From c4d8797979da6b1a20899151a5659568fabeac51 Mon Sep 17 00:00:00 2001 From: Aleix Puig <94959119+aleixpuigb@users.noreply.github.com> Date: Tue, 13 Feb 2024 14:04:51 +0000 Subject: [PATCH] CL release v2024-02-13 (#2280) CL release v2024-02-13 --- cl-base.owl | 1054 +- cl.obo | 5097 +-- patterns/definitions.owl | 4 +- src/ontology/diffs/cl-diff.md | 27709 +++++++++++++++- .../reports/cl-edit.owl-obo-report.tsv | 3 + .../subsets/blood_and_immune_upper_slim.json | 666 +- .../subsets/blood_and_immune_upper_slim.obo | 480 +- .../subsets/blood_and_immune_upper_slim.owl | 1343 +- .../subsets/blood_and_immune_upper_slim.tsv | 789 +- src/ontology/subsets/eye_upper_slim.json | 768 +- src/ontology/subsets/eye_upper_slim.obo | 624 +- src/ontology/subsets/eye_upper_slim.owl | 2146 +- src/ontology/subsets/eye_upper_slim.tsv | 643 +- .../general_cell_types_upper_slim.json | 614 +- .../subsets/general_cell_types_upper_slim.obo | 469 +- .../subsets/general_cell_types_upper_slim.owl | 1231 +- .../subsets/general_cell_types_upper_slim.tsv | 555 +- src/ontology/subsets/kidney_upper_slim.json | 717 +- src/ontology/subsets/kidney_upper_slim.obo | 601 +- src/ontology/subsets/kidney_upper_slim.owl | 2090 +- src/ontology/subsets/kidney_upper_slim.tsv | 750 +- subsets/blood_and_immune_upper_slim.json | 666 +- subsets/blood_and_immune_upper_slim.obo | 480 +- subsets/blood_and_immune_upper_slim.owl | 1343 +- subsets/blood_and_immune_upper_slim.tsv | 789 +- subsets/eye_upper_slim.json | 768 +- subsets/eye_upper_slim.obo | 624 +- subsets/eye_upper_slim.owl | 2146 +- subsets/eye_upper_slim.tsv | 643 +- subsets/general_cell_types_upper_slim.json | 614 +- subsets/general_cell_types_upper_slim.obo | 469 +- subsets/general_cell_types_upper_slim.owl | 1231 +- subsets/general_cell_types_upper_slim.tsv | 555 +- subsets/kidney_upper_slim.json | 717 +- subsets/kidney_upper_slim.obo | 601 +- subsets/kidney_upper_slim.owl | 2090 +- subsets/kidney_upper_slim.tsv | 750 +- 37 files changed, 45885 insertions(+), 16954 deletions(-) diff --git a/cl-base.owl b/cl-base.owl index 5a8b0a88c..0d594722c 100644 --- a/cl-base.owl +++ b/cl-base.owl @@ -17,7 +17,7 @@ xmlns:ubprop="http://purl.obolibrary.org/obo/ubprop#" xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"> - + An ontology of cell types. Cell Ontology @@ -33,7 +33,7 @@ See PMID:15693950, PMID:12799354, PMID:20123131, PMID:21208450; Contact Alexander Diehl, addiehl@buffalo.edu, University at Buffalo. - 2024-01-04 + 2024-02-13 @@ -724,8 +724,8 @@ OBSOLETE A relation between a cell and molecule or complex such that every instance of the cell has a high number of instances of that molecule expressed on the cell surface. For the formal definition, see Masci et al (PMID:19243617). + - Replaced with RO:0015015, see https://github.com/obophenotype/cell-ontology/issues/1481 obsolete has_high_plasma_membrane_amount true @@ -742,8 +742,8 @@ OBSOLETE A relation between a cell and molecule or complex such that every instance of the cell has a low number of instances of that molecule expressed on the cell surface. For the formal definition, see Masci et al (PMID:19243617). + - Replaced with RO:0015016, see https://github.com/obophenotype/cell-ontology/issues/1481 obsolete has_low_plasma_membrane_amount true @@ -787,6 +787,7 @@ WBbt:0004017 XAO:0003012 FBbt:00007002 + The definition of cell is intended to represent all cells, and thus a cell is defined as a material entity and not an anatomical structure, which implies that it is part of an organism (or the entirety of one). cell @@ -809,6 +810,7 @@ primary cell culture cell unpassaged cultured cell primary cell line cell + Covers cells actively being cultured or stored in a quiescent state for future use. primary cultured cell @@ -847,11 +849,12 @@ Covers cells actively being cultured or stored in a quiescent state for future u OBSOLETE. A cell that is found in a natural setting, which includes multicellular organism cells 'in vivo' (i.e. part of an organism), and unicellular organisms 'in environment' (i.e. part of a natural environment). + CARO:0000013 cell in vivo + - https://github.com/obophenotype/cell-ontology/issues/2124 obsolete native cell true @@ -934,6 +937,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u neuronal receptor cell (sensu Animalia) + neuronal receptor cell @@ -1099,6 +1103,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u MA:0002765 VHOG:0001531 ncithesaurus:Spermatogenic_Cell + male germ cell https://github.com/obophenotype/cell-ontology/issues/574 @@ -1246,6 +1251,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u sperm cell spermatozoid spermatozoon + sperm @@ -1320,6 +1326,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u MA:0000388 VHOG:0001530 ncithesaurus:Egg + female germ cell @@ -1404,6 +1411,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u WBbt:0006797 FBbt:00004886 oogonium + oocyte @@ -1445,6 +1453,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u An undifferentiated germ cell that proliferates rapidly and gives rise to oocytes. FMA:83673 + oogonial cell @@ -1637,6 +1646,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u + glioblast @@ -1656,6 +1666,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u BTO:0000930 FMA:70563 neuroblast + neuroblast (sensu Vertebrata) @@ -1743,6 +1754,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u CALOHA:TS-2086 FMA:63368 animal stem cell + This term applies to metazoan. For plant stem cells, consider using PO:0004011 ‘initial cell’ or its parent PO:0004010 ‘meristematic cell’. @@ -1798,6 +1810,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u epithelial stem cell + epithelial fate stem cell @@ -1890,6 +1903,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u HSC colony forming unit hematopoietic + Markers differ between species, and two sets of markers have been described for mice. HSCs are reportedly CD34-positive, CD45-positive, CD48-negative, CD150-positive, CD133-positive, and CD244-negative. hematopoietic stem cell @@ -1939,6 +1953,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u colony forming unit erythroid erythroid stem cell + erythroid progenitor cell @@ -2372,6 +2387,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u FMA:86684 NSC neuronal stem cell + neural stem cell @@ -2442,6 +2458,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u multipotential myeloid stem cell myeloid stem cell pluripotent stem cell (bone marrow) + This cell type is intended to be compatible with any vertebrate common myeloid progenitor. For mammalian CMP known to be CD34-positive, please use the term 'common myeloid progenitor, CD34-positive' (CL_0001059). common myeloid progenitor @@ -2544,6 +2561,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u colony forming unit erythroid megakaryocyte megakaryocyte/erythrocyte progenitor megakaryocyte/erythroid progenitor cell + MEPs are reportedly CD19-negative, CD34-negative, CD45RA-negative, CD110-positive, CD117-positive, and SCA1-negative and reportedly express the transcription factors GATA-1 and NF-E2. megakaryocyte-erythroid progenitor cell @@ -2594,6 +2612,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u early lymphocyte progenitor lymphoid stem cell lymphopoietic stem cell + CLP are CD7-positive, CD10-positive, CD19-negative, CD34-positive, CD45RA-positive, CD79a-negative, CD127-positive, AA4.1-positive, RAG-negative, Sca-1-low, sIgM-negative, sIgD-negative, TdT-negative, Vpre-B-negative, and pre-BCR-negative. Expression of transcription factors include E2A-positive, EBF-positive, Ikaros-negative, PU.1-negative, and Pax5-negative. common lymphoid progenitor @@ -2682,6 +2701,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u BTO:0000125 FMA:84782 blast cell + define using PATO mulit-potent or oligopotent? non-terminally differentiated cell @@ -2734,6 +2754,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u FMA:63877 NCIT:C12482 VHOG:0001482 + These cells may be vimentin-positive, fibronectin-positive, fsp1-positive, MMP-1-positive, collagen I-positive, collagen III-positive, and alpha-SMA-negative. @@ -2941,6 +2962,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u BTO:0001593 CALOHA:TS-0720 FMA:66780 + non-encoded relationships from VSAO - capable_of_producing VSAO:0000020 osteoblast @@ -2992,6 +3014,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u A cell that has a filiform extrusion of the cell surface. VHOG:0001532 XAO:0000031 + ciliated cell @@ -3018,6 +3041,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u BTO:0001724 FMA:70550 ependymocyte + ependymal cell @@ -3052,6 +3076,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u WBbt:0003672 FBbt:00000124 epitheliocyte + epithelial cell @@ -3084,6 +3109,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u An epithelial cell that has a cilia. FMA:70605 + ciliated epithelial cell @@ -3111,6 +3137,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u An epithelial cell that is part of a duct. + duct epithelial cell @@ -3165,6 +3192,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u An endothelial cell that lines the vasculature. cuboidal endothelial cell of vascular tree + blood vessel endothelial cell @@ -3201,8 +3229,8 @@ Covers cells actively being cultured or stored in a quiescent state for future u + - https://github.com/obophenotype/cell-ontology/issues/1149 obsolete barrier epithelial cell true @@ -3233,6 +3261,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube. + columnar/cuboidal epithelial cell @@ -3251,6 +3280,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u CALOHA:TS-1249 + squamous epithelial cell @@ -3271,6 +3301,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u FMA:66773 mesotheliocyte + mesothelial cell @@ -3303,6 +3334,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u + stratified epithelial cell @@ -3352,6 +3384,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u A cell found predominately in the blood. FMA:62844 MESH:D001773 + blood cell @@ -3394,6 +3427,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u An epithelial cell of the lung. BTO:0004299 lung epithelial cell + epithelial cell of lung @@ -3474,6 +3508,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u T-lymphocyte immature T cell mature T cell + T cell @@ -3498,7 +3533,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - https://github.com/obophenotype/cell-ontology/issues/1935 + Obsoleted as there is no need for a term specific for vertebrates. obsolete germ line stem cell (sensu Vertebrata) @@ -3510,7 +3545,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - https://github.com/obophenotype/cell-ontology/issues/1935 + Obsoleted as there is no need for a term specific for nematods and protostomes. obsolete germ line stem cell (sensu Nematoda and Protostomia) @@ -3522,7 +3557,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - https://github.com/obophenotype/cell-ontology/issues/1935 + Obsoleted as there is no need for a term specific for nematods and protostomes. obsolete male germ line stem cell (sensu Nematoda and Protostomia) @@ -3534,7 +3569,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - https://github.com/obophenotype/cell-ontology/issues/1935 + Obsoleted as there is no need for a term specific for nematods and protostomes. obsolete female germ line stem cell (sensu Nematoda and Protostomia) @@ -3546,7 +3581,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - https://github.com/obophenotype/cell-ontology/issues/1935 + Obsoleted as there is no need for a term specific for vertebrates. obsolete male germ line stem cell (sensu Vertebrata) @@ -3558,7 +3593,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u - https://github.com/obophenotype/cell-ontology/issues/1935 + Obsoleted as there is no need for a term specific for vertebrates. obsolete female germ line stem cell (sensu Vertebrata) @@ -3612,6 +3647,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u macrophagocytus stellatus stellate cell of von Kupffer von Kupffer cell + Markers: Mouse: F4/80+, CD11b-low, CD68+, sialoadhesin+, CD163/SRCR+; role or process: immune, antigen-presentation, clearance of senescent erythrocytes, iron metabolism. Kupffer cells are also reportedly C3aR-positive, CD14-low, CD54-positive, CD88-positive, and CD284-positive. They are also capable of producing IL-1, IL-6, TNF-alpha, nitric oxide, PGD2, PGE2, PGF2alpha, and TXA2. Kupffer cell @@ -3698,6 +3734,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u FMA:66781 MESH:D010010 chondroclast + Morphology: Highly vesicular; markers: Surface: RANK, cFMS (MCSF receptor); Secreted: cathepsin K and TRAP (tartate resistant acid phosphatase); transcription factors: PU.1, cFOS, MITF, NFkB (p52); role or process: tissue remodelling: bone resorption; lineage: hematopoietic, myeloid. osteoclast @@ -3795,6 +3832,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u granular leucocyte granular leukocyte polymorphonuclear leukocyte + granulocyte @@ -3826,6 +3864,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u + neuron associated cell @@ -4037,6 +4076,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u mastocyte tissue basophil + Mast cells are generally integrin beta-7-negative and positive for TLR2, TLR3, TLR4, TLR5, TLR7, TLR9, C3aR, C5aR, CR3, CR4, VEGF, FGF2, and renin. They can express MHC Class I and II on their surface. Activated murine mast cells (IgE+Antigen) were capable of expressing the following co-stimulatory molecules: CD95 (Fas), CD120b, CD137 (4-1BB), CD153 (CD30L), CD154 (CD40L), GITR, ICOSL, OX40L, PD-L1, and PD-L2. Note that there was some mouse strain variation. Mast cells have also been demonstrated to produce bFGF, CCL2, CCL4, CCL5, CCL11, CCL20, CXCL2, CXCL8, CXCL10, GM-CSF, IFN-gamma, IL-1, IL-2, IL-3, IL-8, IL-10, IL-11, IL-12, IL-13, IL-16, IL-25, IL-18, MIP-1, prostaglandin D2, SCF, TGF-beta, TNF-alpha, TSLP, VEGF, and XCL1. They express the transcription factors Transcription factors AP-1, GATA1, MITF, Notch2, PIAS3, PU.1, and STAT5. mast cell @@ -4127,6 +4167,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u FMA:67313 WBbt:0005113 FBbt:00005125 + interneuron @@ -4151,6 +4192,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u WBbt:0005409 FBbt:00005123 motoneuron + motor neuron @@ -4222,6 +4264,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u A type of interneuron that has two neurites, usually an axon and a dendrite, extending from opposite poles of an ovoid cell body. FMA:67282 + bipolar neuron @@ -4399,9 +4442,10 @@ Covers cells actively being cultured or stored in a quiescent state for future u OBSOLETE A neuron that is part of nerve found outside the central nervous system. + FMA:84664 - Merging into CL:2000032, see https://github.com/obophenotype/cell-ontology/issues/1069 + Merging into CL:2000032. obsolete peripheral neuron true @@ -4443,6 +4487,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u A vertebrate phagocyte with a single nucleus. BTO:0001433 + mononuclear phagocyte @@ -4470,6 +4515,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u FMA:72552 cell of surface ectoderm surface ectoderm cell + surface ectodermal cell @@ -4486,6 +4532,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u CALOHA:TS-0278 FMA:66772 endotheliocyte + From FMA: 9.07.2001: Endothelial cell has always been classified as a kind of epithelial cell, specifically a squamous cell but that is not true. First, endothelial cell can either be squamous or cuboidal (e.g. high-endothelial cell) and secondly, it has different embryological derivation (mesodermal) than a true epithelial cell (ectodermal and endodermal). The basis for present classification is the fact that it comprises the outermost layer or lining of anatomical structures (location-based) but a better structural basis for the differentia is the cytoskeleton of the cell. Endothelial cell has vimentin filaments while an epithelial cell has keratin filaments. [Onard]. endothelial cell @@ -4590,6 +4637,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u Golgi neuron cerebellar Golgi neuron cerebellum Golgi cell + cerebellar Golgi cell @@ -4607,6 +4655,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u A neuron of the vertebrate central nervous system that is small in size. This general class includes small neurons in the granular layer of the cerebellar cortex, cerebral cortex neurons that are not pyramidal cells and small neurons without axons found in the olfactory bulb. BTO:0003393 + granule cell @@ -4637,6 +4686,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u Purkinje's cell cerebellar Purkinje cell cerebellum Purkinje cell + Purkinje cell @@ -4665,6 +4715,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u A neuron that has dendritic processes radiating from the cell body forming a star-like shape. BTO:0002316 + stellate neuron @@ -4692,6 +4743,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u + neuron associated cell (sensu Vertebrata) @@ -4700,9 +4752,9 @@ Covers cells actively being cultured or stored in a quiescent state for future u + This is a grouping class that is no longer needed or wanted. obsolete glial cell (sensu Nematoda and Protostomia) - https://github.com/obophenotype/cell-ontology/issues/715 true @@ -4719,6 +4771,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u FBbt:00005144 neuroglial cell neuroglia + Not all glial cells develop from glioblasts, with microglia developing from the mesoderm instead. See https://github.com/obophenotype/cell-ontology/issues/1571 glial cell @@ -4748,6 +4801,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u FMA:54538 macrogliocyte macroglia + macroglial cell @@ -4777,6 +4831,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u CALOHA:TS-0060 FMA:54537 astrocytic glia + Astrocytes are reportedly CD68-negative, CD121a-positive, CD184-positive, CD192-positive, CRF-positive, EGFR-positive, GFAP-positive, GLUT1-positive, MBP-negative, and NGFR-positive. astrocyte @@ -4826,6 +4881,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u FMA:54540 OLs oligodendroglia + Oligodendrocytes are reportedly MDP-positive and CD4-negative. oligodendrocyte @@ -4916,6 +4972,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u microgliocyte MF.microglia.CNS microglia + Unlike macroglial cells, microglial cells arise from hematopoietic stem cells in the yolk sac during early embryogenesis that populate the central nervous system. They derive from embryonic mesoderm and are not from neuroectoderm where glioblast develops from. Markers: Mouse: CD11b+, F4/80+, CD68+. They represent ~12% of the cells in the CNS, but they are not uniformly distributed within the CNS. A normal adult mouse brain has approximately 3.5x10e6 microglia. Microglia are also reportedly CD3-negative, CD4-positive, CD8-negative, CD11b-positive, CD11c-high, CD14-negative, CD19-negative, CD45-low, CD56-negative, CD163-negative, CD200R-positive, CD281-positive, CD282-positive, CD283-positive, CD284-positive, CD285-positive, CD286-positive, CD287-positive, CD288-positive, CD289-positive, Gr1-negative, nestin-positive, and PU.1-positive. microglial cell @@ -4991,6 +5048,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u + gut endothelial cell @@ -5016,6 +5074,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u CALOHA:TS-0172 FMA:70614 + corneal endothelial cell @@ -5072,6 +5131,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u mesenchymal stromal cell mesenchymal stromal cells stem cells, mesenchymal + Many but not all mesenchymal cells derive from the mesoderm. MSCs are reportedly CD3-negative, CD4-negative, CD5-negative, CD8-negative, CD11a-negative, CD11b-negative, CD14-negative, CD19-negative, CD29-positive, CD31-negative, CD34-negative, CD38-negative, CD40-negative, CD44-positive, CD45-negative, CD49-positive, CD54-positive, CD66b-negative, CD79a-negative, CD80-negative, CD102-positive, CD106-positive, CD117-positive, CD121a-positive, CD121b-positive, CD123-positive, CD124-positive, CD133-negative, CD146-positive, CD166-positive, CD271-positive, B220-negative, Gr1-negative, MHCI-positive, MHCII-negative, SSEA4-negative, sca1-positive, Ter119-negative, and glycophorin A-negative. Cultured MSCs are capable of producing stem cell factor, IL7, IL8, IL11, TGF-beta, cofilin, galectin-1, laminin-receptor 1, cyclophilin A, and MMP-2. mesenchymal stem cell https://github.com/obophenotype/cell-ontology/issues/474 @@ -5171,6 +5231,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u An inactive fibroblast; cytoplasm is sparse, endoplasmic reticulum is scanty with flattened nucleus. Term used by some histologists; when fibroblasts become relatively inactive in fiber formation. However, this cell has the potential for fibrogenesis in quiescent connective tissue of the adult, as well as during development, other histologists prefer to use the term fibroblast in all circumstances. These cells represent ~0.5% of peripheral blood leukocytes. FMA:63879 + Cultured human fibrocytes are MHCI-positive, MHCII-positive, CD1a-negative, CD3-negative, CD4-negative, CD8-negative, CD10-negative, CD11b-positive, CD13-positive, CD14-negative, CD16-negative, CD18-positive, CD19-negative, CD25-negative, CD29-positive, CD32-positive, CD33-negative, CD34-positive, CD38-negative, CD40-positive, CD44-negative, CD45RO-positive, CD49a-positive, CD49b-positive, CD49c-negative, CD49d-negative, CD49e-positive, CD49f-negative, CD56-negative, CD58-positive, CD61-positive, CD64-positive, CD70-negative, CD71-positive, CD80-positive, CD83-negative, CD86-positive, CD103-negative, CD105-positive, CD181-positive, CD182-negative, CD183-positive, CD184-positive, CD185-negative, CD186-negative, CD191-positive, CD192-negative, CD193-positive, CD194-positive, CD195-positive, CD196-negative, CD197-positive, CD199-positive, desmin-negative, F4/80-positive, Gr1-positive, LSP-1-positive, MHCI-positive, MHCII-positive, alpha-SMA-negative, TCRab-negative, TCRgd-negative, and vimentin-positive. Fibrocytes are also capable of secreting angiogenin, bFGF, CCL2, CCL3, CCL4, CCL8, CXCL1, type I collagen, type III collagen, CTGF, fibronectin, GM-CSF, IL-1a, IL-6, IL-8, IL-10, M-CSF, MMP-9, PDGF-A, TGF-alpha, TGF-beta1, TNF-alpha, and VEGF-A. fibrocyte @@ -5217,6 +5278,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u FMA:63880 adipose cell fat cell + adipocyte @@ -5288,6 +5350,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u CALOHA:TS-0138 FMA:66782 cartilage cell + chondrocyte @@ -5441,6 +5504,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u A cell capable of processing and presenting lipid and protein antigens to T cells in order to initiate an immune response. APC + Note change of name; nearly all somatic cells can present antigens to T cells via MHC Class I complexes leading to effector responses, but professional antigen presenting cells constitutively express MHC Class II as well as costimulatory molecules, and thus can initiate immune responses via T cells. professional antigen presenting cell @@ -5516,6 +5580,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u MESH:D008544 VHOG:0001679 melanophore + melanocyte @@ -5553,6 +5618,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u A specialized epithelial cell that is capable of synthesizing and secreting certain biomolecules. CALOHA:TS-2085 FMA:86494 + glandular epithelial cell @@ -5581,6 +5647,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u A cell that specializes in controlled release of one or more substances. BTO:0003659 FMA:86916 + secretory cell @@ -5672,6 +5739,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u gastric chief cell pepsinogen secreting cell zymogenic cell + peptic cell @@ -5756,6 +5824,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u BTO:0004811 FMA:14119 Clara cell + club cell @@ -5797,6 +5866,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u FMA:13148 http://en.wikipedia.org/wiki/Goblet_cell chalice cell + goblet cell @@ -5811,8 +5881,8 @@ Covers cells actively being cultured or stored in a quiescent state for future u + - https://github.com/obophenotype/cell-ontology/issues/427 obsolete acid secreting cell true @@ -5835,6 +5905,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u BTO:0001780 FMA:62901 oxyntic cell + parietal cell @@ -5881,6 +5952,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u FMA:83809 endocrinocyte + endocrine cell @@ -5903,6 +5975,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u BTO:0003865 FMA:62930 MESH:D019858 + enteroendocrine cell @@ -5940,6 +6013,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u FBbt:00005130 neurosecretory cell neurosecretory neuron + The neurosecretory cell is neither an ordinary neuron nor an endocrine cell, but a combination of both. Its neuronal features resemble those of ordinary neurons concerning both structure and function. The production of a visible secretory material marks the neurosecretory neuron as a gland cell, and the fact that extractable cellular products act in the manner of hormones places it in the realm of endocrine elements. @@ -5978,6 +6052,7 @@ The modern definition of neurosecretion has evolved to include the release of an BTO:0000259 FMA:69263 phaeochromocyte + chromaffin cell @@ -6071,6 +6146,7 @@ The modern definition of neurosecretion has evolved to include the release of an pancreatic islet core type B enteroendocrine cell beta cell islet + Pancreatic beta cells are also reportedly CD284-positive. Upon activation, they upregulate their CD14 expression. type B pancreatic cell @@ -6220,6 +6296,7 @@ The modern definition of neurosecretion has evolved to include the release of an MESH:D050416 alpha cell of islet of Langerhans pancreatic alpha cell + pancreatic A cell @@ -6289,6 +6366,7 @@ The modern definition of neurosecretion has evolved to include the release of an pancreatic D-cell pancreatic delta cell somatostatin-secreting pancreatic cell + pancreatic D cell @@ -6424,6 +6502,7 @@ The modern definition of neurosecretion has evolved to include the release of an FMA:72297 MESH:D007985 interstitial cell of Leydig + Note that the Amphibian Anatomy Ontology (AA) has a class 'leydig cells' but this is unrelated Leydig cell @@ -6486,9 +6565,9 @@ The modern definition of neurosecretion has evolved to include the release of an A cell whose primary function is intermediary metabolism. + Removing this grouping class, because the groupings are incomplete and too hard to maintain. obsolete metabolising cell - https://github.com/obophenotype/cell-ontology/issues/720 true @@ -6540,6 +6619,7 @@ The modern definition of neurosecretion has evolved to include the release of an BTO:0000575 CALOHA:TS-0454 FMA:14515 + Hepatocytes are reportedly MHC Class I-positive and MHC Class II-positive. hepatocyte @@ -6562,6 +6642,7 @@ The modern definition of neurosecretion has evolved to include the release of an A cell whose primary function is to shorten. + contractile cell @@ -6600,6 +6681,7 @@ The modern definition of neurosecretion has evolved to include the release of an FMA:67799 basket epithelial cell myoepitheliocyte + myoepithelial cell @@ -6625,6 +6707,7 @@ The modern definition of neurosecretion has evolved to include the release of an An animal cell that has characteristics of both a fibroblast cell and a smooth muscle cell. MFB + Myofibroblasts are alpha-SMA-positive, CD34-negative, CD45-negative. They are reportedly capable of secreting IL-1beta, IL-6, and TNF-alpha. myofibroblast cell @@ -6669,6 +6752,7 @@ The modern definition of neurosecretion has evolved to include the release of an FBbt:00005074 muscle fiber myocyte + muscle cell https://www.swissbiopics.org/api/image/Muscle_cells.svg @@ -6701,6 +6785,7 @@ The modern definition of neurosecretion has evolved to include the release of an CALOHA:TS-2158 FMA:9727 skeletal muscle cell + cell of skeletal muscle @@ -6726,6 +6811,7 @@ The modern definition of neurosecretion has evolved to include the release of an A muscle cell that develops tension more slowly than a fast-twitch fiber. slow muscle fiber + slow muscle cell @@ -6756,6 +6842,7 @@ The modern definition of neurosecretion has evolved to include the release of an A muscle cell that can develop high tension rapidly. It is usually innervated by a single alpha neuron. glycolytic muscle fiber + fast muscle cell @@ -6798,6 +6885,7 @@ The modern definition of neurosecretion has evolved to include the release of an SMCs myocytes, smooth muscle smooth muscle fiber + smooth muscle cell @@ -7192,6 +7280,7 @@ The modern definition of neurosecretion has evolved to include the release of an A specialized cell involved in gustatory sensory perception. FMA:67910 taste bud cell + taste receptor cell @@ -7223,6 +7312,7 @@ The modern definition of neurosecretion has evolved to include the release of an BTO:0001060 CALOHA:TS-0868 FMA:86740 + photoreceptor cell https://www.swissbiopics.org/api/image/Photoreceptor_cell.svg @@ -7356,6 +7446,7 @@ The modern definition of neurosecretion has evolved to include the release of an CALOHA:TS-0922 FMA:72298 VHOG:0001348 + Sertoli cell @@ -7495,6 +7586,7 @@ The modern definition of neurosecretion has evolved to include the release of an FMA:72554 mesoblast mesoderm cell + mesodermal cell @@ -7735,6 +7827,7 @@ The modern definition of neurosecretion has evolved to include the release of an RBC red blood cell + erythrocyte @@ -7798,6 +7891,7 @@ The modern definition of neurosecretion has evolved to include the release of an blood platelet enucleate thrombocyte + Platelets are reportedly CCR1-positive, CCR2-negative, CCR3-positive, CCR4-positive, CCR5-negative, CCR6-negative, CCR7-negative, CCR8-negative, CCR9-negative, CCR10-negative, CD16-positive, CD23-positive, CD32-positive, CD40-positive, CD41-positive CD42-positive, CD61-positive, CD62P-positive, CD64-positive, CD89-positive, CD102-positive, CD147-positive (activated platelets), CD154-positive (activated platelets), CD162-positive, CD209, CD282-positive, CD284-positive, CD289-positive, CD181-negative, CD182-negative, CD183-negative, CD184-positive, CLEC2-positive, GPVI-positive, JAMC-positive, PAR1-positive, PAR2-negative, PAR3-positive, PAR4-positive, TSP1-positive, and TXA2R-positive. Platelets can reportedly produce CCL2, CCL3, CCL5, CCL7, CCL17, CD40L, CXCL1, CXCL4, CXCL4L1, CXCL5, CXCL7, CXCL8, CXCL12, EGF, factor V, factor VII, factor XI, factor XIII, bFGF, histamine, IGF-1, IL-1beta, PAI-1, PDGF, plasminogen, protein S, serotonin, TGF-beta, TFPI, VEGF, and vWF. platelet @@ -7847,6 +7941,7 @@ The modern definition of neurosecretion has evolved to include the release of an BTO:0001044 FMA:83806 MESH:D010586 + phagocyte @@ -7898,6 +7993,7 @@ The modern definition of neurosecretion has evolved to include the release of an MESH:D008264 histiocyte + Morphology: Diameter 30_M-80 _M, abundant cytoplasm, low N/C ratio, eccentric nucleus. Irregular shape with pseudopods, highly adhesive. Contain vacuoles and phagosomes, may contain azurophilic granules; markers: Mouse & Human: CD68, in most cases CD11b. Mouse: in most cases F4/80+; role or process: immune, antigen presentation, & tissue remodelling; lineage: hematopoietic, myeloid. @@ -7954,6 +8050,7 @@ The modern definition of neurosecretion has evolved to include the release of an B-cell B-lymphocyte + B cell @@ -8055,6 +8152,7 @@ The modern definition of neurosecretion has evolved to include the release of an FMA:70548 Merkel's cell + Merkel cell @@ -8077,9 +8175,9 @@ The modern definition of neurosecretion has evolved to include the release of an A non-neuronal cell of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu. Form the myelin insulation of nervous pathways, guide neuronal migration during development, and exchange metabolites with neurons. Neuroglia have high-affinity transmitter uptake systems, voltage-dependent and transmitter-gated ion channels, and can release transmitters, but their role in signaling (as in many other functions) is unclear. + This is a grouping class that is no longer needed or wanted. obsolete glial cell (sensu Vertebrata) - https://github.com/obophenotype/cell-ontology/issues/715 true @@ -8248,6 +8346,7 @@ The modern definition of neurosecretion has evolved to include the release of an + eurydendroid cell @@ -8287,6 +8386,7 @@ The modern definition of neurosecretion has evolved to include the release of an MESH:D005057 + eukaryotic cell @@ -8735,6 +8835,7 @@ The modern definition of neurosecretion has evolved to include the release of an + eye photoreceptor cell @@ -9179,6 +9280,7 @@ The modern definition of neurosecretion has evolved to include the release of an FMA:62879 keratinized cell of epidermis malpighian cell + Keratinocytes are reportedly CDw210a-negative, CDw210b-positive, CD281-positive, CD282-positive, CD285-positive, IL22Ra1-positive, Human keratinocytes are reportedly capable of secreting BD-2, BD-3, hCAP-18, CXCL1, CXCL5, CXCL8, elafin, MMP-3, NGAL, PDGF-A, S100A7, S100A8, and S100A9. Transcription factors: STAT3-positive. keratinocyte @@ -9217,6 +9319,7 @@ The modern definition of neurosecretion has evolved to include the release of an BTO:0003687 FMA:62511 serous cell + serous secreting cell @@ -9355,6 +9458,7 @@ The modern definition of neurosecretion has evolved to include the release of an BTO:0003689 mucous cell + mucus secreting cell @@ -9382,9 +9486,9 @@ The modern definition of neurosecretion has evolved to include the release of an + - https://github.com/obophenotype/cell-ontology/issues/1149 obsolete seminal fluid secreting cell true @@ -9407,6 +9511,7 @@ The modern definition of neurosecretion has evolved to include the release of an FMA:62499 alveolar epithelial cell pneumonocyte + pneumocyte @@ -10186,6 +10291,7 @@ The modern definition of neurosecretion has evolved to include the release of an VSMC vascular smooth muscle cell + vascular associated smooth muscle cell @@ -10271,6 +10377,7 @@ The modern definition of neurosecretion has evolved to include the release of an MESH:D000078404 cell of epidermis epithelial cell of skin + epidermal cell @@ -10588,9 +10695,9 @@ The modern definition of neurosecretion has evolved to include the release of an + - https://github.com/obophenotype/cell-ontology/issues/1784 -'neuroendocrine cell' (which has exact synonym "neurosecretory cell") and 'neurosecretory neuron' may all refer to the same cell type. + 'neuroendocrine cell' (which has exact synonym "neurosecretory cell") and 'neurosecretory neuron' may all refer to the same cell type. obsolete neurosecretory neuron true @@ -10727,6 +10834,7 @@ The modern definition of neurosecretion has evolved to include the release of an An elongated fibrocyte that is part of a tendon. The cytoplasm is stretched between the collagen fibres of the tendon. They have a central cell nucleus with a prominent nucleolus. Tendon cells have a well-developed rough endoplasmic reticulum and they are responsible for synthesis and turnover of tendon fibres and ground substance. muscle attachment cell tenocyte + tendon cell @@ -10769,7 +10877,7 @@ The modern definition of neurosecretion has evolved to include the release of an - https://github.com/obophenotype/cell-ontology/issues/1949 + Obsoleted as podocytes are not a distinct cell type from plasmatocytes. obsolete podocyte (sensu Diptera) @@ -10829,6 +10937,7 @@ The modern definition of neurosecretion has evolved to include the release of an A phagocytic hemocyte, responsible for the engulfment of small particles, microbes, and apoptotic tissue debris. It may also secretes antimicrobial peptides and contribute to the production and secretion of proteins of the hemolymph. FBbt:00001685 macrophage + plasmatocyte @@ -10889,6 +10998,7 @@ The modern definition of neurosecretion has evolved to include the release of an + ganglion interneuron @@ -10903,7 +11013,7 @@ The modern definition of neurosecretion has evolved to include the release of an - https://github.com/obophenotype/cell-ontology/issues/1949 + FBbt:00001691 Obsoleted as this is actually the same thing as prohemocytes. @@ -10949,7 +11059,7 @@ The modern definition of neurosecretion has evolved to include the release of an - https://github.com/obophenotype/cell-ontology/issues/1949 + Obsoleted as plasmatocytes are the macrophages (phagocytic cells) of Diptera. obsolete macrophage (sensu Diptera) @@ -11016,7 +11126,7 @@ The modern definition of neurosecretion has evolved to include the release of an - https://github.com/FlyBase/drosophila-anatomy-developmental-ontology/issues/1621 + Obsoleted as the term seems completely unused in the literature. obsolete neuroepidermoblast true @@ -11389,9 +11499,9 @@ The modern definition of neurosecretion has evolved to include the release of an + This is a cell used in tissue engineering and is out of scope for CL. obsolete scaffold cell - https://github.com/obophenotype/cell-ontology/issues/708 true @@ -11508,6 +11618,7 @@ The modern definition of neurosecretion has evolved to include the release of an FMA:62877 reticulum cell + reticular cell https://github.com/obophenotype/cell-ontology/issues/1472 @@ -11738,6 +11849,7 @@ The modern definition of neurosecretion has evolved to include the release of an BTO:0004267 FMA:83037 MESH:D020566 + Due to its unique lineage and distinct function, this is not a type of dendritic cell; CL:0000451. follicular dendritic cell @@ -11986,6 +12098,7 @@ The modern definition of neurosecretion has evolved to include the release of an MESH:D003713 interdigitating cell veiled cell + dendritic cell @@ -12047,6 +12160,7 @@ The modern definition of neurosecretion has evolved to include the release of an FMA:63072 MESH:D007801 LC + Originally described in the dendritic cell ontology (DC_CL:0000021 )(PMID:19243617). These cells are also CD1a-high, CD14-negative, CD207-positive (langerin), CD324-positive (E-cadherin), and DCIR-positive. They reside in the epidermis. Langerhans cell @@ -12955,6 +13069,7 @@ The modern definition of neurosecretion has evolved to include the release of an CD4-positive helper T lymphocyte CD4-positive helper T-cell CD4-positive helper T-lymphocyte + CD4-positive helper T cell @@ -13070,6 +13185,7 @@ The modern definition of neurosecretion has evolved to include the release of an An interneuron (also called relay neuron, association neuron or local circuit neuron) is a multipolar neuron which connects afferent neurons and efferent neurons in neural pathways. Like motor neurons, interneuron cell bodies are always located in the central nervous system (CNS). FMA:84776 + inhibitory interneuron @@ -13096,6 +13212,7 @@ The modern definition of neurosecretion has evolved to include the release of an BTO:0002064 FMA:83624 + stromal cell @@ -13130,6 +13247,7 @@ The modern definition of neurosecretion has evolved to include the release of an CALOHA:TS-0729 FMA:18718 granulosa cell of ovary + granulosa cell @@ -13154,6 +13272,7 @@ The modern definition of neurosecretion has evolved to include the release of an A cell found throughout the gastrointestinal tract and in the pancreas. They secrete somatostatin in both an endocrine and paracrine manner. Somatostatin inhibits gastrin, cholecystokinin, insulin, glucagon, pancreatic enzymes, and gastric hydrochloric acid. A variety of substances which inhibit gastric acid secretion (vasoactive intestinal peptide, calcitonin gene-related peptide, cholecystokinin, beta-adrenergic agonists, and gastric inhibitory peptide) are thought to act by releasing somatostatin. FMA:62935 D cell + type D enteroendocrine cell @@ -13179,6 +13298,7 @@ The modern definition of neurosecretion has evolved to include the release of an A flattened stroma cell forming a sheath or theca outside the basal lamina lining the mature ovarian follicle. Thecal interstitial or stromal cells are steroidogenic, and produce primarily androgens which serve as precusors of estrogens in the granulosa cells. BTO:0002850 + theca cell @@ -13276,6 +13396,7 @@ The modern definition of neurosecretion has evolved to include the release of an BTO:0004108 FMA:67609 G cell + type G enteroendocrine cell @@ -13327,6 +13448,7 @@ The modern definition of neurosecretion has evolved to include the release of an An epithelial cell found in the basal part of the intestinal glands (crypts of Lieberkuhn) including the appendix. Paneth cells synthesize and secrete lysozyme and cryptdins. Numerous in the deeper parts of the intestinal crypts, particularly in the duodenum, rich in zinc, contain large acidophilic granules, with irregular apical microvilli and prominent membrane-bound vacuoles containing matrix. BTO:0000993 FMA:62897 + paneth cell @@ -13404,6 +13526,7 @@ The modern definition of neurosecretion has evolved to include the release of an FMA:84797 cardiac muscle progenitor cell cardiomyocyte progenitor cell + cardiac muscle myoblast @@ -13440,6 +13563,7 @@ The modern definition of neurosecretion has evolved to include the release of an FMA:84798 myoblast, smooth muscle satellite cell + smooth muscle myoblast @@ -13693,6 +13817,7 @@ The modern definition of neurosecretion has evolved to include the release of an syncytiotrophoblastic cell plasmidotrophoblast cell syntrophoblast cell + syncytiotrophoblast cell https://github.com/obophenotype/cell-ontology/issues/2100 @@ -13778,6 +13903,7 @@ The modern definition of neurosecretion has evolved to include the release of an + pigmented epithelial cell @@ -13823,6 +13949,7 @@ The modern definition of neurosecretion has evolved to include the release of an A primary neuron (sensu Teleostei) that has a sensory function. + primary sensory neuron (sensu Teleostei) @@ -13999,6 +14126,7 @@ The modern definition of neurosecretion has evolved to include the release of an WBbt:0003679 FBbt:00005106 nerve cell + These cells are also reportedly CD4-negative and CD200-positive. They are also capable of producing CD40L and IFN-gamma. @@ -14052,10 +14180,6 @@ The modern definition of neurosecretion has evolved to include the release of an - - - - @@ -14064,6 +14188,10 @@ The modern definition of neurosecretion has evolved to include the release of an + + + + @@ -14082,6 +14210,7 @@ The modern definition of neurosecretion has evolved to include the release of an FMA:62863 MESH:D008214 VHOG:0001535 + Editors note: consider adding taxon constraint to vertebrata (PMID:18025161) lymphocyte @@ -14176,6 +14305,7 @@ The modern definition of neurosecretion has evolved to include the release of an Th1 T-lymphocyte Th1 cell helper T cell type 1 + This cell type is compatible with the HIPC Lyoplate markers for 'Th1 CD4+ T cell', but its logical definition includes additional known characteristics of T-helper 1 T cells. T-helper 1 cell @@ -14259,6 +14389,7 @@ The modern definition of neurosecretion has evolved to include the release of an Th2 T-lymphocyte Th2 cell helper T cell type 2 + This cell type is compatible with the HIPC Lyoplate markers for 'non-Th1/Th17 CD4+ T cell' (see CL:0001051), but includes the additional necessary and sufficient conditions to allow classification as a T-helper 2 T cell. T-helper 2 cell @@ -14301,10 +14432,6 @@ The modern definition of neurosecretion has evolved to include the release of an - - - - @@ -14357,6 +14484,10 @@ The modern definition of neurosecretion has evolved to include the release of an + + + + @@ -14376,6 +14507,7 @@ The modern definition of neurosecretion has evolved to include the release of an rubriblast pronormoblast + proerythroblast @@ -14404,10 +14536,11 @@ The modern definition of neurosecretion has evolved to include the release of an OBSOLETE. A native cell that is part of some Metazoa. + metazoan cell + - https://github.com/obophenotype/cell-ontology/issues/2124 obsolete animal cell true https://www.swissbiopics.org/api/image/Animal_cells.svg @@ -14753,6 +14886,7 @@ The modern definition of neurosecretion has evolved to include the release of an megakaryocytic progenitor cell promegacaryocyte promegakaryocyte + Lineage negative is described here as CD2-negative, CD3-negative, CD4-negative, CD5-negative, CD8a-negative, CD14-negative, CD19-negative, CD20-negative, CD56-negative, Ly6g-negative, and Ter119-negative. megakaryocyte progenitor cell @@ -14819,6 +14953,7 @@ The modern definition of neurosecretion has evolved to include the release of an + neuronal brush cell @@ -14850,6 +14985,7 @@ The modern definition of neurosecretion has evolved to include the release of an megalocaryocyte megalokaryocyte + Megakaryocytes are reportedly CD181-positive and CD182-positive. megakaryocyte @@ -14930,6 +15066,7 @@ The modern definition of neurosecretion has evolved to include the release of an granulocyte/monocyte progenitor CFU-GM GMP + Originally described in the dendritic cell ontology (DC_CL:0000042)(PMID:19243617). GMPs are reportedly CD16-positive, CD32-positive, CD34-positive, CD38-positive, CD45RA-positive, CD110-negative, CD117-positive, CD123-positive, and SCA1-negative. granulocyte monocyte progenitor cell @@ -15074,6 +15211,7 @@ The modern definition of neurosecretion has evolved to include the release of an CALOHA:TS-0864 MESH:D012156 + reticulocyte @@ -15127,6 +15265,7 @@ The modern definition of neurosecretion has evolved to include the release of an BTO:0004657 FMA:83551 + Morphology: Mononuclear cell, diameter 14-18 _M, fine azurophilic granules; markers: CD11b (shared with many other myeloid cells); location: Adult: bone marrow; Fetal: Liver, Yolk Sac; role or process: hematopoiesis, monocyte development; lineage: hematopoietic, myeloid. promonocyte @@ -15268,6 +15407,7 @@ The modern definition of neurosecretion has evolved to include the release of an amacrine neuron AC ACs + amacrine cell @@ -15545,6 +15685,7 @@ The modern definition of neurosecretion has evolved to include the release of an A mesenchymal cell found in the developing heart and that develops into some part of the heart. These cells derive from intra- and extra-cardiac sources, including the endocardium, epicardium, neural crest, and second heart field. + cardiac mesenchymal cell @@ -15700,6 +15841,7 @@ The modern definition of neurosecretion has evolved to include the release of an CALOHA:TS-0866 FMA:67748 cone + retinal cone cell @@ -15761,6 +15903,7 @@ The modern definition of neurosecretion has evolved to include the release of an CALOHA:TS-0173 FMA:70551 epithelial cell of cornea + corneal epithelial cell @@ -15820,6 +15963,7 @@ The modern definition of neurosecretion has evolved to include the release of an CALOHA:TS-0638 FMA:62864 + Morphology: Mononuclear cell, diameter, 14 to 20 _M, N/C ratio 2:1-1:1. Nucleus may appear in variety of shapes: round, kidney, lobulated, or convoluted. Fine azurophilic granules present; markers: CD11b (shared with other myeloid cells), human: CD14, mouse: F4/80-mid,GR1-low; location: Blood, but can be recruited into tissues; role or process: immune & tissue remodelling; lineage: hematopoietic, myeloid. @@ -15862,6 +16006,7 @@ The modern definition of neurosecretion has evolved to include the release of an Kulchitsky cell argentaffin cell enterochromaffin cell + type EC enteroendocrine cell @@ -16262,6 +16407,7 @@ The modern definition of neurosecretion has evolved to include the release of an FMA:83023 dust cell MF.Lu + Markers: Mouse: F4/80mid, CD11b-/low, CD11c+, CD68+, sialoadhesin+, dectin-1+, MR+, CX3CR1-. alveolar macrophage @@ -16298,6 +16444,7 @@ The modern definition of neurosecretion has evolved to include the release of an MESH:D020895 differentiated enterocyte mature enterocyte + enterocyte @@ -16350,6 +16497,7 @@ The modern definition of neurosecretion has evolved to include the release of an NCIT:C12597 VHOG:0001534 WBbt:0006796 + germ cell @@ -16546,6 +16694,7 @@ The modern definition of neurosecretion has evolved to include the release of an An elongated, spindle-shaped, cell that is located between the basal lamina and the plasmalemma of a muscle fiber. These cells are mostly quiescent, but upon activation they divide to produce cells that generate new muscle fibers. + Skeletal muscle satellite cells are not traditionally referred to as myoblasts. They are a heterogeneous population whose division, following activiation, contributes to the formation of skeletal muscle fibers and to maintenance of the skeletal muscle statelite cell population. skeletal muscle satellite cell @@ -16585,6 +16734,7 @@ The modern definition of neurosecretion has evolved to include the release of an An erythrocyte lacking a nucleus. red blood cell RBC + enucleate erythrocyte @@ -16671,6 +16821,7 @@ The modern definition of neurosecretion has evolved to include the release of an projection neuron pyramidal cell + pyramidal neuron @@ -16794,6 +16945,7 @@ The modern definition of neurosecretion has evolved to include the release of an CALOHA:TS-0870 FMA:67747 rod + retinal rod cell @@ -17372,6 +17524,7 @@ The modern definition of neurosecretion has evolved to include the release of an WBbt:0005190 FBbt:00007228 GABA-ergic neuron + GABAergic neuron @@ -17457,6 +17610,7 @@ The modern definition of neurosecretion has evolved to include the release of an MESH:D061354 acinic cell acinous cell + acinar cell @@ -17521,6 +17675,7 @@ The modern definition of neurosecretion has evolved to include the release of an MESH:D007694 VHOG:0001697 NK cell + natural killer cell @@ -17561,6 +17716,7 @@ The modern definition of neurosecretion has evolved to include the release of an CD4-positive, alpha-beta T lymphocyte CD4-positive, alpha-beta T-cell CD4-positive, alpha-beta T-lymphocyte + CD4-positive, alpha-beta T cell @@ -17604,6 +17760,7 @@ The modern definition of neurosecretion has evolved to include the release of an CD8-positive, alpha-beta T lymphocyte CD8-positive, alpha-beta T-cell CD8-positive, alpha-beta T-lymphocyte + CD8-positive, alpha-beta T cell @@ -17758,6 +17915,7 @@ The modern definition of neurosecretion has evolved to include the release of an A cell whose primary function is to support other cell types. BTO:0002315 supportive cell + supporting cell @@ -17818,6 +17976,7 @@ The modern definition of neurosecretion has evolved to include the release of an fat-storing cell lipocyte vitamin A-storing cells + Hepatic stellate cells are CD271-positive, desmin-positive, DDR-2-positive, GFAP-positive, synamin-positive, synaptophysin-positive, vimentin-positive, They are capable of producing angiotensin II, fibronectin, laminin, MMP-1, MMP-2, MMP-3, MMP-9, MMP-11, TGF-beta1, TIMP-1, TIMP-2, type I collagen, type III collagen, type IV collagen, and type VI collagen. hepatic stellate cell @@ -17928,6 +18087,7 @@ The modern definition of neurosecretion has evolved to include the release of an Muller cell Muller glia Müller cell + Mueller cell @@ -18151,6 +18311,7 @@ The modern definition of neurosecretion has evolved to include the release of an FMA:54559 Bergmann astrocyte Bergmann glial cell of cerebellum + Bergmann glial cell @@ -18199,6 +18360,7 @@ The modern definition of neurosecretion has evolved to include the release of an BTO:0000939 FMA:62516 + basal cell @@ -18366,6 +18528,7 @@ The modern definition of neurosecretion has evolved to include the release of an FMA:69059 prickle cell of epidermis + prickle cell @@ -18396,6 +18559,7 @@ The modern definition of neurosecretion has evolved to include the release of an FMA:70972 MESH:D050527 kidney mesangial cell + Do all of these cells really develop from some mesenchymal stem cell? mesangial cell @@ -18421,6 +18585,7 @@ The modern definition of neurosecretion has evolved to include the release of an A mucus-secreting cell, with numerous apical secretory vesicles containing mucins; nucleus are basally displaced; numerous at the neck of mucus secreting glands neck cell + mucous neck cell @@ -18490,6 +18655,7 @@ The modern definition of neurosecretion has evolved to include the release of an glomerular visceral epithelial cell kidney podocyte renal podocyte + podocyte https://github.com/obophenotype/cell-ontology/issues/1460 @@ -18751,8 +18917,8 @@ The modern definition of neurosecretion has evolved to include the release of an + - https://github.com/obophenotype/cell-ontology/issues/726 obsolete valve cell true @@ -18762,8 +18928,8 @@ The modern definition of neurosecretion has evolved to include the release of an + - https://github.com/obophenotype/cell-ontology/issues/726 obsolete closable valve cell true @@ -18773,8 +18939,8 @@ The modern definition of neurosecretion has evolved to include the release of an + - https://github.com/obophenotype/cell-ontology/issues/726 obsolete permanently open valve cell true @@ -18786,6 +18952,7 @@ The modern definition of neurosecretion has evolved to include the release of an window cell + fenestrated cell @@ -18796,6 +18963,7 @@ The modern definition of neurosecretion has evolved to include the release of an An extracellular matrix secreting cell that secretes collagen. + collagen secreting cell @@ -18843,6 +19011,7 @@ The modern definition of neurosecretion has evolved to include the release of an pericyte cell pericyte of Rouget adventitial cell + Pericytes are CD10-positive, CD13-positive, CD31-negative, CD45-negative, CD106-positive, CD117-negative, CD140-positive, CD144-negative, CD146-positive, CD271-positive, CD325-positive, NG2-positive, RGS5-positive, SMA-positive, and desmin-positive. A subpopulation is CD248-positive. They are also capable of producing angiopoietin 1, CXCL12, TGF-beta, and VEGF-A. pericyte @@ -18892,6 +19061,7 @@ The modern definition of neurosecretion has evolved to include the release of an FMA:70567 gonocyte primitive germ cell + primordial germ cell @@ -19039,6 +19209,7 @@ The modern definition of neurosecretion has evolved to include the release of an Cell of the intestinal epithelium with a brush border made up of many parallel packed microvilli; associated with absorption, particularly of macromolecules. + gut absorptive cell @@ -19078,6 +19249,7 @@ The modern definition of neurosecretion has evolved to include the release of an WBbt:0006829 FBbt:00100291 + glutamatergic neuron @@ -19106,6 +19278,7 @@ The modern definition of neurosecretion has evolved to include the release of an A non-terminally differentiated cell that is capable of developing into a muscle cell. + muscle precursor cell @@ -19129,6 +19302,7 @@ The modern definition of neurosecretion has evolved to include the release of an A cell present in the developing CNS. Functions as both a precursor cell and as a scaffold to support neuronal migration. forebrain radial glial cell + Unlike that of mammals, the brain of adult teleost fish exhibits an intense and widespread neurogenic activity as a result of the persistence of radial glial cells acting as neural progenitors throughout life. radial glial cell @@ -19161,6 +19335,7 @@ radial glial cells acting as neural progenitors throughout life. FMA:62929 M-cell microfold cell + Should double check and see if M cells are particular to a specific region. M cell of gut @@ -19449,6 +19624,7 @@ radial glial cells acting as neural progenitors throughout life. CR cells Horizontal cells of Cajal + While previously called 'pioneer neurons' of the marginal zone, Cajal-Retzius cells are differentiated from pioneer neurons (which are Reln-negative) by their Reln-immunoreactivity. Cajal-Retzius cell @@ -19489,6 +19665,7 @@ radial glial cells acting as neural progenitors throughout life. FMA:62938 FMA:83409 type F enteroendocrine cell + PP cell @@ -19566,6 +19743,7 @@ radial glial cells acting as neural progenitors throughout life. WBbt:0006746 FBbt:00005131 dopaminergic cell + dopaminergic neuron @@ -19631,6 +19809,7 @@ radial glial cells acting as neural progenitors throughout life. A specialized endothelial cell that senses extracellular signals and guides the directed growth of blood vessels. + endothelial tip cell @@ -19679,6 +19858,7 @@ radial glial cells acting as neural progenitors throughout life. choroid plexus cell FMA:70549 epithelial cell of choroid plexus + choroid plexus epithelial cell @@ -19729,6 +19909,7 @@ radial glial cells acting as neural progenitors throughout life. Stromal cell that forms the internal covering of the vertebrate brain and produces ECM for this and the choroid plexus. leptomemingeal cell + leptomeningeal cell @@ -19899,8 +20080,9 @@ radial glial cells acting as neural progenitors throughout life. OBSOLETE. A subset of motor neurons that innervates intrafusal muscle fibers and has small diameter axons. + - Term merged into CL:0008037. Refer to https://github.com/obophenotype/cell-ontology/issues/1364 + Term merged into CL:0008037. obsolete fusimotor neuron true @@ -20074,7 +20256,7 @@ radial glial cells acting as neural progenitors throughout life. - https://github.com/obophenotype/cell-ontology/issues/1930 + Obsoleted as this level of precision is deemed unnecessary for CL. Consider using either the more general CL:0001658 or, if you need to refer to primary pigment cells specifically, a term from a taxon-specific ontology such as FBbt:00004231. obsolete primary pigment cell true @@ -20085,7 +20267,7 @@ radial glial cells acting as neural progenitors throughout life. - https://github.com/obophenotype/cell-ontology/issues/1930 + Obsoleted as this level of precision is deemed unnecessary for CL. Consider using either the more general CL:0001658 or, if you need to refer to secondary pigment cells specifically, a term from a taxon-specific ontology such as FBbt:00004232. obsolete secondary pigment cell true @@ -20096,7 +20278,7 @@ radial glial cells acting as neural progenitors throughout life. - https://github.com/obophenotype/cell-ontology/issues/1930 + Obsoleted as this level of precision is deemed unnecessary for CL. Consider using either the more general CL:0001658 or, if you need to refer to tertiary pigment cells specifically, a term from a taxon-specific ontology such as FBbt:00004233. obsolete tertiary pigment cell true @@ -20137,6 +20319,7 @@ radial glial cells acting as neural progenitors throughout life. A cell of a layer of transitional epithelium in the wall of the proximal urethra, bladder, ureter or renal pelvis, external to the lamina propria. FMA:84127 urinary tract transitional epithelial cell + urothelial cell @@ -20292,6 +20475,7 @@ radial glial cells acting as neural progenitors throughout life. leucocyte white blood cell immune cell + leukocyte @@ -20341,6 +20525,7 @@ radial glial cells acting as neural progenitors throughout life. ganglion cell of retina RGC RGCs + retinal ganglion cell @@ -20466,6 +20651,7 @@ radial glial cells acting as neural progenitors throughout life. horizontal cell HC HCs + retina horizontal cell @@ -20538,6 +20724,7 @@ radial glial cells acting as neural progenitors throughout life. cardiac myocyte cardiomyocyte heart muscle cell + This class encompasses the muscle cells responsible for heart* contraction in both vertebrates and arthropods. The ultrastucture of a wide range of arthropod heart cells has been examined including spiders, horseshoe crabs, crustaceans (see Sherman, 1973 and refs therein) and insects (see Lehmacher et al (2012) and refs therein). According to these refs, the cells participating in heart contraction in all cases are transversely striated. Insects hearts additionally contain ostial cells, also transversely striated muscle cells, but which do not participate in heart contraction. @@ -20627,6 +20814,7 @@ radial glial cells acting as neural progenitors throughout life. BC BCs BPs + retinal bipolar neuron @@ -20669,6 +20857,7 @@ radial glial cells acting as neural progenitors throughout life. A bipolar neuron found in the retina and having connections with photoreceptors cells and neurons in the inner half of the inner plexiform layer. These cells depolarize in response to light stimulation of their corresponding photoreceptors. + ON-bipolar cell @@ -20687,6 +20876,7 @@ radial glial cells acting as neural progenitors throughout life. A bipolar neuron found in the retina and having connections with photoreceptors cells and neurons in the outer half of the inner plexiform layer. These cells depolarize in response to light to dark transition. + OFF-bipolar cell @@ -20730,6 +20920,7 @@ radial glial cells acting as neural progenitors throughout life. A bipolar neuron found in the retina that is synapsed by rod photoreceptor cells but not by cone photoreceptor cells. These neurons depolarize in response to light. FMA:67750 + rod bipolar cell @@ -21146,6 +21337,7 @@ radial glial cells acting as neural progenitors throughout life. BTO:0001441 CALOHA:TS-0647 MESH:D022423 + myeloid cell @@ -21173,6 +21365,7 @@ radial glial cells acting as neural progenitors throughout life. FMA:62845 FMA:83516 erythropoietic cell + Note that in FMA erythropoietic cells are types of nucleated erythrocytes and thus don't include erythrocytes. erythroid lineage cell @@ -21267,6 +21460,7 @@ radial glial cells acting as neural progenitors throughout life. MESH:D004900 normoblast + erythroblast @@ -21302,6 +21496,7 @@ radial glial cells acting as neural progenitors throughout life. A cell of the monocyte, granulocyte, or mast cell lineage. + myeloid leukocyte @@ -21360,6 +21555,7 @@ radial glial cells acting as neural progenitors throughout life. basophilic leucocyte basophilic leukocyte + Matures in the bone marrow and account for <1% of leukocytes in the peripheral blood, spleen, and bone marrow. Basophils are described as being CD11a-positive, CD11b-positive, CD13-positive, CD15-positive, CD18-positive, CD21-positive, CD25-positive, CD29-positive, CD35-positive, CD40-positive, CD40L-positive, CD44-positive, CD45R-negative, CD46-positive, CD49a-positive, CD49b-positive, CD49d-positive, CD55-positive, CD59-positive, CD62L-positive, CD63-positive, CD69-positive, CD90-negative, CD116-positive, CD117-negative, CD124-positive, CD125-positive, CD131-positive, CD161-positive, CD184-positive, CD191-positive, CD192-positive, CD197-positive, CD200R3-positive, CD218-positive, CD282-positive, CD284-positive, CD289-positive, CD290-positive, CD294-positive, natural killer cell receptor 2B4-positive, smad1-positive, CD3-negative, CD4-negative, CD7-negative, CD8-negative, CD14-negative, CD15-negative, CD16-negative, CD19-negative, CD20-negative, CD34-negative, CD36-negative, CD45R-negative, CD56-negative, CD57-negative, CD235a-negative, and GR1-negative. Transcription factors- GATA1-positive, PU.1-positive. basophil @@ -21596,6 +21792,7 @@ radial glial cells acting as neural progenitors throughout life. eosinophilic leucocyte eosinophilic leukocyte + Eosinophils are also CD14-negative, CD32-positive, CD44-positive, CD48-positive, CD69-positive, CD192-negative, MBP1-positive, MBP2-positive, TLR2-negative, TLR4-negative, and lineage-negative (B220, CD2, CD14, CD19, CD56, CD71, CD117, CD123, CD235a (glycophorin A), and TER119). The cytokines IL-3, IL-5, and GM-CSF are involved in their development and differentiation. Usually considered CD16-negative, CD16 is observed on eosinophilic metamyelocyte. eosinophil @@ -21829,6 +22026,7 @@ radial glial cells acting as neural progenitors throughout life. neutrophilic leucocyte neutrophilic leukocyte + neutrophil @@ -21877,6 +22075,7 @@ radial glial cells acting as neural progenitors throughout life. immature neutrophil leucocyte immature neutrophil leukocyte immature neutrophilic leucocyte + immature neutrophil @@ -22133,6 +22332,7 @@ radial glial cells acting as neural progenitors throughout life. BTO:0004721 CD11c+CD123- DC mDC + These cells are CD1a-negative, CD1b-positive, CD11a-positive, CD11c-positive, CD13-positive, CD14-negative, CD20-negative, CD21-negative, CD33-positive, CD40-negative, CD50-positive, CD54-positive, CD58-positive, CD68-negative, CD80-negative, CD83-negative, CD85j-positive, CD86-positive, CD89-negative, CD95-positive, CD120a-negative, CD120b-positive, CD123-negative, CD178-negative, CD206-negative, CD207-negative, CD209-negative, and TNF-alpha-negative. Upon TLR stimulation, they are capable of producing high levels of TNF-alpha, IL-6, CXCL8 (IL-8). myeloid dendritic cell @@ -22222,6 +22422,7 @@ radial glial cells acting as neural progenitors throughout life. plasmacytoid monocyte type 2 DC + plasmacytoid dendritic cell @@ -22283,6 +22484,7 @@ radial glial cells acting as neural progenitors throughout life. mature B lymphocyte mature B-cell mature B-lymphocyte + Mature B cells are also reportedly CD10-negative, CD19-positive, CD22-positive, CD34-negative, CD48-positive, CD79a-positive, CD84-positive, CD127-negative, CD352-positive, RAG-negative, TdT-negative, Vpre-B-negative, and pre-BCR-negative. Transcription factors expressed: Pax5-positive. mature B cell @@ -22356,6 +22558,7 @@ radial glial cells acting as neural progenitors throughout life. effector B cell effector B-cell + Plasma cells develop in the spleen and migrate to the bone marrow. Plasma cells are also reportedly CD5-negative, CD10-negative, CD19-positive, CD20-negative, CD21-negative, CD22-negative, CD23-negative, CD24-negative, CD25-negative, CD27-positive, CD34-negative, CD38-positive, CD40-positive, CD43-positive, CD45-positive, CD48-positive, CD53-low, CD80-negative, CD81-positive, CD86-positive, CD95-positive, CD196-negative, CD229-positive, CD270-positive, CD352-positive, CD361-positive, and IgD-negative. Transcription factors: BLIMP1-positive, IRF4-positive, PAX5-negative, SpiB-negative, Ets1-negative, and XBP1-positive. plasma cell @@ -22416,6 +22619,7 @@ radial glial cells acting as neural progenitors throughout life. memory B lymphocyte memory B-cell memory B-lymphocyte + Memory B-cells are also reportedly CD5-negative, CD10-negative, CD21-positive, CD22-positive, CD23-negative, CD24-positive, CD25-positive, CD27-positive, CD34-negative, CD38-negative, CD40-positive, CD43-negative, CD44-positive, CD45-positive, CD53-positive, CD80-negative, CD81-negative, CD86-positive, and CD196/CCR6-positive. memory B cell @@ -22484,6 +22688,7 @@ radial glial cells acting as neural progenitors throughout life. naive B lymphocyte naive B-cell naive B-lymphocyte + This cell type is compatible with the HIPC Lyoplate markers for 'naive B cell'. Per DSD: Naive B cells are also reportedly CD10-negative, CD19-positive, CD20-positive, CD21-positive, CD22-positive, CD25-negative, CD27-negative, CD34-negative, CD40-positive, CD43-negative, CD45-positive, CD48-positive, CD53-positive, CD80-negative, CD81-positive, CD84-positive, CD86-negative, CD95-negative, CD138-negative, CD150-positive, CD184/CXCR4-positive, CD185/CXCR5-positive, CD196/CCR6-positive, CD200-positive, CD229-positive, CD243-positive, CD289-positive, CD290-positive, CD352-positive, MHCII/HLA-DR-positive, cadherin 9-positive, and sIgH-positive, Transcription factors: Pax5-positive, ETS1-positive, FOXO1A-positive, KLF4-positive, KLF9-positive, MiTF-positive, OBF1-positive, PLZF-positive, and SpiB-positive. naive B cell @@ -22533,6 +22738,7 @@ radial glial cells acting as neural progenitors throughout life. alpha-beta T-cell alpha-beta T-lymphocyte + alpha-beta T cell @@ -22571,6 +22777,7 @@ radial glial cells acting as neural progenitors throughout life. immature alpha-beta T lymphocyte immature alpha-beta T-cell immature alpha-beta T-lymphocyte + immature alpha-beta T cell @@ -22615,6 +22822,7 @@ radial glial cells acting as neural progenitors throughout life. mature alpha-beta T lymphocyte mature alpha-beta T-cell mature alpha-beta T-lymphocyte + mature alpha-beta T cell @@ -22666,6 +22874,7 @@ radial glial cells acting as neural progenitors throughout life. CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte CD4-positive, CD25-positive, alpha-beta regulatory T-cell CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte + This cell type is compatible with the HIPC Lyoplate markers for 'Treg'. The inclusion of CD127lo in the logical definition is compatible with both human and mouse T cells of this subtype. CD4-positive, CD25-positive, alpha-beta regulatory T cell @@ -22797,6 +23006,7 @@ radial glial cells acting as neural progenitors throughout life. CD8-positive, alpha-beta cytotoxic T lymphocyte CD8-positive, alpha-beta cytotoxic T-cell CD8-positive, alpha-beta cytotoxic T-lymphocyte + Note that while T cells of this subset are loosely referred to 'cytotoxic T cells,' as many other T cell types, including CD4-positive, alpha-beta T cells and gamma-delta T cells exhibit cytotoxicity in vitro and in vivo. CD8-positive, alpha-beta cytotoxic T cell @@ -22890,6 +23100,7 @@ radial glial cells acting as neural progenitors throughout life. CD8-positive, alpha-beta intraepithelial T lymphocyte CD8-positive, alpha-beta intraepithelial T-cell CD8-positive, alpha-beta intraepithelial T-lymphocyte + CD8-alpha-beta-positive, alpha-beta intraepithelial T cell @@ -22976,6 +23187,7 @@ radial glial cells acting as neural progenitors throughout life. gammadelta T cell gd T cell + Note that gamma-delta T cells have both thymic and extrathymic differentiation pathways. gamma-delta T cell @@ -23076,6 +23288,7 @@ radial glial cells acting as neural progenitors throughout life. mature gamma-delta T lymphocyte mature gamma-delta T-cell mature gamma-delta T-lymphocyte + mature gamma-delta T cell @@ -23161,6 +23374,7 @@ radial glial cells acting as neural progenitors throughout life. CD8-positive, gamma-delta intraepithelial T lymphocyte CD8-positive, gamma-delta intraepithelial T-cell CD8-positive, gamma-delta intraepithelial T-lymphocyte + CD8-alpha alpha positive, gamma-delta intraepithelial T cell @@ -23408,6 +23622,7 @@ radial glial cells acting as neural progenitors throughout life. TN3 thymocyte double negative 3 preT.DN3.Th + There is growing evidence that molecular markers characterizing double negative thymocytes are different across species, especially in mouse versus human thymus. If in doubt, please consider using CL:0002489 'double negative thymocyte'. DN3 thymocyte @@ -23468,6 +23683,7 @@ radial glial cells acting as neural progenitors throughout life. DN4 immature T-cell T.DN4.th double negative 4 + Note that this type of thymocyte has passed the beta-selection checkpoint and is rapidly proliferating and beginning to rearrange the T cell receptor alpha chain. There is growing evidence that molecular markers characterizing double negative thymocytes are different across species, especially in mouse versus human thymus. If in doubt, please consider using CL:0002489 'double negative thymocyte'. DN4 thymocyte @@ -23518,6 +23734,7 @@ radial glial cells acting as neural progenitors throughout life. DP cell DP thymocyte double-positive, alpha-beta immature T lymphocyte + Thymocytes of this stage are undergoing positive and negative selection. double-positive, alpha-beta thymocyte @@ -23574,6 +23791,7 @@ radial glial cells acting as neural progenitors throughout life. CD4-positive, alpha-beta immature T-cell CD4-positive, alpha-beta immature T-lymphocyte SP CD4 cell + CD4-positive, alpha-beta thymocyte @@ -23629,6 +23847,7 @@ radial glial cells acting as neural progenitors throughout life. CD8-positive, alpha-beta immature T-lymphocyte SP CD8 cell CD8-positive, alpha-beta immature T cell + CD8-positive, alpha-beta thymocyte @@ -23688,6 +23907,7 @@ radial glial cells acting as neural progenitors throughout life. memory T lymphocyte memory T-cell memory T-lymphocyte + memory T cell @@ -23752,6 +23972,7 @@ radial glial cells acting as neural progenitors throughout life. mature natural killer T lymphocyte mature natural killer T-cell mature natural killer T-lymphocyte + mature NK T cell @@ -23799,6 +24020,7 @@ radial glial cells acting as neural progenitors throughout life. regulatory T lymphocyte regulatory T-cell regulatory T-lymphocyte + This cell type may express FoxP3 and CD25 and secretes IL-10 and TGF-beta. regulatory T cell @@ -23859,6 +24081,7 @@ radial glial cells acting as neural progenitors throughout life. immature B-lymphocyte newly formed B cell + Immature B cells are also reportedly CD5-positive, CD10-positive, CD19-positive, CD20-positive, CD21-positive, CD22-positive, CD24-positive, CD25-negative, CD27-negative, CD34-negative, CD38-positive, CD40-positive, CD43-negative, CD45-positive, CD48-positive, CD53-positive, CD79a-positive, CD80-negative, CD81-positive, CD86-negative, CD95-negative, CD127-negative, CD138-negative, CD185-positive, CD196-positive, MHCII/HLA-DR-positive, RAG-positive, TdT-negative, Vpre-B-negative, and preBCR-negative. Transcription factors expressed: Pax5-positive. immature B cell @@ -23910,6 +24133,7 @@ radial glial cells acting as neural progenitors throughout life. BTO:0001133 CALOHA:TS-0819 pre-B cell + precursor B cell @@ -23976,6 +24200,7 @@ radial glial cells acting as neural progenitors throughout life. T1 B cell T2 B cell T3 B cell + This cell type is compatible with the HIPC Lyoplate markers for 'transitional B cell'. transitional stage B cell @@ -24046,6 +24271,7 @@ radial glial cells acting as neural progenitors throughout life. B1 B-cell B1 B-lymphocyte B1 cell + There are small numbers of B-1 cells found in the lymph nodes and spleen, while larger numbers can be found in the peritoneal and pleural cavities. B-1 B cells are reportedly CD11b-positive, CD20-positive, CD21-positive, CD27-positive, CD44-positive, CD45RB-positive, CD48-positive, CD70-negative, CD150-positive, CD244-negative, CD352-positive, sIgM-positive, and sIgD-low. B-1 B cell @@ -24097,6 +24323,7 @@ radial glial cells acting as neural progenitors throughout life. CD5(+) B1 cell CD5+ B1 cell CD5-positive B1 cell + B-1a B cell @@ -24139,6 +24366,7 @@ radial glial cells acting as neural progenitors throughout life. B1b B-cell B1b B-lymphocyte B1b cell + B-1b B cell @@ -24186,6 +24414,7 @@ radial glial cells acting as neural progenitors throughout life. B2 B-lymphocyte B2 cell B-0 B cell + B-2 B cells are reportedly CD48-positive, CD244-negative, and CD352-positive. B-2 B cell @@ -24234,6 +24463,7 @@ radial glial cells acting as neural progenitors throughout life. A natural killer cell that is developmentally immature and expresses natural killer cell receptors (NKR). immature NK cell p-NK + In mouse the NKR are Ly49 molecules and in human these cells express KIR molecules. immature natural killer cell @@ -24429,6 +24659,7 @@ radial glial cells acting as neural progenitors throughout life. progenitor B-cell progenitor B-lymphocyte pre-B cell (Philadelphia nomenclature) + Human pro-B cells are reportedly CD10-positive, CD22-positive, CD34-positive, CD38-positive, CD45-low, CD48-positive, CD79a-positive, CD127-positive, CD184-positive, RAG-positive, TdT-positive, Vpre-B-positive, pre-BCR-negative, IgD-negative, and IgM-negative. Transcription factors expressed: Pax5-positive, EBF-positive, E2A-negative, Ikaros-negative, and PU.1-negative. pro-B cell @@ -24492,6 +24723,7 @@ radial glial cells acting as neural progenitors throughout life. DN1 cell DN1 thymocyte TN1 cell + pro-T cell @@ -24883,6 +25115,7 @@ radial glial cells acting as neural progenitors throughout life. A progenitor cell of the neutrophil lineage. neutrophil stem cell + neutrophil progenitor cell @@ -24913,10 +25146,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - @@ -24925,6 +25154,10 @@ radial glial cells acting as neural progenitors throughout life. + + + + @@ -24969,10 +25202,6 @@ radial glial cells acting as neural progenitors throughout life. - - - - @@ -24993,6 +25222,10 @@ radial glial cells acting as neural progenitors throughout life. + + + + @@ -25015,6 +25248,7 @@ radial glial cells acting as neural progenitors throughout life. CALOHA:TS-0825 FMA:83530 + promyelocyte @@ -25117,6 +25351,7 @@ radial glial cells acting as neural progenitors throughout life. MPP hemopoietic progenitor cell + Markers differ between mouse and human. hematopoietic multipotent progenitor cell @@ -25159,6 +25394,7 @@ radial glial cells acting as neural progenitors throughout life. BTO:0004731 CALOHA:TS-2025 FMA:70338 + Note that this is a class of cell types, not an identified single cell type. lymphoid lineage restricted progenitor cell @@ -25199,6 +25435,7 @@ radial glial cells acting as neural progenitors throughout life. BTO:0004730 CALOHA:TS-2099 FMA:70339 + Note that this is a class of cell types, not an identified single cell type. myeloid lineage restricted progenitor cell @@ -25309,6 +25546,7 @@ radial glial cells acting as neural progenitors throughout life. mature dendritic cell FMA:83038 mature myeloid dendritic cell + mature conventional dendritic cell @@ -25356,6 +25594,7 @@ radial glial cells acting as neural progenitors throughout life. mononuclear leukocyte peripheral blood mononuclear cell + mononuclear cell @@ -25422,6 +25661,7 @@ radial glial cells acting as neural progenitors throughout life. follicular B lymphocyte follicular B-cell follicular B-lymphocyte + Follicular B cells are also reportedly CD48-positive, CD84-positive, CD229-positive, and CD352-positive. follicular B cell @@ -25479,6 +25719,7 @@ radial glial cells acting as neural progenitors throughout life. germinal center B lymphocyte germinal center B-cell germinal center B-lymphocyte + Germinal center B cells are also reportedly CD10-positive, CD19-positive, CD20-positive, CD38-positive, CD44-low, CD45-positive, CD48-positive, CD95-positive, CD352-positive, and HLA-DR-positive. Transcription factors: BCL6-positive, Ets1-positive, IRF8-positive, MTA3-positive, OBF1-positive, PAX5-positive, SpiB-positive, and STAT3-positive. germinal center B cell @@ -25945,6 +26186,7 @@ radial glial cells acting as neural progenitors throughout life. A monocyte that responds rapidly to microbial stimuli by secreting cytokines and antimicrobial factors and which is characterized by high expression of CCR2 in both rodents and humans, negative for the lineage markers CD3, CD19, and CD20, and of larger size than non-classical monocytes. inflammatory monocyte + Markers: CCR2+CXCCR1<low> (human, mouse, rat). classical monocyte @@ -26007,6 +26249,7 @@ radial glial cells acting as neural progenitors throughout life. FMA:84645 free macrophage wandering histiocyte + Markers: CD11b+, CD68+; Mouse: F4/80+; role or process: immune, inflammation (inflammatory response). elicited macrophage @@ -26103,6 +26346,7 @@ radial glial cells acting as neural progenitors throughout life. An elicited macrophage that is recruited into the tissues in response to injury and infection as part of an inflammatory response, expresses high levels of pro-inflammatory cytokines, ROS and NO, and shows potent microbicidal activity. classically activated macrophage M1 macrophage + Markers: Express: TNFa, IL1b, IL6, iNOS, NADPH-oxidase; produce: reactive oxygen species, nitric oxide; role or process: immune, inflammation (inflammatory response). inflammatory macrophage @@ -26150,6 +26394,7 @@ radial glial cells acting as neural progenitors throughout life. FMA:84644 fixed macrophage resting histiocyte + tissue-resident macrophage @@ -26661,6 +26906,7 @@ radial glial cells acting as neural progenitors throughout life. patrolling monocyte resident monocyte + Markers: CCR2-CX3CCR1+ (human, mouse, rat); human: CD16+, CCR5+, CD32/FcgRII-high, MHCII+, CD86+; mouse: CD62L-Ly6C-. non-classical monocyte @@ -26794,6 +27040,7 @@ radial glial cells acting as neural progenitors throughout life. A tissue-resident macrophage found in the central nervous system. CNS macrophage + central nervous system macrophage @@ -27294,6 +27541,7 @@ radial glial cells acting as neural progenitors throughout life. An elicited macrophage characterized by low production of pro-inflammatory and Th1 polarizing cytokines and high expression of arginase-1, and associated with tissue remodelling. M2 macrophage + Role or process: tissue remodeling. alternatively activated macrophage @@ -27393,6 +27641,7 @@ radial glial cells acting as neural progenitors throughout life. MESH:D060168 XAO:0003159 thymic lymphocyte + thymocyte @@ -27458,6 +27707,7 @@ radial glial cells acting as neural progenitors throughout life. DN1 thymocyte double negative 1 preT.DN1.Th + DN1 thymic pro-T cell @@ -27526,6 +27776,7 @@ radial glial cells acting as neural progenitors throughout life. naive thymus-derived CD4-positive, alpha-beta T lymphocyte naive thymus-derived CD4-positive, alpha-beta T-cell naive thymus-derived CD4-positive, alpha-beta T-lymphocyte + These cells have not been exposed to antigen following thymic T-cell selection; found in blood and secondary lymphoid organs. This cell type is compatible with the HIPC Lyoplate markers for 'naive CD4+ T cell', but includes additional markers known to be expressed on naive CD4+ T cells. naive thymus-derived CD4-positive, alpha-beta T cell @@ -27599,6 +27850,7 @@ radial glial cells acting as neural progenitors throughout life. activated CD4-positive, alpha-beta T lymphocyte activated CD4-positive, alpha-beta T-cell activated CD4-positive, alpha-beta T-lymphocyte + activated CD4-positive, alpha-beta T cell @@ -27648,6 +27900,7 @@ radial glial cells acting as neural progenitors throughout life. CD4-positive, alpha-beta memory T-cell CD4-positive, alpha-beta memory T-lymphocyte T4.Mem.Sp + CD4-positive, alpha-beta memory T cell @@ -27701,6 +27954,7 @@ radial glial cells acting as neural progenitors throughout life. naive T lymphocyte naive T-cell naive T-lymphocyte + naive T cell @@ -27768,6 +28022,7 @@ radial glial cells acting as neural progenitors throughout life. Th17 T-lymphocyte Th17 cell helper T cell type 17 + This cell type is compatible with the HIPC Lyoplate markers for 'Th17 CD4+ T cell', but its logical definition includes additional known characteristics of T-helper 17 T cells. T-helper 17 cell @@ -27846,6 +28101,7 @@ radial glial cells acting as neural progenitors throughout life. naive thymus-dervied CD8-positive, alpha-beta T-cell naive thymus-dervied CD8-positive, alpha-beta T-lymphocyte T.8Nve.Sp + This cell traffics in secondary lymphoid organs and blood. This cell type is compatible with the HIPC Lyoplate markers for 'naive CD8+ T cell', but includes additional markers known to be expressed on naive CD8+ T cells. naive thymus-derived CD8-positive, alpha-beta T cell @@ -28015,6 +28271,7 @@ radial glial cells acting as neural progenitors throughout life. natural regulatory T lymphocyte natural regulatory T-cell natural regulatory T-lymphocyte + natural T-regulatory cell @@ -28068,6 +28325,7 @@ radial glial cells acting as neural progenitors throughout life. central memory CD4-positive, alpha-beta T lymphocyte central memory CD4-positive, alpha-beta T-cell central memory CD4-positive, alpha-beta T-lymphocyte + This cell type is compatible with the HIPC Lyoplate markers for 'central memory CD4+ T cell', but includes additional markers known to be expressed on central memory CD4+ T cells. central memory CD4-positive, alpha-beta T cell @@ -28128,6 +28386,7 @@ radial glial cells acting as neural progenitors throughout life. effector memory CD4-positive, alpha-beta T lymphocyte effector memory CD4-positive, alpha-beta T-cell effector memory CD4-positive, alpha-beta T-lymphocyte + This cell type is compatible with the HIPC Lyoplate markers for 'effector memory CD4+ T cell', but includes additional markers known to be expressed on effector memory CD4+ T cells. effector memory CD4-positive, alpha-beta T cell @@ -28198,6 +28457,7 @@ radial glial cells acting as neural progenitors throughout life. activated CD8-positive, alpha-beta T lymphocyte activated CD8-positive, alpha-beta T-cell activated CD8-positive, alpha-beta T-lymphocyte + activated CD8-positive, alpha-beta T cell @@ -28250,6 +28510,7 @@ radial glial cells acting as neural progenitors throughout life. central memory CD8-positive, alpha-beta T lymphocyte central memory CD8-positive, alpha-beta T-cell central memory CD8-positive, alpha-beta T-lymphocyte + This cell type is compatible with the HIPC Lyoplate markers for 'central memory CD8+ T cell', but includes additional markers known to be expressed on central memory CD8+ T cells. central memory CD8-positive, alpha-beta T cell @@ -28324,6 +28585,7 @@ radial glial cells acting as neural progenitors throughout life. CD8-positive, alpha-beta cytokine secreting effector T lymphocyte CD8-positive, alpha-beta cytokine secreting effector T-cell CD8-positive, alpha-beta cytokine secreting effector T-lymphocyte + CD8-positive, alpha-beta cytokine secreting effector T cell @@ -28374,6 +28636,7 @@ radial glial cells acting as neural progenitors throughout life. CD8-positive, alpha-beta memory T-cell CD8-positive, alpha-beta memory T-lymphocyte T.8Mem.Sp + CD8-positive, alpha-beta memory T cell @@ -28410,6 +28673,7 @@ radial glial cells acting as neural progenitors throughout life. cytotoxic T lymphocyte cytotoxic T-cell cytotoxic T-lymphocyte + cytotoxic T cell @@ -28501,6 +28765,7 @@ radial glial cells acting as neural progenitors throughout life. helper T lymphocyte helper T-cell helper T-lymphocyte + helper T cell @@ -28555,6 +28820,7 @@ radial glial cells acting as neural progenitors throughout life. effector memory CD8-positive, alpha-beta T lymphocyte effector memory CD8-positive, alpha-beta T-cell effector memory CD8-positive, alpha-beta T-lymphocyte + This cell type is compatible with the HIPC Lyoplate markers for 'effector memory CD8+ T cell', but includes additional markers known to be expressed on effector memory CD8+ T cells. effector memory CD8-positive, alpha-beta T cell @@ -28611,6 +28877,7 @@ radial glial cells acting as neural progenitors throughout life. immature NK T-cell immature NK T-lymphocyte immature NKT cell + immature NK T cell @@ -28668,6 +28935,7 @@ radial glial cells acting as neural progenitors throughout life. CD8-alpha-alpha-positive, alpha-beta intraepithelial T lymphocyte CD8-alpha-alpha-positive, alpha-beta intraepithelial T-cell CD8-alpha-alpha-positive, alpha-beta intraepithelial T-lymphocyte + CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell @@ -29011,6 +29279,7 @@ radial glial cells acting as neural progenitors throughout life. type I NK T-lymphocyte type I NKT cell invariant NK T cell + In mouse the canonical TCR is V-alpha-14, and in humans it is V-alpha 24. type I NK T cell @@ -29054,6 +29323,7 @@ radial glial cells acting as neural progenitors throughout life. type II NK T-cell type II NK T-lymphocyte type II NKT cell + type II NK T cell @@ -29540,6 +29810,7 @@ radial glial cells acting as neural progenitors throughout life. activated type II NK T-cell activated type II NK T-lymphocyte activated type II NKT cell + activated type II NK T cell @@ -29694,6 +29965,7 @@ radial glial cells acting as neural progenitors throughout life. CD4-positive, alpha-beta cytotoxic T lymphocyte CD4-positive, alpha-beta cytotoxic T-cell CD4-positive, alpha-beta cytotoxic T-lymphocyte + CD4-positive, alpha-beta cytotoxic T cell @@ -29808,6 +30080,7 @@ radial glial cells acting as neural progenitors throughout life. ELP GMLP LMPP + Markers are associated with mouse cells. ELP transcription factors include E2A-positive, Ikaros-positive, EBF-negative, Pax5-negative, PU.1-negative. early lymphoid progenitor @@ -29875,6 +30148,7 @@ radial glial cells acting as neural progenitors throughout life. Cell committed to natural killer cell lineage that has the phenotype CD122-positive, CD34-positive, and CD117-positive. This cell type lacks expression of natural killer receptor proteins. pre-NK cell + These cells are also reportedly CD7-low, CD10-negative, CD45RA-positive, alpha-4-beta-7 integrin-high. pre-natural killer cell @@ -29933,6 +30207,7 @@ radial glial cells acting as neural progenitors throughout life. CD16-negative, CD56-bright NK cell CD56-bright cytokine secreting NK cell CD56-bright cytokine secreting natural killer cell + This cell type is compatible with the HIPC Lyoplate markers for 'CD16-CD56bright NK cell'. Markers are associated with human cell types. CD16-negative, CD56-bright natural killer cell, human @@ -30000,6 +30275,7 @@ radial glial cells acting as neural progenitors throughout life. CD16-positive, CD56-positive natural killer cell cytotoxic CD56-dim NK cell