       "resolved": "https://registry.npmjs.org/lru-cache/-/lru-cache-7.14.1.tgz",
@@ -273,26 +220,32 @@
       }
     },
     "node_modules/@apollo/utils.keyvaluecache": {
-      "version": "1.0.2",
-      "resolved": "https://registry.npmjs.org/@apollo/utils.keyvaluecache/-/utils.keyvaluecache-1.0.2.tgz",
-      "integrity": "sha512-p7PVdLPMnPzmXSQVEsy27cYEjVON+SH/Wb7COyW3rQN8+wJgT1nv9jZouYtztWW8ZgTkii5T6tC9qfoDREd4mg==",
+      "version": "2.1.0",
+      "resolved": "https://registry.npmjs.org/@apollo/utils.keyvaluecache/-/utils.keyvaluecache-2.1.0.tgz",
+      "integrity": "sha512-WBNI4H1dGX2fHMk5j4cJo7mlXWn1X6DYCxQ50IvmI7Xv7Y4QKiA5EwbLOCITh9OIZQrVX7L0ASBSgTt6jYx/cg==",
       "dependencies": {
-        "@apollo/utils.logger": "^1.0.0",
-        "lru-cache": "7.10.1 - 7.13.1"
+        "@apollo/utils.logger": "^2.0.0",
+        "lru-cache": "^7.14.1"
+      },
+      "engines": {
+        "node": ">=14"
       }
     },
     "node_modules/@apollo/utils.keyvaluecache/node_modules/lru-cache": {
-      "version": "7.13.1",
-      "resolved": "https://registry.npmjs.org/lru-cache/-/lru-cache-7.13.1.tgz",
-      "integrity": "sha512-CHqbAq7NFlW3RSnoWXLJBxCWaZVBrfa9UEHId2M3AW8iEBurbqduNexEUCGc3SHc6iCYXNJCDi903LajSVAEPQ==",
+      "version": "7.14.1",
+      "resolved": "https://registry.npmjs.org/lru-cache/-/lru-cache-7.14.1.tgz",
+      "integrity": "sha512-ysxwsnTKdAx96aTRdhDOCQfDgbHnt8SK0KY8SEjO0wHinhWOFTESbjVCMPbU1uGXg/ch4lifqx0wfjOawU2+WA==",
       "engines": {
         "node": ">=12"
       }
     },
     "node_modules/@apollo/utils.logger": {
-      "version": "1.0.0",
-      "resolved": "https://registry.npmjs.org/@apollo/utils.logger/-/utils.logger-1.0.0.tgz",
-      "integrity": "sha512-dx9XrjyisD2pOa+KsB5RcDbWIAdgC91gJfeyLCgy0ctJMjQe7yZK5kdWaWlaOoCeX0z6YI9iYlg7vMPyMpQF3Q=="
+      "version": "2.0.0",
+      "resolved": "https://registry.npmjs.org/@apollo/utils.logger/-/utils.logger-2.0.0.tgz",
+      "integrity": "sha512-o8qYwgV2sYg+PcGKIfwAZaZsQOTEfV8q3mH7Pw8GB/I/Uh2L9iaHdpiKuR++j7oe1K87lFm0z/JAezMOR9CGhg==",
+      "engines": {
+        "node": ">=14"
+      }
     },
     "node_modules/@apollo/utils.printwithreducedwhitespace": {
       "version": "2.0.0",
@@ -10066,22 +10019,6 @@
         "whatwg-mimetype": "^3.0.0"
       },
       "dependencies": {
-        "@apollo/utils.keyvaluecache": {
-          "version": "2.0.1",
-          "resolved": "https://registry.npmjs.org/@apollo/utils.keyvaluecache/-/utils.keyvaluecache-2.0.1.tgz",
-          "integrity": "sha512-F1v3m2pMXPD3rb2+F79qklBBFtNSWssV+8YJIAI0iLxRxoNdDAzfrBFUseUaBaeen/e5mR54QkeNCiq8EvQ/Eg==",
-          "dev": true,
-          "requires": {
-            "@apollo/utils.logger": "^2.0.0",
-            "lru-cache": "^7.14.1"
-          }
-        },
-        "@apollo/utils.logger": {
-          "version": "2.0.0",
-          "resolved": "https://registry.npmjs.org/@apollo/utils.logger/-/utils.logger-2.0.0.tgz",
-          "integrity": "sha512-o8qYwgV2sYg+PcGKIfwAZaZsQOTEfV8q3mH7Pw8GB/I/Uh2L9iaHdpiKuR++j7oe1K87lFm0z/JAezMOR9CGhg==",
-          "dev": true
-        },
         "lru-cache": {
           "version": "7.14.1",
           "resolved": "https://registry.npmjs.org/lru-cache/-/lru-cache-7.14.1.tgz",
@@ -10106,30 +10043,6 @@
         "@apollo/utils.fetcher": "^2.0.0",
         "@apollo/utils.keyvaluecache": "^2.0.1",
         "@apollo/utils.logger": "^2.0.0"
-      },
-      "dependencies": {
-        "@apollo/utils.keyvaluecache": {
-          "version": "2.0.1",
-          "resolved": "https://registry.npmjs.org/@apollo/utils.keyvaluecache/-/utils.keyvaluecache-2.0.1.tgz",
-          "integrity": "sha512-F1v3m2pMXPD3rb2+F79qklBBFtNSWssV+8YJIAI0iLxRxoNdDAzfrBFUseUaBaeen/e5mR54QkeNCiq8EvQ/Eg==",
-          "dev": true,