cytotoxic CD56-dim natural killer cell + This cell type is compatible with the HIPC Lyoplate markers for 'CD16+CD56+ NK cell'. Markers are associated with human cell types. CD16-positive, CD56-dim natural killer cell, human @@ -30050,6 +30326,7 @@ radial glial cells acting as neural progenitors throughout life. mucosal invariant T lymphocyte mucosal invariant T-cell mucosal invariant T-lymphocyte + mucosal invariant T cell @@ -30685,6 +30962,7 @@ radial glial cells acting as neural progenitors throughout life. A small pre-B-II cell is a pre-B-II cell that is Rag1-positive, Rag2-positive, pre-BCR-negative, and BCR-negative, is not proliferating, and carries a DNA rearrangement of one or more immunoglobulin light chain genes. small pre-BII cell + Small pre-B-II cells are also reportedly CD10-positive, CD19-positive, CD34-negative, CD79a-positive, CD127-negative, TdT-negative, Vpre-B-negative, sIgM-negative, and sIgD-negative. Transcription factors: PU.1-positive, Ikaros-positive, E2A-positive, and PAX5-positive. small pre-B-II cell @@ -30814,6 +31092,7 @@ radial glial cells acting as neural progenitors throughout life. A pre-B-I cell is a precursor B cell that expresses CD34 and surrogate immunoglobulin light chain (VpreB , Lambda 5 (mouse)/14.1 (human)) on the cell surface, and TdT, Rag1,and Rag2 intracellularly. Cell type carries a D-JH DNA rearrangement, and lacks expression of immunglobulin heavy chain protein. pre-BI cell pro-B cell (Philadelphia nomenclature) + Human pre-B-I cells are reportedly CD10-positive, CD19-positive, CD22-positive, CD38-positive, CD45-low, CD79a-positive, CD127-negative, pre-BCR-negative, IgM-negative, IgD-negative, and Tdt-positive. Transcription factors expressed: Pax5-positive. pre-B-I cell @@ -30871,6 +31150,7 @@ radial glial cells acting as neural progenitors throughout life. A large pre-B-II cell is a pre-B-II cell that is proliferating and is Rag1-negative and Rag2-negative. large pre-B cell large pre-BII cell + Large pre-B-II cells are also reportedly CD10-positive, CD19-positive, CD34-negative, CD79a-positive, CD127-negative, TdT-negative, Vpre-B-positive, pre-BCR-positive, sIgM-negative, and sIgD-negative. Transcription factors: PU.1-positive, Ikaros-positive, E2A-positive, and PAX5-positive. large pre-B-II cell @@ -31682,6 +31962,7 @@ radial glial cells acting as neural progenitors throughout life. unswitched memory B lymphocyte unswitched memory B-cell unswitched memory B-lymphocyte + This cell type is compatible with the HIPC Lyoplate markers for 'IgD+ memory B cell'. Per DSD: Unswitched memory B cells are also reportedly CD48-positive, CD84-positive, CD229-positive, and CD352-positive. unswitched memory B cell @@ -31796,6 +32077,7 @@ radial glial cells acting as neural progenitors throughout life. class switched memory B lymphocyte class switched memory B-cell class switched memory B-lymphocyte + Per DSD: Class switched memory B cells are also reportedly CD48-positive, CD229-positive, and CD352-positive. class switched memory B cell @@ -32101,6 +32383,7 @@ radial glial cells acting as neural progenitors throughout life. memory IgG B lymphocyte memory IgG B-cell memory IgG B-lymphocyte + IgG memory B cell @@ -32162,6 +32445,7 @@ radial glial cells acting as neural progenitors throughout life. CD20-negative B cell FMA:84371 CD27-positive, CD38-positive, CD20-negative B cell + This cell type is compatible with the HIPC Lyoplate markers for 'plasmablast'. Plasmablasts are also reportedly CD48-positive, CD63-positive, CD229-positive, CD270-positive, CD319-positive, CD352-positive, CD361-positive, and IgD-negative. plasmablast @@ -32247,6 +32531,7 @@ radial glial cells acting as neural progenitors throughout life. A plasmablast that secretes IgG. + IgG plasmablast @@ -32315,6 +32600,7 @@ radial glial cells acting as neural progenitors throughout life. A plasmablast that secretes IgA. + IgA plasmablast @@ -32349,6 +32635,7 @@ radial glial cells acting as neural progenitors throughout life. A fully differentiated plasma cell that secretes IgG. + IgG plasma cell @@ -32384,6 +32671,7 @@ radial glial cells acting as neural progenitors throughout life. A fully differentiated plasma cell that secretes IgM. + IgM plasma cell @@ -32419,6 +32707,7 @@ radial glial cells acting as neural progenitors throughout life. A fully differentiated plasma cell that secretes IgA. + IgA plasma cell @@ -32450,6 +32739,7 @@ radial glial cells acting as neural progenitors throughout life. haematopoietic cell haemopoietic cell hemopoietic cell + hematopoietic cell @@ -32537,6 +32827,7 @@ radial glial cells acting as neural progenitors throughout life. dendritic reticular cell type 1 DC + Originally described in the dendritic cell ontology (DC_CL:0000003)(PMID:19243617) These cells are also CD20-negative, MHCII-positive. conventional dendritic cell @@ -34289,6 +34580,7 @@ radial glial cells acting as neural progenitors throughout life. CD133-positive hematopoietic stem cell is a hematopoietic stem cell that is CD34-positive, CD90-positive, and CD133-positive. CALOHA:TS-0448 CD133-positive hematopoietic stem cell + Cell markers are associated with human hematopoietic stem cells. Originally described in the dendritic cell ontology (DC_CL:0000035)(PMID:19243617). CD34-positive, CD38-negative hematopoietic stem cell @@ -34637,6 +34929,7 @@ radial glial cells acting as neural progenitors throughout life. CDP common dendritic precursor pro-DCs + Surface markers are for mouse cells. Originally described in the dendritic cell ontology (DC_CL:0000041) CDP are reportedly CD2-negative, CD3-negative, CD4-negative, CD5-negative, CD8a-negative, CD11c-positive, CD14-negative, CD19-negative, CD20-negative, CD56-negative, B220-negative, Ly6g-negative, MHCII-positive, and Ter119-negative. (PMID:19243617). common dendritic progenitor @@ -34714,6 +35007,7 @@ radial glial cells acting as neural progenitors throughout life. An excitatory granule cell with a soma located in the granular layer of cerebellar cortex. A mature cerebellar granule cell has short dendrites with a characteristic claw-like appearance and a long axon that ascends to the molecular layer where it bifurcates (except in non-teleost fish, where it does not bifurcate) and extends mediolaterally to form parallel fibers. BTO:0004278 granule cell of the cerebellum + It has been noted in at least some mammalian species that granule cells are the most numerous cell type in the cerebellum and in the brain, with at least 99% of all cerebellar neurons being granule cells. cerebellar granule cell @@ -34970,6 +35264,7 @@ radial glial cells acting as neural progenitors throughout life. Th22 T-lymphocyte Th22 cell helper T cell type 22 + TH22 cells are also reportedly CCR4-positive, CCR6-positive, CCR10-positive, CXCR3-negative. TH22 cells are reportedly capable of secreting IL-13. T-helper 22 cell @@ -35014,6 +35309,7 @@ radial glial cells acting as neural progenitors throughout life. activated CD4-positive, alpha-beta T lymphocyte, human activated CD4-positive, alpha-beta T-cell, human activated CD4-positive, alpha-beta T-lymphocyte, human + This cell type is compatible with the HIPC Lyoplate markers for 'activated CD4+ T cell', but includes via logical inference from its parent additional markers known to be expressed on activated CD4+ T cells. The inclusion of HLA-DRA in the definition restricts this definition to human activated CD4+ T cells, as activated mouse T cells do not express MHC class II. activated CD4-positive, alpha-beta T cell, human @@ -35069,6 +35365,7 @@ radial glial cells acting as neural progenitors throughout life. effector CD4-positive, alpha-beta T lymphocyte effector CD4-positive, alpha-beta T-cell effector CD4-positive, alpha-beta T-lymphocyte + This cell type is compatible with the HIPC Lyoplate markers for 'effector CD4+ T cell'. The functional characteristics of this cell type currently undefined in CL, which affects its proper placement within the hierarchy. effector CD4-positive, alpha-beta T cell @@ -35280,6 +35577,7 @@ radial glial cells acting as neural progenitors throughout life. activated CD8-positive, alpha-beta T lymphocyte, human activated CD8-positive, alpha-beta T-cell, human activated CD8-positive, alpha-beta T-lymphocyte, human + This cell type is compatible with the HIPC Lyoplate markers for 'activated CD8+ T cell', but includes via logical inference from its parent additional markers known to be expressed on activated CD8+ T cells. The inclusion of HLA-DRA in the definition restricts this definition to human activated CD8+ T cells, as activated mouse T cells do not express MHC class II. activated CD8-positive, alpha-beta T cell, human @@ -35336,6 +35634,7 @@ radial glial cells acting as neural progenitors throughout life. effector CD8-positive, alpha-beta T lymphocyte effector CD8-positive, alpha-beta T-cell effector CD8-positive, alpha-beta T-lymphocyte + This cell type is compatible with the HIPC Lyoplate markers for 'effector CD8+ T cell'. The functional characteristics of this cell type currently undefined in CL, which affects its proper placement within the hierarchy. effector CD8-positive, alpha-beta T cell @@ -35508,6 +35807,7 @@ radial glial cells acting as neural progenitors throughout life. A monocyte that expresses CD14 and is negative for the lineage markers CD3, CD19, and CD20. monocyte + This cell type is compatible with the HIPC Lyoplate markers for 'monocyte'. Note that while CD14 is considered a reliable marker for human monocytes, it is only expressed on approximately 85% of mouse monocytes. CD14-positive monocyte @@ -35582,6 +35882,7 @@ radial glial cells acting as neural progenitors throughout life. A dendritic cell with the phenotype HLA-DRA-positive. dendritic cell + This cell type is compatible with the HIPC Lyoplate markers for 'dendritic cell'. The inclusion of HLA-DRA in the definition restricts this definition to human dendritic cells. dendritic cell, human @@ -35619,6 +35920,7 @@ radial glial cells acting as neural progenitors throughout life. A myeloid dendritic cell with the phenotype HLA-DRA-positive. myeloid dendritic cell + This cell type is compatible with the HIPC Lyoplate markers for 'myeloid dendritic cell'. The inclusion of HLA-DRA in the definition restricts this definition to human myeloid dendritic cells. myeloid dendritic cell, human @@ -35664,6 +35966,7 @@ radial glial cells acting as neural progenitors throughout life. A plasmacytoid dendritic cell with the phenotype HLA-DRA-positive, CD123-positive, and CD11c-negative. plasmacytoid dendritic cell + This cell type is compatible with the HIPC Lyoplate markers for 'plasmacytoid dendritic cell'. The inclusion of HLA-DRA in the definition restricts this definition to human plasmacytoid dendritic cells. plasmacytoid dendritic cell, human @@ -35900,6 +36203,7 @@ radial glial cells acting as neural progenitors throughout life. 2017-01-30T18:53:32Z https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C12913 + https://github.com/obophenotype/cell-ontology/issues/448 abnormal cell @@ -35957,6 +36261,7 @@ radial glial cells acting as neural progenitors throughout life. TEMRA CD8+ TEMRA CD8-positive TEMRA + This cell type is seen in human but not found in the mouse. effector memory CD8-positive, alpha-beta T cell, terminally differentiated @@ -36013,6 +36318,7 @@ radial glial cells acting as neural progenitors throughout life. https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C12922 tumor cell tumour cell + https://github.com/obophenotype/cell-ontology/issues/448 neoplastic cell @@ -36047,6 +36353,7 @@ radial glial cells acting as neural progenitors throughout life. 2017-01-30T19:39:12Z https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C12917 cancer cell + https://github.com/obophenotype/cell-ontology/issues/448 malignant cell @@ -36092,6 +36399,7 @@ radial glial cells acting as neural progenitors throughout life. 2017-01-30T20:20:48Z + innate lymphoid cell @@ -36178,6 +36486,7 @@ radial glial cells acting as neural progenitors throughout life. burst forming unit erythroid colony forming unit erythroid erythroid stem cell + erythroid progenitor cell, mammalian @@ -36276,6 +36585,7 @@ radial glial cells acting as neural progenitors throughout life. ILC2 natural helper cell nuocyte + group 2 innate lymphoid cell @@ -36345,6 +36655,7 @@ radial glial cells acting as neural progenitors throughout life. 2017-01-31T20:21:26Z ILC3 + group 3 innate lymphoid cell @@ -36480,6 +36791,7 @@ radial glial cells acting as neural progenitors throughout life. An innate lymphoid cell precursor in the human with the phenotype CD34-positive, CD56-positive, CD117-positive.Thie cell type may include precusors to NK cells and ILC3 cells. CD34-positive, CD56-positive, CD117-positive CILP + CD34-positive, CD56-positive, CD117-positive common innate lymphoid precursor, human @@ -36544,6 +36856,7 @@ radial glial cells acting as neural progenitors throughout life. An innate lymphoid cell in the human with the phenotype NKp46-positive that is a precusor for NK cells and ILC3 cells. NKp46-positive ILC + NKp46-positive innate lymphoid cell, human @@ -36581,6 +36894,7 @@ radial glial cells acting as neural progenitors throughout life. An ILC1 cell in the human with the phenotype CD56-negative, IL-7Ralpha-positive, T-bet-positive. innate lymphoid cell 1, human + ILC1, human @@ -36614,6 +36928,7 @@ radial glial cells acting as neural progenitors throughout life. A group 3 innate lymphoid cell in the human with the phenotype IL-7Ralpha-positive. ILC3, human + group 3 innate lymphoid cell, human @@ -36650,6 +36965,7 @@ radial glial cells acting as neural progenitors throughout life. A group 3 innate lymphoid cell in the human with the phenotype IL-7Ralpha-positive, and NKp44-positive. + NKp44-positive group 3 innate lymphoid cell, human @@ -36686,6 +37002,7 @@ radial glial cells acting as neural progenitors throughout life. A group 3 innate lymphoid cell in the human with the phenotype IL-7Ralpha-positive, and NKp44-negative. + NKp44-negative group 3 innate lymphoid cell, human @@ -36735,6 +37052,7 @@ radial glial cells acting as neural progenitors throughout life. A group 2 innate lymphoid cell in the human with the phenotype CD25-positive, CD127-positive, CD161-positive, and GATA-3-positive. ILC2, human + group 2 innate lymphoid cell, human @@ -36764,6 +37082,7 @@ radial glial cells acting as neural progenitors throughout life. An innate lyphoid cell with an immature phenotype. immature ILC + immature innate lymphoid cell @@ -37014,6 +37333,7 @@ radial glial cells acting as neural progenitors throughout life. CD8-positive, alpha-beta memory T lymphocyte, CD45RO-positive CD8-positive, alpha-beta memory T-cell, CD45RO-positive CD8-positive, alpha-beta memory T-lymphocyte, CD45RO-positive + CD8-positive, alpha-beta memory T cell, CD45RO-positive @@ -37661,6 +37981,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-01-19T02:51:58Z MDP + macrophage dendritic cell progenitor @@ -37762,6 +38083,7 @@ radial glial cells acting as neural progenitors throughout life. A lin-negative, MHC-II-negative, CD11c-positive, FLT3-positive cell with intermediate expression of SIRP-alpha. 2010-01-19T03:39:30Z + pre-conventional dendritic cell @@ -38710,6 +39032,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-04-27T12:46:33Z BMCP + There may be an intermediate cell type. These cells also CD13-positive, CD16-positive, CD32-positive, and integrin beta 7-positive. Transcription factors: GATA1-positive, MCP-1-positive, mitf-positive, PU.1-positive, and CEBP/a-low. basophil mast progenitor cell @@ -39257,6 +39580,7 @@ radial glial cells acting as neural progenitors throughout life. follicular T-helper cell follicular helper T cell follicular helper T-cell + T follicular helper cell @@ -39698,6 +40022,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-04-28T10:50:07Z fraction A pre pro B cell + Markers associated with mouse cells. fraction A pre-pro B cell @@ -39770,6 +40095,7 @@ radial glial cells acting as neural progenitors throughout life. A pro-B cell that is CD22-positive, CD34-positive, CD38-positive and TdT-positive (has TdT activity). Pre-BCR is expressed on the cell surface. Cell is CD19-negative, CD20-negative, complement receptor type 2-negative and CD10-low. D-to-J recombination of the heavy chain occurs at this stage. 2010-04-28T11:19:11Z + Markers are commonly associated with human cells. These cells are also reportedly CD21-negative. Transcription factors: PU.1-positive, Ikaros-positive, E2A-positive, and PAX5-positive. early pro-B cell @@ -39880,6 +40206,7 @@ radial glial cells acting as neural progenitors throughout life. A pre-B cell precursor is CD19-low, CD22-positive , CD34-positive, CD38-positive. 2010-04-28T12:06:06Z + Late pro-B cells are also reportedly CD10-positive, CD20-negative, CD21-negative, and TdT-positive. Transcription factors: PU.1-positive, Ikaros-positive, E2A-positive, and PAX5-positive. late pro-B cell @@ -40441,6 +40768,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-06-05T08:25:41Z CD16- monocyte CD16-negative monocyte + This cell type is compatible with the HIPC Lyoplate markers for 'CD16- monocyte'. The markers used in the definition are associated with human monocytes. CD14-positive, CD16-negative classical monocyte @@ -40697,6 +41025,7 @@ radial glial cells acting as neural progenitors throughout life. type 1 pneumocyte type I alveolar cells type I alveolar epithelial cells + type I pneumocyte @@ -40755,6 +41084,7 @@ radial glial cells acting as neural progenitors throughout life. type II alveolar epithelial cell type II alveolocyte lung type II cell + type II pneumocyte @@ -40800,6 +41130,7 @@ radial glial cells acting as neural progenitors throughout life. CALOHA:TS-0737 FMA:63032 acinar cell of pancreas + pancreatic acinar cell @@ -40996,6 +41327,7 @@ radial glial cells acting as neural progenitors throughout life. FMA:66771 columnar cell of the colon vacuolar absorptive cell + enterocyte of epithelium of large intestine @@ -41105,6 +41437,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-06-29T03:22:46Z pulmonary brush cell + brush cell of trachebronchial tree @@ -41230,6 +41563,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-06-30T08:49:43Z FMA:63099 + pancreatic ductal cell @@ -41437,6 +41771,7 @@ radial glial cells acting as neural progenitors throughout life. BTO:0001953 FMA:54560 stretch cell + tanycyte @@ -41530,6 +41865,7 @@ radial glial cells acting as neural progenitors throughout life. FMA:86573 ICC intestinal pacemaker cell + Some argue this cell type is of mesenchymal origin. interstitial cell of Cajal @@ -41739,6 +42075,7 @@ radial glial cells acting as neural progenitors throughout life. BTO:0004850 FMA:83621 MESH:D001854 + MH consider whether bone marrow cells are bone cells in the structural sense vs. being part of bone organ sense. bone marrow cell @@ -41803,6 +42140,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-08-23T11:11:34Z FMA:18709 + interstitial cell of ovary @@ -41892,6 +42230,7 @@ radial glial cells acting as neural progenitors throughout life. FMA:69545 adrenal cortex cell adrenocortical cell + cortical cell of adrenal gland @@ -42667,6 +43006,7 @@ radial glial cells acting as neural progenitors throughout life. IgG-negative class switched memory B lymphocyte IgG-negative class switched memory B-cell IgG-negative class switched memory B-lymphocyte + IgG-negative class switched memory B cell @@ -43194,6 +43534,7 @@ radial glial cells acting as neural progenitors throughout life. atrial myocyte regular atrial cardiac muscle fiber regular cardiac muscle cell of atrium + regular atrial cardiac myocyte @@ -43242,6 +43583,7 @@ radial glial cells acting as neural progenitors throughout life. regular cardiac muscle cell of ventricle regular ventricular cardiac muscle fiber ventricular myocyte + regular ventricular cardiac myocyte @@ -43278,6 +43620,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-08-23T12:10:31Z FMA:72299 ovarian stromal cell + stromal cell of ovary @@ -43446,6 +43789,7 @@ radial glial cells acting as neural progenitors throughout life. FMA:68458 LEC lymphatic endothelial cell + endothelial cell of lymphatic vessel @@ -43477,6 +43821,7 @@ radial glial cells acting as neural progenitors throughout life. FMA:67755 vascular endothelial cell cubodial endothelial cell of vascular tree + These cells are reportedly CD31-positive, CD34-positive, CD144-positive, TAL1-positive. endothelial cell of vascular tree @@ -43619,6 +43964,7 @@ radial glial cells acting as neural progenitors throughout life. BTO:0004956 CALOHA:TS-0112 FMA:67756 + capillary endothelial cell @@ -43654,6 +44000,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-08-24T03:38:29Z FMA:70542 + ciliated columnar cell of tracheobronchial tree @@ -43765,6 +44112,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-08-24T10:45:54Z FMA:256161 + epithelial cell of uterus @@ -43826,6 +44174,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-08-24T03:07:50Z FMA:83534 + late promyelocyte @@ -43907,6 +44256,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-08-24T03:07:53Z FMA:83533 + early promyelocyte @@ -43963,6 +44313,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-08-24T03:33:58Z FMA:86495 + endosteal cell @@ -44545,6 +44896,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-08-25T03:23:22Z FMA:86552 + foveolar cell of stomach @@ -44765,6 +45117,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-08-26T03:12:49Z FMA:70571 + basal cell of epidermis @@ -44804,6 +45157,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-08-26T10:59:44Z BTO:0004632 FMA:70970 + glomerular endothelial cell @@ -44831,6 +45185,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-08-26T03:19:00Z FMA:70543 + granular cell of epidermis @@ -44881,6 +45236,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-08-30T12:54:27Z FMA:83519 + granulocytopoietic cell @@ -44941,6 +45297,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-08-30T01:08:19Z BTO:0000734 FMA:83525 + myelocyte @@ -45193,6 +45550,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-09-02T01:43:55Z type B intercalated cell type B-IC + renal beta-intercalated cell @@ -45272,6 +45630,7 @@ radial glial cells acting as neural progenitors throughout life. brush cell of large intestine tuft cell of epithelium of large intestine tuft cell of large intestine + Brush cells are a distinct cell type from brush border cell-types. brush cell of epithelium proper of large intestine @@ -45314,6 +45673,7 @@ radial glial cells acting as neural progenitors throughout life. fibrillovesicular cell multivesicular cell tuft cell + brush cell @@ -45406,6 +45766,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-09-02T02:38:37Z FMA:263224 + brush cell of trachea @@ -45805,6 +46166,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-09-07T10:45:45Z FMA:63181 + anterior lens cell @@ -45838,6 +46200,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-09-07T10:45:47Z FMA:67559 + lens epithelial cell @@ -45873,6 +46236,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-09-07T10:53:39Z secondary lens fibre + secondary lens fiber @@ -46012,6 +46376,7 @@ radial glial cells acting as neural progenitors throughout life. FMA:256163 FMA:66817 prostate epithelial cell + epithelial cell of prostate @@ -46200,6 +46565,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-09-07T01:59:12Z FMA:74226 + basal epithelial cell of prostatic duct @@ -46375,6 +46741,7 @@ radial glial cells acting as neural progenitors throughout life. FMA:84467 pulmonary myofibroblast pulmonary septal cell + pulmonary interstitial fibroblast @@ -46448,6 +46815,7 @@ radial glial cells acting as neural progenitors throughout life. FMA:70611 smooth muscle fiber of sphincter of pupil smooth muscle fibre of sphincter of pupil + smooth muscle cell of sphincter of pupil @@ -46630,6 +46998,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-09-08T09:21:22Z FMA:63379 stem cell of intestinal crypt of Lieberkuhn + intestinal crypt stem cell @@ -46691,6 +47060,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-09-08T09:28:20Z FMA:63071 + epithelial cell of esophagus @@ -46729,6 +47099,7 @@ radial glial cells acting as neural progenitors throughout life. BTO:0004297 FMA:256157 epithelial cell of colon + epithelial cell of large intestine @@ -46765,6 +47136,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-09-08T09:41:46Z FMA:256159 + epithelial cell of small intestine @@ -46919,6 +47291,7 @@ radial glial cells acting as neural progenitors throughout life. follicular cell of thyroid gland principal cell of thyroid gland thyroid gland follicular cell + thyroid follicular cell @@ -46940,6 +47313,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-09-08T02:14:14Z FMA:87171 totipotent neuroepithelial stem cell + neuroepithelial stem cell @@ -47028,6 +47402,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-09-14T10:57:26Z FMA:63134 + endothelial cell of sinusoid @@ -47203,6 +47578,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-09-10T01:47:45Z FMA:63418 + P/D1 enteroendocrine cell @@ -47378,6 +47754,7 @@ radial glial cells acting as neural progenitors throughout life. PP cell of pancreatic islet PP-cell of pancreatic islet pancreatic polypeptide-secreting cell + The term PP cell of pancreatic acinus was obsoleted due to a lack of evidence, making PP cell of pancreatic islets synonymous with pancreatic PP cell. pancreatic PP cell @@ -47421,6 +47798,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-09-10T03:44:36Z FMA:62937 CCK cell + type I enteroendocrine cell @@ -47448,6 +47826,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-09-10T03:51:47Z FMA:62942 type K enteroendocrine cell + GIP cell @@ -47468,6 +47847,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-09-10T03:59:09Z FMA:62944 + type L enteroendocrine cell @@ -47490,6 +47870,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-09-10T04:08:29Z FMA:62943 N cell + type N enteroendocrine cell @@ -47795,6 +48176,7 @@ radial glial cells acting as neural progenitors throughout life. epithelial reticular cell epithelial reticular cell of thymus thymic epithelial cell + epithelial cell of thymus @@ -48107,6 +48489,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-09-13T04:09:27Z FMA:70606 PE cell + In a consensus model of unidirectional secretion, aqueous humour is formed by transferring solute, principally NaCl, from stroma to posterior chamber, with water passively following the osmotic gradient. Unidirectional secretion comprises three sequential steps. First, NaCl is transferred from the stromal interstitium into the pigmented ciliary epithelial (PE) cells. Second, solute passes from the PE into the non-pigmented ciliary epithelial (NPE) cells through gap junctions. Finally, NPE cells release Na+ and Cl− into the aqueous humour. @@ -48150,6 +48533,7 @@ radial glial cells acting as neural progenitors throughout life. FMA:70607 NPE cell nonpigmented ciliary epithelial cell + In a consensus model of unidirectional secretion, aqueous humour is formed by transferring solute, principally NaCl, from stroma to posterior chamber, with water passively following the osmotic gradient. Unidirectional secretion comprises three sequential steps. First, NaCl is transferred from the stromal interstitium into the pigmented ciliary epithelial (PE) cells. Second, solute passes from the PE into the non-pigmented ciliary epithelial (NPE) cells through gap junctions. Finally, NPE cells release Na+ and Cl− into the aqueous humour. @@ -48257,6 +48641,7 @@ radial glial cells acting as neural progenitors throughout life. FMA:70973 KUPO:0001044 kidney proximal tubule epithelial cell + epithelial cell of proximal tubule @@ -48604,6 +48989,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-09-15T01:34:57Z CALOHA:TS-2040 FMA:70333 + neural cell @@ -48636,6 +49022,7 @@ radial glial cells acting as neural progenitors throughout life. CALOHA:TS-2096 FMA:63875 MESH:D003239 + connective tissue cell @@ -48682,6 +49069,7 @@ radial glial cells acting as neural progenitors throughout life. FMA:82841 MESH:D053595 ESC + This is an in vitro cell type and may be removed in future releases. These cells are reportedly SSEA-4-positive, CD73-negative, and CD324-positive. embryonic stem cell @@ -48757,6 +49145,7 @@ radial glial cells acting as neural progenitors throughout life. FMA:67800 basal cell of lactiferous duct myoepithelial cell of lactiferous gland + myoepithelial cell of mammary gland @@ -48813,6 +49202,7 @@ radial glial cells acting as neural progenitors throughout life. mammary alveolar epithelial cell mammary gland alveolar epithelial cell LMC + lactocyte @@ -48876,6 +49266,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-09-20T01:37:53Z mature luminal cell FMA:73280 + luminal epithelial cell of mammary gland @@ -48914,6 +49305,7 @@ radial glial cells acting as neural progenitors throughout life. BTO:0004300 breast epithelial cell mammary epithelial cell + mammary gland epithelial cell @@ -48950,6 +49342,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-09-20T02:00:00Z BTO:0002922 + bronchial epithelial cell @@ -48969,6 +49362,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-09-20T02:10:36Z + basal epithelial cell of tracheobronchial tree @@ -49029,6 +49423,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-09-20T02:21:12Z + ciliated cell of the bronchus @@ -49145,6 +49540,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-09-20T03:07:03Z bulge keratinocyte + keratinocyte stem cell @@ -49201,6 +49597,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-09-21T10:06:53Z p-NK + Human markers; killer cell immunoglobulin-like receptor 2DL1 is used as a representative example (PRO at this time lacks a KIR superfamily). CD56-positive, CD161-positive immature natural killer cell, human @@ -49262,6 +49659,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-09-20T03:34:05Z + luminal cell of prostate epithelium @@ -49282,6 +49680,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-09-20T03:34:10Z + basal cell of prostate epithelium @@ -49346,6 +49745,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-09-20T04:00:02Z dNK cell decidual NK cell + decidual natural killer cell, human @@ -49668,6 +50068,7 @@ radial glial cells acting as neural progenitors throughout life. FMA:75621 endocardial endothelial cell endothelial cell of endocardium + endocardial cell @@ -49702,6 +50103,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-09-21T04:41:06Z pancreatic endocrine progenitor pancreatic islet progenitor cell + progenitor cell of endocrine pancreas @@ -49919,6 +50321,7 @@ radial glial cells acting as neural progenitors throughout life. primitive erythroblast primitive erythrocyte primitive erythroid cell + primitive red blood cell @@ -50234,6 +50637,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-09-22T01:57:40Z corneal fibroblast corneal keratocyte + keratocyte @@ -50275,6 +50679,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-09-23T03:17:12Z BTO:0004562 cTEC + cortical thymic epithelial cell @@ -50308,6 +50713,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-09-23T03:17:14Z BTO:0004563 mTEC + medullary thymic epithelial cell @@ -50339,6 +50745,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-09-23T03:46:34Z BTO:0004519 myometrium smooth muscle cell + myometrial cell @@ -50408,6 +50815,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-09-23T04:38:49Z BTO:0004533 airway epithelial cell + respiratory epithelial cell @@ -50469,6 +50877,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-09-23T04:42:27Z respiratory mucosa goblet cells + respiratory goblet cell @@ -50491,14 +50900,15 @@ radial glial cells acting as neural progenitors throughout life. OBSOLETE. A cell of an organism that does not pass on its genetic material to the organism's offspring (i.e. a non-germ line cell). + 2010-09-24T09:44:42Z BTO:0001268 FMA:72300 WBbt:0008378 + - https://github.com/obophenotype/cell-ontology/issues/1150 obsolete somatic cell true @@ -50620,6 +51030,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-09-24T02:06:10Z Schwann cell precursor cell + Schwann cell precursor @@ -50673,6 +51084,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-09-24T02:10:31Z Schwann cell ZFA:0001725 + immature Schwann cell @@ -51021,6 +51433,7 @@ radial glial cells acting as neural progenitors throughout life. A monocyte that has characteristics of both patrolling and inflammatory monocytes. 2010-10-04T10:52:03Z + intermediate monocyte @@ -51065,6 +51478,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-10-04T02:38:58Z + Markers are found in human cells. Normally they represent 3-5% of peripheral blood mDCs (human). These cells express high levels of CD283 (TLR3), are capable of producing IL-12p70 and IFN-beta upon stimulation, and inducing a TH1 response [PMCID:PMC2882828]. They are also Necl2-positive. May be human equivalent of murine CD8alpha-positive DCs. CD141-positive myeloid dendritic cell @@ -51178,6 +51592,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-10-04T12:25:42Z non-classical monocyte, human + Markers are associated with human monocytes. CD14-low, CD16-positive monocyte @@ -51221,6 +51636,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-10-04T12:49:47Z CD16+ monocyte + This cell type is compatible with the HIPC Lyoplate markers for 'CD16+ monocyte'. Markers are associated with human cells. Note that this cell type encompasses both human intermediate monocytes (CD14+, CD16-low), and human non-classical monocytes (CD14-low, CD16+). CD14-positive, CD16-positive monocyte @@ -51313,6 +51729,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-10-04T02:39:01Z + Normally represent 10-20% of peripheral blood mDCs (human). They are also CD281-positive (TLR1), CD282-positive (TLR2), CD283-positive (TLR3), CD284-positive (TLR4), CD285-positive (TLR5), CD286-positive (TLR6), CD288-positive (TLR8), and CD290-positive (TLR10) [PMID:20204387]. Upon TLR stimulation, these cells were potent producers of CXCL8 (IL-8), while producing little TNF-alpha. CD1c-positive myeloid dendritic cell @@ -51684,6 +52101,7 @@ radial glial cells acting as neural progenitors throughout life. MESH:D058954 PaSC pancreas stellate cell + pancreatic stellate cell @@ -51888,6 +52306,7 @@ radial glial cells acting as neural progenitors throughout life. CD3e-positive T cell mature T-cell CD3epsilon T cell + mature T cell @@ -51927,6 +52346,7 @@ radial glial cells acting as neural progenitors throughout life. CALOHA:TS-1042 immature T-cell + immature T cell @@ -52006,6 +52426,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-10-15T09:24:08Z CALOHA:TS-0864 FMA:66785 + enucleated reticulocyte @@ -52138,6 +52559,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-10-21T01:16:24Z ETP preT.ETP.Th + ETPs are reportedly CD1a-negative, CD4-negative, CD7-positive, CD8a-negative, CD8b-negative, CD33-low, CD34-high, CD38-low, CD45RA-positive, and CD45RO-negative. early T lineage precursor @@ -53252,6 +53674,7 @@ radial glial cells acting as neural progenitors throughout life. MESH:D000073637 O-2A/OPC O2A/OPC + This cell type can be purified from optic nerves and other regions of the embryonic, postnatal and adult rat CNS and can be differentiated in vitro to oligodendrocytes and type-2 astrocytes. Some references use the terms 'oligodendrocyte precursor cell' and 'oligodendrocyte type-2 astrocyte (O-2A) progenitor' to refer to the same entity (e.g., PMID:10704434), while others describe an oligodendrocyte type-2 astrocyte (O-2A) progenitor cell as the precurosr to oligodendrocyte- and type-2 astrocyte- progenitor cells (e.g, ISBN:9780702028991). oligodendrocyte precursor cell @@ -53461,6 +53884,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-11-22T03:57:57Z + epidermal Langerhans cell @@ -53969,6 +54393,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-11-23T03:30:21Z Mo.6c+II + MHC-II-positive classical monocyte @@ -54395,6 +54820,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-12-03T03:03:02Z MP:0002262 + nasal mucosa goblet cell @@ -54656,6 +55082,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-12-06T02:55:24Z giant trophoblast cell + trophoblast giant cell @@ -54698,6 +55125,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-12-06T03:03:38Z CD4-CD8- T cell double negative T cell + These are precursors to mature T cells; normally, they do not circulate, but are found in the thymus and they have not undergone rearrangement of the alpha and beta T cell receptor genes. double negative thymocyte @@ -54864,6 +55292,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-12-07T09:50:41Z embryonic cardiomyocyte neonatal cardiomyocyte + fetal cardiomyocyte @@ -54902,6 +55331,7 @@ radial glial cells acting as neural progenitors throughout life. IEL intraepithelial T cell intraepithelial T-cell + intraepithelial lymphocyte @@ -55073,6 +55503,7 @@ radial glial cells acting as neural progenitors throughout life. 2010-12-07T04:03:56Z BTO:0002441 FMA:84639 + adventitial cell @@ -55103,6 +55534,7 @@ radial glial cells acting as neural progenitors throughout life. 2011-01-17T03:39:38Z intestinal smooth muscle cell + enteric smooth muscle cell @@ -55603,6 +56035,7 @@ radial glial cells acting as neural progenitors throughout life. 2011-02-08T10:46:34Z KUPO:0001019 + kidney epithelial cell @@ -55687,6 +56120,7 @@ radial glial cells acting as neural progenitors throughout life. 2011-02-21T02:51:22Z subcutaneous fat cell + subcutaneous adipocyte @@ -56411,6 +56845,7 @@ radial glial cells acting as neural progenitors throughout life. 2011-02-28T01:20:20Z small bile duct cholangiocyte + intrahepatic cholangiocyte @@ -56454,6 +56889,7 @@ radial glial cells acting as neural progenitors throughout life. 2011-02-28T01:42:12Z BTO:0004577 + aortic smooth muscle cell @@ -56562,6 +56998,7 @@ radial glial cells acting as neural progenitors throughout life. KUPO:0001099 endothelial cell of vein venous endothelial cell + vein endothelial cell @@ -56589,6 +57026,7 @@ radial glial cells acting as neural progenitors throughout life. 2011-02-28T03:54:42Z BTO:0003245 CALOHA:TS-0047 + aortic endothelial cell @@ -56709,6 +57147,7 @@ radial glial cells acting as neural progenitors throughout life. 2011-02-28T04:57:44Z cardiac fibroblast + fibroblast of cardiac tissue @@ -56872,6 +57311,7 @@ radial glial cells acting as neural progenitors throughout life. 2011-02-28T05:11:03Z BTO:0000764 CALOHA:TS-0575 + fibroblast of lung @@ -56942,6 +57382,7 @@ radial glial cells acting as neural progenitors throughout life. A fibroblast that is part of the mammary gland. 2011-02-28T05:18:38Z + fibroblast of mammary gland @@ -57215,6 +57656,7 @@ radial glial cells acting as neural progenitors throughout life. An epithelial cell of the intestine. 2011-03-01T05:18:31Z + intestinal epithelial cell @@ -57424,6 +57866,7 @@ radial glial cells acting as neural progenitors throughout life. 2011-03-01T09:57:17Z mesenchymal stem cell of adipose + mesenchymal stem cell of adipose tissue @@ -57522,6 +57965,7 @@ radial glial cells acting as neural progenitors throughout life. BTO:0001220 CALOHA:TS-0898 MESH:D012583 + A myelinating Schwann cell wraps around a single axon. Myelination occurs in larger diameter axons, while a process called ensheathment occurs on smaller diameter axons in which a single cell wraps around multiple small, unmyelinated axons separating them with a thin layer of cytoplasm. The structure formed is called a Remak bundle. Schwann cell @@ -57932,6 +58376,7 @@ radial glial cells acting as neural progenitors throughout life. 2011-03-06T03:28:27Z + retinal blood vessel endothelial cell @@ -57978,6 +58423,7 @@ radial glial cells acting as neural progenitors throughout life. 2011-03-06T03:37:09Z BTO:0004910 FMA:75802 + retinal pigment epithelial cell @@ -58126,6 +58572,7 @@ radial glial cells acting as neural progenitors throughout life. 2011-03-06T05:01:28Z BTO:0003336 + smooth muscle cell of the pulmonary artery @@ -58378,6 +58825,7 @@ radial glial cells acting as neural progenitors throughout life. 2011-03-06T05:46:39Z BTO:0004402 + bronchial smooth muscle cell @@ -58443,6 +58891,7 @@ radial glial cells acting as neural progenitors throughout life. A smooth muscle cell of the trachea. 2011-03-06T05:50:28Z + smooth muscle cell of trachea @@ -58478,6 +58927,7 @@ radial glial cells acting as neural progenitors throughout life. A smooth muscle cell of the uterus. 2011-03-06T05:53:28Z + uterine smooth muscle cell @@ -58542,6 +58992,7 @@ radial glial cells acting as neural progenitors throughout life. An astrocyte of the cerebellum. 2011-03-06T06:57:27Z + astrocyte of the cerebellum @@ -58617,6 +59068,7 @@ radial glial cells acting as neural progenitors throughout life. 2011-03-06T06:57:36Z + astrocyte of the cerebral cortex @@ -58677,6 +59129,7 @@ radial glial cells acting as neural progenitors throughout life. A neural crest cell that gives rise to cells of the enteric nervous system. 2011-03-06T07:24:35Z + migratory enteric neural crest cell @@ -58705,6 +59158,7 @@ radial glial cells acting as neural progenitors throughout life. A neuron with a soma found in the hippocampus. 2011-03-06T07:31:49Z + hippocampal neuron @@ -59009,6 +59463,7 @@ radial glial cells acting as neural progenitors throughout life. CALOHA:TS-2377 breast adipocyte fat cell of breast + Adipocytes found in the subcutaneous adipose tissue of breast. The breast consists of three main components, the skin, the subcutaneous adipose tissue and the functional glandular tissue that comprises both parenchyma and stroma.[CALOHA] adipocyte of breast @@ -59105,6 +59560,7 @@ radial glial cells acting as neural progenitors throughout life. 2011-03-14T12:31:49Z BTO:0001255 CALOHA:TS-0935 + skin fibroblast @@ -59163,6 +59619,7 @@ radial glial cells acting as neural progenitors throughout life. 2011-03-14T02:11:10Z BTO:0003972 + prostate stromal cell @@ -59198,6 +59655,7 @@ radial glial cells acting as neural progenitors throughout life. An acinar cell of salivary gland. 2011-03-14T02:22:22Z + acinar cell of salivary gland @@ -59315,6 +59773,7 @@ radial glial cells acting as neural progenitors throughout life. A mature astrocyte that is capable of producing cytokines. activated astrocyte mature astrocytic glia + Mature astrocytes are reportedly able to produce aspartate, ATP, BDNF, BMP-2a, BMP-3, CCL2, CCL3, CCL4, CCL5, CCL19, CCL20,CD40L, CNTF, CTGF, CXCL1, CXCL2, CXCL8, edn-1, aFGF, bFGF, G-CSF, glutamate, GM-CSF, IFN-alpha, IFN-beta, IFN-gamma, IGF-1, IL-1alpha, IL-1beta, IL-2, Il-4, IL-6, IL-10, IL-12, LIF, MIP-2, NGF, nitric oxide, NT3, taurine, TGF-beta, TNF-alpha, TNF-beta. mature astrocyte @@ -59398,6 +59857,7 @@ radial glial cells acting as neural progenitors throughout life. activated microglia mature microglia reactive microglia + Mature microglia are reportedly CCR2-positive, CD4-positive, CD9-positive, CD11a-positive, CD11b-positive, CD11c-positive, CD13-positive, CD16-positive, CDw17-positive, CD18-positive, CD21-positive, CD26-negative, CD32-positive, CD35-positive, CD36-positive, CD40-positive, CD44-positive, CD45-positive, CD53-positive, CD54-positive, CD56-negative, CD58-positive, CD63-positive, CD64-positive, CD66-positive, CD80-positive, CD86-positive, CD87-positive, CD92-positive, CD106-positive, CD107a-positive, CD147-positive, CD155-positive, CD162-positive, CD163-positive, CD171-negative, CD200R-positive, CXCR3-positive, CX3CR1-positive, fibronectin-positive, GD3-positive, GLUT1-positive, GLUT3-negative, GLUT5-positive, MHCI-positive, MHCII-positive, P2X4-positive, RFD7-negative, RGS5-negative, alpha-SMA-negative, vimentin-positive, and vwf-negative. Mature microglia are capable of producing BDNF, CCL3, CCL5, CCL7, CCL8, CCL9, CCL19, CCL20,CD40L, CSF, CXCL1, CXCL2, CXCL4, CXCL5, CXCL8, CXCL9, CXCL10, glutamate, IL-1beta, IL-1ra, IL-3, IL-6, IL-10, IL-12, LT, MMP-2, MMP-9, NGF, nitric oxide, ROS, TGF-beta, TNF-alpha. mature microglial cell @@ -59498,6 +59958,7 @@ radial glial cells acting as neural progenitors throughout life. 2011-06-21T12:29:31Z + epithelial cell of lower respiratory tract @@ -59519,6 +59980,7 @@ radial glial cells acting as neural progenitors throughout life. 2011-06-21T03:11:10Z airway basal cell airway basal stem cell + respiratory basal cell @@ -60073,6 +60535,7 @@ radial glial cells acting as neural progenitors throughout life. 2011-07-08T03:55:57Z FMA:86548 + glandular cell of esophagus @@ -60461,6 +60924,7 @@ radial glial cells acting as neural progenitors throughout life. An endothelial stalk cell is a specialized endothelial cell that follows behind the tip cell of an angiogenic sprout. 2011-08-16T01:49:32Z + endothelial stalk cell @@ -60516,6 +60980,7 @@ radial glial cells acting as neural progenitors throughout life. A skeletal muscle cell that is part of the tongue. 2011-08-16T03:10:02Z + tongue muscle cell @@ -60614,6 +61079,7 @@ radial glial cells acting as neural progenitors throughout life. naive regulatory T lymphocyte naive regulatory T-cell naive regulatory T-lymphocyte + This cell type has been described as CD45RA-negative, but this doesn't fit with our current definition of naive T cell. naive regulatory T cell @@ -60646,6 +61112,7 @@ radial glial cells acting as neural progenitors throughout life. A CD4-positive, CD25-positive alpha-beta regulatory T cell that has encountered antigen. 2011-08-25T03:17:34Z + Cell has been described as being CD45RA-positive in human, but this doesn't fit with our current definition memory T cell. memory regulatory T cell @@ -62304,6 +62771,7 @@ radial glial cells acting as neural progenitors throughout life. short-wavelength-sensitive (S) cone cell CL:0003050 + S cone cell @@ -62965,6 +63433,7 @@ radial glial cells acting as neural progenitors throughout life. https://orcid.org/0000-0002-5260-9315 cell CL:0004219 + A2 amacrine cell @@ -63463,6 +63932,7 @@ radial glial cells acting as neural progenitors throughout life. https://orcid.org/0000-0002-5260-9315 cell CL:0004232 + starburst amacrine cell @@ -64222,6 +64692,7 @@ radial glial cells acting as neural progenitors throughout life. Specialized epithelial cells involved in the maintenance of osmotic homeostasis. They are characterized by abundant mitochondria and ion transporters. In amniotes, they are present in the renal system. In freshwater fish, ionocytes in the skin and gills help maintain osmotic homeostasis by absorbing salt from the external environment. + ionocyte @@ -64301,6 +64772,7 @@ radial glial cells acting as neural progenitors throughout life. A cuboidal epithelial cell of the kidney which regulates sodium and potassium balance. The activity of sodium and potassium channels on the apical membrane of the cell is regulated by aldosterone and vasopressin. In mammals this cell type is located in the renal collecting duct system. + renal principal cell @@ -64327,6 +64799,7 @@ radial glial cells acting as neural progenitors throughout life. A cuboidal epithelial cell of the kidney that regulates acid/base balance. FMA:86560 intercalated cell + Intercalated cells are also called “mitochondria-rich cells”, reflecting the high levels of round mitochondria at their apical pole, or in their cytoplasm, a distribution that is quite different from that of other kidney tubule cells, which accumulated mitochondria around the basolateral membrane. These cells also have numerous irregular apical microvilli compared with the surrounding segment-specific cells. Intercalated cells lack a central cilium, at least in the cortex, which also differentiates them from the adjacent principal cells. renal intercalated cell @@ -64358,6 +64831,7 @@ radial glial cells acting as neural progenitors throughout life. A cuboidal epithelial cell of the kidney which secretes acid and reabsorbs base to regulate acid/base balance. type A intercalated cell type A-IC + Type A intercalated cells are the more abundant type of intercalated cell in the outer stripe of the outer medulla in most mammalian species. renal alpha-intercalated cell @@ -64403,6 +64877,7 @@ radial glial cells acting as neural progenitors throughout life. multiciliated cell multiciliated epithelial cell MCC + multi-ciliated epithelial cell @@ -64557,6 +65032,7 @@ radial glial cells acting as neural progenitors throughout life. Ghrelin secreting cells found in the endocrine pancreas. pancreatic E cell + In mammals the endocrine pancreas is called the Islets of Langerhans. pancreatic epsilon cell @@ -64614,6 +65090,7 @@ radial glial cells acting as neural progenitors throughout life. Mesenchymal derived lymphatic progenitor cells that give rise to the superficial lymphatics. 2012-01-12T05:01:22Z + mesenchymal lymphangioblast @@ -64645,6 +65122,7 @@ radial glial cells acting as neural progenitors throughout life. 2012-01-12T05:21:09Z parachordal lymphangioblast + vascular lymphangioblast @@ -64736,6 +65214,7 @@ radial glial cells acting as neural progenitors throughout life. A motor neuron that synapses to parasympathetic neurons that innervate tear glands, sweat glands, and the smooth muscles and glands of the pulmonary, cardiovascular, and gastrointestinal systems. general visceral motor neuron + Note that these neurons do not synapse directly onto muscles visceromotor neuron @@ -64753,6 +65232,7 @@ radial glial cells acting as neural progenitors throughout life. Multi fate stem cell that gives rise to both hepatocytes and cholangiocytes as descendants. The term often refers to fetal precursors of hepatocytes (differently from 'hepatic stem cell', usually applied to the self-renewing pool of hepatocyte precursors in the adult liver). Hepatoblasts may also be endogenous, as some stem cells found in the liver come from the bone marrow via blood circulation. + hepatoblast https://github.com/obophenotype/cell-ontology/issues/800 @@ -65067,6 +65547,7 @@ radial glial cells acting as neural progenitors throughout life. 2012-06-27T10:57:21Z osteoprogenitor cell + preosteoblast @@ -65108,6 +65589,7 @@ radial glial cells acting as neural progenitors throughout life. Neuron that is part of the enteric nervous system. 2012-06-28T08:20:31Z + enteric neuron @@ -65426,6 +65908,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u Any hematopoietic cell that is a precursor of some other hematopoietic cell type. + hematopoietic precursor cell @@ -65471,6 +65954,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u A transversely striated, synctial cell of skeletal muscle. It is formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. MESH:D018485 + skeletal muscle fiber @@ -65733,6 +66217,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u A skeletal muscle satellite cell that divides by stem cell division. A proportion of this population undergoes symmetric stem cell division, producing two skeletal muscle satellite stem cells. The rest undergo asymmetric stem cell division - retaining their identity while budding off a daughter cell that differentiates into an adult skeletal muscle myoblast. + skeletal muscle satellite stem cell @@ -65805,6 +66290,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u A motor neuron that is capable of directly inhibiting muscle contraction. + In vertebrates, all motor neurons are excitatory, but various types of inhibitory motor neurons exist in invertebrates. inhibitory motor neuron @@ -65916,6 +66402,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u A non-polarised cell precursor cell that is part of some mesenchyme, is associated with the cell matrix but is not connected to other cells and is capable of migration. mesenchyme cell + mesenchymal cell @@ -66018,6 +66505,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u An endocrine cell that is part of the pancreas. + pancreatic endocrine cell @@ -66119,9 +66607,10 @@ Covers cells actively being cultured or stored in a quiescent state for future u + 2017-07-12T11:10:52Z - See https://github.com/obophenotype/cell-ontology/issues/1540. Consider GABAergic neuron or inhibitory interneuron instead. Do note that not all GABAergic neurons are inhibitory (see PMID:12209121) and replacing inhibitory neuron with GABAergic neuron should be done with caution. + Consider GABAergic neuron or inhibitory interneuron instead. Do note that not all GABAergic neurons are inhibitory (see PMID:12209121) and replacing inhibitory neuron with GABAergic neuron should be done with caution. obsolete inhibitory neuron true @@ -66131,9 +66620,10 @@ Covers cells actively being cultured or stored in a quiescent state for future u + 2017-07-12T11:11:06Z - See https://github.com/obophenotype/cell-ontology/issues/1540. Consider using glutamatergic neuron instead. Do note that not all glutamatergic neurons are excitatory and replacing excitatory neuron with glutamatergic neuron should be done with caution. + Consider using glutamatergic neuron instead. Do note that not all glutamatergic neurons are excitatory and replacing excitatory neuron with glutamatergic neuron should be done with caution. obsolete excitatory neuron true @@ -66156,6 +66646,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u An interneuron that has its soma located in the cerebral cortex. cerebral cortex interneuron + cortical interneuron @@ -66262,6 +66753,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u 2020-02-29T17:33:55Z + mural cell @@ -66307,6 +66799,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u EVT extravillous cytotrophloblast + extravillous trophoblast @@ -66630,6 +67123,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u Any cell participating in the inflammatory response to a foreign substance, e.g. neutrophil, macrophage. GOC:pr http://en.wikipedia.org/wiki/Inflammatory_response + inflammatory cell @@ -66708,6 +67202,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u Any cell in a salivary gland. GOC:pr http://en.wikipedia.org/wiki/Salivary_gland + salivary gland cell @@ -66730,6 +67225,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u An enteroendocrine cell that is located in the small intestine. small intestine enteroendocrine cell + enteroendocrine cell of small intestine @@ -66823,6 +67319,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u paneth cell of epithelium of large intestine paneth cell of epithelium of colon paneth-like cell + paneth cell of colon @@ -66854,6 +67351,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u transit-amplifying cell TAC TACs + transit amplifying cell @@ -66902,6 +67400,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u transient amplifying cell of crypt of Lieberkuhn of colon transit amplifying cell of crypt of Lieberkuhn of colon transit-amplifying cell of colon + transit amplifying cell of colon @@ -66943,6 +67442,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u transient amplifying cell of small intestine transit amplifying cell of crypt of Lieberkuhn of small intestine transit-amplifying cell of small intestine + transit amplifying cell of small intestine @@ -67069,6 +67569,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u crypt stem cell of large intestine stem cell of large intestine crypt of Lieberkuhn + intestinal crypt stem cell of large intestine @@ -67101,6 +67602,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u crypt stem cell of small intestine stem cell of small intestine crypt of Lieberkuhn + intestinal crypt stem cell of small intestine @@ -67252,6 +67754,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u A stromal cell found in the lamina propria of the small intestine. + stromal cell of lamina propria of small intestine @@ -67760,6 +68263,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u A macrophage that is located in the colon. macrophage of colon + This is a general grouping term created for use in the EMBL-EBI Single Cell Expression Atlas anatomograms. Please use a more specific cell type term for annotation if possible, given the information available to you. colon macrophage @@ -67790,6 +68294,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u A goblet cell that is located in the colon. goblet cell of colon + colon goblet cell @@ -67848,6 +68353,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u A tuft cell that is a part of the colon. colon tuft cell + tuft cell of colon @@ -67877,6 +68383,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u An enteroendocrine cell that is located in the colon. colon enteroendocrine cell + enteroendocrine cell of colon @@ -67905,6 +68412,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u An intestinal crypt stem cell that is located in the colon. + intestinal crypt stem cell of colon @@ -69223,6 +69731,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u EFO:0010669 lung pericyte cell pulmonary pericyte + lung pericyte @@ -69309,6 +69818,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u 2021-12-13T13:53:01Z EFO:0010708 placental endothelial cell + endothelial cell of placenta @@ -69406,6 +69916,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u 2021-12-13T14:39:25Z EFO:0010711 uterine endothelial cell + endothelial cell of uterus @@ -69530,6 +70041,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u 2022-02-21T16:50:02Z fibro/adipogenic progenitor + fibro/adipogenic progenitor cell @@ -69914,6 +70426,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u 2022-03-24T09:03:44Z lymph node centrocyte + centrocyte @@ -69942,6 +70455,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u 2022-03-24T09:12:41Z lymph node centroblast + centroblast @@ -69970,6 +70484,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u 2022-03-24T09:36:29Z follicular regulatory T cell + T follicular regulatory cell @@ -70062,6 +70577,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u luminal progenitor cell progenitor cell of luminal mammary epithelium + progenitor cell of mammary luminal epithelium @@ -70160,6 +70676,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u MESH:D056809 alveolus of lung epithelial cell + May be merged with pneumocyte in future epithelial cell of alveolus of lung @@ -70268,6 +70785,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u + cardiac endothelial cell @@ -70328,6 +70846,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u A GABAergic interneuron whose soma is located in the cerebral cortex. + cerebral cortex GABAergic interneuron @@ -70360,6 +70879,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u FMA:84104 cortical neuron neuron of cerebral cortex + cerebral cortex neuron https://github.com/obophenotype/cell-ontology/issues/1359 @@ -70499,6 +71019,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u A neuron that has its soma in the heart. + This term is used in 3 GO terms that were created as part of the heart development focus project. cardiac neuron https://github.com/obophenotype/cell-ontology/pull/1488 @@ -70643,6 +71164,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u A vetebrate lens cell that is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye. lens fibre cell + lens fiber cell @@ -70817,6 +71339,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u A cell of the neural crest. Neural crest cells are multipotent. Premigratory neural crest cells are found at the neural plate boarder, some of which will undergo ectomesynchymal transition and delamination to form migratory neural crest cells. + neural crest cell @@ -70983,6 +71506,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u A mesothelial cell that is part of the epicardium. + mesothelial cell of epicardium @@ -70994,6 +71518,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u An undifferentiated cell that originates from a neural stem cell and has the capacity to generate multiple types of lineage-restricted progenitors but not to self-renew. + neural progenitor cell @@ -71097,6 +71622,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u CD4-negative, CD8-negative, alpha-beta regulatory T cells DN Treg double-negative alpha-beta regulatory T cell + double negative T regulatory cell @@ -71115,6 +71641,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u An effector T cell that displays impaired effector functions (e.g., rapid production of effector cytokines, cytotoxicity) and has limited proliferative potential. Tex cell + exhausted T cell @@ -71143,6 +71670,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u A precursor cell that has a tendency to differentiate into a specific type of cell. They are descendants of stem cells, only they are more constrained in their differentiation potential or capacity for self-renewal, and are often more limited in both senses. + progenitor cell @@ -71173,6 +71701,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u Any fibroblast that is part of skeletal muscle tissue. skeleton muscle fibroblast + skeletal muscle fibroblast @@ -71366,6 +71895,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u Cells of the uterine chorion that acquire specialized structural and/or functional features that characterize chorionic trophoblasts. These cells will migrate towards the spongiotrophoblast layer and give rise to syncytiotrophoblasts of the labyrinthine layer. + chorionic trophoblast cell @@ -71400,6 +71930,7 @@ Covers cells actively being cultured or stored in a quiescent state for future u Sympathetic neurons are part of the sympathetic nervous system and are primarily adrenergic producing the neurotransmitter noradrenalin along with other neuropeptides. + sympathetic neuron @@ -71549,6 +72080,7 @@ plexiform layer using GABA. Epithelial cell that is part of the colon epithelium. colonic epithelial cell + colon epithelial cell @@ -71739,6 +72271,7 @@ plexiform layer using GABA. A cell that, by division or terminal differentiation, can give rise to other cell types. + Work is needed on GO 'cell differentiation' before it is clear whether the equivalent class definition 'native cell' that capable_of some 'cell differentiation' works. Also, may want to consider merging this with non-terminally differentiated cell. precursor cell @@ -71828,6 +72361,7 @@ plexiform layer using GABA. + forebrain radial glial cell @@ -71859,6 +72393,7 @@ plexiform layer using GABA. An ionocyte that is part of the lung epithelium. The cells from this type are major sources of the CFTR protein in human and mice. + pulmonary ionocyte @@ -72191,12 +72726,12 @@ plexiform layer using GABA. Nucleus with two or more lobes connected by a thin filament that contains no internal chromatin. + 2009-12-22T03:54:43Z Obsoleted because duplicate with GO term. obsolete lobed nucleus - https://github.com/obophenotype/cell-ontology/issues/734 true @@ -72297,27 +72832,19 @@ plexiform layer using GABA. - - - - - - - - - - - - - A nucleus size quality which is relatively high compared to the amount of cytoplasm present in the same cell. + OBSOLETE. A nucleus size quality which is relatively high compared to the amount of cytoplasm present in the same cell. + + 2009-12-23T10:53:24Z - increased nucleus size + This class was a phenotype, not a cell type. + obsolete increased nucleus size + true - A nucleus size quality which is relatively high compared to the amount of cytoplasm present in the same cell. + OBSOLETE. A nucleus size quality which is relatively high compared to the amount of cytoplasm present in the same cell. GOC:tfm @@ -72427,6 +72954,7 @@ plexiform layer using GABA. 2020-05-07T16:03:27Z serous cell of tracheobronchial tree + tracheobronchial serous cell @@ -72478,6 +73006,7 @@ plexiform layer using GABA. 2020-05-07T18:14:52Z goblet cell of tracheobronchial tree + tracheobronchial goblet cell @@ -72609,6 +73138,7 @@ plexiform layer using GABA. 2020-07-21T12:50:22Z smooth muscle cell of tracheobronchial tree + tracheobronchial smooth muscle cell @@ -72676,6 +73206,7 @@ plexiform layer using GABA. EFO:0010705 periportal LSEC periportal hepatic sinusoidal endothelial cell + endothelial cell of periportal hepatic sinusoid @@ -72719,6 +73250,7 @@ plexiform layer using GABA. EFO:0010706 central venous hepatic sinusoidal endothelial cell pericentral LSEC + endothelial cell of pericentral hepatic sinusoid @@ -72761,6 +73293,7 @@ plexiform layer using GABA. 2020-10-12T10:29:31Z periportal hepatocyte + periportal region hepatocyte @@ -72798,6 +73331,7 @@ plexiform layer using GABA. 2020-10-12T10:57:40Z midzonal hepatocyte + midzonal region hepatocyte @@ -72835,6 +73369,7 @@ plexiform layer using GABA. 2020-10-12T11:03:51Z centrilobular hepatocyte + centrilobular region hepatocyte @@ -72871,6 +73406,7 @@ plexiform layer using GABA. 2020-10-14T14:59:07Z intestinal goblet cell + intestine goblet cell @@ -72908,6 +73444,7 @@ plexiform layer using GABA. 2020-10-15T12:47:46Z intestinal brush cell + intestinal tuft cell @@ -73145,6 +73682,7 @@ plexiform layer using GABA. + lung goblet cell @@ -73166,6 +73704,7 @@ plexiform layer using GABA. A cell that is part of a cardiac valve. heart valve cell + cardiac valve cell @@ -73329,6 +73868,7 @@ plexiform layer using GABA. pulmonary neuroendocrine cell PNEC + lung neuroendocrine cell @@ -73429,6 +73969,7 @@ plexiform layer using GABA. + lung ciliated cell @@ -73449,6 +73990,7 @@ plexiform layer using GABA. + lung secretory cell @@ -73482,6 +74024,7 @@ plexiform layer using GABA. A smooth muscle cell that is part of the small intestine. FMA:15050 non-striated muscle fiber of small intestine + smooth muscle cell of small intestine @@ -73605,6 +74148,7 @@ plexiform layer using GABA. A smooth muscle cell that is part of the ileum. FMA:15066 non-striated muscle fiber of ileum + smooth muscle fiber of ileum @@ -73647,6 +74191,7 @@ plexiform layer using GABA. FMA:15653 non-striated muscle fiber of large intestine + smooth muscle cell of large intestine @@ -74101,6 +74646,7 @@ plexiform layer using GABA. An epithelial cell that is part of the urethra. FMA:256165 + epithelial cell of urethra @@ -74169,6 +74715,7 @@ plexiform layer using GABA. A fibroblast that is part of the connective tissue of prostate. FMA:261271 + fibroblast of connective tissue of prostate @@ -74315,6 +74862,7 @@ plexiform layer using GABA. A fibroblast that is part of the connective tissue of nonglandular part of prostate. FMA:261281 + fibroblast of connective tissue of nonglandular part of prostate @@ -74338,6 +74886,7 @@ plexiform layer using GABA. A fibroblast that is part of the connective tissue of glandular part of prostate. FMA:261283 + fibroblast of connective tissue of glandular part of prostate @@ -74468,6 +75017,7 @@ plexiform layer using GABA. FMA:261293 adipocyte of epicardial fat epicardial fat cell + epicardial adipocyte @@ -74571,6 +75121,7 @@ plexiform layer using GABA. FMA:261300 epicardial adipocyte of left ventricle epicardial fat cell of left ventricle + adipocyte of epicardial fat of left ventricle @@ -74623,6 +75174,7 @@ plexiform layer using GABA. A goblet cell that is part of the epithelium of bronchus. FMA:263032 goblet cell of epithelium of bronchus + bronchial goblet cell @@ -74862,6 +75414,7 @@ plexiform layer using GABA. A goblet cell that is part of the epithelium of large intestine. FMA:263054 goblet cell of epithelium of large intestine + large intestine goblet cell @@ -75140,6 +75693,7 @@ plexiform layer using GABA. A goblet cell that is part of the epithelium proper of ileum. FMA:263067 goblet cell of epithelium proper of ileum + ileal goblet cell @@ -75236,6 +75790,7 @@ plexiform layer using GABA. FMA:263075 goblet cell of epithelium of trachea + tracheal goblet cell @@ -75271,6 +75826,7 @@ plexiform layer using GABA. A serous secreting cell that is part of the epithelium of trachea. FMA:263078 + serous cell of epithelium of trachea @@ -75300,6 +75856,7 @@ plexiform layer using GABA. A serous secreting cell that is part of the epithelium of bronchus. FMA:263080 + serous cell of epithelium of bronchus @@ -75383,6 +75940,7 @@ plexiform layer using GABA. An enterocyte that is part of the epithelium of small intestine. FMA:263086 + enterocyte of epithelium of small intestine @@ -75563,6 +76121,7 @@ plexiform layer using GABA. An enterocyte that is part of the epithelium proper of ileum. FMA:263102 + enterocyte of epithelium proper of ileum @@ -75592,6 +76151,7 @@ plexiform layer using GABA. A paneth cell that is part of the epithelium of small intestine. FMA:263104 + paneth cell of epithelium of small intestine @@ -75694,6 +76254,7 @@ plexiform layer using GABA. A columnar cell of the colon that is part of the colonic epithelium. FMA:263114 vacuolar absorptive cell of epithelium of colon + enterocyte of colon @@ -75729,6 +76290,7 @@ plexiform layer using GABA. A basal cell that is part of the epithelium of trachea. FMA:263118 + basal cell of epithelium of trachea @@ -75909,6 +76471,7 @@ plexiform layer using GABA. A M cell that is part of the epithelium of small intestine. FMA:263128 + microfold cell of epithelium of small intestine @@ -76987,6 +77550,7 @@ plexiform layer using GABA. LSEC endotheliocyte of hepatic sinusoid liver sinusoidal endothelial cell + endothelial cell of hepatic sinusoid @@ -77369,6 +77933,7 @@ plexiform layer using GABA. FMA:67761 KUPO:0001095 arterial endothelial cell + endothelial cell of artery @@ -77399,6 +77964,7 @@ plexiform layer using GABA. An endothelial cell that is part of the venule. FMA:67762 + endothelial cell of venule @@ -77798,6 +78364,7 @@ plexiform layer using GABA. A somatic stem cell that is part of the epidermis. FMA:70541 epidermal stem cell + stem cell of epidermis @@ -77869,6 +78436,7 @@ plexiform layer using GABA. An epithelial cell that is part of the conjunctiva. FMA:70552 epithelial cell of conjunctiva + conjunctival epithelial cell @@ -77999,6 +78567,7 @@ plexiform layer using GABA. An epithelial cell that is part of the lacrimal sac. FMA:70560 + epithelial cell of lacrimal sac @@ -78160,6 +78729,7 @@ plexiform layer using GABA. A smooth muscle cell that is part of the ciliary body. FMA:70610 smooth muscle cell of ciliary body + ciliary muscle cell @@ -78273,6 +78843,7 @@ plexiform layer using GABA. A basal cell that is part of the epithelium of esophagus. FMA:70731 basal cell of esophageal epithelium + epithelial cell of stratum germinativum of esophagus @@ -78312,6 +78883,7 @@ plexiform layer using GABA. An epithelial cell that is part of the sweat gland. FMA:70952 + epithelial cell of sweat gland @@ -78339,6 +78911,7 @@ plexiform layer using GABA. An epithelial cell that is part of the nephron. FMA:70965 + epithelial cell of nephron @@ -78371,6 +78944,7 @@ plexiform layer using GABA. KUPO:0001034 Bowmans capsule epithelial cell epithelial cell of Bowman's capsule + epithelial cell of glomerular capsule @@ -78425,6 +78999,7 @@ plexiform layer using GABA. FMA:70968 KUPO:0001035 epithelial cell of parietal layer of glomerular capsule + parietal epithelial cell @@ -78498,6 +79073,7 @@ plexiform layer using GABA. FMA:70982 KUPO:0001059 epithelial cell of renal collecting tubule + kidney collecting duct epithelial cell @@ -78611,6 +79187,7 @@ plexiform layer using GABA. CALOHA:TS-2374 FMA:72144 skin melanocyte + melanocyte of skin @@ -79271,6 +79848,7 @@ plexiform layer using GABA. FMA:84583 smooth muscle fiber of prostate + smooth muscle cell of prostate @@ -79339,6 +79917,7 @@ plexiform layer using GABA. An epithelial cell that is part of the bile duct. Cholangiocytes contribute to bile secretion via net release of bicarbonate and water. They are cuboidal epithelium in the small interlobular bile ducts, but become columnar and mucus secreting in larger bile ducts approaching the porta hepatis and the extrahepatic ducts. FMA:86481 epithelial cell of bile duct + cholangiocyte @@ -79445,6 +80024,7 @@ plexiform layer using GABA. A mesothelial cell that is part of the pleura. FMA:86737 pleural mesothelial cell + mesothelial cell of pleura @@ -79506,6 +80086,7 @@ plexiform layer using GABA. A mesothelial cell that is part of the visceral pleura. FMA:86739 + mesothelial cell of visceral pleura @@ -79536,6 +80117,7 @@ plexiform layer using GABA. FMA:86785 KUPO:0001022 kidney tubule epithelial cell + This needs to be further defined as a juxtamedullary nephron. Will request the juxtamedullary nephron tubule class from UBERON. nephron tubule epithelial cell @@ -79573,6 +80155,7 @@ plexiform layer using GABA. goblet cell of epithelium of small intestine goblet cell of small intestine small intestinal goblet cell + small intestine goblet cell @@ -79606,6 +80189,7 @@ plexiform layer using GABA. A cell that is part of a kidney. KUPO:0001010 + kidney cell @@ -79627,6 +80211,7 @@ plexiform layer using GABA. A cell that is part of kidney interstitium. KUPO:0001013 + kidney interstitial cell @@ -79720,6 +80305,7 @@ plexiform layer using GABA. KUPO:0001023 + kidney glomerular epithelial cell @@ -79909,6 +80495,7 @@ plexiform layer using GABA. A cell that is part of a tip of a renal papilla. KUPO:0001112 + papillary tips cell @@ -80052,6 +80639,7 @@ plexiform layer using GABA. KUPO:0001024 + kidney cortex tubule cell @@ -80273,6 +80861,7 @@ plexiform layer using GABA. KUPO:0001102 + kidney interstitial fibroblast @@ -80332,6 +80921,7 @@ plexiform layer using GABA. A tissue-resident macrophage that is part of some kidney. KUPO:0001109 + kidney resident macrophage @@ -80412,6 +81002,7 @@ plexiform layer using GABA. KUPO:0001114 + kidney pelvis urothelial cell @@ -80974,6 +81565,7 @@ plexiform layer using GABA. KUPO:0001058 + kidney connecting tubule epithelial cell @@ -81090,6 +81682,7 @@ plexiform layer using GABA. KUPO:0001045 + kidney proximal convoluted tubule epithelial cell @@ -81131,6 +81724,7 @@ plexiform layer using GABA. KUPO:0001046 + kidney proximal straight tubule epithelial cell @@ -81177,6 +81771,7 @@ plexiform layer using GABA. KUPO:0001056 + kidney distal convoluted tubule epithelial cell @@ -81215,6 +81810,7 @@ plexiform layer using GABA. KUPO:0001057 + macula densa epithelial cell @@ -81330,6 +81926,7 @@ plexiform layer using GABA. KUPO:0001030 + kidney capillary endothelial cell @@ -81402,6 +81999,7 @@ plexiform layer using GABA. KUPO:0001047 + kidney loop of Henle epithelial cell @@ -81477,6 +82075,7 @@ plexiform layer using GABA. KUPO:0001037 + glomerular capillary endothelial cell @@ -81597,6 +82196,7 @@ plexiform layer using GABA. KUPO:0001048 + kidney loop of Henle ascending limb epithelial cell @@ -81673,6 +82273,7 @@ plexiform layer using GABA. An endothelial cell that is part of some peritubular capillary. KUPO:0001065 + peritubular capillary endothelial cell @@ -81748,6 +82349,7 @@ plexiform layer using GABA. KUPO:0001077 + kidney cortex artery cell @@ -81860,6 +82462,7 @@ plexiform layer using GABA. KUPO:0001039 + kidney afferent arteriole endothelial cell @@ -81926,6 +82529,7 @@ plexiform layer using GABA. KUPO:0001042 + kidney efferent arteriole endothelial cell @@ -81999,6 +82603,7 @@ plexiform layer using GABA. An epithelial cell that is part of some loop of Henle thick ascending limb. It is known in some mammalian species that this cell may express the Na+-K+-2Cl− cotransporter (NKCC2) apically. KUPO:0001049 + kidney loop of Henle thick ascending limb epithelial cell @@ -82047,6 +82652,7 @@ plexiform layer using GABA. An epithelial cell that is part of some loop of Henle thin ascending limb. KUPO:0001050 + kidney loop of Henle thin ascending limb epithelial cell @@ -82084,6 +82690,7 @@ plexiform layer using GABA. An epithelial cell that is part of some loop of Henle thick ascending limb segment located in the renal medulla. KUPO:0001051 + kidney loop of Henle medullary thick ascending limb epithelial cell @@ -82127,6 +82734,7 @@ plexiform layer using GABA. An epithelial cell that is part of some loop of Henle thick ascending limb segment located in the renal cortex. KUPO:0001052 + kidney loop of Henle cortical thick ascending limb epithelial cell @@ -82170,6 +82778,7 @@ plexiform layer using GABA. An epithelial cell that is part of some loop of Henle thin descending limb. KUPO:0001054 + kidney loop of Henle thin descending limb epithelial cell @@ -82366,6 +82975,7 @@ plexiform layer using GABA. A cell that is part of some vasa recta ascending limb. KUPO:0001074 + It is known in some mammalian species that this cell may express PV-1, a component of the fenestral diaphragm. vasa recta ascending limb cell @@ -82836,6 +83446,7 @@ plexiform layer using GABA. A cell that is part of a collecting duct of renal tubule. KUPO:0001012 Wikipedia:Kidney_collecting_duct_cell + kidney collecting duct cell @@ -82865,6 +83476,7 @@ plexiform layer using GABA. A cell that is part of some vasa recta descending limb. KUPO:0001071 + It is known in some mammalian species that this cell may express the urea transporter B. vasa recta descending limb cell @@ -82984,6 +83596,7 @@ plexiform layer using GABA. A pericyte cell located in the kidney interstitium. KUPO:0001104 + renal interstitial pericyte @@ -83018,6 +83631,7 @@ plexiform layer using GABA. KUPO:0001120 + bladder cell @@ -83070,6 +83684,7 @@ plexiform layer using GABA. NCIT:C32210 bladder transitional cell transitional epithelial cell of urinary bladder + bladder urothelial cell @@ -83105,6 +83720,7 @@ plexiform layer using GABA. KUPO:0001124 + urethra urothelial cell @@ -83146,6 +83762,7 @@ plexiform layer using GABA. KUPO:0001128 + kidney collecting duct principal cell @@ -83183,6 +83800,7 @@ plexiform layer using GABA. KUPO:0001129 http://en.wikipedia.org/wiki/Collecting_duct_system#Intercalated_cells + kidney collecting duct intercalated cell @@ -83213,6 +83831,7 @@ plexiform layer using GABA. FMA:70986 exocrine pancreas cell + epithelial cell of exocrine pancreas @@ -83406,6 +84025,7 @@ plexiform layer using GABA. gamma-aminobutyric acid ergic spiny projection neuron striatal medium spiny neuron medium-sized densely spiny neuron + medium spiny neuron @@ -83560,6 +84180,7 @@ plexiform layer using GABA. The various hormone- or neurotransmitter-secreting cells present throughout the mucosa of the intestinal tract. + intestinal enteroendocrine cell @@ -83631,10 +84252,10 @@ plexiform layer using GABA. OBSOLETE. A respiratory stem cell found at the junction of the terminal (conductive) bronchiole and the respiratory bronchiole, which gives rise to alveolar cell types and club cells in response to lung injury. + Duplicated term - merged into CL:0002638 obsolete bronchioalveolar stem cells - https://github.com/obophenotype/cell-ontology/issues/1443 true @@ -83696,6 +84317,7 @@ plexiform layer using GABA. BTO:0001141 PAEC cell + pulmonary artery endothelial cell @@ -84549,6 +85171,7 @@ plexiform layer using GABA. Glandular cell of duodenal epithelium. Example: Enterocytes, Goblet cells, enteroendocrine cells; Paneth cells; M cells; Brunner's gland cell. CALOHA:TS-1275 duodenum glandular cells + duodenum glandular cell @@ -84881,6 +85504,7 @@ plexiform layer using GABA. Glandular cell of seminal vesicle epithelium. CALOHA:TS-1283 seminal vesicle glandular cells + seminal vesicle glandular cell @@ -85077,6 +85701,7 @@ plexiform layer using GABA. CALOHA:TS-2372 cerebral cortex endothelial cells endothelial cells of cerebral cortex + cerebral cortex endothelial cell @@ -85117,6 +85742,7 @@ plexiform layer using GABA. Circulating macrophages and tissue macrophages (alveolar macrophages) of lung. CALOHA:TS-0576 lung macrophages + lung macrophage @@ -85376,6 +86002,7 @@ plexiform layer using GABA. 2014-02-11T17:29:04Z CL:2000001 + peripheral blood mononuclear cell @@ -85411,6 +86038,7 @@ plexiform layer using GABA. decidua cell decidual stromal cell CL:2000002 + decidual cell @@ -85459,6 +86087,7 @@ plexiform layer using GABA. 2014-03-26T22:14:56Z CL:2000004 + pituitary gland cell @@ -85517,6 +86146,7 @@ plexiform layer using GABA. 2014-03-28T21:35:33Z CL:2000006 + tonsil germinal center B cell @@ -85799,6 +86429,7 @@ plexiform layer using GABA. 2014-06-04T16:00:56Z CL:2000016 + lung microvascular endothelial cell @@ -85857,6 +86488,7 @@ plexiform layer using GABA. 2014-06-04T17:08:47Z CL:2000018 + endothelial cell of coronary artery @@ -85945,6 +86577,7 @@ plexiform layer using GABA. 2014-06-24T23:17:00Z CL:2000021 + sebaceous gland cell @@ -86257,6 +86890,7 @@ plexiform layer using GABA. PNS neuron peripheral neuron CL:2000032 + peripheral nervous system neuron @@ -86523,6 +87157,7 @@ plexiform layer using GABA. 2014-07-09T00:09:54Z CL:2000041 + dermis microvascular lymphatic vessel endothelial cell @@ -86552,6 +87187,7 @@ plexiform layer using GABA. 2014-07-09T00:12:00Z CL:2000042 + embryonic fibroblast @@ -86581,6 +87217,7 @@ plexiform layer using GABA. 2014-07-09T00:18:22Z CL:2000043 + brain pericyte @@ -86668,6 +87305,7 @@ plexiform layer using GABA. 2014-08-12T20:50:28Z CL:2000046 + ventricular cardiac muscle cell @@ -86923,6 +87561,7 @@ plexiform layer using GABA. 2014-10-06T19:16:11Z hepatic dendritic cell CL:2000055 + http://www.jleukbio.org/content/66/2/322.abstract liver dendritic cell @@ -87038,6 +87677,7 @@ plexiform layer using GABA. 2014-10-07T17:46:27Z CL:2000059 + http://www.sciencellonline.com/site/productInformation.php?keyword=4400 prostate gland microvascular endothelial cell @@ -87072,6 +87712,7 @@ plexiform layer using GABA. vCTB villous cytotrophoblast CL:2000060 + Same as synctial trophoblast? placental villous trophoblast http://www.sciencellonline.com/site/productInformation.php?keyword=7120 @@ -87201,6 +87842,7 @@ plexiform layer using GABA. 2014-10-07T17:59:13Z CL:2000064 + http://www.sciencellonline.com/site/productInformation.php?keyword=7310 ovarian surface epithelial cell @@ -88046,6 +88688,7 @@ plexiform layer using GABA. 2015-03-31T21:07:02Z CL:2000092 + hair follicular keratinocyte @@ -88075,6 +88718,7 @@ plexiform layer using GABA. 2015-03-31T21:16:22Z CL:2000093 + bronchus fibroblast of lung @@ -88133,6 +88777,7 @@ plexiform layer using GABA. 2015-05-26T18:58:34Z CL:2000095 + cord blood hematopoietic stem cell @@ -88248,6 +88893,7 @@ plexiform layer using GABA. 2019-02-18T19:41:20Z HBC CL:3000001 + Hofbauer cells are a heterogenic group of macrophages that resemble M2-like cells. Initially described in chorionic villi in humans, a Hofbauer cell is now often used to describe any fetal-derived placental macrophage that resides within the placental villous core, amnion, and chorion laeve. Hofbauer cell @@ -88386,6 +89032,7 @@ plexiform layer using GABA. A fibroblast that is part of the breast. breast fibroblast + fibroblast of breast @@ -88762,6 +89409,7 @@ plexiform layer using GABA. ILX:0770149 + lamp5 GABAergic cortical interneuron @@ -88798,6 +89446,7 @@ plexiform layer using GABA. ILX:0770103 NP neuron + near-projecting glutamatergic cortical neuron @@ -88834,6 +89483,7 @@ plexiform layer using GABA. CT projecting neuron + corticothalamic-projecting glutamatergic cortical neuron @@ -88918,6 +89568,7 @@ plexiform layer using GABA. ILX:0770150 + sncg GABAergic cortical interneuron @@ -88956,6 +89607,7 @@ plexiform layer using GABA. ILX:0770151 + vip GABAergic cortical interneuron @@ -88994,6 +89646,7 @@ plexiform layer using GABA. ILX:0770152 + sst GABAergic cortical interneuron @@ -89032,6 +89685,7 @@ plexiform layer using GABA. ILX:0770154 + pvalb GABAergic cortical interneuron @@ -89619,6 +90273,7 @@ plexiform layer using GABA. + A retinal ganglion cell that is depolarized by illumination of its receptive field center. ON retinal ganglion cell @@ -89637,6 +90292,7 @@ plexiform layer using GABA. A retinal ganglion cell that is depolarized by decreased illumination of their receptive field center. + OFF retinal ganglion cell @@ -89652,10 +90308,11 @@ plexiform layer using GABA. OBSOLETE A sst GABAergic cortical interneuron transcriptomically between the sst and the pvalb families with a soma found in L2/3. Some L2/3 PV-like sst cells have Martinotti morphology while some have basket cell morphology. L2/3 PV-like sst cells have lower AP width and higher firing rate than typical Sst subclass cells. L2/3 PV-like sst cells have high maximum firing rate variability, with many classified as belonging to the pvalb subclass on the basis of electrophysiology. + L2/3 PV-like SST Mus) - Moved to PCL - see https://github.com/obophenotype/brain_data_standards_ontologies/issues/231. Use PCL:1000002 instead. + Moved to PCL. Use PCL:1000002 instead. obsolete L2/3 pvalb-like sst GABAergic cortical interneuron (Mus musculus) true @@ -89668,6 +90325,41 @@ plexiform layer using GABA. + + + + + + + + + + + + + + + A neuron that is derived from a precursor cell in the lateral ganglion eminence. + https://orcid.org/0000-0001-7258-9596 + https://orcid.org/0000-0002-7073-9172 + LGE-derived neuron + lateral ganglionic eminence derived neuron + + + + + A neuron that is derived from a precursor cell in the lateral ganglion eminence. + wikipediaversioned:Ganglionic_eminence&oldid=1186824360 + + + + + LGE-derived neuron + PMID:10377350 + + + + @@ -89702,6 +90394,7 @@ plexiform layer using GABA. ILX:0107356 Chandelier PV + In mice, Chandelier PV cells have soma found in in upper L2/3, with some in deep L5 and exhibit fast-spiking but lower firing rate compared to basket cells, and have practically absent hyperpolarization sag. chandelier pvalb GABAergic cortical interneuron @@ -89739,6 +90432,7 @@ plexiform layer using GABA. ILX:0770163 + L6b glutamatergic cortical neuron @@ -89793,6 +90487,7 @@ plexiform layer using GABA. L2/3-6 IT projecting neuron + L2/3-6 intratelencephalic projecting glutamatergic neuron @@ -89834,6 +90529,7 @@ plexiform layer using GABA. pyramidal tract (PT) neuron L5b neuron + L5 extratelencephalic projecting glutamatergic cortical neuron @@ -89908,6 +90604,7 @@ plexiform layer using GABA. L6 CT + L6 corticothalamic-projecting glutamatergic cortical neuron @@ -89940,6 +90637,7 @@ plexiform layer using GABA. L5/6 NP M1 L5/6 NP MOp + L5/6 near-projecting glutamatergic neuron of the primary motor cortex @@ -90069,6 +90767,7 @@ plexiform layer using GABA. L2/3 IT M1 L2/3 IT MOp + L2/3 intratelencephalic projecting glutamatergic neuron of the primary motor cortex @@ -90101,6 +90800,7 @@ plexiform layer using GABA. L4/5 IT M1 L4/5 IT MOp + L4/5 intratelencephalic projecting glutamatergic neuron of the primary motor cortex @@ -90171,6 +90871,7 @@ plexiform layer using GABA. L6 IT M1 L6 IT MOp + L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex @@ -90203,6 +90904,7 @@ plexiform layer using GABA. ILX:0770143 VLMC + vascular leptomeningeal cell @@ -90280,6 +90982,7 @@ plexiform layer using GABA. A mesothelial cell that has undergone mesothelial-to-mesenchymal transition (MMT) to become a fibroblast cell. + mesothelial fibroblast @@ -90336,43 +91039,44 @@ plexiform layer using GABA. - + A type of mouse mesothelial fibroblast that is derived from the neural crest, is localized on blood vessels, and is a key component of the pia and arachnoid membranes surrounding the brain. VLMC (Mus musculus) + vascular leptomeningeal cell (Mmus) - + - + - + - + PMID:30096314 - + PMID:30096314 - + PMID:30096314 @@ -90449,6 +91153,7 @@ plexiform layer using GABA. COP committed oligodendrocyte precursor + COPs are distinct from OPCs in that the lack expression of Pdgfra and Cspg4 and come out as distinct clusters in transcriptomic profiling. This is the reason that this term is not modelled as a subclassOf OPC but instead linked using develops_from. differentiation-committed oligodendrocyte precursor @@ -90624,6 +91329,7 @@ plexiform layer using GABA. A GABAergic cell located in the cerebral cortex that expresses meis2. + meis2 expressing cortical GABAergic cell @@ -90667,10 +91373,11 @@ plexiform layer using GABA. OBSOLETE A L2/3 pvalb-like sst GABAergic cortical interneuron (Mus musculus) that has Martinotti morphology. + Martinotti L2/3 PV-like SST (Mus) - Moved to PCL - see https://github.com/obophenotype/brain_data_standards_ontologies/issues/231. Use PCL:1000004 instead. + Moved to PCL. Use PCL:1000004 instead. obsolete Martinotti morphology L2/3 pvalb-like sst GABAergic cortical interneuron (Mus musculus) true @@ -90779,6 +91486,7 @@ plexiform layer using GABA. A GABAergic cortical interneuron that develops from the caudal ganglionic eminence and has migrated to the cerebral cortex. CGE cortical interneuron + caudal ganglionic eminence derived GABAergic cortical interneuron @@ -90867,9 +91575,9 @@ plexiform layer using GABA. OBSOLETE. A cell that is part of the choroid plexus. + - https://github.com/obophenotype/cell-ontology/issues/2043 obsolete choroid plexus cell true @@ -91035,10 +91743,11 @@ plexiform layer using GABA. OBSOLETE A L2/3 pvalb-like sst GABAergic cortical interneuron (Mus musculus) that has basket morphology. + basket L2/3 PV-like SST (Mus) - Moved to PCL - see https://github.com/obophenotype/brain_data_standards_ontologies/issues/231. Use PCL:1000003 instead. + Moved to PCL. Use PCL:1000003 instead. obsolete basket morphology L2/3 pvalb-like sst GABAergic cortical interneuron (Mus musculus) true @@ -92151,6 +92860,7 @@ plexiform layer using GABA. A sst GABAergic cortical interneuron that also expresses Chodl. These neurons are rare and correspond to the only known cortical interneurons with long-range projection. long-range GABAergic interneuron + sst chodl GABAergic cortical interneuron @@ -92834,6 +93544,7 @@ plexiform layer using GABA. A neurecto-epithelial cell that is part of the basal layer of the subcommissural organ and specializes in the secretion of proteins into the subarachnoid space. Hypendymal cells have similar characteristics to ependymal cells and express SCO-spondin. + hypendymal cell @@ -93104,6 +93815,7 @@ Midget bipolar cells (imb, fmb) have larger axon terminals at greater distances matrix fibroblast 1 pulmonary lipofibroblast AF1 + alveolar type 1 fibroblast cell @@ -93150,6 +93862,7 @@ Midget bipolar cells (imb, fmb) have larger axon terminals at greater distances type-2 associated stromal cell AF2 MANC + alveolar type 2 fibroblast cell @@ -93564,6 +94277,7 @@ Midget bipolar cells (imb, fmb) have larger axon terminals at greater distances 2022-05-10T13:14:00Z epithelial cell of segment 1 of proximal tubule + epithelial cell of proximal tubule segment 1 @@ -93604,6 +94318,7 @@ Midget bipolar cells (imb, fmb) have larger axon terminals at greater distances 2022-05-10T13:31:06Z epithelial cell of segment 3 of proximal tubule + epithelial cell of proximal tubule segment 3 @@ -93840,6 +94555,7 @@ Midget bipolar cells (imb, fmb) have larger axon terminals at greater distances A renal principal cell located in the connecting tubule. 2022-06-27T15:25:10Z + kidney connecting tubule principal cell @@ -94029,6 +94745,7 @@ Midget bipolar cells (imb, fmb) have larger axon terminals at greater distances A hillock cell that is located in respiratory epithelium. In some mammalian species, this cell type has been noted to express KRT13 and KRT4 and is postulated to play a role in squamous barrier function and immunomodulation. 2022-06-06T08:31:09Z hillock cell of respiratory tract + respiratory hillock cell @@ -94113,6 +94830,7 @@ Midget bipolar cells (imb, fmb) have larger axon terminals at greater distances An absorptive epithelial cell of the human intestine expressing bestrophin-4 (BEST4) calcium-activated ion channels. 2022-09-07T12:34:20Z + BEST4+ intestinal epithelial cell, human @@ -94143,6 +94861,7 @@ Midget bipolar cells (imb, fmb) have larger axon terminals at greater distances An amacrine cell that uses GABA as a neurotransmitter. 2022-10-17T12:35:11Z amacrine cell, GABAergic + GABAergic amacrine cell @@ -94172,6 +94891,7 @@ Midget bipolar cells (imb, fmb) have larger axon terminals at greater distances 2022-10-17T12:40:06Z amacrine cell, glycinergic + glycinergic amacrine cell @@ -95762,21 +96482,21 @@ Midget bipolar cells (imb, fmb) have larger axon terminals at greater distances - + An epithelial cell that is part of a ureteric bud. A ureteric bud cell has the potential to induce metanephric mesenchymal cells to proliferate and convert to epithelia that form renal tubules via: (1) the secretion of multiple diffusible growth factors that rescue renal progenitors from apoptosis and stimulate them to proliferate and (2) contact-dependent mechanisms that induce mesenchymal-epithelial conversion. https://orcid.org/0000-0002-1425-877X 2023-10-13T11:22:42Z UB cell ureteric bud cell - + - + PMID:9374839 @@ -98459,6 +99179,156 @@ Midget bipolar cells (imb, fmb) have larger axon terminals at greater distances + + + + + + + + + + + A trophoblast cell that invades the uterine wall to anchor the placenta to the uterus. An interstitial extravillous trophoblast cell differentiates from an extravillous trophoblast cell, becoming hyperchromatic and changing its morphology to a fibroblast-like spindle-shaped cell. In humans, this cell can be distinguished by the expression of placental-specific protein 8, which stimulates migration. + + 2024-01-08T15:43:15Z + invasive interstitial extravillous trophoblast cell + iEVT + interstitial extravillous trophoblast + interstitial trophoblast + interstitial extravillous trophoblast cell + + + + + A trophoblast cell that invades the uterine wall to anchor the placenta to the uterus. An interstitial extravillous trophoblast cell differentiates from an extravillous trophoblast cell, becoming hyperchromatic and changing its morphology to a fibroblast-like spindle-shaped cell. In humans, this cell can be distinguished by the expression of placental-specific protein 8, which stimulates migration. + PMID:37630754 + doi:10.1007/978-3-030-84725-8 + + + + + invasive interstitial extravillous trophoblast cell + doi:10.1007/978-3-030-84725-8 + + + + + iEVT + PMID:37630754 + + + + + + interstitial extravillous trophoblast + PMID:37630754 + + + + + interstitial trophoblast + PMID:11337369 + + + + + + + + + + + + + + + A trophoblast cell that invades the maternal spiral arteries and replace the endothelial lining, remodeling the vessels and allowing for adequate blood transport into the placenta. An endovascular extravillous trophoblast cell differentiates from an extravillous trophoblast cell. In humans, this cell can be distinguished by the expression of CD56. + + 2024-01-08T15:43:32Z + eEVT + endovascular extravillous trophoblast + endovascular trophoblast + Shortly after implantation, the endovascular extravillous trophoblast cells occlude the maternal spiral arteries, preventing premature oxygen delivery to the placental villi and reducing fetal oxidative stress. + endovascular extravillous trophoblast cell + + + + + A trophoblast cell that invades the maternal spiral arteries and replace the endothelial lining, remodeling the vessels and allowing for adequate blood transport into the placenta. An endovascular extravillous trophoblast cell differentiates from an extravillous trophoblast cell. In humans, this cell can be distinguished by the expression of CD56. + PMID:37630754 + doi:10.1007/978-3-030-84725-8 + + + + + eEVT + PMID:37630754 + + + + + + endovascular extravillous trophoblast + PMID:37630754 + + + + + endovascular trophoblast + PMID:11337369 + + + + + Shortly after implantation, the endovascular extravillous trophoblast cells occlude the maternal spiral arteries, preventing premature oxygen delivery to the placental villi and reducing fetal oxidative stress. + PMID:37630754 + + + + + + + + + + + + + + + + + + + A tissue-resident macrophage that is part of the uterus. + + 2024-01-08T16:05:09Z + uterine macrophage + Uterine macrophages are reported to be evenly distributed throughout the endometrial stroma but with aggregations observed close to the lumen of superficial secretory glands. + uterine resident macrophage + + + + + A tissue-resident macrophage that is part of the uterus. + PMID:36113384 + + + + + uterine macrophage + PMID:36113384 + + + + + Uterine macrophages are reported to be evenly distributed throughout the endometrial stroma but with aggregations observed close to the lumen of superficial secretory glands. + PMID:36113384 + + + + @@ -100846,6 +101716,12 @@ Midget bipolar cells (imb, fmb) have larger axon terminals at greater distances + + + + + + @@ -105058,6 +105934,12 @@ Midget bipolar cells (imb, fmb) have larger axon terminals at greater distances + + + + + + @@ -106702,14 +107584,14 @@ Midget bipolar cells (imb, fmb) have larger axon terminals at greater distances - + - + - + diff --git a/cl.obo b/cl.obo index 7c38c6316..02649bf25 100644 --- a/cl.obo +++ b/cl.obo @@ -1,5 +1,5 @@ format-version: 1.2 -data-version: releases/2024-01-04 +data-version: releases/2024-02-13 subsetdef: abnormal_slim "" subsetdef: added_for_HCA "" subsetdef: attribute_slim "" @@ -31,6 +31,7 @@ subsetdef: goslim_mouse "" subsetdef: goslim_pir "" subsetdef: goslim_plant "" subsetdef: goslim_pombe "" +subsetdef: goslim_prokaryote "" subsetdef: goslim_synapse "" subsetdef: goslim_yeast "" subsetdef: grouping_class "" @@ -49,7 +50,6 @@ subsetdef: non_informative "" subsetdef: organ_slim "" subsetdef: pheno_slim "" subsetdef: phenotype_rcn "" -subsetdef: prokaryote_subset "" subsetdef: ro-eco "" subsetdef: RO:0002259 "" subsetdef: scalar_slim "" @@ -62,7 +62,6 @@ subsetdef: vertebrate_core "" synonymtypedef: blast_name "" synonymtypedef: COMPARATIVE_PREFERRED "" synonymtypedef: DEPRECATED "" -synonymtypedef: DUBIOUS "" synonymtypedef: equivalent_name "" synonymtypedef: genbank_common_name "" synonymtypedef: Gene-based "" @@ -71,13 +70,14 @@ synonymtypedef: HUMAN_PREFERRED "" synonymtypedef: HUMAN_PREFERRED "preferred term when talking about an instance of this class in Homo sapiens" synonymtypedef: in_part "" synonymtypedef: INCONSISTENT "" -synonymtypedef: LATIN "" synonymtypedef: LATIN "latin term" synonymtypedef: MISSPELLING "a mis-spelling that is in common use and thus recorded" synonymtypedef: NON_MAMMAL "" synonymtypedef: OMO:0003000 "abbreviation" +synonymtypedef: OMO:0003002 "" synonymtypedef: OMO:0003003 "" synonymtypedef: OMO:0003004 "plural form" +synonymtypedef: OMO:0003011 "" synonymtypedef: PENDING_REVIEW "" synonymtypedef: PLURAL "plural term" synonymtypedef: PRO-short-label "" @@ -102,7 +102,7 @@ property_value: dc-description "An ontology of cell types." xsd:string property_value: dc-title "Cell Ontology" xsd:string property_value: dcterms-license http://creativecommons.org/licenses/by/4.0/ property_value: has_ontology_root_term CL:0000000 -property_value: owl:versionInfo "2024-01-04" xsd:string +property_value: owl:versionInfo "2024-02-13" xsd:string [Term] id: BFO:0000002 @@ -213,6 +213,7 @@ id: CL:0000000 name: cell def: "A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane." [CARO:mah] comment: The definition of cell is intended to represent all cells, and thus a cell is defined as a material entity and not an anatomical structure, which implies that it is part of an organism (or the entirety of one). +subset: cellxgene_subset subset: ubprop:upper_level xref: CALOHA:TS-2035 xref: FBbt:00007002 @@ -236,6 +237,7 @@ id: CL:0000001 name: primary cultured cell def: "A cultured cell that is freshly isolated from a organismal source, or derives in culture from such a cell prior to the culture being passaged." [ReO:mhb] comment: Covers cells actively being cultured or stored in a quiescent state for future use. +subset: cellxgene_subset synonym: "primary cell culture cell" EXACT [] synonym: "primary cell line cell" RELATED [] synonym: "unpassaged cultured cell" EXACT [] @@ -256,10 +258,11 @@ replaced_by: CLO:0000019 id: CL:0000003 name: obsolete native cell def: "OBSOLETE. A cell that is found in a natural setting, which includes multicellular organism cells 'in vivo' (i.e. part of an organism), and unicellular organisms 'in environment' (i.e. part of a natural environment)." [CARO:mah] -comment: https://github.com/obophenotype/cell-ontology/issues/2124 +subset: cellxgene_subset subset: ubprop:upper_level synonym: "cell in vivo" NARROW [] xref: CARO:0000013 +relationship: term_tracker_item https://github.com/obophenotype/cell-ontology/issues/2124 is_obsolete: true replaced_by: CL:0000000 @@ -285,6 +288,7 @@ relationship: develops_from CL:0000008 ! migratory cranial neural crest cell [Term] id: CL:0000006 name: neuronal receptor cell +subset: cellxgene_subset synonym: "neuronal receptor cell (sensu Animalia)" EXACT [] is_a: CL:0000101 ! sensory neuron is_a: CL:0000197 ! sensory receptor cell @@ -358,6 +362,7 @@ intersection_of: capable_of GO:0017145 ! stem cell division id: CL:0000015 name: male germ cell def: "A germ cell that supports male gamete production. In some species, non-germ cells known as Sertoli cells also play a role in spermatogenesis." [https://orcid.org/0000-0001-5208-3432, PMID:29462262] +subset: cellxgene_subset xref: FMA:72290 xref: MA:0002765 xref: ncithesaurus:Spermatogenic_Cell @@ -417,6 +422,7 @@ relationship: develops_from CL:0000657 ! secondary spermatocyte id: CL:0000019 name: sperm def: "A mature male germ cell that develops from a spermatid." [GOC:tfm, MESH:D013094] +subset: cellxgene_subset synonym: "sperm cell" EXACT [] synonym: "spermatozoid" EXACT [] synonym: "spermatozoon" EXACT [] @@ -451,6 +457,7 @@ relationship: bearer_of PATO:0001501 ! immature id: CL:0000021 name: female germ cell def: "Female germ cell is a germ cell that supports female gamete production." [GOC:tfm, PMID:11023867, PMID:20454446] +subset: cellxgene_subset xref: MA:0000388 xref: ncithesaurus:Egg xref: VHOG:0001530 @@ -473,6 +480,7 @@ intersection_of: capable_of GO:0017145 ! stem cell division id: CL:0000023 name: oocyte def: "A female germ cell that has entered meiosis." [GOC:tfm, ISBN:0721662544] +subset: cellxgene_subset synonym: "oogonium" RELATED [] xref: BTO:0000964 xref: CALOHA:TS-0711 @@ -489,6 +497,7 @@ relationship: participates_in GO:0007143 ! female meiotic nuclear division id: CL:0000024 name: oogonial cell def: "An undifferentiated germ cell that proliferates rapidly and gives rise to oocytes." [GOC:tfm, ISBN:0721662544] +subset: cellxgene_subset xref: FMA:83673 is_a: CL:0000021 {is_inferred="true"} ! female germ cell intersection_of: CL:0000021 ! female germ cell @@ -552,6 +561,7 @@ relationship: develops_from CL:0002676 ! neural crest derived neuroblast [Term] id: CL:0000030 name: glioblast +subset: cellxgene_subset is_a: CL:0000055 ! non-terminally differentiated cell relationship: develops_from CL:0000133 ! neurectodermal cell @@ -560,6 +570,7 @@ id: CL:0000031 name: neuroblast (sensu Vertebrata) alt_id: CL:0000337 def: "A cell that will develop into a neuron often after a migration phase." [GOC:NV, http://en.wikipedia.org/wiki/Neuroblast] +subset: cellxgene_subset synonym: "neuroblast" EXACT [] xref: BTO:0000930 xref: FMA:70563 @@ -588,6 +599,7 @@ id: CL:0000034 name: stem cell def: "A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells." [GOC:tfm, MESH:D013234] comment: This term applies to metazoan. For plant stem cells, consider using PO:0004011 ‘initial cell’ or its parent PO:0004010 ‘meristematic cell’. +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "animal stem cell" EXACT [] @@ -616,6 +628,7 @@ relationship: bearer_of PATO:0001400 ! unipotent [Term] id: CL:0000036 name: epithelial fate stem cell +subset: cellxgene_subset subset: human_reference_atlas synonym: "epithelial stem cell" EXACT [] is_a: CL:0000035 ! single fate stem cell @@ -627,6 +640,7 @@ name: hematopoietic stem cell def: "A stem cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system. Hematopoietic stem cells lack cell markers of effector cells (lin-negative). Lin-negative is defined by lacking one or more of the following cell surface markers: CD2, CD3 epsilon, CD4, CD5 ,CD8 alpha chain, CD11b, CD14, CD19, CD20, CD56, ly6G, ter119." [GOC:add, GOC:dsd, GOC:tfm, http://en.wikipedia.org/wiki/Hematopoietic_stem_cell, PMID:19022770] comment: Markers differ between species, and two sets of markers have been described for mice. HSCs are reportedly CD34-positive, CD45-positive, CD48-negative, CD150-positive, CD133-positive, and CD244-negative. subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "blood forming stem cell" EXACT [] synonym: "colony forming unit hematopoietic" RELATED [] @@ -676,6 +690,7 @@ id: CL:0000038 name: erythroid progenitor cell def: "A progenitor cell committed to the erythroid lineage." [GOC:add, ISBN:0721601464] subset: blood_and_immune_upper_slim +subset: cellxgene_subset synonym: "BFU-E" RELATED OMO:0003000 [] synonym: "blast forming unit erythroid" RELATED [] synonym: "burst forming unit erythroid" RELATED [] @@ -812,6 +827,7 @@ is_obsolete: true id: CL:0000047 name: neural stem cell def: "An undifferentiated neural cell that originates from the neuroectoderm and has the capacity both to perpetually self-renew without differentiating and to generate multiple central nervous system neuronal and glial cell types." [PMID:30639325] +subset: cellxgene_subset synonym: "neuronal stem cell" EXACT [PMID:16305818] synonym: "NSC" EXACT [] xref: BTO:0002881 @@ -840,6 +856,7 @@ id: CL:0000049 name: common myeloid progenitor def: "A progenitor cell committed to myeloid lineage, including the megakaryocyte and erythroid lineages." [GOC:add, ISBN:0878932437, MESH:D023461] comment: This cell type is intended to be compatible with any vertebrate common myeloid progenitor. For mammalian CMP known to be CD34-positive, please use the term 'common myeloid progenitor, CD34-positive' (CL_0001059). +subset: cellxgene_subset subset: human_reference_atlas synonym: "CFU-GEMM" RELATED OMO:0003000 [ISBN:0878932437] synonym: "CFU-S" RELATED OMO:0003000 [ISBN:0878932437] @@ -861,6 +878,7 @@ id: CL:0000050 name: megakaryocyte-erythroid progenitor cell def: "A progenitor cell committed to the megakaryocyte and erythroid lineages." [GOC:add, GOC:dsd, GOC:tfm, http://en.wikipedia.org/wiki/Megakaryocyte-erythroid_progenitor_cell, MESH:D055015, PMID:16647566] comment: MEPs are reportedly CD19-negative, CD34-negative, CD45RA-negative, CD110-positive, CD117-positive, and SCA1-negative and reportedly express the transcription factors GATA-1 and NF-E2. +subset: cellxgene_subset subset: human_reference_atlas synonym: "CFU-EM" EXACT [] synonym: "CFU-MegE" EXACT [] @@ -887,6 +905,7 @@ name: common lymphoid progenitor alt_id: CL:0000044 def: "A oligopotent progenitor cell committed to the lymphoid lineage." [GOC:add, GOC:dsd, GOC:tfm, PMID:10407577, PMID:16551251] comment: CLP are CD7-positive, CD10-positive, CD19-negative, CD34-positive, CD45RA-positive, CD79a-negative, CD127-positive, AA4.1-positive, RAG-negative, Sca-1-low, sIgM-negative, sIgD-negative, TdT-negative, Vpre-B-negative, and pre-BCR-negative. Expression of transcription factors include E2A-positive, EBF-positive, Ikaros-negative, PU.1-negative, and Pax5-negative. +subset: cellxgene_subset subset: human_reference_atlas synonym: "CLP" RELATED OMO:0003000 [] synonym: "committed lymphopoietic stem cell" RELATED [] @@ -923,6 +942,7 @@ id: CL:0000055 name: non-terminally differentiated cell def: "A precursor cell with a limited number of potential fates." [SANBI:mhl] comment: define using PATO mulit-potent or oligopotent? +subset: cellxgene_subset synonym: "blast cell" EXACT [] xref: BTO:0000125 xref: FMA:84782 @@ -944,6 +964,7 @@ id: CL:0000057 name: fibroblast def: "A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped." [http://en.wikipedia.org/wiki/Fibroblast, ISBN:0517223651, MESH:D005347] comment: These cells may be vimentin-positive, fibronectin-positive, fsp1-positive, MMP-1-positive, collagen I-positive, collagen III-positive, and alpha-SMA-negative. +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas xref: BTO:0000452 @@ -1024,6 +1045,7 @@ id: CL:0000062 name: osteoblast def: "Skeletogenic cell that secretes osteoid, is capable of producing mineralized (hydroxyapatite) matrix, is located adjacent to or within osteoid tissue, and arises from the transformation of a preosteoblast cell." [GO_REF:0000034, MESH:D010006] comment: non-encoded relationships from VSAO - capable_of_producing VSAO:0000020 +subset: cellxgene_subset xref: BTO:0001593 xref: CALOHA:TS-0720 xref: FMA:66780 @@ -1047,6 +1069,7 @@ consider: CL:0001034 id: CL:0000064 name: ciliated cell def: "A cell that has a filiform extrusion of the cell surface." [GOC:tfm] +subset: cellxgene_subset xref: VHOG:0001532 xref: XAO:0000031 is_a: CL:0000000 ! cell @@ -1059,6 +1082,7 @@ relationship: has_part GO:0005929 ! cilium id: CL:0000065 name: ependymal cell def: "A neurectoderm derived cell that lines the neural lumen." [GOC:tfm, JB:jb, PMID:9550134] +subset: cellxgene_subset subset: human_reference_atlas synonym: "ependymocyte" EXACT [] xref: BTO:0001724 @@ -1071,6 +1095,7 @@ relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens id: CL:0000066 name: epithelial cell def: "A cell that is usually found in a two-dimensional sheet with a free surface. The cell has a cytoskeleton that allows for tight cell to cell contact and for cell polarity where apical part is directed towards the lumen and the basal part to the basal lamina." [FB:ma, GOC:tfm, MESH:D004847] +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "epitheliocyte" EXACT [] @@ -1090,6 +1115,7 @@ property_value: depiction "https://www.swissbiopics.org/api/image/Epithelial_cel id: CL:0000067 name: ciliated epithelial cell def: "An epithelial cell that has a cilia." [GOC:tfm] +subset: cellxgene_subset xref: FMA:70605 is_a: CL:0000064 ! ciliated cell is_a: CL:0000066 ! epithelial cell @@ -1100,6 +1126,7 @@ intersection_of: has_part GO:0005929 ! cilium id: CL:0000068 name: duct epithelial cell def: "An epithelial cell that is part of a duct." [https://orcid.org/0000-0001-5208-3432] +subset: cellxgene_subset is_a: CL:0000066 ! epithelial cell intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0000058 ! duct @@ -1119,6 +1146,7 @@ is_obsolete: true id: CL:0000071 name: blood vessel endothelial cell def: "An endothelial cell that lines the vasculature." [GOC:tfm] +subset: cellxgene_subset subset: human_reference_atlas synonym: "cuboidal endothelial cell of vascular tree" EXACT [] is_a: CL:0000076 {is_inferred="true"} ! squamous epithelial cell @@ -1138,7 +1166,7 @@ is_a: CL:0002078 ! meso-epithelial cell [Term] id: CL:0000073 name: obsolete barrier epithelial cell -comment: https://github.com/obophenotype/cell-ontology/issues/1149 +relationship: term_tracker_item https://github.com/obophenotype/cell-ontology/issues/1149 is_obsolete: true replaced_by: CL:0000215 @@ -1153,6 +1181,7 @@ replaced_by: PO:0000066 id: CL:0000075 name: columnar/cuboidal epithelial cell def: "A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube." [GO:0002065, https://orcid.org/0000-0001-5208-3432] +subset: cellxgene_subset subset: human_reference_atlas is_a: CL:0000066 ! epithelial cell relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens @@ -1160,6 +1189,7 @@ relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: CL:0000076 name: squamous epithelial cell +subset: cellxgene_subset xref: CALOHA:TS-1249 is_a: CL:0000066 ! epithelial cell @@ -1167,6 +1197,7 @@ is_a: CL:0000066 ! epithelial cell id: CL:0000077 name: mesothelial cell def: "A flattened epithelial cell of mesenchymal origin that lines the serous cavity." [GOC:tfm, ISBN:0721662544] +subset: cellxgene_subset subset: human_reference_atlas synonym: "mesotheliocyte" EXACT [] xref: FMA:66773 @@ -1183,6 +1214,7 @@ is_a: CL:0000076 ! squamous epithelial cell [Term] id: CL:0000079 name: stratified epithelial cell +subset: cellxgene_subset is_a: CL:0000066 ! epithelial cell relationship: develops_from CL:0000357 ! stratified epithelial stem cell @@ -1199,6 +1231,7 @@ relationship: part_of UBERON:0000179 ! haemolymphatic fluid id: CL:0000081 name: blood cell def: "A cell found predominately in the blood." [GOC:add, GOC:tfm] +subset: cellxgene_subset subset: general_cell_types_upper_slim xref: FMA:62844 xref: MESH:D001773 @@ -1211,6 +1244,7 @@ relationship: capable_of GO:0008015 ! blood circulation id: CL:0000082 name: epithelial cell of lung def: "An epithelial cell of the lung." [https://orcid.org/0000-0001-5208-3432] +subset: cellxgene_subset synonym: "lung epithelial cell" EXACT [] xref: BTO:0004299 is_a: CL:0000066 ! epithelial cell @@ -1237,6 +1271,7 @@ name: T cell alt_id: CL:0000804 alt_id: CL:0000812 def: "A type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex." [GOC:add, GOC:tfm, ISBN:0781735149] +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "immature T cell" RELATED [] @@ -1261,7 +1296,7 @@ relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens id: CL:0000085 name: obsolete germ line stem cell (sensu Vertebrata) comment: Obsoleted as there is no need for a term specific for vertebrates. -property_value: term_tracker_item "https://github.com/obophenotype/cell-ontology/issues/1935" xsd:string +relationship: term_tracker_item https://github.com/obophenotype/cell-ontology/issues/1935 is_obsolete: true replaced_by: CL:0000014 @@ -1269,7 +1304,7 @@ replaced_by: CL:0000014 id: CL:0000086 name: obsolete germ line stem cell (sensu Nematoda and Protostomia) comment: Obsoleted as there is no need for a term specific for nematods and protostomes. -property_value: term_tracker_item "https://github.com/obophenotype/cell-ontology/issues/1935" xsd:string +relationship: term_tracker_item https://github.com/obophenotype/cell-ontology/issues/1935 is_obsolete: true replaced_by: CL:0000014 @@ -1277,7 +1312,7 @@ replaced_by: CL:0000014 id: CL:0000087 name: obsolete male germ line stem cell (sensu Nematoda and Protostomia) comment: Obsoleted as there is no need for a term specific for nematods and protostomes. -property_value: term_tracker_item "https://github.com/obophenotype/cell-ontology/issues/1935" xsd:string +relationship: term_tracker_item https://github.com/obophenotype/cell-ontology/issues/1935 is_obsolete: true replaced_by: CL:0000016 @@ -1285,7 +1320,7 @@ replaced_by: CL:0000016 id: CL:0000088 name: obsolete female germ line stem cell (sensu Nematoda and Protostomia) comment: Obsoleted as there is no need for a term specific for nematods and protostomes. -property_value: term_tracker_item "https://github.com/obophenotype/cell-ontology/issues/1935" xsd:string +relationship: term_tracker_item https://github.com/obophenotype/cell-ontology/issues/1935 is_obsolete: true replaced_by: CL:0000022 @@ -1293,7 +1328,7 @@ replaced_by: CL:0000022 id: CL:0000089 name: obsolete male germ line stem cell (sensu Vertebrata) comment: Obsoleted as there is no need for a term specific for vertebrates. -property_value: term_tracker_item "https://github.com/obophenotype/cell-ontology/issues/1935" xsd:string +relationship: term_tracker_item https://github.com/obophenotype/cell-ontology/issues/1935 is_obsolete: true replaced_by: CL:0000016 @@ -1301,7 +1336,7 @@ replaced_by: CL:0000016 id: CL:0000090 name: obsolete female germ line stem cell (sensu Vertebrata) comment: Obsoleted as there is no need for a term specific for vertebrates. -property_value: term_tracker_item "https://github.com/obophenotype/cell-ontology/issues/1935" xsd:string +relationship: term_tracker_item https://github.com/obophenotype/cell-ontology/issues/1935 is_obsolete: true replaced_by: CL:0000022 @@ -1310,6 +1345,7 @@ id: CL:0000091 name: Kupffer cell def: "A tissue-resident macrophage of the reticuloendothelial system found on the luminal surface of the hepatic sinusoids involved in erythrocyte clearance. Markers include F4/80+, CD11b-low, CD68-positive, sialoadhesin-positive, CD163/SRCR-positive. Irregular, with long processes including lamellipodia extending into the sinusoid lumen, have flattened nucleus with cytoplasm containing characteristic invaginations of the plasma membrane (vermiform bodies); lie within the sinusoid lumen attached to the endothelial surface; derived from the bone marrow, form a major part of the body's mononuclear phagocyte system." [GO_REF:0000031, GOC:add, GOC:tfm, ISBN:0517223651, MESH:D007728, PMID:15771589, PMID:17105582] comment: Markers: Mouse: F4/80+, CD11b-low, CD68+, sialoadhesin+, CD163/SRCR+; role or process: immune, antigen-presentation, clearance of senescent erythrocytes, iron metabolism. Kupffer cells are also reportedly C3aR-positive, CD14-low, CD54-positive, CD88-positive, and CD284-positive. They are also capable of producing IL-1, IL-6, TNF-alpha, nitric oxide, PGD2, PGE2, PGF2alpha, and TXA2. +subset: cellxgene_subset subset: human_reference_atlas synonym: "hepatic macrophage" EXACT [] synonym: "littoral cell of hepatic sinusoid" EXACT [] @@ -1341,6 +1377,7 @@ id: CL:0000092 name: osteoclast def: "A specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue, which typically differentiates from monocytes. This cell has the following markers: tartrate-resistant acid phosphatase type 5-positive, PU.1-positive, c-fos-positive, nuclear factor NF-kappa-B p100 subunit-positive, tumor necrosis factor receptor superfamily member 11A-positive and macrophage colony-stimulating factor 1 receptor-positive." [GO_REF:0000031, GOC:add, GOC:tfm, ISBN:0781735149, PMID:10428500, PMID:15055519, PMID:17380158] comment: Morphology: Highly vesicular; markers: Surface: RANK, cFMS (MCSF receptor); Secreted: cathepsin K and TRAP (tartate resistant acid phosphatase); transcription factors: PU.1, cFOS, MITF, NFkB (p52); role or process: tissue remodelling: bone resorption; lineage: hematopoietic, myeloid. +subset: cellxgene_subset synonym: "chondroclast" RELATED [] xref: BTO:0000968 xref: CALOHA:TS-0721 @@ -1381,6 +1418,7 @@ is_obsolete: true id: CL:0000094 name: granulocyte def: "A leukocyte with abundant granules in the cytoplasm." [GOC:amm, GOC:tfm, http://en.wikipedia.org/wiki/Granulocyte, MESH:D006098] +subset: cellxgene_subset subset: human_reference_atlas synonym: "granular leucocyte" EXACT [] synonym: "granular leukocyte" EXACT [] @@ -1415,6 +1453,7 @@ relationship: RO:0002104 PR:000001969 ! has plasma membrane part urokinase plasm [Term] id: CL:0000095 name: neuron associated cell +subset: cellxgene_subset is_a: CL:0002319 ! neural cell relationship: develops_from CL:0000133 ! neurectodermal cell @@ -1461,6 +1500,7 @@ name: mast cell def: "A cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation. Progenitors leave bone marrow and mature in connective and mucosal tissue. Mature mast cells are found in all tissues, except the bloodstream. Their phenotype is CD117-high, CD123-negative, CD193-positive, CD200R3-positive, and FceRI-high. Stem-cell factor (KIT-ligand; SCF) is the main controlling signal of their survival and development." [GOC:add, GOC:dsd, GOC:tfm, ISBN:068340007X, MESH:D008407, PMCID:PMC1312421, PMCID:PMC2855166, PMID:15153310, PMID:16455980, PMID:19671378, PMID:212366338, PMID:9354811] comment: Mast cells are generally integrin beta-7-negative and positive for TLR2, TLR3, TLR4, TLR5, TLR7, TLR9, C3aR, C5aR, CR3, CR4, VEGF, FGF2, and renin. They can express MHC Class I and II on their surface. Activated murine mast cells (IgE+Antigen) were capable of expressing the following co-stimulatory molecules: CD95 (Fas), CD120b, CD137 (4-1BB), CD153 (CD30L), CD154 (CD40L), GITR, ICOSL, OX40L, PD-L1, and PD-L2. Note that there was some mouse strain variation. Mast cells have also been demonstrated to produce bFGF, CCL2, CCL4, CCL5, CCL11, CCL20, CXCL2, CXCL8, CXCL10, GM-CSF, IFN-gamma, IL-1, IL-2, IL-3, IL-8, IL-10, IL-11, IL-12, IL-13, IL-16, IL-25, IL-18, MIP-1, prostaglandin D2, SCF, TGF-beta, TNF-alpha, TSLP, VEGF, and XCL1. They express the transcription factors Transcription factors AP-1, GATA1, MITF, Notch2, PIAS3, PU.1, and STAT5. subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "histaminocyte" EXACT [] synonym: "labrocyte" EXACT [ISBN:0721601464] @@ -1516,6 +1556,7 @@ intersection_of: capable_of GO:0050906 ! detection of stimulus involved in senso id: CL:0000099 name: interneuron def: "Most generally any neuron which is not motor or sensory. Interneurons may also refer to neurons whose axons remain within a particular brain region as contrasted with projection neurons which have axons projecting to other brain regions." [GOC:tfm, MESH:D007395] +subset: cellxgene_subset subset: human_reference_atlas xref: BTO:0003811 xref: FBbt:00005125 @@ -1528,6 +1569,7 @@ relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens id: CL:0000100 name: motor neuron def: "An efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes or inhibits movement." [MESH:D009046, PMID:16875686] +subset: cellxgene_subset subset: human_reference_atlas synonym: "motoneuron" EXACT [] xref: BTO:0000312 @@ -1561,6 +1603,7 @@ id: CL:0000103 name: bipolar neuron def: "A type of interneuron that has two neurites, usually an axon and a dendrite, extending from opposite poles of an ovoid cell body." [GOC:tfm, ISBN:0444009442] subset: BDS_subset +subset: cellxgene_subset xref: FMA:67282 is_a: CL:0000099 ! interneuron intersection_of: CL:0000099 ! interneuron @@ -1642,6 +1685,7 @@ is_a: CL:0000540 ! neuron id: CL:0000113 name: mononuclear phagocyte def: "A vertebrate phagocyte with a single nucleus." [GOC:add, GOC:tfm, ISBN:0781735149] +subset: cellxgene_subset subset: human_reference_atlas xref: BTO:0001433 is_a: CL:0000518 {is_inferred="true"} ! phagocyte (sensu Vertebrata) @@ -1653,6 +1697,7 @@ relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: CL:0000114 name: surface ectodermal cell +subset: cellxgene_subset synonym: "cell of surface ectoderm" EXACT [] synonym: "surface ectoderm cell" EXACT [] xref: FMA:72552 @@ -1663,6 +1708,7 @@ id: CL:0000115 name: endothelial cell def: "An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal. In mammals, endothelial cell has vimentin filaments and is derived from the mesoderm." [GOC:tfm, http://en.wikipedia.org/wiki/Endothelial_cell, https://sourceforge.net/tracker/?func=detail&atid=440764&aid=3364936&group_id=36855, MESH:D042783, PMID:21275341] comment: From FMA: 9.07.2001: Endothelial cell has always been classified as a kind of epithelial cell, specifically a squamous cell but that is not true. First, endothelial cell can either be squamous or cuboidal (e.g. high-endothelial cell) and secondly, it has different embryological derivation (mesodermal) than a true epithelial cell (ectodermal and endodermal). The basis for present classification is the fact that it comprises the outermost layer or lining of anatomical structures (location-based) but a better structural basis for the differentia is the cytoskeleton of the cell. Endothelial cell has vimentin filaments while an epithelial cell has keratin filaments. [Onard]. +subset: cellxgene_subset subset: human_reference_atlas synonym: "endotheliocyte" EXACT [] xref: BTO:0001176 @@ -1703,6 +1749,7 @@ relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 id: CL:0000119 name: cerebellar Golgi cell def: "Large intrinsic neuron located in the granule layer of the cerebellar cortex that extends its dendrites into the molecular layer where they receive contact from parallel fibers. The axon of the Golgi cell ramifies densely in the granule layer and enters into a complex arrangement with mossy fiber terminals and granule cell dendrites to form the cerebellar glomerulus. Llinas, Walton and Lang. In The Synaptic Organization of the Brain. 5th ed. 2004." [NIFSTD:sao1415726815] +subset: cellxgene_subset synonym: "cerebellar Golgi neuron" EXACT [] synonym: "cerebellum Golgi cell" EXACT [] synonym: "Golgi cell" EXACT [] @@ -1714,6 +1761,7 @@ is_a: CL:4023057 ! cerebellar inhibitory GABAergic interneuron id: CL:0000120 name: granule cell def: "A neuron of the vertebrate central nervous system that is small in size. This general class includes small neurons in the granular layer of the cerebellar cortex, cerebral cortex neurons that are not pyramidal cells and small neurons without axons found in the olfactory bulb." [https://medical-dictionary.thefreedictionary.com/granule+cell] +subset: cellxgene_subset xref: BTO:0003393 is_a: CL:0000117 ! CNS neuron (sensu Vertebrata) @@ -1721,6 +1769,7 @@ is_a: CL:0000117 ! CNS neuron (sensu Vertebrata) id: CL:0000121 name: Purkinje cell def: "The output neuron of the cerebellar cortex." [MESH:D011689] +subset: cellxgene_subset synonym: "cerebellar Purkinje cell" EXACT [] synonym: "cerebellum Purkinje cell" EXACT [] synonym: "Purkinje neuron" EXACT [] @@ -1738,6 +1787,7 @@ id: CL:0000122 name: stellate neuron def: "A neuron that has dendritic processes radiating from the cell body forming a star-like shape." [ISBN:9780123973481] subset: BDS_subset +subset: cellxgene_subset xref: BTO:0002316 is_a: CL:0000104 ! multipolar neuron is_a: CL:0000117 ! CNS neuron (sensu Vertebrata) @@ -1748,6 +1798,7 @@ relationship: bearer_of PATO:0070010 ! stellate morphology [Term] id: CL:0000123 name: neuron associated cell (sensu Vertebrata) +subset: cellxgene_subset is_a: CL:0000095 ! neuron associated cell is_a: CL:0000255 ! eukaryotic cell relationship: develops_from CL:0000333 ! migratory neural crest cell @@ -1757,7 +1808,7 @@ relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata id: CL:0000124 name: obsolete glial cell (sensu Nematoda and Protostomia) comment: This is a grouping class that is no longer needed or wanted. -property_value: seeAlso "https://github.com/obophenotype/cell-ontology/issues/715" xsd:string +relationship: term_tracker_item https://github.com/obophenotype/cell-ontology/issues/715 is_obsolete: true [Term] @@ -1765,6 +1816,7 @@ id: CL:0000125 name: glial cell def: "A non-neuronal cell of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu. Guide neuronal migration during development, and exchange metabolites with neurons." [MESH:D009457] comment: Not all glial cells develop from glioblasts, with microglia developing from the mesoderm instead. See https://github.com/obophenotype/cell-ontology/issues/1571 +subset: cellxgene_subset subset: general_cell_types_upper_slim synonym: "neuroglia" RELATED [] synonym: "neuroglial cell" EXACT [] @@ -1778,6 +1830,7 @@ is_a: CL:0000095 ! neuron associated cell id: CL:0000126 name: macroglial cell def: "A neuroglial cell of ectodermal origin, i.e., the astrocytes and oligodendrocytes considered together." [GOC:tfm, ISBN:0721662544] +subset: cellxgene_subset synonym: "macroglia" RELATED OMO:0003004 [doi:10.1152/physrev.2001.81.2.871] synonym: "macrogliocyte" EXACT [] xref: BTO:0000771 @@ -1791,6 +1844,7 @@ id: CL:0000127 name: astrocyte def: "A class of large neuroglial (macroglial) cells in the central nervous system - the largest and most numerous neuroglial cells in the brain and spinal cord. Astrocytes (from 'star' cells) are irregularly shaped with many long processes, including those with 'end feet' which form the glial (limiting) membrane and directly and indirectly contribute to the blood-brain barrier. They regulate the extracellular ionic and chemical environment, and 'reactive astrocytes' (along with microglia) respond to injury." [GOC:dsd, GOC:tfm, http://en.wikipedia.org/wiki/Astrocyte, MESH:D001253, PMID:11746784, PMID:12162730, PMID:12898703, PMID:20942978] comment: Astrocytes are reportedly CD68-negative, CD121a-positive, CD184-positive, CD192-positive, CRF-positive, EGFR-positive, GFAP-positive, GLUT1-positive, MBP-negative, and NGFR-positive. +subset: cellxgene_subset subset: human_reference_atlas synonym: "astrocytic glia" EXACT [] xref: BTO:0000099 @@ -1804,6 +1858,7 @@ id: CL:0000128 name: oligodendrocyte def: "A class of large neuroglial (macroglial) cells in the central nervous system. Form the insulating myelin sheath of axons in the central nervous system." [http://en.wikipedia.org/wiki/Oligodendrocyte, MESH:D009836] comment: Oligodendrocytes are reportedly MDP-positive and CD4-negative. +subset: cellxgene_subset subset: human_reference_atlas synonym: "oligodendroglia" RELATED [] synonym: "OLs" EXACT [PMID:8734446] @@ -1821,6 +1876,7 @@ id: CL:0000129 name: microglial cell def: "A central nervous system macrophage found in the parenchyma of the central nervous system. Marker include CD11b-positive, F4/80-positive, and CD68-positive." [GOC:add, GOC:dsd, GOC:tfm, http://en.wikipedia.org/wiki/Microglia, ISBN:0721601464, MESH:D017628, PMID:11517395, PMID:12430718, PMID:14561199, PMID:14612429, PMID:16177057, PMID:19461673, PMID:2089275] comment: Unlike macroglial cells, microglial cells arise from hematopoietic stem cells in the yolk sac during early embryogenesis that populate the central nervous system. They derive from embryonic mesoderm and are not from neuroectoderm where glioblast develops from. Markers: Mouse: CD11b+, F4/80+, CD68+. They represent ~12% of the cells in the CNS, but they are not uniformly distributed within the CNS. A normal adult mouse brain has approximately 3.5x10e6 microglia. Microglia are also reportedly CD3-negative, CD4-positive, CD8-negative, CD11b-positive, CD11c-high, CD14-negative, CD19-negative, CD45-low, CD56-negative, CD163-negative, CD200R-positive, CD281-positive, CD282-positive, CD283-positive, CD284-positive, CD285-positive, CD286-positive, CD287-positive, CD288-positive, CD289-positive, Gr1-negative, nestin-positive, and PU.1-positive. {xref="PMID:23616747"} +subset: cellxgene_subset subset: human_reference_atlas synonym: "brain macrophage" BROAD [] synonym: "brain-resident macrophage" EXACT [] @@ -1857,6 +1913,7 @@ relationship: only_in_taxon NCBITaxon:33317 ! Protostomia [Term] id: CL:0000131 name: gut endothelial cell +subset: cellxgene_subset is_a: CL:0000115 ! endothelial cell relationship: develops_from CL:0000223 ! endodermal cell @@ -1864,6 +1921,7 @@ relationship: develops_from CL:0000223 ! endodermal cell id: CL:0000132 name: corneal endothelial cell def: "An hexagonal, flattened, mitochondria-rich endothelial cell that forms a monolayer on the posterior surface of the cornea (the corneal endothelium). Corneal endothelial cells are derived from the neural crest and are responsible for keeping the cornea transparent by maintaining the tissue in a semi-dry state through the action of their ionic pumps and tight junction barrier." [GOC:tfm, PMID:21976958, PMID:23284695, PMID:34741068, PMID:36769303] +subset: cellxgene_subset subset: eye_upper_slim subset: human_reference_atlas xref: CALOHA:TS-0172 @@ -1887,6 +1945,7 @@ name: mesenchymal stem cell alt_id: CL:0002452 def: "A connective tissue cell that normally gives rise to other cells that are organized as three-dimensional masses. In humans, this cell type is CD73-positive, CD90-positive, CD105-positive, CD45-negative, CD34-negative, and MHCII-negative. They may further differentiate into osteoblasts, adipocytes, myocytes, neurons, or chondroblasts in vitro. Originally described as residing in the bone marrow, this cell type is now known to reside in many, if not all, adult organs." [FB:ma, GOC:dsd, http://en.wikipedia.org/wiki/Mesenchymal_stem_cell, http://www.copewithcytokines.de/cope.cgi?key=mesenchymal%20stem%20cells, PMCID:PMC2613570, PMID:10102814, PMID:16923606, PMID:17986482, PMID:19960544] comment: Many but not all mesenchymal cells derive from the mesoderm. MSCs are reportedly CD3-negative, CD4-negative, CD5-negative, CD8-negative, CD11a-negative, CD11b-negative, CD14-negative, CD19-negative, CD29-positive, CD31-negative, CD34-negative, CD38-negative, CD40-negative, CD44-positive, CD45-negative, CD49-positive, CD54-positive, CD66b-negative, CD79a-negative, CD80-negative, CD102-positive, CD106-positive, CD117-positive, CD121a-positive, CD121b-positive, CD123-positive, CD124-positive, CD133-negative, CD146-positive, CD166-positive, CD271-positive, B220-negative, Gr1-negative, MHCI-positive, MHCII-negative, SSEA4-negative, sca1-positive, Ter119-negative, and glycophorin A-negative. Cultured MSCs are capable of producing stem cell factor, IL7, IL8, IL11, TGF-beta, cofilin, galectin-1, laminin-receptor 1, cyclophilin A, and MMP-2. +subset: cellxgene_subset synonym: "BMSC" RELATED OMO:0003000 [] synonym: "bone marrow stromal cells" NARROW [] synonym: "CFU-F" RELATED OMO:0003000 [] @@ -1911,6 +1970,7 @@ id: CL:0000135 name: fibrocyte def: "An inactive fibroblast; cytoplasm is sparse, endoplasmic reticulum is scanty with flattened nucleus. Term used by some histologists; when fibroblasts become relatively inactive in fiber formation. However, this cell has the potential for fibrogenesis in quiescent connective tissue of the adult, as well as during development, other histologists prefer to use the term fibroblast in all circumstances. These cells represent ~0.5% of peripheral blood leukocytes." [GOC:dsd, GOC:tfm, http://en.wikipedia.org/wiki/Fibrocyte, ISBN:0412046911, ISBN:0517223651, PMID:11641248, PMID:15010326, PMID:17607298, PMID:18222966, PMID:8790603, PMID:9551999] comment: Cultured human fibrocytes are MHCI-positive, MHCII-positive, CD1a-negative, CD3-negative, CD4-negative, CD8-negative, CD10-negative, CD11b-positive, CD13-positive, CD14-negative, CD16-negative, CD18-positive, CD19-negative, CD25-negative, CD29-positive, CD32-positive, CD33-negative, CD34-positive, CD38-negative, CD40-positive, CD44-negative, CD45RO-positive, CD49a-positive, CD49b-positive, CD49c-negative, CD49d-negative, CD49e-positive, CD49f-negative, CD56-negative, CD58-positive, CD61-positive, CD64-positive, CD70-negative, CD71-positive, CD80-positive, CD83-negative, CD86-positive, CD103-negative, CD105-positive, CD181-positive, CD182-negative, CD183-positive, CD184-positive, CD185-negative, CD186-negative, CD191-positive, CD192-negative, CD193-positive, CD194-positive, CD195-positive, CD196-negative, CD197-positive, CD199-positive, desmin-negative, F4/80-positive, Gr1-positive, LSP-1-positive, MHCI-positive, MHCII-positive, alpha-SMA-negative, TCRab-negative, TCRgd-negative, and vimentin-positive. Fibrocytes are also capable of secreting angiogenin, bFGF, CCL2, CCL3, CCL4, CCL8, CXCL1, type I collagen, type III collagen, CTGF, fibronectin, GM-CSF, IL-1a, IL-6, IL-8, IL-10, M-CSF, MMP-9, PDGF-A, TGF-alpha, TGF-beta1, TNF-alpha, and VEGF-A. +subset: cellxgene_subset xref: FMA:63879 is_a: CL:0000499 {is_inferred="true"} ! stromal cell intersection_of: CL:0000499 ! stromal cell @@ -1925,6 +1985,7 @@ id: CL:0000136 name: adipocyte alt_id: CL:0000450 def: "A fat-storing cell found mostly in the abdominal cavity and subcutaneous tissue of mammals. Fat is usually stored in the form of triglycerides." [MESH:D017667] +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "adipose cell" EXACT [] @@ -1956,6 +2017,7 @@ relationship: part_of UBERON:0002481 ! bone tissue id: CL:0000138 name: chondrocyte def: "Skeletogenic cell that is terminally differentiated, secretes an avascular, GAG-rich matrix, is embedded in cartilage tissue matrix, retains the ability to divide, and develops from a chondroblast cell." [GO_REF:0000034, MESH:D019902] +subset: cellxgene_subset synonym: "cartilage cell" EXACT [] xref: BTO:0000249 xref: CALOHA:TS-0138 @@ -2014,6 +2076,7 @@ name: professional antigen presenting cell def: "A cell capable of processing and presenting lipid and protein antigens to T cells in order to initiate an immune response." [GOC:add, ISBN:0781735149] comment: Note change of name; nearly all somatic cells can present antigens to T cells via MHC Class I complexes leading to effector responses, but professional antigen presenting cells constitutively express MHC Class II as well as costimulatory molecules, and thus can initiate immune responses via T cells. subset: blood_and_immune_upper_slim +subset: cellxgene_subset synonym: "APC" RELATED OMO:0003000 [] is_a: CL:0000738 ! leukocyte intersection_of: CL:0000738 ! leukocyte @@ -2041,6 +2104,7 @@ id: CL:0000148 name: melanocyte alt_id: CL:0000572 def: "A pigment cell derived from the neural crest. Contains melanin-filled pigment granules, which gives a brown to black appearance." [SANBI:mhl] +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "melanophore" NARROW [] @@ -2067,6 +2131,7 @@ is_a: CL:0000147 ! pigment cell id: CL:0000150 name: glandular epithelial cell def: "A specialized epithelial cell that is capable of synthesizing and secreting certain biomolecules." [GOC:tfm] +subset: cellxgene_subset xref: CALOHA:TS-2085 xref: FMA:86494 is_a: CL:0000066 ! epithelial cell @@ -2077,6 +2142,7 @@ relationship: part_of UBERON:0006799 ! glandular epithelium id: CL:0000151 name: secretory cell def: "A cell that specializes in controlled release of one or more substances." [GOC:tfm, ISBN:0721662544] +subset: cellxgene_subset xref: BTO:0003659 xref: FMA:86916 is_a: CL:0000000 ! cell @@ -2116,6 +2182,7 @@ relationship: capable_of GO:0009306 ! protein secretion id: CL:0000155 name: peptic cell def: "A cell that is usually basal in position, cuboidal with round nucleus, short microvilli, secretes pepsinogen." [GOC:tfm] +subset: cellxgene_subset synonym: "chief cell of stomach" EXACT [] synonym: "gastric chief cell" EXACT [] synonym: "pepsinogen secreting cell" EXACT [] @@ -2144,6 +2211,7 @@ relationship: capable_of GO:0043129 ! surfactant homeostasis id: CL:0000158 name: club cell def: "A non-mucous, epithelial secretory cell that is part of the tracheobronchial tree. A club cell has short microvilli but no cilia. A club cell is able to multiply and differentiate into ciliated cells to regenerate the bronchiolar epithelium and it also protects the tracheobronchial epithelium." [DOI:10.1183/09031936.00146609, DOI:10.1378/chest.12-2762, GOC:tfm, PMID:28128362, PMID:29874100, PMID:7905712] +subset: cellxgene_subset subset: human_reference_atlas synonym: "Clara cell" EXACT [] xref: BTO:0004811 @@ -2163,6 +2231,7 @@ is_a: CL:0000151 ! secretory cell id: CL:0000160 name: goblet cell def: "A cell of the epithelial lining that produce and secrete mucins." [MESH:D020397] +subset: cellxgene_subset synonym: "chalice cell" EXACT [] xref: BTO:0001540 xref: FMA:13148 @@ -2173,7 +2242,7 @@ is_a: CL:0000319 ! mucus secreting cell [Term] id: CL:0000161 name: obsolete acid secreting cell -comment: https://github.com/obophenotype/cell-ontology/issues/427 +relationship: term_tracker_item https://github.com/obophenotype/cell-ontology/issues/427 is_obsolete: true consider: CL:0000162 @@ -2181,6 +2250,7 @@ consider: CL:0000162 id: CL:0000162 name: parietal cell def: "A large, oval stomach epithelial cell with a central nucleus; source of gastric acid. Secretes HCl." [GOC:tfm, ISBN:0517223651] +subset: cellxgene_subset synonym: "oxyntic cell" EXACT [] xref: BTO:0001780 xref: FMA:62901 @@ -2191,6 +2261,7 @@ relationship: capable_of GO:0046717 ! acid secretion id: CL:0000163 name: endocrine cell def: "A cell of an endocrine gland, ductless glands that secrete substances which are released directly into the circulation and which influence metabolism and other body functions." [MESH:D055098] +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "endocrinocyte" EXACT [] @@ -2206,6 +2277,7 @@ relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens id: CL:0000164 name: enteroendocrine cell def: "An endocrine cell that is located in the epithelium of the gastrointestinal tract or in the pancreas." [GOC:tfm, SANBI:mhl] +subset: cellxgene_subset xref: BTO:0003865 xref: FMA:62930 xref: MESH:D019858 @@ -2217,6 +2289,7 @@ id: CL:0000165 name: neuroendocrine cell def: "A neuron that is capable of some hormone secretion in response to neuronal signals." [MESH:D055099] comment: The neurosecretory cell is neither an ordinary neuron nor an endocrine cell, but a combination of both. Its neuronal features resemble those of ordinary neurons concerning both structure and function. The production of a visible secretory material marks the neurosecretory neuron as a gland cell, and the fact that extractable cellular products act in the manner of hormones places it in the realm of endocrine elements. \n\nThe modern definition of neurosecretion has evolved to include the release of any neuronal secretory product from a neuron. {xref="https://www.clinicalkey.com/#!/content/book/3-s2.0-B9780323555968000073", xref="PMID:5342440"} +subset: cellxgene_subset subset: human_reference_atlas synonym: "neurosecretory cell" RELATED [] synonym: "neurosecretory neuron" RELATED [] @@ -2234,6 +2307,7 @@ relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens id: CL:0000166 name: chromaffin cell def: "A cell that stores epinephrine secretory vesicles. During times of stress, the nervous system signals the vesicles to secrete their hormonal content. Their name derives from their ability to stain a brownish color with chromic salts. Characteristically, they are located in the adrenal medulla and paraganglia of the sympathetic nervous system." [MESH:D019439] +subset: cellxgene_subset synonym: "phaeochromocyte" EXACT [] xref: BTO:0000259 xref: FMA:69263 @@ -2263,6 +2337,7 @@ id: CL:0000169 name: type B pancreatic cell def: "A cell that secretes insulin and is located towards the center of the islets of Langerhans." [GOC:tfm, http://en.wikipedia.org/wiki/Pancreatic_b_cell, ISBN:0517223651] comment: Pancreatic beta cells are also reportedly CD284-positive. Upon activation, they upregulate their CD14 expression. +subset: cellxgene_subset subset: human_reference_atlas synonym: "B-cell of pancreatic islet" EXACT [FMA:70586] synonym: "beta cell" BROAD [ZFA:0009102] @@ -2303,6 +2378,7 @@ relationship: capable_of GO:0070091 ! glucagon secretion id: CL:0000171 name: pancreatic A cell def: "A type of enteocrine cell found in the periphery of the islets of Langerhans that secretes glucagon." [GOC:tfm, ISBN:0721662544] +subset: cellxgene_subset subset: human_reference_atlas synonym: "alpha cell of islet of Langerhans" EXACT [] synonym: "pancreatic alpha cell" EXACT [] @@ -2329,6 +2405,7 @@ relationship: capable_of GO:0070253 ! somatostatin secretion id: CL:0000173 name: pancreatic D cell def: "A D cell located in the pancreas. Peripherally placed within the islets like type A cells; contains somatostatin." [FMA:0517223651, GOC:tfm] +subset: cellxgene_subset subset: human_reference_atlas synonym: "D-cell of pancreatic islet" EXACT [] synonym: "delta cell of islet" EXACT [] @@ -2389,6 +2466,7 @@ id: CL:0000178 name: Leydig cell def: "A Leydig cell is a testosterone-secreting cell in the interstitial area, between the seminiferous tubules, in the testis." [GOC:tfm, PMID:12050120] comment: Note that the Amphibian Anatomy Ontology (AA) has a class 'leydig cells' but this is unrelated +subset: cellxgene_subset synonym: "interstitial cell" BROAD [] synonym: "interstitial cell of Leydig" EXACT [] xref: BTO:0000755 @@ -2423,7 +2501,7 @@ id: CL:0000181 name: obsolete metabolising cell def: "A cell whose primary function is intermediary metabolism." [FB:ma] comment: Removing this grouping class, because the groupings are incomplete and too hard to maintain. -property_value: seeAlso "https://github.com/obophenotype/cell-ontology/issues/720" xsd:string +relationship: term_tracker_item https://github.com/obophenotype/cell-ontology/issues/720 is_obsolete: true [Term] @@ -2431,6 +2509,7 @@ id: CL:0000182 name: hepatocyte def: "The main structural component of the liver. They are specialized epithelial cells that are organized into interconnected plates called lobules. Majority of cell population of liver, polygonal in shape, arranged in plates or trabeculae between sinusoids; may have single nucleus or binucleated." [GOC:tfm, http://en.wikipedia.org/wiki/Hepatocyte, ISBN:0412046911, MESH:D022781, PMID:19717280] comment: Hepatocytes are reportedly MHC Class I-positive and MHC Class II-positive. +subset: cellxgene_subset subset: human_reference_atlas xref: BTO:0000575 xref: CALOHA:TS-0454 @@ -2447,12 +2526,14 @@ relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens id: CL:0000183 name: contractile cell def: "A cell whose primary function is to shorten." [FB:ma] +subset: cellxgene_subset is_a: CL:0000000 ! cell [Term] id: CL:0000185 name: myoepithelial cell def: "Contractile cells resembling smooth muscle cells that are present in glands, notably the mammary gland, and aid in secretion. This cell has long weaving dendritic processes containing myofilament." [GOC:tfm, ISBN:0721662544] +subset: cellxgene_subset synonym: "basket epithelial cell" EXACT [] synonym: "myoepitheliocyte" EXACT [] xref: BTO:0002309 @@ -2467,6 +2548,7 @@ id: CL:0000186 name: myofibroblast cell def: "An animal cell that has characteristics of both a fibroblast cell and a smooth muscle cell." [GOC:dsd, GOC:tfm, MESH:D058628, PMID:19800625, PMID:20630469, PMID:22387320] comment: Myofibroblasts are alpha-SMA-positive, CD34-negative, CD45-negative. They are reportedly capable of secreting IL-1beta, IL-6, and TNF-alpha. +subset: cellxgene_subset subset: human_reference_atlas synonym: "MFB" EXACT [PMID:8731193] is_a: CL:0000183 ! contractile cell @@ -2477,6 +2559,7 @@ relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens id: CL:0000187 name: muscle cell def: "A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns." [MESH:D032342] +subset: cellxgene_subset synonym: "muscle fiber" EXACT [] synonym: "myocyte" EXACT [] xref: BTO:0000888 @@ -2494,6 +2577,7 @@ property_value: depiction "https://www.swissbiopics.org/api/image/Muscle_cells.s id: CL:0000188 name: cell of skeletal muscle def: "A somatic cell located in skeletal muscle." [GOC:tfm] +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "skeletal muscle cell" EXACT [] @@ -2510,6 +2594,7 @@ relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens id: CL:0000189 name: slow muscle cell def: "A muscle cell that develops tension more slowly than a fast-twitch fiber." [GOC:tfm, ISBN:0323052908] +subset: cellxgene_subset synonym: "slow muscle fiber" RELATED [ISBN:0815316208] is_a: CL:0008046 ! extrafusal muscle fiber relationship: develops_from CL:0000857 ! slow muscle myoblast @@ -2518,6 +2603,7 @@ relationship: develops_from CL:0000857 ! slow muscle myoblast id: CL:0000190 name: fast muscle cell def: "A muscle cell that can develop high tension rapidly. It is usually innervated by a single alpha neuron." [GOC:tfm, ISBN:0323052908] +subset: cellxgene_subset synonym: "glycolytic muscle fiber" EXACT [] is_a: CL:0008046 ! extrafusal muscle fiber relationship: develops_from CL:0000858 ! fast muscle myoblast @@ -2527,6 +2613,7 @@ id: CL:0000192 name: smooth muscle cell alt_id: CL:0000191 def: "A non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels. They develop from specialized myoblasts (smooth muscle myoblast)." [http://en.wikipedia.org/wiki/Smooth_muscle_cell, MESH:D032389, PMID:9315361] +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "myocytes, smooth muscle" EXACT [MESH:D032389] @@ -2680,6 +2767,7 @@ is_a: CL:0000206 ! chemoreceptor cell id: CL:0000209 name: taste receptor cell def: "A specialized cell involved in gustatory sensory perception." [GOC:tfm, ISBN:0618947256] +subset: cellxgene_subset synonym: "taste bud cell" EXACT [] xref: FMA:67910 is_a: CL:0000098 ! sensory epithelial cell @@ -2693,6 +2781,7 @@ relationship: capable_of GO:0050912 ! detection of chemical stimulus involved in id: CL:0000210 name: photoreceptor cell def: "A cell specialized to detect and transduce light." [MESH:D010786] +subset: cellxgene_subset xref: BTO:0001060 xref: CALOHA:TS-0868 xref: FMA:86740 @@ -2743,6 +2832,7 @@ is_a: CL:0000000 ! cell id: CL:0000216 name: Sertoli cell def: "A supporting cell projecting inward from the basement membrane of seminiferous tubules. They surround and nourish the developing male germ cells and secrete androgen binding protein. Their tight junctions with the spermatogonia and spermatocytes provide a blood-testis barrier." [MESH:D012708] +subset: cellxgene_subset xref: BTO:0001238 xref: CALOHA:TS-0922 xref: FMA:72298 @@ -2803,6 +2893,7 @@ relationship: part_of UBERON:0000924 ! ectoderm id: CL:0000222 name: mesodermal cell def: "A cell of the middle germ layer of the embryo." [MESH:D008648] +subset: cellxgene_subset synonym: "mesoblast" EXACT [] synonym: "mesoderm cell" EXACT [] xref: FMA:72554 @@ -2897,6 +2988,7 @@ id: CL:0000232 name: erythrocyte def: "A red blood cell. In mammals, mature erythrocytes are biconcave disks containing hemoglobin whose function is to transport oxygen." [GOC:tfm, MESH:D004912] subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "RBC" EXACT [] synonym: "red blood cell" EXACT [] @@ -2924,6 +3016,7 @@ name: platelet def: "A non-nucleated disk-shaped cell formed by extrusion from megakaryocytes, found in the blood of all mammals, and mainly involved in blood coagulation." [GOC:add, GOC:dsd, GOC:tfm, http://en.wikipedia.org/wiki/Platelet, MESH:D001792, PMID:11110672, PMID:16987572, PMID:17204662, PMID:17479180, PMID:20414831] comment: Platelets are reportedly CCR1-positive, CCR2-negative, CCR3-positive, CCR4-positive, CCR5-negative, CCR6-negative, CCR7-negative, CCR8-negative, CCR9-negative, CCR10-negative, CD16-positive, CD23-positive, CD32-positive, CD40-positive, CD41-positive CD42-positive, CD61-positive, CD62P-positive, CD64-positive, CD89-positive, CD102-positive, CD147-positive (activated platelets), CD154-positive (activated platelets), CD162-positive, CD209, CD282-positive, CD284-positive, CD289-positive, CD181-negative, CD182-negative, CD183-negative, CD184-positive, CLEC2-positive, GPVI-positive, JAMC-positive, PAR1-positive, PAR2-negative, PAR3-positive, PAR4-positive, TSP1-positive, and TXA2R-positive. Platelets can reportedly produce CCL2, CCL3, CCL5, CCL7, CCL17, CD40L, CXCL1, CXCL4, CXCL4L1, CXCL5, CXCL7, CXCL8, CXCL12, EGF, factor V, factor VII, factor XI, factor XIII, bFGF, histamine, IGF-1, IL-1beta, PAI-1, PDGF, plasminogen, protein S, serotonin, TGF-beta, TFPI, VEGF, and vWF. subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "anucleate thrombocyte" EXACT [] synonym: "blood platelet" EXACT [] @@ -2944,6 +3037,7 @@ relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens id: CL:0000234 name: phagocyte def: "Any cell capable of ingesting particulate matter via phagocytosis." [GOC:add, ISBN:0721601464] +subset: cellxgene_subset xref: BTO:0001044 xref: FMA:83806 xref: MESH:D010586 @@ -2960,6 +3054,7 @@ name: macrophage def: "A mononuclear phagocyte present in variety of tissues, typically differentiated from monocytes, capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells." [GO_REF:0000031, GOC:add, GOC:tfm, PMID:16213494, PMID:1919437] comment: Morphology: Diameter 30_M-80 _M, abundant cytoplasm, low N/C ratio, eccentric nucleus. Irregular shape with pseudopods, highly adhesive. Contain vacuoles and phagosomes, may contain azurophilic granules; markers: Mouse & Human: CD68, in most cases CD11b. Mouse: in most cases F4/80+; role or process: immune, antigen presentation, & tissue remodelling; lineage: hematopoietic, myeloid. subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "histiocyte" EXACT [] @@ -2984,6 +3079,7 @@ id: CL:0000236 name: B cell def: "A lymphocyte of B lineage that is capable of B cell mediated immunity." [GO_REF:0000031, GOC:add, GOC:tfm, ISBN:0781735149] subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "B lymphocyte" EXACT [] @@ -3039,6 +3135,7 @@ relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens id: CL:0000242 name: Merkel cell def: "A modified epidermal cell located in the stratum basale. They are found mostly in areas where sensory perception is acute. Merkel cells are closely associated with an expanded terminal bulb of an afferent myelinated nerve fiber." [MESH:D018862] +subset: cellxgene_subset subset: human_reference_atlas synonym: "Merkel's cell" EXACT [] xref: FMA:70548 @@ -3053,7 +3150,7 @@ id: CL:0000243 name: obsolete glial cell (sensu Vertebrata) def: "A non-neuronal cell of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu. Form the myelin insulation of nervous pathways, guide neuronal migration during development, and exchange metabolites with neurons. Neuroglia have high-affinity transmitter uptake systems, voltage-dependent and transmitter-gated ion channels, and can release transmitters, but their role in signaling (as in many other functions) is unclear." [MESH:D009457] comment: This is a grouping class that is no longer needed or wanted. -property_value: seeAlso "https://github.com/obophenotype/cell-ontology/issues/715" xsd:string +relationship: term_tracker_item https://github.com/obophenotype/cell-ontology/issues/715 is_obsolete: true [Term] @@ -3128,6 +3225,7 @@ replaced_by: PO:0020048 [Term] id: CL:0000253 name: eurydendroid cell +subset: cellxgene_subset is_a: CL:0000527 ! efferent neuron [Term] @@ -3141,6 +3239,7 @@ replaced_by: PO:0020094 [Term] id: CL:0000255 name: eukaryotic cell +subset: cellxgene_subset xref: MESH:D005057 is_a: CL:0000000 ! cell intersection_of: CL:0000000 ! cell @@ -3349,6 +3448,7 @@ is_a: CL:0000521 ! fungal cell [Term] id: CL:0000287 name: eye photoreceptor cell +subset: cellxgene_subset subset: eye_upper_slim subset: human_reference_atlas is_a: CL:0000210 ! photoreceptor cell @@ -3542,6 +3642,7 @@ name: keratinocyte alt_id: CL:0002185 def: "An epidermal cell which synthesizes keratin and undergoes a characteristic change as it moves upward from the basal layers of the epidermis to the cornified (horny) layer of the skin. Successive stages of differentiation of the keratinocytes forming the epidermal layers are basal cell, spinous or prickle cell, and the granular cell." [GOC:dsd, http://en.wikipedia.org/wiki/Keratinocyte, MESH:D015603, PMID:15582983, PMID:15749908, PMID:19727116] comment: Keratinocytes are reportedly CDw210a-negative, CDw210b-positive, CD281-positive, CD282-positive, CD285-positive, IL22Ra1-positive, Human keratinocytes are reportedly capable of secreting BD-2, BD-3, hCAP-18, CXCL1, CXCL5, CXCL8, elafin, MMP-3, NGAL, PDGF-A, S100A7, S100A8, and S100A9. Transcription factors: STAT3-positive. +subset: cellxgene_subset subset: human_reference_atlas synonym: "keratinized cell of epidermis" EXACT [] synonym: "malpighian cell" EXACT [] @@ -3562,6 +3663,7 @@ relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens id: CL:0000313 name: serous secreting cell def: "Columnar glandular cell with irregular nucleus, copious granular endoplasmic reticulum and supranuclear granules. Secretes a watery fluid containing proteins known as serous fluid." [GOC:tfm, ISBN:0517223651, ISBN:0721662544] +subset: cellxgene_subset synonym: "serous cell" EXACT [] xref: BTO:0003687 xref: FMA:62511 @@ -3608,6 +3710,7 @@ is_a: CL:0000150 ! glandular epithelial cell [Term] id: CL:0000319 name: mucus secreting cell +subset: cellxgene_subset synonym: "mucous cell" EXACT [] xref: BTO:0003689 is_a: CL:0000159 ! seromucus secreting cell @@ -3627,7 +3730,7 @@ replaced_by: PO:0000431 [Term] id: CL:0000321 name: obsolete seminal fluid secreting cell -comment: https://github.com/obophenotype/cell-ontology/issues/1149 +relationship: term_tracker_item https://github.com/obophenotype/cell-ontology/issues/1149 is_obsolete: true replaced_by: CL:0000151 consider: CL:1001597 @@ -3636,6 +3739,7 @@ consider: CL:1001597 id: CL:0000322 name: pneumocyte def: "An epithelial cell that lines the peripheral gas exchange region of the lungs of air-breathing vertebrates." [GOC:tfm, PMID:20054144] +subset: cellxgene_subset synonym: "alveolar epithelial cell" EXACT [] synonym: "pneumonocyte" EXACT [] xref: BTO:0000395 @@ -3923,6 +4027,7 @@ relationship: part_of UBERON:0004590 ! sphincter muscle id: CL:0000359 name: vascular associated smooth muscle cell def: "A smooth muscle cell associated with the vasculature." [GOC:dsd, GOC:tfm] +subset: cellxgene_subset subset: human_reference_atlas synonym: "vascular smooth muscle cell" EXACT [] synonym: "VSMC" EXACT [] @@ -3952,6 +4057,7 @@ id: CL:0000362 name: epidermal cell alt_id: CL:1000396 def: "An epithelial cell of the integument (the outer layer of an organism)." [Flybase:dsj, MA:ma] +subset: cellxgene_subset synonym: "cell of epidermis" EXACT [FMA:62411] synonym: "epithelial cell of skin" NARROW [FMA:62411] xref: BTO:0001470 @@ -4095,7 +4201,8 @@ is_a: CL:0000378 ! supporting cell (sensu Nematoda and Protostomia) [Term] id: CL:0000381 name: obsolete neurosecretory neuron -comment: https://github.com/obophenotype/cell-ontology/issues/1784\n'neuroendocrine cell' (which has exact synonym "neurosecretory cell") and 'neurosecretory neuron' may all refer to the same cell type. +comment: 'neuroendocrine cell' (which has exact synonym "neurosecretory cell") and 'neurosecretory neuron' may all refer to the same cell type. +relationship: term_tracker_item https://github.com/obophenotype/cell-ontology/issues/1784 is_obsolete: true replaced_by: CL:0000165 @@ -4147,6 +4254,7 @@ relationship: only_in_taxon NCBITaxon:6656 ! Arthropoda id: CL:0000388 name: tendon cell def: "An elongated fibrocyte that is part of a tendon. The cytoplasm is stretched between the collagen fibres of the tendon. They have a central cell nucleus with a prominent nucleolus. Tendon cells have a well-developed rough endoplasmic reticulum and they are responsible for synthesis and turnover of tendon fibres and ground substance." [GOC:NV, GOC:tfm, PMID:957445] +subset: cellxgene_subset synonym: "muscle attachment cell" EXACT [] synonym: "tenocyte" RELATED [] is_a: CL:0000135 {is_inferred="true"} ! fibrocyte @@ -4171,7 +4279,7 @@ relationship: never_in_taxon NCBITaxon:33511 ! Deuterostomia id: CL:0000391 name: obsolete podocyte (sensu Diptera) comment: Obsoleted as podocytes are not a distinct cell type from plasmatocytes. -property_value: term_tracker_item "https://github.com/obophenotype/cell-ontology/issues/1949" xsd:string +relationship: term_tracker_item https://github.com/obophenotype/cell-ontology/issues/1949 is_obsolete: true replaced_by: CL:0000394 @@ -4192,6 +4300,7 @@ is_a: CL:0000211 ! electrically active cell id: CL:0000394 name: plasmatocyte def: "A phagocytic hemocyte, responsible for the engulfment of small particles, microbes, and apoptotic tissue debris. It may also secretes antimicrobial peptides and contribute to the production and secretion of proteins of the hemolymph." [https://doi.org/10.1016/B978-012369493-5.50008-0] +subset: cellxgene_subset synonym: "macrophage" RELATED [] xref: FBbt:00001685 is_a: CL:0000387 ! hemocyte (sensu Arthropoda) @@ -4214,6 +4323,7 @@ is_a: CL:0000387 ! hemocyte (sensu Arthropoda) [Term] id: CL:0000397 name: ganglion interneuron +subset: cellxgene_subset is_a: CL:0000099 {is_inferred="true"} ! interneuron intersection_of: CL:0000099 ! interneuron intersection_of: RO:0002100 UBERON:0000045 ! has soma location ganglion @@ -4224,7 +4334,7 @@ id: CL:0000398 name: obsolete polygonal cell comment: Obsoleted as this is actually the same thing as prohemocytes. xref: FBbt:00001691 -property_value: term_tracker_item "https://github.com/obophenotype/cell-ontology/issues/1949" xsd:string +relationship: term_tracker_item https://github.com/obophenotype/cell-ontology/issues/1949 is_obsolete: true replaced_by: CL:0000385 @@ -4245,7 +4355,7 @@ replaced_by: PO:0000332 id: CL:0000401 name: obsolete macrophage (sensu Diptera) comment: Obsoleted as plasmatocytes are the macrophages (phagocytic cells) of Diptera. -property_value: term_tracker_item "https://github.com/obophenotype/cell-ontology/issues/1949" xsd:string +relationship: term_tracker_item https://github.com/obophenotype/cell-ontology/issues/1949 is_obsolete: true replaced_by: CL:0000394 @@ -4271,7 +4381,7 @@ is_a: CL:0000211 ! electrically active cell id: CL:0000405 name: obsolete neuroepidermoblast comment: Obsoleted as the term seems completely unused in the literature. -property_value: term_tracker_item "https://github.com/FlyBase/drosophila-anatomy-developmental-ontology/issues/1621" xsd:string +relationship: term_tracker_item https://github.com/FlyBase/drosophila-anatomy-developmental-ontology/issues/1621 is_obsolete: true [Term] @@ -4425,7 +4535,7 @@ is_a: CL:0000658 ! cuticle secreting cell id: CL:0000426 name: obsolete scaffold cell comment: This is a cell used in tissue engineering and is out of scope for CL. -property_value: seeAlso "https://github.com/obophenotype/cell-ontology/issues/708" xsd:string +relationship: term_tracker_item https://github.com/obophenotype/cell-ontology/issues/708 is_obsolete: true [Term] @@ -4471,6 +4581,7 @@ relationship: develops_from CL:0005001 ! iridoblast id: CL:0000432 name: reticular cell def: "A fibroblast that synthesizes collagen and uses it to produce reticular fibers, thus providing structural support. Reticular cells are found in many organs, including the spleen, lymph nodes and kidneys. Subtypes of reticular cells include epithelial, mesenchymal, and fibroblastic reticular cells. Fibroblastic reticular cells are involved in directing B cells and T cells to specific regions within a tissue, whereas epithelial and mesenchymal reticular cells are associated with certain areas of the brain." [GOC:tfm, http://en.wikipedia.org/wiki/Reticular_cell, ISBN:0517223651] +subset: cellxgene_subset subset: human_reference_atlas synonym: "reticulum cell" EXACT [] xref: FMA:62877 @@ -4566,6 +4677,7 @@ id: CL:0000442 name: follicular dendritic cell def: "A cell with extensive dendritic processes found in the B cell areas (primary follicles and germinal centers) of lymphoid tissue. They are unrelated to the dendritic cell associated with T cells. Follicular dendritic cells have Fc receptors and C3b receptors, but unlike other dendritic cells, they do not process or present antigen in a way that allows recognition by T cells. Instead, they hold antigen in the form of immune complexes on their surfaces for long periods and can present antigen to B cells during an immune response." [ISBN:127520252] comment: Due to its unique lineage and distinct function, this is not a type of dendritic cell; CL:0000451. +subset: cellxgene_subset subset: human_reference_atlas xref: BTO:0004267 xref: FMA:83037 @@ -4644,6 +4756,7 @@ relationship: part_of UBERON:0001348 ! brown adipose tissue id: CL:0000451 name: dendritic cell def: "A cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation. These cells are lineage negative (CD3-negative, CD19-negative, CD34-negative, and CD56-negative)." [GOC:add, ISBN:0781735149] +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "interdigitating cell" RELATED [] @@ -4688,6 +4801,7 @@ id: CL:0000453 name: Langerhans cell def: "Langerhans cell is a conventional dendritic cell that has plasma membrane part CD207. A Langerhans cell is a stellate dendritic cell of myeloid origin, that appears clear on light microscopy and has a dark-staining, indented nucleus and characteristic inclusions (Birbeck granules) in the cytoplasm; Langerhans cells are found principally in the stratum spinosum of the epidermis, but they also occur in other stratified epithelia and have been identified in the lung, lymph nodes, spleen, and thymus." [GO_REF:0000031, GOC:add, GOC:amm, ISBN:0721601464, ISBN:0781735149, PMCID:PMC2346585, PMID:17850486] comment: Originally described in the dendritic cell ontology (DC_CL:0000021 )(PMID:19243617). These cells are also CD1a-high, CD14-negative, CD207-positive (langerin), CD324-positive (E-cadherin), and DCIR-positive. They reside in the epidermis. +subset: cellxgene_subset subset: human_reference_atlas synonym: "LC" EXACT [] xref: BTO:0000705 @@ -5021,6 +5135,7 @@ is_obsolete: true id: CL:0000492 name: CD4-positive helper T cell def: "A CD4-positive, alpha-beta T cell that cooperates with other lymphocytes via direct contact or cytokine release to initiate a variety of immune functions." [GO_REF:0000031, GOC:add, GOC:pam, GOC:tfm, ISBN:0781735149, MESH:D006377] +subset: cellxgene_subset subset: human_reference_atlas synonym: "CD4-positive helper T lymphocyte" EXACT [] synonym: "CD4-positive helper T-cell" EXACT [] @@ -5074,6 +5189,7 @@ is_a: CL:0000490 ! photopic photoreceptor cell id: CL:0000498 name: inhibitory interneuron def: "An interneuron (also called relay neuron, association neuron or local circuit neuron) is a multipolar neuron which connects afferent neurons and efferent neurons in neural pathways. Like motor neurons, interneuron cell bodies are always located in the central nervous system (CNS)." [GOC:tfm, http://en.wikipedia.org/wiki/Interneuron] +subset: cellxgene_subset xref: FMA:84776 is_a: CL:0000099 ! interneuron @@ -5081,6 +5197,7 @@ is_a: CL:0000099 ! interneuron id: CL:0000499 name: stromal cell def: "A connective tissue cell of an organ found in the loose connective tissue. These are most often associated with the uterine mucosa and the ovary as well as the hematopoietic system and elsewhere." [GOC:tfm, MESH:D017154] +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas xref: BTO:0002064 @@ -5099,6 +5216,7 @@ is_a: CL:0000066 ! epithelial cell id: CL:0000501 name: granulosa cell def: "A supporting cell for the developing female gamete in the ovary of mammals. They develop from the coelomic epithelial cells of the gonadal ridge. Granulosa cells form a single layer around the mammalian oocyte in the primordial ovarian follicle and advance to form a multilayered cumulus oophorus surrounding the ovum in the Graafian follicle. The major functions of granulosa cells include the production of steroids and LH receptors." [MESH:D006107] +subset: cellxgene_subset synonym: "granulosa cell of ovary" EXACT [] xref: BTO:0000542 xref: CALOHA:TS-0729 @@ -5110,6 +5228,7 @@ is_a: CL:0002174 ! follicular cell of ovary id: CL:0000502 name: type D enteroendocrine cell def: "A cell found throughout the gastrointestinal tract and in the pancreas. They secrete somatostatin in both an endocrine and paracrine manner. Somatostatin inhibits gastrin, cholecystokinin, insulin, glucagon, pancreatic enzymes, and gastric hydrochloric acid. A variety of substances which inhibit gastric acid secretion (vasoactive intestinal peptide, calcitonin gene-related peptide, cholecystokinin, beta-adrenergic agonists, and gastric inhibitory peptide) are thought to act by releasing somatostatin." [MESH:D019864] +subset: cellxgene_subset synonym: "D cell" EXACT [] xref: FMA:62935 is_a: CL:0000164 ! enteroendocrine cell @@ -5119,6 +5238,7 @@ is_a: CL:0000172 ! somatostatin secreting cell id: CL:0000503 name: theca cell def: "A flattened stroma cell forming a sheath or theca outside the basal lamina lining the mature ovarian follicle. Thecal interstitial or stromal cells are steroidogenic, and produce primarily androgens which serve as precusors of estrogens in the granulosa cells." [MESH:D013799] +subset: cellxgene_subset subset: human_reference_atlas xref: BTO:0002850 is_a: CL:0000593 ! androgen secreting cell @@ -5158,6 +5278,7 @@ is_a: CL:0000167 ! peptide hormone secreting cell id: CL:0000508 name: type G enteroendocrine cell def: "An endocrine cell found in the pyloric gland mucosa (antral mucosa) of the stomach of mammals and responsible for the secretion of gastrin and enkephalin. Most abundant in pyloric antrum, pyramidal in form with a narrow apex bearing long microvilli." [GOC:tfm, ISBN:0517223651, MESH:D019863] +subset: cellxgene_subset synonym: "G cell" EXACT [] xref: BTO:0004108 xref: FMA:67609 @@ -5179,6 +5300,7 @@ relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens id: CL:0000510 name: paneth cell def: "An epithelial cell found in the basal part of the intestinal glands (crypts of Lieberkuhn) including the appendix. Paneth cells synthesize and secrete lysozyme and cryptdins. Numerous in the deeper parts of the intestinal crypts, particularly in the duodenum, rich in zinc, contain large acidophilic granules, with irregular apical microvilli and prominent membrane-bound vacuoles containing matrix." [GOC:tfm, ISBN:0517223651, MESH:D019879, PMID:29184701, PMID:32308658] +subset: cellxgene_subset xref: BTO:0000993 xref: FMA:62897 is_a: CL:0000150 {is_inferred="true"} ! glandular epithelial cell @@ -5203,27 +5325,29 @@ id: CL:0000513 name: cardiac muscle myoblast alt_id: CL:0000714 def: "A precursor cell destined to differentiate into cardiac muscle cell." [GOC:tfm, MESH:D032386] +subset: cellxgene_subset synonym: "cardiac muscle progenitor cell" EXACT [] synonym: "cardiomyocyte progenitor cell" EXACT [] xref: FMA:84797 is_a: CL:0002494 ! cardiocyte is_a: CL:0010021 ! cardiac myoblast intersection_of: CL:0000056 ! myoblast +intersection_of: develops_into CL:0000746 ! cardiac muscle cell intersection_of: part_of UBERON:0001133 ! cardiac muscle tissue -intersection_of: RO:0002203 CL:0000746 ! develops into cardiac muscle cell relationship: part_of UBERON:0001133 ! cardiac muscle tissue [Term] id: CL:0000514 name: smooth muscle myoblast def: "A precursor cell destined to differentiate into smooth muscle myocytes." [GOC:tfm, MESH:D032390] +subset: cellxgene_subset synonym: "myoblast, smooth muscle" EXACT [MESH:D032390] synonym: "satellite cell" RELATED [] xref: FMA:84798 is_a: CL:0000056 ! myoblast intersection_of: CL:0000056 ! myoblast -intersection_of: RO:0002203 CL:0000192 ! develops into smooth muscle cell -relationship: RO:0002203 CL:0000192 ! develops into smooth muscle cell +intersection_of: develops_into CL:0000192 ! smooth muscle cell +relationship: develops_into CL:0000192 ! smooth muscle cell [Term] id: CL:0000515 @@ -5234,9 +5358,9 @@ xref: FMA:84799 is_a: CL:0000056 ! myoblast is_a: CL:0011026 ! progenitor cell intersection_of: CL:0000056 ! myoblast -intersection_of: RO:0002203 CL:0008002 ! develops into skeletal muscle fiber +intersection_of: develops_into CL:0008002 ! skeletal muscle fiber relationship: develops_from CL:0000355 ! multi-potent skeletal muscle stem cell -relationship: RO:0002203 CL:0008002 ! develops into skeletal muscle fiber +relationship: develops_into CL:0008002 ! skeletal muscle fiber [Term] id: CL:0000516 @@ -5313,6 +5437,7 @@ is_a: CL:0000371 ! protoplast id: CL:0000525 name: syncytiotrophoblast cell def: "A cell from the outer syncytial layer of the trophoblast of an early mammalian embryo, directly associated with the maternal blood supply. It secretes hCG in order to maintain progesterone secretion and sustain a pregnancy." [GOC:tfm, ISBN:0323052908] +subset: cellxgene_subset subset: human_reference_atlas synonym: "plasmidotrophoblast cell" RELATED [] synonym: "syncytial trophoblast cell" EXACT [PMID:11787150] @@ -5354,6 +5479,7 @@ is_a: CL:0000540 ! neuron [Term] id: CL:0000529 name: pigmented epithelial cell +subset: cellxgene_subset is_a: CL:0000710 ! neurecto-epithelial cell [Term] @@ -5368,6 +5494,7 @@ relationship: only_in_taxon NCBITaxon:32443 {IAO:0000233="https://github.com/obo id: CL:0000531 name: primary sensory neuron (sensu Teleostei) def: "A primary neuron (sensu Teleostei) that has a sensory function." [PMID:1842357] +subset: cellxgene_subset is_a: CL:0000101 ! sensory neuron is_a: CL:0000530 ! primary neuron (sensu Teleostei) intersection_of: CL:0000101 ! sensory neuron @@ -5434,6 +5561,7 @@ id: CL:0000540 name: neuron def: "The basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system." [http://en.wikipedia.org/wiki/Neuron, MESH:D009474] comment: These cells are also reportedly CD4-negative and CD200-positive. They are also capable of producing CD40L and IFN-gamma. +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "nerve cell" EXACT [] @@ -5467,6 +5595,7 @@ id: CL:0000542 name: lymphocyte def: "A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin." [GOC:add, ISBN:0683073696, ISBN:0781735149] comment: Editors note: consider adding taxon constraint to vertebrata (PMID:18025161) +subset: cellxgene_subset subset: human_reference_atlas xref: BTO:0000775 xref: CALOHA:TS-0583 @@ -5477,13 +5606,13 @@ is_a: CL:0000842 ! mononuclear cell is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000738 ! leukocyte intersection_of: bearer_of PATO:0001407 ! mononucleate +intersection_of: bearer_of PATO:0040072 ! high nuclear/cytoplasmic ratio intersection_of: has_part CL:0017500 ! neutrophillic cytoplasm -intersection_of: has_part CL:0017505 ! increased nucleus size intersection_of: has_part GO:0000792 ! heterochromatin disjoint_from: CL:0000766 ! myeloid leukocyte +relationship: bearer_of PATO:0040072 ! high nuclear/cytoplasmic ratio relationship: develops_from CL:0000051 ! common lymphoid progenitor relationship: has_part CL:0017500 ! neutrophillic cytoplasm -relationship: has_part CL:0017505 ! increased nucleus size relationship: has_part GO:0000792 ! heterochromatin relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens @@ -5505,6 +5634,7 @@ id: CL:0000545 name: T-helper 1 cell def: "A CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive, CXCR3-positive, CCR6-negative, and is capable of producing interferon-gamma." [GO_REF:0000031, GOC:add, GOC:pam, GOC:tfm, PMID:19375293, PMID:20303875, PMID:22343568] comment: This cell type is compatible with the HIPC Lyoplate markers for 'Th1 CD4+ T cell', but its logical definition includes additional known characteristics of T-helper 1 T cells. +subset: cellxgene_subset subset: human_reference_atlas synonym: "helper T cell type 1" EXACT [] synonym: "T helper cells type 1" EXACT [PMID:9419219] @@ -5534,6 +5664,7 @@ id: CL:0000546 name: T-helper 2 cell def: "A CD4-positive, alpha-beta T cell that has the phenotype GATA-3-positive, CXCR3-negative, CCR6-negative, and is capable of producing interleukin-4." [GO_REF:0000031, GOC:add, GOC:pam, GOC:tfm, PMID:19375293, PMID:20103781, PMID:22343568] comment: This cell type is compatible with the HIPC Lyoplate markers for 'non-Th1/Th17 CD4+ T cell' (see CL:0001051), but includes the additional necessary and sufficient conditions to allow classification as a T-helper 2 T cell. +subset: cellxgene_subset subset: human_reference_atlas synonym: "helper T cell type 2" EXACT [] synonym: "T helper cells type 2" EXACT [PMID:9419219] @@ -5562,6 +5693,7 @@ id: CL:0000547 name: proerythroblast def: "An immature, nucleated erythrocyte occupying the stage of erythropoeisis that follows formation of erythroid progenitor cells. This cell is CD71-positive, has both a nucleus and a nucleolus, and lacks hematopoeitic lineage markers." [ISBN:0721601464, PMID:1638021] subset: blood_and_immune_upper_slim +subset: cellxgene_subset synonym: "pronormoblast" RELATED [] synonym: "rubriblast" EXACT [ISBN:0721601464] xref: FMA:83518 @@ -5570,6 +5702,7 @@ is_a: CL:0002242 ! nucleate cell is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000764 ! erythroid lineage cell intersection_of: bearer_of PATO:0002505 ! nucleated +intersection_of: bearer_of PATO:0040072 ! high nuclear/cytoplasmic ratio intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M @@ -5582,9 +5715,9 @@ intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell sur intersection_of: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule intersection_of: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G intersection_of: has_part CL:0017503 ! basophilic cytoplasm -intersection_of: has_part CL:0017505 ! increased nucleus size intersection_of: has_part GO:0005730 ! nucleolus intersection_of: RO:0002104 PR:000001945 ! has plasma membrane part transferrin receptor protein 1 +relationship: bearer_of PATO:0040072 ! high nuclear/cytoplasmic ratio relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M @@ -5598,7 +5731,6 @@ relationship: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule relationship: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G relationship: develops_from CL:0000038 ! erythroid progenitor cell relationship: has_part CL:0017503 ! basophilic cytoplasm -relationship: has_part CL:0017505 ! increased nucleus size relationship: has_part GO:0005730 ! nucleolus relationship: RO:0002104 PR:000001945 ! has plasma membrane part transferrin receptor protein 1 @@ -5606,9 +5738,10 @@ relationship: RO:0002104 PR:000001945 ! has plasma membrane part transferrin rec id: CL:0000548 name: obsolete animal cell def: "OBSOLETE. A native cell that is part of some Metazoa." [] -comment: https://github.com/obophenotype/cell-ontology/issues/2124 +subset: cellxgene_subset subset: ubprop:upper_level synonym: "metazoan cell" EXACT [] +relationship: term_tracker_item https://github.com/obophenotype/cell-ontology/issues/2124 property_value: depiction "https://www.swissbiopics.org/api/image/Animal_cells.svg" xsd:anyURI is_obsolete: true replaced_by: CL:0000000 @@ -5682,6 +5815,7 @@ id: CL:0000553 name: megakaryocyte progenitor cell def: "The earliest cytologically identifiable precursor