-          "requires": {
-            "@apollo/utils.logger": "^2.0.0",
-            "lru-cache": "^7.14.1"
-          }
-        },
-        "@apollo/utils.logger": {
-          "version": "2.0.0",
-          "resolved": "https://registry.npmjs.org/@apollo/utils.logger/-/utils.logger-2.0.0.tgz",
-          "integrity": "sha512-o8qYwgV2sYg+PcGKIfwAZaZsQOTEfV8q3mH7Pw8GB/I/Uh2L9iaHdpiKuR++j7oe1K87lFm0z/JAezMOR9CGhg==",
-          "dev": true
-        },
-        "lru-cache": {
-          "version": "7.14.1",
-          "resolved": "https://registry.npmjs.org/lru-cache/-/lru-cache-7.14.1.tgz",
-          "integrity": "sha512-ysxwsnTKdAx96aTRdhDOCQfDgbHnt8SK0KY8SEjO0wHinhWOFTESbjVCMPbU1uGXg/ch4lifqx0wfjOawU2+WA==",
-          "dev": true
-        }
       }
     },
     "@apollo/usage-reporting-protobuf": {
@@ -10199,25 +10112,25 @@
       "dev": true
     },
     "@apollo/utils.keyvaluecache": {
-      "version": "1.0.2",
-      "resolved": "https://registry.npmjs.org/@apollo/utils.keyvaluecache/-/utils.keyvaluecache-1.0.2.tgz",
-      "integrity": "sha512-p7PVdLPMnPzmXSQVEsy27cYEjVON+SH/Wb7COyW3rQN8+wJgT1nv9jZouYtztWW8ZgTkii5T6tC9qfoDREd4mg==",
+      "version": "2.1.0",
+      "resolved": "https://registry.npmjs.org/@apollo/utils.keyvaluecache/-/utils.keyvaluecache-2.1.0.tgz",
+      "integrity": "sha512-WBNI4H1dGX2fHMk5j4cJo7mlXWn1X6DYCxQ50IvmI7Xv7Y4QKiA5EwbLOCITh9OIZQrVX7L0ASBSgTt6jYx/cg==",
       "requires": {
-        "@apollo/utils.logger": "^1.0.0",
-        "lru-cache": "7.10.1 - 7.13.1"
+        "@apollo/utils.logger": "^2.0.0",
+        "lru-cache": "^7.14.1"
       },
       "dependencies": {
         "lru-cache": {
-          "version": "7.13.1",
-          "resolved": "https://registry.npmjs.org/lru-cache/-/lru-cache-7.13.1.tgz",
-          "integrity": "sha512-CHqbAq7NFlW3RSnoWXLJBxCWaZVBrfa9UEHId2M3AW8iEBurbqduNexEUCGc3SHc6iCYXNJCDi903LajSVAEPQ=="
+          "version": "7.14.1",
+          "resolved": "https://registry.npmjs.org/lru-cache/-/lru-cache-7.14.1.tgz",
+          "integrity": "sha512-ysxwsnTKdAx96aTRdhDOCQfDgbHnt8SK0KY8SEjO0wHinhWOFTESbjVCMPbU1uGXg/ch4lifqx0wfjOawU2+WA=="
         }
       }
     },
     "@apollo/utils.logger": {
-      "version": "1.0.0",
-      "resolved": "https://registry.npmjs.org/@apollo/utils.logger/-/utils.logger-1.0.0.tgz",
-      "integrity": "sha512-dx9XrjyisD2pOa+KsB5RcDbWIAdgC91gJfeyLCgy0ctJMjQe7yZK5kdWaWlaOoCeX0z6YI9iYlg7vMPyMpQF3Q=="
+      "version": "2.0.0",
+      "resolved": "https://registry.npmjs.org/@apollo/utils.logger/-/utils.logger-2.0.0.tgz",
+      "integrity": "sha512-o8qYwgV2sYg+PcGKIfwAZaZsQOTEfV8q3mH7Pw8GB/I/Uh2L9iaHdpiKuR++j7oe1K87lFm0z/JAezMOR9CGhg=="
     },
     "@apollo/utils.printwithreducedwhitespace": {
       "version": "2.0.0",
diff --git a/package.json b/package.json
index c6e5e92..33164d9 100644
--- a/package.json
+++ b/package.json
@@ -51,7 +51,7 @@
   },
   "dependencies": {
     "@apollo/utils.fetcher": "^2.0.0",
-    "@apollo/utils.keyvaluecache": "^1.0.2",
+    "@apollo/utils.keyvaluecache": "^2.0.0",
     "@types/http-cache-semantics": "^4.0.1",
     "http-cache-semantics": "^4.1.0",
     "lodash.isplainobject": "^4.0.6",
diff --git a/src/__tests__/RESTDataSource.test.ts b/src/__tests__/RESTDataSource.test.ts
index ba1a4a5..cca4ef2 100644
--- a/src/__tests__/RESTDataSource.test.ts
+++ b/src/__tests__/RESTDataSource.test.ts
@@ -760,7 +760,7 @@ describe('RESTDataSource', () => {
           override baseURL = 'https://api.example.com';
 
           override cacheKeyFor(url: URL, _request: RequestOptions) {
-            const urlNoSearchParams = new URL(url);
+            const urlNoSearchParams = new URL(url.toString());
             urlNoSearchParams.search = '';
             return urlNoSearchParams.toString();
           }