in the thrombocytic series. This cell is capable of endomitosis and lacks expression of hematopoieitic lineage markers (lin-negative)." [GOC:dsd, GOC:tfm, ISBN:0721601464] comment: Lineage negative is described here as CD2-negative, CD3-negative, CD4-negative, CD5-negative, CD8a-negative, CD14-negative, CD19-negative, CD20-negative, CD56-negative, Ly6g-negative, and Ter119-negative. +subset: cellxgene_subset subset: human_reference_atlas synonym: "CFU-Meg" EXACT [PMID:11722431, PMID:12482498] synonym: "colony-forming unit-megakaryocyte" EXACT [] @@ -5740,6 +5874,7 @@ is_a: CL:0000167 ! peptide hormone secreting cell [Term] id: CL:0000555 name: neuronal brush cell +subset: cellxgene_subset is_a: CL:0000117 ! CNS neuron (sensu Vertebrata) [Term] @@ -5748,6 +5883,7 @@ name: megakaryocyte def: "A large hematopoietic cell (50 to 100 micron) with a lobated nucleus. Once mature, this cell undergoes multiple rounds of endomitosis and cytoplasmic restructuring to allow platelet formation and release." [http://en.wikipedia.org/wiki/Megakaryocyte, ISBN:0721601464, MESH:D008533, PMID:31043076] comment: Megakaryocytes are reportedly CD181-positive and CD182-positive. subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "megacaryocyte" EXACT [] synonym: "megalocaryocyte" EXACT [] @@ -5766,6 +5902,7 @@ id: CL:0000557 name: granulocyte monocyte progenitor cell def: "A hematopoietic progenitor cell that is committed to the granulocyte and monocyte lineages. These cells are CD123-positive, and do not express Gata1 or Gata2 but do express C/EBPa, and Pu.1." [GO_REF:0000031, GOC:amm, GOC:dsd, GOC:tfm, http://en.wikipedia.org/wiki/CFU-GM, http://www.copewithcytokines.de, ISBN:0721601464, MESH:D055014, PMCID:PMC2213186, PMCID:PMC548021, PMID:16551251, PMID:16647566] comment: Originally described in the dendritic cell ontology (DC_CL:0000042)(PMID:19243617). GMPs are reportedly CD16-positive, CD32-positive, CD34-positive, CD38-positive, CD45RA-positive, CD110-negative, CD117-positive, CD123-positive, and SCA1-negative. +subset: cellxgene_subset subset: human_reference_atlas synonym: "CFU-C , Colony forming unit in culture" BROAD [http://www.copewithcytokines.de] synonym: "CFU-GM" RELATED OMO:0003000 [ISBN:0721601464, PMCID:PMC2213186, PMCID:PMC548021] @@ -5802,6 +5939,7 @@ id: CL:0000558 name: reticulocyte def: "An immature erythrocyte that changes the protein composition of its plasma membrane by exosome formation and extrusion. The types of protein removed differ between species though removal of the transferrin receptor is apparent in mammals and birds." [GOC:add, GOC:tfm, PMID:15946868, PMID:2037622] subset: blood_and_immune_upper_slim +subset: cellxgene_subset xref: BTO:0001173 xref: CALOHA:TS-0864 xref: MESH:D012156 @@ -5841,6 +5979,7 @@ id: CL:0000559 name: promonocyte def: "A precursor in the monocytic series, being a cell intermediate in development between the monoblast and monocyte. This cell is CD11b-positive and has fine azurophil granules." [GOC:tfm, ISBN:0721601464] comment: Morphology: Mononuclear cell, diameter 14-18 _M, fine azurophilic granules; markers: CD11b (shared with many other myeloid cells); location: Adult: bone marrow; Fetal: Liver, Yolk Sac; role or process: hematopoiesis, monocyte development; lineage: hematopoietic, myeloid. +subset: cellxgene_subset subset: human_reference_atlas xref: BTO:0004657 xref: FMA:83551 @@ -5893,6 +6032,7 @@ relationship: RO:0002104 PR:000001580 ! has plasma membrane part fMet-Leu-Phe re id: CL:0000561 name: amacrine cell def: "Interneuron of the vertebrate retina. They integrate, modulate, and interpose a temporal domain in the visual message presented to the retinal ganglion cells, with which they synapse in the inner plexiform layer. They lack large axons." [GOC:tfm, MESH:D025042, WikipediaVersioned:Amacrine_cell&oldid=1023572246] +subset: cellxgene_subset subset: eye_upper_slim subset: human_reference_atlas synonym: "AC" RELATED OMO:0003000 [doi:10.1038/s41598-020-66092-9] @@ -5997,11 +6137,12 @@ is_a: CL:0000165 ! neuroendocrine cell id: CL:0000569 name: cardiac mesenchymal cell def: "A mesenchymal cell found in the developing heart and that develops into some part of the heart. These cells derive from intra- and extra-cardiac sources, including the endocardium, epicardium, neural crest, and second heart field." [PMID:18816864] +subset: cellxgene_subset is_a: CL:0008019 ! mesenchymal cell is_a: CL:2000073 ! migratory cardiac neural crest cell intersection_of: CL:0008019 ! mesenchymal cell -intersection_of: RO:0002203 CL:0002494 ! develops into cardiocyte -relationship: RO:0002203 CL:0002494 ! develops into cardiocyte +intersection_of: develops_into CL:0002494 ! cardiocyte +relationship: develops_into CL:0002494 ! cardiocyte [Term] id: CL:0000570 @@ -6039,6 +6180,7 @@ relationship: develops_from CL:0005003 ! leucoblast id: CL:0000573 name: retinal cone cell def: "One of the two photoreceptor cell types in the vertebrate retina. In cones the photopigment is in invaginations of the cell membrane of the outer segment. Cones are less sensitive to light than rods, but they provide vision with higher spatial and temporal acuity, and the combination of signals from cones with different pigments allows color vision." [MESH:D017949] +subset: cellxgene_subset subset: human_reference_atlas synonym: "cone" RELATED [doi:10.1038/s41598-020-66092-9] xref: BTO:0001036 @@ -6060,6 +6202,7 @@ id: CL:0000575 name: corneal epithelial cell alt_id: CL:1000431 def: "An epithelial cell of the cornea." [GOC:tfm] +subset: cellxgene_subset subset: eye_upper_slim subset: human_reference_atlas synonym: "epithelial cell of cornea" EXACT [FMA:70551] @@ -6079,6 +6222,7 @@ name: monocyte def: "Myeloid mononuclear recirculating leukocyte that can act as a precursor of tissue macrophages, osteoclasts and some populations of tissue dendritic cells." [GO_REF:0000031, MESH:D009000] comment: Morphology: Mononuclear cell, diameter, 14 to 20 _M, N/C ratio 2:1-1:1. Nucleus may appear in variety of shapes: round, kidney, lobulated, or convoluted. Fine azurophilic granules present; markers: CD11b (shared with other myeloid cells), human: CD14, mouse: F4/80-mid,GR1-low; location: Blood, but can be recruited into tissues; role or process: immune & tissue remodelling; lineage: hematopoietic, myeloid. subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas xref: BTO:0000876 @@ -6103,6 +6247,7 @@ id: CL:0000577 name: type EC enteroendocrine cell alt_id: CL:0002065 def: "A subtype of enteroendocrine cells found in the gastrointestinal mucosa, particularly in the glands of pyloric antrum; duodenum; and ileum. These cell type secretes serotonin and some neurotransmitters including enkephalins and substance P. Their secretory granules stain readily with silver (argentaffin stain)." [PMID:9505449] +subset: cellxgene_subset subset: human_reference_atlas synonym: "argentaffin cell" EXACT [] synonym: "enterochromaffin cell" EXACT [] @@ -6254,6 +6399,7 @@ id: CL:0000583 name: alveolar macrophage def: "A tissue-resident macrophage found in the alveoli of the lungs. Ingests small inhaled particles resulting in degradation and presentation of the antigen to immunocompetent cells. Markers include F4/80-positive, CD11b-/low, CD11c-positive, CD68-positive, sialoadhesin-positive, dectin-1-positive, MR-positive, CX3CR1-negative." [GO_REF:0000031, GOC:ana, GOC:dsd, GOC:tfm, MESH:D016676] comment: Markers: Mouse: F4/80mid, CD11b-/low, CD11c+, CD68+, sialoadhesin+, dectin-1+, MR+, CX3CR1-. +subset: cellxgene_subset subset: human_reference_atlas synonym: "dust cell" EXACT [] synonym: "MF.Lu" RELATED [] @@ -6289,6 +6435,7 @@ relationship: RO:0015016 PR:000001012 ! has low plasma membrane amount integrin id: CL:0000584 name: enterocyte def: "An epithelial cell that has its apical plasma membrane folded into microvilli to provide ample surface for the absorption of nutrients from the intestinal lumen." [SANBI:mhl] +subset: cellxgene_subset subset: human_reference_atlas synonym: "differentiated enterocyte" NARROW [https://orcid.org/0000-0001-9610-7627, PMID:33290721] synonym: "mature enterocyte" NARROW [https://orcid.org/0000-0001-9610-7627, PMID:33290721] @@ -6311,6 +6458,7 @@ is_obsolete: true id: CL:0000586 name: germ cell def: "The reproductive cell in multicellular organisms." [MESH:D005854] +subset: cellxgene_subset xref: BTO:0000535 xref: NCIT:C12597 xref: VHOG:0001534 @@ -6386,6 +6534,7 @@ id: CL:0000594 name: skeletal muscle satellite cell def: "An elongated, spindle-shaped, cell that is located between the basal lamina and the plasmalemma of a muscle fiber. These cells are mostly quiescent, but upon activation they divide to produce cells that generate new muscle fibers." [GOC:tfm, MESH:D032496, PMID:21849021, PMID:23303905] comment: Skeletal muscle satellite cells are not traditionally referred to as myoblasts. They are a heterogeneous population whose division, following activiation, contributes to the formation of skeletal muscle fibers and to maintenance of the skeletal muscle statelite cell population. +subset: cellxgene_subset is_a: CL:0000188 ! cell of skeletal muscle is_a: CL:0000680 ! muscle precursor cell @@ -6393,6 +6542,7 @@ is_a: CL:0000680 ! muscle precursor cell id: CL:0000595 name: enucleate erythrocyte def: "An erythrocyte lacking a nucleus." [GOC:add, GOC:tfm] +subset: cellxgene_subset synonym: "RBC" RELATED OMO:0003000 [] synonym: "red blood cell" BROAD [] is_a: CL:0000225 ! anucleate cell @@ -6421,6 +6571,7 @@ id: CL:0000598 name: pyramidal neuron def: "Pyramidal neurons have a pyramid-shaped soma with a single axon, a large apical dendrite and multiple basal dendrites. The apex and an apical dendrite typically point toward the pial surface and other dendrites and an axon emerging from the base. The axons may have local collaterals but also project outside their region. Pyramidal neurons are found in the cerebral cortex, the hippocampus, and the amygdala." [GOC:tfm, MESH:D017966] subset: BDS_subset +subset: cellxgene_subset synonym: "projection neuron" EXACT [] synonym: "pyramidal cell" EXACT [] xref: BTO:0003102 @@ -6472,6 +6623,7 @@ is_a: CL:0000600 ! heterokaryon id: CL:0000604 name: retinal rod cell def: "One of the two photoreceptor cell types of the vertebrate retina. In rods the photopigment is in stacks of membranous disks separate from the outer cell membrane. Rods are more sensitive to light than cones, but rod mediated vision has less spatial and temporal resolution than cone vision." [MESH:D017948] +subset: cellxgene_subset subset: human_reference_atlas synonym: "rod" RELATED [doi:10.1038/s41598-020-66092-9] xref: BTO:0001024 @@ -6705,6 +6857,7 @@ is_obsolete: true id: CL:0000617 name: GABAergic neuron def: "A neuron that uses GABA as a vesicular neurotransmitter" [GOC:tfm] +subset: cellxgene_subset synonym: "GABA-ergic neuron" EXACT [] xref: FBbt:00007228 xref: FMA:84788 @@ -6744,6 +6897,7 @@ is_a: CL:0008018 ! somatic muscle myoblast id: CL:0000622 name: acinar cell def: "A secretory cell that is grouped together with other cells of the same type to form grape shaped clusters known as acini (singular acinus)." [GOC:tfm, http://www.copewithcytokines.de] +subset: cellxgene_subset synonym: "acinic cell" EXACT [] synonym: "acinous cell" EXACT [] xref: FMA:83625 @@ -6756,6 +6910,7 @@ relationship: part_of UBERON:0009842 ! glandular acinus id: CL:0000623 name: natural killer cell def: "A lymphocyte that can spontaneously kill a variety of target cells without prior antigenic activation via germline encoded activation receptors and also regulate immune responses via cytokine release and direct contact with other cells." [GOC:add, ISBN:0781735149, PMID:15771571] +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "large granular lymphocyte" BROAD [] @@ -6787,6 +6942,7 @@ relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens id: CL:0000624 name: CD4-positive, alpha-beta T cell def: "A mature alpha-beta T cell that expresses an alpha-beta T cell receptor and the CD4 coreceptor." [GOC:add, ISBN:0781735149] +subset: cellxgene_subset subset: human_reference_atlas synonym: "CD4-positive, alpha-beta T lymphocyte" EXACT [] synonym: "CD4-positive, alpha-beta T-cell" EXACT [] @@ -6804,6 +6960,7 @@ relationship: RO:0002104 PR:000001004 ! has plasma membrane part CD4 molecule id: CL:0000625 name: CD8-positive, alpha-beta T cell def: "A T cell expressing an alpha-beta T cell receptor and the CD8 coreceptor." [GOC:add, GOC:tfm, ISBN:0781735149] +subset: cellxgene_subset subset: human_reference_atlas synonym: "CD8-positive, alpha-beta T lymphocyte" EXACT [] synonym: "CD8-positive, alpha-beta T-cell" EXACT [] @@ -6858,6 +7015,7 @@ is_a: CL:0000325 ! stuff accumulating cell id: CL:0000630 name: supporting cell def: "A cell whose primary function is to support other cell types." [FB:ma, GOC:tfm] +subset: cellxgene_subset synonym: "supportive cell" EXACT [] xref: BTO:0002315 is_a: CL:0000000 ! cell @@ -6873,6 +7031,7 @@ id: CL:0000632 name: hepatic stellate cell def: "A cell that is found in the perisinusoidal space of the liver that is capable of multiple roles including storage of retinol, presentation of antigen to T cells (including CD1d-restricted NKT cells), and upon activation, production of extracellular matrix components that can contribute to liver fibrosis. This activated state has a myofibroblast-like phenotype, though it's not clear in the literature if this is terminally differentiated. This cell type comprises approximately 8-15% of total cells in the liver." [GOC:dsd, http://en.wikipedia.org/wiki/Hepatic_stellate_cell, MESH:D055166, PMID:12808230, PMID:17239632, PMID:18222966, PMID:9302568] comment: Hepatic stellate cells are CD271-positive, desmin-positive, DDR-2-positive, GFAP-positive, synamin-positive, synaptophysin-positive, vimentin-positive, They are capable of producing angiotensin II, fibronectin, laminin, MMP-1, MMP-2, MMP-3, MMP-9, MMP-11, TGF-beta1, TIMP-1, TIMP-2, type I collagen, type III collagen, type IV collagen, and type VI collagen. +subset: cellxgene_subset subset: human_reference_atlas synonym: "fat-storing cell" RELATED [] synonym: "hepatic perisinusoidal cell" EXACT [] @@ -6925,6 +7084,7 @@ is_a: CL:0002165 ! phalangeal cell id: CL:0000636 name: Mueller cell def: "Astrocyte-like radial glial cell that extends vertically throughout the retina, with the nucleus are usually in the middle of the inner nuclear layer." [GOC:NV, PMID:21911394] +subset: cellxgene_subset subset: eye_upper_slim subset: human_reference_atlas synonym: "Muller cell" EXACT MISSPELLING [doi:10.21769/BioProtoc.4179] @@ -6998,6 +7158,7 @@ relationship: part_of UBERON:0002196 ! adenohypophysis id: CL:0000644 name: Bergmann glial cell def: "Type of radial astrocyte in the cerebellar cortex that have their cell bodies in the Purkinje cell layer and processes that extend into the molecular layer, terminating with bulbous endfeet at the pial surface. Bergmann glia express high densities of glutamate transporters that limit diffusion of the neurotransmitter glutamate during its release from synaptic terminals. Besides their role in early development of the cerebellum, Bergmann glia are also required for the pruning or addition of synapses." [GOC:tfm, http://www.neurolex.org/wiki/Category\:Bergmann_Glial_Cell] +subset: cellxgene_subset subset: human_reference_atlas synonym: "Bergmann astrocyte" EXACT [] synonym: "Bergmann glial cell of cerebellum" EXACT [] @@ -7019,6 +7180,7 @@ relationship: part_of UBERON:0002198 ! neurohypophysis id: CL:0000646 name: basal cell def: "Undifferentiated; mitotic stem cell for other epithelial cell types; rounded or elliptical with little cytoplasm and few organelles; contain cytokeratin intermediate filament." [GOC:tfm, ISBN:0517223651] +subset: cellxgene_subset subset: human_reference_atlas xref: BTO:0000939 xref: FMA:62516 @@ -7073,6 +7235,7 @@ id: CL:0000649 name: prickle cell alt_id: CL:0002186 def: "A cell with delicate radiating processes known as desmosomes that form intercellular bridges between other cells of this type. This cell type forms the stratum spinosum (prickle cell layer). A function of this cell is to generate keratin." [GOC:tfm, ISBN:0721662544, ISBN:0815332181] +subset: cellxgene_subset subset: human_reference_atlas synonym: "prickle cell of epidermis" EXACT [] xref: FMA:69059 @@ -7085,6 +7248,7 @@ id: CL:0000650 name: mesangial cell def: "A cell type that encapsulates the capillaries and venules in the kidney. This cell secretes mesangial matrix that provides the structural support for the capillaries." [GOC:tfm, http://www.copewithcytokines.de/cope.cgi?key=mesangial%20cells] comment: Do all of these cells really develop from some mesenchymal stem cell? +subset: cellxgene_subset synonym: "kidney mesangial cell" EXACT [] xref: BTO:0000853 xref: CALOHA:TS-0617 @@ -7097,6 +7261,7 @@ relationship: develops_from CL:0000134 ! mesenchymal stem cell id: CL:0000651 name: mucous neck cell def: "A mucus-secreting cell, with numerous apical secretory vesicles containing mucins; nucleus are basally displaced; numerous at the neck of mucus secreting glands" [GOC:tfm] +subset: cellxgene_subset synonym: "neck cell" BROAD [] is_a: CL:0000150 ! glandular epithelial cell is_a: CL:0000319 ! mucus secreting cell @@ -7117,6 +7282,7 @@ relationship: part_of UBERON:0001905 ! pineal body id: CL:0000653 name: podocyte def: "A specialized kidney epithelial cell, contained within a glomerulus, that contains \"feet\" that interdigitate with the \"feet\" of other podocytes." [GOC:tfm, https://doi.org/10.1101/2021.10.10.463829] +subset: cellxgene_subset subset: human_reference_atlas synonym: "epithelial cell of visceral layer of glomerular capsule" BROAD [FMA:70967] synonym: "glomerular podocyte" EXACT [FMA:70967] @@ -7224,27 +7390,28 @@ is_a: CL:0000468 ! neuroglioblast (sensu Nematoda and Protostomia) [Term] id: CL:0000663 name: obsolete valve cell -comment: https://github.com/obophenotype/cell-ontology/issues/726 +relationship: term_tracker_item https://github.com/obophenotype/cell-ontology/issues/726 is_obsolete: true replaced_by: CL:1000147 [Term] id: CL:0000664 name: obsolete closable valve cell -comment: https://github.com/obophenotype/cell-ontology/issues/726 +relationship: term_tracker_item https://github.com/obophenotype/cell-ontology/issues/726 is_obsolete: true replaced_by: CL:1000147 [Term] id: CL:0000665 name: obsolete permanently open valve cell -comment: https://github.com/obophenotype/cell-ontology/issues/726 +relationship: term_tracker_item https://github.com/obophenotype/cell-ontology/issues/726 is_obsolete: true replaced_by: CL:1000147 [Term] id: CL:0000666 name: fenestrated cell +subset: cellxgene_subset synonym: "window cell" EXACT [] is_a: CL:0000066 ! epithelial cell @@ -7252,6 +7419,7 @@ is_a: CL:0000066 ! epithelial cell id: CL:0000667 name: collagen secreting cell def: "An extracellular matrix secreting cell that secretes collagen." [GOC:tfm] +subset: cellxgene_subset is_a: CL:0000327 ! extracellular matrix secreting cell [Term] @@ -7269,6 +7437,7 @@ name: pericyte alt_id: CL:0000184 def: "An elongated, contractile cell found wrapped about precapillary arterioles outside the basement membrane. Pericytes are present in capillaries where proper adventitia and muscle layer are missing (thus distingushing this cell type from adventitial cells). They are relatively undifferentiated and may become fibroblasts, macrophages, or smooth muscle cells." [GOC:dsd, GOC:tfm, ISBN:0721662544, MESH:D020286, PMID:16807374, PMID:17986482, PMID:20024907] comment: Pericytes are CD10-positive, CD13-positive, CD31-negative, CD45-negative, CD106-positive, CD117-negative, CD140-positive, CD144-negative, CD146-positive, CD271-positive, CD325-positive, NG2-positive, RGS5-positive, SMA-positive, and desmin-positive. A subpopulation is CD248-positive. They are also capable of producing angiopoietin 1, CXCL12, TGF-beta, and VEGF-A. +subset: cellxgene_subset subset: human_reference_atlas synonym: "adventitial cell" RELATED [] synonym: "adventitial reticular cell" EXACT [] @@ -7288,6 +7457,7 @@ relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens id: CL:0000670 name: primordial germ cell def: "A primordial germ cell is a diploid germ cell precursors that transiently exist in the embryo before they enter into close association with the somatic cells of the gonad and become irreversibly committed as germ cells." [GOC:tfm, PMID:1381289] +subset: cellxgene_subset synonym: "gonocyte" EXACT [] synonym: "primitive germ cell" EXACT [] xref: FMA:70567 @@ -7349,6 +7519,7 @@ is_a: CL:0000378 ! supporting cell (sensu Nematoda and Protostomia) id: CL:0000677 name: gut absorptive cell def: "Cell of the intestinal epithelium with a brush border made up of many parallel packed microvilli; associated with absorption, particularly of macromolecules." [JB:jb] +subset: cellxgene_subset is_a: CL:0000000 ! cell relationship: part_of UBERON:0001277 ! intestinal epithelium @@ -7361,6 +7532,7 @@ is_a: CL:0000540 ! neuron id: CL:0000679 name: glutamatergic neuron def: "A neuron that is capable of some neurotansmission by glutamate secretion." [] +subset: cellxgene_subset subset: human_reference_atlas xref: FBbt:00100291 xref: WBbt:0006829 @@ -7375,17 +7547,19 @@ relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens id: CL:0000680 name: muscle precursor cell def: "A non-terminally differentiated cell that is capable of developing into a muscle cell." [GOC:add] +subset: cellxgene_subset is_a: CL:0000055 ! non-terminally differentiated cell intersection_of: CL:0011115 ! precursor cell -intersection_of: RO:0002203 CL:0000187 ! develops into muscle cell +intersection_of: develops_into CL:0000187 ! muscle cell relationship: develops_from CL:0000222 ! mesodermal cell -relationship: RO:0002203 CL:0000187 ! develops into muscle cell +relationship: develops_into CL:0000187 ! muscle cell [Term] id: CL:0000681 name: radial glial cell def: "A cell present in the developing CNS. Functions as both a precursor cell and as a scaffold to support neuronal migration." [GOC:dph] comment: Unlike that of mammals, the brain of adult teleost fish exhibits an intense and widespread neurogenic activity as a result of the persistence of\nradial glial cells acting as neural progenitors throughout life. +subset: cellxgene_subset synonym: "forebrain radial glial cell" NARROW [] is_a: CL:0000125 ! glial cell relationship: develops_from CL:0000710 ! neurecto-epithelial cell @@ -7395,6 +7569,7 @@ id: CL:0000682 name: M cell of gut def: "An absorptive cell of the gut epithelium that endocytoses microorganisms and intact macromolecules from the gut lumen and transports them to the subepithelial space where they are presented to antigen-presenting cells and lymphocytes." [GOC:jb, GOC:tfm] comment: Should double check and see if M cells are particular to a specific region. +subset: cellxgene_subset subset: human_reference_atlas synonym: "M cell" BROAD [] synonym: "M-cell" EXACT [] @@ -7513,6 +7688,7 @@ id: CL:0000695 name: Cajal-Retzius cell def: "A neuron of the human embryonic marginal zone which display, as a salient feature, radial ascending processes that contact the pial surface, and a horizontal axon plexus located in the deep marginal zone. One feature of these cells in mammals is that they express the Reelin gene." [PMID:10600995, PMID:9728912] comment: While previously called 'pioneer neurons' of the marginal zone, Cajal-Retzius cells are differentiated from pioneer neurons (which are Reln-negative) by their Reln-immunoreactivity. {xref="PMID:10600995"} +subset: cellxgene_subset synonym: "CR cells" EXACT [WikipediaVersioned:Cajal–Retzius_cell&oldid=1032081753] synonym: "Horizontal cells of Cajal" EXACT [WikipediaVersioned:Cajal–Retzius_cell&oldid=1032081753] is_a: CL:0000117 ! CNS neuron (sensu Vertebrata) @@ -7525,6 +7701,7 @@ relationship: RO:0002100 UBERON:0010403 ! has soma location brain marginal zone id: CL:0000696 name: PP cell def: "A cell that stores and secretes pancreatic polypeptide hormone." [GOC:tfm, JB:jb, PMID:15153415] +subset: cellxgene_subset synonym: "type F enteroendocrine cell" EXACT [] xref: FMA:62938 xref: FMA:83409 @@ -7554,6 +7731,7 @@ is_a: CL:0000165 ! neuroendocrine cell id: CL:0000700 name: dopaminergic neuron def: "A neuron that releases dopamine as a neurotransmitter." [GOC:dhill] +subset: cellxgene_subset synonym: "dopaminergic cell" EXACT [] xref: BTO:0004032 xref: FBbt:00005131 @@ -7590,6 +7768,7 @@ is_a: CL:0000630 ! supporting cell id: CL:0000704 name: endothelial tip cell def: "A specialized endothelial cell that senses extracellular signals and guides the directed growth of blood vessels." [PMID:15376331] +subset: cellxgene_subset is_a: CL:0000071 ! blood vessel endothelial cell [Term] @@ -7605,6 +7784,7 @@ id: CL:0000706 name: choroid plexus epithelial cell alt_id: CL:1000430 def: "Specialized ependymal cell that produces the cerebrospinal fluid from the blood and secretes it into the lumen of the brain and spinal chord." [GOC:add, GOC:tfm, JB:jb, PMID:9550134] +subset: cellxgene_subset subset: human_reference_atlas synonym: "choroid plexus cell" BROAD [DOI:10.1101/2022.10.12.511898] synonym: "epithelial cell of choroid plexus" EXACT [] @@ -7629,6 +7809,7 @@ is_a: CL:0000494 ! UV sensitive photoreceptor cell id: CL:0000708 name: leptomeningeal cell def: "Stromal cell that forms the internal covering of the vertebrate brain and produces ECM for this and the choroid plexus." [JB:jb] +subset: cellxgene_subset synonym: "leptomemingeal cell" RELATED [] is_a: CL:0000327 {is_inferred="true"} ! extracellular matrix secreting cell is_a: CL:0002319 ! neural cell @@ -7702,7 +7883,8 @@ is_a: CL:0000735 ! lymph gland hemocyte id: CL:0000717 name: obsolete fusimotor neuron def: "OBSOLETE. A subset of motor neurons that innervates intrafusal muscle fibers and has small diameter axons." [PMID:15582775] -comment: Term merged into CL:0008037. Refer to https://github.com/obophenotype/cell-ontology/issues/1364 +comment: Term merged into CL:0008037. +relationship: term_tracker_item https://github.com/obophenotype/cell-ontology/issues/1364 is_obsolete: true replaced_by: CL:0008037 @@ -7778,21 +7960,21 @@ is_a: CL:0000605 ! fungal asexual spore id: CL:0000727 name: obsolete primary pigment cell comment: Obsoleted as this level of precision is deemed unnecessary for CL. Consider using either the more general CL:0001658 or, if you need to refer to primary pigment cells specifically, a term from a taxon-specific ontology such as FBbt:00004231. -property_value: term_tracker_item "https://github.com/obophenotype/cell-ontology/issues/1930" xsd:string +relationship: term_tracker_item https://github.com/obophenotype/cell-ontology/issues/1930 is_obsolete: true [Term] id: CL:0000728 name: obsolete secondary pigment cell comment: Obsoleted as this level of precision is deemed unnecessary for CL. Consider using either the more general CL:0001658 or, if you need to refer to secondary pigment cells specifically, a term from a taxon-specific ontology such as FBbt:00004232. -property_value: term_tracker_item "https://github.com/obophenotype/cell-ontology/issues/1930" xsd:string +relationship: term_tracker_item https://github.com/obophenotype/cell-ontology/issues/1930 is_obsolete: true [Term] id: CL:0000729 name: obsolete tertiary pigment cell comment: Obsoleted as this level of precision is deemed unnecessary for CL. Consider using either the more general CL:0001658 or, if you need to refer to tertiary pigment cells specifically, a term from a taxon-specific ontology such as FBbt:00004233. -property_value: term_tracker_item "https://github.com/obophenotype/cell-ontology/issues/1930" xsd:string +relationship: term_tracker_item https://github.com/obophenotype/cell-ontology/issues/1930 is_obsolete: true [Term] @@ -7805,6 +7987,7 @@ is_a: CL:0000066 ! epithelial cell id: CL:0000731 name: urothelial cell def: "A cell of a layer of transitional epithelium in the wall of the proximal urethra, bladder, ureter or renal pelvis, external to the lamina propria." [doi:10.1038/s41385-022-00565-0, GOC:tfm, MA:ma] +subset: cellxgene_subset synonym: "urinary tract transitional epithelial cell" NARROW [] xref: FMA:84127 is_a: CL:0000244 ! transitional epithelial cell @@ -7864,6 +8047,7 @@ relationship: has_part GO:0030017 ! sarcomere id: CL:0000738 name: leukocyte def: "An achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue." [GOC:add, GOC:tfm, ISBN:978-0-323-05290-0] +subset: cellxgene_subset subset: human_reference_atlas synonym: "immune cell" RELATED [] synonym: "leucocyte" EXACT [] @@ -7890,6 +8074,7 @@ relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens id: CL:0000740 name: retinal ganglion cell def: "The set of neurons that receives neural inputs via bipolar, horizontal and amacrine cells. The axons of these cells make up the optic nerve." [GOC:dph] +subset: cellxgene_subset subset: eye_upper_slim subset: human_reference_atlas synonym: "gangliocyte" EXACT [] @@ -7935,6 +8120,7 @@ is_a: CL:0000138 ! chondrocyte id: CL:0000745 name: retina horizontal cell def: "A neuron that laterally connects other neurons in the inner nuclear layer of the retina." [ISBN:0195088433] +subset: cellxgene_subset subset: eye_upper_slim subset: human_reference_atlas synonym: "HC" RELATED OMO:0003000 [doi:10.1038/s41598-020-66092-9] @@ -7951,6 +8137,7 @@ name: cardiac muscle cell alt_id: FMA:83808 def: "Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. In mammals, the contractile fiber resembles those of skeletal muscle but are only one third as large in diameter, are richer in sarcoplasm, and contain centrally located instead of peripheral nuclei." [GOC:mtg_cardiacconduct_nov11, GOC:tfm, ISBN:0323052908, PMID:22426062, PMID:4711263] comment: This class encompasses the muscle cells responsible for heart* contraction in both vertebrates and arthropods. The ultrastucture of a wide range of arthropod heart cells has been examined including spiders, horseshoe crabs, crustaceans (see Sherman, 1973 and refs therein) and insects (see Lehmacher et al (2012) and refs therein). According to these refs, the cells participating in heart contraction in all cases are transversely striated. Insects hearts additionally contain ostial cells, also transversely striated muscle cells, but which do not participate in heart contraction. +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "cardiac muscle fiber" EXACT [GO:0048739] @@ -7986,6 +8173,7 @@ relationship: develops_from CL:0005005 ! cyanoblast id: CL:0000748 name: retinal bipolar neuron def: "A bipolar neuron found in the retina and having connections with photoreceptors cells and neurons in the inner plexiform layer." [PMID:14689473] +subset: cellxgene_subset subset: eye_upper_slim subset: human_reference_atlas synonym: "BC" RELATED OMO:0003000 [doi:10.1038/s41598-020-66092-9] @@ -8004,6 +8192,7 @@ relationship: RO:0002100 UBERON:0001791 ! has soma location inner nuclear layer id: CL:0000749 name: ON-bipolar cell def: "A bipolar neuron found in the retina and having connections with photoreceptors cells and neurons in the inner half of the inner plexiform layer. These cells depolarize in response to light stimulation of their corresponding photoreceptors." [PMID:14689473] +subset: cellxgene_subset subset: human_reference_atlas is_a: CL:0000748 ! retinal bipolar neuron relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens @@ -8012,6 +8201,7 @@ relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens id: CL:0000750 name: OFF-bipolar cell def: "A bipolar neuron found in the retina and having connections with photoreceptors cells and neurons in the outer half of the inner plexiform layer. These cells depolarize in response to light to dark transition." [PMID:14689473] +subset: cellxgene_subset subset: human_reference_atlas is_a: CL:0000748 ! retinal bipolar neuron relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens @@ -8020,6 +8210,7 @@ relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens id: CL:0000751 name: rod bipolar cell def: "A bipolar neuron found in the retina that is synapsed by rod photoreceptor cells but not by cone photoreceptor cells. These neurons depolarize in response to light." [GOC:tfm, PMID:14689473] +subset: cellxgene_subset subset: human_reference_atlas xref: FMA:67750 is_a: CL:0000255 ! eukaryotic cell @@ -8140,6 +8331,7 @@ relationship: develops_from CL:0000828 ! thromboblast id: CL:0000763 name: myeloid cell def: "A cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage." [GOC:add] +subset: cellxgene_subset xref: BTO:0001441 xref: CALOHA:TS-0647 xref: MESH:D022423 @@ -8154,6 +8346,7 @@ name: erythroid lineage cell alt_id: CL:0002156 def: "A immature or mature cell in the lineage leading to and including erythrocytes." [GOC:add, GOC:tfm] comment: Note that in FMA erythropoietic cells are types of nucleated erythrocytes and thus don't include erythrocytes. +subset: cellxgene_subset subset: human_reference_atlas synonym: "erythropoietic cell" EXACT [] xref: CALOHA:TS-0290 @@ -8167,6 +8360,7 @@ id: CL:0000765 name: erythroblast def: "A nucleated precursor of an erythrocyte that lacks hematopoietic lineage markers." [GOC:add, ISBN:0721601464, PMID:18174176] subset: blood_and_immune_upper_slim +subset: cellxgene_subset synonym: "normoblast" EXACT [] xref: BTO:0001571 xref: CALOHA:TS-0289 @@ -8209,6 +8403,7 @@ relationship: has_part GO:0005634 ! nucleus id: CL:0000766 name: myeloid leukocyte def: "A cell of the monocyte, granulocyte, or mast cell lineage." [GOC:add] +subset: cellxgene_subset is_a: CL:0000738 {is_inferred="true"} ! leukocyte is_a: CL:0000763 ! myeloid cell intersection_of: CL:0000738 ! leukocyte @@ -8220,6 +8415,7 @@ name: basophil def: "Any of the immature or mature forms of a granular leukocyte that in its mature form has an irregularly shaped, pale-staining nucleus that is partially constricted into two lobes, and with cytoplasm that contains coarse, bluish-black granules of variable size. Basophils contain vasoactive amines such as histamine and serotonin, which are released on appropriate stimulation. A basophil is CD123-positive, CD193-positive, CD203c-positive, and FceRIa-positive." [GOC:add, GOC:amm, GOC:dsd, GOC:tfm, ISBN:0721601464, MESH:D001491, PMCID:PMC2626675, PMID:11927641, PMID:19741522, PMID:21236338, PMID:9933081] comment: Matures in the bone marrow and account for <1% of leukocytes in the peripheral blood, spleen, and bone marrow. Basophils are described as being CD11a-positive, CD11b-positive, CD13-positive, CD15-positive, CD18-positive, CD21-positive, CD25-positive, CD29-positive, CD35-positive, CD40-positive, CD40L-positive, CD44-positive, CD45R-negative, CD46-positive, CD49a-positive, CD49b-positive, CD49d-positive, CD55-positive, CD59-positive, CD62L-positive, CD63-positive, CD69-positive, CD90-negative, CD116-positive, CD117-negative, CD124-positive, CD125-positive, CD131-positive, CD161-positive, CD184-positive, CD191-positive, CD192-positive, CD197-positive, CD200R3-positive, CD218-positive, CD282-positive, CD284-positive, CD289-positive, CD290-positive, CD294-positive, natural killer cell receptor 2B4-positive, smad1-positive, CD3-negative, CD4-negative, CD7-negative, CD8-negative, CD14-negative, CD15-negative, CD16-negative, CD19-negative, CD20-negative, CD34-negative, CD36-negative, CD45R-negative, CD56-negative, CD57-negative, CD235a-negative, and GR1-negative. Transcription factors- GATA1-positive, PU.1-positive. subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "basophilic leucocyte" EXACT [] synonym: "basophilic leukocyte" EXACT [] @@ -8299,6 +8495,7 @@ name: eosinophil def: "Any of the immature or mature forms of a granular leukocyte with a nucleus that usually has two lobes connected by one or more slender threads of chromatin, and cytoplasm containing coarse, round granules that are uniform in size and which can be stained by the dye eosin. Eosinophils are CD9-positive, CD191-positive, and CD193-positive." [GOC:add, GOC:amm, GOC:dsd, GOC:tfm, ISBN:0721601464, PMCID:PMC2626675, PMID:10914487, PMID:1662676] comment: Eosinophils are also CD14-negative, CD32-positive, CD44-positive, CD48-positive, CD69-positive, CD192-negative, MBP1-positive, MBP2-positive, TLR2-negative, TLR4-negative, and lineage-negative (B220, CD2, CD14, CD19, CD56, CD71, CD117, CD123, CD235a (glycophorin A), and TER119). The cytokines IL-3, IL-5, and GM-CSF are involved in their development and differentiation. Usually considered CD16-negative, CD16 is observed on eosinophilic metamyelocyte. subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "eosinocyte" EXACT [] synonym: "eosinophilic granulocyte" EXACT [] @@ -8382,6 +8579,7 @@ id: CL:0000775 name: neutrophil def: "Any of the immature or mature forms of a granular leukocyte that in its mature form has a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes." [GOC:add, GOC:amm, GOC:tfm, ISBN:0721601464] subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "neutrocyte" EXACT [] synonym: "neutrophil leucocyte" EXACT [] @@ -8411,6 +8609,7 @@ relationship: RO:0002104 PR:000001879 ! has plasma membrane part leukosialin id: CL:0000776 name: immature neutrophil def: "Any of the immature forms of a neutrophil in which neutrophilic specific granules are present but other phenotypic features of the mature form may be lacking." [GOC:add, ISBN:0721601464] +subset: cellxgene_subset synonym: "immatuer neutrophilic leukocyte" EXACT [] synonym: "immature neutrocyte" EXACT [] synonym: "immature neutrophil leucocyte" EXACT [] @@ -8484,6 +8683,7 @@ id: CL:0000782 name: myeloid dendritic cell def: "A dendritic cell of the myeloid lineage." [GOC:add, PMID:10449155, PMID:17332250, PMID:9521319] comment: These cells are CD1a-negative, CD1b-positive, CD11a-positive, CD11c-positive, CD13-positive, CD14-negative, CD20-negative, CD21-negative, CD33-positive, CD40-negative, CD50-positive, CD54-positive, CD58-positive, CD68-negative, CD80-negative, CD83-negative, CD85j-positive, CD86-positive, CD89-negative, CD95-positive, CD120a-negative, CD120b-positive, CD123-negative, CD178-negative, CD206-negative, CD207-negative, CD209-negative, and TNF-alpha-negative. Upon TLR stimulation, they are capable of producing high levels of TNF-alpha, IL-6, CXCL8 (IL-8). +subset: cellxgene_subset synonym: "CD11c+CD123- DC" EXACT [] synonym: "interdigitating cell" BROAD [] synonym: "mDC" EXACT [] @@ -8511,6 +8711,7 @@ id: CL:0000784 name: plasmacytoid dendritic cell def: "A dendritic cell type of distinct morphology, localization, and surface marker expression (CD123-positive) from other dendritic cell types and associated with early stage immune responses, particularly the release of physiologically abundant amounts of type I interferons in response to infection." [GOC:add, GOC:dsd, PMCID:PMC2118448, PMCID:PMC538703, PMID:15549123, PMID:17332250, PMID:17850486, PMID:20304825] subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "DC2" EXACT [] synonym: "interferon-producing cell" EXACT [] @@ -8533,6 +8734,7 @@ id: CL:0000785 name: mature B cell def: "A B cell that is mature, having left the bone marrow. Initially, these cells are IgM-positive and IgD-positive, and they can be activated by antigen." [GOC:add, GOC:dsd, ISBN:0781735149] comment: Mature B cells are also reportedly CD10-negative, CD19-positive, CD22-positive, CD34-negative, CD48-positive, CD79a-positive, CD84-positive, CD127-negative, CD352-positive, RAG-negative, TdT-negative, Vpre-B-negative, and pre-BCR-negative. Transcription factors expressed: Pax5-positive. +subset: cellxgene_subset synonym: "mature B lymphocyte" EXACT [] synonym: "mature B-cell" EXACT [] synonym: "mature B-lymphocyte" EXACT [] @@ -8555,6 +8757,7 @@ name: plasma cell def: "A terminally differentiated, post-mitotic, antibody secreting cell of the B cell lineage with the phenotype CD138-positive, surface immunonoglobulin-negative, and MHC Class II-negative. Plasma cells are oval or round with extensive rough endoplasmic reticulum, a well-developed Golgi apparatus, and a round nucleus having a characteristic cartwheel heterochromatin pattern and are devoted to producing large amounts of immunoglobulin." [GO_REF:0000031, GOC:add, GOC:dsd, http://en.wikipedia.org/wiki/Plasma_cell, ISBN:0721601464, ISBN:0781735149, PMID:19447676, PMID:20081059, PMID:20839338, PMID:20951740] comment: Plasma cells develop in the spleen and migrate to the bone marrow. Plasma cells are also reportedly CD5-negative, CD10-negative, CD19-positive, CD20-negative, CD21-negative, CD22-negative, CD23-negative, CD24-negative, CD25-negative, CD27-positive, CD34-negative, CD38-positive, CD40-positive, CD43-positive, CD45-positive, CD48-positive, CD53-low, CD80-negative, CD81-positive, CD86-positive, CD95-positive, CD196-negative, CD229-positive, CD270-positive, CD352-positive, CD361-positive, and IgD-negative. Transcription factors: BLIMP1-positive, IRF4-positive, PAX5-negative, SpiB-negative, Ets1-negative, and XBP1-positive. subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "effector B cell" RELATED [] synonym: "effector B-cell" RELATED [] @@ -8587,6 +8790,7 @@ id: CL:0000787 name: memory B cell def: "A memory B cell is a mature B cell that is long-lived, readily activated upon re-encounter of its antigenic determinant, and has been selected for expression of higher affinity immunoglobulin. This cell type has the phenotype CD19-positive, CD20-positive, MHC Class II-positive, and CD138-negative." [GO_REF:0000031, GOC:add, GOC:dsd, GOC:rhs, http://en.wikipedia.org/wiki/Memory_B_cell, ISBN:0781735149, PMID:20081059, PMID:20839338] comment: Memory B-cells are also reportedly CD5-negative, CD10-negative, CD21-positive, CD22-positive, CD23-negative, CD24-positive, CD25-positive, CD27-positive, CD34-negative, CD38-negative, CD40-positive, CD43-negative, CD44-positive, CD45-positive, CD53-positive, CD80-negative, CD81-negative, CD86-positive, and CD196/CCR6-positive. +subset: cellxgene_subset subset: human_reference_atlas synonym: "memory B lymphocyte" EXACT [] synonym: "memory B-cell" EXACT [] @@ -8608,6 +8812,7 @@ id: CL:0000788 name: naive B cell def: "A naive B cell is a mature B cell that has the phenotype surface IgD-positive, surface IgM-positive, CD20-positive, CD27-negative and that has not yet been activated by antigen in the periphery." [GO_REF:0000031, GOC:add, GOC:dsd, GOC:rhs, ISBN:0781765196, PMID:19447676, PMID:20081059, PMID:20839338, PMID:20933013, PMID:22343568] comment: This cell type is compatible with the HIPC Lyoplate markers for 'naive B cell'. Per DSD: Naive B cells are also reportedly CD10-negative, CD19-positive, CD20-positive, CD21-positive, CD22-positive, CD25-negative, CD27-negative, CD34-negative, CD40-positive, CD43-negative, CD45-positive, CD48-positive, CD53-positive, CD80-negative, CD81-positive, CD84-positive, CD86-negative, CD95-negative, CD138-negative, CD150-positive, CD184/CXCR4-positive, CD185/CXCR5-positive, CD196/CCR6-positive, CD200-positive, CD229-positive, CD243-positive, CD289-positive, CD290-positive, CD352-positive, MHCII/HLA-DR-positive, cadherin 9-positive, and sIgH-positive, Transcription factors: Pax5-positive, ETS1-positive, FOXO1A-positive, KLF4-positive, KLF9-positive, MiTF-positive, OBF1-positive, PLZF-positive, and SpiB-positive. +subset: cellxgene_subset subset: human_reference_atlas synonym: "naive B lymphocyte" EXACT [] synonym: "naive B-cell" EXACT [] @@ -8631,6 +8836,7 @@ id: CL:0000789 name: alpha-beta T cell def: "A T cell that expresses an alpha-beta T cell receptor complex." [GOC:add, GOC:tfm, ISBN:0781735149] subset: blood_and_immune_upper_slim +subset: cellxgene_subset synonym: "alpha-beta T lymphocyte" EXACT [] synonym: "alpha-beta T-cell" EXACT [] synonym: "alpha-beta T-lymphocyte" EXACT [] @@ -8644,6 +8850,7 @@ relationship: RO:0002104 GO:0042105 ! has plasma membrane part alpha-beta T cell id: CL:0000790 name: immature alpha-beta T cell def: "An alpha-beta T cell that has an immature phenotype and has not completed T cell selection." [GOC:add, GOC:tfm, ISBN:0781735149] +subset: cellxgene_subset synonym: "immature alpha-beta T lymphocyte" EXACT [] synonym: "immature alpha-beta T-cell" EXACT [] synonym: "immature alpha-beta T-lymphocyte" EXACT [] @@ -8656,6 +8863,7 @@ intersection_of: CL:4030044 GO:0045058 ! has_not_completed T cell selection id: CL:0000791 name: mature alpha-beta T cell def: "A alpha-beta T cell that has a mature phenotype." [GOC:add, GOC:tfm, ISBN:0781735149] +subset: cellxgene_subset synonym: "mature alpha-beta T lymphocyte" EXACT [] synonym: "mature alpha-beta T-cell" EXACT [] synonym: "mature alpha-beta T-lymphocyte" EXACT [] @@ -8670,6 +8878,7 @@ id: CL:0000792 name: CD4-positive, CD25-positive, alpha-beta regulatory T cell def: "A CD4-positive, CD25-positive, alpha-beta T cell that regulates overall immune responses as well as the responses of other T cell subsets through direct cell-cell contact and cytokine release." [GOC:add, GOC:tfm, ISBN:0781735149, PMID:19464985, PMID:22343568] comment: This cell type is compatible with the HIPC Lyoplate markers for 'Treg'. The inclusion of CD127lo in the logical definition is compatible with both human and mouse T cells of this subtype. +subset: cellxgene_subset synonym: "CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte" EXACT [] synonym: "CD4-positive, CD25-positive, alpha-beta regulatory T-cell" EXACT [] synonym: "CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte" EXACT [] @@ -8710,6 +8919,7 @@ id: CL:0000794 name: CD8-positive, alpha-beta cytotoxic T cell def: "A CD8-positive, alpha-beta T cell that is capable of killing target cells in an antigen specific manner with the phenotype perforin-positive and granzyme B-positive." [GO_REF:0000031, GOC:add, GOC:pam, GOC:tfm, ISBN:0781735149] comment: Note that while T cells of this subset are loosely referred to 'cytotoxic T cells,' as many other T cell types, including CD4-positive, alpha-beta T cells and gamma-delta T cells exhibit cytotoxicity in vitro and in vivo. +subset: cellxgene_subset subset: human_reference_atlas synonym: "CD8-positive, alpha-beta cytotoxic T lymphocyte" EXACT [] synonym: "CD8-positive, alpha-beta cytotoxic T-cell" EXACT [] @@ -8764,6 +8974,7 @@ intersection_of: capable_of GO:0050777 ! negative regulation of immune response id: CL:0000796 name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell def: "A alpha-beta intraepithelial T cell found in the columnar epithelium of the gastrointestinal tract. Intraepithelial T cells often have distinct developmental pathways and activation requirements." [GOC:add, ISBN:0781735149] +subset: cellxgene_subset subset: human_reference_atlas synonym: "CD8-positive, alpha-beta intraepithelial T lymphocyte" EXACT [] synonym: "CD8-positive, alpha-beta intraepithelial T-cell" EXACT [] @@ -8797,6 +9008,7 @@ name: gamma-delta T cell def: "A T cell that expresses a gamma-delta T cell receptor complex." [GOC:add, GOC:tfm, ISBN:0781735149] comment: Note that gamma-delta T cells have both thymic and extrathymic differentiation pathways. subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "gamma-delta T lymphocyte" EXACT [] synonym: "gamma-delta T-cell" EXACT [] @@ -8829,6 +9041,7 @@ relationship: develops_from CL:0000807 ! DN3 thymocyte id: CL:0000800 name: mature gamma-delta T cell def: "A gamma-delta T cell that has a mature phenotype. These cells can be found in tissues and circulation where they express unique TCR repertoire depending on their location." [GOC:add, GOC:tfm, ISBN:0781735149] +subset: cellxgene_subset synonym: "mature gamma-delta T lymphocyte" EXACT [] synonym: "mature gamma-delta T-cell" EXACT [] synonym: "mature gamma-delta T-lymphocyte" EXACT [] @@ -8857,6 +9070,7 @@ intersection_of: located_in UBERON:0001277 ! intestinal epithelium id: CL:0000802 name: CD8-alpha alpha positive, gamma-delta intraepithelial T cell def: "A gamma-delta intraepithelial T cell that has the phenotype CD8-alpha alpha-positive." [GOC:add, GOC:tfm, ISBN:0781735149] +subset: cellxgene_subset subset: human_reference_atlas synonym: "CD8-positive, gamma-delta intraepithelial T lymphocyte" EXACT [] synonym: "CD8-positive, gamma-delta intraepithelial T-cell" EXACT [] @@ -8940,6 +9154,7 @@ id: CL:0000807 name: DN3 thymocyte def: "A thymocyte that has the phenotype CD4-negative, CD8-negative, CD44-negative, and CD25-positive and expressing the T cell receptor beta-chain in complex with the pre-T cell receptor alpha chain." [GO_REF:0000031, GOC:add, GOC:tfm, ISBN:0781735149] comment: There is growing evidence that molecular markers characterizing double negative thymocytes are different across species, especially in mouse versus human thymus. If in doubt, please consider using CL:0002489 'double negative thymocyte'. +subset: cellxgene_subset synonym: "DN3 alpha-beta immature T lymphocyte" EXACT [] synonym: "DN3 alpha-beta immature T-cell" EXACT [] synonym: "DN3 alpha-beta immature T-lymphocyte" EXACT [] @@ -8967,6 +9182,7 @@ id: CL:0000808 name: DN4 thymocyte def: "A thymocyte that has the phenotype CD4-negative, CD8-negative, CD44-negative, CD25-negative, and pre-TCR-positive." [GO_REF:0000031, GOC:add, GOC:tfm, ISBN:0781735149] comment: Note that this type of thymocyte has passed the beta-selection checkpoint and is rapidly proliferating and beginning to rearrange the T cell receptor alpha chain. There is growing evidence that molecular markers characterizing double negative thymocytes are different across species, especially in mouse versus human thymus. If in doubt, please consider using CL:0002489 'double negative thymocyte'. +subset: cellxgene_subset synonym: "DN4 alpha-beta immature T lymphocyte" EXACT [] synonym: "DN4 alpha-beta immature T-lymphocyte" EXACT [] synonym: "DN4 cell" EXACT [] @@ -8992,6 +9208,7 @@ id: CL:0000809 name: double-positive, alpha-beta thymocyte def: "A thymocyte expressing the alpha-beta T cell receptor complex as well as both the CD4 and CD8 coreceptors." [GO_REF:0000031, GOC:add, GOC:tfm, ISBN:0781735149] comment: Thymocytes of this stage are undergoing positive and negative selection. +subset: cellxgene_subset subset: human_reference_atlas synonym: "double-positive, alpha-beta immature T lymphocyte" EXACT [] synonym: "DP cell" EXACT [] @@ -9012,6 +9229,7 @@ relationship: RO:0002104 PR:000025402 ! has plasma membrane part T cell receptor id: CL:0000810 name: CD4-positive, alpha-beta thymocyte def: "An immature alpha-beta T cell that is located in the thymus and is CD4-positive and CD8-negative." [GO_REF:0000031, GOC:add, GOC:tfm, ISBN:0781735149] +subset: cellxgene_subset synonym: "CD4-positive, alpha-beta immature T lymphocyte" EXACT [] synonym: "CD4-positive, alpha-beta immature T-cell" EXACT [] synonym: "CD4-positive, alpha-beta immature T-lymphocyte" EXACT [] @@ -9030,6 +9248,7 @@ relationship: RO:0002104 PR:000001004 ! has plasma membrane part CD4 molecule id: CL:0000811 name: CD8-positive, alpha-beta thymocyte def: "An immature alpha-beta T cell that is located in the thymus and is CD8-positive and CD4-negative." [GO_REF:0000031, GOC:add, GOC:tfm, ISBN:0781735149] +subset: cellxgene_subset synonym: "CD8-positive, alpha-beta immature T cell" RELATED [] synonym: "CD8-positive, alpha-beta immature T lymphocyte" EXACT [] synonym: "CD8-positive, alpha-beta immature T-cell" EXACT [] @@ -9049,6 +9268,7 @@ relationship: RO:0002104 PR:000025402 ! has plasma membrane part T cell receptor id: CL:0000813 name: memory T cell def: "A long-lived, antigen-experienced T cell that has acquired a memory phenotype including distinct surface markers and the ability to differentiate into an effector T cell upon antigen reexposure." [GO_REF:0000031, GOC:add, GOC:pam, GOC:tfm, ISBN:0781735149] +subset: cellxgene_subset synonym: "memory T lymphocyte" EXACT [] synonym: "memory T-cell" EXACT [] synonym: "memory T-lymphocyte" EXACT [] @@ -9066,6 +9286,7 @@ relationship: output_of GO:0043379 ! memory T cell differentiation id: CL:0000814 name: mature NK T cell def: "A mature alpha-beta T cell of a distinct lineage that bears natural killer markers and a T cell receptor specific for a limited set of ligands. NK T cells have activation and regulatory roles particularly early in an immune response." [GOC:add, ISBN:0781735149] +subset: cellxgene_subset subset: human_reference_atlas synonym: "mature natural killer T cell" EXACT [] synonym: "mature natural killer T lymphocyte" EXACT [] @@ -9093,6 +9314,7 @@ id: CL:0000815 name: regulatory T cell def: "A T cell which regulates overall immune responses as well as the responses of other T cell subsets through direct cell-cell contact and cytokine release." [GO_REF:0000031, GOC:add] comment: This cell type may express FoxP3 and CD25 and secretes IL-10 and TGF-beta. +subset: cellxgene_subset subset: human_reference_atlas synonym: "regulatory T lymphocyte" EXACT [] synonym: "regulatory T-cell" EXACT [] @@ -9117,6 +9339,7 @@ name: immature B cell def: "An immature B cell is a B cell that has the phenotype surface IgM-positive and surface IgD-negative, and have not undergone class immunoglobulin class switching or peripheral encounter with antigen and activation." [GO_REF:0000031, GOC:add, GOC:dsd, GOC:rhs, GOC:tfm, ISBN:0781735149, PMID:20081059, PMID:20839338] comment: Immature B cells are also reportedly CD5-positive, CD10-positive, CD19-positive, CD20-positive, CD21-positive, CD22-positive, CD24-positive, CD25-negative, CD27-negative, CD34-negative, CD38-positive, CD40-positive, CD43-negative, CD45-positive, CD48-positive, CD53-positive, CD79a-positive, CD80-negative, CD81-positive, CD86-negative, CD95-negative, CD127-negative, CD138-negative, CD185-positive, CD196-positive, MHCII/HLA-DR-positive, RAG-positive, TdT-negative, Vpre-B-negative, and preBCR-negative. Transcription factors expressed: Pax5-positive. subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "immature B lymphocyte" EXACT [] synonym: "immature B-cell" EXACT [] @@ -9139,6 +9362,7 @@ relationship: RO:0002104 PR:000001289 ! has plasma membrane part membrane-spanni id: CL:0000817 name: precursor B cell def: "A precursor B cell is a B cell with the phenotype CD10-positive." [GO_REF:0000031, GOC:rhs, GOC:tfm] +subset: cellxgene_subset subset: human_reference_atlas synonym: "pre-B cell" RELATED [] xref: BTO:0001133 @@ -9157,6 +9381,7 @@ id: CL:0000818 name: transitional stage B cell def: "An immature B cell of an intermediate stage between the pre-B cell stage and the mature naive stage with the phenotype surface IgM-positive and CD19-positive, and are subject to the process of B cell selection. A transitional B cell migrates from the bone marrow into the peripheral circulation, and then to the spleen." [GO_REF:0000031, GOC:add, ISBN:0781735149, PMID:12810111, PMID:22343568] comment: This cell type is compatible with the HIPC Lyoplate markers for 'transitional B cell'. +subset: cellxgene_subset subset: human_reference_atlas synonym: "T1 B cell" NARROW [] synonym: "T2 B cell" NARROW [] @@ -9185,6 +9410,7 @@ id: CL:0000819 name: B-1 B cell def: "A B cell of distinct lineage and surface marker expression. B-1 B cells are thought to be the primary source of natural IgM immunoglobulin, that is, IgM produced in large quantities without prior antigenic stimulation and generally reactive against various microorganisms, as well as the source of T-independent IgA immunoglobulin in the mucosal areas. These cells are CD43-positive." [GO_REF:0000031, GOC:add, GOC:dsd, http://en.wikipedia.org/wiki/B-1_cell, PMID:11861604, PMID:20933013, PMID:21220451] comment: There are small numbers of B-1 cells found in the lymph nodes and spleen, while larger numbers can be found in the peritoneal and pleural cavities. B-1 B cells are reportedly CD11b-positive, CD20-positive, CD21-positive, CD27-positive, CD44-positive, CD45RB-positive, CD48-positive, CD70-negative, CD150-positive, CD244-negative, CD352-positive, sIgM-positive, and sIgD-low. +subset: cellxgene_subset synonym: "B-1 B lymphocyte" EXACT [] synonym: "B-1 B-cell" EXACT [] synonym: "B-1 B-lymphocyte" EXACT [] @@ -9211,6 +9437,7 @@ relationship: RO:0015015 GO:0071753 ! has high plasma membrane amount IgM immuno id: CL:0000820 name: B-1a B cell def: "A B-1 B cell that has the phenotype CD5-positive." [GOC:add, PMID:11861604] +subset: cellxgene_subset synonym: "B-1a B lymphocyte" EXACT [] synonym: "B-1a B-cell" EXACT [] synonym: "B-1a B-lymphocyte" EXACT [] @@ -9231,6 +9458,7 @@ relationship: RO:0002104 PR:000001839 ! has plasma membrane part T-cell surface id: CL:0000821 name: B-1b B cell def: "A B-1 B cell that has the phenotype CD5-negative, but having other phenotypic attributes of a B-1 B cell." [GOC:add, PMID:11861604] +subset: cellxgene_subset synonym: "B-1b B lymphocyte" EXACT [] synonym: "B-1b B-cell" EXACT [] synonym: "B-1b B-lymphocyte" EXACT [] @@ -9249,6 +9477,7 @@ id: CL:0000822 name: B-2 B cell def: "A conventional B cell subject to antigenic stimulation and dependent on T cell help and with a distinct surface marker expression pattern from B-1 B cells. These cells are CD43-negative." [GOC:add, GOC:dsd, GOC:tfm, ISBN:0781735149, PMID:11861604, PMID:20933013] comment: B-2 B cells are reportedly CD48-positive, CD244-negative, and CD352-positive. +subset: cellxgene_subset synonym: "B-0 B cell" RELATED [] synonym: "B-2 B lymphocyte" EXACT [] synonym: "B-2 B-cell" EXACT [] @@ -9270,6 +9499,7 @@ id: CL:0000823 name: immature natural killer cell def: "A natural killer cell that is developmentally immature and expresses natural killer cell receptors (NKR)." [GO_REF:0000031, GOC:add, ISBN:0781735149, PMID:12457618] comment: In mouse the NKR are Ly49 molecules and in human these cells express KIR molecules. +subset: cellxgene_subset synonym: "immature NK cell" EXACT [] synonym: "p-NK" RELATED [PMID:12457618] is_a: CL:0000623 ! natural killer cell @@ -9324,6 +9554,7 @@ id: CL:0000826 name: pro-B cell def: "A progenitor cell of the B cell lineage, with some lineage specific activity such as early stages of recombination of B cell receptor genes, but not yet fully committed to the B cell lineage until the expression of PAX5 occurs." [GOC:add, GOC:dsd, ISBN:0781735149, PMID:12633665, PMID:16551251, PMID:18432934] comment: Human pro-B cells are reportedly CD10-positive, CD22-positive, CD34-positive, CD38-positive, CD45-low, CD48-positive, CD79a-positive, CD127-positive, CD184-positive, RAG-positive, TdT-positive, Vpre-B-positive, pre-BCR-negative, IgD-negative, and IgM-negative. Transcription factors expressed: Pax5-positive, EBF-positive, E2A-negative, Ikaros-negative, and PU.1-negative. +subset: cellxgene_subset subset: human_reference_atlas synonym: "pre-B cell (Philadelphia nomenclature)" RELATED [PMID:11244048] synonym: "pre-pro B cell" BROAD [PMID:17582343] @@ -9351,6 +9582,7 @@ relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens id: CL:0000827 name: pro-T cell def: "A lymphoid progenitor cell of the T cell lineage, with some lineage specific marker expression, but not yet fully committed to the T cell lineage." [GOC:add, ISBN:0781735149] +subset: cellxgene_subset synonym: "DN1 cell" NARROW [] synonym: "DN1 thymocyte" NARROW [] synonym: "pro-T lymphocyte" EXACT [] @@ -9485,6 +9717,7 @@ relationship: develops_from CL:0000832 ! eosinophilic myeloblast id: CL:0000834 name: neutrophil progenitor cell def: "A progenitor cell of the neutrophil lineage." [GOC:add, GOC:tfm, ISBN:0721601464] +subset: cellxgene_subset synonym: "neutrophil stem cell" RELATED [] is_a: CL:0000763 ! myeloid cell is_a: CL:0002191 {is_inferred="true"} ! granulocytopoietic cell @@ -9503,20 +9736,21 @@ is_a: CL:0000763 ! myeloid cell is_a: CL:0002191 {is_inferred="true"} ! granulocytopoietic cell is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0002191 ! granulocytopoietic cell +intersection_of: bearer_of PATO:0040072 ! high nuclear/cytoplasmic ratio intersection_of: CL:4030045 GO:0042582 ! lacks_part azurophil granule intersection_of: has_part CL:0017503 ! basophilic cytoplasm -intersection_of: has_part CL:0017505 ! increased nucleus size intersection_of: has_part GO:0000791 ! euchromatin +relationship: bearer_of PATO:0040072 ! high nuclear/cytoplasmic ratio relationship: CL:4030045 GO:0042582 ! lacks_part azurophil granule relationship: develops_from CL:0000557 ! granulocyte monocyte progenitor cell relationship: has_part CL:0017503 ! basophilic cytoplasm -relationship: has_part CL:0017505 ! increased nucleus size relationship: has_part GO:0000791 ! euchromatin [Term] id: CL:0000836 name: promyelocyte def: "A precursor in the granulocytic series, being a cell intermediate in development between a myeloblast and myelocyte, that has distinct nucleoli, a nuclear-to-cytoplasmic ratio of 5:1 to 3:1, and containing a few primary cytoplasmic granules. Markers for this cell are fucosyltransferase FUT4-positive, CD33-positive, integrin alpha-M-negative, low affinity immunoglobulin gamma Fc region receptor III-negative, and CD24-negative." [GOC:add, GOC:amm, GOC:tfm, http://www.cap.org, ISBN:0721601464] +subset: cellxgene_subset subset: human_reference_atlas xref: CALOHA:TS-0825 xref: FMA:83530 @@ -9524,21 +9758,21 @@ is_a: CL:0000763 ! myeloid cell is_a: CL:0002191 ! granulocytopoietic cell is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000839 ! myeloid lineage restricted progenitor cell +intersection_of: bearer_of PATO:0040072 ! high nuclear/cytoplasmic ratio intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M intersection_of: CL:4030046 PR:000001483 ! lacks_plasma_membrane_part low affinity immunoglobulin gamma Fc region receptor III intersection_of: CL:4030046 PR:000001932 ! lacks_plasma_membrane_part signal transducer CD24 intersection_of: has_part CL:0017503 ! basophilic cytoplasm -intersection_of: has_part CL:0017505 ! increased nucleus size intersection_of: has_part GO:0005730 ! nucleolus intersection_of: has_part GO:0042582 ! azurophil granule intersection_of: RO:0002104 PR:000001456 ! has plasma membrane part alpha-(1,3)-fucosyltransferase 4 intersection_of: RO:0002104 PR:000001892 ! has plasma membrane part CD33 molecule +relationship: bearer_of PATO:0040072 ! high nuclear/cytoplasmic ratio relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M relationship: CL:4030046 PR:000001483 ! lacks_plasma_membrane_part low affinity immunoglobulin gamma Fc region receptor III relationship: CL:4030046 PR:000001932 ! lacks_plasma_membrane_part signal transducer CD24 relationship: develops_from CL:0000835 ! myeloblast relationship: has_part CL:0017503 ! basophilic cytoplasm -relationship: has_part CL:0017505 ! increased nucleus size relationship: has_part GO:0005730 ! nucleolus relationship: has_part GO:0042582 ! azurophil granule relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens @@ -9551,6 +9785,7 @@ name: hematopoietic multipotent progenitor cell def: "A hematopoietic multipotent progenitor cell is multipotent, but not capable of long-term self-renewal. These cells are characterized as lacking lineage cell surface markers and being CD34-positive in both mice and humans." [GOC:add, GOC:tfm, PMID:19022770] comment: Markers differ between mouse and human. subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "hemopoietic progenitor cell" EXACT [] synonym: "MPP" EXACT [] @@ -9598,6 +9833,7 @@ id: CL:0000838 name: lymphoid lineage restricted progenitor cell def: "A progenitor cell restricted to the lymphoid lineage." [GOC:add, GOC:tfm] comment: Note that this is a class of cell types, not an identified single cell type. +subset: cellxgene_subset synonym: "lymphoid progenitor cell" BROAD [] xref: BTO:0004731 xref: CALOHA:TS-2025 @@ -9614,6 +9850,7 @@ id: CL:0000839 name: myeloid lineage restricted progenitor cell def: "A progenitor cell restricted to the myeloid lineage." [GOC:add, GOC:tfm, PMID:19022770] comment: Note that this is a class of cell types, not an identified single cell type. +subset: cellxgene_subset subset: human_reference_atlas synonym: "myeloid progenitor cell" BROAD [] xref: BTO:0004730 @@ -9648,6 +9885,7 @@ relationship: RO:0015016 PR:000001438 ! has low plasma membrane amount CD80 mole id: CL:0000841 name: mature conventional dendritic cell def: "A mature cell of the conventional dendritic cell lineage, characterized by a high capacity for antigen presentation and typically found in a lymph node." [GOC:add, GOC:tfm, PMID:9521319] +subset: cellxgene_subset synonym: "mature dendritic cell" BROAD [GOC:add] synonym: "mature myeloid dendritic cell" NARROW [] xref: FMA:83038 @@ -9669,6 +9907,7 @@ id: CL:0000842 name: mononuclear cell def: "A leukocyte with a single non-segmented nucleus in the mature form." [GOC:add] subset: blood_and_immune_upper_slim +subset: cellxgene_subset synonym: "mononuclear leukocyte" EXACT [] synonym: "peripheral blood mononuclear cell" NARROW [] xref: BTO:0000878 @@ -9684,6 +9923,7 @@ id: CL:0000843 name: follicular B cell def: "A resting mature B cell that has the phenotype IgM-positive, IgD-positive, CD23-positive and CD21-positive, and found in the B cell follicles of the white pulp of the spleen or the corticol areas of the peripheral lymph nodes. This cell type is also described as being CD19-positive, B220-positive, AA4-negative, CD43-negative, and CD5-negative." [GOC:add, GOC:dsd, http://en.wikipedia.org/wiki/Follicular_B_Cells, ISBN:0781735149, PMCID:PMC2193793, PMID:20933013] comment: Follicular B cells are also reportedly CD48-positive, CD84-positive, CD229-positive, and CD352-positive. +subset: cellxgene_subset synonym: "Fo B cell" EXACT [] synonym: "Fo B-cell" EXACT [] synonym: "follicular B lymphocyte" EXACT [] @@ -9711,6 +9951,7 @@ id: CL:0000844 name: germinal center B cell def: "A rapidly cycling mature B cell that has distinct phenotypic characteristics and is involved in T-dependent immune responses and located typically in the germinal centers of lymph nodes. This cell type expresses Ly77 after activation." [GOC:add, GOC:dsd, GOC:tfm, ISBN:0781735149, PMID:19447676, PMID:20933013] comment: Germinal center B cells are also reportedly CD10-positive, CD19-positive, CD20-positive, CD38-positive, CD44-low, CD45-positive, CD48-positive, CD95-positive, CD352-positive, and HLA-DR-positive. Transcription factors: BCL6-positive, Ets1-positive, IRF8-positive, MTA3-positive, OBF1-positive, PAX5-positive, SpiB-positive, and STAT3-positive. +subset: cellxgene_subset subset: human_reference_atlas synonym: "GC B cell" EXACT [] synonym: "GC B lymphocyte" EXACT [] @@ -9876,8 +10117,8 @@ name: slow muscle myoblast def: "A skeletal muscle myoblast that differentiates into slow muscle fibers." [SANBI:mhl] is_a: CL:0000515 ! skeletal muscle myoblast intersection_of: CL:0000056 ! myoblast -intersection_of: RO:0002203 CL:0000189 ! develops into slow muscle cell -relationship: RO:0002203 CL:0000189 ! develops into slow muscle cell +intersection_of: develops_into CL:0000189 ! slow muscle cell +relationship: develops_into CL:0000189 ! slow muscle cell [Term] id: CL:0000858 @@ -9885,14 +10126,15 @@ name: fast muscle myoblast def: "A skeletal muscle myoblast that differentiates into fast muscle fibers." [SANBI:mhl] is_a: CL:0000515 ! skeletal muscle myoblast intersection_of: CL:0000056 ! myoblast -intersection_of: RO:0002203 CL:0000190 ! develops into fast muscle cell -relationship: RO:0002203 CL:0000190 ! develops into fast muscle cell +intersection_of: develops_into CL:0000190 ! fast muscle cell +relationship: develops_into CL:0000190 ! fast muscle cell [Term] id: CL:0000860 name: classical monocyte def: "A monocyte that responds rapidly to microbial stimuli by secreting cytokines and antimicrobial factors and which is characterized by high expression of CCR2 in both rodents and humans, negative for the lineage markers CD3, CD19, and CD20, and of larger size than non-classical monocytes." [GO_REF:0000031, GOC:add, PMID:16322748, PMID:18303997, PMID:20628149, PMID:20870168] comment: Markers: CCR2+CXCCR1 (human, mouse, rat). +subset: cellxgene_subset subset: human_reference_atlas synonym: "inflammatory monocyte" EXACT [] is_a: CL:0000576 {is_inferred="true"} ! monocyte @@ -9918,6 +10160,7 @@ id: CL:0000861 name: elicited macrophage def: "A macrophage which develops from an inflammatory monocyte and is recruited into the tissues in response to injury and infection as part of an inflammatory response. Markers include CD11b-positive, CD68-positive, and F4/80-positive." [GO_REF:0000031, GOC:add, GOC:ana, GOC:tfm, PMID:15771589] comment: Markers: CD11b+, CD68+; Mouse: F4/80+; role or process: immune, inflammation (inflammatory response). +subset: cellxgene_subset synonym: "free macrophage" EXACT [] synonym: "wandering histiocyte" EXACT [] xref: FMA:84643 @@ -9950,6 +10193,7 @@ id: CL:0000863 name: inflammatory macrophage def: "An elicited macrophage that is recruited into the tissues in response to injury and infection as part of an inflammatory response, expresses high levels of pro-inflammatory cytokines, ROS and NO, and shows potent microbicidal activity." [GO_REF:0000031, GOC:ana, PMID:19132917] comment: Markers: Express: TNFa, IL1b, IL6, iNOS, NADPH-oxidase; produce: reactive oxygen species, nitric oxide; role or process: immune, inflammation (inflammatory response). +subset: cellxgene_subset synonym: "classically activated macrophage" EXACT [] synonym: "M1 macrophage" RELATED [PMID:28923980] is_a: CL:0000861 {is_inferred="true"} ! elicited macrophage @@ -9971,6 +10215,7 @@ relationship: capable_of GO:0051767 ! nitric-oxide synthase biosynthetic process id: CL:0000864 name: tissue-resident macrophage def: "A macrophage constitutively resident in a particular tissue under non-inflammatory conditions, and capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells." [GO_REF:0000031, GOC:ana, PMID:19770654] +subset: cellxgene_subset subset: human_reference_atlas synonym: "fixed macrophage" EXACT [] synonym: "resting histiocyte" EXACT [] @@ -10142,6 +10387,7 @@ id: CL:0000875 name: non-classical monocyte def: "A type of monocyte characterized by low expression of CCR2, low responsiveness to monocyte chemoattractant CCL2/MCP1, low phagocytic activity, and decrease size relative to classical monocytes, but increased co-stimulatory activity. May also play a role in tissue repair." [GO_REF:0000031, GOC:add, PMID:16322748, PMID:18303997, PMID:20628149, PMID:20870168] comment: Markers: CCR2-CX3CCR1+ (human, mouse, rat); human: CD16+, CCR5+, CD32/FcgRII-high, MHCII+, CD86+; mouse: CD62L-Ly6C-. +subset: cellxgene_subset subset: human_reference_atlas synonym: "patrolling monocyte" EXACT [] synonym: "resident monocyte" EXACT [] @@ -10201,6 +10447,7 @@ relationship: RO:0002104 PR:000010329 ! has plasma membrane part tyrosine-protei id: CL:0000878 name: central nervous system macrophage def: "A tissue-resident macrophage found in the central nervous system." [GO_REF:0000031, PMID:16322748] +subset: cellxgene_subset synonym: "CNS macrophage" EXACT [] is_a: CL:0000864 {is_inferred="true"} ! tissue-resident macrophage is_a: CL:0002319 ! neural cell @@ -10354,6 +10601,7 @@ id: CL:0000890 name: alternatively activated macrophage def: "An elicited macrophage characterized by low production of pro-inflammatory and Th1 polarizing cytokines and high expression of arginase-1, and associated with tissue remodelling." [GO_REF:0000031, GOC:ana, GOC:tfm, PMID:20510870] comment: Role or process: tissue remodeling. +subset: cellxgene_subset synonym: "M2 macrophage" RELATED [PMID:28923980] is_a: CL:0000861 {is_inferred="true"} ! elicited macrophage intersection_of: CL:0000861 ! elicited macrophage @@ -10382,6 +10630,7 @@ relationship: develops_from CL:0000192 ! smooth muscle cell id: CL:0000893 name: thymocyte def: "An immature T cell located in the thymus." [GO_REF:0000031, GOC:add, GOC:tfm, PMID:12415312] +subset: cellxgene_subset synonym: "immature T cell" BROAD [] synonym: "immature T lymphocyte" BROAD [] synonym: "immature T-cell" BROAD [] @@ -10402,6 +10651,7 @@ relationship: part_of UBERON:0002370 ! thymus id: CL:0000894 name: DN1 thymic pro-T cell def: "A pro-T cell that has the phenotype CD4-negative, CD8-negative, CD44-positive, and CD25-negative." [GO_REF:0000031, GOC:add, GOC:tfm] +subset: cellxgene_subset synonym: "DN1 thymic pro-T lymphocyte" EXACT [] synonym: "DN1 thymic pro-T-cell" EXACT [] synonym: "DN1 thymic pro-T-lymphocyte" EXACT [] @@ -10429,6 +10679,7 @@ id: CL:0000895 name: naive thymus-derived CD4-positive, alpha-beta T cell def: "An antigen inexperienced CD4-positive, alpha-beta T cell with the phenotype CCR7-positive, CD127-positive and CD62L-positive. This cell type develops in the thymus. This cell type is also described as being CD25-negative, CD62L-high, and CD44-low." [GO_REF:0000031, GOC:add, GOC:tfm, http://www.immgen.org/index_content.html, PMID:19100699, PMID:22343568] comment: These cells have not been exposed to antigen following thymic T-cell selection; found in blood and secondary lymphoid organs. This cell type is compatible with the HIPC Lyoplate markers for 'naive CD4+ T cell', but includes additional markers known to be expressed on naive CD4+ T cells. +subset: cellxgene_subset subset: human_reference_atlas synonym: "naive CD4+ T cell" BROAD [PMID:22343568] synonym: "naive thymus-derived CD4-positive, alpha-beta T lymphocyte" EXACT [] @@ -10453,6 +10704,7 @@ relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens id: CL:0000896 name: activated CD4-positive, alpha-beta T cell def: "A recently activated CD4-positive, alpha-beta T cell with the phenotype CD69-positive, CD62L-negative, CD127-negative, and CD25-positive." [GO_REF:0000031, GOC:add, GOC:pam] +subset: cellxgene_subset synonym: "activated CD4-positive, alpha-beta T lymphocyte" EXACT [] synonym: "activated CD4-positive, alpha-beta T-cell" EXACT [] synonym: "activated CD4-positive, alpha-beta T-lymphocyte" EXACT [] @@ -10472,6 +10724,7 @@ relationship: RO:0002104 PR:000001380 ! has plasma membrane part interleukin-2 r id: CL:0000897 name: CD4-positive, alpha-beta memory T cell def: "A CD4-positive, alpha-beta T cell that has differentiated into a memory T cell." [GOC:add, http://www.immgen.org/index_content.html, ISBN:0781735149] +subset: cellxgene_subset subset: human_reference_atlas synonym: "CD4-positive, alpha-beta memory T lymphocyte" EXACT [] synonym: "CD4-positive, alpha-beta memory T-cell" EXACT [] @@ -10490,6 +10743,7 @@ relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens id: CL:0000898 name: naive T cell def: "Mature T cell not yet exposed to antigen with the phenotype CCR7-positive, CD45RA-positive, and CD127-positive. This cell type is also described as being CD25-negative, CD62L-high and CD44-low." [GO_REF:0000031, GOC:add, GOC:pam, GOC:tfm, PMID:19100699] +subset: cellxgene_subset synonym: "naive T lymphocyte" EXACT [] synonym: "naive T-cell" EXACT [] synonym: "naive T-lymphocyte" EXACT [] @@ -10512,6 +10766,7 @@ id: CL:0000899 name: T-helper 17 cell def: "CD4-positive, alpha-beta T cell with the phenotype RORgamma-t-positive, CXCR3-negative, CCR6-positive, and capable of producing IL-17." [GO_REF:0000031, GOC:add, GOC:pam, PMID:20303875, PMID:20969597, PMID:22343568] comment: This cell type is compatible with the HIPC Lyoplate markers for 'Th17 CD4+ T cell', but its logical definition includes additional known characteristics of T-helper 17 T cells. +subset: cellxgene_subset subset: human_reference_atlas synonym: "helper T cell type 17" EXACT [] synonym: "IL-17-producing CD4+ T helper" EXACT [] @@ -10541,6 +10796,7 @@ id: CL:0000900 name: naive thymus-derived CD8-positive, alpha-beta T cell def: "A CD8-positive, alpha-beta T cell that has not experienced activation via antigen contact and has the phenotype CD45RA-positive, CCR7-positive and CD127-positive. This cell type is also described as being CD25-negative, CD62L-high and CD44-low." [GO_REF:0000031, GOC:add, GOC:tfm, http://www.immgen.org/index_content.html, ISBN:0781735149, PMID:22343568] comment: This cell traffics in secondary lymphoid organs and blood. This cell type is compatible with the HIPC Lyoplate markers for 'naive CD8+ T cell', but includes additional markers known to be expressed on naive CD8+ T cells. +subset: cellxgene_subset subset: human_reference_atlas synonym: "naive CD8+ T cell" BROAD [PMID:22343568] synonym: "naive thymus-dervied CD8-positive, alpha-beta T lymphocyte" EXACT [] @@ -10602,6 +10858,7 @@ relationship: RO:0002104 PR:000001852 ! has plasma membrane part cytotoxic T-lym id: CL:0000903 name: natural T-regulatory cell def: "CD4-positive alpha-beta T cell with the phenotype FoxP3-positive, CD25-positive, CD62L-positive, and CTLA-4 positive with regulatory function." [GO_REF:0000031, GOC:add, GOC:pam, GOC:tfm, PMID:19464985] +subset: cellxgene_subset synonym: "natural regulatory T cell" EXACT [] synonym: "natural regulatory T lymphocyte" EXACT [] synonym: "natural regulatory T-cell" EXACT [] @@ -10624,6 +10881,7 @@ id: CL:0000904 name: central memory CD4-positive, alpha-beta T cell def: "CD4-positive, alpha-beta memory T cell with the phenotype CCR7-positive, CD127-positive, CD45RA-negative, CD45RO-positive, and CD25-negative." [GO_REF:0000031, GOC:add, GOC:pam, PMID:22343568] comment: This cell type is compatible with the HIPC Lyoplate markers for 'central memory CD4+ T cell', but includes additional markers known to be expressed on central memory CD4+ T cells. +subset: cellxgene_subset synonym: "central CD4-positive, alpha-beta memory T cell" EXACT [] synonym: "central CD4-positive, alpha-beta memory T lymphocyte" EXACT [] synonym: "central CD4-positive, alpha-beta memory T-cell" EXACT [] @@ -10645,6 +10903,7 @@ id: CL:0000905 name: effector memory CD4-positive, alpha-beta T cell def: "CD4-positive, alpha-beta memory T cell with the phenotype CCR7-negative, CD127-positive, CD45RA-negative, CD45RO-positive, and CD25-negative." [GO_REF:0000031, GOC:add, GOC:pam, GOC:tfm, PMID:22343568] comment: This cell type is compatible with the HIPC Lyoplate markers for 'effector memory CD4+ T cell', but includes additional markers known to be expressed on effector memory CD4+ T cells. +subset: cellxgene_subset subset: human_reference_atlas synonym: "effector CD4-positive, alpha-beta memory T cell" EXACT [] synonym: "effector CD4-positive, alpha-beta memory T lymphocyte" EXACT [] @@ -10667,6 +10926,7 @@ relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens id: CL:0000906 name: activated CD8-positive, alpha-beta T cell def: "A CD8-positive, alpha-beta T cell with the phenotype CD69-positive, CD62L-negative, CD127-negative, CD25-positive, and CCR7-negative." [GO_REF:0000031, GOC:add, GOC:pam, GOC:tfm] +subset: cellxgene_subset synonym: "activated CD8-positive, alpha-beta T lymphocyte" EXACT [] synonym: "activated CD8-positive, alpha-beta T-cell" EXACT [] synonym: "activated CD8-positive, alpha-beta T-lymphocyte" EXACT [] @@ -10689,6 +10949,7 @@ id: CL:0000907 name: central memory CD8-positive, alpha-beta T cell def: "CD8-positive, alpha-beta memory T cell with the phenotype CCR7-positive, CD127-positive, CD45RA-negative, CD45RO-positive, and CD25-negative." [GO_REF:0000031, GOC:add, GOC:pam, GOC:tfm, PMID:20146720, PMID:22343568] comment: This cell type is compatible with the HIPC Lyoplate markers for 'central memory CD8+ T cell', but includes additional markers known to be expressed on central memory CD8+ T cells. +subset: cellxgene_subset synonym: "central CD8-positive, alpha-beta memory T cell" EXACT [] synonym: "central CD8-positive, alpha-beta memory T lymphocyte" EXACT [] synonym: "central CD8-positive, alpha-beta memory T-cell" EXACT [] @@ -10709,6 +10970,7 @@ relationship: RO:0002104 PR:000001203 ! has plasma membrane part C-C chemokine r id: CL:0000908 name: CD8-positive, alpha-beta cytokine secreting effector T cell def: "A CD8-positive, alpha-beta T cell with the phenotype CD69-positive, CD62L-negative, CD127-negative, and CD25-positive, that secretes cytokines." [GO_REF:0000031, GOC:add, GOC:pam, GOC:tfm, PMID:20146720] +subset: cellxgene_subset synonym: "CD8-positive, alpha-beta cytokine secreting effector T lymphocyte" EXACT [] synonym: "CD8-positive, alpha-beta cytokine secreting effector T-cell" EXACT [] synonym: "CD8-positive, alpha-beta cytokine secreting effector T-lymphocyte" EXACT [] @@ -10732,6 +10994,7 @@ relationship: RO:0002104 PR:000001380 ! has plasma membrane part interleukin-2 r id: CL:0000909 name: CD8-positive, alpha-beta memory T cell def: "A CD8-positive, alpha-beta T cell that has differentiated into a memory T cell." [GOC:add, PMID:20146720] +subset: cellxgene_subset subset: human_reference_atlas synonym: "CD8-positive, alpha-beta memory T lymphocyte" EXACT [] synonym: "CD8-positive, alpha-beta memory T-cell" EXACT [] @@ -10750,6 +11013,7 @@ relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens id: CL:0000910 name: cytotoxic T cell def: "A mature T cell that differentiated and acquired cytotoxic function with the phenotype perforin-positive and granzyme-B positive." [GO_REF:0000031, GOC:add, GOC:pam, GOC:tfm, PMID:18395547] +subset: cellxgene_subset subset: human_reference_atlas synonym: "cytotoxic T lymphocyte" EXACT [] synonym: "cytotoxic T-cell" EXACT [] @@ -10782,6 +11046,7 @@ relationship: output_of GO:0030217 ! T cell differentiation id: CL:0000912 name: helper T cell def: "A effector T cell that provides help in the form of secreted cytokines to other immune cells." [GO_REF:0000031, GOC:add, GOC:pam, GOC:tfm, PMID:18395547] +subset: cellxgene_subset synonym: "helper T lymphocyte" EXACT [] synonym: "helper T-cell" EXACT [] synonym: "helper T-lymphocyte" EXACT [] @@ -10798,6 +11063,7 @@ id: CL:0000913 name: effector memory CD8-positive, alpha-beta T cell def: "CD8-positive, alpha-beta memory T cell with the phenotype CCR7-negative, CD127-positive, CD45RA-negative, CD45RO-positive, and CD25-negative." [GO_REF:0000031, GOC:add, GOC:pam, PMID:20146720, PMID:22343568] comment: This cell type is compatible with the HIPC Lyoplate markers for 'effector memory CD8+ T cell', but includes additional markers known to be expressed on effector memory CD8+ T cells. +subset: cellxgene_subset subset: human_reference_atlas synonym: "effector CD8-positive, alpha-beta memory T cell" EXACT [] synonym: "effector CD8-positive, alpha-beta memory T lymphocyte" EXACT [] @@ -10820,6 +11086,7 @@ relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens id: CL:0000914 name: immature NK T cell def: "An immature alpha-beta T-cell that express Egr2. These cells give rise to T cells expressing NK markers." [GO_REF:0000031, GOC:add, GOC:pam, GOC:tfm, PMID:17589542, PMID:19169262] +subset: cellxgene_subset subset: human_reference_atlas synonym: "immature NK T lymphocyte" EXACT [] synonym: "immature NK T-cell" EXACT [] @@ -10836,6 +11103,7 @@ relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens id: CL:0000915 name: CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell def: "An alpha-beta intraepithelial T cell with the phenotype CD8-alpha-alpha-positive located in the columnar epithelium of the gastrointestinal tract. These cells have a memory phenotype of CD2-negative and CD5-negative." [GO_REF:0000031, GOC:add, GOC:pam, PMID:11685222] +subset: cellxgene_subset subset: human_reference_atlas synonym: "CD8-alpha-alpha-positive, alpha-beta intraepithelial T lymphocyte" EXACT [] synonym: "CD8-alpha-alpha-positive, alpha-beta intraepithelial T-cell" EXACT [] @@ -10973,6 +11241,7 @@ id: CL:0000921 name: type I NK T cell def: "An alpha-beta T cell expressing NK cell markers that is CD1d restricted and expresses specific V-alpha chains. NK T cells of this type recognize the glycolipid alpha-galactosylceramide in the context of CD1d." [GO_REF:0000031, GOC:add, GOC:pam, GOC:tfm, PMID:15039760] comment: In mouse the canonical TCR is V-alpha-14, and in humans it is V-alpha 24. +subset: cellxgene_subset subset: human_reference_atlas synonym: "classical NK T cell" EXACT [] synonym: "invariant NK T cell" RELATED [] @@ -10990,6 +11259,7 @@ relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens id: CL:0000922 name: type II NK T cell def: "An alpha-beta T cell expressing NK call markers that is CD1d restricted and expresses a diverse TCR repertoire. Type II NKT cells do not become activated by alpha-galactosylceramide when presented by CD1d." [GO_REF:0000031, GOC:add, GOC:pam, GOC:tfm, PMID:15039760] +subset: cellxgene_subset synonym: "type II NK T lymphocyte" EXACT [] synonym: "type II NK T-cell" EXACT [] synonym: "type II NK T-lymphocyte" EXACT [] @@ -11146,6 +11416,7 @@ relationship: develops_from CL:0000928 ! activated CD4-negative, CD8-negative ty id: CL:0000931 name: activated type II NK T cell def: "A type II NK T cell that has been recently activated, secretes interferon-gamma and interleukin-4, and has the phenotype CD69-positive and downregulated NK markers." [GO_REF:0000031, GOC:add, GOC:pam, GOC:tfm, PMID:17964217] +subset: cellxgene_subset synonym: "activated type II NK T lymphocyte" EXACT [] synonym: "activated type II NK T-cell" EXACT [] synonym: "activated type II NK T-lymphocyte" EXACT [] @@ -11195,6 +11466,7 @@ relationship: RO:0002104 PR:000001343 ! has plasma membrane part CD69 molecule id: CL:0000934 name: CD4-positive, alpha-beta cytotoxic T cell def: "A CD4-positive, alpha-beta T cell that has cytotoxic function." [GO_REF:0000031, GOC:add, GOC:pam, GOC:tfm, PMID:18440213] +subset: cellxgene_subset subset: human_reference_atlas synonym: "CD4-positive, alpha-beta cytotoxic T lymphocyte" EXACT [] synonym: "CD4-positive, alpha-beta cytotoxic T-cell" EXACT [] @@ -11229,6 +11501,7 @@ id: CL:0000936 name: early lymphoid progenitor def: "A lymphoid progenitor cell that is found in bone marrow, gives rise to B cells, T cells, natural killer cells and dendritic cells, and has the phenotype Lin-negative, Kit-positive, Sca-1-positive, FLT3-positive, CD34-positive, CD150 negative, and GlyA-negative." [GO_REF:0000031, GOC:add, GOC:dsd, GOC:pam, GOC:tfm, PMID:19022770] comment: Markers are associated with mouse cells. ELP transcription factors include E2A-positive, Ikaros-positive, EBF-negative, Pax5-negative, PU.1-negative. +subset: cellxgene_subset subset: human_reference_atlas synonym: "ELP" RELATED OMO:0003000 [] synonym: "GMLP" RELATED OMO:0003000 [PMID:18371378] @@ -11256,6 +11529,7 @@ id: CL:0000937 name: pre-natural killer cell def: "Cell committed to natural killer cell lineage that has the phenotype CD122-positive, CD34-positive, and CD117-positive. This cell type lacks expression of natural killer receptor proteins." [GO_REF:0000031, GOC:add, GOC:dsd, GOC:pam, GOC:tfm, PMID:16551251, PMID:17100874] comment: These cells are also reportedly CD7-low, CD10-negative, CD45RA-positive, alpha-4-beta-7 integrin-high. +subset: cellxgene_subset synonym: "pre-NK cell" EXACT [] is_a: CL:0000623 ! natural killer cell intersection_of: CL:0000623 ! natural killer cell @@ -11271,6 +11545,7 @@ id: CL:0000938 name: CD16-negative, CD56-bright natural killer cell, human def: "NK cell that has the phenotype CD56-bright, CD16-negative, and CD84-positive with the function to secrete interferon-gamma but is not cytotoxic." [GO_REF:0000031, GOC:add, GOC:pam, GOC:tfm, PMID:19796267, PMID:22343568] comment: This cell type is compatible with the HIPC Lyoplate markers for 'CD16-CD56bright NK cell'. Markers are associated with human cell types. +subset: cellxgene_subset subset: human_reference_atlas synonym: "CD16-CD56bright NK cell" EXACT [PMID:22343568] synonym: "CD16-negative, CD56-bright NK cell" EXACT [] @@ -11296,6 +11571,7 @@ id: CL:0000939 name: CD16-positive, CD56-dim natural killer cell, human def: "A mature natural killer cell that has the phenotype CD56-low, CD16-positive and which is capable of cytotoxicity and cytokine production." [GO_REF:0000031, GOC:add, GOC:pam, PMID:19796267, PMID:22343568] comment: This cell type is compatible with the HIPC Lyoplate markers for 'CD16+CD56+ NK cell'. Markers are associated with human cell types. +subset: cellxgene_subset synonym: "CD16+CD56+ NK cell" EXACT [PMID:22343568] synonym: "CD16-positive, CD56-dim NK cell" EXACT [] synonym: "CD16-positive, CD56-low natural killer cell" EXACT [] @@ -11322,6 +11598,7 @@ relationship: RO:0015016 PR:000001024 ! has low plasma membrane amount neural ce id: CL:0000940 name: mucosal invariant T cell def: "An alpha-beta T cell that is found in the lamina propria of mucosal tissues and is restricted by the MR-1 molecule." [GO_REF:0000031, GOC:add, GOC:pam, GOC:tfm, PMID:19416870] +subset: cellxgene_subset subset: human_reference_atlas synonym: "mucosal invariant T lymphocyte" EXACT [] synonym: "mucosal invariant T-cell" EXACT [] @@ -11513,6 +11790,7 @@ id: CL:0000954 name: small pre-B-II cell def: "A small pre-B-II cell is a pre-B-II cell that is Rag1-positive, Rag2-positive, pre-BCR-negative, and BCR-negative, is not proliferating, and carries a DNA rearrangement of one or more immunoglobulin light chain genes." [GO_REF:0000031, GOC:dsd, GOC:rhs, GOC:tfm, PMID:16551251, PMID:18432934, PMID:9785673] comment: Small pre-B-II cells are also reportedly CD10-positive, CD19-positive, CD34-negative, CD79a-positive, CD127-negative, TdT-negative, Vpre-B-negative, sIgM-negative, and sIgD-negative. Transcription factors: PU.1-positive, Ikaros-positive, E2A-positive, and PAX5-positive. +subset: cellxgene_subset synonym: "small pre-BII cell" EXACT [] is_a: CL:0000955 {is_inferred="true"} ! pre-B-II cell intersection_of: CL:0000955 ! pre-B-II cell @@ -11551,6 +11829,7 @@ id: CL:0000956 name: pre-B-I cell def: "A pre-B-I cell is a precursor B cell that expresses CD34 and surrogate immunoglobulin light chain (VpreB , Lambda 5 (mouse)/14.1 (human)) on the cell surface, and TdT, Rag1,and Rag2 intracellularly. Cell type carries a D-JH DNA rearrangement, and lacks expression of immunglobulin heavy chain protein." [GO_REF:0000031, GOC:dsd, GOC:rhs, GOC:tfm, PMID:16551251, PMID:18432934, PMID:20839338, PMID:9785673] comment: Human pre-B-I cells are reportedly CD10-positive, CD19-positive, CD22-positive, CD38-positive, CD45-low, CD79a-positive, CD127-negative, pre-BCR-negative, IgM-negative, IgD-negative, and Tdt-positive. Transcription factors expressed: Pax5-positive. +subset: cellxgene_subset synonym: "pre-BI cell" EXACT [] synonym: "pro-B cell (Philadelphia nomenclature)" RELATED [PMID:11244048] is_a: CL:0000817 {is_inferred="true"} ! precursor B cell @@ -11575,6 +11854,7 @@ id: CL:0000957 name: large pre-B-II cell def: "A large pre-B-II cell is a pre-B-II cell that is proliferating and is Rag1-negative and Rag2-negative." [GO_REF:0000031, GOC:dsd, GOC:rhs, PMID:16551251, PMID:18432934, PMID:9785673] comment: Large pre-B-II cells are also reportedly CD10-positive, CD19-positive, CD34-negative, CD79a-positive, CD127-negative, TdT-negative, Vpre-B-positive, pre-BCR-positive, sIgM-negative, and sIgD-negative. Transcription factors: PU.1-positive, Ikaros-positive, E2A-positive, and PAX5-positive. +subset: cellxgene_subset synonym: "large pre-B cell" BROAD [PMID:11244048] synonym: "large pre-BII cell" EXACT [] is_a: CL:0000955 {is_inferred="true"} ! pre-B-II cell @@ -11832,6 +12112,7 @@ id: CL:0000970 name: unswitched memory B cell def: "An unswitched memory B cell is a memory B cell that has the phenotype IgM-positive, IgD-positive, CD27-positive, CD138-negative, IgG-negative, IgE-negative, and IgA-negative." [GO_REF:0000031, GOC:add, GOC:dsd, GOC:rhs, ISBN:0781765196, PMID:20933013, PMID:22343568] comment: This cell type is compatible with the HIPC Lyoplate markers for 'IgD+ memory B cell'. Per DSD: Unswitched memory B cells are also reportedly CD48-positive, CD84-positive, CD229-positive, and CD352-positive. +subset: cellxgene_subset subset: human_reference_atlas synonym: "IgD+ memory B cell" BROAD [PMID:22343568] synonym: "non-class-switched memory B cell" EXACT [HP:0032126] @@ -11879,6 +12160,7 @@ id: CL:0000972 name: class switched memory B cell def: "A class switched memory B cell is a memory B cell that has undergone Ig class switching and therefore is IgM-negative on the cell surface. These cells are CD27-positive and have either IgG, IgE, or IgA on the cell surface." [GO_REF:0000031, GOC:add, GOC:dsd, GOC:rhs, ISBN:0781765196, PMID:20933013, PMID:9295047] comment: Per DSD: Class switched memory B cells are also reportedly CD48-positive, CD229-positive, and CD352-positive. +subset: cellxgene_subset subset: human_reference_atlas synonym: "class switched memory B lymphocyte" EXACT [] synonym: "class switched memory B-cell" EXACT [] @@ -11970,6 +12252,7 @@ relationship: produces GO:0071754 ! IgM immunoglobulin complex, circulating id: CL:0000979 name: IgG memory B cell def: "An IgG memory B cell is a class switched memory B cell that is class switched and expresses IgG on the cell surface." [GO_REF:0000031, GOC:rhs, ISBN:0781765196] +subset: cellxgene_subset synonym: "IgG memory B lymphocyte" EXACT [] synonym: "IgG memory B-cell" EXACT [] synonym: "IgG memory B-lymphocyte" EXACT [] @@ -11987,6 +12270,7 @@ id: CL:0000980 name: plasmablast def: "An activated mature (naive or memory) B cell that is secreting immunoglobulin, typified by being CD27-positive, CD38-positive, CD138-negative." [GO_REF:0000031, GOC:dsd, GOC:msz, GOC:tfm, PMCID:PMC2673126] comment: This cell type is compatible with the HIPC Lyoplate markers for 'plasmablast'. Plasmablasts are also reportedly CD48-positive, CD63-positive, CD229-positive, CD270-positive, CD319-positive, CD352-positive, CD361-positive, and IgD-negative. +subset: cellxgene_subset subset: human_reference_atlas synonym: "CD20-negative B cell" BROAD [] synonym: "CD27-positive, CD38-positive, CD20-negative B cell" EXACT [] @@ -12027,6 +12311,7 @@ relationship: CL:4030046 PR:000001963 ! lacks_plasma_membrane_part CD27 molecule id: CL:0000982 name: IgG plasmablast def: "A plasmablast that secretes IgG." [GO_REF:0000031, GOC:msz] +subset: cellxgene_subset is_a: CL:0000980 {is_inferred="true"} ! plasmablast intersection_of: CL:0000980 ! plasmablast intersection_of: produces GO:0071736 ! IgG immunoglobulin complex, circulating @@ -12045,6 +12330,7 @@ relationship: produces GO:0071754 ! IgM immunoglobulin complex, circulating id: CL:0000984 name: IgA plasmablast def: "A plasmablast that secretes IgA." [GO_REF:0000031, GOC:msz] +subset: cellxgene_subset is_a: CL:0000980 {is_inferred="true"} ! plasmablast intersection_of: CL:0000980 ! plasmablast intersection_of: produces GO:0071746 ! IgA immunoglobulin complex, circulating @@ -12054,6 +12340,7 @@ relationship: produces GO:0071746 ! IgA immunoglobulin complex, circulating id: CL:0000985 name: IgG plasma cell def: "A fully differentiated plasma cell that secretes IgG." [GO_REF:0000031, GOC:msz, ISBN:781735149] +subset: cellxgene_subset is_a: CL:0000974 {is_inferred="true"} ! long lived plasma cell intersection_of: CL:0000974 ! long lived plasma cell intersection_of: produces GO:0071736 ! IgG immunoglobulin complex, circulating @@ -12063,6 +12350,7 @@ relationship: produces GO:0071736 ! IgG immunoglobulin complex, circulating id: CL:0000986 name: IgM plasma cell def: "A fully differentiated plasma cell that secretes IgM." [GO_REF:0000031, GOC:msz, ISBN:781735149] +subset: cellxgene_subset is_a: CL:0000974 {is_inferred="true"} ! long lived plasma cell intersection_of: CL:0000974 ! long lived plasma cell intersection_of: produces GO:0071754 ! IgM immunoglobulin complex, circulating @@ -12072,6 +12360,7 @@ relationship: produces GO:0071754 ! IgM immunoglobulin complex, circulating id: CL:0000987 name: IgA plasma cell def: "A fully differentiated plasma cell that secretes IgA." [GO_REF:0000031, GOC:msz, ISBN:781735149] +subset: cellxgene_subset is_a: CL:0000974 {is_inferred="true"} ! long lived plasma cell intersection_of: CL:0000974 ! long lived plasma cell intersection_of: produces GO:0071746 ! IgA immunoglobulin complex, circulating @@ -12081,6 +12370,7 @@ relationship: produces GO:0071746 ! IgA immunoglobulin complex, circulating id: CL:0000988 name: hematopoietic cell def: "A cell of a hematopoietic lineage." [GO_REF:0000031, GOC:add] +subset: cellxgene_subset synonym: "haematopoietic cell" EXACT [] synonym: "haemopoietic cell" EXACT [] synonym: "hemopoietic cell" EXACT [] @@ -12112,6 +12402,7 @@ name: conventional dendritic cell def: "Conventional dendritic cell is a dendritic cell that is CD11c-high." [GO_REF:0000031, GOC:amm, PMID:17850486] comment: Originally described in the dendritic cell ontology (DC_CL:0000003)(PMID:19243617) These cells are also CD20-negative, MHCII-positive. subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "cDC" EXACT [] synonym: "DC1" EXACT [] @@ -12641,6 +12932,7 @@ id: CL:0001024 name: CD34-positive, CD38-negative hematopoietic stem cell def: "CD133-positive hematopoietic stem cell is a hematopoietic stem cell that is CD34-positive, CD90-positive, and CD133-positive." [GO_REF:0000031, GOC:add, GOC:amm, GOC:tfm, PMID:10430905, PMID:11750107, PMID:16551251, PMID:20024907, PMID:9389721] comment: Cell markers are associated with human hematopoietic stem cells. Originally described in the dendritic cell ontology (DC_CL:0000035)(PMID:19243617). +subset: cellxgene_subset synonym: "CD133-positive hematopoietic stem cell" EXACT [PMID:16140871] xref: CALOHA:TS-0448 is_a: CL:0000037 {is_inferred="true"} ! hematopoietic stem cell @@ -12755,6 +13047,7 @@ id: CL:0001029 name: common dendritic progenitor def: "Common dendritic precursor is a hematopoietic progenitor cell that is CD117-low, CD135-positive, CD115-positive and lacks plasma membrane parts for hematopoietic lineage markers." [GO_REF:0000031, GOC:amm, GOC:tfm, PMID:16551251, PMID:17922016, PMID:19286519] comment: Surface markers are for mouse cells. Originally described in the dendritic cell ontology (DC_CL:0000041) CDP are reportedly CD2-negative, CD3-negative, CD4-negative, CD5-negative, CD8a-negative, CD11c-positive, CD14-negative, CD19-negative, CD20-negative, CD56-negative, B220-negative, Ly6g-negative, MHCII-positive, and Ter119-negative. (PMID:19243617). +subset: cellxgene_subset synonym: "CDP" EXACT [PMID:21219184] synonym: "common dendritic precursor" EXACT [] synonym: "pro-DCs" EXACT [PMID:21219184] @@ -12807,6 +13100,7 @@ id: CL:0001031 name: cerebellar granule cell def: "An excitatory granule cell with a soma located in the granular layer of cerebellar cortex. A mature cerebellar granule cell has short dendrites with a characteristic claw-like appearance and a long axon that ascends to the molecular layer where it bifurcates (except in non-teleost fish, where it does not bifurcate) and extends mediolaterally to form parallel fibers." [doi:10.12688/f1000research.15021.1, doi:10.3389/fncir.2020.611841, GOC:mah] comment: It has been noted in at least some mammalian species that granule cells are the most numerous cell type in the cerebellum and in the brain, with at least 99% of all cerebellar neurons being granule cells. {xref="doi:10.3389/fncir.2020.611841"} +subset: cellxgene_subset synonym: "granule cell of the cerebellum" EXACT [doi:10.3389/fncir.2020.611841] xref: BTO:0004278 is_a: CL:0000120 ! granule cell @@ -12906,6 +13200,7 @@ id: CL:0001042 name: T-helper 22 cell def: "CD4-positive, alpha-beta T cell that produces IL-22." [GOC:dsd, PMID:19578368, PMID:19578369] comment: TH22 cells are also reportedly CCR4-positive, CCR6-positive, CCR10-positive, CXCR3-negative. TH22 cells are reportedly capable of secreting IL-13. +subset: cellxgene_subset synonym: "helper T cell type 22" EXACT [] synonym: "T(H)-22 cell" EXACT [] synonym: "Th22 cell" EXACT [] @@ -12923,6 +13218,7 @@ id: CL:0001043 name: activated CD4-positive, alpha-beta T cell, human def: "A recently activated CD4-positive, alpha-beta T cell with the phenotype HLA-DRA-positive, CD38-positive, CD69-positive, CD62L-negative, CD127-negative, and CD25-positive." [GOC:add, PMID:22343568] comment: This cell type is compatible with the HIPC Lyoplate markers for 'activated CD4+ T cell', but includes via logical inference from its parent additional markers known to be expressed on activated CD4+ T cells. The inclusion of HLA-DRA in the definition restricts this definition to human activated CD4+ T cells, as activated mouse T cells do not express MHC class II. +subset: cellxgene_subset synonym: "activated CD4+ T cell" BROAD [PMID:22343568] synonym: "activated CD4-positive, alpha-beta T lymphocyte, human" EXACT [] synonym: "activated CD4-positive, alpha-beta T-cell, human" EXACT [] @@ -12939,6 +13235,7 @@ id: CL:0001044 name: effector CD4-positive, alpha-beta T cell def: "A CD4-positive, alpha-beta T cell with the phenotype CCR7-negative, CD45RA-positive." [GOC:add, PMID:22343568] comment: This cell type is compatible with the HIPC Lyoplate markers for 'effector CD4+ T cell'. The functional characteristics of this cell type currently undefined in CL, which affects its proper placement within the hierarchy. +subset: cellxgene_subset synonym: "effector CD4+ T cell" BROAD [PMID:22343568] synonym: "effector CD4-positive, alpha-beta T lymphocyte" EXACT [] synonym: "effector CD4-positive, alpha-beta T-cell" EXACT [] @@ -13021,6 +13318,7 @@ id: CL:0001049 name: activated CD8-positive, alpha-beta T cell, human def: "A recently activated CD8-positive, alpha-beta T cell with the phenotype HLA-DRA-positive, CD38-positive, CD69-positive, CD62L-negative, CD127-negative, CCR7-negative, and CD25-positive." [GOC:add, PMID:22343568] comment: This cell type is compatible with the HIPC Lyoplate markers for 'activated CD8+ T cell', but includes via logical inference from its parent additional markers known to be expressed on activated CD8+ T cells. The inclusion of HLA-DRA in the definition restricts this definition to human activated CD8+ T cells, as activated mouse T cells do not express MHC class II. +subset: cellxgene_subset synonym: "activated CD8+ T cell" BROAD [PMID:22343568] synonym: "activated CD8-positive, alpha-beta T lymphocyte, human" EXACT [] synonym: "activated CD8-positive, alpha-beta T-cell, human" EXACT [] @@ -13037,6 +13335,7 @@ id: CL:0001050 name: effector CD8-positive, alpha-beta T cell def: "A CD8-positive, alpha-beta T cell with the phenotype CCR7-negative, CD45RA-positive." [GOC:add, PMID:22343568] comment: This cell type is compatible with the HIPC Lyoplate markers for 'effector CD8+ T cell'. The functional characteristics of this cell type currently undefined in CL, which affects its proper placement within the hierarchy. +subset: cellxgene_subset subset: human_reference_atlas synonym: "effector CD8+ T cell" BROAD [PMID:22343568] synonym: "effector CD8-positive, alpha-beta T lymphocyte" EXACT [] @@ -13102,6 +13401,7 @@ id: CL:0001054 name: CD14-positive monocyte def: "A monocyte that expresses CD14 and is negative for the lineage markers CD3, CD19, and CD20." [GOC:add, PMID:22343568] comment: This cell type is compatible with the HIPC Lyoplate markers for 'monocyte'. Note that while CD14 is considered a reliable marker for human monocytes, it is only expressed on approximately 85% of mouse monocytes. +subset: cellxgene_subset subset: human_reference_atlas synonym: "monocyte" NARROW [PMID:22343568] is_a: CL:0000576 ! monocyte @@ -13137,6 +13437,7 @@ id: CL:0001056 name: dendritic cell, human def: "A dendritic cell with the phenotype HLA-DRA-positive." [GOC:add, PMID:22343568] comment: This cell type is compatible with the HIPC Lyoplate markers for 'dendritic cell'. The inclusion of HLA-DRA in the definition restricts this definition to human dendritic cells. +subset: cellxgene_subset subset: human_reference_atlas synonym: "dendritic cell" BROAD [PMID:22343568] is_a: CL:0000451 ! dendritic cell @@ -13150,6 +13451,7 @@ id: CL:0001057 name: myeloid dendritic cell, human def: "A myeloid dendritic cell with the phenotype HLA-DRA-positive." [GOC:add, PMID:22343568] comment: This cell type is compatible with the HIPC Lyoplate markers for 'myeloid dendritic cell'. The inclusion of HLA-DRA in the definition restricts this definition to human myeloid dendritic cells. +subset: cellxgene_subset synonym: "myeloid dendritic cell" BROAD [PMID:22343568] is_a: CL:0000782 ! myeloid dendritic cell is_a: CL:0001056 ! dendritic cell, human @@ -13161,6 +13463,7 @@ id: CL:0001058 name: plasmacytoid dendritic cell, human def: "A plasmacytoid dendritic cell with the phenotype HLA-DRA-positive, CD123-positive, and CD11c-negative." [GOC:add, PMID:22343568] comment: This cell type is compatible with the HIPC Lyoplate markers for 'plasmacytoid dendritic cell'. The inclusion of HLA-DRA in the definition restricts this definition to human plasmacytoid dendritic cells. +subset: cellxgene_subset subset: human_reference_atlas synonym: "plasmacytoid dendritic cell" BROAD [PMID:22343568] is_a: CL:0000784 ! plasmacytoid dendritic cell @@ -13243,6 +13546,7 @@ id: CL:0001061 name: abnormal cell def: "A cell found in an organism or derived from an organism exhibiting a phenotype that deviates from the expected phenotype of any native cell type of that organism. Abnormal cells are typically found in disease states or disease models." [GOC:add, GOC:cg, GOC:wdd] comment: https://github.com/obophenotype/cell-ontology/issues/448 +subset: cellxgene_subset xref: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C12913 is_a: CL:0000000 ! cell intersection_of: CL:0000000 ! cell @@ -13256,6 +13560,7 @@ id: CL:0001062 name: effector memory CD8-positive, alpha-beta T cell, terminally differentiated def: "A CD8-positive, alpha beta memory T cell with the phenotype CD45RA-positive, CD45RO-negative, and CCR7-negative." [GOC:add, GOC:dos, PMID:15032595, PMID:16237082, PMID:26883338] comment: This cell type is seen in human but not found in the mouse. +subset: cellxgene_subset subset: human_reference_atlas synonym: "CD8+ TEMRA" EXACT [PMID:15032595] synonym: "CD8-positive TEMRA" EXACT [PMID:15032595] @@ -13280,6 +13585,7 @@ id: CL:0001063 name: neoplastic cell def: "An abnormal cell exhibiting dysregulation of cell proliferation or programmed cell death and capable of forming a neoplasm, an aggregate of cells in the form of a tumor mass or an excess number of abnormal cells (liquid tumor) within an organism." [GOC:add, GOC:cg, GOC:wdd] comment: https://github.com/obophenotype/cell-ontology/issues/448 +subset: cellxgene_subset synonym: "tumor cell" RELATED [] synonym: "tumour cell" RELATED [] xref: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C12922 @@ -13295,6 +13601,7 @@ id: CL:0001064 name: malignant cell def: "A neoplastic cell that is capable of entering a surrounding tissue" [GOC:add, GOC:cg, GOC:wdd] comment: https://github.com/obophenotype/cell-ontology/issues/448 +subset: cellxgene_subset synonym: "cancer cell" RELATED [] xref: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C12917 is_a: CL:0001063 ! neoplastic cell @@ -13309,6 +13616,7 @@ id: CL:0001065 name: innate lymphoid cell def: "A lymphocyte that lacks characteristic T cell, B cell, myeloid cell, and dendritic cell markers, that functions as part of the innate immune response to produce cytokines and other effector responses." [GOC:add, GOC:dsd, PMID:23292121, PMID:23348417] subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas is_a: CL:0000542 ! lymphocyte intersection_of: CL:0000542 ! lymphocyte @@ -13328,6 +13636,7 @@ property_value: dcterms-date "2017-01-30T20:20:48Z" xsd:dateTime id: CL:0001066 name: erythroid progenitor cell, mammalian def: "A progenitor cell committed to the erythroid lineage. This cell is ter119-positive but lacks expression of other hematopoietic lineage markers (lin-negative)." [GOC:add, ISBN:0721601464] +subset: cellxgene_subset synonym: "BFU-E" RELATED OMO:0003000 [] synonym: "blast forming unit erythroid" RELATED [] synonym: "burst forming unit erythroid" RELATED [] @@ -13390,6 +13699,7 @@ property_value: dcterms-date "2017-01-30T20:54:12Z" xsd:dateTime id: CL:0001069 name: group 2 innate lymphoid cell def: "An innate lymphoid cell that is capable of producing T-helper 2-cell associated cytokines upon stimulation." [GOC:add, GOC:dsd, PMID:23292121, PMID:23562755] +subset: cellxgene_subset subset: human_reference_atlas synonym: "ILC2" EXACT [] synonym: "natural helper cell" EXACT [] @@ -13422,6 +13732,7 @@ relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens id: CL:0001071 name: group 3 innate lymphoid cell def: "An innate lymphoid cell that constituitively expresses RORgt and is capable of expressing IL17A and/or IL-22." [GOC:add, GOC:dsd, PMID:23292121, PMID:23348417] +subset: cellxgene_subset subset: human_reference_atlas synonym: "ILC3" EXACT [] is_a: CL:0001065 ! innate lymphoid cell @@ -13468,6 +13779,7 @@ relationship: RO:0002104 PR:P13591 ! has plasma membrane part neural cell adhesi id: CL:0001074 name: CD34-positive, CD56-positive, CD117-positive common innate lymphoid precursor, human def: "An innate lymphoid cell precursor in the human with the phenotype CD34-positive, CD56-positive, CD117-positive.Thie cell type may include precusors to NK cells and ILC3 cells." [GOC:add, PMID:30193847] +subset: cellxgene_subset synonym: "CD34-positive, CD56-positive, CD117-positive CILP" EXACT [] is_a: CL:0001082 ! immature innate lymphoid cell intersection_of: CL:0001065 ! innate lymphoid cell @@ -13496,6 +13808,7 @@ relationship: RO:0002104 PR:Q96E93 ! has plasma membrane part killer cell lectin id: CL:0001076 name: NKp46-positive innate lymphoid cell, human def: "An innate lymphoid cell in the human with the phenotype NKp46-positive that is a precusor for NK cells and ILC3 cells." [GOC:add, PMID:31201208, PMID:31337734] +subset: cellxgene_subset synonym: "NKp46-positive ILC" EXACT [] is_a: CL:0001074 ! CD34-positive, CD56-positive, CD117-positive common innate lymphoid precursor, human intersection_of: CL:0001074 ! CD34-positive, CD56-positive, CD117-positive common innate lymphoid precursor, human @@ -13507,6 +13820,7 @@ relationship: RO:0002104 PR:O76036 ! has plasma membrane part natural cytotoxici id: CL:0001077 name: ILC1, human def: "An ILC1 cell in the human with the phenotype CD56-negative, IL-7Ralpha-positive, T-bet-positive." [GOC:add, PMID:31500958] +subset: cellxgene_subset synonym: "innate lymphoid cell 1, human" EXACT [] is_a: CL:0001068 ! ILC1 intersection_of: CL:0001068 ! ILC1 @@ -13521,6 +13835,7 @@ relationship: RO:0002104 PR:P16871 ! has plasma membrane part interleukin-7 rece id: CL:0001078 name: group 3 innate lymphoid cell, human def: "A group 3 innate lymphoid cell in the human with the phenotype IL-7Ralpha-positive." [GOC:add, PMID:31500958] +subset: cellxgene_subset subset: human_reference_atlas synonym: "ILC3, human" EXACT [] is_a: CL:0001071 ! group 3 innate lymphoid cell @@ -13535,6 +13850,7 @@ relationship: RO:0002104 PR:P16871 ! has plasma membrane part interleukin-7 rece id: CL:0001079 name: NKp44-positive group 3 innate lymphoid cell, human def: "A group 3 innate lymphoid cell in the human with the phenotype IL-7Ralpha-positive, and NKp44-positive." [GOC:add, PMID:24778151, PMID:31500958] +subset: cellxgene_subset is_a: CL:0001078 ! group 3 innate lymphoid cell, human intersection_of: CL:0001071 ! group 3 innate lymphoid cell intersection_of: in_taxon NCBITaxon:9606 ! Homo sapiens @@ -13546,6 +13862,7 @@ relationship: RO:0002104 PR:O95944 ! has plasma membrane part natural cytotoxici id: CL:0001080 name: NKp44-negative group 3 innate lymphoid cell, human def: "A group 3 innate lymphoid cell in the human with the phenotype IL-7Ralpha-positive, and NKp44-negative." [GOC:add, PMID:24778151, PMID:31500958] +subset: cellxgene_subset is_a: CL:0001078 ! group 3 innate lymphoid cell, human intersection_of: CL:0001071 ! group 3 innate lymphoid cell intersection_of: CL:4030046 PR:O95944 ! lacks_plasma_membrane_part natural cytotoxicity triggering receptor 2 (human) @@ -13557,6 +13874,7 @@ relationship: CL:4030046 PR:O95944 ! lacks_plasma_membrane_part natural cytotoxi id: CL:0001081 name: group 2 innate lymphoid cell, human def: "A group 2 innate lymphoid cell in the human with the phenotype CD25-positive, CD127-positive, CD161-positive, and GATA-3-positive." [GOC:add, PMID:24778151, PMID:26844414] +subset: cellxgene_subset synonym: "ILC2, human" EXACT [] is_a: CL:0001069 ! group 2 innate lymphoid cell intersection_of: CL:0001069 ! group 2 innate lymphoid cell @@ -13577,6 +13895,7 @@ relationship: RO:0002104 PR:Q9Y5Y4 ! has plasma membrane part prostaglandin D2 r id: CL:0001082 name: immature innate lymphoid cell def: "An innate lyphoid cell with an immature phenotype." [GOC:add] +subset: cellxgene_subset synonym: "immature ILC" EXACT [] is_a: CL:0001065 ! innate lymphoid cell intersection_of: CL:0001065 ! innate lymphoid cell @@ -13657,6 +13976,7 @@ relationship: RO:0002104 PR:000001412 ! has plasma membrane part CD86 molecule id: CL:0001203 name: CD8-positive, alpha-beta memory T cell, CD45RO-positive def: "A CD8-positive, alpha-beta T cell with memory phenotype indicated by being CD45RO and CD127-positive. This cell type is also described as being CD25-negative, CD44-high, and CD122-high." [GO_REF:0000031, GOC:tfm, PMID:20146720] +subset: cellxgene_subset subset: human_reference_atlas synonym: "CD8-positive, alpha-beta memory T lymphocyte, CD45RO-positive" EXACT [] synonym: "CD8-positive, alpha-beta memory T-cell, CD45RO-positive" EXACT [] @@ -13892,6 +14212,7 @@ creation_date: 2010-01-14T03:25:17Z id: CL:0002009 name: macrophage dendritic cell progenitor def: "A progenitor cell that can give rise to plasmacytoid and myeloid dendritic cells, and to monocytes and macrophages." [GOC:tfm, PMID:19273628] +subset: cellxgene_subset synonym: "MDP" EXACT [] is_a: CL:0000763 ! myeloid cell is_a: CL:0002032 {is_inferred="true"} ! hematopoietic oligopotent progenitor cell @@ -13909,6 +14230,7 @@ creation_date: 2010-01-19T02:51:58Z id: CL:0002010 name: pre-conventional dendritic cell def: "A lin-negative, MHC-II-negative, CD11c-positive, FLT3-positive cell with intermediate expression of SIRP-alpha." [GOC:tfm] +subset: cellxgene_subset is_a: CL:0000763 ! myeloid cell is_a: CL:0002031 {is_inferred="true"} ! hematopoietic lineage restricted progenitor cell is_a: PR:000050567 ! protein-containing material entity @@ -14251,6 +14573,7 @@ id: CL:0002028 name: basophil mast progenitor cell def: "A cell type that can give rise to basophil and mast cells. This cell is CD34-positive, CD117-positive, CD125-positive, FceRIa-negative, and T1/ST2-negative, and expresses Gata-1, Gata-2, C/EBPa" [GOC:ak, GOC:dsd, GOC:tfm, PMCID:PMC1312421] comment: There may be an intermediate cell type. These cells also CD13-positive, CD16-positive, CD32-positive, and integrin beta 7-positive. Transcription factors: GATA1-positive, MCP-1-positive, mitf-positive, PU.1-positive, and CEBP/a-low. +subset: cellxgene_subset synonym: "BMCP" EXACT [] is_a: CL:0000763 ! myeloid cell is_a: CL:0002191 ! granulocytopoietic cell @@ -14434,6 +14757,7 @@ creation_date: 2009-10-20T02:20:43Z id: CL:0002038 name: T follicular helper cell def: "A CD4-positive, CXCR5-positive, CCR7-negative alpha-beta T cell located in follicles of secondary lymph nodes that is BCL6-high, ICOS-high and PD1-high, and stimulates follicular B cells to undergo class-switching and antibody production." [GOC:tfm, PMID:19855402, PMID:20107805, PMID:22043829] +subset: cellxgene_subset subset: human_reference_atlas synonym: "follicular B helper T cell" RELATED [PMID:22043829] synonym: "follicular helper T cell" RELATED [PMID:22649468] @@ -14583,6 +14907,7 @@ id: CL:0002045 name: fraction A pre-pro B cell def: "A pro-B cell that is CD45R/B220-positive, CD43-positive, HSA-low, BP-1-negative and Ly6c-negative. This cell type is also described as being lin-negative, AA4-positive, Kit-positive, IL7Ra-positive and CD45R-positive." [GOC:ak, GOC:tfm, http://www.immgen.org/index_content.html, PMID:12633665, PMID:17582343] comment: Markers associated with mouse cells. +subset: cellxgene_subset synonym: "fraction A" BROAD [] synonym: "pre pro B cell" RELATED [] is_a: CL:0000826 {is_inferred="true"} ! pro-B cell @@ -14609,6 +14934,7 @@ id: CL:0002046 name: early pro-B cell def: "A pro-B cell that is CD22-positive, CD34-positive, CD38-positive and TdT-positive (has TdT activity). Pre-BCR is expressed on the cell surface. Cell is CD19-negative, CD20-negative, complement receptor type 2-negative and CD10-low. D-to-J recombination of the heavy chain occurs at this stage." [GOC:dsd, GOC:tfm, PMID:18432934] comment: Markers are commonly associated with human cells. These cells are also reportedly CD21-negative. Transcription factors: PU.1-positive, Ikaros-positive, E2A-positive, and PAX5-positive. +subset: cellxgene_subset is_a: CL:0000826 {is_inferred="true"} ! pro-B cell intersection_of: CL:0000826 ! pro-B cell intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule @@ -14655,6 +14981,7 @@ id: CL:0002048 name: late pro-B cell def: "A pre-B cell precursor is CD19-low, CD22-positive , CD34-positive, CD38-positive." [GOC:dsd, GOC:tfm, PMID:18432934] comment: Late pro-B cells are also reportedly CD10-positive, CD20-negative, CD21-negative, and TdT-positive. Transcription factors: PU.1-positive, Ikaros-positive, E2A-positive, and PAX5-positive. +subset: cellxgene_subset is_a: CL:0000817 {is_inferred="true"} ! precursor B cell intersection_of: CL:0000817 ! precursor B cell intersection_of: RO:0002104 PR:000001003 ! has plasma membrane part CD34 molecule @@ -14849,6 +15176,7 @@ id: CL:0002057 name: CD14-positive, CD16-negative classical monocyte def: "A classical monocyte that is CD14-positive, CD16-negative, CD64-positive, CD163-positive." [GOC:add, GOC:tfm, PMID:15615263, PMID:1706877, PMID:19689341, PMID:22343568] comment: This cell type is compatible with the HIPC Lyoplate markers for 'CD16- monocyte'. The markers used in the definition are associated with human monocytes. +subset: cellxgene_subset synonym: "CD16- monocyte" EXACT [PMID:22343568] synonym: "CD16-negative monocyte" EXACT [] is_a: CL:0000860 {is_inferred="true"} ! classical monocyte @@ -14933,6 +15261,7 @@ creation_date: 2010-06-22T11:18:44Z id: CL:0002062 name: type I pneumocyte def: "A type I pneumocyte is a flattened, branched pneumocyte that covers more than 98% of the alveolar surface. This large cell has thin (50-100 nm) cytoplasmic extensions to form the air-blood barrier essential for normal gas exchange." [GOC:tfm, http://www.copewithcytokines.de, PMID:20054144] +subset: cellxgene_subset subset: human_reference_atlas synonym: "AT1" EXACT [] synonym: "ATI" EXACT [] @@ -14960,6 +15289,7 @@ creation_date: 2010-06-23T04:37:54Z id: CL:0002063 name: type II pneumocyte def: "A type II pneumocyte is a pneumocyte that modulates the fluid surrounding the alveolar epithelium by secreting and recycling surfactants. This cell type also contributes to tissue repair and can differentiate after injury into a type I pneumocyte. Thicker than squamous alveolar cells, have a rounded apical surface that projects above the level of surrounding epithelium. The free surface is covered by short microvilli." [GOC:tfm, http://www.copewithcytokines.de, ISBN:0412046911, PMID:8540632] +subset: cellxgene_subset subset: human_reference_atlas synonym: "AT2" EXACT [] synonym: "ATII" EXACT [] @@ -14992,6 +15322,7 @@ creation_date: 2010-06-24T12:04:13Z id: CL:0002064 name: pancreatic acinar cell def: "A secretory cell found in pancreatic acini that secretes digestive enzymes and mucins. This cell is a typical zymogenic cell, have a basal nucleus and basophilic cytoplasm consisting of regular arrays of granular endoplasmic reticulum with mitochondria and dense secretory granules." [GOC:tfm, http://www.copewithcytokines.de/cope.cgi?key=pancreatic%20acinar%20cells, ISBN:0517223651, PMID:20395539] +subset: cellxgene_subset subset: human_reference_atlas synonym: "acinar cell of pancreas" EXACT [] xref: BTO:0000028 @@ -15075,6 +15406,7 @@ creation_date: 2010-06-29T09:58:19Z id: CL:0002071 name: enterocyte of epithelium of large intestine def: "Columnar cell which populate the epithelium of large intestine and absorb water. This cell is the most numerous of the epithelial cell types in the large intestine; bear apical microvilli, contain secretory granules in their apical cytoplasm; secretion appears to be largely mucins, but is also rich in antibodies of the IgA type." [GOC:tfm, ISBN:0517223651] +subset: cellxgene_subset subset: human_reference_atlas synonym: "columnar cell" BROAD [] synonym: "columnar cell of the colon" EXACT [] @@ -15128,6 +15460,7 @@ creation_date: 2010-06-29T11:50:47Z id: CL:0002075 name: brush cell of trachebronchial tree def: "Infrequent type of columnar epithelial cell. This cell is characterized by the presence of a tuft of blunt, squat microvilli (approximately 120-140/cell) on the cell surface. The microvilli contain filaments that stretch into the underlying cytoplasm. They have a distinctive pear shape with a wide base and a narrow microvillous apex. Function not known." [GOC:tfm, ISBN:0517223651, PMID:15817800] +subset: cellxgene_subset synonym: "pulmonary brush cell" RELATED [] is_a: CL:0002202 ! epithelial cell of tracheobronchial tree is_a: CL:0002204 ! brush cell @@ -15175,6 +15508,7 @@ creation_date: 2010-06-29T03:49:14Z id: CL:0002079 name: pancreatic ductal cell def: "Epithelial cell found in the ducts of the pancreas. This cell type contributes to the high luminal pH." [FMA:63099, GOC:tfm, PMID:14740223] +subset: cellxgene_subset subset: human_reference_atlas xref: FMA:63099 is_a: CL:0000069 ! branched duct epithelial cell @@ -15263,6 +15597,7 @@ id: CL:0002085 name: tanycyte alt_id: CL:0000643 def: "Specialized elongated ventricular ependymal cell that has processes that extend to the outer, or pial, surface of the CNS. Resemble spongioblasts seen in developing brain. Found in the adult brain in the third ventricle, cerebral aqueduct, spinal canal and floor of the fourth ventricle." [GOC:tfm, http://neurolex.org/wiki/Category\:Tanycyte] +subset: cellxgene_subset synonym: "stretch cell" EXACT [] xref: BTO:0001953 xref: FMA:54560 @@ -15298,6 +15633,7 @@ id: CL:0002088 name: interstitial cell of Cajal def: "This is a cell found in the gastrointestinal tract of mammals and serves as a pacemaker that triggers gut contraction. ICCs mediate inputs from the enteric nervous system to smooth muscle cells and are thought to be the cells from which gastrointestinal stromal tumors (GISTs) arise." [GOC:tfm, PMID:16460275, PMID:19520112] comment: Some argue this cell type is of mesenchymal origin. +subset: cellxgene_subset subset: human_reference_atlas synonym: "ICC" EXACT [] synonym: "intestinal pacemaker cell" EXACT [GOC:pr] @@ -15387,6 +15723,7 @@ id: CL:0002092 name: bone marrow cell def: "A cell found in the bone marrow. This can include fibroblasts, macrophages, adipocytes, osteoblasts, osteoclasts, endothelial cells and hematopoietic cells." [GOC:tfm, ISBN:0618947256] comment: MH consider whether bone marrow cells are bone cells in the structural sense vs. being part of bone organ sense. +subset: cellxgene_subset xref: BTO:0004850 xref: FMA:83621 xref: MESH:D001854 @@ -15415,6 +15752,7 @@ creation_date: 2010-08-23T09:50:01Z id: CL:0002094 name: interstitial cell of ovary def: "A cell that makes up the loose connective tissue of the ovary." [GOC:tfm] +subset: cellxgene_subset xref: FMA:18709 is_a: CL:0002132 ! stromal cell of ovary relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 @@ -15450,6 +15788,7 @@ creation_date: 2010-08-23T11:24:11Z id: CL:0002097 name: cortical cell of adrenal gland def: "A cell of the adrenal cortex. Cell types include those that synthesize and secrete chemical derivatives (steroids) of cholesterol." [GOC:tfm] +subset: cellxgene_subset synonym: "adrenal cortex cell" EXACT [] synonym: "adrenocortical cell" EXACT [] xref: FMA:69545 @@ -15722,6 +16061,7 @@ relationship: RO:0015016 PR:000001014 ! has low plasma membrane amount receptor- id: CL:0002117 name: IgG-negative class switched memory B cell def: "A class switched memory B cell that lacks IgG on the cell surface." [GOC:dsd, GOC:rhs, GOC:tfm, PMID:20123131] +subset: cellxgene_subset synonym: "IgG- class switched memory B cell" EXACT [] synonym: "IgG- class switched memory B lymphocyte" EXACT [] synonym: "IgG- class switched memory B-cell" EXACT [] @@ -15889,6 +16229,7 @@ relationship: RO:0015015 PR:000001201 ! has high plasma membrane amount C-C chem id: CL:0002129 name: regular atrial cardiac myocyte def: "Regular cardiac myocyte of a cardiac atrium." [GOC:tfm] +subset: cellxgene_subset synonym: "atrial cardiac muscle cell" EXACT [GOC:pr] synonym: "atrial myocyte" EXACT [] synonym: "regular atrial cardiac muscle fiber" EXACT [] @@ -15911,6 +16252,7 @@ creation_date: 2010-08-23T11:41:09Z id: CL:0002131 name: regular ventricular cardiac myocyte def: "Regular cardiac myocyte of a cardiac ventricle." [GOC:tfm] +subset: cellxgene_subset synonym: "regular cardiac muscle cell of ventricle" EXACT [] synonym: "regular ventricular cardiac muscle fiber" EXACT [] synonym: "ventricular cardiac muscle cell" BROAD [GOC:pr] @@ -15924,6 +16266,7 @@ creation_date: 2010-08-23T11:41:13Z id: CL:0002132 name: stromal cell of ovary def: "A stomal cell of the ovary" [GOC:tfm] +subset: cellxgene_subset synonym: "ovarian stromal cell" EXACT [GOC:cjm] xref: FMA:72299 is_a: CL:0000499 ! stromal cell @@ -15990,6 +16333,7 @@ id: CL:0002138 name: endothelial cell of lymphatic vessel alt_id: CL:1000421 def: "A endothelial cell of a lymphatic vessel. The border of the oak leaf-shaped endothelial cell of initial lymphatics are joined by specialized buttons. The discontinuous feature of buttons distinguishes them from zippers in collecting lymphatics, but both types of junctions are composed of proteins typical of adherens junctions and tight junctions found in the endothelium of blood vessels. Buttons seal the sides of flaps of the oak leaf-shaped endothelial cell, leaving open the tips of flaps as routes for fluid entry without disassembly and reformation of intercellular junctions." [GOC:tfm, PMID:17846148] +subset: cellxgene_subset subset: human_reference_atlas synonym: "LEC" EXACT [] synonym: "lymphatic endothelial cell" EXACT [] @@ -16010,6 +16354,7 @@ id: CL:0002139 name: endothelial cell of vascular tree def: "An endothelial cell of the vascular tree, which includes blood vessels and lymphatic vessels." [GOC:dsd, GOC:tfm, PMID:12768659] comment: These cells are reportedly CD31-positive, CD34-positive, CD144-positive, TAL1-positive. +subset: cellxgene_subset synonym: "cubodial endothelial cell of vascular tree" NARROW [] synonym: "vascular endothelial cell" EXACT [] xref: BTO:0001854 @@ -16071,6 +16416,7 @@ creation_date: 2010-08-24T02:18:36Z id: CL:0002144 name: capillary endothelial cell def: "An endothelial cell found in capillaries." [GOC:tfm] +subset: cellxgene_subset subset: human_reference_atlas xref: BTO:0004956 xref: CALOHA:TS-0112 @@ -16087,6 +16433,7 @@ creation_date: 2010-08-24T10:15:00Z id: CL:0002145 name: ciliated columnar cell of tracheobronchial tree def: "A ciliated columnar cell found in the trachea and bronchus. Vary from low to tall columnar; possesses up to 300 cilia at its surface, interspersed with long irregular microvilli with the cilia varying in length from about 6um in the trachea to about 4um in the terminal bronchioles; driving force of the ciliary current in the bronchial tree." [GOC:tfm, ISBN:0517223651] +subset: cellxgene_subset subset: human_reference_atlas xref: FMA:70542 is_a: CL:0002202 ! epithelial cell of tracheobronchial tree @@ -16139,6 +16486,7 @@ id: CL:0002149 name: epithelial cell of uterus alt_id: CL:1000294 def: "An epithelial cell of the uterus." [GOC:tfm] +subset: cellxgene_subset xref: FMA:256161 is_a: CL:0002076 {is_inferred="true"} ! endo-epithelial cell intersection_of: CL:0002076 ! endo-epithelial cell @@ -16164,6 +16512,7 @@ creation_date: 2010-08-24T03:48:30Z id: CL:0002151 name: late promyelocyte def: "A promyelocyte that is considerably smaller, with more condensed chromatin, and nucleoli are no longer conspicuous." [ISBN:0412046911] +subset: cellxgene_subset xref: FMA:83534 is_a: CL:0000836 ! promyelocyte relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 @@ -16198,6 +16547,7 @@ creation_date: 2010-08-24T10:53:03Z id: CL:0002154 name: early promyelocyte def: "A promyelocyte with a nucleus that is indented and contains more marginated heterochromatin compared to its precursor cell (myeloblast); cytoplasm is deeply basophilic and contains numerous mitochondria and meandering cysternae of endoplasmic reticulum; largest of the granulocyte lineages." [FMA:0412046911, GOC:tfm] +subset: cellxgene_subset xref: FMA:83533 is_a: CL:0000836 ! promyelocyte relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 @@ -16217,6 +16567,7 @@ creation_date: 2010-08-24T03:15:21Z id: CL:0002157 name: endosteal cell def: "A cell type that makes up the highly vascular membrane lining the marrow cavity of long bones." [FMA:0618947256, GOC:tfm] +subset: cellxgene_subset xref: FMA:86495 is_a: CL:0001035 ! bone cell is_a: CL:0002078 ! meso-epithelial cell @@ -16459,6 +16810,7 @@ creation_date: 2010-08-25T03:22:08Z id: CL:0002179 name: foveolar cell of stomach def: "An epithelial cell within one of the pits in the embryonic gastric mucosa from which the gastric glands develop ." [GOC:tfm, http://www.merriam-webster.com/medical/foveolar] +subset: cellxgene_subset xref: FMA:86552 is_a: CL:0002178 ! epithelial cell of stomach relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 @@ -16533,6 +16885,7 @@ id: CL:0002187 name: basal cell of epidermis alt_id: CL:1000439 def: "A basally situated, mitotically active, columnar-shaped keratinocyte attached to the basement membrane." [GOC:tfm, ISBN:0517223651] +subset: cellxgene_subset xref: FMA:70571 is_a: CL:0000312 ! keratinocyte is_a: CL:0000646 {is_inferred="true"} ! basal cell @@ -16547,6 +16900,7 @@ creation_date: 2010-08-26T03:12:49Z id: CL:0002188 name: glomerular endothelial cell def: "An endothelial cell found in the glomerulus of the kidney. This cell is flattened, highly fenestrated, and plays a vital role in the formation of glomerular ultrafiltrate." [GOC:tfm, PMID:15840009] +subset: cellxgene_subset subset: kidney_upper_slim xref: BTO:0004632 xref: FMA:70970 @@ -16562,6 +16916,7 @@ creation_date: 2010-08-26T10:59:44Z id: CL:0002189 name: granular cell of epidermis def: "A keratinocyte of the epidermis that is characterized by containing granules of keratohyalin and lamellar granules." [ISBN:1416031855] +subset: cellxgene_subset xref: FMA:70543 is_a: CL:0000312 ! keratinocyte relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 @@ -16580,6 +16935,7 @@ creation_date: 2010-08-26T03:37:02Z id: CL:0002191 name: granulocytopoietic cell def: "A cell involved in the formation of a granulocyte." [GOC:tfm] +subset: cellxgene_subset xref: FMA:83519 is_a: CL:0000839 {is_inferred="true"} ! myeloid lineage restricted progenitor cell intersection_of: CL:0000839 ! myeloid lineage restricted progenitor cell @@ -16603,6 +16959,7 @@ creation_date: 2010-08-30T01:08:15Z id: CL:0002193 name: myelocyte def: "A cell type that is the first of the maturation stages of the granulocytic leukocytes normally found in the bone marrow. Granules are seen in the cytoplasm. The nuclear material of the myelocyte is denser than that of the myeloblast but lacks a definable membrane. The cell is flat and contains increasing numbers of granules as maturation progresses." [GOC:tfm, http://en.wikipedia.org/wiki/Myelocyte, ISBN:0323052908] +subset: cellxgene_subset subset: human_reference_atlas xref: BTO:0000734 xref: FMA:83525 @@ -16704,6 +17061,7 @@ creation_date: 2010-09-02T11:33:26Z id: CL:0002201 name: renal beta-intercalated cell def: "A renal intercalated cell that secretes base and reabsorbs acid in the distal segments of the kidney tubule to maintain acid/base balance." [GOC:tfm, PMID:11781354, PMID:25632105] +subset: cellxgene_subset subset: human_reference_atlas synonym: "type B intercalated cell" EXACT [PMID:25632105] synonym: "type B-IC" EXACT [PMID:25632105] @@ -16731,6 +17089,7 @@ name: brush cell of epithelium proper of large intestine alt_id: CL:1000387 def: "Brush cell found in the epithelial layer of the colon." [GOC:tfm] comment: Brush cells are a distinct cell type from brush border cell-types. +subset: cellxgene_subset synonym: "brush cell of large intestine" EXACT [http://orcid.org/0000-0003-4183-8865] synonym: "tuft cell of epithelium of large intestine" EXACT [http://orcid.org/0000-0003-4183-8865] synonym: "tuft cell of large intestine" EXACT [http://orcid.org/0000-0003-4183-8865] @@ -16746,6 +17105,7 @@ creation_date: 2010-09-02T02:20:50Z id: CL:0002204 name: brush cell def: "A cell type found in the gastrointestinal and respiratory tracts that is characterized by the presence of a tuft of blunt, squat microvilli (120-140 per cell). Function of this cell type is not known." [GOC:tfm, ISBN:0517223651, PMID:15817800] +subset: cellxgene_subset synonym: "caveolated cell" EXACT [] synonym: "fibrillovesicular cell" EXACT [] synonym: "multivesicular cell" EXACT [] @@ -16788,6 +17148,7 @@ id: CL:0002207 name: brush cell of trachea alt_id: CL:1000388 def: "Brush cell of the epithelium in the trachea." [GOC:tfm] +subset: cellxgene_subset subset: human_reference_atlas xref: FMA:263224 is_a: CL:0000307 {is_inferred="true"} ! tracheal epithelial cell @@ -16979,6 +17340,7 @@ creation_date: 2010-09-07T10:38:03Z id: CL:0002223 name: anterior lens cell def: "A cell of the transparent layer of simple cuboidal epithelium over the anterior surface of the lens; transform into lens fiber(s)." [GOC:tfm, ISBN:0517223651] +subset: cellxgene_subset xref: FMA:63181 is_a: CL:0002224 ! lens epithelial cell relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 @@ -16988,6 +17350,7 @@ creation_date: 2010-09-07T10:45:45Z id: CL:0002224 name: lens epithelial cell def: "A cell of the cuboidal epithelium that covers the lens. The cells of the lens epithelium regulate most of the homeostatic functions of the lens. As ions, nutrients, and liquid enter the lens from the aqueous humor, Na+/K+ ATPase pumps in the lens epithelial cells pump ions out of the lens to maintain appropriate lens osmolarity and volume, with equatorially positioned lens epithelium cells contributing most to this current. The activity of the Na+/K+ ATPases keeps water and current flowing through the lens from the poles and exiting through the equatorial regions. The cells of the lens epithelium also serve as the progenitors for new lens fibers. It constantly lays down fibers in the embryo, fetus, infant, and adult, and continues to lay down fibers for lifelong growth." [GOC:tfm, http://en.wikipedia.org/wiki/Lens_%28anatomy%29#Lens_epithelium, ISBN:0721662544] +subset: cellxgene_subset subset: human_reference_atlas xref: FMA:67559 is_a: CL:0000075 {is_inferred="true"} ! columnar/cuboidal epithelial cell @@ -17003,6 +17366,7 @@ creation_date: 2010-09-07T10:45:47Z id: CL:0002225 name: secondary lens fiber def: "A lens fiber cell that develops from primary lens fiber; located towards the center of lens; cell organelles are normally degraded or in the process of being degraded." [GOC:tfm, ISBN:0517223651] +subset: cellxgene_subset subset: human_reference_atlas synonym: "secondary lens fibre" EXACT [] is_a: CL:0011004 ! lens fiber cell @@ -17060,6 +17424,7 @@ name: epithelial cell of prostate alt_id: CL:1000295 alt_id: CL:1000408 def: "An epithelial cell of the prostate." [GOC:tfm] +subset: cellxgene_subset synonym: "prostate epithelial cell" EXACT [] xref: FMA:256163 xref: FMA:66817 @@ -17130,6 +17495,7 @@ id: CL:0002236 name: basal epithelial cell of prostatic duct alt_id: CL:1000463 def: "A cell that constitutes the basal layer of epithelium in the prostatic duct." [GOC:tfm, PMID:15226377] +subset: cellxgene_subset xref: FMA:74226 is_a: CL:0000068 ! duct epithelial cell is_a: CL:0002341 ! basal cell of prostate epithelium @@ -17199,6 +17565,7 @@ creation_date: 2010-09-07T02:25:18Z id: CL:0002241 name: pulmonary interstitial fibroblast def: "A fibroblasts found in interstitial spaces in the pulmonary tract. Greater numbers of these cells are found in idiopathic pulmonary fibrosis." [GOC:tfm] +subset: cellxgene_subset synonym: "pulmonary myofibroblast" EXACT [] synonym: "pulmonary septal cell" EXACT [] xref: FMA:84467 @@ -17227,6 +17594,7 @@ creation_date: 2010-09-07T03:32:33Z id: CL:0002243 name: smooth muscle cell of sphincter of pupil def: "A circular smooth muscle cell of the iris, innervated by the ciliary nerves (parasympathetic), and acting to contract the pupil. This muscle cell derives from neuroectoderm. This smooth muscle cell results from transformation of epithelial cells to smooth muscle cells." [GOC:tfm, ISBN:0721662544, ISBN:0721694128] +subset: cellxgene_subset synonym: "smooth muscle fiber of sphincter of pupil" EXACT [] synonym: "smooth muscle fibre of sphincter of pupil" RELATED [] xref: FMA:70611 @@ -17307,6 +17675,7 @@ creation_date: 2010-09-07T04:40:32Z id: CL:0002250 name: intestinal crypt stem cell def: "A cell that is found in a zone occupying the bottom region of the crypt; provide the source of most of the cell types of the intestinal epithelium; proliferate by mitotic division; differentiates into columnar or goblet cells." [GOC:tfm, ISBN:0517223651] +subset: cellxgene_subset synonym: "stem cell of intestinal crypt of Lieberkuhn" EXACT [] xref: FMA:63379 is_a: CL:0000048 ! multi fate stem cell @@ -17333,6 +17702,7 @@ id: CL:0002252 name: epithelial cell of esophagus alt_id: CL:1000402 def: "An epithelial cell of the esophagus." [GOC:tfm] +subset: cellxgene_subset xref: FMA:63071 is_a: CL:0002251 {is_inferred="true"} ! epithelial cell of alimentary canal intersection_of: CL:0000066 ! epithelial cell @@ -17346,6 +17716,7 @@ id: CL:0002253 name: epithelial cell of large intestine alt_id: CL:1000292 def: "An epithelial cell of the large intestine." [GOC:tfm] +subset: cellxgene_subset synonym: "epithelial cell of colon" RELATED [] xref: BTO:0004297 xref: FMA:256157 @@ -17361,6 +17732,7 @@ id: CL:0002254 name: epithelial cell of small intestine alt_id: CL:1000293 def: "An epithelial cell of the small intestine." [GOC:tfm] +subset: cellxgene_subset xref: FMA:256159 is_a: CL:0002563 {is_inferred="true"} ! intestinal epithelial cell intersection_of: CL:0002563 ! intestinal epithelial cell @@ -17417,6 +17789,7 @@ creation_date: 2010-09-08T01:46:51Z id: CL:0002258 name: thyroid follicular cell def: "A cell type that varies from squamous to columnar, depending on their activity with microvillus directed luminally. This cell produces and secretes thyroid hormones." [GOC:tfm, ISBN:0517223651] +subset: cellxgene_subset synonym: "follicular cell of thyroid gland" EXACT [] synonym: "principal cell of thyroid gland" EXACT [] synonym: "thyroid gland follicular cell" EXACT [] @@ -17431,6 +17804,7 @@ creation_date: 2010-09-08T01:50:08Z id: CL:0002259 name: neuroepithelial stem cell def: "The stem cell from which glial precursor cell arises from." [GOC:tfm, PMID:11687496] +subset: cellxgene_subset synonym: "totipotent neuroepithelial stem cell" NARROW [] xref: FMA:87171 is_a: CL:0000723 ! somatic stem cell @@ -17465,6 +17839,7 @@ id: CL:0002262 name: endothelial cell of sinusoid alt_id: CL:1000403 def: "An endothelial cell that lines any of the venous cavities through which blood passes in various glands and organs such as the spleen and liver." [GOC:tfm, ISBN:0618947256] +subset: cellxgene_subset subset: human_reference_atlas xref: FMA:63134 is_a: CL:0000115 ! endothelial cell @@ -17545,6 +17920,7 @@ creation_date: 2010-09-10T01:36:03Z id: CL:0002268 name: P/D1 enteroendocrine cell def: "An enteroendocrine cell that stores and secretes Ghrelin." [GOC:tfm, ISBN:0517223651, PMID:15153415] +subset: cellxgene_subset xref: FMA:63418 is_a: CL:0000164 ! enteroendocrine cell is_a: CL:0002269 ! vasoactive intestinal peptide secreting cell @@ -17614,6 +17990,7 @@ id: CL:0002275 name: pancreatic PP cell def: "A PP cell located in the islets of the pancreas." [GOC:tfm] comment: The term PP cell of pancreatic acinus was obsoleted due to a lack of evidence, making PP cell of pancreatic islets synonymous with pancreatic PP cell. +subset: cellxgene_subset subset: human_reference_atlas synonym: "pancreatic polypeptide-secreting cell" EXACT [] synonym: "PP cell of pancreatic islet" EXACT [] @@ -17645,6 +18022,7 @@ creation_date: 2010-09-10T03:30:33Z id: CL:0002277 name: type I enteroendocrine cell def: "An enteroendocrine cell commonest in the duodenum and jejunum, rare in ileum, that secretes cholecystokinin. This cell type is involved in the regulation of digestive enzymes and bile." [GOC:tfm] +subset: cellxgene_subset synonym: "CCK cell" EXACT [] xref: FMA:62937 is_a: CL:0000164 ! enteroendocrine cell @@ -17656,6 +18034,7 @@ creation_date: 2010-09-10T03:44:36Z id: CL:0002278 name: GIP cell def: "An enteroendocrine cell of duodenum and jejunum that produces gastric inhibitory peptide." [GOC:tfm] +subset: cellxgene_subset synonym: "type K enteroendocrine cell" EXACT [] xref: FMA:62942 is_a: CL:0000167 ! peptide hormone secreting cell @@ -17667,6 +18046,7 @@ creation_date: 2010-09-10T03:51:47Z id: CL:0002279 name: type L enteroendocrine cell def: "A enteroendocrine cell type that is numerous in ileum, present in jejunum and large intestine, few in duodenum. This cell type produces glucagon-like immunoreactants (glicentin, glucagon-37, glucagon-29, GLP-1 and -2) and PYY." [ISBN:0517223651, PMID:15153415] +subset: cellxgene_subset xref: FMA:62944 is_a: CL:0000164 ! enteroendocrine cell is_a: CL:0000167 ! peptide hormone secreting cell @@ -17677,6 +18057,7 @@ creation_date: 2010-09-10T03:59:09Z id: CL:0002280 name: type N enteroendocrine cell def: "An enteroendocrine cell found in the ileum and jejunum that produces neurotensin." [GOC:tfm] +subset: cellxgene_subset synonym: "N cell" EXACT [] xref: FMA:62943 is_a: CL:0000164 ! enteroendocrine cell @@ -17823,6 +18204,7 @@ id: CL:0002293 name: epithelial cell of thymus alt_id: CL:1000459 def: "An epithelial cell of the thymus. Epithelial reticular cells are pleomorphic, stellate, non-phagocytic cells which seem to be supportive in function and are held together by desmosomes. They replace the fibroblastoid reticular cells found in other lymphoid organs. Other epithelial cells in the medulla have the ultrastructure of secretory cells. Although different epithelial cells throughout the thymus appear alike by light microscopy their ultrastructure and function varies." [FMA:72208, GOC:tfm] +subset: cellxgene_subset synonym: "epithelial cell of thymus gland" EXACT [] synonym: "epithelial reticular cell" EXACT [] synonym: "epithelial reticular cell of thymus" EXACT [] @@ -17949,6 +18331,7 @@ id: CL:0002303 name: pigmented ciliary epithelial cell def: "A cell that is part of pigmented ciliary epithelium. This cell type uptakes sodium and chloride ions from stromal interstitium and passes the ions to non-pigmented ciliary epithelial cells via gap junctions." [PMID:15106942] comment: In a consensus model of unidirectional secretion, aqueous humour is formed by transferring solute, principally NaCl, from stroma to posterior chamber, with water passively following the osmotic gradient. Unidirectional secretion comprises three sequential steps. First, NaCl is transferred from the stromal interstitium into the pigmented ciliary epithelial (PE) cells. Second, solute passes from the PE into the non-pigmented ciliary epithelial (NPE) cells through gap junctions. Finally, NPE cells release Na+ and Cl− into the aqueous humour. {xref="https://doi.org/10.1016/j.exer.2003.09.021"} +subset: cellxgene_subset subset: eye_upper_slim subset: human_reference_atlas synonym: "PE cell" EXACT [https://doi.org/10.1016/j.exer.2003.09.021] @@ -17964,6 +18347,7 @@ id: CL:0002304 name: non-pigmented ciliary epithelial cell def: "A cell that is part of non-pigmented ciliary epithelium. This cell type participates in aqueous humor formation by releasing solute, principally sodium and chloride ions received from pigmented epithelial cells via gap junctions, into the aqueous humor of the eye." [GOC:tfm, PMID:15106942] comment: In a consensus model of unidirectional secretion, aqueous humour is formed by transferring solute, principally NaCl, from stroma to posterior chamber, with water passively following the osmotic gradient. Unidirectional secretion comprises three sequential steps. First, NaCl is transferred from the stromal interstitium into the pigmented ciliary epithelial (PE) cells. Second, solute passes from the PE into the non-pigmented ciliary epithelial (NPE) cells through gap junctions. Finally, NPE cells release Na+ and Cl− into the aqueous humour. {xref="https://doi.org/10.1016/j.exer.2003.09.021"} +subset: cellxgene_subset subset: eye_upper_slim subset: human_reference_atlas synonym: "nonpigmented ciliary epithelial cell" EXACT [PMID:10913011] @@ -17994,6 +18378,7 @@ relationship: part_of UBERON:0004135 ! distal tubule id: CL:0002306 name: epithelial cell of proximal tubule def: "An epithelial cell of the proximal tubule of the kidney." [GOC:tfm, ISBN:1-4160-2328-3] +subset: cellxgene_subset subset: human_reference_atlas subset: kidney_upper_slim synonym: "kidney proximal tubule epithelial cell" EXACT [] @@ -18159,6 +18544,7 @@ creation_date: 2010-09-15T10:47:11Z id: CL:0002319 name: neural cell def: "A cell that is part of the nervous system." [GOC:tfm, ISBN:0618947256] +subset: cellxgene_subset xref: CALOHA:TS-2040 xref: FMA:70333 is_a: CL:0000000 ! cell @@ -18173,6 +18559,7 @@ id: CL:0002320 name: connective tissue cell alt_id: CL:1000406 def: "A cell of the supporting or framework tissue of the body, arising chiefly from the embryonic mesoderm and including adipose tissue, cartilage, and bone." [GOC:tfm, ISBN:0618947256] +subset: cellxgene_subset xref: CALOHA:TS-2096 xref: FMA:63875 xref: MESH:D003239 @@ -18199,6 +18586,7 @@ id: CL:0002322 name: embryonic stem cell def: "A stem cell of embryonic origin." [GOC:dsd, GOC:tfm, ISBN:068340007X, PMID:18179856] comment: This is an in vitro cell type and may be removed in future releases. These cells are reportedly SSEA-4-positive, CD73-negative, and CD324-positive. +subset: cellxgene_subset synonym: "ESC" EXACT [] xref: BTO:0001086 xref: CALOHA:TS-0263 @@ -18225,6 +18613,7 @@ creation_date: 2010-09-20T10:13:37Z id: CL:0002324 name: myoepithelial cell of mammary gland def: "A myoepithelial cell that surrounds milk-secreting luminal epithelial cells. This cell type contracts under the stimulation of oxytocin and is attached to the basement membrane by hemidesmosomes and to the adjacent luminal cells by desmosomes. This cell type expresses high level of keratin-14 and is estrogen receptor alpha negative." [GOC:tfm, PMID:11250738, PMID:19022771] +subset: cellxgene_subset synonym: "basal cell of lactiferous duct" EXACT [FMA:67800] synonym: "myoepithelial cell of lactiferous gland" EXACT [] xref: CALOHA:TS-2378 @@ -18242,6 +18631,7 @@ name: lactocyte alt_id: CL:0002230 alt_id: CL:1000476 def: "A milk-producing glandular epithelial cell that is part of a mammary gland alveolus and differentiates from a luminal adaptive secretory precursor cell during secretory differentiation (also termed lactogenesis I). Following secretory activation (also termed lactogenesis II), a lactocyte is involved in the synthesis and/or transport of milk constituents including proteins, oligosaccharides, lactose, micronutrients, fat, hormones, immunoglobulins, and cytokines into the lumen of the lactating mammary gland." [doi:10.1177/156482659601700404, GOC:tfm, PMID:19022771, PMID:28717367, PMID:35091553, PMID:35377806] +subset: cellxgene_subset synonym: "epithelial cell of lactiferous gland" EXACT [] synonym: "lactaction-associated mammary epithelial cell" EXACT [PMID:35091553] synonym: "lactation-derived mammary cell" EXACT [PMID:35091553] @@ -18268,6 +18658,7 @@ creation_date: 2010-09-20T01:30:57Z id: CL:0002326 name: luminal epithelial cell of mammary gland def: "A mammary epithelial cell that occurs in the lumen of the ductal and alveoli structure in the breast." [GOC:tfm, PMID:19022771] +subset: cellxgene_subset synonym: "mature luminal cell" BROAD [PMID:21930782] xref: FMA:73280 is_a: CL:0000069 ! branched duct epithelial cell @@ -18280,6 +18671,7 @@ creation_date: 2010-09-20T01:37:53Z id: CL:0002327 name: mammary gland epithelial cell def: "An epithelial cell of the mammary gland." [GOC:tfm, PMID:19022771] +subset: cellxgene_subset synonym: "breast epithelial cell" EXACT [] synonym: "mammary epithelial cell" EXACT [] xref: BTO:0004300 @@ -18294,6 +18686,7 @@ creation_date: 2010-09-20T01:49:37Z id: CL:0002328 name: bronchial epithelial cell def: "An epithelial cell of the bronchus." [GOC:tfm] +subset: cellxgene_subset xref: BTO:0002922 is_a: CL:0002202 ! epithelial cell of tracheobronchial tree intersection_of: CL:0000066 ! epithelial cell @@ -18306,6 +18699,7 @@ creation_date: 2010-09-20T02:00:00Z id: CL:0002329 name: basal epithelial cell of tracheobronchial tree def: "An epithelial cell type that lacks the columnar shape typical for other respiratory epithelial cells. This cell type is able to differentiate into other respiratory epithelial cells in response to injury." [GOC:tfm] +subset: cellxgene_subset subset: human_reference_atlas is_a: CL:0002202 ! epithelial cell of tracheobronchial tree relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 @@ -18324,6 +18718,7 @@ creation_date: 2010-09-20T02:17:58Z id: CL:0002332 name: ciliated cell of the bronchus def: "A ciliated cell of the bronchus." [GOC:tfm, PMID:18757316] +subset: cellxgene_subset subset: human_reference_atlas is_a: CL:0002145 ! ciliated columnar cell of tracheobronchial tree is_a: CL:0002328 ! bronchial epithelial cell @@ -18373,6 +18768,7 @@ creation_date: 2010-09-20T02:52:54Z id: CL:0002337 name: keratinocyte stem cell def: "A stem cell located in the bulge of the hair follicle that can give rise to regenerate the new follicle with each hair cycle and to reepithelialize the epidermis during wound repair." [PMID:15339667] +subset: cellxgene_subset subset: human_reference_atlas synonym: "bulge keratinocyte" EXACT [] is_a: CL:0000048 ! multi fate stem cell @@ -18387,6 +18783,7 @@ id: CL:0002338 name: CD56-positive, CD161-positive immature natural killer cell, human def: "A natural killer cell that is developmentally immature, has the phenotype CD34-negative, CD56-positive, CD117-positive, CD122-positive,and CD161-positive." [GO_REF:0000031, GOC:add, ISBN:0781735149, PMID:12457618] comment: Human markers; killer cell immunoglobulin-like receptor 2DL1 is used as a representative example (PRO at this time lacks a KIR superfamily). +subset: cellxgene_subset synonym: "p-NK" RELATED [PMID:12457618] is_a: CL:0000823 ! immature natural killer cell intersection_of: CL:0000823 ! immature natural killer cell @@ -18422,6 +18819,7 @@ creation_date: 2010-09-20T03:21:06Z id: CL:0002340 name: luminal cell of prostate epithelium def: "The exocrine cell of the prostate, this epithelial cell secretes prostatic acid phosphotase and PSA, and is dependent on androgen hormones for survival." [GOC:tfm] +subset: cellxgene_subset subset: human_reference_atlas is_a: CL:0002231 ! epithelial cell of prostate relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 @@ -18432,6 +18830,7 @@ creation_date: 2010-09-20T03:34:05Z id: CL:0002341 name: basal cell of prostate epithelium def: "An undifferentiated cell of the prostate epithelium that lacks secretory activity." [GOC:tfm, PMCID:PMC2673349] +subset: cellxgene_subset subset: human_reference_atlas is_a: CL:0002231 ! epithelial cell of prostate relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 @@ -18450,6 +18849,7 @@ creation_date: 2010-09-20T03:49:58Z id: CL:0002343 name: decidual natural killer cell, human def: "A natural killer cell subset that is found in the decidual of the uterus and is CD56-high, Galectin-1-positive and CD16-negative. This cell type represents the most abundant immune cell type in the decidual during the first trimester of pregnancy." [PMID:14568979, PMID:19800965] +subset: cellxgene_subset subset: human_reference_atlas synonym: "decidual NK cell" EXACT [] synonym: "dNK cell" EXACT [] @@ -18583,6 +18983,7 @@ id: CL:0002350 name: endocardial cell alt_id: CL:1000475 def: "An endothelial cell that lines the intracavitary lumen of the heart, separating the circulating blood from the underlying myocardium. This cell type releases a number of vasoactive substances including prostacyclin, nitrous oxide and endothelin." [GOC:tfm, ISSN:0452-3458] +subset: cellxgene_subset subset: human_reference_atlas synonym: "endocardial endothelial cell" EXACT [] synonym: "endothelial cell of endocardium" EXACT [FMA:75621] @@ -18599,6 +19000,7 @@ creation_date: 2010-09-21T04:33:05Z id: CL:0002351 name: progenitor cell of endocrine pancreas def: "A progenitor cell that is able to differentiate into the pancreas alpha, beta and delta endocrine cells. This cell type expresses neurogenin-3 and Isl-1." [GOC:tfm, PMID:20025937, PMID:20217494, PMID:22728667] +subset: cellxgene_subset synonym: "pancreatic endocrine progenitor" EXACT [] synonym: "pancreatic islet progenitor cell" EXACT [] is_a: CL:0011026 ! progenitor cell @@ -18671,6 +19073,7 @@ creation_date: 2010-09-22T09:08:34Z id: CL:0002355 name: primitive red blood cell def: "A large nucleated basophilic erythrocyte found in mammalian embryos. This cell type arises from the blood islands of yolk sacs and expresses different types of hemoglobins (beta-H1, gamma-1 and zeta) than adult erythrocytes. Considered a type of erythroblast as this cell type can enucleate in circulation." [DOI:10.1097/MOH.0b013e3282f97ae1, GOC:tfm, PMID:11495698] +subset: cellxgene_subset synonym: "primitive erythroblast" EXACT [] synonym: "primitive erythrocyte" EXACT [] synonym: "primitive erythroid cell" EXACT [] @@ -18783,6 +19186,7 @@ creation_date: 2010-09-22T01:40:44Z id: CL:0002363 name: keratocyte def: "A keratocyte is a specialized fibroblast residing in the cornea stroma that has a flattened, dendritic morphology; located between the lamellae with a large flattened nucleus, and lengthy processes which communicate with neighboring cells. This corneal layer, representing about 85-90% of corneal thickness, is built up from highly regular collagenous lamellae and extracellular matrix components. Keratocytes play the major role in keeping it transparent, healing its wounds, and synthesizing its components. This cell type secretes collagen I, V, VI, and keratan sulfate." [GOC:tfm, ISBN:9780702029585] +subset: cellxgene_subset subset: eye_upper_slim subset: human_reference_atlas synonym: "corneal fibroblast" EXACT [] @@ -18799,6 +19203,7 @@ creation_date: 2010-09-22T01:57:40Z id: CL:0002364 name: cortical thymic epithelial cell def: "An epithelial cell of the cortical portion of the thymus. Epithelial cells in this region are required for positive selection of CD8-positive T cells." [GOC:tfm, PMID:18403190] +subset: cellxgene_subset subset: human_reference_atlas synonym: "cTEC" EXACT [] xref: BTO:0004562 @@ -18814,6 +19219,7 @@ creation_date: 2010-09-23T03:17:12Z id: CL:0002365 name: medullary thymic epithelial cell def: "An epithelial cell of the medullary thymus. This cell type expresses a diverse range of tissue-specific antigens. This promiscuous gene expression is a cell-autonomous property of medullary epithelial cells and is maintained during the entire period of thymic T cell output." [GOC:tfm, PMID:18180458] +subset: cellxgene_subset synonym: "mTEC" EXACT [] xref: BTO:0004563 is_a: CL:0002293 ! epithelial cell of thymus @@ -18827,6 +19233,7 @@ creation_date: 2010-09-23T03:17:14Z id: CL:0002366 name: myometrial cell def: "A smooth muscle cell of the myometrium that enlarges and stretches during pregnancy, and contracts in response to oxytocin." [GOC:tfm, PMID:11429640] +subset: cellxgene_subset synonym: "myometrium smooth muscle cell" EXACT [] xref: BTO:0004519 is_a: CL:0002601 ! uterine smooth muscle cell @@ -18852,6 +19259,7 @@ creation_date: 2010-09-23T04:18:50Z id: CL:0002368 name: respiratory epithelial cell def: "An endo-epithelial cell of the respiratory tract." [GOC:tfm] +subset: cellxgene_subset synonym: "airway epithelial cell" EXACT [] xref: BTO:0004533 is_a: CL:0002076 {is_inferred="true"} ! endo-epithelial cell @@ -18874,6 +19282,7 @@ creation_date: 2010-10-01T09:02:42Z id: CL:0002370 name: respiratory goblet cell def: "A simple columnar epithelial cell that secretes mucin. Rough endoplasmic reticulum, mitochondria, the nucleus, and other organelles are concentrated in the basal portion. The apical plasma membrane projects microvilli to increase surface area for secretion." [GOC:tfm, ISBN:0721662544] +subset: cellxgene_subset synonym: "respiratory mucosa goblet cells" EXACT [MP:0010863] is_a: CL:0000160 ! goblet cell intersection_of: CL:0000160 ! goblet cell @@ -18886,12 +19295,13 @@ creation_date: 2010-09-23T04:42:27Z id: CL:0002371 name: obsolete somatic cell def: "OBSOLETE. A cell of an organism that does not pass on its genetic material to the organism's offspring (i.e. a non-germ line cell)." [GOC:tfm, ISBN:0721662544] -comment: https://github.com/obophenotype/cell-ontology/issues/1150 +subset: cellxgene_subset subset: ubprop:upper_level xref: BTO:0001268 xref: FMA:72300 xref: WBbt:0008378 relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 +relationship: term_tracker_item https://github.com/obophenotype/cell-ontology/issues/1150 is_obsolete: true replaced_by: CL:0000000 creation_date: 2010-09-24T09:44:42Z @@ -18941,6 +19351,7 @@ creation_date: 2010-09-24T01:49:31Z id: CL:0002375 name: Schwann cell precursor def: "A giioblast cell that develops from a migratory neural crest cell. The SCP is embedded among neurons (axons) with minimal extracellular spaces separating them from nerve cell membranes and has no basal lamina. In rodents SCPs are the only cells in the Schwann cell linage that expresses Cdh19." [GOC:tfm] +subset: cellxgene_subset synonym: "Schwann cell precursor cell" EXACT [] is_a: CL:0000030 ! glioblast is_a: CL:0011026 ! progenitor cell @@ -18962,6 +19373,7 @@ creation_date: 2010-09-24T02:10:26Z id: CL:0002377 name: immature Schwann cell def: "A glial cell that develops from a Schwann cell precursor. The immature Schwann cell is embedded among neurons (axons) with minimal extracellular spaces separating them from nerve cell membranes and has a basal lamina. Cells can survive without an axon present. Immature Schwann cell can be found communally ensheathing large groups of axons." [GOC:cvs, GOC:tfm, ISBN:0721662544] +subset: cellxgene_subset synonym: "Schwann cell" BROAD [] xref: ZFA:0001725 is_a: CL:0002573 ! Schwann cell @@ -19099,6 +19511,7 @@ replaced_by: PO:0025017 id: CL:0002393 name: intermediate monocyte def: "A monocyte that has characteristics of both patrolling and inflammatory monocytes." [GOC:tfm, PMID:20628149, PMID:20870168] +subset: cellxgene_subset is_a: CL:0000576 ! monocyte intersection_of: CL:0000576 ! monocyte intersection_of: CL:4030044 GO:0030224 ! has_not_completed monocyte differentiation @@ -19120,6 +19533,7 @@ id: CL:0002394 name: CD141-positive myeloid dendritic cell def: "A myeloid dendritic cell found in the blood, lymph nodes, tonsil, bone marrow, and spleen that is CD141-positive (BDCA-3), XCR1-positive, and Clec9A-positive. This cell-type can cross-present antigen to CD8-positive T cells and can produce inteferon-beta." [GOC:dsd, GOC:tfm, PMCID:PMC2882828, PMCID:PMC2882837, PMID:17332250, PMID:20628149] comment: Markers are found in human cells. Normally they represent 3-5% of peripheral blood mDCs (human). These cells express high levels of CD283 (TLR3), are capable of producing IL-12p70 and IFN-beta upon stimulation, and inducing a TH1 response [PMCID:PMC2882828]. They are also Necl2-positive. May be human equivalent of murine CD8alpha-positive DCs. +subset: cellxgene_subset subset: human_reference_atlas is_a: CL:0000782 {is_inferred="true"} ! myeloid dendritic cell is_a: CL:0000784 ! plasmacytoid dendritic cell @@ -19161,6 +19575,7 @@ id: CL:0002396 name: CD14-low, CD16-positive monocyte def: "A patrolling monocyte that is CD14-low and CD16-positive." [GOC:tfm, PMID:20870168] comment: Markers are associated with human monocytes. +subset: cellxgene_subset subset: human_reference_atlas synonym: "non-classical monocyte, human" EXACT [] is_a: CL:0000875 {is_inferred="true"} ! non-classical monocyte @@ -19180,6 +19595,7 @@ id: CL:0002397 name: CD14-positive, CD16-positive monocyte def: "A CD14-positive monocyte that is also CD16-positive and CCR2-negative." [GOC:tfm, PMID:20628149, PMID:21937707, PMID:22343568] comment: This cell type is compatible with the HIPC Lyoplate markers for 'CD16+ monocyte'. Markers are associated with human cells. Note that this cell type encompasses both human intermediate monocytes (CD14+, CD16-low), and human non-classical monocytes (CD14-low, CD16+). +subset: cellxgene_subset synonym: "CD16+ monocyte" EXACT [PMID:22343568] is_a: CL:0001054 ! CD14-positive monocyte intersection_of: CL:0001054 ! CD14-positive monocyte @@ -19212,6 +19628,7 @@ id: CL:0002399 name: CD1c-positive myeloid dendritic cell def: "A myeloid dendritic cell found in the blood that is CD1c-positive." [GOC:dsd, GOC:tfm, PMID:20204387, PMID:20628149] comment: Normally represent 10-20% of peripheral blood mDCs (human). They are also CD281-positive (TLR1), CD282-positive (TLR2), CD283-positive (TLR3), CD284-positive (TLR4), CD285-positive (TLR5), CD286-positive (TLR6), CD288-positive (TLR8), and CD290-positive (TLR10) [PMID:20204387]. Upon TLR stimulation, these cells were potent producers of CXCL8 (IL-8), while producing little TNF-alpha. +subset: cellxgene_subset subset: human_reference_atlas is_a: CL:0000782 {is_inferred="true"} ! myeloid dendritic cell intersection_of: CL:0000782 ! myeloid dendritic cell @@ -19356,6 +19773,7 @@ creation_date: 2010-10-07T02:59:08Z id: CL:0002410 name: pancreatic stellate cell def: "A cell that is found in the periacinar space of the exocrine pancreas and in perivascular and periductal regions of the pancreas, and has long cytoplasmic processes that encircle the base of the acinus. Expresses several intermediate filament proteins including vimentin and nestin. Shares many of the characteristics of hepatatic stellate cells, but not stellate cells of the central nervous system. Upon activation, this cell type undergoes morphological and gene expression changes that make the cell suggestive of being a type of myofibroblast." [GOC:mah, GOC:tfm, PMID:17200706] +subset: cellxgene_subset subset: human_reference_atlas synonym: "pancreas stellate cell" EXACT [] synonym: "PaSC" EXACT [] @@ -19442,6 +19860,7 @@ creation_date: 2010-10-12T12:21:16Z id: CL:0002419 name: mature T cell def: "A T cell that expresses a T cell receptor complex and has completed T cell selection." [GOC:tfm] +subset: cellxgene_subset synonym: "CD3e-positive T cell" EXACT [] synonym: "CD3epsilon T cell" RELATED [] synonym: "mature T-cell" EXACT [] @@ -19459,6 +19878,7 @@ id: CL:0002420 name: immature T cell def: "A T cell that has not completed T cell selection." [GOC:tfm] subset: blood_and_immune_upper_slim +subset: cellxgene_subset synonym: "immature T-cell" EXACT [] xref: BTO:0001372 xref: CALOHA:TS-1042 @@ -19484,6 +19904,7 @@ creation_date: 2010-10-15T09:24:05Z id: CL:0002422 name: enucleated reticulocyte def: "A reticulocyte lacking a nucleus and showing a basophilic reticulum under vital staining due to the presence of ribosomes." [GOC:tfm, ISBN:0-12203-052-4, ISBN:0721601464] +subset: cellxgene_subset xref: CALOHA:TS-0864 xref: FMA:66785 is_a: CL:0000225 ! anucleate cell @@ -19525,6 +19946,7 @@ id: CL:0002425 name: early T lineage precursor def: "A pro-T cell that is lin-negative, CD25-negative, CD127-negative, CD44-positive and kit-positive." [GOC:dsd, GOC:tfm, http://www.immgen.org/index_content.html, PMID:16551251] comment: ETPs are reportedly CD1a-negative, CD4-negative, CD7-positive, CD8a-negative, CD8b-negative, CD33-low, CD34-high, CD38-low, CD45RA-positive, and CD45RO-negative. +subset: cellxgene_subset subset: human_reference_atlas synonym: "ETP" EXACT [] synonym: "preT.ETP.Th" EXACT [] @@ -19930,6 +20352,7 @@ id: CL:0002453 name: oligodendrocyte precursor cell def: "A progenitor cell of the central nervous system that can differentiate into oligodendrocytes or type-2 astrocytes. This cell originates from multiple structures within the developing brain including the medial ganglion eminence and the lateral ganglionic eminence. These cells migrate throughout the central nervous system and persist into adulthood where they play an important role in remyelination of injured neurons." [GOC:tfm, PMID:10704434, PMID:11756508, PMID:20142420, PMID:2182078, PMID:24133281, PMID:9826671] comment: This cell type can be purified from optic nerves and other regions of the embryonic, postnatal and adult rat CNS and can be differentiated in vitro to oligodendrocytes and type-2 astrocytes. Some references use the terms 'oligodendrocyte precursor cell' and 'oligodendrocyte type-2 astrocyte (O-2A) progenitor' to refer to the same entity (e.g., PMID:10704434), while others describe an oligodendrocyte type-2 astrocyte (O-2A) progenitor cell as the precurosr to oligodendrocyte- and type-2 astrocyte- progenitor cells (e.g, ISBN:9780702028991). {xref="PMID:10704434", xref="ISBN:9780702028991", xref="PMID:2182078"} +subset: cellxgene_subset subset: human_reference_atlas synonym: "O-2A/OPC" RELATED OMO:0003000 [PMID:24133281] synonym: "O2A/OPC" RELATED OMO:0003000 [PMID:11756508] @@ -19989,6 +20412,7 @@ creation_date: 2010-11-22T01:23:07Z id: CL:0002457 name: epidermal Langerhans cell def: "A Langerhans cell that is in the epidermis and is CD45-positive, MHCII-positive, and CD11b-positive." [GOC:tfm, http://www.immgen.org/index_content.html] +subset: cellxgene_subset subset: human_reference_atlas is_a: CL:0000453 {is_inferred="true"} ! Langerhans cell is_a: CL:0002465 ! CD11b-positive dendritic cell @@ -20167,6 +20591,7 @@ creation_date: 2010-11-23T03:27:12Z id: CL:0002470 name: MHC-II-positive classical monocyte def: "Gr1-high monocyte that has a MHC-II receptor complex." [GOC:tfm, http://www.immgen.org/index_content.html] +subset: cellxgene_subset synonym: "Mo.6c+II" EXACT [] is_a: CL:0002395 {is_inferred="true"} ! Gr1-high classical monocyte intersection_of: CL:0002395 ! Gr1-high classical monocyte @@ -20312,6 +20737,7 @@ creation_date: 2010-11-23T04:35:53Z id: CL:0002480 name: nasal mucosa goblet cell def: "A goblet cell located in the nasal epithelium." [GOC:cjm, GOC:tfm] +subset: cellxgene_subset xref: MP:0002262 is_a: CL:0002370 ! respiratory goblet cell intersection_of: CL:0000160 ! goblet cell @@ -20403,6 +20829,7 @@ creation_date: 2010-12-06T02:53:30Z id: CL:0002488 name: trophoblast giant cell def: "A trophoblast cell that has a large volume of cytoplasm, is polyploid and is usually mononuclear but is also occasionally multi-nucleate. This cell type is important in establishing maternal physiology and remodeling of the vasculature of the placenta." [GOC:tfm, MP:0001714, MP:19876834] +subset: cellxgene_subset synonym: "giant trophoblast cell" EXACT [] is_a: CL:0000351 {is_inferred="true"} ! trophoblast cell intersection_of: CL:0000351 ! trophoblast cell @@ -20418,6 +20845,7 @@ id: CL:0002489 name: double negative thymocyte def: "A thymocyte that lacks expression of CD4 and CD8." [GOC:tfm, MP:0002407] comment: These are precursors to mature T cells; normally, they do not circulate, but are found in the thymus and they have not undergone rearrangement of the alpha and beta T cell receptor genes. +subset: cellxgene_subset synonym: "CD4-CD8- T cell" EXACT [MP:0002407] synonym: "double negative T cell" EXACT [] is_a: CL:0000893 ! thymocyte @@ -20490,6 +20918,7 @@ creation_date: 2010-12-07T09:37:22Z id: CL:0002495 name: fetal cardiomyocyte def: "A fetal and neonatal heart cell that undergoes proliferation and is not yet terminally differentiated into a binucleate or a multinucleate cardiac myocyte." [GOC:tfm, MP:0008788] +subset: cellxgene_subset synonym: "embryonic cardiomyocyte" EXACT [] synonym: "neonatal cardiomyocyte" EXACT [] is_a: CL:0000746 ! cardiac muscle cell @@ -20500,6 +20929,7 @@ creation_date: 2010-12-07T09:50:41Z id: CL:0002496 name: intraepithelial lymphocyte def: "A T cell that is located in the intestinal epithelium and is capable of a mucosal immune response." [GOC:tfm, MP:0008894] +subset: cellxgene_subset synonym: "IEL" EXACT [] synonym: "intraepithelial T cell" EXACT [] synonym: "intraepithelial T-cell" EXACT [] @@ -20572,6 +21002,7 @@ creation_date: 2010-12-07T03:55:49Z id: CL:0002503 name: adventitial cell def: "A cell of the adventitial layer of ductal structures such as the uterer, defent duct, biliary duct, etc" [GOC:tfm] +subset: cellxgene_subset xref: BTO:0002441 xref: FMA:84639 is_a: CL:0000630 ! supporting cell @@ -20586,6 +21017,7 @@ creation_date: 2010-12-07T04:03:56Z id: CL:0002504 name: enteric smooth muscle cell def: "A smooth muscle cell of the intestine." [GOC:tfm] +subset: cellxgene_subset synonym: "intestinal smooth muscle cell" EXACT [] is_a: CL:0000192 {is_inferred="true"} ! smooth muscle cell intersection_of: CL:0000192 ! smooth muscle cell @@ -20774,6 +21206,7 @@ creation_date: 2011-02-08T10:27:05Z id: CL:0002518 name: kidney epithelial cell def: "An epithelial cell of the kidney." [GOC:tfm, KUPO:SJ] +subset: cellxgene_subset xref: KUPO:0001019 is_a: CL:0000066 ! epithelial cell is_a: CL:1000497 {is_inferred="true"} ! kidney cell @@ -20805,6 +21238,7 @@ creation_date: 2011-02-08T01:34:56Z id: CL:0002521 name: subcutaneous adipocyte def: "An adipocyte that is part of subcutaneous adipose tissue." [GOC:tfm] +subset: cellxgene_subset subset: human_reference_atlas synonym: "subcutaneous fat cell" EXACT [] is_a: CL:0000136 {is_inferred="true"} ! adipocyte @@ -21020,6 +21454,7 @@ creation_date: 2011-02-28T12:44:24Z id: CL:0002538 name: intrahepatic cholangiocyte def: "An epithelial cell of the intrahepatic portion of the bile duct. These cells are flattened or cuboidal in shape, and have a small nuclear-to-cytoplasmic ratio relative to large/extrahepatic cholangiocytes." [GOC:tfm, PMID:23720296] +subset: cellxgene_subset synonym: "small bile duct cholangiocyte" EXACT [PMID:23720296] is_a: CL:1000488 {is_inferred="true"} ! cholangiocyte intersection_of: CL:1000488 ! cholangiocyte @@ -21032,6 +21467,7 @@ creation_date: 2011-02-28T01:20:20Z id: CL:0002539 name: aortic smooth muscle cell def: "A smooth muscle cell of the aorta." [GOC:tfm] +subset: cellxgene_subset xref: BTO:0004577 is_a: CL:0019018 ! blood vessel smooth muscle cell intersection_of: CL:0000359 ! vascular associated smooth muscle cell @@ -21069,6 +21505,7 @@ id: CL:0002543 name: vein endothelial cell alt_id: CL:1000393 def: "An endothelial cell that is part of the vein." [GOC:tfm] +subset: cellxgene_subset subset: human_reference_atlas synonym: "endothelial cell of vein" EXACT [] synonym: "venous endothelial cell" EXACT [] @@ -21086,6 +21523,7 @@ creation_date: 2011-02-28T03:48:11Z id: CL:0002544 name: aortic endothelial cell def: "An arterial endothelial cell that is part of the aorta endothelium." [GOC:tfm] +subset: cellxgene_subset xref: BTO:0003245 xref: CALOHA:TS-0047 is_a: CL:1000413 ! endothelial cell of artery @@ -21127,6 +21565,7 @@ creation_date: 2011-02-28T04:43:41Z id: CL:0002548 name: fibroblast of cardiac tissue def: "A fibroblast that is part of the heart." [GOC:tfm] +subset: cellxgene_subset synonym: "cardiac fibroblast" EXACT [] is_a: CL:0000057 {is_inferred="true"} ! fibroblast is_a: CL:0002494 {is_inferred="true"} ! cardiocyte @@ -21183,6 +21622,7 @@ creation_date: 2011-02-28T05:09:12Z id: CL:0002553 name: fibroblast of lung def: "A fibroblast that is part of lung." [GOC:tfm] +subset: cellxgene_subset xref: BTO:0000764 xref: CALOHA:TS-0575 is_a: CL:0000057 {is_inferred="true"} ! fibroblast @@ -21207,6 +21647,7 @@ creation_date: 2011-02-28T05:16:18Z id: CL:0002555 name: fibroblast of mammary gland def: "A fibroblast that is part of the mammary gland." [GOC:tfm] +subset: cellxgene_subset is_a: CL:0000057 {is_inferred="true"} ! fibroblast intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0001911 ! mammary gland @@ -21301,6 +21742,7 @@ creation_date: 2011-03-01T04:31:06Z id: CL:0002563 name: intestinal epithelial cell def: "An epithelial cell of the intestine." [GOC:tfm] +subset: cellxgene_subset is_a: CL:0002251 ! epithelial cell of alimentary canal intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0000160 ! intestine @@ -21380,6 +21822,7 @@ creation_date: 2011-03-01T09:55:12Z id: CL:0002570 name: mesenchymal stem cell of adipose tissue def: "A mesenchymal stem cell of adipose tissue." [GOC:tfm] +subset: cellxgene_subset synonym: "mesenchymal stem cell of adipose" EXACT [] is_a: CL:0000134 ! mesenchymal stem cell intersection_of: CL:0000134 ! mesenchymal stem cell @@ -21416,6 +21859,7 @@ id: CL:0002573 name: Schwann cell def: "A glial cell that myelinates or ensheathes axons in the peripheral nervous system." [GOC:tfm, PMID:16807057] comment: A myelinating Schwann cell wraps around a single axon. Myelination occurs in larger diameter axons, while a process called ensheathment occurs on smaller diameter axons in which a single cell wraps around multiple small, unmyelinated axons separating them with a thin layer of cytoplasm. The structure formed is called a Remak bundle. {xref="PMID:16807057"} +subset: cellxgene_subset subset: human_reference_atlas xref: BTO:0001220 xref: CALOHA:TS-0898 @@ -21552,6 +21996,7 @@ intersection_of: part_of UBERON:0001225 ! cortex of kidney id: CL:0002585 name: retinal blood vessel endothelial cell def: "A blood vessel endothelial cell that is part of the retina." [GOC:tfm] +subset: cellxgene_subset subset: eye_upper_slim subset: human_reference_atlas is_a: CL:0000071 {is_inferred="true"} ! blood vessel endothelial cell @@ -21567,6 +22012,7 @@ creation_date: 2011-03-06T03:28:27Z id: CL:0002586 name: retinal pigment epithelial cell def: "An epithelial cell of the retinal pigmented epithelium." [GOC:tfm] +subset: cellxgene_subset subset: eye_upper_slim subset: human_reference_atlas xref: BTO:0004910 @@ -21620,6 +22066,7 @@ creation_date: 2011-03-06T05:01:20Z id: CL:0002591 name: smooth muscle cell of the pulmonary artery def: "A smooth muscle of the pulmonary artery." [GOC:tfm] +subset: cellxgene_subset subset: human_reference_atlas xref: BTO:0003336 is_a: CL:0019018 ! blood vessel smooth muscle cell @@ -21705,6 +22152,7 @@ creation_date: 2011-03-06T05:43:24Z [Term] id: CL:0002598 name: bronchial smooth muscle cell +subset: cellxgene_subset subset: human_reference_atlas xref: BTO:0004402 is_a: CL:0019019 ! tracheobronchial smooth muscle cell @@ -21730,6 +22178,7 @@ creation_date: 2011-03-06T05:48:17Z id: CL:0002600 name: smooth muscle cell of trachea def: "A smooth muscle cell of the trachea." [GOC:tfm] +subset: cellxgene_subset is_a: CL:0019019 ! tracheobronchial smooth muscle cell intersection_of: CL:0000192 ! smooth muscle cell intersection_of: part_of UBERON:0003126 ! trachea @@ -21741,6 +22190,7 @@ creation_date: 2011-03-06T05:50:28Z id: CL:0002601 name: uterine smooth muscle cell def: "A smooth muscle cell of the uterus." [GOC:tfm] +subset: cellxgene_subset is_a: CL:0000192 {is_inferred="true"} ! smooth muscle cell intersection_of: CL:0000192 ! smooth muscle cell intersection_of: part_of UBERON:0000995 ! uterus @@ -21763,6 +22213,7 @@ creation_date: 2011-03-06T06:50:53Z id: CL:0002603 name: astrocyte of the cerebellum def: "An astrocyte of the cerebellum." [GOC:tfm] +subset: cellxgene_subset is_a: CL:0000127 {is_inferred="true"} ! astrocyte is_a: CL:2000005 ! brain macroglial cell intersection_of: CL:0000127 ! astrocyte @@ -21790,6 +22241,7 @@ creation_date: 2011-03-06T06:57:33Z id: CL:0002605 name: astrocyte of the cerebral cortex def: "An astrocyte of the cerebral cortex." [GOC:tfm] +subset: cellxgene_subset subset: human_reference_atlas is_a: CL:0012000 ! astrocyte of the forebrain is_a: CL:1001579 ! cerebral cortex glial cell @@ -21814,6 +22266,7 @@ creation_date: 2011-03-06T07:11:26Z id: CL:0002607 name: migratory enteric neural crest cell def: "A neural crest cell that gives rise to cells of the enteric nervous system." [GOC:tfm] +subset: cellxgene_subset is_a: CL:0000333 ! migratory neural crest cell relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-03-06T07:24:35Z @@ -21822,6 +22275,7 @@ creation_date: 2011-03-06T07:24:35Z id: CL:0002608 name: hippocampal neuron def: "A neuron with a soma found in the hippocampus." [GOC:tfm] +subset: cellxgene_subset is_a: CL:0010012 ! cerebral cortex neuron intersection_of: CL:0000540 ! neuron intersection_of: RO:0002100 UBERON:0002421 ! has soma location hippocampal formation @@ -21919,6 +22373,7 @@ id: CL:0002617 name: adipocyte of breast def: "An adipocyte that is part of the breast." [GOC:tfm] comment: Adipocytes found in the subcutaneous adipose tissue of breast. The breast consists of three main components, the skin, the subcutaneous adipose tissue and the functional glandular tissue that comprises both parenchyma and stroma.[CALOHA] +subset: cellxgene_subset synonym: "breast adipocyte" EXACT [] synonym: "fat cell of breast" EXACT [] xref: CALOHA:TS-2377 @@ -21959,6 +22414,7 @@ creation_date: 2011-03-14T12:11:18Z id: CL:0002620 name: skin fibroblast def: "A fibroblast of skin." [GOC:tfm] +subset: cellxgene_subset subset: human_reference_atlas xref: BTO:0001255 xref: CALOHA:TS-0935 @@ -21984,6 +22440,7 @@ creation_date: 2011-03-14T12:46:28Z id: CL:0002622 name: prostate stromal cell def: "A stromal cell of the prostate." [GOC:tfm] +subset: cellxgene_subset xref: BTO:0003972 is_a: CL:0000499 {is_inferred="true"} ! stromal cell intersection_of: CL:0000499 ! stromal cell @@ -21996,6 +22453,7 @@ creation_date: 2011-03-14T02:11:10Z id: CL:0002623 name: acinar cell of salivary gland def: "An acinar cell of salivary gland." [GOC:tfm] +subset: cellxgene_subset is_a: CL:0000622 {is_inferred="true"} ! acinar cell is_a: CL:1001596 ! salivary gland glandular cell intersection_of: CL:0000622 ! acinar cell @@ -22038,6 +22496,7 @@ id: CL:0002627 name: mature astrocyte def: "A mature astrocyte that is capable of producing cytokines." [GOC:dsd, PMID:12898703, PMID:8734446] comment: Mature astrocytes are reportedly able to produce aspartate, ATP, BDNF, BMP-2a, BMP-3, CCL2, CCL3, CCL4, CCL5, CCL19, CCL20,CD40L, CNTF, CTGF, CXCL1, CXCL2, CXCL8, edn-1, aFGF, bFGF, G-CSF, glutamate, GM-CSF, IFN-alpha, IFN-beta, IFN-gamma, IGF-1, IL-1alpha, IL-1beta, IL-2, Il-4, IL-6, IL-10, IL-12, LIF, MIP-2, NGF, nitric oxide, NT3, taurine, TGF-beta, TNF-alpha, TNF-beta. +subset: cellxgene_subset synonym: "activated astrocyte" EXACT [] synonym: "mature astrocytic glia" EXACT [] is_a: CL:0000127 ! astrocyte @@ -22057,6 +22516,7 @@ id: CL:0002629 name: mature microglial cell def: "A mature microglial cell that has changed shape to an amoeboid morphology and is capable of cytokine production and antigen presentation." [GOC:dsd, PMID:11517395, PMID:14612429, PMID:15246020, PMID:16177057, PMID:18396103, PMID:20021364] comment: Mature microglia are reportedly CCR2-positive, CD4-positive, CD9-positive, CD11a-positive, CD11b-positive, CD11c-positive, CD13-positive, CD16-positive, CDw17-positive, CD18-positive, CD21-positive, CD26-negative, CD32-positive, CD35-positive, CD36-positive, CD40-positive, CD44-positive, CD45-positive, CD53-positive, CD54-positive, CD56-negative, CD58-positive, CD63-positive, CD64-positive, CD66-positive, CD80-positive, CD86-positive, CD87-positive, CD92-positive, CD106-positive, CD107a-positive, CD147-positive, CD155-positive, CD162-positive, CD163-positive, CD171-negative, CD200R-positive, CXCR3-positive, CX3CR1-positive, fibronectin-positive, GD3-positive, GLUT1-positive, GLUT3-negative, GLUT5-positive, MHCI-positive, MHCII-positive, P2X4-positive, RFD7-negative, RGS5-negative, alpha-SMA-negative, vimentin-positive, and vwf-negative. Mature microglia are capable of producing BDNF, CCL3, CCL5, CCL7, CCL8, CCL9, CCL19, CCL20,CD40L, CSF, CXCL1, CXCL2, CXCL4, CXCL5, CXCL8, CXCL9, CXCL10, glutamate, IL-1beta, IL-1ra, IL-3, IL-6, IL-10, IL-12, LT, MMP-2, MMP-9, NGF, nitric oxide, ROS, TGF-beta, TNF-alpha. +subset: cellxgene_subset synonym: "activated microglia" EXACT [PMID:18396103] synonym: "mature microglia" EXACT [] synonym: "reactive microglia" EXACT [PMID:18396103] @@ -22092,6 +22552,7 @@ creation_date: 2011-06-21T12:28:55Z [Term] id: CL:0002632 name: epithelial cell of lower respiratory tract +subset: cellxgene_subset is_a: CL:0002368 {is_inferred="true"} ! respiratory epithelial cell intersection_of: CL:0002368 ! respiratory epithelial cell intersection_of: part_of UBERON:0001558 ! lower respiratory tract @@ -22103,6 +22564,7 @@ creation_date: 2011-06-21T12:29:31Z id: CL:0002633 name: respiratory basal cell def: "A basal cell in the respiratory tract." [GOC:tfm, PMID:20699479] +subset: cellxgene_subset synonym: "airway basal cell" EXACT [] synonym: "airway basal stem cell" EXACT [] is_a: CL:0000646 ! basal cell @@ -22346,6 +22808,7 @@ creation_date: 2011-07-08T03:54:08Z id: CL:0002657 name: glandular cell of esophagus def: "A glandular epithelial cell of the esophagus." [GOC:tfm] +subset: cellxgene_subset xref: FMA:86548 is_a: CL:0000150 {is_inferred="true"} ! glandular epithelial cell is_a: CL:0002252 {is_inferred="true"} ! epithelial cell of esophagus @@ -22493,6 +22956,7 @@ creation_date: 2011-07-11T03:39:27Z id: CL:0002671 name: endothelial stalk cell def: "An endothelial stalk cell is a specialized endothelial cell that follows behind the tip cell of an angiogenic sprout." [GOC:tfm, PMID:21521739] +subset: cellxgene_subset is_a: CL:0000071 ! blood vessel endothelial cell relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-08-16T01:49:32Z @@ -22510,6 +22974,7 @@ creation_date: 2011-08-16T02:38:01Z id: CL:0002673 name: tongue muscle cell def: "A skeletal muscle cell that is part of the tongue." [GOC:tfm, PMID:18816858] +subset: cellxgene_subset is_a: CL:0008002 ! skeletal muscle fiber intersection_of: CL:0008002 ! skeletal muscle fiber intersection_of: part_of UBERON:0000378 ! tongue muscle @@ -22551,6 +23016,7 @@ id: CL:0002677 name: naive regulatory T cell def: "A regulatory T cell that has not encountered antigen." [GOC:tfm] comment: This cell type has been described as CD45RA-negative, but this doesn't fit with our current definition of naive T cell. +subset: cellxgene_subset subset: human_reference_atlas synonym: "naive regulatory T lymphocyte" EXACT [] synonym: "naive regulatory T-cell" EXACT [] @@ -22566,6 +23032,7 @@ id: CL:0002678 name: memory regulatory T cell def: "A CD4-positive, CD25-positive alpha-beta regulatory T cell that has encountered antigen." [GOC:tfm, PMID:21739668] comment: Cell has been described as being CD45RA-positive in human, but this doesn't fit with our current definition memory T cell. +subset: cellxgene_subset is_a: CL:0000792 ! CD4-positive, CD25-positive, alpha-beta regulatory T cell is_a: CL:0000897 ! CD4-positive, alpha-beta memory T cell intersection_of: CL:0000792 ! CD4-positive, CD25-positive, alpha-beta regulatory T cell @@ -23164,6 +23631,7 @@ id: CL:0003050 name: S cone cell namespace: cell def: "A cone cell that detects short wavelength light. Exact peak of spectra detected differs between species. In humans, spectra peaks at 420-440 nm." [WikipediaVersioned:Cone_cell&oldid=1111888680] +subset: cellxgene_subset synonym: "S cone" EXACT [PMID:32555229] synonym: "S-(short-wavelength sensitive) cone" EXACT [PMID:31117170] synonym: "S-cone" EXACT [PMID:32555229] @@ -23428,6 +23896,7 @@ id: CL:0004219 name: A2 amacrine cell namespace: cell def: "A bistratifed retinal amacrine cell with a small dendritic field, dendrite stratification in S1-S2, and a second dendrite stratification in S5. This cell type releases the neurotransmitter glycine." [PMID:24246263, PMID:9620701] +subset: cellxgene_subset subset: human_reference_atlas is_a: CL:0004250 ! bistratified retinal amacrine cell is_a: CL:0004251 ! narrow field retinal amacrine cell @@ -23592,6 +24061,7 @@ id: CL:0004232 name: starburst amacrine cell namespace: cell def: "An amacrine cell with a flat dendritic arbor and a medium dendritic field. Starburst amacrine cells have post-synaptic terminals in S2. This cell type releases the neurotransmitters gamma-aminobutyric acid (GABA) and acetylcholine." [PMID:32032773, PMID:9620701] +subset: cellxgene_subset subset: human_reference_atlas is_a: CL:0000108 ! cholinergic neuron is_a: CL:4030027 ! GABAergic amacrine cell @@ -23872,6 +24342,7 @@ relationship: develops_from CL:0000333 ! migratory neural crest cell id: CL:0005006 name: ionocyte def: "Specialized epithelial cells involved in the maintenance of osmotic homeostasis. They are characterized by abundant mitochondria and ion transporters. In amniotes, they are present in the renal system. In freshwater fish, ionocytes in the skin and gills help maintain osmotic homeostasis by absorbing salt from the external environment." [PMID:17555741, PMID:19268451] +subset: cellxgene_subset subset: human_reference_atlas is_a: CL:0000066 ! epithelial cell relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens @@ -23901,6 +24372,7 @@ relationship: part_of UBERON:0000054 ! macula id: CL:0005009 name: renal principal cell def: "A cuboidal epithelial cell of the kidney which regulates sodium and potassium balance. The activity of sodium and potassium channels on the apical membrane of the cell is regulated by aldosterone and vasopressin. In mammals this cell type is located in the renal collecting duct system." [CL:CVS] +subset: cellxgene_subset is_a: CL:0000075 ! columnar/cuboidal epithelial cell is_a: CL:0002518 ! kidney epithelial cell @@ -23909,6 +24381,7 @@ id: CL:0005010 name: renal intercalated cell def: "A cuboidal epithelial cell of the kidney that regulates acid/base balance." [CL:CVS] comment: Intercalated cells are also called “mitochondria-rich cells”, reflecting the high levels of round mitochondria at their apical pole, or in their cytoplasm, a distribution that is quite different from that of other kidney tubule cells, which accumulated mitochondria around the basolateral membrane. These cells also have numerous irregular apical microvilli compared with the surrounding segment-specific cells. Intercalated cells lack a central cilium, at least in the cortex, which also differentiates them from the adjacent principal cells. {xref="PMID:25632105"} +subset: cellxgene_subset synonym: "intercalated cell" EXACT [] xref: FMA:86560 is_a: CL:0000075 ! columnar/cuboidal epithelial cell @@ -23920,6 +24393,7 @@ id: CL:0005011 name: renal alpha-intercalated cell def: "A cuboidal epithelial cell of the kidney which secretes acid and reabsorbs base to regulate acid/base balance." [CL:CVS] comment: Type A intercalated cells are the more abundant type of intercalated cell in the outer stripe of the outer medulla in most mammalian species. {xref="PMID:25632105"} +subset: cellxgene_subset synonym: "type A intercalated cell" EXACT [PMID:25632105] synonym: "type A-IC" EXACT [PMID:25632105] is_a: CL:0005010 ! renal intercalated cell @@ -23929,6 +24403,7 @@ relationship: capable_of GO:0046717 ! acid secretion id: CL:0005012 name: multi-ciliated epithelial cell def: "A ciliated epithelial cell with many cilia." [CL:CVS] +subset: cellxgene_subset synonym: "MCC" RELATED OMO:0003000 [] synonym: "multi-ciliated cell" BROAD [] synonym: "multiciliated cell" BROAD [] @@ -23985,6 +24460,7 @@ id: CL:0005019 name: pancreatic epsilon cell def: "Ghrelin secreting cells found in the endocrine pancreas." [PMID:14970313] comment: In mammals the endocrine pancreas is called the Islets of Langerhans. +subset: cellxgene_subset subset: human_reference_atlas synonym: "pancreatic E cell" EXACT [] is_a: CL:0005018 ! ghrelin secreting cell @@ -24010,6 +24486,7 @@ creation_date: 2012-01-12T04:44:34Z id: CL:0005021 name: mesenchymal lymphangioblast def: "Mesenchymal derived lymphatic progenitor cells that give rise to the superficial lymphatics." [PMID:15624319, PMID:18430230] +subset: cellxgene_subset is_a: CL:0000134 ! mesenchymal stem cell is_a: CL:0005020 ! lymphangioblast relationship: dc-contributor https://orcid.org/0000-0002-2244-7917 @@ -24019,6 +24496,7 @@ creation_date: 2012-01-12T05:01:22Z id: CL:0005022 name: vascular lymphangioblast def: "Lymphatic progenitor cells, derived from the veins, that give rise to lymphatic endothelial cells." [CL:CVS] +subset: cellxgene_subset synonym: "parachordal lymphangioblast" NARROW [] is_a: CL:0005020 {is_inferred="true"} ! lymphangioblast intersection_of: CL:0005020 ! lymphangioblast @@ -24055,6 +24533,7 @@ id: CL:0005025 name: visceromotor neuron def: "A motor neuron that synapses to parasympathetic neurons that innervate tear glands, sweat glands, and the smooth muscles and glands of the pulmonary, cardiovascular, and gastrointestinal systems." [ZFIN:CVS] comment: Note that these neurons do not synapse directly onto muscles +subset: cellxgene_subset synonym: "general visceral motor neuron" EXACT [] is_a: CL:0000100 ! motor neuron relationship: RO:0002120 CL:0011102 ! synapsed to parasympathetic neuron @@ -24063,6 +24542,7 @@ relationship: RO:0002120 CL:0011102 ! synapsed to parasympathetic neuron id: CL:0005026 name: hepatoblast def: "Multi fate stem cell that gives rise to both hepatocytes and cholangiocytes as descendants. The term often refers to fetal precursors of hepatocytes (differently from 'hepatic stem cell', usually applied to the self-renewing pool of hepatocyte precursors in the adult liver). Hepatoblasts may also be endogenous, as some stem cells found in the liver come from the bone marrow via blood circulation." [GOC:CVS, https://orcid.org/0000-0003-1940-6740, PMID:18356246, PMID:20483998, PMID:26798363] +subset: cellxgene_subset is_a: CL:0000048 ! multi fate stem cell property_value: seeAlso "https://github.com/obophenotype/cell-ontology/issues/800" xsd:string @@ -24169,6 +24649,7 @@ creation_date: 2012-06-27T10:44:01Z id: CL:0007010 name: preosteoblast def: "Skeletogenic cell that has the potential to transform into an osteoblast, and develops from neural crest or mesodermal cells." [GO_REF:0000034] +subset: cellxgene_subset synonym: "osteoprogenitor cell" EXACT [] is_a: CL:0000055 ! non-terminally differentiated cell is_a: CL:0001035 ! bone cell @@ -24184,6 +24665,7 @@ creation_date: 2012-06-27T10:57:21Z id: CL:0007011 name: enteric neuron def: "Neuron that is part of the enteric nervous system." [CL:MAH] +subset: cellxgene_subset is_a: CL:0000029 ! neural crest derived neuron is_a: CL:0000107 ! autonomic neuron intersection_of: CL:0000540 ! neuron @@ -24312,12 +24794,14 @@ is_a: CL:0000187 ! muscle cell id: CL:0008001 name: hematopoietic precursor cell def: "Any hematopoietic cell that is a precursor of some other hematopoietic cell type." [GOC:dos] +subset: cellxgene_subset is_a: CL:0000988 ! hematopoietic cell [Term] id: CL:0008002 name: skeletal muscle fiber def: "A transversely striated, synctial cell of skeletal muscle. It is formed when proliferating myoblasts exit the cell cycle, differentiate and fuse." [GOC:tfm, ISBN:0323052908] +subset: cellxgene_subset xref: MESH:D018485 is_a: CL:0000188 ! cell of skeletal muscle is_a: CL:0002372 ! myotube @@ -24405,6 +24889,7 @@ intersection_of: RO:0002120 CL:0008002 ! synapsed to skeletal muscle fiber id: CL:0008011 name: skeletal muscle satellite stem cell def: "A skeletal muscle satellite cell that divides by stem cell division. A proportion of this population undergoes symmetric stem cell division, producing two skeletal muscle satellite stem cells. The rest undergo asymmetric stem cell division - retaining their identity while budding off a daughter cell that differentiates into an adult skeletal muscle myoblast." [PMID:23303905] +subset: cellxgene_subset is_a: CL:0000035 ! single fate stem cell is_a: CL:0000594 ! skeletal muscle satellite cell intersection_of: CL:0000594 ! skeletal muscle satellite cell @@ -24441,6 +24926,7 @@ id: CL:0008015 name: inhibitory motor neuron def: "A motor neuron that is capable of directly inhibiting muscle contraction." [] comment: In vertebrates, all motor neurons are excitatory, but various types of inhibitory motor neurons exist in invertebrates. +subset: cellxgene_subset is_a: CL:0000100 ! motor neuron relationship: never_in_taxon NCBITaxon:7742 ! Vertebrata @@ -24460,8 +24946,8 @@ synonym: "myogenic precursor cell" BROAD [PMID:23303905] is_a: CL:0000188 ! cell of skeletal muscle is_a: CL:0000515 ! skeletal muscle myoblast intersection_of: CL:0000056 ! myoblast +intersection_of: develops_into CL:0008002 ! skeletal muscle fiber intersection_of: part_of UBERON:0001134 ! skeletal muscle tissue -intersection_of: RO:0002203 CL:0008002 ! develops into skeletal muscle fiber [Term] id: CL:0008018 @@ -24469,13 +24955,14 @@ name: somatic muscle myoblast def: "A myoblast that is commited to developing into a somatic muscle." [] is_a: CL:0000056 ! myoblast intersection_of: CL:0000056 ! myoblast -intersection_of: RO:0002203 CL:0008003 ! develops into somatic muscle myotube -relationship: RO:0002203 CL:0008003 ! develops into somatic muscle myotube +intersection_of: develops_into CL:0008003 ! somatic muscle myotube +relationship: develops_into CL:0008003 ! somatic muscle myotube [Term] id: CL:0008019 name: mesenchymal cell def: "A non-polarised cell precursor cell that is part of some mesenchyme, is associated with the cell matrix but is not connected to other cells and is capable of migration." [] +subset: cellxgene_subset subset: human_reference_atlas synonym: "mesenchyme cell" EXACT [] is_a: CL:0000219 ! motile cell @@ -24488,7 +24975,7 @@ id: CL:0008020 name: skeletal muscle satellite myogenic cell def: "A skeletal muscle satellite cell that undergoes symmetric division to produce two adult skeleltal muscle myoblasts." [GOC:dos, PMID:23303905] is_a: CL:0000594 ! skeletal muscle satellite cell -relationship: RO:0002203 CL:0008017 ! develops into adult skeletal muscle myoblast +relationship: develops_into CL:0008017 ! adult skeletal muscle myoblast [Term] id: CL:0008021 @@ -24519,6 +25006,7 @@ replaced_by: CL:0002548 id: CL:0008024 name: pancreatic endocrine cell def: "An endocrine cell that is part of the pancreas." [GOC:dos] +subset: cellxgene_subset subset: human_reference_atlas is_a: CL:0000083 ! epithelial cell of pancreas is_a: CL:0000164 ! enteroendocrine cell @@ -24567,16 +25055,18 @@ creation_date: 2017-07-09T19:12:36Z [Term] id: CL:0008029 name: obsolete inhibitory neuron -comment: See https://github.com/obophenotype/cell-ontology/issues/1540. Consider GABAergic neuron or inhibitory interneuron instead. Do note that not all GABAergic neurons are inhibitory (see PMID:12209121) and replacing inhibitory neuron with GABAergic neuron should be done with caution. +comment: Consider GABAergic neuron or inhibitory interneuron instead. Do note that not all GABAergic neurons are inhibitory (see PMID:12209121) and replacing inhibitory neuron with GABAergic neuron should be done with caution. relationship: dc-contributor https://orcid.org/0000-0002-7073-9172 +relationship: term_tracker_item https://github.com/obophenotype/cell-ontology/issues/1540 is_obsolete: true creation_date: 2017-07-12T11:10:52Z [Term] id: CL:0008030 name: obsolete excitatory neuron -comment: See https://github.com/obophenotype/cell-ontology/issues/1540. Consider using glutamatergic neuron instead. Do note that not all glutamatergic neurons are excitatory and replacing excitatory neuron with glutamatergic neuron should be done with caution. +comment: Consider using glutamatergic neuron instead. Do note that not all glutamatergic neurons are excitatory and replacing excitatory neuron with glutamatergic neuron should be done with caution. relationship: dc-contributor https://orcid.org/0000-0002-7073-9172 +relationship: term_tracker_item https://github.com/obophenotype/cell-ontology/issues/1540 is_obsolete: true creation_date: 2017-07-12T11:11:06Z @@ -24584,6 +25074,7 @@ creation_date: 2017-07-12T11:11:06Z id: CL:0008031 name: cortical interneuron def: "An interneuron that has its soma located in the cerebral cortex." [] +subset: cellxgene_subset synonym: "cerebral cortex interneuron" EXACT [] is_a: CL:0000402 ! CNS interneuron is_a: CL:0010012 ! cerebral cortex neuron @@ -24622,6 +25113,7 @@ id: CL:0008034 name: mural cell def: "Mural cells are pericytes and the vascular smooth muscle cells (vSMCs) of the microcirculation." [Wiki:Mural_cell&oldid=930603194] subset: added_for_HCA +subset: cellxgene_subset subset: human_reference_atlas is_a: CL:4033054 ! perivascular cell relationship: dc-contributor https://orcid.org/0000-0002-7073-9172 @@ -24644,6 +25136,7 @@ id: CL:0008036 name: extravillous trophoblast def: "A trophoblast cell that is not part of a placental villous." [PMID:31049600] subset: added_for_HCA +subset: cellxgene_subset subset: human_reference_atlas synonym: "EVT" EXACT [PMID:31049600] synonym: "extravillous cytotrophloblast" EXACT [] @@ -24757,6 +25250,7 @@ is_a: CL:0009004 ! retinal cell id: CL:0009002 name: inflammatory cell def: "Any cell participating in the inflammatory response to a foreign substance, e.g. neutrophil, macrophage." [] +subset: cellxgene_subset xref: GOC:pr xref: http://en.wikipedia.org/wiki/Inflammatory_response is_a: CL:0000000 ! cell @@ -24789,6 +25283,7 @@ relationship: part_of UBERON:0005388 ! photoreceptor array id: CL:0009005 name: salivary gland cell def: "Any cell in a salivary gland." [] +subset: cellxgene_subset xref: GOC:pr xref: http://en.wikipedia.org/wiki/Salivary_gland is_a: CL:0000000 ! cell @@ -24798,6 +25293,7 @@ relationship: part_of UBERON:0001044 ! saliva-secreting gland id: CL:0009006 name: enteroendocrine cell of small intestine def: "An enteroendocrine cell that is located in the small intestine." [http://orcid.org/0000-0003-3440-1876] +subset: cellxgene_subset subset: location_grouping synonym: "small intestine enteroendocrine cell" EXACT [] is_a: CL:1001516 ! intestinal enteroendocrine cell @@ -24836,6 +25332,7 @@ relationship: part_of UBERON:0011189 ! lamina propria of large intestine id: CL:0009009 name: paneth cell of colon def: "A paneth cell that is located in the epithelium of the colon." [http://orcid.org/0000-0003-4183-8865, PMID:31753849] +subset: cellxgene_subset subset: human_reference_atlas subset: location_grouping synonym: "paneth cell of epithelium of colon" EXACT [] @@ -24852,6 +25349,7 @@ relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens id: CL:0009010 name: transit amplifying cell def: "Transit-amplifying cells (TACs) are an undifferentiated population in transition between stem cells and differentiated cells." [http://orcid.org/0000-0003-4183-8865, PMID:24813615, PMID:28835754] +subset: cellxgene_subset synonym: "TAC" RELATED [] synonym: "TACs" RELATED [] synonym: "transient amplifying cell" EXACT [] @@ -24865,6 +25363,7 @@ relationship: develops_from CL:0000034 ! stem cell id: CL:0009011 name: transit amplifying cell of colon def: "A rapidly proliferating population of cells that differentiate from stem cells of the intestinal crypt of the colon. Stem cells located in the crypts of Lieberkühn give rise to proliferating progenitor or transit amplifying cells that differentiate into the four major epithelial cell types. These include columnar absorptive cells or enterocytes, mucous secreting goblet cells, enteroendocrine cells and paneth cells." [http://orcid.org/0000-0003-4183-8865, PMID:20801415] +subset: cellxgene_subset subset: human_reference_atlas subset: location_grouping synonym: "colon transit amplifying cell" EXACT [] @@ -24885,6 +25384,7 @@ relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens id: CL:0009012 name: transit amplifying cell of small intestine def: "A rapidly proliferating population of cells that differentiate from stem cells of the intestinal crypt of the small intestine. Stem cells located in the crypts of Lieberkühn give rise to proliferating progenitor or transit amplifying cells that differentiate into the four major epithelial cell types. These include columnar absorptive cells or enterocytes, mucous secreting goblet cells, enteroendocrine cells and paneth cells." [http://orcid.org/0000-0003-4183-8865, PMID:20801415] +subset: cellxgene_subset subset: location_grouping synonym: "small intestine transit amplifying cell" EXACT [] synonym: "transient amplifying cell of crypt of Lieberkuhn of small intestine" EXACT [] @@ -24938,6 +25438,7 @@ relationship: part_of UBERON:0001211 ! Peyer's patch id: CL:0009016 name: intestinal crypt stem cell of large intestine def: "An intestinal stem cell that is located in the large intestine crypt of Liberkuhn. These stem cells reside at the bottom of crypts in the large intestine and are highly proliferative. They either differentiate into transit amplifying cells or self-renew to form new stem cells." [https://orcid.org/0000-0003-4183-8865, PMID:20683682] +subset: cellxgene_subset subset: human_reference_atlas subset: location_grouping synonym: "crypt stem cell of large intestine" BROAD [] @@ -24954,6 +25455,7 @@ relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens id: CL:0009017 name: intestinal crypt stem cell of small intestine def: "An intestinal stem cell that is located in the small intestine crypt of Liberkuhn. These stem cells reside at the bottom of crypts in the small intestine and are highly proliferative. They either differentiate into transit amplifying cells or self-renew to form new stem cells." [https://orcid.org/0000-0003-4183-8865, PMID:20683682] +subset: cellxgene_subset subset: location_grouping synonym: "crypt stem cell of small intestine" BROAD [] synonym: "stem cell of small intestine crypt of Lieberkuhn" EXACT [] @@ -25021,6 +25523,7 @@ relationship: part_of UBERON:0011189 ! lamina propria of large intestine id: CL:0009022 name: stromal cell of lamina propria of small intestine def: "A stromal cell found in the lamina propria of the small intestine." [http://orcid.org/0000-0003-4183-8865] +subset: cellxgene_subset subset: location_grouping is_a: CL:0000499 ! stromal cell intersection_of: CL:0000499 ! stromal cell @@ -25247,6 +25750,7 @@ id: CL:0009038 name: colon macrophage def: "A macrophage that is located in the colon." [http://orcid.org/0000-0003-3440-1876] comment: This is a general grouping term created for use in the EMBL-EBI Single Cell Expression Atlas anatomograms. Please use a more specific cell type term for annotation if possible, given the information available to you. +subset: cellxgene_subset subset: location_grouping synonym: "macrophage of colon" EXACT [] is_a: CL:0000235 ! macrophage @@ -25259,6 +25763,7 @@ relationship: part_of UBERON:0001155 ! colon id: CL:0009039 name: colon goblet cell def: "A goblet cell that is located in the colon." [http://orcid.org/0000-0003-3440-1876] +subset: cellxgene_subset subset: location_grouping synonym: "goblet cell of colon" EXACT [] is_a: CL:1000320 ! large intestine goblet cell @@ -25283,6 +25788,7 @@ relationship: part_of UBERON:0007177 ! lamina propria of mucosa of colon id: CL:0009041 name: tuft cell of colon def: "A tuft cell that is a part of the colon." [http://orcid.org/0000-0003-3440-1876] +subset: cellxgene_subset subset: location_grouping synonym: "colon tuft cell" EXACT [] is_a: CL:0002203 ! brush cell of epithelium proper of large intestine @@ -25295,6 +25801,7 @@ relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 id: CL:0009042 name: enteroendocrine cell of colon def: "An enteroendocrine cell that is located in the colon." [http://orcid.org/0000-0003-3440-1876] +subset: cellxgene_subset subset: location_grouping synonym: "colon enteroendocrine cell" EXACT [] is_a: CL:1001516 ! intestinal enteroendocrine cell @@ -25307,6 +25814,7 @@ relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 id: CL:0009043 name: intestinal crypt stem cell of colon def: "An intestinal crypt stem cell that is located in the colon." [http://orcid.org/0000-0003-3440-1876] +subset: cellxgene_subset subset: location_grouping is_a: CL:0002250 ! intestinal crypt stem cell is_a: CL:0011108 ! colon epithelial cell @@ -25861,6 +26369,7 @@ property_value: dcterms-date "2022-02-18T10:12:57Z" xsd:dateTime id: CL:0009089 name: lung pericyte def: "A pericyte cell that is part of a lung." [https://orcid.org/0000-0003-3440-1876, https://orcid.org/0000-0003-4183-8865] +subset: cellxgene_subset subset: human_reference_atlas subset: location_grouping synonym: "lung pericyte cell" EXACT [] @@ -25899,6 +26408,7 @@ property_value: dcterms-date "2022-02-18T14:09:25Z" xsd:dateTime id: CL:0009092 name: endothelial cell of placenta def: "An endothelial cell that is part of a placenta." [https://orcid.org/0000-0003-3440-1876, https://orcid.org/0000-0003-4183-8865] +subset: cellxgene_subset subset: location_grouping synonym: "placental endothelial cell" EXACT [] xref: EFO:0010708 @@ -25941,6 +26451,7 @@ property_value: dcterms-date "2021-12-13T14:01:05Z" xsd:dateTime id: CL:0009095 name: endothelial cell of uterus def: "An endothelial cell that is part of a uterus." [https://orcid.org/0000-0003-3440-1876, https://orcid.org/0000-0003-4183-8865] +subset: cellxgene_subset subset: location_grouping synonym: "uterine endothelial cell" EXACT [] xref: EFO:0010711 @@ -26000,6 +26511,7 @@ property_value: dcterms-date "2022-02-21T15:43:16Z" xsd:dateTime id: CL:0009099 name: fibro/adipogenic progenitor cell def: "A progenitor cell that is a tissue-resident mesenchymal cell, important for skeletal muscle regeneration, and able to differentiate into both adipocytes or fibroblasts." [PMID:20081841, PMID:22045730, PMID:24605102] +subset: cellxgene_subset synonym: "fibro/adipogenic progenitor" EXACT [] is_a: CL:0008019 ! mesenchymal cell is_a: CL:0011026 ! progenitor cell @@ -26159,6 +26671,7 @@ property_value: dcterms-date "2022-03-23T15:13:30Z" xsd:dateTime id: CL:0009111 name: centrocyte def: "A germinal center B cell found in a lymph node germinal center light zone." [https://orcid.org/0000-0001-7655-4833, PMID:17067937] +subset: cellxgene_subset subset: human_reference_atlas synonym: "lymph node centrocyte" EXACT [] is_a: CL:0000844 ! germinal center B cell @@ -26171,6 +26684,7 @@ property_value: dcterms-date "2022-03-24T09:03:44Z" xsd:dateTime id: CL:0009112 name: centroblast def: "A germinal center B cell found in a lymph node germinal center dark zone." [https://orcid.org/0000-0001-7655-4833, PMID:17067937] +subset: cellxgene_subset subset: human_reference_atlas synonym: "lymph node centroblast" EXACT [] is_a: CL:0000844 ! germinal center B cell @@ -26183,6 +26697,7 @@ property_value: dcterms-date "2022-03-24T09:12:41Z" xsd:dateTime id: CL:0009113 name: T follicular regulatory cell def: "A regulatory T cell present in the B cell follicles and germinal centers of lymphoid tissues. In humans, it is CXCR5+." [https://orcid.org/0000-0001-7655-4833, PMID:15578096, PMID:26501424, PMID:29769249] +subset: cellxgene_subset subset: human_reference_atlas synonym: "follicular regulatory T cell" EXACT [] is_a: CL:0000815 ! regulatory T cell @@ -26221,6 +26736,7 @@ property_value: seeAlso "https://github.com/obophenotype/cell-ontology/issues/14 id: CL:0009116 name: progenitor cell of mammary luminal epithelium def: "A progenitor cell with the potential to differentiate into luminal epithelial cells of mammary glands. In mouse, CD61 and c-kit were found to be coexpressed by the majority of, but not all, committed luminal progenitor cells." [https://orcid.org/0000-0003-4412-7970, PMID:19063729, PMID:20346151, PMID:21930782] +subset: cellxgene_subset synonym: "luminal progenitor cell" BROAD [] synonym: "progenitor cell of luminal mammary epithelium" EXACT [] is_a: CL:0011026 ! progenitor cell @@ -26261,6 +26777,7 @@ id: CL:0010003 name: epithelial cell of alveolus of lung def: "An epithelial cell that is part_of a alveolus of lung." [] comment: May be merged with pneumocyte in future +subset: cellxgene_subset synonym: "alveolus of lung epithelial cell" EXACT [] xref: MESH:D056809 is_a: CL:0000082 ! epithelial cell of lung @@ -26309,6 +26826,7 @@ relationship: part_of UBERON:0004146 ! His-Purkinje system [Term] id: CL:0010008 name: cardiac endothelial cell +subset: cellxgene_subset subset: human_reference_atlas is_a: CL:0000115 ! endothelial cell is_a: CL:0002494 ! cardiocyte @@ -26338,6 +26856,7 @@ intersection_of: RO:0002100 UBERON:0002037 ! has soma location cerebellum id: CL:0010011 name: cerebral cortex GABAergic interneuron def: "A GABAergic interneuron whose soma is located in the cerebral cortex." [GOC:dos] +subset: cellxgene_subset is_a: CL:0008031 ! cortical interneuron is_a: CL:0011005 ! GABAergic interneuron intersection_of: CL:0011005 ! GABAergic interneuron @@ -26348,6 +26867,7 @@ id: CL:0010012 name: cerebral cortex neuron alt_id: CL:0002609 def: "A CNS neuron of the cerebral cortex." [GOC:tfm] +subset: cellxgene_subset subset: human_reference_atlas synonym: "cortical neuron" EXACT [] synonym: "neuron of cerebral cortex" EXACT [] @@ -26409,14 +26929,15 @@ name: cardiac myoblast xref: MESH:D032386 is_a: CL:0000056 ! myoblast intersection_of: CL:0000056 ! myoblast -intersection_of: RO:0002203 CL:0000746 ! develops into cardiac muscle cell -relationship: RO:0002203 CL:0000746 ! develops into cardiac muscle cell +intersection_of: develops_into CL:0000746 ! cardiac muscle cell +relationship: develops_into CL:0000746 ! cardiac muscle cell [Term] id: CL:0010022 name: cardiac neuron def: "A neuron that has its soma in the heart." [PMID:12486170, PMID:29265764] comment: This term is used in 3 GO terms that were created as part of the heart development focus project. +subset: cellxgene_subset is_a: CL:0000540 ! neuron intersection_of: CL:0000540 ! neuron intersection_of: RO:0002100 UBERON:0000948 ! has soma location heart @@ -26465,6 +26986,7 @@ relationship: RO:0002100 UBERON:0001898 ! has soma location hypothalamus id: CL:0011004 name: lens fiber cell def: "A vetebrate lens cell that is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye." [GO:0070307, GOC:nv] +subset: cellxgene_subset subset: human_reference_atlas synonym: "lens fibre cell" EXACT [] is_a: CL:0002222 ! vertebrate lens cell @@ -26530,6 +27052,7 @@ is_a: CL:0000222 ! mesodermal cell id: CL:0011012 name: neural crest cell def: "A cell of the neural crest. Neural crest cells are multipotent. Premigratory neural crest cells are found at the neural plate boarder, some of which will undergo ectomesynchymal transition and delamination to form migratory neural crest cells." [https://orcid.org/0000-0001-5208-3432, https://orcid.org/0000-0002-9900-7880] +subset: cellxgene_subset is_a: CL:0000048 ! multi fate stem cell is_a: CL:0002321 ! embryonic cell (metazoa) @@ -26589,6 +27112,7 @@ relationship: RO:0002104 PR:000001869 ! has plasma membrane part interleukin-7 r id: CL:0011019 name: mesothelial cell of epicardium def: "A mesothelial cell that is part of the epicardium." [] +subset: cellxgene_subset is_a: CL:0000077 ! mesothelial cell is_a: CL:0002494 ! cardiocyte intersection_of: CL:0000077 ! mesothelial cell @@ -26600,6 +27124,7 @@ relationship: part_of UBERON:0002348 ! epicardium id: CL:0011020 name: neural progenitor cell def: "An undifferentiated cell that originates from a neural stem cell and has the capacity to generate multiple types of lineage-restricted progenitors but not to self-renew." [PMID:30574073] +subset: cellxgene_subset is_a: CL:0000055 ! non-terminally differentiated cell relationship: dc-contributor https://orcid.org/0000-0001-5208-3432 @@ -26642,6 +27167,7 @@ relationship: RO:0002104 PR:000001380 ! has plasma membrane part interleukin-2 r id: CL:0011024 name: double negative T regulatory cell def: "A double negative thymocyte that is CD3-positive, CD4-negative, CD8-negative, that that are present in the periphery in very low numbers and predominantly produce INF-gamma, TNF-alpha, and a low amount of TGF-beta, but not IL-2, IL-4, IL-10 or IL-13 upon activation." [PMID:16285891] +subset: cellxgene_subset synonym: "CD4-negative, CD8-negative, alpha-beta regulatory T cells" EXACT [] synonym: "DN Treg" EXACT [] synonym: "double-negative alpha-beta regulatory T cell" EXACT [] @@ -26654,6 +27180,7 @@ relationship: dc-contributor https://orcid.org/0000-0001-5208-3432 [Term] id: CL:0011025 name: exhausted T cell +subset: cellxgene_subset synonym: "An effector T cell that displays impaired effector functions (e.g., rapid production of effector cytokines, cytotoxicity) and has limited proliferative potential." EXACT [PMID:26544946] synonym: "Tex cell" EXACT [] is_a: CL:0000911 ! effector T cell @@ -26663,6 +27190,7 @@ relationship: dc-contributor https://orcid.org/0000-0001-5208-3432 id: CL:0011026 name: progenitor cell def: "A precursor cell that has a tendency to differentiate into a specific type of cell. They are descendants of stem cells, only they are more constrained in their differentiation potential or capacity for self-renewal, and are often more limited in both senses." [https://doi.org/10.1016/B978-0-12-409503-8.00002-0, ISBN:978-1-62808-994-3] +subset: cellxgene_subset is_a: CL:0011115 ! precursor cell intersection_of: CL:0011115 ! precursor cell intersection_of: develops_from CL:0000034 ! stem cell @@ -26673,6 +27201,7 @@ relationship: develops_from CL:0000034 ! stem cell id: CL:0011027 name: skeletal muscle fibroblast def: "Any fibroblast that is part of skeletal muscle tissue." [https://orcid.org/0000-0001-6164-0667, PMID:28369879] +subset: cellxgene_subset synonym: "skeleton muscle fibroblast" EXACT [] is_a: CL:0000188 ! cell of skeletal muscle is_a: CL:1001609 ! muscle fibroblast @@ -26744,6 +27273,7 @@ is_a: CL:0000540 ! neuron id: CL:0011101 name: chorionic trophoblast cell def: "Cells of the uterine chorion that acquire specialized structural and/or functional features that characterize chorionic trophoblasts. These cells will migrate towards the spongiotrophoblast layer and give rise to syncytiotrophoblasts of the labyrinthine layer." [GOC:NV] +subset: cellxgene_subset is_a: CL:0000351 ! trophoblast cell intersection_of: CL:0000351 ! trophoblast cell intersection_of: part_of UBERON:0003124 ! chorion membrane @@ -26759,6 +27289,7 @@ is_a: CL:0000107 ! autonomic neuron id: CL:0011103 name: sympathetic neuron def: "Sympathetic neurons are part of the sympathetic nervous system and are primarily adrenergic producing the neurotransmitter noradrenalin along with other neuropeptides." [GOC:NV, isbn:0080923437] +subset: cellxgene_subset subset: human_reference_atlas is_a: CL:0000107 ! autonomic neuron relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens @@ -26807,6 +27338,7 @@ replaced_by: CL:0000636 id: CL:0011108 name: colon epithelial cell def: "Epithelial cell that is part of the colon epithelium." [GOC:NV] +subset: cellxgene_subset synonym: "colonic epithelial cell" EXACT [] is_a: CL:0002253 ! epithelial cell of large intestine intersection_of: CL:0000066 ! epithelial cell @@ -26873,6 +27405,7 @@ id: CL:0011115 name: precursor cell def: "A cell that, by division or terminal differentiation, can give rise to other cell types." [GOC:dos] comment: Work is needed on GO 'cell differentiation' before it is clear whether the equivalent class definition 'native cell' that capable_of some 'cell differentiation' works. Also, may want to consider merging this with non-terminally differentiated cell. +subset: cellxgene_subset is_a: CL:0000000 ! cell intersection_of: CL:0000000 ! cell intersection_of: capable_of GO:0030154 ! cell differentiation @@ -26909,6 +27442,7 @@ relationship: RO:0002100 UBERON:0001890 ! has soma location forebrain [Term] id: CL:0013000 name: forebrain radial glial cell +subset: cellxgene_subset is_a: CL:0000681 ! radial glial cell intersection_of: CL:0000681 ! radial glial cell intersection_of: part_of UBERON:0001890 ! forebrain @@ -26926,6 +27460,7 @@ is_a: CL:0000100 ! motor neuron id: CL:0017000 name: pulmonary ionocyte def: "An ionocyte that is part of the lung epithelium. The cells from this type are major sources of the CFTR protein in human and mice." [PMID:30069044, PMID:30069046] +subset: cellxgene_subset subset: human_reference_atlas is_a: CL:0000082 ! epithelial cell of lung is_a: CL:0005006 ! ionocyte @@ -27058,7 +27593,7 @@ name: obsolete lobed nucleus def: "Nucleus with two or more lobes connected by a thin filament that contains no internal chromatin." [GOC:tfm] comment: Obsoleted because duplicate with GO term. relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 -property_value: seeAlso "https://github.com/obophenotype/cell-ontology/issues/734" xsd:string +relationship: term_tracker_item https://github.com/obophenotype/cell-ontology/issues/734 is_obsolete: true replaced_by: GO:0098537 creation_date: 2009-12-22T03:54:43Z @@ -27099,13 +27634,13 @@ creation_date: 2009-12-28T04:25:23Z [Term] id: CL:0017505 -name: increased nucleus size -def: "A nucleus size quality which is relatively high compared to the amount of cytoplasm present in the same cell." [GOC:tfm] -is_a: GO:0005634 ! nucleus -intersection_of: GO:0005634 ! nucleus -intersection_of: bearer_of PATO:0000586 ! increased size -relationship: bearer_of PATO:0000586 ! increased size +name: obsolete increased nucleus size +def: "OBSOLETE. A nucleus size quality which is relatively high compared to the amount of cytoplasm present in the same cell." [GOC:tfm] +comment: This class was a phenotype, not a cell type. relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 +relationship: term_tracker_item https://github.com/obophenotype/cell-ontology/issues/2251 +is_obsolete: true +replaced_by: PATO:0040072 creation_date: 2009-12-23T10:53:24Z [Term] @@ -27148,6 +27683,7 @@ id: CL:0019001 name: tracheobronchial serous cell def: "Any serous secreting cell that is part of the tracheobronchial epithelium." [] subset: added_for_HCA +subset: cellxgene_subset synonym: "serous cell of tracheobronchial tree" EXACT [] is_a: CL:0000313 ! serous secreting cell intersection_of: CL:0000313 ! serous secreting cell @@ -27176,6 +27712,7 @@ id: CL:0019003 name: tracheobronchial goblet cell def: "Any goblet cell that is part of the tracheobronchial epithelium." [] subset: added_for_HCA +subset: cellxgene_subset subset: human_reference_atlas synonym: "goblet cell of tracheobronchial tree" EXACT [] is_a: CL:0002202 ! epithelial cell of tracheobronchial tree @@ -27233,6 +27770,7 @@ property_value: dcterms-date "2020-07-21T12:42:48Z" xsd:dateTime id: CL:0019019 name: tracheobronchial smooth muscle cell def: "A smooth muscle cell that is part of the tracheobronchial tree." [PMID:10853867] +subset: cellxgene_subset subset: human_reference_atlas synonym: "smooth muscle cell of tracheobronchial tree" EXACT [] is_a: CL:0000192 ! smooth muscle cell @@ -27259,6 +27797,7 @@ property_value: dcterms-date "2020-09-03T12:24:24Z" xsd:dateTime id: CL:0019021 name: endothelial cell of periportal hepatic sinusoid def: "An endothelial cell found in the periportal region hepatic sinusoid, near the portal triad. The fenestrae of these cells are larger but fewer in number compared with those of endothelial cells near the centrilobular region of the hepatic sinusoid." [PMID:27423426] +subset: cellxgene_subset synonym: "periportal hepatic sinusoidal endothelial cell" EXACT [PMID:30348985] synonym: "periportal LSEC" EXACT [PMID:28287163] xref: EFO:0010705 @@ -27273,6 +27812,7 @@ property_value: dcterms-date "2020-09-09T13:56:47Z" xsd:dateTime id: CL:0019022 name: endothelial cell of pericentral hepatic sinusoid def: "An endothelial cell found in the centrilobular region hepatic sinusoid, near the central vein. The fenestrae of these cells are smaller but more numerous compared with those of endothelial cells near the periportal region of the hepatic sinusoid." [PMID:27423426] +subset: cellxgene_subset synonym: "central venous hepatic sinusoidal endothelial cell" EXACT [PMID:30348985] synonym: "pericentral LSEC" EXACT [PMID:28287163] xref: EFO:0010706 @@ -27287,6 +27827,7 @@ property_value: dcterms-date "2020-09-10T12:38:29Z" xsd:dateTime id: CL:0019026 name: periportal region hepatocyte def: "Any hepatocyte that is part of the liver lobule periportal region. These cells are primarily involved in oxidative energy metabolism." [PMID:29763190] +subset: cellxgene_subset subset: human_reference_atlas synonym: "periportal hepatocyte" EXACT [PMID:29763190] is_a: CL:0000182 ! hepatocyte @@ -27301,6 +27842,7 @@ property_value: dcterms-date "2020-10-12T10:29:31Z" xsd:dateTime id: CL:0019028 name: midzonal region hepatocyte def: "Any hepatocyte that is part of the liver lobule midzonal region. These cells have mixed functionality in comparison with those in the other two regions of the liver lobule." [PMID:29763190] +subset: cellxgene_subset subset: human_reference_atlas synonym: "midzonal hepatocyte" EXACT [PMID:29763190] is_a: CL:0000182 ! hepatocyte @@ -27315,6 +27857,7 @@ property_value: dcterms-date "2020-10-12T10:57:40Z" xsd:dateTime id: CL:0019029 name: centrilobular region hepatocyte def: "Any hepatocyte that is part of the liver lobule centrilobular region. These cells are the primary location for the biotransformation of drugs." [PMID:29763190] +subset: cellxgene_subset subset: human_reference_atlas synonym: "centrilobular hepatocyte" EXACT [PMID:29763190] is_a: CL:0000182 ! hepatocyte @@ -27329,6 +27872,7 @@ property_value: dcterms-date "2020-10-12T11:03:51Z" xsd:dateTime id: CL:0019031 name: intestine goblet cell def: "Goblet cells reside throughout the length of the small and large intestine and are responsible for the production and maintenance of the protective mucus blanket by synthesizing and secreting high-molecular-weight glycoproteins known as mucins. Human intestinal goblet cells secrete the MUC2 mucin, as well as a number of typical mucus components: CLCA1, FCGBP, AGR2, ZG16, and TFF3." [PMID:1996606, PMID:24942678] +subset: cellxgene_subset synonym: "intestinal goblet cell" EXACT [PMID:1996606] is_a: CL:0000160 ! goblet cell is_a: CL:0002563 ! intestinal epithelial cell @@ -27341,6 +27885,7 @@ property_value: dcterms-date "2020-10-14T14:59:07Z" xsd:dateTime id: CL:0019032 name: intestinal tuft cell def: "Any brush cell that is part of the intestinal epithelium." [PMID:22527717] +subset: cellxgene_subset subset: human_reference_atlas synonym: "intestinal brush cell" EXACT [PMID:22527717] is_a: CL:0002204 ! brush cell @@ -27440,6 +27985,7 @@ relationship: part_of UBERON:0005146 ! metanephric nephron tubule [Term] id: CL:1000143 name: lung goblet cell +subset: cellxgene_subset is_a: CL:0000082 ! epithelial cell of lung is_a: CL:0002370 ! respiratory goblet cell is_a: CL:1000272 ! lung secretory cell @@ -27450,6 +27996,7 @@ intersection_of: part_of UBERON:0002048 ! lung id: CL:1000147 name: cardiac valve cell def: "A cell that is part of a cardiac valve." [PMID:25311230] +subset: cellxgene_subset synonym: "heart valve cell" EXACT [PMID:30796046] is_a: CL:0002494 ! cardiocyte intersection_of: CL:0000000 ! cell @@ -27505,6 +28052,7 @@ intersection_of: part_of UBERON:0000945 ! stomach id: CL:1000223 name: lung neuroendocrine cell def: "A neuroendocrine cell that is part of respiratory epithelium of the lung and is involved in the sensory detection of environmental stimuli, including hypoxia, nicotine and air pressure. Ultrastructurally, this cell type is characterized by the presence of cytoplasmic dense core granules, which are considered the storage sites of amine and peptide hormones. Lung neuroendocrine cells are innervated and appear as solitary cells or as clustered masses, localized at airway bifurcation sites, called neuroepithelial bodies that can release serotonin in response to hypoxia and interact with sensory nerve terminals. Lung neuroendocrine cells also function as reserve stem cells that repair the surrounding epithelium after injury." [doi:10.3109/01902148209069653, doi:10.7554/eLife.78216, PMID:33355253] +subset: cellxgene_subset subset: human_reference_atlas synonym: "PNEC" RELATED OMO:0003000 [PMID:33355253] synonym: "pulmonary neuroendocrine cell" EXACT [PMID:33355253] @@ -27548,6 +28096,7 @@ relationship: RO:0002100 UBERON:2001314 ! has soma location posterior lateral li [Term] id: CL:1000271 name: lung ciliated cell +subset: cellxgene_subset subset: human_reference_atlas is_a: CL:4030034 ! respiratory ciliated cell intersection_of: CL:0000064 ! ciliated cell @@ -27558,6 +28107,7 @@ relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: CL:1000272 name: lung secretory cell +subset: cellxgene_subset is_a: CL:0000151 ! secretory cell intersection_of: CL:0000151 ! secretory cell intersection_of: part_of UBERON:0002048 ! lung @@ -27573,6 +28123,7 @@ is_a: CL:0000349 ! extraembryonic cell id: CL:1000275 name: smooth muscle cell of small intestine def: "A smooth muscle cell that is part of the small intestine." [GOC:tfm] +subset: cellxgene_subset synonym: "non-striated muscle fiber of small intestine" EXACT [FMA:15050] xref: FMA:15050 is_a: CL:0002504 {is_inferred="true"} ! enteric smooth muscle cell @@ -27606,6 +28157,7 @@ relationship: part_of UBERON:0002115 ! jejunum id: CL:1000278 name: smooth muscle fiber of ileum def: "A smooth muscle cell that is part of the ileum." [GOC:tfm] +subset: cellxgene_subset synonym: "non-striated muscle fiber of ileum" EXACT [FMA:15066] xref: FMA:15066 is_a: CL:1000275 {is_inferred="true"} ! smooth muscle cell of small intestine @@ -27617,6 +28169,7 @@ relationship: part_of UBERON:0002116 ! ileum id: CL:1000279 name: smooth muscle cell of large intestine def: "A smooth muscle cell that is part of the large intestine." [GOC:tfm] +subset: cellxgene_subset subset: human_reference_atlas synonym: "non-striated muscle fiber of large intestine" EXACT [FMA:15653] xref: FMA:15653 @@ -27744,6 +28297,7 @@ is_a: CL:0002096 ! internodal tract myocyte id: CL:1000296 name: epithelial cell of urethra def: "An epithelial cell that is part of the urethra." [GOC:tfm] +subset: cellxgene_subset xref: FMA:256165 is_a: CL:0000066 ! epithelial cell is_a: CL:1001320 ! urethra cell @@ -27766,6 +28320,7 @@ relationship: part_of UBERON:0002363 ! dura mater id: CL:1000299 name: fibroblast of connective tissue of prostate def: "A fibroblast that is part of the connective tissue of prostate." [GOC:tfm] +subset: cellxgene_subset subset: human_reference_atlas xref: FMA:261271 is_a: CL:0000057 ! fibroblast @@ -27814,6 +28369,7 @@ relationship: part_of UBERON:0006815 ! areolar connective tissue id: CL:1000304 name: fibroblast of connective tissue of nonglandular part of prostate def: "A fibroblast that is part of the connective tissue of nonglandular part of prostate." [GOC:tfm] +subset: cellxgene_subset xref: FMA:261281 is_a: CL:0000057 ! fibroblast relationship: part_of UBERON:0002367 ! prostate gland @@ -27822,6 +28378,7 @@ relationship: part_of UBERON:0002367 ! prostate gland id: CL:1000305 name: fibroblast of connective tissue of glandular part of prostate def: "A fibroblast that is part of the connective tissue of glandular part of prostate." [GOC:tfm] +subset: cellxgene_subset xref: FMA:261283 is_a: CL:0000057 ! fibroblast relationship: part_of UBERON:0002367 ! prostate gland @@ -27864,6 +28421,7 @@ relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens id: CL:1000309 name: epicardial adipocyte def: "An adipocyte that is part of the epicardial fat." [GOC:tfm] +subset: cellxgene_subset subset: human_reference_atlas synonym: "adipocyte of epicardial fat" EXACT [FMA:261293] synonym: "epicardial fat cell" EXACT [FMA:261293] @@ -27889,6 +28447,7 @@ relationship: part_of UBERON:0002080 ! heart right ventricle id: CL:1000311 name: adipocyte of epicardial fat of left ventricle def: "An adipocyte that is part of the epicardial fat of left ventricle." [GOC:tfm] +subset: cellxgene_subset synonym: "epicardial adipocyte of left ventricle" EXACT [FMA:261300] synonym: "epicardial fat cell of left ventricle" EXACT [FMA:261300] xref: FMA:261300 @@ -27901,6 +28460,7 @@ relationship: part_of UBERON:0002084 ! heart left ventricle id: CL:1000312 name: bronchial goblet cell def: "A goblet cell that is part of the epithelium of bronchus." [GOC:tfm] +subset: cellxgene_subset synonym: "goblet cell of epithelium of bronchus" EXACT [FMA:263032] xref: FMA:263032 is_a: CL:0002328 ! bronchial epithelial cell @@ -27980,6 +28540,7 @@ is_obsolete: true id: CL:1000320 name: large intestine goblet cell def: "A goblet cell that is part of the epithelium of large intestine." [GOC:tfm] +subset: cellxgene_subset synonym: "goblet cell of epithelium of large intestine" EXACT [] xref: FMA:263054 is_a: CL:0002658 ! glandular cell of the large intestine @@ -28052,6 +28613,7 @@ relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens id: CL:1000326 name: ileal goblet cell def: "A goblet cell that is part of the epithelium proper of ileum." [GOC:tfm] +subset: cellxgene_subset synonym: "goblet cell of epithelium proper of ileum" EXACT [] xref: FMA:263067 is_a: CL:1000317 ! intestinal villus goblet cell @@ -28080,6 +28642,7 @@ is_obsolete: true id: CL:1000329 name: tracheal goblet cell def: "A goblet cell that is part of the epithelium of trachea." [GOC:tfm] +subset: cellxgene_subset subset: human_reference_atlas synonym: "goblet cell of epithelium of trachea" EXACT [FMA:263075] xref: FMA:263075 @@ -28094,6 +28657,7 @@ relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens id: CL:1000330 name: serous cell of epithelium of trachea def: "A serous secreting cell that is part of the epithelium of trachea." [GOC:tfm] +subset: cellxgene_subset subset: human_reference_atlas xref: FMA:263078 is_a: CL:0019001 ! tracheobronchial serous cell @@ -28106,6 +28670,7 @@ relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens id: CL:1000331 name: serous cell of epithelium of bronchus def: "A serous secreting cell that is part of the epithelium of bronchus." [GOC:tfm] +subset: cellxgene_subset subset: human_reference_atlas xref: FMA:263080 is_a: CL:0019001 ! tracheobronchial serous cell @@ -28140,6 +28705,7 @@ relationship: part_of UBERON:8600001 ! epithelium of lobular bronchiole id: CL:1000334 name: enterocyte of epithelium of small intestine def: "An enterocyte that is part of the epithelium of small intestine." [GOC:tfm] +subset: cellxgene_subset xref: FMA:263086 is_a: CL:0000584 {is_inferred="true"} ! enterocyte is_a: CL:0002254 ! epithelial cell of small intestine @@ -28202,6 +28768,7 @@ is_a: CL:1000339 ! enterocyte of epithelium proper of small intestine id: CL:1000342 name: enterocyte of epithelium proper of ileum def: "An enterocyte that is part of the epithelium proper of ileum." [GOC:tfm] +subset: cellxgene_subset xref: FMA:263102 is_a: CL:1000339 ! enterocyte of epithelium proper of small intestine @@ -28209,6 +28776,7 @@ is_a: CL:1000339 ! enterocyte of epithelium proper of small intestine id: CL:1000343 name: paneth cell of epithelium of small intestine def: "A paneth cell that is part of the epithelium of small intestine." [GOC:tfm] +subset: cellxgene_subset xref: FMA:263104 is_a: CL:0000510 {is_inferred="true"} ! paneth cell is_a: CL:1001598 ! small intestine glandular cell @@ -28245,6 +28813,7 @@ is_a: CL:0002071 ! enterocyte of epithelium of large intestine id: CL:1000347 name: enterocyte of colon def: "A columnar cell of the colon that is part of the colonic epithelium." [GOC:tfm] +subset: cellxgene_subset synonym: "vacuolar absorptive cell of epithelium of colon" NARROW [] xref: FMA:263114 is_a: CL:0002071 {is_inferred="true"} ! enterocyte of epithelium of large intestine @@ -28256,6 +28825,7 @@ intersection_of: part_of UBERON:0000397 ! colonic epithelium id: CL:1000348 name: basal cell of epithelium of trachea def: "A basal cell that is part of the epithelium of trachea." [GOC:tfm] +subset: cellxgene_subset subset: human_reference_atlas xref: FMA:263118 is_a: CL:0000307 ! tracheal epithelial cell @@ -28326,6 +28896,7 @@ relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens id: CL:1000353 name: microfold cell of epithelium of small intestine def: "A M cell that is part of the epithelium of small intestine." [GOC:tfm] +subset: cellxgene_subset xref: FMA:263128 is_a: CL:0000682 {is_inferred="true"} ! M cell of gut is_a: CL:0002254 ! epithelial cell of small intestine @@ -28663,6 +29234,7 @@ relationship: part_of UBERON:0009967 ! spleen venous sinus id: CL:1000398 name: endothelial cell of hepatic sinusoid def: "An endothelial cell that is part of the hepatic sinusoid. These cells possess flattened areas containing perforations about 0.1 micrometers in diameter, known as fenestrae. The fenestrae are arranged in groups known as sieve plates." [GOC:tfm, PMID:3926620] +subset: cellxgene_subset subset: human_reference_atlas synonym: "endotheliocyte of hepatic sinusoid" EXACT [FMA:62911] synonym: "liver sinusoidal endothelial cell" EXACT [PMID:30348985] @@ -28749,6 +29321,7 @@ id: CL:1000413 name: endothelial cell of artery alt_id: CL:0002542 def: "A blood vessel endothelial cell that is part of an arterial endothelium." [GOC:tfm] +subset: cellxgene_subset subset: human_reference_atlas synonym: "arterial endothelial cell" EXACT [] xref: BTO:0004758 @@ -28764,6 +29337,7 @@ relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens id: CL:1000414 name: endothelial cell of venule def: "An endothelial cell that is part of the venule." [GOC:tfm] +subset: cellxgene_subset subset: human_reference_atlas xref: FMA:67762 is_a: CL:0002139 {is_inferred="true"} ! endothelial cell of vascular tree @@ -28881,6 +29455,7 @@ intersection_of: part_of UBERON:0001235 ! adrenal cortex id: CL:1000428 name: stem cell of epidermis def: "A somatic stem cell that is part of the epidermis." [GOC:tfm] +subset: cellxgene_subset synonym: "epidermal stem cell" EXACT [FMA:70541] xref: FMA:70541 is_a: CL:0000723 {is_inferred="true"} ! somatic stem cell @@ -28892,6 +29467,7 @@ relationship: part_of UBERON:0001003 ! skin epidermis id: CL:1000432 name: conjunctival epithelial cell def: "An epithelial cell that is part of the conjunctiva." [GOC:tfm] +subset: cellxgene_subset subset: eye_upper_slim synonym: "epithelial cell of conjunctiva" EXACT [FMA:70552] xref: FMA:70552 @@ -28935,6 +29511,7 @@ relationship: part_of UBERON:0001850 ! lacrimal drainage system id: CL:1000436 name: epithelial cell of lacrimal sac def: "An epithelial cell that is part of the lacrimal sac." [GOC:tfm] +subset: cellxgene_subset xref: FMA:70560 is_a: CL:1000437 ! epithelial cell of nasolacrimal duct intersection_of: CL:0000066 ! epithelial cell @@ -28977,6 +29554,7 @@ is_a: CL:1001428 ! bladder urothelial cell id: CL:1000443 name: ciliary muscle cell def: "A smooth muscle cell that is part of the ciliary body." [GOC:tfm] +subset: cellxgene_subset subset: eye_upper_slim synonym: "smooth muscle cell of ciliary body" EXACT [FMA:70610] xref: FMA:70610 @@ -29009,6 +29587,7 @@ relationship: part_of UBERON:0001608 ! dilatator pupillae id: CL:1000447 name: epithelial cell of stratum germinativum of esophagus def: "A basal cell that is part of the epithelium of esophagus." [GOC:tfm] +subset: cellxgene_subset synonym: "basal cell of esophageal epithelium" EXACT [FMA:70731] xref: FMA:70731 is_a: CL:0000646 {is_inferred="true"} ! basal cell @@ -29020,6 +29599,7 @@ relationship: part_of UBERON:0001976 ! epithelium of esophagus id: CL:1000448 name: epithelial cell of sweat gland def: "An epithelial cell that is part of the sweat gland." [GOC:tfm] +subset: cellxgene_subset xref: FMA:70952 is_a: CL:0000362 ! epidermal cell is_a: CL:0002308 ! epithelial cell of skin gland @@ -29031,6 +29611,7 @@ relationship: part_of UBERON:0001820 ! sweat gland id: CL:1000449 name: epithelial cell of nephron def: "An epithelial cell that is part of the nephron." [GOC:tfm] +subset: cellxgene_subset xref: FMA:70965 is_a: CL:0002518 ! kidney epithelial cell intersection_of: CL:0000066 ! epithelial cell @@ -29041,6 +29622,7 @@ relationship: part_of UBERON:0001285 ! nephron id: CL:1000450 name: epithelial cell of glomerular capsule def: "An epithelial cell that is part of the glomerular capsule." [GOC:tfm] +subset: cellxgene_subset subset: kidney_upper_slim synonym: "Bowmans capsule epithelial cell" EXACT [] synonym: "epithelial cell of Bowman's capsule" EXACT [FMA:70966] @@ -29062,6 +29644,7 @@ id: CL:1000452 name: parietal epithelial cell alt_id: CL:1000897 def: "An epithelial cell that is part of the glomerular parietal epithelium." [GOC:tfm] +subset: cellxgene_subset subset: human_reference_atlas synonym: "epithelial cell of parietal layer of glomerular capsule" EXACT [FMA:70968] xref: FMA:70968 @@ -29086,6 +29669,7 @@ relationship: part_of UBERON:0004136 ! intermediate tubule id: CL:1000454 name: kidney collecting duct epithelial cell def: "An epithelial cell that is part of the collecting duct of renal tubule." [GOC:tfm] +subset: cellxgene_subset subset: human_reference_atlas subset: kidney_upper_slim synonym: "epithelial cell of renal collecting tubule" EXACT [FMA:70982] @@ -29124,6 +29708,7 @@ relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens id: CL:1000458 name: melanocyte of skin def: "A melanocyte that is part of the skin of body." [GOC:tfm] +subset: cellxgene_subset subset: human_reference_atlas synonym: "skin melanocyte" EXACT [FMA:72144] xref: CALOHA:TS-2374 @@ -29314,6 +29899,7 @@ relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens id: CL:1000487 name: smooth muscle cell of prostate def: "A smooth muscle cell that is part of the prostate gland." [GOC:tfm] +subset: cellxgene_subset subset: human_reference_atlas synonym: "smooth muscle fiber of prostate" EXACT [FMA:84583] xref: FMA:84583 @@ -29327,6 +29913,7 @@ relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens id: CL:1000488 name: cholangiocyte def: "An epithelial cell that is part of the bile duct. Cholangiocytes contribute to bile secretion via net release of bicarbonate and water. They are cuboidal epithelium in the small interlobular bile ducts, but become columnar and mucus secreting in larger bile ducts approaching the porta hepatis and the extrahepatic ducts." [GOC:tfm, PMID:16550043, PMID:18356246] +subset: cellxgene_subset synonym: "epithelial cell of bile duct" EXACT [] xref: FMA:86481 is_a: CL:0000069 {is_inferred="true"} ! branched duct epithelial cell @@ -29364,6 +29951,7 @@ relationship: part_of UBERON:0002358 ! peritoneum id: CL:1000491 name: mesothelial cell of pleura def: "A mesothelial cell that is part of the pleura." [GOC:tfm] +subset: cellxgene_subset synonym: "pleural mesothelial cell" EXACT [FMA:86737] xref: FMA:86737 is_a: CL:0000077 ! mesothelial cell @@ -29385,6 +29973,7 @@ relationship: part_of UBERON:0002400 ! parietal pleura id: CL:1000493 name: mesothelial cell of visceral pleura def: "A mesothelial cell that is part of the visceral pleura." [GOC:tfm] +subset: cellxgene_subset subset: human_reference_atlas xref: FMA:86739 is_a: CL:0000082 ! epithelial cell of lung @@ -29399,6 +29988,7 @@ id: CL:1000494 name: nephron tubule epithelial cell def: "An epithelial cell that is part of a nephron tubule." [GOC:tfm] comment: This needs to be further defined as a juxtamedullary nephron. Will request the juxtamedullary nephron tubule class from UBERON. +subset: cellxgene_subset synonym: "kidney tubule epithelial cell" EXACT [] xref: FMA:86785 xref: KUPO:0001022 @@ -29412,6 +30002,7 @@ relationship: part_of UBERON:0004810 ! nephron tubule epithelium id: CL:1000495 name: small intestine goblet cell def: "A goblet cell that is part of the small intestine." [GOC:tfm] +subset: cellxgene_subset synonym: "goblet cell of epithelium of small intestine" EXACT [] synonym: "goblet cell of small intestine" EXACT [] synonym: "small intestinal goblet cell" EXACT [FMA:86929] @@ -29425,6 +30016,7 @@ intersection_of: part_of UBERON:0002108 ! small intestine id: CL:1000497 name: kidney cell def: "A cell that is part of a kidney." [] +subset: cellxgene_subset xref: KUPO:0001010 is_a: CL:0000000 ! cell intersection_of: CL:0000000 ! cell @@ -29435,6 +30027,7 @@ relationship: part_of UBERON:0002113 ! kidney id: CL:1000500 name: kidney interstitial cell def: "A cell that is part of kidney interstitium." [] +subset: cellxgene_subset subset: kidney_upper_slim xref: KUPO:0001013 is_a: CL:1000497 ! kidney cell @@ -29478,6 +30071,7 @@ relationship: part_of UBERON:0001231 ! nephron tubule [Term] id: CL:1000510 name: kidney glomerular epithelial cell +subset: cellxgene_subset xref: KUPO:0001023 is_a: CL:1000746 ! glomerular cell intersection_of: CL:0002518 ! kidney epithelial cell @@ -29552,6 +30146,7 @@ relationship: part_of UBERON:0005271 ! juxtamedullary cortex id: CL:1000597 name: papillary tips cell def: "A cell that is part of a tip of a renal papilla." [] +subset: cellxgene_subset subset: human_reference_atlas xref: KUPO:0001112 is_a: CL:1000505 ! kidney pelvis cell @@ -29603,6 +30198,7 @@ relationship: part_of UBERON:0001229 ! renal corpuscle [Term] id: CL:1000615 name: kidney cortex tubule cell +subset: cellxgene_subset xref: KUPO:0001024 is_a: CL:0002584 ! renal cortical epithelial cell is_a: CL:1000449 ! epithelial cell of nephron @@ -29672,6 +30268,7 @@ relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: CL:1000692 name: kidney interstitial fibroblast +subset: cellxgene_subset subset: human_reference_atlas xref: KUPO:0001102 is_a: CL:0000057 ! fibroblast @@ -29714,6 +30311,7 @@ is_a: CL:1000500 ! kidney interstitial cell id: CL:1000698 name: kidney resident macrophage def: "A tissue-resident macrophage that is part of some kidney." [] +subset: cellxgene_subset xref: KUPO:0001109 is_a: CL:0000864 ! tissue-resident macrophage is_a: CL:1000500 ! kidney interstitial cell @@ -29738,6 +30336,7 @@ relationship: part_of UBERON:0004227 ! kidney pelvis smooth muscle [Term] id: CL:1000703 name: kidney pelvis urothelial cell +subset: cellxgene_subset xref: KUPO:0001114 is_a: CL:0000731 ! urothelial cell is_a: CL:0002518 {is_inferred="true"} ! kidney epithelial cell @@ -29881,6 +30480,7 @@ relationship: part_of UBERON:0000074 ! renal glomerulus [Term] id: CL:1000768 name: kidney connecting tubule epithelial cell +subset: cellxgene_subset subset: human_reference_atlas subset: kidney_upper_slim xref: KUPO:0001058 @@ -29914,6 +30514,7 @@ relationship: part_of UBERON:0005213 ! outer renal medulla interstitium [Term] id: CL:1000838 name: kidney proximal convoluted tubule epithelial cell +subset: cellxgene_subset xref: KUPO:0001045 is_a: CL:0002306 {is_inferred="true"} ! epithelial cell of proximal tubule intersection_of: CL:0002306 ! epithelial cell of proximal tubule @@ -29923,6 +30524,7 @@ relationship: part_of UBERON:0001287 ! proximal convoluted tubule [Term] id: CL:1000839 name: kidney proximal straight tubule epithelial cell +subset: cellxgene_subset xref: KUPO:0001046 is_a: CL:0002306 {is_inferred="true"} ! epithelial cell of proximal tubule is_a: CL:1000616 {is_inferred="true"} ! kidney outer medulla cell @@ -29934,6 +30536,7 @@ relationship: part_of UBERON:0001290 ! proximal straight tubule [Term] id: CL:1000849 name: kidney distal convoluted tubule epithelial cell +subset: cellxgene_subset subset: human_reference_atlas subset: kidney_upper_slim xref: KUPO:0001056 @@ -29946,6 +30549,7 @@ relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: CL:1000850 name: macula densa epithelial cell +subset: cellxgene_subset subset: human_reference_atlas xref: KUPO:0001057 is_a: CL:0002305 {is_inferred="true"} ! epithelial cell of distal tubule @@ -29979,6 +30583,7 @@ relationship: part_of UBERON:0003644 ! kidney arterial blood vessel [Term] id: CL:1000892 name: kidney capillary endothelial cell +subset: cellxgene_subset subset: kidney_upper_slim xref: KUPO:0001030 is_a: CL:0000071 ! blood vessel endothelial cell @@ -30000,6 +30605,7 @@ relationship: part_of UBERON:0001140 ! renal vein [Term] id: CL:1000909 name: kidney loop of Henle epithelial cell +subset: cellxgene_subset xref: KUPO:0001047 is_a: CL:1000494 {is_inferred="true"} ! nephron tubule epithelial cell intersection_of: CL:1000494 ! nephron tubule epithelial cell @@ -30019,6 +30625,7 @@ relationship: part_of UBERON:0006855 ! muscular coat of ureter [Term] id: CL:1001005 name: glomerular capillary endothelial cell +subset: cellxgene_subset subset: human_reference_atlas xref: KUPO:0001037 is_a: CL:0002144 ! capillary endothelial cell @@ -30053,6 +30660,7 @@ relationship: part_of UBERON:0004640 ! renal efferent arteriole [Term] id: CL:1001016 name: kidney loop of Henle ascending limb epithelial cell +subset: cellxgene_subset subset: kidney_upper_slim xref: KUPO:0001048 is_a: CL:0002305 ! epithelial cell of distal tubule @@ -30075,6 +30683,7 @@ relationship: part_of UBERON:0001289 ! descending limb of loop of Henle id: CL:1001033 name: peritubular capillary endothelial cell def: "An endothelial cell that is part of some peritubular capillary." [] +subset: cellxgene_subset subset: human_reference_atlas xref: KUPO:0001065 is_a: CL:0002144 ! capillary endothelial cell @@ -30098,6 +30707,7 @@ relationship: part_of UBERON:0004726 ! vasa recta [Term] id: CL:1001045 name: kidney cortex artery cell +subset: cellxgene_subset xref: KUPO:0001077 is_a: CL:1000891 {is_inferred="true"} ! kidney arterial blood vessel cell intersection_of: CL:1000891 ! kidney arterial blood vessel cell @@ -30143,6 +30753,7 @@ is_a: CL:1000893 ! kidney venous blood vessel cell [Term] id: CL:1001096 name: kidney afferent arteriole endothelial cell +subset: cellxgene_subset subset: human_reference_atlas xref: KUPO:0001039 is_a: CL:1000412 {is_inferred="true"} ! endothelial cell of arteriole @@ -30165,6 +30776,7 @@ intersection_of: part_of UBERON:0004639 ! renal afferent arteriole [Term] id: CL:1001099 name: kidney efferent arteriole endothelial cell +subset: cellxgene_subset subset: human_reference_atlas xref: KUPO:0001042 is_a: CL:1000412 {is_inferred="true"} ! endothelial cell of arteriole @@ -30187,6 +30799,7 @@ intersection_of: part_of UBERON:0004640 ! renal efferent arteriole id: CL:1001106 name: kidney loop of Henle thick ascending limb epithelial cell def: "An epithelial cell that is part of some loop of Henle thick ascending limb. It is known in some mammalian species that this cell may express the Na+-K+-2Cl− cotransporter (NKCC2) apically." [PMID:25318757] +subset: cellxgene_subset subset: human_reference_atlas xref: KUPO:0001049 is_a: CL:1000504 ! kidney medulla cell @@ -30200,6 +30813,7 @@ relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens id: CL:1001107 name: kidney loop of Henle thin ascending limb epithelial cell def: "An epithelial cell that is part of some loop of Henle thin ascending limb." [] +subset: cellxgene_subset subset: human_reference_atlas xref: KUPO:0001050 is_a: CL:1000617 ! kidney inner medulla cell @@ -30213,6 +30827,7 @@ relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens id: CL:1001108 name: kidney loop of Henle medullary thick ascending limb epithelial cell def: "An epithelial cell that is part of some loop of Henle thick ascending limb segment located in the renal medulla." [] +subset: cellxgene_subset subset: human_reference_atlas xref: KUPO:0001051 is_a: CL:1000616 {is_inferred="true"} ! kidney outer medulla cell @@ -30226,6 +30841,7 @@ relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens id: CL:1001109 name: kidney loop of Henle cortical thick ascending limb epithelial cell def: "An epithelial cell that is part of some loop of Henle thick ascending limb segment located in the renal cortex." [] +subset: cellxgene_subset subset: human_reference_atlas xref: KUPO:0001052 is_a: CL:1001106 ! kidney loop of Henle thick ascending limb epithelial cell @@ -30238,6 +30854,7 @@ relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens id: CL:1001111 name: kidney loop of Henle thin descending limb epithelial cell def: "An epithelial cell that is part of some loop of Henle thin descending limb." [] +subset: cellxgene_subset subset: human_reference_atlas xref: KUPO:0001054 is_a: CL:1000453 ! epithelial cell of intermediate tubule @@ -30292,6 +30909,7 @@ id: CL:1001131 name: vasa recta ascending limb cell def: "A cell that is part of some vasa recta ascending limb." [] comment: It is known in some mammalian species that this cell may express PV-1, a component of the fenestral diaphragm. {xref="PMID:20392799", xref="PMID:20392798", xref="PMID:26062876"} +subset: cellxgene_subset subset: human_reference_atlas xref: KUPO:0001074 is_a: CL:1001036 {is_inferred="true"} ! vasa recta cell @@ -30432,6 +31050,7 @@ intersection_of: part_of UBERON:0005168 ! renal interlobular vein id: CL:1001225 name: kidney collecting duct cell def: "A cell that is part of a collecting duct of renal tubule." [] +subset: cellxgene_subset xref: KUPO:0001012 xref: Wikipedia:Kidney_collecting_duct_cell is_a: CL:1000497 ! kidney cell @@ -30444,6 +31063,7 @@ id: CL:1001285 name: vasa recta descending limb cell def: "A cell that is part of some vasa recta descending limb." [] comment: It is known in some mammalian species that this cell may express the urea transporter B. {xref="PMID:20392799", xref="PMID:20392798", xref="PMID:26062876"} +subset: cellxgene_subset subset: human_reference_atlas xref: KUPO:0001071 is_a: CL:1001036 {is_inferred="true"} ! vasa recta cell @@ -30476,6 +31096,7 @@ relationship: part_of UBERON:0009090 ! outer medulla vasa recta descending limb id: CL:1001318 name: renal interstitial pericyte def: "A pericyte cell located in the kidney interstitium." [] +subset: cellxgene_subset subset: human_reference_atlas xref: KUPO:0001104 is_a: CL:0000669 {is_inferred="true"} ! pericyte @@ -30487,6 +31108,7 @@ relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: CL:1001319 name: bladder cell +subset: cellxgene_subset subset: human_reference_atlas xref: KUPO:0001120 is_a: CL:1000600 ! lower urinary tract cell @@ -30508,6 +31130,7 @@ relationship: part_of UBERON:0000057 ! urethra id: CL:1001428 name: bladder urothelial cell def: "A urothelial cell that is part of the urothelium of the urinary bladder." [doi:10.1038/s41385-022-00565-0] +subset: cellxgene_subset subset: human_reference_atlas synonym: "bladder transitional cell" NARROW [] synonym: "transitional epithelial cell of urinary bladder" NARROW [] @@ -30523,6 +31146,7 @@ relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: CL:1001430 name: urethra urothelial cell +subset: cellxgene_subset xref: KUPO:0001124 is_a: CL:0000731 {is_inferred="true"} ! urothelial cell is_a: CL:1000296 ! epithelial cell of urethra @@ -30533,6 +31157,7 @@ relationship: part_of UBERON:0004787 ! urethra urothelium [Term] id: CL:1001431 name: kidney collecting duct principal cell +subset: cellxgene_subset subset: human_reference_atlas xref: KUPO:0001128 is_a: CL:0005009 {is_inferred="true"} ! renal principal cell @@ -30544,6 +31169,7 @@ relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: CL:1001432 name: kidney collecting duct intercalated cell +subset: cellxgene_subset subset: human_reference_atlas xref: http://en.wikipedia.org/wiki/Collecting_duct_system#Intercalated_cells xref: KUPO:0001129 @@ -30557,6 +31183,7 @@ relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens id: CL:1001433 name: epithelial cell of exocrine pancreas def: "An epithelial cell of the exocrine pancreas." [GOC:tfm] +subset: cellxgene_subset subset: human_reference_atlas synonym: "exocrine pancreas cell" EXACT [] xref: FMA:70986 @@ -30619,6 +31246,7 @@ relationship: RO:0002100 UBERON:0000044 ! has soma location dorsal root ganglion id: CL:1001474 name: medium spiny neuron def: "An inhibitory, GABAergic projection neuron in the striatum that integrates glutamatergic signals arising from the cerebral cortex and thalamus." [doi:10.1073/pnas.242428599, MP:0008462] +subset: cellxgene_subset subset: human_reference_atlas synonym: "gamma-aminobutyric acid (GABA)ergic spiny projection neuron" EXACT [doi:10.1073/pnas.242428599] synonym: "gamma-aminobutyric acid ergic spiny projection neuron" EXACT [doi:10.1073/pnas.242428599] @@ -30671,6 +31299,7 @@ relationship: capable_of GO:0061537 ! glycine secretion, neurotransmission id: CL:1001516 name: intestinal enteroendocrine cell def: "The various hormone- or neurotransmitter-secreting cells present throughout the mucosa of the intestinal tract." [MP:0010802] +subset: cellxgene_subset is_a: CL:0000164 ! enteroendocrine cell is_a: CL:0002563 ! intestinal epithelial cell intersection_of: CL:0000164 ! enteroendocrine cell @@ -30702,7 +31331,7 @@ id: CL:1001566 name: obsolete bronchioalveolar stem cells def: "OBSOLETE. A respiratory stem cell found at the junction of the terminal (conductive) bronchiole and the respiratory bronchiole, which gives rise to alveolar cell types and club cells in response to lung injury." [MP:0011691] comment: Duplicated term - merged into CL:0002638 -property_value: seeAlso "https://github.com/obophenotype/cell-ontology/issues/1443" xsd:string +relationship: term_tracker_item https://github.com/obophenotype/cell-ontology/issues/1443 is_obsolete: true replaced_by: CL:0002638 @@ -30720,6 +31349,7 @@ relationship: part_of UBERON:0000102 ! lung vasculature [Term] id: CL:1001568 name: pulmonary artery endothelial cell +subset: cellxgene_subset subset: human_reference_atlas synonym: "PAEC cell" RELATED [BTO:0001141] xref: BTO:0001141 @@ -30954,6 +31584,7 @@ intersection_of: part_of UBERON:0001155 ! colon id: CL:1001589 name: duodenum glandular cell def: "Glandular cell of duodenal epithelium. Example: Enterocytes, Goblet cells, enteroendocrine cells; Paneth cells; M cells; Brunner's gland cell." [NPX:PDR] +subset: cellxgene_subset synonym: "duodenum glandular cells" RELATED [CALOHA:TS-1275] xref: CALOHA:TS-1275 is_a: CL:1001598 ! small intestine glandular cell @@ -31042,6 +31673,7 @@ relationship: part_of UBERON:0004809 ! salivary gland epithelium id: CL:1001597 name: seminal vesicle glandular cell def: "Glandular cell of seminal vesicle epithelium." [NPX:PDR] +subset: cellxgene_subset synonym: "seminal vesicle glandular cells" RELATED [CALOHA:TS-1283] xref: CALOHA:TS-1283 is_a: CL:0000068 ! duct epithelial cell @@ -31099,6 +31731,7 @@ relationship: part_of UBERON:0001235 ! adrenal cortex id: CL:1001602 name: cerebral cortex endothelial cell def: "Endothelial cells forming the walls of the capillaries within the cerebral cortex." [NPX:PDR] +subset: cellxgene_subset synonym: "cerebral cortex endothelial cells" RELATED [CALOHA:TS-2372] synonym: "endothelial cells of cerebral cortex" RELATED [CALOHA:TS-2372] xref: CALOHA:TS-2372 @@ -31113,6 +31746,7 @@ relationship: part_of UBERON:0013694 ! brain endothelium id: CL:1001603 name: lung macrophage def: "Circulating macrophages and tissue macrophages (alveolar macrophages) of lung." [HPA:HPA, NPX:PDR] +subset: cellxgene_subset synonym: "lung macrophages" RELATED [CALOHA:TS-0576] xref: CALOHA:TS-0576 is_a: CL:0000235 ! macrophage @@ -31205,6 +31839,7 @@ creation_date: 2014-02-03T23:03:09Z id: CL:2000001 name: peripheral blood mononuclear cell def: "A leukocyte with a single non-segmented nucleus in the mature form found in the circulatory pool of blood." [GOC:TermGenie] +subset: cellxgene_subset is_a: CL:0000080 ! circulating cell is_a: CL:0000842 ! mononuclear cell intersection_of: CL:0000842 ! mononuclear cell @@ -31217,6 +31852,7 @@ creation_date: 2014-02-11T17:29:04Z id: CL:2000002 name: decidual cell def: "A specialized, enlarged, connective tissue cell of the decidua with enlarged nucleus, dense membrane‐bound secretory granules and cytoplasmic accumulation of glycogen and lipid droplets. These cells develop by the transformation of endometrial stromal cells during decidualization." [BTO:0002770, NCIT:C32429, PMID:30013421, PMID:30429548, Wiki:Decidual_cells&oldid=937509751, Wiki:Decidualization&oldid=908981933] +subset: cellxgene_subset synonym: "decidua cell" EXACT [BTO:0002770, NCIT:C32429] synonym: "decidual stromal cell" EXACT [BTO:0005756, PMID:11719592] xref: BTO:0002770 @@ -31232,6 +31868,7 @@ creation_date: 2014-02-20T23:06:41Z id: CL:2000004 name: pituitary gland cell def: "Any cell that is part of a pituitary gland." [GOC:TermGenie] +subset: cellxgene_subset is_a: CL:0002319 ! neural cell intersection_of: CL:0000000 ! cell intersection_of: part_of UBERON:0000007 ! pituitary gland @@ -31254,6 +31891,7 @@ creation_date: 2014-03-28T21:35:27Z id: CL:2000006 name: tonsil germinal center B cell def: "Any germinal center B cell that is part of a tonsil." [GOC:TermGenie] +subset: cellxgene_subset is_a: CL:0000844 ! germinal center B cell intersection_of: CL:0000844 ! germinal center B cell intersection_of: part_of UBERON:0002372 ! tonsil @@ -31362,6 +32000,7 @@ creation_date: 2014-06-04T15:29:06Z id: CL:2000016 name: lung microvascular endothelial cell def: "Any lung endothelial cell that is part of a microvascular endothelium." [GOC:TermGenie] +subset: cellxgene_subset is_a: CL:1001567 ! lung endothelial cell is_a: CL:2000008 ! microvascular endothelial cell intersection_of: CL:1001567 ! lung endothelial cell @@ -31384,6 +32023,7 @@ creation_date: 2014-06-04T16:50:33Z id: CL:2000018 name: endothelial cell of coronary artery def: "Any endothelial cell of artery that is part of a coronary artery." [GOC:TermGenie] +subset: cellxgene_subset is_a: CL:0010006 ! cardiac blood vessel endothelial cell is_a: CL:1000413 ! endothelial cell of artery intersection_of: CL:1000413 ! endothelial cell of artery @@ -31419,6 +32059,7 @@ creation_date: 2014-06-24T23:16:53Z id: CL:2000021 name: sebaceous gland cell def: "Any native cell that is part of a sebaceous gland." [GOC:TermGenie] +subset: cellxgene_subset is_a: CL:0000000 ! cell intersection_of: CL:0000000 ! cell intersection_of: part_of UBERON:0001821 ! sebaceous gland @@ -31539,6 +32180,7 @@ id: CL:2000032 name: peripheral nervous system neuron alt_id: CL:0000111 def: "A neuron that is part of a peripheral nervous system." [GOC:TermGenie, ISBN:0721662544] +subset: cellxgene_subset synonym: "peripheral neuron" EXACT [] synonym: "PNS neuron" EXACT [] xref: FMA:84664 @@ -31645,6 +32287,7 @@ creation_date: 2014-07-09T00:04:47Z id: CL:2000041 name: dermis microvascular lymphatic vessel endothelial cell def: "Any dermis lymphatic vessel endothelial cell that is part of a microvascular endothelium." [GOC:TermGenie] +subset: cellxgene_subset is_a: CL:2000011 ! dermis lymphatic vessel endothelial cell intersection_of: CL:2000011 ! dermis lymphatic vessel endothelial cell intersection_of: part_of UBERON:0008339 ! microvascular endothelium @@ -31656,6 +32299,7 @@ creation_date: 2014-07-09T00:09:54Z id: CL:2000042 name: embryonic fibroblast def: "Any fibroblast that is part of a embryo." [GOC:TermGenie] +subset: cellxgene_subset is_a: CL:0000057 ! fibroblast intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0000922 ! embryo @@ -31667,6 +32311,7 @@ creation_date: 2014-07-09T00:12:00Z id: CL:2000043 name: brain pericyte def: "Any pericyte cell that is part of a brain." [GOC:TermGenie] +subset: cellxgene_subset is_a: CL:0002575 ! central nervous system pericyte intersection_of: CL:0000669 ! pericyte intersection_of: part_of UBERON:0000955 ! brain @@ -31701,6 +32346,7 @@ creation_date: 2014-07-09T00:45:07Z id: CL:2000046 name: ventricular cardiac muscle cell def: "Any cardiac muscle cell that is part of a cardiac ventricle." [GOC:TermGenie] +subset: cellxgene_subset is_a: CL:0000746 ! cardiac muscle cell intersection_of: CL:0000746 ! cardiac muscle cell intersection_of: part_of UBERON:0002082 ! cardiac ventricle @@ -31808,6 +32454,7 @@ id: CL:2000055 name: liver dendritic cell def: "Any dendritic cell that is part of a liver." [GOC:TermGenie] comment: http://www.jleukbio.org/content/66/2/322.abstract +subset: cellxgene_subset synonym: "hepatic dendritic cell" EXACT [] is_a: CL:0000451 ! dendritic cell intersection_of: CL:0000451 ! dendritic cell @@ -31854,6 +32501,7 @@ id: CL:2000059 name: prostate gland microvascular endothelial cell def: "Any microvascular endothelial cell that is part of a prostate gland." [GOC:TermGenie] comment: http://www.sciencellonline.com/site/productInformation.php?keyword=4400 +subset: cellxgene_subset is_a: CL:2000008 ! microvascular endothelial cell intersection_of: CL:2000008 ! microvascular endothelial cell intersection_of: part_of UBERON:0002367 ! prostate gland @@ -31866,6 +32514,7 @@ id: CL:2000060 name: placental villous trophoblast def: "A trophoblast of placental villi. These cells fuse to form synctial trophoplast - the placental side of the interface between the placenta and maternal blood sinusoids in the decidua." [PMID:31049600] comment: Same as synctial trophoblast? +subset: cellxgene_subset synonym: "vCTB" EXACT [PMID:31049600] synonym: "villous cytotrophoblast" EXACT [] xref: BTO:0006119 @@ -31922,6 +32571,7 @@ id: CL:2000064 name: ovarian surface epithelial cell def: "Any epithelial cell that is part of a female gonad." [GOC:TermGenie] comment: http://www.sciencellonline.com/site/productInformation.php?keyword=7310 +subset: cellxgene_subset is_a: CL:0000066 ! epithelial cell intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0000992 ! ovary @@ -32262,6 +32912,7 @@ creation_date: 2015-03-31T21:02:36Z id: CL:2000092 name: hair follicular keratinocyte def: "Any keratinocyte that is part of a hair follicle." [GOC:TermGenie] +subset: cellxgene_subset is_a: CL:0000312 ! keratinocyte is_a: CL:0002559 ! hair follicle cell intersection_of: CL:0000312 ! keratinocyte @@ -32273,6 +32924,7 @@ creation_date: 2015-03-31T21:07:02Z id: CL:2000093 name: bronchus fibroblast of lung def: "Any fibroblast of lung that is part of a bronchus." [GOC:TermGenie] +subset: cellxgene_subset is_a: CL:0002553 ! fibroblast of lung intersection_of: CL:0002553 ! fibroblast of lung intersection_of: part_of UBERON:0002185 ! bronchus @@ -32295,6 +32947,7 @@ creation_date: 2015-03-31T22:25:17Z id: CL:2000095 name: cord blood hematopoietic stem cell def: "Any hematopoietic stem cell that is part of a umbilical cord blood." [GOC:TermGenie] +subset: cellxgene_subset is_a: CL:0002246 ! peripheral blood stem cell is_a: CL:0002352 ! gestational hematopoietic stem cell intersection_of: CL:0000037 ! hematopoietic stem cell @@ -32343,6 +32996,7 @@ id: CL:3000001 name: Hofbauer cell def: "A tissue-resident macrophage that is part of the placenta. A Hofbauer cell expresses high levels of growth factors and metalloproteinases that support vasculogenesis, angiogenesis, branching morphogenesis and tissue remodeling. A Hofbauer cell has a fetal origin and is present throughout pregnancy." [GOC:CellBLAST, PMID:30429548, PMID:30498493, PMID:34745147, PMID:35438172] comment: Hofbauer cells are a heterogenic group of macrophages that resemble M2-like cells. Initially described in chorionic villi in humans, a Hofbauer cell is now often used to describe any fetal-derived placental macrophage that resides within the placental villous core, amnion, and chorion laeve. {xref="PMID:30498493"} +subset: cellxgene_subset synonym: "HBC" RELATED OMO:0003000 [] is_a: CL:0000864 ! tissue-resident macrophage relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 @@ -32389,6 +33043,7 @@ creation_date: 2019-02-25T19:34:33Z id: CL:4006000 name: fibroblast of breast def: "A fibroblast that is part of the breast." [] +subset: cellxgene_subset synonym: "breast fibroblast" EXACT [] is_a: CL:0000057 ! fibroblast intersection_of: CL:0000057 ! fibroblast @@ -32530,6 +33185,7 @@ id: CL:4023011 name: lamp5 GABAergic cortical interneuron def: "A GABAergic neuron located in the cerebral cortex that expresses Lamp5" [PMID:30382198] subset: BDS_subset +subset: cellxgene_subset xref: ILX:0770149 is_a: CL:0010011 ! cerebral cortex GABAergic interneuron intersection_of: CL:0000099 ! interneuron @@ -32545,6 +33201,7 @@ id: CL:4023012 name: near-projecting glutamatergic cortical neuron def: "A glutamatergic neuron located in the cerebral cortex that projects axons locally rather than distantly." [DOI:10.1101/2020.10.19.343129] subset: BDS_subset +subset: cellxgene_subset subset: human_reference_atlas synonym: "NP neuron" EXACT [] xref: ILX:0770103 @@ -32563,6 +33220,7 @@ id: CL:4023013 name: corticothalamic-projecting glutamatergic cortical neuron def: "A glutamatergic neuron located in the cerebral cortex that projects to the thalamus." [DOI:10.1101/2020.10.19.343129] subset: BDS_subset +subset: cellxgene_subset subset: human_reference_atlas synonym: "CT projecting neuron" EXACT [] is_a: CL:0000679 ! glutamatergic neuron @@ -32593,6 +33251,7 @@ id: CL:4023015 name: sncg GABAergic cortical interneuron def: "A GABAergic neuron located in the cerebral cortex that expresses Gamma-synuclein" [PMID:33186530] subset: BDS_subset +subset: cellxgene_subset xref: ILX:0770150 is_a: CL:0010011 ! cerebral cortex GABAergic interneuron intersection_of: CL:0000099 ! interneuron @@ -32608,6 +33267,7 @@ id: CL:4023016 name: vip GABAergic cortical interneuron def: "A GABAergic neuron located in the cerebral cortex that expresses vasoactive intestinal polypeptide" [PMID:33186530] subset: BDS_subset +subset: cellxgene_subset xref: ILX:0770151 is_a: CL:0010011 ! cerebral cortex GABAergic interneuron intersection_of: CL:0000099 ! interneuron @@ -32623,6 +33283,7 @@ id: CL:4023017 name: sst GABAergic cortical interneuron def: "A GABAergic neuron located in the cerebral cortex that expresses somatostatin (sst)" [PMID:27477017] subset: BDS_subset +subset: cellxgene_subset xref: ILX:0770152 is_a: CL:0010011 ! cerebral cortex GABAergic interneuron intersection_of: CL:0000099 ! interneuron @@ -32638,6 +33299,7 @@ id: CL:4023018 name: pvalb GABAergic cortical interneuron def: "A GABAergic interneuron located in the cerebral cortex that expresses Parvalbumin." [PMID:27477017] subset: BDS_subset +subset: cellxgene_subset xref: ILX:0770154 is_a: CL:0010011 ! cerebral cortex GABAergic interneuron intersection_of: CL:0000099 ! interneuron @@ -32806,6 +33468,7 @@ property_value: IAO:0000028 "L4 sst interneuron (Mus)" xsd:string id: CL:4023032 name: ON retinal ganglion cell comment: A retinal ganglion cell that is depolarized by illumination of its receptive field center. {xref="PMID:19602302"} +subset: cellxgene_subset is_a: CL:0000740 ! retinal ganglion cell relationship: dc-contributor http://orcid.org/0000-0001-7258-9596 @@ -32813,6 +33476,7 @@ relationship: dc-contributor http://orcid.org/0000-0001-7258-9596 id: CL:4023033 name: OFF retinal ganglion cell def: "A retinal ganglion cell that is depolarized by decreased illumination of their receptive field center." [PMID:19602302] +subset: cellxgene_subset is_a: CL:0000740 ! retinal ganglion cell relationship: dc-contributor http://orcid.org/0000-0001-7258-9596 @@ -32820,18 +33484,32 @@ relationship: dc-contributor http://orcid.org/0000-0001-7258-9596 id: CL:4023034 name: obsolete L2/3 pvalb-like sst GABAergic cortical interneuron (Mus musculus) def: "OBSOLETE A sst GABAergic cortical interneuron transcriptomically between the sst and the pvalb families with a soma found in L2/3. Some L2/3 PV-like sst cells have Martinotti morphology while some have basket cell morphology. L2/3 PV-like sst cells have lower AP width and higher firing rate than typical Sst subclass cells. L2/3 PV-like sst cells have high maximum firing rate variability, with many classified as belonging to the pvalb subclass on the basis of electrophysiology." [PMID:33184512] -comment: Moved to PCL - see https://github.com/obophenotype/brain_data_standards_ontologies/issues/231. Use PCL:1000002 instead. +comment: Moved to PCL. Use PCL:1000002 instead. synonym: "L2/3 PV-like SST Mus)" EXACT [] relationship: dc-contributor https://orcid.org/0000-0001-7258-9596 +relationship: term_tracker_item https://github.com/obophenotype/brain_data_standards_ontologies/issues/231 is_obsolete: true replaced_by: PCL:1000002 +[Term] +id: CL:4023035 +name: lateral ganglionic eminence derived neuron +def: "A neuron that is derived from a precursor cell in the lateral ganglion eminence." [wikipediaversioned:Ganglionic_eminence&oldid=1186824360] +synonym: "LGE-derived neuron" EXACT [PMID:10377350] +is_a: CL:0000540 ! neuron +intersection_of: CL:0000540 ! neuron +intersection_of: develops_from UBERON:0004025 ! lateral ganglionic eminence +relationship: develops_from UBERON:0004025 ! lateral ganglionic eminence +property_value: dc-contributor "https://orcid.org/0000-0001-7258-9596" xsd:string +property_value: dc-contributor "https://orcid.org/0000-0002-7073-9172" xsd:string + [Term] id: CL:4023036 name: chandelier pvalb GABAergic cortical interneuron def: "A pvalb GABAergic cortical interneuron that is recognizable by the straight terminal axonal 'cartridges' of vertically oriented strings of synaptic boutons. Chandelier PV cells' boutons target exclusively the axon initial segment (AIS) of pyramidal cells, with a single cell innervating hundreds of pyramidal cells in a clustered manner." [PMID:27477017] comment: In mice, Chandelier PV cells have soma found in in upper L2/3, with some in deep L5 and exhibit fast-spiking but lower firing rate compared to basket cells, and have practically absent hyperpolarization sag. {xref="PMID:27477017"} subset: BDS_subset +subset: cellxgene_subset synonym: "Chandelier PV" EXACT [] xref: ILX:0107356 is_a: CL:4023018 ! pvalb GABAergic cortical interneuron @@ -32844,6 +33522,7 @@ id: CL:4023038 name: L6b glutamatergic cortical neuron def: "A glutamatergic neuron with a soma found in cortical layer 6b. They are transcriptomically related to corticothalamic-projecting neurons but have differential projections to the thalamus or anterior cingulate." [DOI:10.1101/2020.10.19.34312, PMID:30382198] subset: BDS_subset +subset: cellxgene_subset xref: ILX:0770163 is_a: CL:0000679 ! glutamatergic neuron is_a: CL:0010012 ! cerebral cortex neuron @@ -32872,6 +33551,7 @@ id: CL:4023040 name: L2/3-6 intratelencephalic projecting glutamatergic neuron def: "A intratelencephalic-projecting glutamatergic neuron with a soma found in cortical layers L2/3-6" [DOI:10.1101/2020.10.19.343129] subset: BDS_subset +subset: cellxgene_subset synonym: "L2/3-6 IT projecting neuron" EXACT [] is_a: CL:4023008 ! intratelencephalic-projecting glutamatergic cortical neuron relationship: dc-contributor https://orcid.org/0000-0001-7258-9596 @@ -32882,6 +33562,7 @@ id: CL:4023041 name: L5 extratelencephalic projecting glutamatergic cortical neuron def: "A glutamatergic neuron, with a soma found in the deeper portion of L5, that has long-range axonal projections including deep subcortical targets outside of the telencephalon and, in some cases, the spinal cord. While the L5 ET neuron projections are not limited to ET targets, they are clearly differentiated from the neuron subclasses whose projections are constrained to intratelencephalic (IT) targets. L5 ET neurons are generally the largest excitatory cortical neurons, typically having a thick apical dendrite with a prominent dendritic tuft in layer 1 and displaying burst-firing physiological characteristics." [DOI:10.1101/2020.10.19.343129] subset: BDS_subset +subset: cellxgene_subset synonym: "burst-firing layer 5 neuron" EXACT [DOI:10.3389/fncel.2011.00001] synonym: "L5b neuron" RELATED OMO:0003000 [DOI:10.1016/j.neuron.2011.07.029] synonym: "pyramidal tract (PT) neuron" NARROW [DOI:10.1038/nrn3469] @@ -32901,6 +33582,7 @@ id: CL:4023042 name: L6 corticothalamic-projecting glutamatergic cortical neuron def: "A corticothalamic-projecting neuron with a soma found in cortical layer 6." [DOI:10.1101/2020.10.19.343129] subset: BDS_subset +subset: cellxgene_subset synonym: "L6 CT" EXACT [] is_a: CL:4023013 ! corticothalamic-projecting glutamatergic cortical neuron intersection_of: CL:4023013 ! corticothalamic-projecting glutamatergic cortical neuron @@ -32915,6 +33597,7 @@ id: CL:4023043 name: L5/6 near-projecting glutamatergic neuron of the primary motor cortex def: "A near-projecting glutamatergic neuron with a soma found in layer 5/6 of the primary motor cortex." [DOI:10.1101/2020.10.19.343129, PMID:31209381] subset: BDS_subset +subset: cellxgene_subset synonym: "L5/6 NP M1" EXACT [] synonym: "L5/6 NP MOp" EXACT [] xref: ILX:0770161 @@ -32968,6 +33651,7 @@ id: CL:4023047 name: L2/3 intratelencephalic projecting glutamatergic neuron of the primary motor cortex def: "An intratelencephalic-projecting glutamatergic neuron with a soma found in cortical layer 2/3 of the primary motor cortex." [DOI:10.1101/2020.10.19.343129] subset: BDS_subset +subset: cellxgene_subset synonym: "L2/3 IT M1" EXACT [] synonym: "L2/3 IT MOp" EXACT [] is_a: CL:4030059 ! L2/3 intratelencephalic projecting glutamatergic neuron @@ -32982,6 +33666,7 @@ id: CL:4023048 name: L4/5 intratelencephalic projecting glutamatergic neuron of the primary motor cortex def: "An intratelencephalic-projecting glutamatergic with a soma located in upper L5 of the primary motor cortex. These cells have thin untufted apical dendrites." [PMID:33184512] subset: BDS_subset +subset: cellxgene_subset synonym: "L4/5 IT M1" EXACT [] synonym: "L4/5 IT MOp" EXACT [] xref: ILX:0770174 @@ -33012,6 +33697,7 @@ id: CL:4023050 name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex def: "An intratelencephalic-projecting glutamatergic neuron with a soma found in L6 of the primary motor cortex. These cells are short untufted pyramidal cells, which could be stellate or inverted." [PMID:9236245] subset: BDS_subset +subset: cellxgene_subset synonym: "L6 IT M1" EXACT [] synonym: "L6 IT MOp" EXACT [] xref: ILX:0770158 @@ -33028,6 +33714,7 @@ id: CL:4023051 name: vascular leptomeningeal cell def: "A type of mesothelial fibroblast that is derived from the neural crest, is localized on blood vessels, and is a key component of the pia and arachnoid membranes surrounding the brain." [PMID:27284195, PMID:29443965, PMID:30096314] subset: BDS_subset +subset: cellxgene_subset synonym: "VLMC" EXACT [] xref: ILX:0770143 is_a: CL:4023058 ! mesothelial fibroblast of the leptomeninx @@ -33057,6 +33744,7 @@ relationship: RO:0002120 CL:0005000 ! synapsed to spinal cord interneuron id: CL:4023054 name: mesothelial fibroblast def: "A mesothelial cell that has undergone mesothelial-to-mesenchymal transition (MMT) to become a fibroblast cell." [PMID:26106328] +subset: cellxgene_subset is_a: CL:0000057 ! fibroblast relationship: dc-contributor https://orcid.org/0000-0001-7258-9596 relationship: develops_from CL:0000077 ! mesothelial cell @@ -33080,6 +33768,7 @@ id: CL:4023056 name: vascular leptomeningeal cell (Mmus) def: "A type of mouse mesothelial fibroblast that is derived from the neural crest, is localized on blood vessels, and is a key component of the pia and arachnoid membranes surrounding the brain." [PMID:30096314] subset: BDS_subset +subset: cellxgene_subset synonym: "VLMC (Mus musculus)" EXACT [] is_a: CL:4023051 ! vascular leptomeningeal cell relationship: dc-contributor https://orcid.org/0000-0001-7258-9596 @@ -33118,6 +33807,7 @@ id: CL:4023059 name: differentiation-committed oligodendrocyte precursor def: "An oligodendrocyte precursor cell that is committed to differentiate." [PMID:32066987] comment: COPs are distinct from OPCs in that the lack expression of Pdgfra and Cspg4 and come out as distinct clusters in transcriptomic profiling. This is the reason that this term is not modelled as a subclassOf OPC but instead linked using develops_from. {xref="PMID:27284195"} +subset: cellxgene_subset subset: human_reference_atlas synonym: "committed oligodendrocyte precursor" EXACT [] synonym: "COP" EXACT OMO:0003000 [] @@ -33191,6 +33881,7 @@ id: CL:4023065 name: meis2 expressing cortical GABAergic cell def: "A GABAergic cell located in the cerebral cortex that expresses meis2." [PMID:33372656] subset: BDS_subset +subset: cellxgene_subset is_a: CL:0000617 ! GABAergic neuron is_a: CL:0010012 ! cerebral cortex neuron relationship: dc-contributor https://orcid.org/0000-0001-7258-9596 @@ -33213,9 +33904,10 @@ relationship: dc-contributor https://orcid.org/0000-0001-7258-9596 id: CL:4023067 name: obsolete Martinotti morphology L2/3 pvalb-like sst GABAergic cortical interneuron (Mus musculus) def: "OBSOLETE A L2/3 pvalb-like sst GABAergic cortical interneuron (Mus musculus) that has Martinotti morphology." [PMID:33184512] -comment: Moved to PCL - see https://github.com/obophenotype/brain_data_standards_ontologies/issues/231. Use PCL:1000004 instead. +comment: Moved to PCL. Use PCL:1000004 instead. synonym: "Martinotti L2/3 PV-like SST (Mus)" EXACT [] relationship: dc-contributor https://orcid.org/0000-0001-7258-9596 +relationship: term_tracker_item https://github.com/obophenotype/brain_data_standards_ontologies/issues/231 is_obsolete: true replaced_by: PCL:1000004 @@ -33251,6 +33943,7 @@ property_value: IAO:0000028 "MGE cortical gaba interneuron" xsd:string id: CL:4023070 name: caudal ganglionic eminence derived GABAergic cortical interneuron def: "A GABAergic cortical interneuron that develops from the caudal ganglionic eminence and has migrated to the cerebral cortex." [PMID:20130169] +subset: cellxgene_subset synonym: "CGE cortical interneuron" EXACT [] is_a: CL:0010011 ! cerebral cortex GABAergic interneuron is_a: CL:4023064 ! caudal ganglionic eminence derived interneuron @@ -33290,8 +33983,8 @@ relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens id: CL:4023073 name: obsolete choroid plexus cell def: "OBSOLETE. A cell that is part of the choroid plexus." [DOI:10.1101/2022.10.12.511898] -comment: https://github.com/obophenotype/cell-ontology/issues/2043 relationship: dc-contributor http://orcid.org/0000-0001-7258-9596 +relationship: term_tracker_item https://github.com/obophenotype/cell-ontology/issues/2043 is_obsolete: true replaced_by: CL:0000706 @@ -33353,9 +34046,10 @@ relationship: dc-contributor https://orcid.org/0000-0001-7258-9596 id: CL:4023078 name: obsolete basket morphology L2/3 pvalb-like sst GABAergic cortical interneuron (Mus musculus) def: "OBSOLETE A L2/3 pvalb-like sst GABAergic cortical interneuron (Mus musculus) that has basket morphology." [PMID:33184512] -comment: Moved to PCL - see https://github.com/obophenotype/brain_data_standards_ontologies/issues/231. Use PCL:1000003 instead. +comment: Moved to PCL. Use PCL:1000003 instead. synonym: "basket L2/3 PV-like SST (Mus)" EXACT [] relationship: dc-contributor https://orcid.org/0000-0001-7258-9596 +relationship: term_tracker_item https://github.com/obophenotype/brain_data_standards_ontologies/issues/231 is_obsolete: true replaced_by: PCL:1000003 @@ -33780,6 +34474,7 @@ relationship: part_of UBERON:0002227 ! spiral organ of cochlea id: CL:4023121 name: sst chodl GABAergic cortical interneuron def: "A sst GABAergic cortical interneuron that also expresses Chodl. These neurons are rare and correspond to the only known cortical interneurons with long-range projection." [PMID:15845086, PMID:31209381, PMID:33372656] +subset: cellxgene_subset synonym: "long-range GABAergic interneuron" BROAD [] is_a: CL:4023017 ! sst GABAergic cortical interneuron relationship: dc-contributor https://orcid.org/0000-0001-7258-9596 @@ -34004,6 +34699,7 @@ relationship: dc-contributor http://orcid.org/0000-0001-7258-9596 id: CL:4023181 name: hypendymal cell def: "A neurecto-epithelial cell that is part of the basal layer of the subcommissural organ and specializes in the secretion of proteins into the subarachnoid space. Hypendymal cells have similar characteristics to ependymal cells and express SCO-spondin." [https://orcid.org/0000-0001-7258-9596, PMID:26778959, PMID:9579598] +subset: cellxgene_subset is_a: CL:0000710 ! neurecto-epithelial cell is_a: CL:0002319 ! neural cell relationship: dc-contributor http://orcid.org/0000-0002-2105-0715 @@ -34098,6 +34794,7 @@ creation_date: 2021-11-23T03:23:53Z id: CL:4028004 name: alveolar type 1 fibroblast cell def: "A pulmonary interstitial fibroblast that is part of the alveolus and contains lipid droplets." [PMID:22268140, PMID:26706109, PMID:28886382, PMID:29489752, PMID:30675802, PMID:33624948, PMID:33707239, PMID:9074756] +subset: cellxgene_subset subset: human_reference_atlas synonym: "AF1" RELATED OMO:0003000 [] synonym: "alveolar fibroblast" BROAD [] @@ -34120,6 +34817,7 @@ creation_date: 2021-12-09T15:34:13Z id: CL:4028006 name: alveolar type 2 fibroblast cell def: "A pulmonary interstitial fibroblast that is part of the alveolus and localizes to vascular adventitia." [PMID:26706109, PMID:28886382, PMID:29752282, PMID:30675802, PMID:33208946, PMID:33624948] +subset: cellxgene_subset subset: human_reference_atlas synonym: "adventitial fibroblast" BROAD [] synonym: "AF2" RELATED OMO:0003000 [] @@ -34267,6 +34965,7 @@ property_value: dcterms-date "2022-03-11T14:38:32Z" xsd:dateTime id: CL:4030009 name: epithelial cell of proximal tubule segment 1 def: "Epithelial cell that is part of segment 1 (S1) of the proximal tubule epithelium." [PMID:31249312] +subset: cellxgene_subset subset: human_reference_atlas synonym: "epithelial cell of segment 1 of proximal tubule" EXACT [] is_a: CL:0002306 ! epithelial cell of proximal tubule @@ -34287,6 +34986,7 @@ property_value: dcterms-date "2022-05-10T13:26:13Z" xsd:dateTime id: CL:4030011 name: epithelial cell of proximal tubule segment 3 def: "Epithelial cell that is part of segment 3 (S3) of the proximal tubule epithelium." [PMID:31249312] +subset: cellxgene_subset subset: human_reference_atlas synonym: "epithelial cell of segment 3 of proximal tubule" EXACT [] is_a: CL:0002306 ! epithelial cell of proximal tubule @@ -34372,6 +35072,7 @@ property_value: dcterms-date "2022-06-21T13:51:46Z" xsd:dateTime id: CL:4030018 name: kidney connecting tubule principal cell def: "A renal principal cell located in the connecting tubule." [http://orcid.org/0000-0003-2804-127X, PMID:27582101, PMID:31249312] +subset: cellxgene_subset subset: human_reference_atlas is_a: CL:0005009 ! renal principal cell is_a: CL:1000768 ! kidney connecting tubule epithelial cell @@ -34438,6 +35139,7 @@ property_value: dcterms-date "2022-07-05T12:13:40Z" xsd:dateTime id: CL:4030023 name: respiratory hillock cell def: "A hillock cell that is located in respiratory epithelium. In some mammalian species, this cell type has been noted to express KRT13 and KRT4 and is postulated to play a role in squamous barrier function and immunomodulation." [https://orcid.org/0000-0001-7772-9578, PMID:30069044, PMID:32726565, PMID:33442032] +subset: cellxgene_subset synonym: "hillock cell of respiratory tract" NARROW [] is_a: CL:0002368 ! respiratory epithelial cell is_a: CL:4030024 ! hillock cell @@ -34468,6 +35170,7 @@ property_value: dcterms-date "2022-07-05T15:50:17Z" xsd:dateTime id: CL:4030026 name: BEST4+ intestinal epithelial cell, human def: "An absorptive epithelial cell of the human intestine expressing bestrophin-4 (BEST4) calcium-activated ion channels." [https://orcid.org/0000-0002-7431-4139, PMID:24223998, PMID:35176508] +subset: cellxgene_subset is_a: CL:0000255 ! eukaryotic cell is_a: CL:0000677 ! gut absorptive cell relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens @@ -34478,6 +35181,7 @@ property_value: dcterms-date "2022-09-07T12:34:20Z" xsd:dateTime id: CL:4030027 name: GABAergic amacrine cell def: "An amacrine cell that uses GABA as a neurotransmitter." [https://doi.org/10.1016/j.cell.2020.08.013] +subset: cellxgene_subset synonym: "amacrine cell, GABAergic" EXACT [] is_a: CL:0000561 ! amacrine cell is_a: CL:0011005 ! GABAergic interneuron @@ -34489,6 +35193,7 @@ property_value: dcterms-date "2022-10-17T12:35:11Z" xsd:dateTime id: CL:4030028 name: glycinergic amacrine cell def: "An amacrine cell that uses glycine as a neurotransmitter." [] {def="https://doi.org/10.1016/j.cell.2020.08.013"} +subset: cellxgene_subset subset: human_reference_atlas synonym: "amacrine cell, glycinergic" EXACT [] is_a: CL:0000561 ! amacrine cell @@ -35803,6 +36508,45 @@ intersection_of: part_of UBERON:0006841 ! central vein of liver relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 relationship: part_of UBERON:0006841 ! central vein of liver +[Term] +id: CL:4033062 +name: interstitial extravillous trophoblast cell +def: "A trophoblast cell that invades the uterine wall to anchor the placenta to the uterus. An interstitial extravillous trophoblast cell differentiates from an extravillous trophoblast cell, becoming hyperchromatic and changing its morphology to a fibroblast-like spindle-shaped cell. In humans, this cell can be distinguished by the expression of placental-specific protein 8, which stimulates migration." [doi:10.1007/978-3-030-84725-8, PMID:37630754] +synonym: "iEVT" RELATED OMO:0003000 [PMID:37630754] +synonym: "interstitial extravillous trophoblast" RELATED [PMID:37630754] +synonym: "interstitial trophoblast" RELATED [PMID:11337369] +synonym: "invasive interstitial extravillous trophoblast cell" EXACT [doi:10.1007/978-3-030-84725-8] +is_a: CL:0000351 ! trophoblast cell +relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 +relationship: develops_from CL:0008036 ! extravillous trophoblast +property_value: dcterms-date "2024-01-08T15:43:15Z" xsd:dateTime + +[Term] +id: CL:4033063 +name: endovascular extravillous trophoblast cell +def: "A trophoblast cell that invades the maternal spiral arteries and replace the endothelial lining, remodeling the vessels and allowing for adequate blood transport into the placenta. An endovascular extravillous trophoblast cell differentiates from an extravillous trophoblast cell. In humans, this cell can be distinguished by the expression of CD56." [doi:10.1007/978-3-030-84725-8, PMID:37630754] +comment: Shortly after implantation, the endovascular extravillous trophoblast cells occlude the maternal spiral arteries, preventing premature oxygen delivery to the placental villi and reducing fetal oxidative stress. {xref="PMID:37630754"} +synonym: "eEVT" RELATED OMO:0003000 [PMID:37630754] +synonym: "endovascular extravillous trophoblast" RELATED [PMID:37630754] +synonym: "endovascular trophoblast" RELATED [PMID:11337369] +is_a: CL:0000351 ! trophoblast cell +relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 +relationship: develops_from CL:0008036 ! extravillous trophoblast +property_value: dcterms-date "2024-01-08T15:43:32Z" xsd:dateTime + +[Term] +id: CL:4033064 +name: uterine resident macrophage +def: "A tissue-resident macrophage that is part of the uterus." [PMID:36113384] +comment: Uterine macrophages are reported to be evenly distributed throughout the endometrial stroma but with aggregations observed close to the lumen of superficial secretory glands. {xref="PMID:36113384"} +synonym: "uterine macrophage" BROAD [PMID:36113384] +is_a: CL:0000864 ! tissue-resident macrophage +intersection_of: CL:0000864 ! tissue-resident macrophage +intersection_of: part_of UBERON:0000995 ! uterus +relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 +relationship: part_of UBERON:0000995 ! uterus +property_value: dcterms-date "2024-01-08T16:05:09Z" xsd:dateTime + [Term] id: CL:4040000 name: glial restricted tripotential precursor cell @@ -40803,7 +41547,6 @@ synonym: "nitric oxide production involved in acute inflammatory response" BROAD synonym: "production of nitric oxide involved in acute inflammatory response" BROAD [] synonym: "production of nitric oxide involved in inflammatory response" EXACT [] is_a: GO:0002532 ! production of molecular mediator involved in inflammatory response -relationship: has_primary_output CHEBI:16480 [Term] id: GO:0002538 @@ -46172,8 +46915,8 @@ subset: goslim_flybase_ribbon subset: goslim_generic subset: goslim_mouse subset: goslim_plant +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset synonym: "microtubule/chromatin interaction" RELATED [] synonym: "plasmid binding" NARROW [] synonym: "structure specific DNA binding" RELATED [] @@ -46229,8 +46972,8 @@ subset: goslim_flybase_ribbon subset: goslim_generic subset: goslim_mouse subset: goslim_plant +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset synonym: "base pairing with RNA" NARROW [] synonym: "poly(A) RNA binding" RELATED [] synonym: "poly(A)-RNA binding" RELATED [] @@ -47089,7 +47832,7 @@ subset: goslim_metagenomics subset: goslim_mouse subset: goslim_pir subset: goslim_plant -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "carrier" RELATED [] xref: Reactome:R-HSA-168313 "Virion-associated M2 protein mediated ion infusion" xref: Reactome:R-HSA-178215 "SMAD7:SMURF1 complex is exported to the cytosol" @@ -47500,7 +48243,7 @@ id: GO:0005575 name: cellular_component namespace: cellular_component alt_id: GO:0008372 -def: "A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex)." [GOC:pdt] +def: "A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex)." [GOC:pdt] comment: Note that, in addition to forming the root of the cellular component ontology, this term is recommended for the annotation of gene products whose cellular component is unknown. When this term is used for annotation, it indicates that no information was available about the cellular component of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this. subset: goslim_candida subset: goslim_chembl @@ -47531,8 +48274,8 @@ subset: goslim_metagenomics subset: goslim_mouse subset: goslim_pir subset: goslim_plant +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset synonym: "extracellular" EXACT [] xref: Wikipedia:Extracellular is_a: GO:0110165 ! cellular anatomical entity @@ -47618,7 +48361,7 @@ comment: Note that for multicellular organisms, the extracellular space refers t subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "intercellular space" RELATED [] xref: NIF_Subcellular:sao1425028079 is_a: GO:0110165 ! cellular anatomical entity @@ -47712,8 +48455,8 @@ subset: goslim_flybase_ribbon subset: goslim_generic subset: goslim_metagenomics subset: goslim_pir +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset synonym: "chromatid" RELATED [] synonym: "interphase chromosome" NARROW [] synonym: "prophase chromosome" NARROW [] @@ -47747,8 +48490,8 @@ subset: goslim_chembl subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset xref: Wikipedia:Cytoplasm is_a: GO:0110165 ! cellular anatomical entity relationship: part_of GO:0005622 ! intracellular anatomical structure @@ -47895,8 +48638,8 @@ subset: goslim_generic subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset synonym: "free ribosome" NARROW [NIF_Subcellular:sao1139385046] synonym: "membrane bound ribosome" NARROW [NIF_Subcellular:sao1291545653] synonym: "ribosomal RNA" RELATED [] @@ -47921,8 +48664,8 @@ subset: goslim_generic subset: goslim_mouse subset: goslim_pir subset: goslim_plant +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset xref: Wikipedia:Cytoskeleton is_a: GO:0043232 ! intracellular non-membrane-bounded organelle @@ -48012,8 +48755,8 @@ subset: goslim_generic subset: goslim_metagenomics subset: goslim_mouse subset: goslim_plant +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset synonym: "bacterial inner membrane" NARROW [] synonym: "cell membrane" EXACT [] synonym: "cellular membrane" EXACT [NIF_Subcellular:sao6433132645] @@ -48163,8 +48906,8 @@ subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant subset: goslim_pombe +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset synonym: "carbohydrate metabolism" EXACT [] xref: Wikipedia:Carbohydrate_metabolism is_a: GO:0044238 ! primary metabolic process @@ -48375,8 +49118,8 @@ subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant subset: goslim_pombe +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset synonym: "energy pathways" BROAD [] synonym: "intermediary metabolism" RELATED [GOC:mah] synonym: "metabolic energy generation" RELATED [] @@ -48530,8 +49273,8 @@ def: "Any process in which a new genotype is formed by reassortment of genes res subset: goslim_drosophila subset: goslim_generic subset: goslim_pombe +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset is_a: GO:0006259 ! DNA metabolic process [Term] @@ -48639,7 +49382,7 @@ subset: goslim_drosophila subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "protein anabolism" EXACT [] synonym: "protein biosynthesis" EXACT [] synonym: "protein biosynthetic process" EXACT [] @@ -48827,18 +49570,16 @@ subset: goslim_drosophila subset: goslim_generic subset: goslim_pir subset: goslim_pombe +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset synonym: "amino acid and derivative metabolism" RELATED [] synonym: "cellular amino acid and derivative metabolic process" RELATED [] synonym: "cellular amino acid metabolic process" EXACT [] synonym: "cellular amino acid metabolism" EXACT [] -is_a: GO:0019752 ! carboxylic acid metabolic process is_a: GO:0044238 ! primary metabolic process -is_a: GO:1901564 ! organonitrogen compound metabolic process intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:37022 -relationship: has_primary_input_or_output CHEBI:37022 +intersection_of: has_primary_input_or_output CHEBI:35238 +relationship: has_primary_input_or_output CHEBI:35238 property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/17904" xsd:anyURI [Term] @@ -48849,7 +49590,6 @@ def: "Any process that modulates the frequency, rate or extent of the chemical r synonym: "regulation of amino acid metabolism" EXACT [] is_a: GO:0010565 ! regulation of cellular ketone metabolic process is_a: GO:0033238 ! regulation of amine metabolic process -is_a: GO:0051171 ! regulation of nitrogen compound metabolic process is_a: GO:0080090 ! regulation of primary metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006520 ! amino acid metabolic process @@ -48957,7 +49697,7 @@ namespace: biological_process def: "The chemical reactions and pathways involving compounds derived from amino acids, organic acids containing one or more amino substituents." [GOC:ai] subset: goslim_drosophila subset: goslim_generic -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "amino acid derivative metabolic process" EXACT [] synonym: "cellular amino acid derivative metabolic process" EXACT [] synonym: "cellular amino acid derivative metabolism" EXACT [] @@ -49078,8 +49818,8 @@ subset: goslim_mouse subset: goslim_pir subset: goslim_plant subset: goslim_pombe +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset synonym: "lipid metabolism" EXACT [] xref: Wikipedia:Lipid_metabolism is_a: GO:0044238 ! primary metabolic process @@ -49374,6 +50114,7 @@ id: GO:0006807 name: nitrogen compound metabolic process namespace: biological_process def: "The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen." [GOC:jl, ISBN:0198506732] +subset: gocheck_do_not_annotate subset: goslim_metagenomics subset: goslim_pir synonym: "nitrogen compound metabolism" EXACT [] @@ -49381,21 +50122,7 @@ is_a: GO:0008152 ! metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:51143 relationship: has_primary_input_or_output CHEBI:51143 - -[Term] -id: GO:0006809 -name: nitric oxide biosynthetic process -namespace: biological_process -def: "The chemical reactions and pathways resulting in the formation of nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water." [GOC:ai] -synonym: "nitric oxide anabolism" EXACT [] -synonym: "nitric oxide biosynthesis" EXACT [] -synonym: "nitric oxide formation" EXACT [] -synonym: "nitric oxide synthesis" EXACT [] -is_a: GO:0044271 ! cellular nitrogen compound biosynthetic process -is_a: GO:0046209 ! nitric oxide metabolic process -intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:16480 -relationship: has_primary_output CHEBI:16480 +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI [Term] id: GO:0006810 @@ -49412,7 +50139,7 @@ subset: goslim_chembl subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "single-organism transport" RELATED [] is_a: GO:0051234 ! establishment of localization property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20292" xsd:anyURI @@ -49631,7 +50358,7 @@ namespace: biological_process alt_id: GO:0032779 def: "The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell." [GOC:mah] subset: goslim_generic -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "copper-induced intracellular protein transport" RELATED [GOC:al] is_a: GO:0015031 ! protein transport is_a: GO:0046907 ! intracellular transport @@ -50074,8 +50801,8 @@ subset: goslim_candida subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset synonym: "cytoskeletal organization and biogenesis" RELATED [GOC:mah] synonym: "cytoskeletal regulator activity" RELATED [] synonym: "cytoskeleton organisation" EXACT [] @@ -50323,8 +51050,8 @@ subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_pir +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset synonym: "chromosome division" EXACT [] synonym: "chromosome transmission" RELATED [] xref: Wikipedia:Chromosome_segregation @@ -50491,7 +51218,7 @@ subset: goslim_generic subset: goslim_metagenomics subset: goslim_pir subset: goslim_pombe -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "cell adhesion molecule activity" RELATED [] synonym: "single organism cell adhesion" RELATED [] xref: Wikipedia:Cell_adhesion @@ -50540,7 +51267,7 @@ def: "Any cellular process that results in the specification, formation or maint subset: goslim_drosophila subset: goslim_generic subset: goslim_pombe -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "cell polarity" RELATED [GOC:mah, GOC:vw] synonym: "establishment and/or maintenance of cell polarity" RELATED [] synonym: "establishment and/or maintenance of cell polarization" RELATED [] @@ -50984,39 +51711,6 @@ intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0000579 ! border follicle cell relationship: results_in_movement_of CL:0000579 ! border follicle cell -[Term] -id: GO:0007300 -name: ovarian nurse cell to oocyte transport -namespace: biological_process -def: "Transfer of constituents synthesized in the ovarian nurse cells to the oocyte, through the ring canals, as the egg chamber is growing. An example of this is found in Drosophila melanogaster." [GOC:mtg_sensu, ISBN:0879694238] -synonym: "nurse cell to oocyte transport" BROAD [] -is_a: GO:0006810 ! transport -is_a: GO:0022414 ! reproductive process -intersection_of: GO:0006810 ! transport -intersection_of: has_target_end_location CL:0000023 ! oocyte -intersection_of: has_target_start_location CL:0000026 ! invertebrate nurse cell -intersection_of: results_in_transport_along GO:0045172 ! germline ring canal -relationship: has_target_end_location CL:0000023 ! oocyte -relationship: has_target_start_location CL:0000026 ! invertebrate nurse cell -relationship: in_taxon NCBITaxon:50557 {all_only="true"} ! Insecta -relationship: only_in_taxon NCBITaxon:50557 ! Insecta -relationship: part_of GO:0048477 ! oogenesis -relationship: results_in_transport_along GO:0045172 ! germline ring canal - -[Term] -id: GO:0007303 -name: cytoplasmic transport, nurse cell to oocyte -namespace: biological_process -def: "The directed movement of cytoplasmic constituents synthesized in the nurse cells to the oocyte." [ISBN:0879694238] -is_a: GO:0016482 ! cytosolic transport -is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism -intersection_of: GO:0016482 ! cytosolic transport -intersection_of: has_target_end_location CL:0000023 ! oocyte -intersection_of: has_target_start_location CL:0000026 ! invertebrate nurse cell -relationship: has_target_end_location CL:0000023 ! oocyte -relationship: has_target_start_location CL:0000026 ! invertebrate nurse cell -relationship: part_of GO:0007300 ! ovarian nurse cell to oocyte transport - [Term] id: GO:0007308 name: oocyte construction @@ -51766,9 +52460,9 @@ xref: Wikipedia:Coagulation is_a: GO:0007599 ! hemostasis is_a: GO:0050817 ! coagulation intersection_of: GO:0050817 ! coagulation -intersection_of: has_primary_output UBERON:0010210 ! blood clot -relationship: has_primary_output UBERON:0010210 ! blood clot +intersection_of: results_in_assembly_of UBERON:0010210 ! blood clot relationship: part_of GO:0042060 ! wound healing +relationship: results_in_assembly_of UBERON:0010210 ! blood clot [Term] id: GO:0007599 @@ -52030,8 +52724,8 @@ subset: goslim_drosophila subset: goslim_flybase_ribbon subset: goslim_generic subset: goslim_mouse +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset is_a: GO:0005515 ! protein binding [Term] @@ -52241,7 +52935,7 @@ id: GO:0008219 name: cell death namespace: biological_process def: "Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538)." [GOC:mah, GOC:mtg_apoptosis, PMID:25236395] -comment: This term should not be used for direct annotation, it is currently kept in GO as a placeholder for describing cell death phenotypes in uPHENO. When information is provided on a programmed cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'). Unintentional cell death, i.e. cell death caused by injury, ageing, or cell phenotypes observed as a result of a pathological mutation in an essential gene should NOT be annotated using GO terms. +comment: This term should not be used for direct annotation, it is currently kept in GO as a placeholder for describing cell death phenotypes in uPHENO. When information is provided on a programmed cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'). Unintentional cell death, i.e. cell death caused by injury, ageing, or cell phenotypes observed as a result of a pathological mutation in an essential gene should NOT be annotated using GO terms. subset: gocheck_do_not_annotate synonym: "accidental cell death" RELATED [] synonym: "necrosis" RELATED [] @@ -52355,8 +53049,8 @@ subset: goslim_generic subset: goslim_mouse subset: goslim_pir subset: goslim_plant +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset is_a: GO:0005488 ! binding intersection_of: GO:0005488 ! binding intersection_of: has_primary_input CHEBI:18059 @@ -52719,24 +53413,6 @@ relationship: has_primary_input CHEBI:18133 created_by: bf creation_date: 2010-04-08T10:27:23Z -[Term] -id: GO:0008652 -name: amino acid biosynthetic process -namespace: biological_process -def: "The chemical reactions and pathways resulting in the formation of amino acids, organic acids containing one or more amino substituents." [ISBN:0198506732] -synonym: "amino acid anabolism" EXACT [] -synonym: "amino acid biosynthesis" EXACT [] -synonym: "amino acid formation" EXACT [] -synonym: "amino acid synthesis" EXACT [] -synonym: "cellular amino acid biosynthetic process" EXACT [] -xref: Wikipedia:Amino_acid_synthesis -is_a: GO:0006520 ! amino acid metabolic process -is_a: GO:0009058 ! biosynthetic process -intersection_of: GO:0009058 ! biosynthetic process -intersection_of: has_primary_output CHEBI:37022 -relationship: has_primary_output CHEBI:37022 -property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/17904" xsd:anyURI - [Term] id: GO:0009056 name: catabolic process @@ -52821,22 +53497,6 @@ relationship: has_primary_output CHEBI:33694 property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/15249" xsd:anyURI property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25418" xsd:anyURI -[Term] -id: GO:0009063 -name: amino acid catabolic process -namespace: biological_process -def: "The chemical reactions and pathways resulting in the breakdown of amino acids, organic acids containing one or more amino substituents." [GOC:ai] -synonym: "amino acid breakdown" EXACT [] -synonym: "amino acid catabolism" EXACT [] -synonym: "amino acid degradation" EXACT [] -synonym: "cellular amino acid catabolic process" EXACT [] -is_a: GO:0006520 ! amino acid metabolic process -is_a: GO:0009056 ! catabolic process -intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:37022 -relationship: has_primary_input CHEBI:37022 -property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/17904" xsd:anyURI - [Term] id: GO:0009064 name: glutamine family amino acid metabolic process @@ -55627,7 +56287,7 @@ subset: goslim_drosophila subset: goslim_generic subset: goslim_mouse subset: goslim_plant -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "caspase-independent apoptosis" RELATED [] synonym: "caspase-independent cell death" NARROW [] synonym: "non-apoptotic programmed cell death" NARROW [] @@ -57598,7 +58258,7 @@ subset: goslim_generic subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant -subset: prokaryote_subset +subset: goslim_prokaryote xref: Wikipedia:Photosynthesis is_a: GO:0044237 ! cellular metabolic process relationship: never_in_taxon NCBITaxon:33208 ! Metazoa @@ -57831,7 +58491,7 @@ subset: goslim_agr subset: goslim_candida subset: goslim_metagenomics subset: goslim_pir -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "RNA metabolism" EXACT [] is_a: GO:0008152 ! metabolic process intersection_of: GO:0008152 ! metabolic process @@ -58024,6 +58684,7 @@ is_a: GO:0046907 ! intracellular transport intersection_of: GO:0006810 ! transport intersection_of: occurs_in GO:0005829 ! cytosol relationship: occurs_in GO:0005829 ! cytosol +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26386" xsd:anyURI [Term] id: GO:0016485 @@ -58133,8 +58794,8 @@ subset: goslim_metagenomics subset: goslim_mouse subset: goslim_pir subset: goslim_plant +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset xref: EC:2.-.-.- xref: Reactome:R-HSA-1483089 "PE is converted to PS by PTDSS2" xref: Reactome:R-HSA-1483186 "PC is converted to PS by PTDSS1" @@ -58175,8 +58836,8 @@ subset: goslim_metagenomics subset: goslim_mouse subset: goslim_pir subset: goslim_plant +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset xref: EC:3.-.-.- xref: Reactome:R-HSA-1236938 "Partial proteolysis of antigen in phagolysosomes" xref: Reactome:R-HSA-2029475 "Production of AA by iPLA2 upon FCGR activation" @@ -58704,7 +59365,7 @@ synonym: "calcium signaling" EXACT [] synonym: "calcium signalling" EXACT [] synonym: "calcium-mediated signalling" EXACT [] xref: Wikipedia:Calcium_signaling -is_a: GO:0019932 ! second-messenger-mediated signaling +is_a: GO:0141124 ! intracellular signaling cassette [Term] id: GO:0019724 @@ -58746,7 +59407,7 @@ alt_id: GO:0006960 alt_id: GO:0019735 def: "An immune response against microbes mediated through a body fluid. Examples of this process are seen in the antimicrobial humoral response of Drosophila melanogaster and Mus musculus." [GOC:go_curators, GOC:mtg_sensu] is_a: GO:0006959 ! humoral immune response -is_a: GO:0098542 ! defense response to other organism +is_a: GO:0140546 ! defense response to symbiont [Term] id: GO:0019748 @@ -58763,16 +59424,6 @@ synonym: "secondary metabolite metabolism" EXACT [] xref: Wikipedia:Secondary_metabolism is_a: GO:0008152 ! metabolic process -[Term] -id: GO:0019749 -name: cytoskeleton-dependent cytoplasmic transport, nurse cell to oocyte -namespace: biological_process -def: "The directed movement of substances along cytoskeletal elements, such as microfilaments or microtubules, from a nurse cell to an oocyte." [GOC:ai] -is_a: GO:0007303 ! cytoplasmic transport, nurse cell to oocyte -is_a: GO:0030705 ! cytoskeleton-dependent intracellular transport -intersection_of: GO:0007303 ! cytoplasmic transport, nurse cell to oocyte -intersection_of: GO:0030705 ! cytoskeleton-dependent intracellular transport - [Term] id: GO:0019752 name: carboxylic acid metabolic process @@ -58874,19 +59525,6 @@ def: "The process in which an antigen-presenting cell expresses antigen (peptide synonym: "antigen presentation, exogenous antigen" EXACT [] is_a: GO:0019882 ! antigen processing and presentation -[Term] -id: GO:0019932 -name: second-messenger-mediated signaling -namespace: biological_process -def: "Any intracellular signal transduction in which the signal is passed on within the cell via a second messenger; a small molecule or ion that can be quickly generated or released from intracellular stores, and can diffuse within the cell. Second-messenger signaling includes production or release of the second messenger, and effectors downstream of the second messenger that further transmit the signal within the cell." [GOC:signaling, ISBN:0815316194, PMID:15221855, Wikipedia:Second_messenger_system] -synonym: "second messenger mediated signaling" EXACT [] -synonym: "second messenger mediated signalling" EXACT [] -synonym: "second messenger-mediated signaling" EXACT [] -synonym: "second messenger-mediated signalling" EXACT [] -synonym: "second-messenger-mediated signal transduction" EXACT [GOC:signaling] -synonym: "second-messenger-mediated signalling" EXACT [] -is_a: GO:0035556 ! intracellular signal transduction - [Term] id: GO:0019953 name: sexual reproduction @@ -61842,8 +62480,8 @@ subset: goslim_flybase_ribbon subset: goslim_generic subset: goslim_mouse subset: goslim_pombe +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset synonym: "biological signaling" EXACT [] synonym: "signaling process" EXACT [] synonym: "signalling" EXACT [] @@ -61953,7 +62591,7 @@ id: GO:0030030 name: cell projection organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon." [GOC:jl, GOC:mah, http://www.cogsci.princeton.edu/~wn/] -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "cell projection organisation" EXACT [] synonym: "cell projection organization and biogenesis" RELATED [GOC:mah] synonym: "cell surface structure organization and biogenesis" RELATED [GOC:mah] @@ -62223,7 +62861,7 @@ subset: goslim_candida subset: goslim_drosophila subset: goslim_generic subset: goslim_pombe -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "cellular protein breakdown" EXACT [] synonym: "cellular protein catabolic process" EXACT [] synonym: "cellular protein catabolism" EXACT [] @@ -62311,27 +62949,6 @@ intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000236 ! B cell relationship: results_in_acquisition_of_features_of CL:0000236 ! B cell -[Term] -id: GO:0030184 -name: nitric oxide transmembrane transporter activity -namespace: molecular_function -def: "Enables the transfer of nitric oxide, nitrogen monoxide, from one side of a membrane to the other." [GOC:mah] -is_a: GO:0022857 ! transmembrane transporter activity -intersection_of: GO:0022857 ! transmembrane transporter activity -intersection_of: has_primary_input CHEBI:16480 -relationship: has_primary_input CHEBI:16480 -relationship: part_of GO:0030185 ! nitric oxide transport - -[Term] -id: GO:0030185 -name: nitric oxide transport -namespace: biological_process -def: "The directed movement of nitric oxide, nitrogen monoxide, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] -is_a: GO:0006810 ! transport -intersection_of: GO:0006810 ! transport -intersection_of: has_primary_input CHEBI:16480 -relationship: has_primary_input CHEBI:16480 - [Term] id: GO:0030186 name: melatonin metabolic process @@ -63809,7 +64426,7 @@ subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_pir -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "matrisome" NARROW [] synonym: "proteinaceous extracellular matrix" EXACT [] xref: NIF_Subcellular:nlx_subcell_20090513 @@ -69859,20 +70476,6 @@ synonym: "granzyme B localization in T-cell secretory granule" EXACT [] synonym: "granzyme B localization in T-lymphocyte secretory granule" EXACT [] is_a: GO:0033375 ! protease localization to T cell secretory granule -[Term] -id: GO:0033484 -name: intracellular nitric oxide homeostasis -namespace: biological_process -def: "A homeostatic process involved in the maintenance of a steady state level of nitric oxide within a cell." [GOC:mah] -synonym: "cellular nitric oxide homeostasis" EXACT [] -synonym: "nitric oxide homeostasis" BROAD [] -synonym: "NO homeostasis" BROAD [] -is_a: GO:0055082 ! intracellular chemical homeostasis -intersection_of: GO:0055082 ! intracellular chemical homeostasis -intersection_of: regulates_levels_of CHEBI:16480 -relationship: regulates_levels_of CHEBI:16480 -property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24224" xsd:anyURI - [Term] id: GO:0033500 name: carbohydrate homeostasis @@ -70765,10 +71368,12 @@ id: GO:0034641 name: cellular nitrogen compound metabolic process namespace: biological_process def: "The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells." [GOC:mah] +subset: gocheck_do_not_annotate subset: goslim_chembl synonym: "cellular nitrogen compound metabolism" EXACT [] is_a: GO:0006807 ! nitrogen compound metabolic process is_a: GO:0044237 ! cellular metabolic process +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI [Term] id: GO:0034654 @@ -71843,13 +72448,9 @@ alt_id: GO:0023013 alt_id: GO:0023034 def: "The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell." [GOC:bf, GOC:jl, GOC:signaling, ISBN:3527303782] subset: goslim_drosophila -synonym: "intracellular protein kinase cascade" NARROW [GOC:signaling] synonym: "intracellular signal transduction pathway" NARROW [] synonym: "intracellular signaling cascade" RELATED [GOC:signaling] -synonym: "intracellular signaling chain" EXACT [ISBN:3527303782] synonym: "intracellular signaling pathway" RELATED [] -synonym: "protein kinase cascade" NARROW [GOC:signaling] -synonym: "signal transduction via intracellular signaling cascade" RELATED [] synonym: "signal transmission via intracellular cascade" NARROW [] is_a: GO:0007165 ! signal transduction intersection_of: GO:0007165 ! signal transduction @@ -73264,7 +73865,7 @@ subset: goslim_candida subset: goslim_chembl subset: goslim_pir subset: goslim_plant -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "cellular protein modification process" EXACT [] synonym: "process resulting in protein modification" EXACT [] synonym: "protein modification" EXACT [GOC:bf] @@ -74671,7 +75272,7 @@ subset: goslim_drosophila subset: goslim_generic subset: goslim_pir subset: goslim_pombe -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "ribosome biogenesis and assembly" EXACT [] is_a: GO:0022613 ! ribonucleoprotein complex biogenesis @@ -76088,7 +76689,7 @@ subset: goslim_agr subset: goslim_flybase_ribbon subset: goslim_mouse subset: goslim_pir -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "cell process" BROAD [] synonym: "cellular process" BROAD [] synonym: "cellular projection" EXACT [] @@ -76338,7 +76939,7 @@ name: extracellular structure organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures in the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane, and also covers the host cell environment outside an intracellular parasite." [GOC:ai, GOC:dph, GOC:jl, GOC:mah] subset: goslim_pir -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "extracellular structure organisation" EXACT [] synonym: "extracellular structure organization and biogenesis" EXACT [GOC:dph, GOC:jl, GOC:mah] is_a: GO:0016043 ! cellular component organization @@ -76346,18 +76947,6 @@ intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0005576 ! extracellular region relationship: results_in_organization_of GO:0005576 ! extracellular region -[Term] -id: GO:0043063 -name: intercellular bridge organization -namespace: biological_process -def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the intracellular bridge. An intracellular bridge is a direct link between the cytoplasms of sister cells that allows cells to communicate with one another." [GOC:jid] -synonym: "intercellular bridge organisation" EXACT [] -synonym: "intercellular bridge organization and biogenesis" RELATED [GOC:mah] -is_a: GO:0043062 ! extracellular structure organization -intersection_of: GO:0016043 ! cellular component organization -intersection_of: results_in_organization_of GO:0045171 ! intercellular bridge -relationship: results_in_organization_of GO:0045171 ! intercellular bridge - [Term] id: GO:0043065 name: positive regulation of apoptotic process @@ -76608,6 +77197,7 @@ alt_id: GO:0034960 alt_id: GO:0043283 alt_id: GO:0044259 def: "The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:mah] +subset: gocheck_do_not_annotate subset: goslim_pir synonym: "biopolymer metabolic process" EXACT [GOC:mtg_chebi_dec09] synonym: "macromolecule metabolism" EXACT [] @@ -76617,6 +77207,7 @@ is_a: GO:0008152 ! metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:33694 relationship: has_primary_input_or_output CHEBI:33694 +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI [Term] id: GO:0043171 @@ -76735,7 +77326,7 @@ def: "Organized structure of distinctive morphology and function. Includes the n subset: goslim_chembl subset: goslim_generic subset: goslim_pir -subset: prokaryote_subset +subset: goslim_prokaryote xref: NIF_Subcellular:sao1539965131 xref: Wikipedia:Organelle is_a: GO:0110165 ! cellular anatomical entity @@ -78697,9 +79288,11 @@ id: GO:0044238 name: primary metabolic process namespace: biological_process def: "The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism." [GOC:go_curators, http://www.metacyc.org] +subset: gocheck_do_not_annotate subset: goslim_pir synonym: "primary metabolism" EXACT [] is_a: GO:0008152 ! metabolic process +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI [Term] id: GO:0044242 @@ -78814,7 +79407,7 @@ name: small molecule biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of small molecules, any low molecular weight, monomeric, non-encoded molecule." [GOC:curators, GOC:pde, GOC:vw] comment: Small molecules in GO include monosaccharides but exclude disaccharides and polysaccharides. -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "small molecule biosynthesis" EXACT [] is_a: GO:0009058 ! biosynthetic process is_a: GO:0044281 ! small molecule metabolic process @@ -79075,27 +79668,6 @@ namespace: cellular_component def: "An intracellular membrane-bounded particle found in fungi and containing chitin synthase; it synthesizes chitin microfibrils. Chitin synthase activity exists in chitosomes and they are proposed to act as a reservoir for regulated transport of chitin synthase enzymes to the division septum." [ISBN:0198506732, PMID:8970154] is_a: GO:0031410 ! cytoplasmic vesicle -[Term] -id: GO:0045019 -name: negative regulation of nitric oxide biosynthetic process -namespace: biological_process -def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide." [GOC:go_curators] -synonym: "down regulation of nitric oxide biosynthetic process" EXACT [] -synonym: "down-regulation of nitric oxide biosynthetic process" EXACT [] -synonym: "downregulation of nitric oxide biosynthetic process" EXACT [] -synonym: "inhibition of nitric oxide biosynthetic process" NARROW [] -synonym: "negative regulation of nitric oxide anabolism" EXACT [] -synonym: "negative regulation of nitric oxide biosynthesis" EXACT [] -synonym: "negative regulation of nitric oxide formation" EXACT [] -synonym: "negative regulation of nitric oxide synthesis" EXACT [] -is_a: GO:0031327 ! negative regulation of cellular biosynthetic process -is_a: GO:0045428 ! regulation of nitric oxide biosynthetic process -is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process -is_a: GO:1904406 ! negative regulation of nitric oxide metabolic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: negatively_regulates GO:0006809 ! nitric oxide biosynthetic process -relationship: negatively_regulates GO:0006809 ! nitric oxide biosynthetic process - [Term] id: GO:0045026 name: plasma membrane fusion @@ -79213,7 +79785,7 @@ synonym: "innate immunity" EXACT [GOC:pg] synonym: "nonspecific immune response" EXACT [] xref: Wikipedia:Innate_immune_system is_a: GO:0006955 ! immune response -is_a: GO:0098542 ! defense response to other organism +is_a: GO:0140546 ! defense response to symbiont [Term] id: GO:0045088 @@ -79383,22 +79955,6 @@ intersection_of: GO:0007267 ! cell-cell signaling intersection_of: part_of GO:0045165 ! cell fate commitment relationship: part_of GO:0045165 ! cell fate commitment -[Term] -id: GO:0045171 -name: intercellular bridge -namespace: cellular_component -def: "A direct connection between the cytoplasm of two cells that is formed following the completion of cleavage furrow ingression during cell division. They are usually present only briefly prior to completion of cytokinesis. However, in some cases, such as the bridges between germ cells during their development, they become stabilised." [PMID:9635420] -is_a: GO:0110165 ! cellular anatomical entity - -[Term] -id: GO:0045172 -name: germline ring canal -namespace: cellular_component -def: "Germline specific intercellular bridge. During cyst formation in insects, ring canals interconnect the cells of the cyst, facilitating the passage of cytoplasmic components between cells." [GOC:mtg_sensu, PMID:9635420, PMID:9655801] -is_a: GO:0045171 ! intercellular bridge -relationship: in_taxon NCBITaxon:6656 {all_only="true"} ! Arthropoda -relationship: only_in_taxon NCBITaxon:6656 ! Arthropoda - [Term] id: GO:0045184 name: establishment of protein localization @@ -79707,44 +80263,6 @@ relationship: has_primary_input CL:0000738 ! leukocyte relationship: in_taxon NCBITaxon:7742 {all_only="true"} ! Vertebrata relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata -[Term] -id: GO:0045428 -name: regulation of nitric oxide biosynthetic process -namespace: biological_process -def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide." [GOC:go_curators] -synonym: "regulation of nitric oxide anabolism" EXACT [] -synonym: "regulation of nitric oxide biosynthesis" EXACT [] -synonym: "regulation of nitric oxide formation" EXACT [] -synonym: "regulation of nitric oxide synthesis" EXACT [] -is_a: GO:0031326 ! regulation of cellular biosynthetic process -is_a: GO:0051171 ! regulation of nitrogen compound metabolic process -is_a: GO:0080164 ! regulation of nitric oxide metabolic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: regulates GO:0006809 ! nitric oxide biosynthetic process -relationship: regulates GO:0006809 ! nitric oxide biosynthetic process - -[Term] -id: GO:0045429 -name: positive regulation of nitric oxide biosynthetic process -namespace: biological_process -def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide." [GOC:go_curators] -synonym: "activation of nitric oxide biosynthetic process" NARROW [] -synonym: "positive regulation of nitric oxide anabolism" EXACT [] -synonym: "positive regulation of nitric oxide biosynthesis" EXACT [] -synonym: "positive regulation of nitric oxide formation" EXACT [] -synonym: "positive regulation of nitric oxide synthesis" EXACT [] -synonym: "stimulation of nitric oxide biosynthetic process" NARROW [] -synonym: "up regulation of nitric oxide biosynthetic process" EXACT [] -synonym: "up-regulation of nitric oxide biosynthetic process" EXACT [] -synonym: "upregulation of nitric oxide biosynthetic process" EXACT [] -is_a: GO:0031328 ! positive regulation of cellular biosynthetic process -is_a: GO:0045428 ! regulation of nitric oxide biosynthetic process -is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process -is_a: GO:1904407 ! positive regulation of nitric oxide metabolic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: positively_regulates GO:0006809 ! nitric oxide biosynthetic process -relationship: positively_regulates GO:0006809 ! nitric oxide biosynthetic process - [Term] id: GO:0045443 name: juvenile hormone secretion @@ -81971,10 +82489,7 @@ synonym: "downregulation of amino acid metabolic process" EXACT [] synonym: "inhibition of amino acid metabolic process" NARROW [] synonym: "negative regulation of amino acid metabolism" EXACT [] is_a: GO:0006521 ! regulation of cellular amino acid metabolic process -is_a: GO:0031324 ! negative regulation of cellular metabolic process is_a: GO:0033239 ! negative regulation of amine metabolic process -is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process -is_a: GO:0062014 ! negative regulation of small molecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006520 ! amino acid metabolic process relationship: negatively_regulates GO:0006520 ! amino acid metabolic process @@ -81992,10 +82507,7 @@ synonym: "up regulation of amino acid metabolic process" EXACT [] synonym: "up-regulation of amino acid metabolic process" EXACT [] synonym: "upregulation of amino acid metabolic process" EXACT [] is_a: GO:0006521 ! regulation of cellular amino acid metabolic process -is_a: GO:0031325 ! positive regulation of cellular metabolic process is_a: GO:0033240 ! positive regulation of amine metabolic process -is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process -is_a: GO:0062013 ! positive regulation of small molecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006520 ! amino acid metabolic process relationship: positively_regulates GO:0006520 ! amino acid metabolic process @@ -83556,31 +84068,6 @@ intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:33853 relationship: has_primary_output CHEBI:33853 -[Term] -id: GO:0046209 -name: nitric oxide metabolic process -namespace: biological_process -def: "The chemical reactions and pathways involving nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water." [GOC:ai] -synonym: "nitric oxide metabolism" EXACT [] -is_a: GO:0008152 ! metabolic process -intersection_of: GO:0008152 ! metabolic process -intersection_of: has_primary_input_or_output CHEBI:16480 -relationship: has_primary_input_or_output CHEBI:16480 - -[Term] -id: GO:0046210 -name: nitric oxide catabolic process -namespace: biological_process -def: "The chemical reactions and pathways resulting in the breakdown of nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water." [GOC:ai] -synonym: "nitric oxide breakdown" EXACT [] -synonym: "nitric oxide catabolism" EXACT [] -synonym: "nitric oxide degradation" EXACT [] -is_a: GO:0044270 ! cellular nitrogen compound catabolic process -is_a: GO:0046209 ! nitric oxide metabolic process -intersection_of: GO:0009056 ! catabolic process -intersection_of: has_primary_input CHEBI:16480 -relationship: has_primary_input CHEBI:16480 - [Term] id: GO:0046344 name: ecdysteroid catabolic process @@ -84613,10 +85100,11 @@ name: hydroxyapatite binding namespace: molecular_function def: "Binding to hydroxyapatite, the calcium phosphate mineral of formula Ca10(PO4)6(OH)2 found both in rocks of nonorganic origin and as a component of bone and dentin." [PMID:2438276] synonym: "hydroxylapatite binding" EXACT [GOC:vk] -is_a: GO:0005488 ! binding +is_a: GO:0036094 ! small molecule binding intersection_of: GO:0005488 ! binding intersection_of: has_primary_input CHEBI:52255 relationship: has_primary_input CHEBI:52255 +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21211" xsd:anyURI [Term] id: GO:0046849 @@ -86114,10 +86602,12 @@ id: GO:0048588 name: developmental cell growth namespace: biological_process def: "The growth of a cell, where growth contributes to the progression of the cell over time from one condition to another." [GOC:go_curators, GOC:isa_complete] +subset: gocheck_do_not_annotate synonym: "developmental growth of a unicellular organism" EXACT [] is_a: GO:0016049 ! cell growth is_a: GO:0048589 ! developmental growth relationship: part_of GO:0048468 ! cell development +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI [Term] id: GO:0048589 @@ -87424,6 +87914,7 @@ id: GO:0048856 name: anatomical structure development namespace: biological_process def: "The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome." [GO_REF:0000021] +subset: gocheck_do_not_annotate subset: goslim_chembl subset: goslim_generic subset: goslim_plant @@ -87432,6 +87923,7 @@ is_a: GO:0032502 ! developmental process intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of UBERON:0000061 ! anatomical structure relationship: results_in_development_of UBERON:0000061 ! anatomical structure +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI [Term] id: GO:0048857 @@ -87514,7 +88006,7 @@ def: "Any process involved in the controlled self-propelled movement of a cell t subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "cell locomotion" EXACT [] synonym: "cell movement" RELATED [] synonym: "movement of a cell" EXACT [] @@ -89282,7 +89774,7 @@ subset: goslim_agr subset: goslim_flybase_ribbon subset: goslim_mouse subset: goslim_pir -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "physiological response to stimulus" EXACT [] is_a: GO:0008150 ! biological_process @@ -91586,10 +92078,11 @@ name: epinephrine binding namespace: molecular_function def: "Binding to epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine." [GOC:ai] synonym: "adrenaline binding" EXACT [] -is_a: GO:0005488 ! binding +is_a: GO:0042562 ! hormone binding intersection_of: GO:0005488 ! binding intersection_of: has_primary_input CHEBI:33568 relationship: has_primary_input CHEBI:33568 +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21211" xsd:anyURI [Term] id: GO:0051380 @@ -92093,8 +92586,8 @@ subset: goslim_drosophila subset: goslim_generic subset: goslim_pir subset: goslim_pombe +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset is_a: GO:0019538 ! protein metabolic process relationship: part_of GO:0010467 ! gene expression @@ -94327,7 +94820,7 @@ def: "A compound molecular function in which an effector function is controlled subset: gocheck_do_not_manually_annotate subset: goslim_generic subset: goslim_pir -subset: prokaryote_subset +subset: goslim_prokaryote is_a: GO:0003674 ! molecular_function [Term] @@ -94339,7 +94832,7 @@ def: "The binding activity of a molecule that brings together two or more molecu subset: goslim_drosophila subset: goslim_generic subset: goslim_pir -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "binding, bridging" EXACT [] synonym: "protein complex scaffold activity" RELATED [] synonym: "protein-containing complex scaffold activity" RELATED [] @@ -98673,7 +99166,7 @@ subset: goslim_drosophila subset: goslim_generic subset: goslim_pir subset: goslim_pombe -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "cellular membrane organisation" EXACT [] synonym: "cellular membrane organization" EXACT [] synonym: "membrane organisation" EXACT [GOC:mah] @@ -102277,7 +102770,7 @@ subset: goslim_generic subset: goslim_metagenomics subset: goslim_pir subset: goslim_pombe -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "cellular macromolecule complex assembly" RELATED [] synonym: "cellular protein complex assembly" EXACT [] synonym: "cellular protein-containing complex assembly" RELATED [] @@ -103332,6 +103825,16 @@ intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0000226 ! microtubule cytoskeleton organization relationship: regulates GO:0000226 ! microtubule cytoskeleton organization +[Term] +id: GO:0070509 +name: calcium ion import +namespace: biological_process +def: "The directed movement of calcium ions into a cell or organelle." [GOC:mah] +synonym: "calcium ion uptake" EXACT [GOC:mah] +synonym: "transmembrane calcium influx" RELATED [GOC:tb] +is_a: GO:0006816 ! calcium ion transport +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23015" xsd:anyURI + [Term] id: GO:0070560 name: protein secretion by platelet @@ -103883,16 +104386,6 @@ intersection_of: has_primary_input CHEBI:33709 created_by: mah creation_date: 2009-12-03T02:08:11Z -[Term] -id: GO:0071241 -name: cellular response to inorganic substance -namespace: biological_process -def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus." [GOC:mah] -is_a: GO:0010035 ! response to inorganic substance -is_a: GO:0070887 ! cellular response to chemical stimulus -created_by: mah -creation_date: 2009-12-03T02:35:49Z - [Term] id: GO:0071242 name: cellular response to ammonium ion @@ -104572,6 +105065,7 @@ id: GO:0071704 name: organic substance metabolic process namespace: biological_process def: "The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon." [GOC:mah] +subset: gocheck_do_not_annotate synonym: "organic molecular entity metabolic process" EXACT [] synonym: "organic molecular entity metabolism" EXACT [] synonym: "organic substance metabolism" EXACT [] @@ -104579,6 +105073,7 @@ is_a: GO:0008152 ! metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:50860 relationship: has_primary_input_or_output CHEBI:50860 +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI created_by: mah creation_date: 2010-03-08T03:32:18Z @@ -104659,30 +105154,6 @@ relationship: results_in_organization_of GO:0005604 ! basement membrane created_by: mah creation_date: 2010-03-10T11:57:10Z -[Term] -id: GO:0071731 -name: response to nitric oxide -namespace: biological_process -def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitric oxide stimulus." [GOC:mah, GOC:yaf] -is_a: GO:0050896 ! response to stimulus -intersection_of: GO:0050896 ! response to stimulus -intersection_of: has_primary_input CHEBI:16480 -relationship: has_primary_input CHEBI:16480 -created_by: mah -creation_date: 2010-03-17T04:03:38Z - -[Term] -id: GO:0071732 -name: cellular response to nitric oxide -namespace: biological_process -def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitric oxide stimulus." [GOC:mah, GOC:yaf] -is_a: GO:0071241 ! cellular response to inorganic substance -is_a: GO:0071731 ! response to nitric oxide -intersection_of: GO:0070887 ! cellular response to chemical stimulus -intersection_of: has_primary_input CHEBI:16480 -created_by: mah -creation_date: 2010-03-17T04:12:52Z - [Term] id: GO:0071735 name: IgG immunoglobulin complex @@ -105112,7 +105583,7 @@ def: "A nitrogen compound metabolic process that contributes to the nitrogen cyc subset: goslim_chembl subset: goslim_generic subset: goslim_pombe -subset: prokaryote_subset +subset: goslim_prokaryote xref: Wikipedia:Nitrogen_cycle is_a: GO:0006807 ! nitrogen compound metabolic process created_by: mah @@ -105122,7 +105593,7 @@ creation_date: 2010-09-30T05:21:03Z id: GO:0071944 name: cell periphery namespace: cellular_component -def: "The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures." [GOC:pdt] +def: "The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures." [GOC:pdt] subset: goslim_flybase_ribbon is_a: GO:0110165 ! cellular anatomical entity created_by: mah @@ -108186,7 +108657,7 @@ id: GO:0072657 name: protein localization to membrane namespace: biological_process def: "A process in which a protein is transported to, or maintained in, a specific location in a membrane." [GOC:mah] -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "protein localisation in membrane" EXACT [GOC:mah] synonym: "protein localization in membrane" EXACT [] is_a: GO:0008104 ! protein localization @@ -108496,18 +108967,6 @@ relationship: regulates GO:0009566 ! fertilization created_by: dhl creation_date: 2010-09-01T03:44:27Z -[Term] -id: GO:0080164 -name: regulation of nitric oxide metabolic process -namespace: biological_process -def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water." [GOC:DHL] -is_a: GO:0019222 ! regulation of metabolic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: regulates GO:0046209 ! nitric oxide metabolic process -relationship: regulates GO:0046209 ! nitric oxide metabolic process -created_by: dhl -creation_date: 2010-09-23T04:02:50Z - [Term] id: GO:0080171 name: lytic vacuole organization @@ -109584,6 +110043,47 @@ relationship: negatively_regulates GO:0030072 ! peptide hormone secretion created_by: tb creation_date: 2010-02-05T02:56:39Z +[Term] +id: GO:0090279 +name: regulation of calcium ion import +namespace: biological_process +def: "Any process that modulates the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle." [GOC:BHF] +synonym: "regulation of transmembrane calcium influx" RELATED [GOC:tb] +is_a: GO:0051924 ! regulation of calcium ion transport +intersection_of: GO:0065007 ! biological regulation +intersection_of: regulates GO:0070509 ! calcium ion import +relationship: regulates GO:0070509 ! calcium ion import +created_by: tb +creation_date: 2010-02-08T05:11:20Z + +[Term] +id: GO:0090280 +name: positive regulation of calcium ion import +namespace: biological_process +def: "Any process that increases the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle." [GOC:BHF] +synonym: "positive regulation of transmembrane calcium influx" RELATED [GOC:tb] +is_a: GO:0051928 ! positive regulation of calcium ion transport +is_a: GO:0090279 ! regulation of calcium ion import +intersection_of: GO:0065007 ! biological regulation +intersection_of: positively_regulates GO:0070509 ! calcium ion import +relationship: positively_regulates GO:0070509 ! calcium ion import +created_by: tb +creation_date: 2010-02-08T05:11:20Z + +[Term] +id: GO:0090281 +name: negative regulation of calcium ion import +namespace: biological_process +def: "Any process that decreases the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle." [GOC:BHF] +synonym: "negative regulation of transmembrane calcium influx" RELATED [GOC:tb] +is_a: GO:0051926 ! negative regulation of calcium ion transport +is_a: GO:0090279 ! regulation of calcium ion import +intersection_of: GO:0065007 ! biological regulation +intersection_of: negatively_regulates GO:0070509 ! calcium ion import +relationship: negatively_regulates GO:0070509 ! calcium ion import +created_by: tb +creation_date: 2010-02-08T05:11:20Z + [Term] id: GO:0090289 name: regulation of osteoclast proliferation @@ -111162,7 +111662,7 @@ namespace: biological_process alt_id: GO:0009814 def: "Reactions triggered in response to the presence of another organism that act to protect the cell or organism from damage caused by that organism." [GOC:dos] subset: goslim_generic -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "defence response incompatible interaction" NARROW [] synonym: "defence response to pathogen, incompatible interaction" NARROW [] synonym: "defense response, incompatible interaction" NARROW [] @@ -111243,7 +111743,7 @@ name: cell adhesion mediator activity namespace: molecular_function def: "The binding by a cell-adhesion protein on a cell surface to an adhesion molecule on another cell surface or an external substrate, to mediate adhesion of the cell to the external substrate or to another cell." [GOC:vw, Wikipedia:Cell_adhesion] subset: goslim_generic -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "cell adhesion molecule" EXACT [] synonym: "protein binding involved in cell adhesion" EXACT [] is_a: GO:0050839 ! cell adhesion molecule binding @@ -111269,10 +111769,11 @@ id: GO:0098633 name: collagen fibril binding namespace: molecular_function def: "Binding to a collagen fibril." [GOC:dos, PMID:21421911] -is_a: GO:0005488 ! binding +is_a: GO:0050840 ! extracellular matrix binding intersection_of: GO:0005488 ! binding intersection_of: has_primary_input GO:0098643 ! banded collagen fibril relationship: has_primary_input GO:0098643 ! banded collagen fibril +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21211" xsd:anyURI [Term] id: GO:0098635 @@ -111473,13 +111974,16 @@ alt_id: GO:1990035 def: "The directed movement of calcium ions from outside of a cell, across the plasma membrane and into the cytosol." [GOC:dos] synonym: "calcium ion import into cell" EXACT [] synonym: "calcium ion uptake into cell" EXACT [GOC:vw] +is_a: GO:0070509 ! calcium ion import is_a: GO:0097553 ! calcium ion transmembrane import into cytosol is_a: GO:0098739 ! import across plasma membrane +is_a: GO:1902656 ! calcium ion import into cytosol intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:29108 intersection_of: has_target_end_location GO:0005829 ! cytosol intersection_of: has_target_start_location GO:0005576 ! extracellular region intersection_of: results_in_transport_across GO:0005886 ! plasma membrane +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24965" xsd:anyURI created_by: mah creation_date: 2013-02-07T13:07:59Z @@ -111619,12 +112123,12 @@ namespace: biological_process def: "The directed movement of some substance from outside of a cell, across the plasma membrane and into the cytosol." [GOC:dos] synonym: "uptake" BROAD [] is_a: GO:0055085 ! transmembrane transport +is_a: GO:0098657 ! import into cell intersection_of: GO:0006810 ! transport intersection_of: has_target_end_location GO:0005829 ! cytosol intersection_of: has_target_start_location GO:0005576 ! extracellular region intersection_of: results_in_transport_across GO:0005886 ! plasma membrane relationship: has_target_end_location GO:0005829 ! cytosol -relationship: has_target_start_location GO:0005576 ! extracellular region relationship: results_in_transport_across GO:0005886 ! plasma membrane [Term] @@ -111658,7 +112162,7 @@ namespace: biological_process def: "Any process that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance." [GOC:dos] subset: goslim_generic subset: goslim_pombe -subset: prokaryote_subset +subset: goslim_prokaryote is_a: GO:0008150 ! biological_process relationship: part_of GO:0009636 ! response to toxic substance @@ -112043,46 +112547,6 @@ intersection_of: has_end_location GO:0098793 ! presynapse intersection_of: has_start_location GO:0098794 ! postsynapse intersection_of: process_has_causal_agent CHEBI:18059 -[Term] -id: GO:0098923 -name: retrograde trans-synaptic signaling by soluble gas -namespace: biological_process -def: "Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by an soluble gas ligand." [GOC:dos] -subset: goslim_synapse -is_a: GO:0098917 ! retrograde trans-synaptic signaling -is_a: GO:0099543 ! trans-synaptic signaling by soluble gas -intersection_of: GO:0099543 ! trans-synaptic signaling by soluble gas -intersection_of: has_end_location GO:0098793 ! presynapse -intersection_of: has_start_location GO:0098794 ! postsynapse - -[Term] -id: GO:0098924 -name: retrograde trans-synaptic signaling by nitric oxide -namespace: biological_process -def: "Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by nitric oxide." [GOC:dos] -subset: goslim_synapse -is_a: GO:0098923 ! retrograde trans-synaptic signaling by soluble gas -is_a: GO:0099548 ! trans-synaptic signaling by nitric oxide -intersection_of: GO:0099537 ! trans-synaptic signaling -intersection_of: has_end_location GO:0098793 ! presynapse -intersection_of: has_start_location GO:0098794 ! postsynapse -intersection_of: process_has_causal_agent CHEBI:16480 - -[Term] -id: GO:0098925 -name: retrograde trans-synaptic signaling by nitric oxide, modulating synaptic transmission -namespace: biological_process -def: "Modulation of synaptic transmission by cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by nitric oxide." [GOC:dos] -comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. -subset: goslim_synapse -is_a: GO:0098924 ! retrograde trans-synaptic signaling by nitric oxide -is_a: GO:0099555 ! trans-synaptic signaling by nitric oxide, modulating synaptic transmission -intersection_of: GO:0099537 ! trans-synaptic signaling -intersection_of: has_end_location GO:0098793 ! presynapse -intersection_of: has_start_location GO:0098794 ! postsynapse -intersection_of: process_has_causal_agent CHEBI:16480 -intersection_of: regulates GO:0007268 ! chemical synaptic transmission - [Term] id: GO:0098926 name: postsynaptic signal transduction @@ -112164,19 +112628,6 @@ intersection_of: results_in_transport_along GO:0005874 ! microtubule relationship: has_target_end_location GO:0098794 ! postsynapse relationship: occurs_in GO:0032839 ! dendrite cytoplasm -[Term] -id: GO:0098940 -name: anterograde trans-synaptic signaling by nitric oxide -namespace: biological_process -def: "Cell-cell signaling from presynapse to postynapse, across the synaptic cleft, mediated by nitric oxide." [GOC:dos] -subset: goslim_synapse -is_a: GO:0098916 ! anterograde trans-synaptic signaling -is_a: GO:0099548 ! trans-synaptic signaling by nitric oxide -intersection_of: GO:0099537 ! trans-synaptic signaling -intersection_of: has_end_location GO:0098794 ! postsynapse -intersection_of: has_start_location GO:0098793 ! presynapse -intersection_of: process_has_causal_agent CHEBI:16480 - [Term] id: GO:0098960 name: postsynaptic neurotransmitter receptor activity @@ -112641,17 +113092,6 @@ intersection_of: part_of GO:0098794 ! postsynapse created_by: dos creation_date: 2017-08-28T15:26:08Z -[Term] -id: GO:0099163 -name: synaptic signaling by nitric oxide -namespace: biological_process -def: "Cell-cell signaling to or from a synapse, mediated by nitric oxide." [GOC:dos, PMID:19038221] -subset: goslim_synapse -is_a: GO:0099536 ! synaptic signaling -intersection_of: GO:0099536 ! synaptic signaling -intersection_of: process_has_causal_agent CHEBI:16480 -relationship: process_has_causal_agent CHEBI:16480 - [Term] id: GO:0099170 name: postsynaptic modulation of chemical synaptic transmission @@ -113049,14 +113489,6 @@ intersection_of: GO:0099537 ! trans-synaptic signaling intersection_of: process_has_causal_agent CHEBI:18059 relationship: process_has_causal_agent CHEBI:18059 -[Term] -id: GO:0099543 -name: trans-synaptic signaling by soluble gas -namespace: biological_process -def: "Cell-cell signaling between presynapse and postsynapse mediated by a soluble gas ligand crossing the synaptic cleft." [GOC:dos] -subset: goslim_synapse -is_a: GO:0099537 ! trans-synaptic signaling - [Term] id: GO:0099546 name: protein catabolic process, modulating synaptic transmission @@ -113087,17 +113519,6 @@ intersection_of: regulates GO:0006412 ! translation intersection_of: regulates GO:0007268 ! chemical synaptic transmission relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa -[Term] -id: GO:0099548 -name: trans-synaptic signaling by nitric oxide -namespace: biological_process -def: "Cell-cell signaling between presynapse and postsynapse mediated by nitric oxide." [GOC:dos] -subset: goslim_synapse -is_a: GO:0099163 ! synaptic signaling by nitric oxide -is_a: GO:0099543 ! trans-synaptic signaling by soluble gas -intersection_of: GO:0099537 ! trans-synaptic signaling -intersection_of: process_has_causal_agent CHEBI:16480 - [Term] id: GO:0099550 name: trans-synaptic signaling, modulating synaptic transmission @@ -113136,29 +113557,6 @@ intersection_of: GO:0099537 ! trans-synaptic signaling intersection_of: process_has_causal_agent CHEBI:18059 intersection_of: regulates GO:0007268 ! chemical synaptic transmission -[Term] -id: GO:0099554 -name: trans-synaptic signaling by soluble gas, modulating synaptic transmission -namespace: biological_process -def: "Cell-cell signaling between presynapse and postsynapse, via the release and reception of gaseous molecules, that modulates the synaptic transmission properties of the synapse." [GOC:dos] -comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. -subset: goslim_synapse -is_a: GO:0099543 ! trans-synaptic signaling by soluble gas -is_a: GO:0099550 ! trans-synaptic signaling, modulating synaptic transmission - -[Term] -id: GO:0099555 -name: trans-synaptic signaling by nitric oxide, modulating synaptic transmission -namespace: biological_process -def: "Cell-cell signaling between presynapse and postsynapse, via the release and reception of nitric oxide molecules, that modulates the synaptic transmission properties of the synapse." [GOC:dos] -comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. -subset: goslim_synapse -is_a: GO:0099548 ! trans-synaptic signaling by nitric oxide -is_a: GO:0099554 ! trans-synaptic signaling by soluble gas, modulating synaptic transmission -intersection_of: GO:0099537 ! trans-synaptic signaling -intersection_of: process_has_causal_agent CHEBI:16480 -intersection_of: regulates GO:0007268 ! chemical synaptic transmission - [Term] id: GO:0099565 name: chemical synaptic transmission, postsynaptic @@ -114089,6 +114487,7 @@ is_a: CARO:0000000 is_a: GO:0005575 ! cellular_component is_a: UBERON:0000061 ! anatomical structure property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24200" xsd:anyURI +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI created_by: kmv creation_date: 2019-08-12T18:01:37Z @@ -114698,7 +115097,7 @@ name: catalytic activity, acting on a protein namespace: molecular_function def: "Catalytic activity that acts to modify a protein." [GOC:molecular_function_refactoring, GOC:pdt] subset: goslim_generic -subset: prokaryote_subset +subset: goslim_prokaryote is_a: GO:0003824 ! catalytic activity intersection_of: GO:0003824 ! catalytic activity intersection_of: has_primary_input PR:000000001 ! protein @@ -114713,7 +115112,7 @@ name: catalytic activity, acting on DNA namespace: molecular_function def: "Catalytic activity that acts to modify DNA." [GOC:molecular_function_refactoring, GOC:pdt] subset: goslim_generic -subset: prokaryote_subset +subset: goslim_prokaryote is_a: GO:0003824 ! catalytic activity intersection_of: GO:0003824 ! catalytic activity intersection_of: has_primary_input CHEBI:16991 @@ -114728,7 +115127,7 @@ name: catalytic activity, acting on RNA namespace: molecular_function def: "Catalytic activity that acts to modify RNA, driven by ATP hydrolysis." [GOC:molecular_function_refactoring, GOC:pdt] subset: goslim_generic -subset: prokaryote_subset +subset: goslim_prokaryote is_a: GO:0003824 ! catalytic activity intersection_of: GO:0003824 ! catalytic activity intersection_of: has_primary_input CHEBI:33697 @@ -115258,6 +115657,16 @@ relationship: part_of GO:0005634 ! nucleus created_by: pg creation_date: 2020-09-09T05:12:38Z +[Term] +id: GO:0140546 +name: defense response to symbiont +namespace: biological_process +def: "Reactions triggered in response to the presence of a symbiont that act to protect or prevent damage to the host." [GOC:pg] +is_a: GO:0098542 ! defense response to other organism +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20261" xsd:anyURI +created_by: pg +creation_date: 2020-11-11T17:19:06Z + [Term] id: GO:0140572 name: vacuole fission @@ -115400,6 +115809,18 @@ property_value: term_tracker_item "https://github.com/geneontology/go-ontology/i created_by: pg creation_date: 2022-12-12T09:11:06Z +[Term] +id: GO:0141124 +name: intracellular signaling cassette +namespace: biological_process +def: "An intracellular signaling module that is part of larger signaling pathways that can be initiated either intracellularly or by cell surface receptors. Intracellular signaling cassettes are discrete signaling units that are often shared by multiple signaling pathways." [GOC:ha, GOC:pg] +synonym: "intracellular signaling cascade" EXACT [] +synonym: "intracellular signaling module" EXACT [] +is_a: GO:0035556 ! intracellular signal transduction +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26557" xsd:anyURI +created_by: pg +creation_date: 2023-12-04T14:13:20Z + [Term] id: GO:0150031 name: regulation of protein localization to lysosome @@ -115450,20 +115871,6 @@ relationship: part_of GO:0030424 ! axon created_by: bc creation_date: 2018-02-19T15:04:24Z -[Term] -id: GO:0150045 -name: regulation of synaptic signaling by nitric oxide -namespace: biological_process -def: "Any process that modulates the frequency, rate or extent of synaptic signaling by nitric oxide." [GOC:aruk, GOC:bc, PMID:26311509] -subset: goslim_synapse -is_a: GO:0010646 ! regulation of cell communication -is_a: GO:0023051 ! regulation of signaling -intersection_of: GO:0065007 ! biological regulation -intersection_of: regulates GO:0099163 ! synaptic signaling by nitric oxide -relationship: regulates GO:0099163 ! synaptic signaling by nitric oxide -created_by: bc -creation_date: 2018-04-23T09:42:25Z - [Term] id: GO:0150052 name: regulation of postsynapse assembly @@ -115840,6 +116247,19 @@ property_value: term_tracker_item "https://github.com/geneontology/go-ontology/i created_by: rynl creation_date: 2023-08-29T21:05:28Z +[Term] +id: GO:0160133 +name: bicarbonate channel activity +namespace: molecular_function +def: "Enables the facilitated diffusion of a bicarbonate (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism." [PMID:18400985] +is_a: GO:0015106 ! bicarbonate transmembrane transporter activity +is_a: GO:0015267 ! channel activity +intersection_of: GO:0015267 ! channel activity +intersection_of: has_primary_input CHEBI:17544 +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26601" xsd:anyURI +created_by: rynl +creation_date: 2023-12-13T00:09:44Z + [Term] id: GO:1900006 name: positive regulation of dendrite development @@ -117582,7 +118002,7 @@ def: "The chemical reactions and pathways involving carbohydrate derivative." [G subset: goslim_agr subset: goslim_generic subset: goslim_mouse -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "carbohydrate derivative metabolism" EXACT [GOC:TermGenie] is_a: GO:0008152 ! metabolic process intersection_of: GO:0008152 ! metabolic process @@ -118645,12 +119065,14 @@ id: GO:1901564 name: organonitrogen compound metabolic process namespace: biological_process def: "The chemical reactions and pathways involving organonitrogen compound." [GOC:pr, GOC:TermGenie] +subset: gocheck_do_not_annotate synonym: "organonitrogen compound metabolism" EXACT [GOC:TermGenie] is_a: GO:0006807 ! nitrogen compound metabolic process is_a: GO:0071704 ! organic substance metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:35352 relationship: has_primary_input_or_output CHEBI:35352 +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI created_by: pr creation_date: 2012-11-04T15:17:52Z @@ -118766,7 +119188,7 @@ name: alpha-amino acid metabolic process namespace: biological_process def: "The chemical reactions and pathways involving an alpha-amino acid." [GOC:TermGenie] synonym: "alpha-amino acid metabolism" EXACT [GOC:TermGenie] -is_a: GO:0006520 ! amino acid metabolic process +is_a: GO:0008152 ! metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:78608 relationship: has_primary_input_or_output CHEBI:78608 @@ -118798,7 +119220,7 @@ synonym: "alpha-amino acid anabolism" EXACT [GOC:TermGenie] synonym: "alpha-amino acid biosynthesis" EXACT [GOC:TermGenie] synonym: "alpha-amino acid formation" EXACT [GOC:TermGenie] synonym: "alpha-amino acid synthesis" EXACT [GOC:TermGenie] -is_a: GO:0008652 ! amino acid biosynthetic process +is_a: GO:0009058 ! biosynthetic process is_a: GO:1901605 ! alpha-amino acid metabolic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:78608 @@ -119400,7 +119822,9 @@ synonym: "negative regulation of gamma-aminobutyric acid breakdown" EXACT [GOC:T synonym: "negative regulation of gamma-aminobutyric acid catabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of gamma-aminobutyric acid degradation" EXACT [GOC:TermGenie] is_a: GO:0009895 ! negative regulation of catabolic process +is_a: GO:0031324 ! negative regulation of cellular metabolic process is_a: GO:0045763 ! negative regulation of cellular amino acid metabolic process +is_a: GO:0062014 ! negative regulation of small molecule metabolic process is_a: GO:1901715 ! regulation of gamma-aminobutyric acid catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0009450 ! gamma-aminobutyric acid catabolic process @@ -119463,7 +119887,9 @@ synonym: "upregulation of gamma-aminobutyric acid catabolic process" EXACT [GOC: synonym: "upregulation of gamma-aminobutyric acid catabolism" EXACT [GOC:TermGenie] synonym: "upregulation of gamma-aminobutyric acid degradation" EXACT [GOC:TermGenie] is_a: GO:0009896 ! positive regulation of catabolic process +is_a: GO:0031325 ! positive regulation of cellular metabolic process is_a: GO:0045764 ! positive regulation of amino acid metabolic process +is_a: GO:0062013 ! positive regulation of small molecule metabolic process is_a: GO:1901715 ! regulation of gamma-aminobutyric acid catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0009450 ! gamma-aminobutyric acid catabolic process @@ -121655,6 +122081,17 @@ relationship: part_of GO:0060017 ! parathyroid gland development created_by: pr creation_date: 2014-01-21T10:03:29Z +[Term] +id: GO:1902656 +name: calcium ion import into cytosol +namespace: biological_process +def: "The directed movement of calcium ion into a cytosol." [GO_REF:0000075, GOC:TermGenie, GOC:vw] +synonym: "calcium import into cytosol" BROAD [] +is_a: GO:0006816 ! calcium ion transport +relationship: has_target_end_location GO:0005829 ! cytosol +created_by: pr +creation_date: 2014-01-22T13:41:11Z + [Term] id: GO:1902679 name: negative regulation of RNA biosynthetic process @@ -125346,63 +125783,6 @@ relationship: positively_regulates GO:0006308 ! DNA catabolic process created_by: sl creation_date: 2014-11-19T22:36:51Z -[Term] -id: GO:1903649 -name: regulation of cytoplasmic transport -namespace: biological_process -def: "Any process that modulates the frequency, rate or extent of cytoplasmic transport." [GO_REF:0000058, GOC:TermGenie, PMID:25049409] -synonym: "regulation of cytoplasmic streaming" NARROW [GOC:TermGenie] -is_a: GO:0032386 ! regulation of intracellular transport -intersection_of: GO:0065007 ! biological regulation -intersection_of: regulates GO:0016482 ! cytosolic transport -relationship: regulates GO:0016482 ! cytosolic transport -created_by: jl -creation_date: 2014-11-24T13:38:17Z - -[Term] -id: GO:1903650 -name: negative regulation of cytoplasmic transport -namespace: biological_process -def: "Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic transport." [GO_REF:0000058, GOC:TermGenie, PMID:25049409] -synonym: "down regulation of cytoplasmic streaming" NARROW [GOC:TermGenie] -synonym: "down regulation of cytoplasmic transport" EXACT [GOC:TermGenie] -synonym: "down-regulation of cytoplasmic streaming" NARROW [GOC:TermGenie] -synonym: "down-regulation of cytoplasmic transport" EXACT [GOC:TermGenie] -synonym: "downregulation of cytoplasmic streaming" NARROW [GOC:TermGenie] -synonym: "downregulation of cytoplasmic transport" EXACT [GOC:TermGenie] -synonym: "inhibition of cytoplasmic streaming" NARROW [GOC:TermGenie] -synonym: "inhibition of cytoplasmic transport" NARROW [GOC:TermGenie] -synonym: "negative regulation of cytoplasmic streaming" NARROW [GOC:TermGenie] -is_a: GO:0032387 ! negative regulation of intracellular transport -is_a: GO:1903649 ! regulation of cytoplasmic transport -intersection_of: GO:0065007 ! biological regulation -intersection_of: negatively_regulates GO:0016482 ! cytosolic transport -relationship: negatively_regulates GO:0016482 ! cytosolic transport -created_by: jl -creation_date: 2014-11-24T13:38:26Z - -[Term] -id: GO:1903651 -name: positive regulation of cytoplasmic transport -namespace: biological_process -def: "Any process that activates or increases the frequency, rate or extent of cytoplasmic transport." [GO_REF:0000058, GOC:TermGenie, PMID:25049409] -synonym: "activation of cytoplasmic streaming" NARROW [GOC:TermGenie] -synonym: "activation of cytoplasmic transport" NARROW [GOC:TermGenie] -synonym: "positive regulation of cytoplasmic streaming" NARROW [GOC:TermGenie] -synonym: "up regulation of cytoplasmic streaming" NARROW [GOC:TermGenie] -synonym: "up regulation of cytoplasmic transport" EXACT [GOC:TermGenie] -synonym: "up-regulation of cytoplasmic streaming" NARROW [GOC:TermGenie] -synonym: "up-regulation of cytoplasmic transport" EXACT [GOC:TermGenie] -synonym: "upregulation of cytoplasmic streaming" NARROW [GOC:TermGenie] -synonym: "upregulation of cytoplasmic transport" EXACT [GOC:TermGenie] -is_a: GO:0032388 ! positive regulation of intracellular transport -is_a: GO:1903649 ! regulation of cytoplasmic transport -intersection_of: GO:0065007 ! biological regulation -intersection_of: positively_regulates GO:0016482 ! cytosolic transport -relationship: positively_regulates GO:0016482 ! cytosolic transport -created_by: jl -creation_date: 2014-11-24T13:38:34Z - [Term] id: GO:1903680 name: acinar cell of sebaceous gland differentiation @@ -128440,50 +128820,6 @@ relationship: positively_regulates GO:0007528 ! neuromuscular junction developme created_by: sl creation_date: 2015-06-23T19:23:54Z -[Term] -id: GO:1904406 -name: negative regulation of nitric oxide metabolic process -namespace: biological_process -def: "Any process that stops, prevents or reduces the frequency, rate or extent of nitric oxide metabolic process." [GO_REF:0000058, GOC:TermGenie, PMID:11991626] -synonym: "down regulation of nitric oxide metabolic process" EXACT [GOC:TermGenie] -synonym: "down regulation of nitric oxide metabolism" EXACT [GOC:TermGenie] -synonym: "down-regulation of nitric oxide metabolic process" EXACT [GOC:TermGenie] -synonym: "down-regulation of nitric oxide metabolism" EXACT [GOC:TermGenie] -synonym: "downregulation of nitric oxide metabolic process" EXACT [GOC:TermGenie] -synonym: "downregulation of nitric oxide metabolism" EXACT [GOC:TermGenie] -synonym: "inhibition of nitric oxide metabolic process" NARROW [GOC:TermGenie] -synonym: "inhibition of nitric oxide metabolism" NARROW [GOC:TermGenie] -synonym: "negative regulation of nitric oxide metabolism" EXACT [GOC:TermGenie] -is_a: GO:0009892 ! negative regulation of metabolic process -is_a: GO:0080164 ! regulation of nitric oxide metabolic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: negatively_regulates GO:0046209 ! nitric oxide metabolic process -relationship: negatively_regulates GO:0046209 ! nitric oxide metabolic process -created_by: sl -creation_date: 2015-06-24T20:56:41Z - -[Term] -id: GO:1904407 -name: positive regulation of nitric oxide metabolic process -namespace: biological_process -def: "Any process that activates or increases the frequency, rate or extent of nitric oxide metabolic process." [GO_REF:0000058, GOC:TermGenie, PMID:11991626] -synonym: "activation of nitric oxide metabolic process" NARROW [GOC:TermGenie] -synonym: "activation of nitric oxide metabolism" NARROW [GOC:TermGenie] -synonym: "positive regulation of nitric oxide metabolism" EXACT [GOC:TermGenie] -synonym: "up regulation of nitric oxide metabolic process" EXACT [GOC:TermGenie] -synonym: "up regulation of nitric oxide metabolism" EXACT [GOC:TermGenie] -synonym: "up-regulation of nitric oxide metabolic process" EXACT [GOC:TermGenie] -synonym: "up-regulation of nitric oxide metabolism" EXACT [GOC:TermGenie] -synonym: "upregulation of nitric oxide metabolic process" EXACT [GOC:TermGenie] -synonym: "upregulation of nitric oxide metabolism" EXACT [GOC:TermGenie] -is_a: GO:0009893 ! positive regulation of metabolic process -is_a: GO:0080164 ! regulation of nitric oxide metabolic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: positively_regulates GO:0046209 ! nitric oxide metabolic process -relationship: positively_regulates GO:0046209 ! nitric oxide metabolic process -created_by: sl -creation_date: 2015-06-24T20:56:47Z - [Term] id: GO:1904408 name: melatonin binding @@ -130546,7 +130882,7 @@ namespace: biological_process def: "Any process that modulates the frequency, rate or extent of dense core granule transport." [GO_REF:0000058, GOC:TermGenie, PMID:22699897] comment: cdk-5 in C.elegans (G5ECH7) in PMID:22699897 (inferred from mutant phenotype). synonym: "regulation of dense core vesicle transport" EXACT [GOC:TermGenie] -is_a: GO:1903649 ! regulation of cytoplasmic transport +is_a: GO:0032386 ! regulation of intracellular transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:1901950 ! dense core granule transport relationship: regulates GO:1901950 ! dense core granule transport @@ -130568,7 +130904,7 @@ synonym: "downregulation of dense core vesicle transport" EXACT [GOC:TermGenie] synonym: "inhibition of dense core granule transport" NARROW [GOC:TermGenie] synonym: "inhibition of dense core vesicle transport" NARROW [GOC:TermGenie] synonym: "negative regulation of dense core vesicle transport" EXACT [GOC:TermGenie] -is_a: GO:1903650 ! negative regulation of cytoplasmic transport +is_a: GO:0032387 ! negative regulation of intracellular transport is_a: GO:1904809 ! regulation of dense core granule transport intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:1901950 ! dense core granule transport @@ -130591,7 +130927,7 @@ synonym: "up-regulation of dense core granule transport" EXACT [GOC:TermGenie] synonym: "up-regulation of dense core vesicle transport" EXACT [GOC:TermGenie] synonym: "upregulation of dense core granule transport" EXACT [GOC:TermGenie] synonym: "upregulation of dense core vesicle transport" EXACT [GOC:TermGenie] -is_a: GO:1903651 ! positive regulation of cytoplasmic transport +is_a: GO:0032388 ! positive regulation of intracellular transport is_a: GO:1904809 ! regulation of dense core granule transport intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:1901950 ! dense core granule transport @@ -133307,71 +133643,6 @@ relationship: positively_regulates GO:1905397 ! activated CD8-positive, alpha-be created_by: pga creation_date: 2016-08-25T09:14:10Z -[Term] -id: GO:1905427 -name: intracellular signal transduction involved in positive regulation of cell growth -namespace: biological_process -def: "Any intracellular signal transduction that is involved in positive regulation of cell growth." [GO_REF:0000060, GOC:al, GOC:TermGenie, GOC:vw, PMID:15917811] -synonym: "intracellular protein kinase cascade involved in activation of cell growth" NARROW [GOC:TermGenie] -synonym: "intracellular protein kinase cascade involved in positive regulation of cell growth" NARROW [GOC:TermGenie] -synonym: "intracellular protein kinase cascade involved in stimulation of cell growth" NARROW [GOC:TermGenie] -synonym: "intracellular protein kinase cascade involved in up regulation of cell growth" NARROW [GOC:TermGenie] -synonym: "intracellular protein kinase cascade involved in up-regulation of cell growth" NARROW [GOC:TermGenie] -synonym: "intracellular protein kinase cascade involved in upregulation of cell growth" NARROW [GOC:TermGenie] -synonym: "intracellular signal transduction involved in activation of cell growth" NARROW [GOC:TermGenie] -synonym: "intracellular signal transduction involved in stimulation of cell growth" NARROW [GOC:TermGenie] -synonym: "intracellular signal transduction involved in up regulation of cell growth" EXACT [GOC:TermGenie] -synonym: "intracellular signal transduction involved in up-regulation of cell growth" EXACT [GOC:TermGenie] -synonym: "intracellular signal transduction involved in upregulation of cell growth" EXACT [GOC:TermGenie] -synonym: "intracellular signal transduction pathway involved in activation of cell growth" NARROW [GOC:TermGenie] -synonym: "intracellular signal transduction pathway involved in positive regulation of cell growth" NARROW [GOC:TermGenie] -synonym: "intracellular signal transduction pathway involved in stimulation of cell growth" NARROW [GOC:TermGenie] -synonym: "intracellular signal transduction pathway involved in up regulation of cell growth" NARROW [GOC:TermGenie] -synonym: "intracellular signal transduction pathway involved in up-regulation of cell growth" NARROW [GOC:TermGenie] -synonym: "intracellular signal transduction pathway involved in upregulation of cell growth" NARROW [GOC:TermGenie] -synonym: "intracellular signaling cascade involved in activation of cell growth" RELATED [GOC:TermGenie] -synonym: "intracellular signaling cascade involved in positive regulation of cell growth" RELATED [GOC:TermGenie] -synonym: "intracellular signaling cascade involved in stimulation of cell growth" RELATED [GOC:TermGenie] -synonym: "intracellular signaling cascade involved in up regulation of cell growth" RELATED [GOC:TermGenie] -synonym: "intracellular signaling cascade involved in up-regulation of cell growth" RELATED [GOC:TermGenie] -synonym: "intracellular signaling cascade involved in upregulation of cell growth" RELATED [GOC:TermGenie] -synonym: "intracellular signaling chain involved in activation of cell growth" NARROW [GOC:TermGenie] -synonym: "intracellular signaling chain involved in positive regulation of cell growth" EXACT [GOC:TermGenie] -synonym: "intracellular signaling chain involved in stimulation of cell growth" NARROW [GOC:TermGenie] -synonym: "intracellular signaling chain involved in up regulation of cell growth" EXACT [GOC:TermGenie] -synonym: "intracellular signaling chain involved in up-regulation of cell growth" EXACT [GOC:TermGenie] -synonym: "intracellular signaling chain involved in upregulation of cell growth" EXACT [GOC:TermGenie] -synonym: "intracellular signaling pathway involved in activation of cell growth" RELATED [GOC:TermGenie] -synonym: "intracellular signaling pathway involved in positive regulation of cell growth" RELATED [GOC:TermGenie] -synonym: "intracellular signaling pathway involved in stimulation of cell growth" RELATED [GOC:TermGenie] -synonym: "intracellular signaling pathway involved in up regulation of cell growth" RELATED [GOC:TermGenie] -synonym: "intracellular signaling pathway involved in up-regulation of cell growth" RELATED [GOC:TermGenie] -synonym: "intracellular signaling pathway involved in upregulation of cell growth" RELATED [GOC:TermGenie] -synonym: "protein kinase cascade involved in activation of cell growth" NARROW [GOC:TermGenie] -synonym: "protein kinase cascade involved in positive regulation of cell growth" NARROW [GOC:TermGenie] -synonym: "protein kinase cascade involved in stimulation of cell growth" NARROW [GOC:TermGenie] -synonym: "protein kinase cascade involved in up regulation of cell growth" NARROW [GOC:TermGenie] -synonym: "protein kinase cascade involved in up-regulation of cell growth" NARROW [GOC:TermGenie] -synonym: "protein kinase cascade involved in upregulation of cell growth" NARROW [GOC:TermGenie] -synonym: "signal transduction via intracellular signaling cascade involved in activation of cell growth" RELATED [GOC:TermGenie] -synonym: "signal transduction via intracellular signaling cascade involved in positive regulation of cell growth" RELATED [GOC:TermGenie] -synonym: "signal transduction via intracellular signaling cascade involved in stimulation of cell growth" RELATED [GOC:TermGenie] -synonym: "signal transduction via intracellular signaling cascade involved in up regulation of cell growth" RELATED [GOC:TermGenie] -synonym: "signal transduction via intracellular signaling cascade involved in up-regulation of cell growth" RELATED [GOC:TermGenie] -synonym: "signal transduction via intracellular signaling cascade involved in upregulation of cell growth" RELATED [GOC:TermGenie] -synonym: "signal transmission via intracellular cascade involved in activation of cell growth" NARROW [GOC:TermGenie] -synonym: "signal transmission via intracellular cascade involved in positive regulation of cell growth" NARROW [GOC:TermGenie] -synonym: "signal transmission via intracellular cascade involved in stimulation of cell growth" NARROW [GOC:TermGenie] -synonym: "signal transmission via intracellular cascade involved in up regulation of cell growth" NARROW [GOC:TermGenie] -synonym: "signal transmission via intracellular cascade involved in up-regulation of cell growth" NARROW [GOC:TermGenie] -synonym: "signal transmission via intracellular cascade involved in upregulation of cell growth" NARROW [GOC:TermGenie] -is_a: GO:0035556 ! intracellular signal transduction -intersection_of: GO:0035556 ! intracellular signal transduction -intersection_of: part_of GO:0030307 ! positive regulation of cell growth -relationship: part_of GO:0030307 ! positive regulation of cell growth -created_by: dph -creation_date: 2016-09-07T18:15:01Z - [Term] id: GO:1905429 name: response to glycine @@ -134532,6 +134803,7 @@ name: regulation of calcium ion import across plasma membrane namespace: biological_process def: "Any process that modulates the frequency, rate or extent of calcium ion import across plasma membrane." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:17640527] comment: An example of this is PPP3CA in human (Q08209) in 17640527 (inferred from direct assay). +is_a: GO:0090279 ! regulation of calcium ion import is_a: GO:1903169 ! regulation of calcium ion transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0098703 ! calcium ion import across plasma membrane @@ -134549,6 +134821,7 @@ synonym: "activation of calcium ion import across plasma membrane" NARROW [GOC:T synonym: "up regulation of calcium ion import across plasma membrane" EXACT [GOC:TermGenie] synonym: "up-regulation of calcium ion import across plasma membrane" EXACT [GOC:TermGenie] synonym: "upregulation of calcium ion import across plasma membrane" EXACT [GOC:TermGenie] +is_a: GO:0090280 ! positive regulation of calcium ion import is_a: GO:1904427 ! positive regulation of calcium ion transmembrane transport is_a: GO:1905664 ! regulation of calcium ion import across plasma membrane intersection_of: GO:0065007 ! biological regulation @@ -135635,6 +135908,7 @@ synonym: "down regulation of calcium ion import across plasma membrane" EXACT [G synonym: "down-regulation of calcium ion import across plasma membrane" EXACT [GOC:TermGenie] synonym: "downregulation of calcium ion import across plasma membrane" EXACT [GOC:TermGenie] synonym: "inhibition of calcium ion import across plasma membrane" NARROW [GOC:TermGenie] +is_a: GO:0090281 ! negative regulation of calcium ion import is_a: GO:1903170 ! negative regulation of calcium ion transmembrane transport is_a: GO:1905664 ! regulation of calcium ion import across plasma membrane intersection_of: GO:0065007 ! biological regulation @@ -137142,7 +137416,9 @@ def: "Any process that stops, prevents, or reduces the frequency, rate or extent synonym: "negative regulation of glutamate metabolism" EXACT [GOC:obol] synonym: "negative regulation of glutamic acid metabolic process" EXACT [GOC:obol] synonym: "negative regulation of glutamic acid metabolism" EXACT [GOC:obol] +is_a: GO:0031324 ! negative regulation of cellular metabolic process is_a: GO:0045763 ! negative regulation of cellular amino acid metabolic process +is_a: GO:0062014 ! negative regulation of small molecule metabolic process is_a: GO:2000211 ! regulation of glutamate metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006536 ! glutamate metabolic process @@ -137158,7 +137434,9 @@ def: "Any process that activates or increases the frequency, rate or extent of g synonym: "positive regulation of glutamate metabolism" EXACT [GOC:obol] synonym: "positive regulation of glutamic acid metabolic process" EXACT [GOC:obol] synonym: "positive regulation of glutamic acid metabolism" EXACT [GOC:obol] +is_a: GO:0031325 ! positive regulation of cellular metabolic process is_a: GO:0045764 ! positive regulation of amino acid metabolic process +is_a: GO:0062013 ! positive regulation of small molecule metabolic process is_a: GO:2000211 ! regulation of glutamate metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006536 ! glutamate metabolic process @@ -137470,62 +137748,6 @@ relationship: negatively_regulates GO:0071897 ! DNA biosynthetic process created_by: yaf creation_date: 2010-12-08T04:48:20Z -[Term] -id: GO:2000282 -name: regulation of cellular amino acid biosynthetic process -namespace: biological_process -def: "Any process that modulates the frequency, rate or extent of cellular amino acid biosynthetic process." [GOC:obol] -synonym: "regulation of amino acid biosynthetic process" EXACT [GOC:obol] -synonym: "regulation of cellular amino acid anabolism" EXACT [GOC:obol] -synonym: "regulation of cellular amino acid biosynthesis" EXACT [GOC:obol] -synonym: "regulation of cellular amino acid formation" EXACT [GOC:obol] -synonym: "regulation of cellular amino acid synthesis" EXACT [GOC:obol] -is_a: GO:0006521 ! regulation of cellular amino acid metabolic process -is_a: GO:0009889 ! regulation of biosynthetic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: regulates GO:0008652 ! amino acid biosynthetic process -relationship: regulates GO:0008652 ! amino acid biosynthetic process -created_by: vw -creation_date: 2010-12-10T11:54:19Z - -[Term] -id: GO:2000283 -name: negative regulation of amino acid biosynthetic process -namespace: biological_process -def: "Any process that stops, prevents or reduces the frequency, rate or extent of an amino acid biosynthetic process." [GOC:obol] -synonym: "negative regulation of amino acid anabolism" EXACT [GOC:obol] -synonym: "negative regulation of amino acid biosynthesis" EXACT [GOC:obol] -synonym: "negative regulation of amino acid formation" EXACT [GOC:obol] -synonym: "negative regulation of amino acid synthesis" EXACT [GOC:obol] -synonym: "negative regulation of cellular amino acid biosynthetic process" EXACT [GOC:obol] -is_a: GO:0009890 ! negative regulation of biosynthetic process -is_a: GO:0045763 ! negative regulation of cellular amino acid metabolic process -is_a: GO:2000282 ! regulation of cellular amino acid biosynthetic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: negatively_regulates GO:0008652 ! amino acid biosynthetic process -relationship: negatively_regulates GO:0008652 ! amino acid biosynthetic process -created_by: vw -creation_date: 2010-12-10T11:54:23Z - -[Term] -id: GO:2000284 -name: positive regulation of amino acid biosynthetic process -namespace: biological_process -def: "Any process that activates or increases the frequency, rate or extent of cellular amino acid biosynthetic process." [GOC:obol] -synonym: "positive regulation of amino acid anabolism" EXACT [GOC:obol] -synonym: "positive regulation of amino acid biosynthesis" EXACT [GOC:obol] -synonym: "positive regulation of amino acid formation" EXACT [GOC:obol] -synonym: "positive regulation of amino acid synthesis" EXACT [GOC:obol] -synonym: "positive regulation of cellular amino acid biosynthetic process" EXACT [GOC:obol] -is_a: GO:0009891 ! positive regulation of biosynthetic process -is_a: GO:0045764 ! positive regulation of amino acid metabolic process -is_a: GO:2000282 ! regulation of cellular amino acid biosynthetic process -intersection_of: GO:0065007 ! biological regulation -intersection_of: positively_regulates GO:0008652 ! amino acid biosynthetic process -relationship: positively_regulates GO:0008652 ! amino acid biosynthetic process -created_by: vw -creation_date: 2010-12-10T11:54:27Z - [Term] id: GO:2000287 name: positive regulation of myotome development @@ -144171,6 +144393,16 @@ def: "A quality inhering in a bearer by virtue of the extent to which the bearer subset: attribute_slim is_a: PATO:0000141 ! structure +[Term] +id: PATO:0040072 +name: high nuclear/cytoplasmic ratio +namespace: quality +def: "A quality inhering in a cell by virtue of the cell having a high nuclear/cytoplasmic ratio." [http://lymerick.net/blood-cells.pdf, Wikipedia:NC_ratio&oldid=931936284] +comment: A high nuclear/cytolasmic ratio is 70% or higher. +synonym: "high N:C ratio" EXACT [] +is_a: PATO:0001396 ! cellular quality +created_by: http://orcid.org/0000-0001-5208-3432 + [Term] id: PATO:0045001 name: normal object quality @@ -157610,13 +157842,13 @@ subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim -synonym: "canalis cervicis uteri" EXACT LATIN [FMA:17740, FMA:TA] +synonym: "canalis cervicis uteri" EXACT OMO:0003011 [FMA:17740, FMA:TA] synonym: "caudal segment of uterus" EXACT [] synonym: "cervical canal" RELATED [FMA:17740] synonym: "cervical canal of uterus" EXACT [FMA:17740] synonym: "cervix" BROAD [EFO:0000979] synonym: "cervix of uterus" RELATED [BTO:0001421] -synonym: "cervix uteri" EXACT LATIN [EMAPA:29927] +synonym: "cervix uteri" EXACT OMO:0003011 [EMAPA:29927] synonym: "neck of uterus" EXACT [FMA:17740] synonym: "uterine cervix" EXACT [FMA:17740] xref: BTO:0001421 @@ -157690,7 +157922,7 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "nasal sac" EXACT SENSU [ZFA:0000047] -synonym: "nasus" RELATED LATIN [Wikipedia:Nose] +synonym: "nasus" RELATED OMO:0003011 [Wikipedia:Nose] synonym: "nose" EXACT HUMAN_PREFERRED [MA:0000281] synonym: "olfactory apparatus" RELATED [UBERON:cjm] synonym: "peripheral olfactory organ" EXACT [ZFA:0000047] @@ -157740,7 +157972,7 @@ namespace: uberon subset: functional_classification subset: uberon_slim synonym: "chemosensory sensory organ" EXACT [FBbt:00005157] -xref: FBbt:00005157 +xref: FBbt:00005157 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0000020 ! sense organ intersection_of: UBERON:0000020 ! sense organ intersection_of: capable_of GO:0007606 ! sensory perception of chemical stimulus @@ -157804,7 +158036,7 @@ subset: organ_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "glandula pituitaria" EXACT LATIN [Wikipedia:Pituitary_gland] +synonym: "glandula pituitaria" EXACT OMO:0003011 [Wikipedia:Pituitary_gland] synonym: "Hp" BROAD OMO:0003000 [BIRNLEX:1353, NIFSTD:NeuroNames_abbrevSource] synonym: "hypophysis" RELATED [ZFA:0000118] synonym: "hypophysis cerebri" RELATED [MA:0000176] @@ -157897,9 +158129,9 @@ subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "pars peripherica" EXACT LATIN [FMA:9903, FMA:TA, Wikipedia:Peripheral_nervous_system] +synonym: "pars peripherica" EXACT OMO:0003011 [FMA:9903, FMA:TA, Wikipedia:Peripheral_nervous_system] synonym: "PNS" BROAD OMO:0003000 [] -synonym: "systema nervosum periphericum" EXACT LATIN [FMA:9903, FMA:TA, Wikipedia:Peripheral_nervous_system] +synonym: "systema nervosum periphericum" EXACT OMO:0003011 [FMA:9903, FMA:TA, Wikipedia:Peripheral_nervous_system] xref: AAO:0000429 xref: BAMS:PNS xref: BILA:0000081 @@ -157911,7 +158143,7 @@ xref: EHDAA2:0001445 xref: EHDAA:2893 xref: EMAPA:16665 xref: EV:0100335 -xref: FBbt:00005098 +xref: FBbt:00005098 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:9903 xref: GAID:715 xref: MA:0000218 @@ -157947,8 +158179,8 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "parasympathetic part of autonomic division of nervous system" EXACT [] -synonym: "pars parasympathica divisionis autonomici systematis nervosi" EXACT LATIN [FMA:9907, FMA:TA] -synonym: "pars parasympathica divisionis autonomici systematis nervosi" RELATED LATIN [Wikipedia:Parasympathetic_nervous_system] +synonym: "pars parasympathica divisionis autonomici systematis nervosi" EXACT OMO:0003011 [FMA:9907, FMA:TA] +synonym: "pars parasympathica divisionis autonomici systematis nervosi" RELATED OMO:0003011 [Wikipedia:Parasympathetic_nervous_system] synonym: "PNS - parasympathetic" EXACT [] xref: AAO:0010488 xref: BIRNLEX:2517 @@ -158012,8 +158244,8 @@ subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "pars sympathica divisionis autonomici systematis nervosi" EXACT LATIN [FMA:9906, FMA:TA] -synonym: "pars sympathica divisionis autonomici systematis nervosi" RELATED LATIN [Wikipedia:Sympathetic_nervous_system] +synonym: "pars sympathica divisionis autonomici systematis nervosi" EXACT OMO:0003011 [FMA:9906, FMA:TA] +synonym: "pars sympathica divisionis autonomici systematis nervosi" RELATED OMO:0003011 [Wikipedia:Sympathetic_nervous_system] synonym: "sympathetic nervous system" EXACT [] synonym: "sympathetic part of autonomic division of nervous system" EXACT [] xref: AAO:0010487 @@ -158120,6 +158352,7 @@ xref: EMAPA:35305 xref: EV:0100129 xref: FMA:16018 xref: MA:0001582 +xref: MESH:D007515 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} xref: NCIT:C32509 xref: SCTID:361339003 xref: TAO:0001260 @@ -158164,7 +158397,7 @@ xref: EMAPA:35328 xref: EV:0100093 xref: FMA:16017 xref: MA:0002415 -xref: MESH:D046790 +xref: MESH:D046790 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: NCIT:C32546 xref: SCTID:248202004 xref: TAO:0001249 @@ -158201,9 +158434,9 @@ synonym: "insect eye" RELATED [] synonym: "Komplexauge" RELATED [BTO:0001921] synonym: "zusammengesetztes Auge" RELATED [BTO:0001921] xref: BTO:0001921 -xref: FBbt:00004508 +xref: FBbt:00004508 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: HAO:0000217 -xref: IDOMAL:0002421 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: IDOMAL:0002421 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: TGMA:0000024 xref: Wikipedia:Compound_eye is_a: UBERON:0015165 ! multi-unit eye @@ -158227,7 +158460,7 @@ synonym: "eye" BROAD [FMA:54448] synonym: "eyes" RELATED OMO:0003004 [TAO:0000107] synonym: "orbital part of face" RELATED [FMA:54448] synonym: "orbital region" RELATED [FMA:54448] -synonym: "regio orbitalis" EXACT LATIN [FMA:54448, FMA:TA] +synonym: "regio orbitalis" EXACT OMO:0003011 [FMA:54448, FMA:TA] synonym: "vertebrate eye" NARROW [] xref: AAO:0010340 xref: BIRNLEX:1169 @@ -158282,7 +158515,7 @@ xref: CALOHA:TS-2043 xref: EHDAA2:0001824 xref: EHDAA:500 xref: EMAPA:35955 -xref: FBbt:00005155 +xref: FBbt:00005155 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: GAID:63 xref: HAO:0000930 xref: MA:0000017 @@ -158351,7 +158584,7 @@ xref: EFO:0000799 xref: EHDAA2:0003193 xref: EMAPA:37283 {source="MA:th"} xref: EV:0100155 -xref: FBbt:00007000 +xref: FBbt:00007000 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: HAO:0000144 xref: MAT:0000023 xref: MESH:D005121 @@ -158379,7 +158612,7 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "lymph gland" RELATED [VHOG:0001273] -synonym: "nodus lymphaticus" RELATED LATIN [Wikipedia:Lymph_node] +synonym: "nodus lymphaticus" RELATED OMO:0003011 [Wikipedia:Lymph_node] xref: BTO:0000784 xref: CALOHA:TS-0579 xref: EFO:0000872 @@ -158522,7 +158755,7 @@ namespace: uberon def: "An ovarian follicle that has one layer of granulosa cells." [GO:0001545, GOC:mtg_mpo, http://ovary.stanford.edu] subset: human_reference_atlas subset: pheno_slim -synonym: "folliculus ovaricus primarius" EXACT LATIN [FMA:18634] +synonym: "folliculus ovaricus primarius" EXACT OMO:0003011 [FMA:18634] synonym: "ovary primary follicle" EXACT [EMAPA:35631, MA:0002907] synonym: "preantral follicle of ovary" RELATED [] synonym: "primary egg follicle" RELATED [] @@ -158579,7 +158812,7 @@ subset: pheno_slim subset: uberon_slim synonym: "antral follicle" BROAD [] synonym: "antral ovarian follicle" EXACT [GO:0001547] -synonym: "folliculi ovarici vesiculosi" EXACT LATIN [FMA:18641, FMA:TA] +synonym: "folliculi ovarici vesiculosi" EXACT OMO:0003011 [FMA:18641, FMA:TA] synonym: "folliculus ovaricus tertiarius" EXACT [] synonym: "folliculus ovaricus tertiarius (vesiculosus)" EXACT [FMA:18641] synonym: "folliculus ovaricus tertiarius (vesiculous)" EXACT [] @@ -158613,8 +158846,8 @@ subset: human_reference_atlas subset: uberon_slim synonym: "antral fluid, ovarian follicle" RELATED [] synonym: "liquor follicularis" EXACT [FMA:18665] -synonym: "liquor folliculi" EXACT LATIN [] -synonym: "liquor folliculi" RELATED LATIN [Wikipedia:Follicular_fluid] +synonym: "liquor folliculi" EXACT OMO:0003011 [] +synonym: "liquor folliculi" RELATED OMO:0003011 [Wikipedia:Follicular_fluid] synonym: "ovarian follicular fluid" RELATED [BTO:0004383] synonym: "ovary follicle fluid" EXACT [MA:0002511] synonym: "ovary follicular fluid" RELATED [BTO:0004383] @@ -158648,7 +158881,7 @@ subset: human_reference_atlas subset: uberon_slim synonym: "antral cavity" EXACT [FMA:18675] synonym: "antrum folliculare" EXACT [FMA:18675] -synonym: "antrum follicularum" RELATED LATIN [Wikipedia:Follicular_antrum] +synonym: "antrum follicularum" RELATED OMO:0003011 [Wikipedia:Follicular_antrum] synonym: "ovarian follicle antrum" EXACT [GO:0001548] xref: EMAPA:37867 {source="MA:th"} xref: FMA:18675 @@ -158669,7 +158902,7 @@ def: "Multi-tissue structure that is comprised of a secretory epithelial layer ( subset: uberon_slim subset: vertebrate_core synonym: "serosa" RELATED [Wikipedia:Serous_membrane] -synonym: "tunica serosa" EXACT LATIN [FMA:9581] +synonym: "tunica serosa" EXACT OMO:0003011 [FMA:9581] synonym: "wall of serous sac" EXACT [FMA:9581] xref: FMA:9581 xref: GAID:19 @@ -158700,7 +158933,7 @@ def: "Dense regular connective tissue that connects muscle to bone[VSAO]." [GO_R subset: pheno_slim subset: uberon_slim synonym: "sinew" RELATED [Wikipedia:Tendon] -synonym: "tendo" RELATED LATIN [Wikipedia:Tendon] +synonym: "tendo" RELATED OMO:0003011 [Wikipedia:Tendon] xref: AEO:0000091 xref: BTO:0001356 xref: CALOHA:TS-1021 @@ -158746,7 +158979,7 @@ synonym: "dorsal root ganglia" RELATED OMO:0003004 [] synonym: "dorsal root ganglion" EXACT [BTO:0001264] synonym: "DRG" RELATED OMO:0003000 [] synonym: "ganglion of dorsal root" EXACT [OBOL:automatic] -synonym: "ganglion sensorium nervi spinalis" RELATED LATIN [BTO:0001264, Wikipedia:Dorsal_root_ganglion] +synonym: "ganglion sensorium nervi spinalis" RELATED OMO:0003011 [BTO:0001264, Wikipedia:Dorsal_root_ganglion] synonym: "ganglion spinale" RELATED [BTO:0001264] synonym: "ganglion spinalis" EXACT [FMA:5888] synonym: "posterior root ganglion" RELATED [EMAPA:16668] @@ -158769,6 +159002,7 @@ xref: FMA:5888 xref: MA:0000231 xref: MA:0000232 xref: MAT:0000162 +xref: MESH:D005727 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} xref: MIAA:0000162 xref: NCIT:C12462 xref: SCTID:244455004 @@ -158873,7 +159107,7 @@ synonym: "cerebral fornix" EXACT [] synonym: "forebrain fornix" EXACT [FMA:61965] synonym: "fornix" BROAD [] synonym: "fornix (column and body of fornix)" RELATED [FMA:61965] -synonym: "fornix cerebri" RELATED LATIN [NeuroNames:268] +synonym: "fornix cerebri" RELATED OMO:0003011 [NeuroNames:268] synonym: "fornix hippocampus" RELATED [] synonym: "fornix of neuraxis" EXACT [FMA:83865] synonym: "hippocampus fornix" RELATED [] @@ -158937,7 +159171,6 @@ id: UBERON:0000054 name: macula namespace: uberon def: "Thickened areas of the saccule or utricle where the termination of the vestibular nerve occurs[MESH,modified]." [MESH:A09.246.631.909.625.125] -subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "acoustic macula" RELATED [MESH:A09.246.631.909.625.125] @@ -158953,7 +159186,6 @@ xref: ZFA:0000386 is_a: UBERON:0000479 ! tissue relationship: has_part GO:0070451 ! cell hair relationship: part_of UBERON:0001846 ! internal ear -relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens property_value: IAO:0000232 "this refers to the inner ear structure, not the macula of the retina. We follow ZFA in including a grouping class for the macula of utricle and sacule" xsd:string property_value: UBPROP:0000001 "Patches of thickened, pseudostratified epithelium of the inner ear, consisting of regular arrays of sensory hair cells interspersed with supporting cells. Each patch has its own charcteristic shape and polarity pattern. (See Anatomical Atlas entry for sensory patches of the ear by T. Whitfield.)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000386", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000007 "macular" xsd:string @@ -159075,7 +159307,7 @@ synonym: "ducts" RELATED OMO:0003004 [XAO:0004000] synonym: "exocrine duct" NARROW [] synonym: "exocrine gland duct" NARROW [] xref: AAO:0011123 -xref: FBbt:00100314 +xref: FBbt:00100314 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:30320 xref: galen:Duct xref: NCIT:C12948 @@ -159167,7 +159399,7 @@ xref: BILA:0000003 xref: CARO:0000003 xref: EHDAA2:0003003 xref: EMAPA:0 -xref: FBbt:00007001 +xref: FBbt:00007001 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:305751 xref: FMA:67135 xref: GAID:781 @@ -159452,7 +159684,7 @@ subset: vertebrate_core synonym: "glomerular capillary tuft" RELATED [ZFA:0001288] synonym: "glomerular tuft" RELATED INCONSISTENT [] synonym: "glomerulus" BROAD [] -synonym: "glomerulus renis" RELATED LATIN [Wikipedia:Glomerulus] +synonym: "glomerulus renis" RELATED OMO:0003011 [Wikipedia:Glomerulus] synonym: "Malphigian glomerulus" RELATED MISSPELLING [BTO:0000530] synonym: "Malpighian glomerulus" RELATED [http://medical-dictionary.thefreedictionary.com/malpighian+glomerulus] synonym: "Malpighian tuft" RELATED [http://medical-dictionary.thefreedictionary.com/malpighian+glomerulus] @@ -159511,7 +159743,7 @@ def: "The surface (external) layer of ectoderm which begins to proliferate short subset: pheno_slim synonym: "surface (external) ectoderm" EXACT [] synonym: "surface ectoderm" EXACT [MP:0012532] -xref: BTO:0006242 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: BTO:0006242 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: EHDAA2:0001968 xref: EHDAA:1494 xref: EHDAA:350 @@ -159565,6 +159797,7 @@ name: male reproductive system namespace: uberon def: "The organs associated with producing offspring in the gender that produces spermatozoa." [MP:0001145] subset: efo_slim +subset: human_reference_atlas subset: pheno_slim synonym: "genitalia of male organism" EXACT [OBOL:automatic] synonym: "male genital organ" RELATED [BTO:0000082] @@ -159584,7 +159817,7 @@ xref: EHDAA2:0001054 xref: EHDAA:8136 xref: EMAPA:17968 xref: EV:0100101 -xref: FBbt:00004927 +xref: FBbt:00004927 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:45664 xref: GAID:386 xref: HAO:0000505 @@ -159603,6 +159836,7 @@ intersection_of: UBERON:0000990 ! reproductive system intersection_of: part_of UBERON:0003101 ! male organism disjoint_from: UBERON:0000474 ! female reproductive system relationship: part_of UBERON:0003101 ! male organism +relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Prostate.glb" xsd:anyURI property_value: UBPROP:0000003 "By far, sexual reproduction is the more common pattern among living vertebrate forms and its widespread occurrence suggests that it is the plesiomorphic, or primitive, reproductive mode among the vertebrates.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000725", ontology="VHOG", source="ISBN:978-0792383369 Lombardi J, Comparative vertebrate reproduction (1998) p.43", source="http://bgee.unil.ch/"} @@ -159697,7 +159931,7 @@ name: mesonephric tubule namespace: uberon def: "A mesonephric tubule is an epithelial tube that is part of the mesonephros[GO]. Genital ridge that is next to the mesonephros[WP]." [Wikipedia:Mesonephric_tubules] synonym: "renal tubules" RELATED OMO:0003004 [VHOG:0000500] -synonym: "tubuli mesonephrici" RELATED LATIN [Wikipedia:Mesonephric_tubules] +synonym: "tubuli mesonephrici" RELATED OMO:0003011 [Wikipedia:Mesonephric_tubules] xref: AAO:0010389 xref: EHDAA2:0001134 xref: EMAPA:16747 @@ -159720,8 +159954,8 @@ namespace: uberon def: "An epithelial swelling on the Wolffian duct that elongates to invade the adjacent metanephric mesenchyme[MP]." [MP:0010979, PMID:19828308] subset: pheno_slim synonym: "diverticulum" RELATED [BTO:0001646] -synonym: "diverticulum metanephricum" RELATED LATIN [Wikipedia:Ureteric_bud] -synonym: "gemma ureterica" RELATED LATIN [Wikipedia:Ureteric_bud] +synonym: "diverticulum metanephricum" RELATED OMO:0003011 [Wikipedia:Ureteric_bud] +synonym: "gemma ureterica" RELATED OMO:0003011 [Wikipedia:Ureteric_bud] synonym: "metanephric bud" RELATED [BTO:0001646] synonym: "metanephric diverticulum" RELATED [Wikipedia:Metanephros#Metanephros] synonym: "ureteric ampulla" RELATED [] @@ -159821,7 +160055,7 @@ subset: efo_slim subset: pheno_slim synonym: "early embryoblast" RELATED [FMA:86557] synonym: "embryoblast" RELATED [] -synonym: "embryoblastus; massa cellularis interna; pluriblastus senior" RELATED LATIN [Wikipedia:Inner_cell_mass] +synonym: "embryoblastus; massa cellularis interna; pluriblastus senior" RELATED OMO:0003011 [Wikipedia:Inner_cell_mass] synonym: "ICM" RELATED [VHOG:0000742] synonym: "pluriblast" RELATED [] xref: EFO:0000547 @@ -159850,9 +160084,9 @@ def: "The mesectodermal cell layer arising from the trophectoderm that erodes th comment: Aggregate of cells forming the outer layer of a blastocyst, which provide nutrients to the embryo and develop into a large part of the placenta. They are formed during the first stage of pregnancy and are the first cells to differentiate from the fertilized egg. [Wikipedia:Trophoblast] subset: early_development subset: pheno_slim -synonym: "massa cellularis externa" RELATED LATIN [Wikipedia:Trophoblast] +synonym: "massa cellularis externa" RELATED OMO:0003011 [Wikipedia:Trophoblast] synonym: "trophoblast layer" EXACT [MP:0005031] -synonym: "trophoblastus" RELATED LATIN [Wikipedia:Trophoblast] +synonym: "trophoblastus" RELATED OMO:0003011 [Wikipedia:Trophoblast] synonym: "trophoderm" RELATED [BTO:0001079] xref: BTO:0001079 xref: CALOHA:TS-1070 @@ -160071,13 +160305,13 @@ synonym: "fertilized egg stage" RELATED [] synonym: "one cell stage" EXACT [] synonym: "one-cell stage" RELATED [VHOG:0000745] synonym: "zygote" RELATED [VHOG:0000745] -synonym: "zygotum" RELATED LATIN [Wikipedia:Zygote] +synonym: "zygotum" RELATED OMO:0003011 [Wikipedia:Zygote] xref: BilaDO:0000005 xref: BILS:0000106 xref: EFO:0001322 xref: EHDAA:27 xref: FBdv:00005288 -xref: IDOMAL:0000302 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: IDOMAL:0000302 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: NCIT:C12601 xref: PdumDv:0000100 xref: VHOG:0000745 @@ -160336,8 +160570,8 @@ name: lung bud namespace: uberon def: "Structure derived from foregut that becomes a lung[GO]." [GO:0060431, Wikipedia:Respiratory_bud] subset: pheno_slim -synonym: "gemma pulmonalis" RELATED LATIN [Wikipedia:Lung_buds] -synonym: "gemma respiratoria" RELATED LATIN [Wikipedia:Lung_buds] +synonym: "gemma pulmonalis" RELATED OMO:0003011 [Wikipedia:Lung_buds] +synonym: "gemma respiratoria" RELATED OMO:0003011 [Wikipedia:Lung_buds] synonym: "lung bud" RELATED OMO:0003004 [] synonym: "primary lung bud" RELATED [GO:0060572] synonym: "respiratory diverticulum" RELATED [Wikipedia:Lung_buds] @@ -160378,7 +160612,7 @@ def: "Cell layer consisting of lining cells that separates the central nervous s synonym: "BBB" RELATED [] synonym: "blood-brain barrier" EXACT [] xref: http://uri.neuinfo.org/nif/nifstd/nlx_subcell_100205 -xref: MESH:D001812 +xref: MESH:D001812 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: NCIT:C13194 xref: UMLS:C0005854 {source="ncithesaurus:Blood-Brain_Barrier"} xref: Wikipedia:Blood-brain_barrier @@ -160421,7 +160655,7 @@ synonym: "funiculus" EXACT [] synonym: "nerve fiber bundle" EXACT [FBbt:00005099] synonym: "neural fiber bundle" EXACT [] xref: CARO:0001001 -xref: FBbt:00005099 +xref: FBbt:00005099 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: NLX:147821 is_a: UBERON:0005162 ! multi cell part structure relationship: has_part GO:0043005 ! neuron projection @@ -160475,7 +160709,7 @@ name: cranial nerve nucleus namespace: uberon def: "Nucleus that receives projections from or contains neurons that send projections through one of the cranial nerves." [NLX:28532] synonym: "cranial neural nucleus" EXACT [FMA:54501] -synonym: "nucleus nervi cranialis" RELATED LATIN [Wikipedia:Cranial_nerve_nucleus] +synonym: "nucleus nervi cranialis" RELATED OMO:0003011 [Wikipedia:Cranial_nerve_nucleus] synonym: "nucleus of cranial nerve" EXACT [] xref: EMAPA:37066 {source="MA:th"} xref: FMA:54501 @@ -160554,7 +160788,7 @@ synonym: "layer of theca cells" EXACT [] synonym: "ovarian theca" RELATED [EMAPA:35636] synonym: "ovary theca" EXACT [MA:0001712] synonym: "theca cell layer of ovarian follicle" EXACT [] -synonym: "theca folliculi" RELATED LATIN [Wikipedia:Theca_of_follicle] +synonym: "theca folliculi" RELATED OMO:0003011 [Wikipedia:Theca_of_follicle] synonym: "theca of follicle" EXACT [] synonym: "thecal cell layer" EXACT [ZFA:0001113] synonym: "thecal cell layers" RELATED OMO:0003004 [ZFA:0001113] @@ -160604,7 +160838,7 @@ synonym: "anal canal viewed anatomically" EXACT [] synonym: "anal pad" RELATED [] synonym: "anatomical anal canal" EXACT [] synonym: "anus" RELATED [] -synonym: "canalis analis" RELATED LATIN [BTO:0001978, Wikipedia:Anal_canal] +synonym: "canalis analis" RELATED OMO:0003011 [BTO:0001978, Wikipedia:Anal_canal] synonym: "cloaca" RELATED [] synonym: "cloacal chamber" RELATED [] synonym: "mesenteron" RELATED [] @@ -160615,7 +160849,7 @@ xref: EMAPA:18256 xref: FMA:15703 xref: galen:AnalCanal xref: MA:0000330 -xref: MESH:D001003 +xref: MESH:D001003 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: NCIT:C12375 xref: SCTID:245438008 xref: UMLS:C0227411 {source="ncithesaurus:Anal_Canal"} @@ -160745,7 +160979,7 @@ namespace: uberon def: "The ventral part of the cloaca remaining after septation of the rectum, which further develops into part of the bladder, part of the prostatic part of the male urethra and the urethra and vestibule in females." [ISBN:0-683-40008-8, MP:0010116] subset: pheno_slim synonym: "fetal UGS" EXACT [PMID:18977204] -synonym: "sinus urogenitalis" EXACT LATIN [] +synonym: "sinus urogenitalis" EXACT OMO:0003011 [] synonym: "UGS" EXACT [MP:0010116] synonym: "urogenital sinus" BROAD [MP:0010116] xref: EHDAA2:0004060 @@ -160778,13 +161012,13 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "adult mouth" NARROW [] -synonym: "cavital oralis" RELATED LATIN [Wikipedia:Mouth] +synonym: "cavital oralis" RELATED OMO:0003011 [Wikipedia:Mouth] synonym: "cavitas oris" RELATED [BTO:0001090] synonym: "cavum oris" RELATED [BTO:0001090] synonym: "mouth cavity" RELATED [BTO:0001090] synonym: "oral region" RELATED [EHDAA2:0001326] synonym: "oral vestibule" RELATED [BTO:0001090] -synonym: "regio oralis" EXACT LATIN [BTO:0004698, FMA:49184, FMA:TA] +synonym: "regio oralis" EXACT OMO:0003011 [BTO:0004698, FMA:49184, FMA:TA] synonym: "rima oris" RELATED [BTO:0001090] synonym: "stoma" RELATED [] synonym: "stomatodaeum" RELATED [VHOG:0000812] @@ -160799,7 +161033,7 @@ xref: EFO:0000825 xref: EHDAA2:0001326 xref: EHDAA:542 xref: EMAPA:16262 -xref: FBbt:00003126 +xref: FBbt:00003126 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:49184 xref: GAID:75 xref: galen:Mouth @@ -160874,6 +161108,7 @@ xref: EMAPA:18399 xref: EV:0100057 xref: FMA:20292 xref: HAO:0000669 +xref: MESH:D009055 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} xref: NCIT:C12421 xref: SCTID:181220002 xref: TAO:0001027 @@ -160912,10 +161147,11 @@ id: UBERON:0000170 name: pair of lungs namespace: uberon def: "The pair of anatomical structures comprised of a left lung and right lung." [http://orcid.org/0000-0002-6601-2165] +subset: human_reference_atlas subset: pheno_slim synonym: "lungs" EXACT [] synonym: "lungs pair" EXACT [] -synonym: "pulmones" EXACT LATIN [FMA:68877, FMA:TA] +synonym: "pulmones" EXACT OMO:0003011 [FMA:68877, FMA:TA] synonym: "set of lungs" EXACT [] xref: FMA:68877 is_a: UBERON:0034925 ! anatomical collection @@ -160928,6 +161164,7 @@ relationship: has_member UBERON:0002168 ! left lung relationship: has_member UBERON:0002168 {cardinality="1"} ! left lung relationship: located_in UBERON:0002224 ! thoracic cavity relationship: part_of UBERON:0001558 {source="FMA-abduced"} ! lower respiratory tract +relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: UBERON:0000171 @@ -160959,8 +161196,8 @@ name: amniotic fluid namespace: uberon def: "Amniotic fluid is a bodily fluid consisting of watery liquid surrounding and cushioning a growing fetus within the amnion. It allows the fetus to move freely without the walls of the uterus being too tight against its body. Buoyancy is also provided. The composition of the fluid changes over the course of gestation. Initially, amniotic fluid is similar to maternal plasma, mainly water with electrolytes. As the fetus develops, proteins, carbohydrates, lipids, phospholipids originating from the lungs, fetal cells, and urea are deposited in the fluid." [ENVO:02000021, MP:MP] subset: pheno_slim -synonym: "acqua amnii" RELATED LATIN [BTO:0000068] -synonym: "liquor amnii" RELATED LATIN [BTO:0000068] +synonym: "acqua amnii" RELATED OMO:0003011 [BTO:0000068] +synonym: "liquor amnii" RELATED OMO:0003011 [BTO:0000068] xref: BTO:0000068 xref: CALOHA:TS-0034 xref: EMAPA:36771 @@ -161115,6 +161352,7 @@ id: UBERON:0000202 name: glial blood brain barrier namespace: uberon def: "A blood brain barrier composed of glial cells." [https://orcid.org/0000-0002-6601-2165] +xref: FBbt:00007091 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0000120 ! blood brain barrier intersection_of: UBERON:0000120 ! blood brain barrier intersection_of: composed_primarily_of CL:0000125 ! glial cell @@ -161186,7 +161424,7 @@ subset: pheno_slim synonym: "frontal" NARROW [AAO:0000206] synonym: "frontal bone" NARROW SENSU [FMA:52734, MA:0001466] synonym: "os frontal" NARROW SENSU [Wikipedia:Frontal_bone] -synonym: "os frontale" RELATED LATIN [Wikipedia:Frontal_bone] +synonym: "os frontale" RELATED OMO:0003011 [Wikipedia:Frontal_bone] xref: AAO:0000206 xref: EMAPA:19016 xref: FMA:52734 @@ -161264,7 +161502,6 @@ relationship: part_of UBERON:0001093 ! vertebral bone 2 id: UBERON:0000219 name: vertebral foramen of atlas namespace: uberon -def: "." [Wikipedia:Atlas_(anatomy)#Vertebral_foramen] synonym: "vertebral foramen of cervical vertebra 1" EXACT [] xref: FMA:24293 xref: SCTID:281228008 @@ -161281,14 +161518,14 @@ name: atlanto-occipital joint namespace: uberon def: "The Atlanto-occipital joint (articulation between the atlas and the occipital bone) consists of a pair of condyloid joints. The atlanto-occipital joint is a synovial joint. The ligaments connecting the bones are: Two Articular capsules; Posterior atlantoöccipital membrane; Anterior atlantoöccipital membrane; Lateral atlantoöccipital." [Wikipedia:Atlanto-occipital_joint] synonym: "articulatio atlanto-occipitalis" EXACT [FMA:24939] -synonym: "articulatio atlantooccipitalis" RELATED LATIN [Wikipedia:Atlanto-occipital_joint] +synonym: "articulatio atlantooccipitalis" RELATED OMO:0003011 [Wikipedia:Atlanto-occipital_joint] synonym: "atlanto occipital joint" EXACT [] synonym: "atlantooccipital joint" EXACT [] synonym: "craniovertebral joint" EXACT [FMA:24939] synonym: "occipito atlantal joint" EXACT [] synonym: "occipito-atlantal joint" EXACT [] xref: FMA:24939 -xref: MESH:D001269 +xref: MESH:D001269 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: NCIT:C32158 xref: ncithesaurus:Atlanto-occipital_Joint-Atlanto xref: SCTID:361831006 @@ -161311,7 +161548,7 @@ name: tendon sheath namespace: uberon def: "A layer of membrane around a tendon. It has 2 layers: synovial sheath + fibrous tendon sheath." [Wikipedia:Tendon_sheath] synonym: "synovial tendon sheath" EXACT [FMA:45087] -synonym: "vagina tendinis" RELATED LATIN [Wikipedia:Tendon_sheath] +synonym: "vagina tendinis" RELATED OMO:0003011 [Wikipedia:Tendon_sheath] xref: BTO:0000051 xref: FMA:45087 xref: FMA:76715 @@ -161413,7 +161650,7 @@ name: breast namespace: uberon def: "The upper ventral region of the torso of an organism." [Wikipedia:Breast] subset: pheno_slim -synonym: "mamma" RELATED LATIN [Wikipedia:Breast] +synonym: "mamma" RELATED OMO:0003011 [Wikipedia:Breast] synonym: "mammary part of chest" EXACT [FMA:9601] synonym: "mammary region" EXACT [FMA:9601] xref: BTO:0000149 @@ -161492,10 +161729,10 @@ name: subarachnoid space namespace: uberon def: "The space between the arachnoid and pia mater." [GOC:add, https://sourceforge.net/p/obo/mammalian-phenotype-requests/1168/, Wikipedia:Subarachnoid_space] subset: pheno_slim -synonym: "cavitas subarachnoidea" RELATED LATIN [BTO:0000230] -synonym: "cavum subarachnoideale" RELATED LATIN [Wikipedia:Subarachnoid_space] -synonym: "spatium leptomeningeum" RELATED LATIN [BTO:0000230] -synonym: "spatium subarachnoideum" RELATED LATIN [BTO:0000230, Wikipedia:Subarachnoid_space] +synonym: "cavitas subarachnoidea" RELATED OMO:0003011 [BTO:0000230] +synonym: "cavum subarachnoideale" RELATED OMO:0003011 [Wikipedia:Subarachnoid_space] +synonym: "spatium leptomeningeum" RELATED OMO:0003011 [BTO:0000230] +synonym: "spatium subarachnoideum" RELATED OMO:0003011 [BTO:0000230, Wikipedia:Subarachnoid_space] synonym: "subarachnoid cavity" RELATED [BTO:0000230] synonym: "subarachnoid space of central nervous system" EXACT [] synonym: "subarachnoid space of CNS" EXACT [] @@ -161601,7 +161838,7 @@ synonym: "fetus" NARROW [BTO:0000449] xref: BTO:0000449 xref: CALOHA:TS-0360 xref: EFO:0001323 -xref: FBbt:00005333 +xref: FBbt:00005333 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:63919 xref: GAID:552 xref: MESH:D005333 @@ -161697,7 +161934,7 @@ name: yellow bone marrow namespace: uberon def: "Bone marrow in which the fat cells predominate in the meshes of the reticular network." [http://medical-dictionary.thefreedictionary.com/Yellow+Marrow] synonym: "fat marrow" RELATED [BTO:0000635] -synonym: "medulla ossium flava" EXACT LATIN [BTO:0000635] +synonym: "medulla ossium flava" EXACT OMO:0003011 [BTO:0000635] synonym: "yellow marrow" EXACT [BTO:0000635] xref: BTO:0000635 xref: FMA:74596 @@ -161772,7 +162009,7 @@ synonym: "mucosal region" EXACT [FMA:85358] synonym: "mucous membrane" EXACT [FMA:85355] synonym: "organ mucosa" EXACT [FMA:85355] synonym: "region of mucosa" RELATED [FMA:85358] -synonym: "tunica mucosa" RELATED LATIN [BTO:0000886, Wikipedia:Mucous_membrane] +synonym: "tunica mucosa" RELATED OMO:0003011 [BTO:0000886, Wikipedia:Mucous_membrane] xref: AEO:0000199 xref: BTO:0000886 xref: CALOHA:TS-2031 @@ -161814,8 +162051,8 @@ synonym: "first division of fifth cranial nerve" EXACT [FMA:52621] synonym: "first division of trigeminal nerve" EXACT [FMA:52621] synonym: "nervus ophthalmicus (V1)" EXACT [FMA:52621] synonym: "nervus ophthalmicus (Va)" EXACT [FMA:52621] -synonym: "nervus ophthalmicus [v1]" EXACT LATIN [FMA:52621, FMA:TA] -synonym: "nervus ophthalmicus [va]" EXACT LATIN [FMA:52621, FMA:TA] +synonym: "nervus ophthalmicus [v1]" EXACT OMO:0003011 [FMA:52621, FMA:TA] +synonym: "nervus ophthalmicus [va]" EXACT OMO:0003011 [FMA:52621, FMA:TA] synonym: "ophthalmic division" RELATED [BTO:0000926, Wikipedia:Ophthalmic_nerve] synonym: "ophthalmic division [V1]" EXACT [FMA:52621] synonym: "ophthalmic division [Va]" EXACT [FMA:52621] @@ -161885,7 +162122,7 @@ name: nuchal ligament namespace: uberon def: "A fibrous membrane, which, in the neck, represents the supraspinal ligaments of the upper vertebrae." [Wikipedia:Nuchal_ligament] synonym: "ligament of neck" EXACT [FMA:13427] -synonym: "ligamentum nuchae" EXACT LATIN [FMA:13427] +synonym: "ligamentum nuchae" EXACT OMO:0003011 [FMA:13427] synonym: "paddywhack" NARROW [NCBITaxon:9895, Wikipedia:Paddywhack] synonym: "paxwax" RELATED [] xref: BTO:0000952 @@ -161911,7 +162148,8 @@ id: UBERON:0000353 name: parenchyma namespace: uberon def: "Functional part of an organ in the body. This is in contrast to the stroma, which refers to the structural tissue of organs, being exactly, connective tissues." [Wikipedia:Parenchyma] -xref: BTO:0001539 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: BTO:0000999 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} +xref: BTO:0001539 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: EHDAA:3015 xref: EHDAA:3905 xref: EHDAA:3999 @@ -161951,7 +162189,7 @@ synonym: "pharynx mucosa" EXACT [OBOL:automatic] synonym: "pharynx mucosa of organ" EXACT [OBOL:automatic] synonym: "pharynx mucous membrane" EXACT [OBOL:automatic] synonym: "pharynx organ mucosa" EXACT [OBOL:automatic] -synonym: "tunica mucosa pharyngea" EXACT LATIN [FMA:55031, FMA:TA] +synonym: "tunica mucosa pharyngea" EXACT OMO:0003011 [FMA:55031, FMA:TA] synonym: "tunica mucosa pharyngis" EXACT [] xref: BTO:0001047 xref: EMAPA:26957 @@ -161969,7 +162207,7 @@ name: blastocyst namespace: uberon def: "The mammalian blastocyst is a hollow ball of cells containing two cell types, the inner cell mass and the trophectoderm[GO]." [GO:0001824, Wikipedia:Blastocyst] subset: efo_slim -synonym: "blastocystis" RELATED LATIN [Wikipedia:Blastocyst] +synonym: "blastocystis" RELATED OMO:0003011 [Wikipedia:Blastocyst] synonym: "blastula" RELATED [FMA:83041] xref: BTO:0001099 xref: CALOHA:TS-0076 @@ -161998,7 +162236,7 @@ id: UBERON:0000361 name: red bone marrow namespace: uberon def: "The red vascular substance consisting of connective tissue and blood vessels, containing primitive blood cells, macrophages, megakaryocytes, and fat cells. Red marrow is found in the cavities of many bones. It manufactures and releases leukocytes and erythrocytes into the bloodstream." [http://medical-dictionary.thefreedictionary.com/red+marrow] -synonym: "medulla ossium rubra" EXACT LATIN [BTO:0001160] +synonym: "medulla ossium rubra" EXACT OMO:0003011 [BTO:0001160] synonym: "parenchyma of none marrow marrow" RELATED [http://orcid.org/0000-0002-6601-2165] synonym: "parenchymal red marrow" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "red marrow" EXACT [BTO:0001160] @@ -162022,9 +162260,9 @@ subset: human_reference_atlas subset: pheno_slim synonym: "kidney medulla" EXACT [OBOL:automatic] synonym: "medulla of kidney" EXACT [OBOL:automatic] -synonym: "medulla renalis" EXACT LATIN [FMA:74268, FMA:TA] +synonym: "medulla renalis" EXACT OMO:0003011 [FMA:74268, FMA:TA] synonym: "medullary pyramids" RELATED OMO:0003004 [FMA:74268] -synonym: "pyramides renales" EXACT LATIN [FMA:74268, FMA:TA] +synonym: "pyramides renales" EXACT OMO:0003011 [FMA:74268, FMA:TA] synonym: "renal marrow" RELATED [BTO:0001167] synonym: "renal medullae" EXACT OMO:0003004 [FMA:86327] synonym: "renal medullae set" EXACT OMO:0003004 [FMA:86327] @@ -162125,7 +162363,7 @@ name: syncytiotrophoblast namespace: uberon def: "Extraembryonic cells of trophoblastic shell surrounding embryo, outside the cytotrophoblast layer, involved with implantation of the blastocyst by eroding extracellular matrix surrounding maternal endometrial cells at site of implantation, also contribute to villi. (dark staining, multinucleated)." [http://embryology.med.unsw.edu.au/Notes/placenta5.htm, Wikipedia:Syncytiotrophoblast] synonym: "syncitiotrophoblast" RELATED [] -synonym: "syncitiotrophoblastus" RELATED LATIN [Wikipedia:Syncytiotrophoblast] +synonym: "syncitiotrophoblastus" RELATED OMO:0003011 [Wikipedia:Syncytiotrophoblast] synonym: "syncytial trophoblast" EXACT [FMA:83040] synonym: "syntrophoblast" RELATED [] synonym: "syntrophoblast layer" EXACT [ISBN:0073040584] @@ -162157,11 +162395,11 @@ synonym: "mandibular division of fifth cranial nerve" EXACT [FMA:52996] synonym: "mandibular division of trigeminal nerve [Vc; V3]" EXACT [FMA:52996] synonym: "mandibular nerve [V3]" EXACT [FMA:52996] synonym: "mandibular nerve [Vc]" EXACT [FMA:52996] -synonym: "n. mandibularis" RELATED LATIN [Wikipedia:Mandibular_nerve] +synonym: "n. mandibularis" RELATED OMO:0003011 [Wikipedia:Mandibular_nerve] synonym: "nervus mandibularis" RELATED [BTO:0001375] -synonym: "nervus mandibularis [v3]" EXACT LATIN [FMA:52996, FMA:TA] +synonym: "nervus mandibularis [v3]" EXACT OMO:0003011 [FMA:52996, FMA:TA] synonym: "nervus mandibularis [Vc; V3]" EXACT [FMA:52996] -synonym: "nervus mandibularis [vc]" EXACT LATIN [FMA:52996, FMA:TA] +synonym: "nervus mandibularis [vc]" EXACT OMO:0003011 [FMA:52996, FMA:TA] synonym: "ramus mandibularis (ramus V3)" EXACT [AAO:0010688] synonym: "third division of fifth cranial nerve" EXACT [FMA:52996] synonym: "third division of trigeminal nerve" EXACT [FMA:52996] @@ -162193,7 +162431,7 @@ namespace: uberon def: "The part of the hindlimb between pelvis and the knee, corresponding to the femur." [http://orcid.org/0000-0002-6601-2165] subset: efo_slim subset: pheno_slim -synonym: "femur" RELATED LATIN [Wikipedia:Thigh] +synonym: "femur" RELATED OMO:0003011 [Wikipedia:Thigh] synonym: "hind limb stylopod" EXACT [OBOL:automatic] synonym: "hind limb stylopodium" EXACT [VHOG:0000349] synonym: "hind propodium" EXACT [AAO:0000887] @@ -162247,11 +162485,11 @@ synonym: "maxillary division of fifth cranial nerve" EXACT [FMA:52724] synonym: "maxillary division of trigeminal nerve (Vb; V2)" EXACT [FMA:52724] synonym: "maxillary nerve [V2]" EXACT [FMA:52724] synonym: "maxillary nerve [Vb]" EXACT [FMA:52724] -synonym: "n. maxillaris" RELATED LATIN [Wikipedia:Maxillary_nerve] +synonym: "n. maxillaris" RELATED OMO:0003011 [Wikipedia:Maxillary_nerve] synonym: "nervus maxillaris" RELATED [BTO:0001378] synonym: "nervus maxillaris (Vb; V2)" EXACT [FMA:52724] -synonym: "nervus maxillaris [v2]" EXACT LATIN [FMA:52724, FMA:TA] -synonym: "nervus maxillaris [vb]" EXACT LATIN [FMA:52724, FMA:TA] +synonym: "nervus maxillaris [v2]" EXACT OMO:0003011 [FMA:52724, FMA:TA] +synonym: "nervus maxillaris [vb]" EXACT OMO:0003011 [FMA:52724, FMA:TA] synonym: "ramus maxillaris (ramus V2)" EXACT [AAO:0010670] synonym: "second division of fifth cranial nerve" EXACT [FMA:52724] synonym: "second division of trigeminal nerve" EXACT [FMA:52724] @@ -162283,7 +162521,7 @@ def: "The muscular portion of the tongue." [MP:0004136, Wikipedia:Muscles_of_ton subset: pheno_slim synonym: "muscle of tongue" EXACT [FMA:46689] synonym: "muscle organ of tongue" EXACT [OBOL:accepted] -synonym: "musculi linguae" RELATED LATIN [Wikipedia:Muscles_of_tongue] +synonym: "musculi linguae" RELATED OMO:0003011 [Wikipedia:Muscles_of_tongue] synonym: "skeletal muscle tissue of tongue" EXACT [OBOL:automatic] synonym: "tongue skeletal muscle" EXACT [OBOL:automatic] synonym: "tongue skeletal muscle tissue" EXACT [OBOL:automatic] @@ -162332,7 +162570,7 @@ synonym: "trachea mucous membrane" EXACT [OBOL:automatic] synonym: "trachea organ mucosa" EXACT [OBOL:automatic] synonym: "tracheal mucous membrane" EXACT [FMA:7471] synonym: "tunica mucosa (tracheae)" EXACT [FMA:7471] -synonym: "tunica mucosa tracheae" EXACT LATIN [FMA:7471, FMA:TA] +synonym: "tunica mucosa tracheae" EXACT OMO:0003011 [FMA:7471, FMA:TA] synonym: "windpipe mucosa" EXACT [OBOL:automatic] synonym: "windpipe mucosa of organ" EXACT [OBOL:automatic] synonym: "windpipe mucous membrane" EXACT [OBOL:automatic] @@ -162352,7 +162590,7 @@ namespace: uberon def: "Apocrine sweat glands are sweat glands composed of a coiled secretory portion located at the junction of the dermis and subcutaneous fat, from which a straight portion inserts and secretes into the infundibular portion of the hair follicle. The ducts of apocrine glands open into the canals of hair follicles. The stimulus for the secretion of apocrine sweat glands is adrenaline, which is a hormone carried in the blood[WP]." [PMID:18489347, Wikipedia:Apocrine_sweat_gland] subset: organ_slim subset: pheno_slim -synonym: "glandula sudorifera apocrina" EXACT LATIN [Wikipedia:Apocrine_sweat_gland] +synonym: "glandula sudorifera apocrina" EXACT OMO:0003011 [Wikipedia:Apocrine_sweat_gland] xref: BTO:0001458 xref: EMAPA:37426 {source="MA:th"} xref: FMA:59155 @@ -162484,7 +162722,7 @@ synonym: "cochlear part of vestibulocochlear ganglion" EXACT [http://orcid.org/0 synonym: "Corti's ganglion" EXACT [FMA:53445] synonym: "ganglion cochlearis" RELATED [BTO:0001688] synonym: "ganglion of Corti" EXACT [FMA:53445] -synonym: "ganglion spirale" RELATED LATIN [Wikipedia:Spiral_ganglion] +synonym: "ganglion spirale" RELATED OMO:0003011 [Wikipedia:Spiral_ganglion] synonym: "ganglion spirale cochleae" RELATED [BTO:0001688] synonym: "spiral ganglion" EXACT [FMA:53445] synonym: "spiral ganglion of cochlea" RELATED [BTO:0001688] @@ -162610,7 +162848,7 @@ namespace: uberon def: "The nasal vestibule is the most anterior part of the nasal cavity. It's enclosed by the cartilages of nose and lined by the same epithelium of the skin. The other part of the nasal cavity, which is lined by the respiratory epithelium, is called nasal cavity proper. [WP,unvetted]." [Wikipedia:Nasal_vestibule] synonym: "vestibular part of nasal cavity" EXACT [FMA:59644] synonym: "vestibulum nasale" RELATED [BTO:0001761] -synonym: "vestibulum nasi" RELATED LATIN [BTO:0001761, Wikipedia:Nasal_vestibule] +synonym: "vestibulum nasi" RELATED OMO:0003011 [BTO:0001761, Wikipedia:Nasal_vestibule] xref: BTO:0001761 xref: CALOHA:TS-0660 xref: FMA:59644 @@ -162626,7 +162864,7 @@ name: scalp namespace: uberon def: "The outer covering of the calvaria. It is composed of several layers: SKIN; subcutaneous connective tissue; the occipitofrontal muscle which includes the tendonous galea aponeurotica; Loose connective tissue; and the pericranium (the PERIOSTEUM of the SKULL)." [MESH:A01.456.810] subset: pheno_slim -synonym: "scalpus" RELATED LATIN [Wikipedia:Scalp] +synonym: "scalpus" RELATED OMO:0003011 [Wikipedia:Scalp] xref: BTO:0001809 xref: CALOHA:TS-0896 xref: EMAPA:37949 {source="MA:th"} @@ -162657,7 +162895,7 @@ def: "One of a a paired bundle of nerve fibers plus ganglia that run from the ba synonym: "gangliated cord" EXACT [Wikipedia:Sympathetic_trunk] synonym: "sympathetic chain" EXACT [FMA:6258] synonym: "sympathetic ganglionic chain" EXACT [Wikipedia:Sympathetic_trunk] -synonym: "truncus sympathicus" RELATED LATIN [Wikipedia:Sympathetic_trunk] +synonym: "truncus sympathicus" RELATED OMO:0003011 [Wikipedia:Sympathetic_trunk] xref: AAO:0010791 xref: BAMS:S xref: BTO:0001834 @@ -162722,7 +162960,7 @@ synonym: "mucous membrane of bronchus" EXACT [FMA:62652, OBOL:automatic] synonym: "organ mucosa of bronchi" EXACT [OBOL:automatic] synonym: "organ mucosa of bronchial trunk" EXACT [OBOL:automatic] synonym: "organ mucosa of bronchus" EXACT [OBOL:automatic] -synonym: "tunica mucosa bronchi" EXACT LATIN [FMA:62652, FMA:TA] +synonym: "tunica mucosa bronchi" EXACT OMO:0003011 [FMA:62652, FMA:TA] xref: BTO:0001846 xref: FMA:62652 xref: SCTID:30802009 @@ -162746,7 +162984,7 @@ synonym: "papilla corii" RELATED [BTO:0001858] synonym: "papilla dermatis" RELATED [BTO:0001858] synonym: "papilla dermis" RELATED [BTO:0001858] synonym: "papilla of corium" RELATED [BTO:0001858] -synonym: "papillae dermis" RELATED LATIN [Wikipedia:Dermal_papillae] +synonym: "papillae dermis" RELATED OMO:0003011 [Wikipedia:Dermal_papillae] synonym: "skin papilla" RELATED [BTO:0001858] xref: BTO:0001858 xref: CALOHA:TS-0431 @@ -162772,7 +163010,7 @@ name: mucous gland namespace: uberon def: "A gland in which the principal secretory cells are mucus secreting cells." [http://orcid.org/0000-0002-6601-2165, http://www.siumed.edu/~dking2/intro/glands.htm] subset: organ_slim -synonym: "glandula mucosa" EXACT LATIN [Wikipedia:Mucous_gland] +synonym: "glandula mucosa" EXACT OMO:0003011 [Wikipedia:Mucous_gland] synonym: "muciparous gland" RELATED [BTO:0001979] synonym: "mucous secreting gland" RELATED [] synonym: "mucus gland" RELATED [] @@ -162812,7 +163050,7 @@ name: myoepithelium namespace: uberon def: "An epithelium consisting of myopethelial cells, which are contractile cells resembling smooth muscle cells that are present in glands, notably the mammary gland, and aid in secretion. This cell has long weaving dendritic processes containing myofilament[CL]." [CL:0000185, Wikipedia:Myoepithelial_cell] synonym: "myo-epithelium" EXACT [FMA:67805] -synonym: "myoepitheliocytus" RELATED LATIN [Wikipedia:Myoepithelial_cell] +synonym: "myoepitheliocytus" RELATED OMO:0003011 [Wikipedia:Myoepithelial_cell] xref: BTO:0002308 xref: FMA:67805 xref: Wikipedia:Myoepithelial_cell @@ -162831,8 +163069,8 @@ subset: human_reference_atlas subset: organ_slim subset: pheno_slim synonym: "eccrine gland" RELATED [FMA:59154] -synonym: "glandula sudorifera eccrina" EXACT LATIN [Wikipedia:Eccrine_sweat_gland] -synonym: "glandula sudorifera merocrina" EXACT LATIN [Wikipedia:Eccrine_sweat_gland] +synonym: "glandula sudorifera eccrina" EXACT OMO:0003011 [Wikipedia:Eccrine_sweat_gland] +synonym: "glandula sudorifera merocrina" EXACT OMO:0003011 [Wikipedia:Eccrine_sweat_gland] synonym: "merocrine sweat gland" RELATED [] xref: BTO:0002323 xref: FMA:59154 @@ -162894,7 +163132,7 @@ subset: human_reference_atlas synonym: "enteric nerve plexus" EXACT [FMA:77597] synonym: "intrinsic nerve plexus" EXACT [MA:0001147] synonym: "plexus entericus" EXACT [BTO:0002437] -synonym: "plexus nervosus entericus" EXACT LATIN [FMA:77597, FMA:TA] +synonym: "plexus nervosus entericus" EXACT OMO:0003011 [FMA:77597, FMA:TA] synonym: "sympathetic enteric nerve plexus" EXACT [FMA:77597] xref: BTO:0002437 xref: EMAPA:35446 @@ -162924,7 +163162,7 @@ name: arachnoid trabecula namespace: uberon def: "The arachnoid trabeculae are delicate strands of connective tissue that loosely connect the two innermost layers of the meninges -- the arachnoid mater and the pia mater. They are found within the subarachnoid space where cerebrospinal fluid is also found. Embryologically, the trabeculae are the remnants of the common precursor that forms both the arachnoid and pial layers of the meninges." [Wikipedia:Arachnoid_trabeculae] synonym: "arachnoid trabeculae" RELATED OMO:0003004 [] -synonym: "trabecula arachnoideum" RELATED LATIN [] +synonym: "trabecula arachnoideum" RELATED OMO:0003011 [] xref: BTO:0002500 xref: FMA:83979 xref: Wikipedia:Arachnoid_trabeculae @@ -163002,7 +163240,6 @@ relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens id: UBERON:0000444 name: lymphoid follicle namespace: uberon -def: "." [https://github.com/obophenotype/uberon/issues/6, https://github.com/obophenotype/uberon/issues/7] synonym: "folliculus lymphaticus" RELATED [BTO:0002684] synonym: "lymphatic follicle" RELATED [BTO:0002684] synonym: "lymphatic nodule" RELATED [BTO:0002684] @@ -163017,6 +163254,8 @@ xref: SCTID:64626006 xref: UMLS:C0229654 {source="ncithesaurus:Lymphoid_Follicle"} is_a: UBERON:0001744 {source="FMA"} ! lymphoid tissue property_value: editor_note "introducing part_of to 'cortex of lymph node' as in issue 7 introduces equivalencies; the part_of has instead been added to 'lymph node follicle'" xsd:string +property_value: seeAlso "https://github.com/obophenotype/uberon/issues/6" xsd:anyURI +property_value: seeAlso "https://github.com/obophenotype/uberon/issues/7" xsd:anyURI [Term] id: UBERON:0000446 @@ -163024,15 +163263,15 @@ name: septum of telencephalon namespace: uberon def: "Gray matter structure located on the midline of the forebrain consisting of the septum pellucidum (in some species) and the septal nuclei (Heimer, 1996)." [BIRNLEX:963] subset: pheno_slim -synonym: "area septalis" EXACT LATIN [FMA:61842, FMA:TA] -synonym: "massa praecommissuralis" RELATED LATIN [NeuroNames:255] +synonym: "area septalis" EXACT OMO:0003011 [FMA:61842, FMA:TA] +synonym: "massa praecommissuralis" RELATED OMO:0003011 [NeuroNames:255] synonym: "Se" BROAD OMO:0003000 [PMID:23375746] synonym: "septal area" EXACT [FMA:61842] synonym: "septal region" RELATED [BAMS:SEP] synonym: "septum" BROAD [BIRNLEX:963] synonym: "septum (NN)" EXACT [FMA:61842] -synonym: "septum pellucidum (BNA,PNA)" RELATED LATIN [NeuroNames:255] -synonym: "septum telencephali" RELATED LATIN [NeuroNames:255] +synonym: "septum pellucidum (BNA,PNA)" RELATED OMO:0003011 [NeuroNames:255] +synonym: "septum telencephali" RELATED OMO:0003011 [NeuroNames:255] synonym: "telencephalon septum" EXACT [FMA:61842] xref: BAMS:SA xref: BAMS:SEP @@ -163100,7 +163339,7 @@ name: cavernous artery namespace: uberon def: "Any of several small branches of the internal carotid artery that supply the trigeminal ganglion and the walls of the cavernous and petrosal sinuses." [BTO:0002996] synonym: "cavernous branch of cavernous part of internal carotid artery" EXACT [FMA:70527] -synonym: "ramus sinus cavernosi (pars cavernosa) (arteria carotis interna)" EXACT LATIN [FMA:70527, FMA:TA] +synonym: "ramus sinus cavernosi (pars cavernosa) (arteria carotis interna)" EXACT OMO:0003011 [FMA:70527, FMA:TA] xref: BTO:0002996 xref: FMA:70527 is_a: UBERON:0001637 ! artery @@ -163167,7 +163406,7 @@ xref: CALOHA:TS-2101 xref: CARO:0000004 xref: EHDAA2:0003004 xref: EMAPA:35178 -xref: FBbt:00007019 +xref: FBbt:00007019 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:9669 xref: galen:BodySubstance xref: HAO:0000004 @@ -163202,7 +163441,7 @@ xref: AEO:0000005 xref: BILA:0000005 xref: CARO:0000005 xref: EHDAA2:0003005 -xref: FBbt:00007017 +xref: FBbt:00007017 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:5897 xref: HAO:0000005 xref: NCIT:C94478 @@ -163230,7 +163469,7 @@ xref: AEO:0000006 xref: BILA:0000006 xref: CARO:0000006 xref: EHDAA2:0003006 -xref: FBbt:00007016 +xref: FBbt:00007016 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:67165 xref: HAO:0000006 xref: TAO:0001836 @@ -163256,7 +163495,7 @@ xref: AEO:0000007 xref: BILA:0000007 xref: CARO:0000007 xref: EHDAA2:0003007 -xref: FBbt:00007015 +xref: FBbt:00007015 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:67112 xref: HAO:0000007 xref: TAO:0001835 @@ -163294,11 +163533,11 @@ xref: EHDAA2:0003011 xref: EHDAA:392 xref: EMAPA:16103 xref: EV:0100000 -xref: FBbt:00004856 +xref: FBbt:00004856 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:7149 xref: galen:AnatomicalSystem xref: HAO:0000011 -xref: IDOMAL:0002460 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: IDOMAL:0002460 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: MA:0000003 xref: NCIT:C12919 xref: SCTID:278195005 @@ -163350,7 +163589,7 @@ xref: EHDAA2:0003191 xref: EHDAA:1 xref: EMAPA:25765 xref: EV:0100016 -xref: FBbt:00000001 +xref: FBbt:00000001 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:256135 xref: galen:Organism xref: HAO:0000012 @@ -163410,7 +163649,7 @@ synonym: "male gonad" EXACT [OBOL:automatic] synonym: "orchis" RELATED [BTO:0001363] synonym: "testes" RELATED OMO:0003004 [] synonym: "testicle" EXACT [FMA:7210] -synonym: "testiculus" RELATED LATIN [BTO:0001363] +synonym: "testiculus" RELATED OMO:0003011 [BTO:0001363] xref: AAO:0000606 xref: BILA:0000124 xref: BSA:0000085 @@ -163421,7 +163660,7 @@ xref: EHDAA2:0002007 xref: EHDAA:8146 xref: EMAPA:17972 xref: EV:0100102 -xref: FBbt:00004928 +xref: FBbt:00004928 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:7210 xref: GAID:396 xref: galen:Testis @@ -163459,6 +163698,7 @@ name: female reproductive system namespace: uberon def: "The organs and associated structures associated with bearing offspring in a female animal." [http://orcid.org/0000-0002-6601-2165, MP:0001119, Wikipedia:Female_genitalia] subset: efo_slim +subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "female genital system" RELATED [] @@ -163479,7 +163719,7 @@ xref: EHDAA2:0000506 xref: EHDAA:8116 xref: EMAPA:17959 xref: EV:0100110 -xref: FBbt:00004864 +xref: FBbt:00004864 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:45663 xref: GAID:364 xref: HAO:0000324 @@ -163498,6 +163738,7 @@ is_a: UBERON:0000990 ! reproductive system intersection_of: UBERON:0000990 ! reproductive system intersection_of: part_of UBERON:0003100 ! female organism relationship: part_of UBERON:0003100 ! female organism +relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/6/68/Scheme_female_reproductive_system-en.svg" xsd:anyURI property_value: UBPROP:0000003 "By far, sexual reproduction is the more common pattern among living vertebrate forms and its widespread occurrence suggests that it is the plesiomorphic, or primitive, reproductive mode among the vertebrates.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000726", ontology="VHOG", source="ISBN:978-0792383369 Lombardi J, Comparative vertebrate reproduction (1998) p.43", source="http://bgee.unil.ch/"} @@ -163524,7 +163765,7 @@ xref: CARO:0000032 xref: EFO:0000808 xref: EHDAA2:0003032 xref: EMAPA:36031 -xref: FBbt:00007009 +xref: FBbt:00007009 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:7153 xref: galen:BodyPart xref: HAO:0000032 @@ -163567,7 +163808,7 @@ xref: AEO:0000040 xref: BILA:0000040 xref: CARO:0000040 xref: EHDAA2:0003040 -xref: FBbt:00007013 +xref: FBbt:00007013 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:63863 xref: HAO:0000040 xref: TAO:0000382 @@ -163587,8 +163828,7 @@ namespace: uberon def: "Anatomical group whose component anatomical structures lie in close proximity to each other." [FBbt:00007277] subset: common_anatomy subset: upper_level -xref: FBbt:00007277 -xref: IDOMAL:0002461 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: FBbt:00007277 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: VHOG:0001737 is_a: UBERON:0034923 ! disconnected anatomical group relationship: present_in_taxon NCBITaxon:33090 ! Viridiplantae @@ -163614,7 +163854,7 @@ xref: CALOHA:TS-2119 xref: CARO:0000042 xref: EHDAA2:0003042 xref: EHDAA:46 -xref: FBbt:00005835 +xref: FBbt:00005835 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:85537 xref: HAO:0000042 xref: NCIT:C34055 @@ -163651,7 +163891,7 @@ xref: CALOHA:TS-2090 xref: CARO:0000043 xref: EHDAA2:0003043 xref: EMAPA:35868 -xref: FBbt:00007003 +xref: FBbt:00007003 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:9637 xref: galen:Tissue xref: HAO:0000043 @@ -163686,7 +163926,7 @@ xref: AEO:0000055 xref: BILA:0000055 xref: CARO:0000055 xref: EHDAA2:0003055 -xref: FBbt:00007010 +xref: FBbt:00007010 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: HAO:0000055 xref: TAO:0001488 xref: TGMA:0001847 @@ -163720,7 +163960,7 @@ xref: CALOHA:TS-0288 xref: CARO:0000066 xref: EHDAA2:0003066 xref: EMAPA:32738 -xref: FBbt:00007005 +xref: FBbt:00007005 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:9639 xref: GAID:402 xref: HAO:0000066 @@ -163792,7 +164032,7 @@ xref: AEO:0000068 xref: BILA:0000068 xref: CARO:0000068 xref: EHDAA2_RETIRED:0003068 -xref: FBbt:00007027 +xref: FBbt:00007027 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:45567 xref: HAO:0000068 xref: NCIT:C33552 @@ -164058,11 +164298,11 @@ xref: EHDAA2:0000002 xref: EHDAA2_RETIRED:0003236 xref: EHDAA:38 xref: EMAPA:16039 -xref: FBbt:00000052 +xref: FBbt:00000052 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:69068 xref: GAID:963 xref: http://neurolex.org/wiki/Category\:Embryonic_organism -xref: IDOMAL:0000646 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: IDOMAL:0000646 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: MAT:0000226 xref: MESH:D004622 xref: MIAA:0000019 @@ -164102,7 +164342,7 @@ xref: AAO:0000480 xref: BILA:0000035 xref: BTO:0000556 xref: EMAPA:36033 -xref: FBbt:00000110 +xref: FBbt:00000110 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:69069 xref: GAID:1303 xref: MESH:D005855 @@ -164137,7 +164377,7 @@ xref: EFO:0000414 xref: EHDAA2:0000428 xref: EMAPA:16069 xref: EV:0100003 -xref: FBbt:00000111 +xref: FBbt:00000111 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:69070 xref: GAID:1304 xref: MAT:0000155 @@ -164178,7 +164418,7 @@ xref: EFO:0002545 xref: EHDAA2:0000436 xref: EMAPA:16062 xref: EV:0100005 -xref: FBbt:00000125 +xref: FBbt:00000125 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:69071 xref: GAID:1305 xref: MAT:0000175 @@ -164224,7 +164464,7 @@ xref: EHDAA:160 xref: EHDAA:183 xref: EMAPA:16083 xref: EV:0100006 -xref: FBbt:00000126 +xref: FBbt:00000126 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:69072 xref: GAID:522 xref: MAT:0000174 @@ -164268,7 +164508,7 @@ synonym: "stomodeal-hypophyseal primordium" BROAD [XAO:0000269] xref: BTO:0004224 xref: EHDAA2:0001929 xref: EMAPA:16263 -xref: FBbt:00000439 +xref: FBbt:00000439 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:295846 xref: NCIT:C34306 xref: TAO:0001290 @@ -164302,7 +164542,7 @@ synonym: "proctodaeum" EXACT [] xref: AAO:0011087 xref: EHDAA2:0000121 xref: EMAPA:25038 -xref: FBbt:00000123 +xref: FBbt:00000123 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: NCIT:C34278 xref: TAO:0000066 xref: UMLS:C0231054 {source="ncithesaurus:Proctodeum"} @@ -164334,12 +164574,12 @@ synonym: "branchial muscle" EXACT [ZFA:0000172] synonym: "branchial muscles" RELATED OMO:0003004 [TAO:0000172] synonym: "muscle of pharynx" EXACT [] synonym: "muscle organ of pharynx" EXACT [OBOL:automatic] -synonym: "musculi pharyngis" RELATED LATIN [Wikipedia:Pharyngeal_muscles] +synonym: "musculi pharyngis" RELATED OMO:0003011 [Wikipedia:Pharyngeal_muscles] synonym: "musculus pharyngis" RELATED [BTO:0001048] synonym: "pharyngeal muscle" EXACT [] synonym: "pharynx muscle" EXACT [] synonym: "pharynx muscle organ" EXACT [OBOL:automatic] -synonym: "tunica muscularis pharyngis" RELATED LATIN [Wikipedia:Pharyngeal_muscles] +synonym: "tunica muscularis pharyngis" RELATED OMO:0003011 [Wikipedia:Pharyngeal_muscles] xref: BTO:0001048 xref: EFO:0003504 xref: EMAPA:18963 @@ -164371,9 +164611,9 @@ comment: Though inaginal discs are sometimes described as “epithelial sacs”, subset: uberon_slim synonym: "imaginal disk" RELATED [] xref: BTO:0004658 -xref: FBbt:00001761 +xref: FBbt:00001761 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: MAT:0000064 -xref: MESH:D060227 +xref: MESH:D060227 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: MIAA:0000064 xref: Wikipedia:Imaginal_disc is_a: UBERON:0000481 {source="FBbt text definition"} ! multi-tissue structure @@ -164394,8 +164634,8 @@ synonym: "2n" BROAD OMO:0003000 [BIRNLEX:1640, NIFSTD:NeuroNames_abbrevSource] synonym: "CN-II" RELATED [ZFA:0000435] synonym: "cranial II" EXACT [] synonym: "nerve II" RELATED [NeuroNames:289] -synonym: "nervus opticus" EXACT LATIN [] -synonym: "nervus opticus [II]" EXACT LATIN [FMA:50863, FMA:TA] +synonym: "nervus opticus" EXACT OMO:0003011 [] +synonym: "nervus opticus [II]" EXACT OMO:0003011 [FMA:50863, FMA:TA] synonym: "optic" RELATED [TAO:0000435] synonym: "optic II" EXACT [EHDAA2:0001313] synonym: "optic II nerve" EXACT [EHDAA2:0001313] @@ -164461,7 +164701,7 @@ synonym: "anterior intestine" RELATED [] synonym: "gaster" RELATED [BTO:0001307] synonym: "mesenteron" RELATED [] synonym: "stomach chamber" NARROW [] -synonym: "ventriculus" RELATED LATIN [Wikipedia:Stomach] +synonym: "ventriculus" RELATED OMO:0003011 [Wikipedia:Stomach] xref: AAO:0000579 xref: ANISEED:1235297 xref: BTO:0001307 @@ -164551,7 +164791,7 @@ subset: grouping_class subset: human_reference_atlas subset: pheno_slim subset: uberon_slim -synonym: "arteria maxima" RELATED LATIN [Wikipedia:Aorta] +synonym: "arteria maxima" RELATED OMO:0003011 [Wikipedia:Aorta] synonym: "dorsal aorta" NARROW SENSU [Wikipedia:Aorta#In_other_animals, ZFA:0000014] synonym: "trunk of aortic tree" EXACT [] synonym: "trunk of systemic arterial tree" EXACT [] @@ -164671,7 +164911,7 @@ xref: EFO:0002969 xref: EHDAA2:0002224 xref: EMAPA:35306 xref: EV:0100128 -xref: FBbt:00005068 +xref: FBbt:00005068 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:9668 xref: GAID:439 xref: MA:0000012 @@ -164757,7 +164997,7 @@ xref: EHDAA:2641 xref: EHDAA:6485 xref: EMAPA:16894 xref: EV:0100164 -xref: FBbt:00005095 +xref: FBbt:00005095 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:50801 xref: GAID:571 xref: galen:Brain @@ -164808,8 +165048,8 @@ subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "brain cortex" RELATED [BTO:0000233] -synonym: "cortex cerebralis" RELATED LATIN [NeuroNames:39] -synonym: "cortex cerebri" RELATED LATIN [Wikipedia:Cerebral_cortex] +synonym: "cortex cerebralis" RELATED OMO:0003011 [NeuroNames:39] +synonym: "cortex cerebri" RELATED OMO:0003011 [Wikipedia:Cerebral_cortex] synonym: "cortex of cerebral hemisphere" EXACT [BTO:0000233, FMA:61830] synonym: "cortical plate (areas)" RELATED [NeuroNames:39] synonym: "cortical plate (CTXpl)" RELATED [NeuroNames:39] @@ -164901,9 +165141,9 @@ def: "A decussation of the diencephalon where the fibers of the optic nerve cros subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "chiasma" RELATED LATIN [NeuroNames:459] -synonym: "chiasma nervorum opticorum" RELATED LATIN [NeuroNames:459] -synonym: "chiasma opticum" EXACT LATIN [Wikipedia:Optic_chiasm] +synonym: "chiasma" RELATED OMO:0003011 [NeuroNames:459] +synonym: "chiasma nervorum opticorum" RELATED OMO:0003011 [NeuroNames:459] +synonym: "chiasma opticum" EXACT OMO:0003011 [Wikipedia:Optic_chiasm] synonym: "decussation of optic nerve fibers" EXACT [FMA:62045] synonym: "optic chiasm" EXACT [Wikipedia:Optic_chiasm] synonym: "optic chiasm (Rufus of Ephesus)" RELATED [NeuroNames:459] @@ -164953,7 +165193,7 @@ def: "The thoracic ganglia are paravertebral ganglia. The thoracic portion of th subset: human_reference_atlas subset: uberon_slim synonym: "ganglion of thorax" EXACT [OBOL:automatic] -synonym: "ganglion thoracicum splanchnicum" EXACT LATIN [FMA:6471, FMA:TA] +synonym: "ganglion thoracicum splanchnicum" EXACT OMO:0003011 [FMA:6471, FMA:TA] synonym: "thoracic paravertebral ganglion" EXACT [MA:0001159] synonym: "thoracic splanchnic ganglion" EXACT [] synonym: "thoracic sympathetic ganglion" EXACT [] @@ -164987,7 +165227,7 @@ subset: uberon_slim synonym: "cervical nerve" EXACT [FMA:5859] synonym: "cervical nerve tree" EXACT [] synonym: "cervical spinal nerve" EXACT [] -synonym: "nervus cervicalis" EXACT LATIN [FMA:5859, FMA:TA] +synonym: "nervus cervicalis" EXACT OMO:0003011 [FMA:5859, FMA:TA] xref: BAMS:cern xref: FMA:5859 xref: NCIT:C32299 @@ -165006,7 +165246,7 @@ property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/e/e6/Gr id: UBERON:0000963 name: head sensillum namespace: uberon -xref: FBbt:00004114 +xref: FBbt:00004114 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: MAT:0000204 xref: MIAA:0000204 is_a: UBERON:0002536 ! arthropod sensillum @@ -165191,7 +165431,7 @@ xref: BTO:0000439 xref: CALOHA:TS-0309 xref: EFO:0000827 xref: EV:0100336 -xref: FBbt:00005162 +xref: FBbt:00005162 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: GAID:69 xref: MAT:0000140 xref: MESH:D005123 @@ -165217,7 +165457,7 @@ subset: uberon_slim synonym: "omatidia" RELATED OMO:0003004 [] synonym: "omatidium" EXACT [] xref: BTO:0001922 -xref: FBbt:00004510 +xref: FBbt:00004510 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: HAO:0000666 xref: MAT:0000143 xref: MIAA:0000143 @@ -165235,7 +165475,7 @@ def: "An organism subdivision that extends from the head to the pectoral girdle, subset: efo_slim subset: pheno_slim subset: uberon_slim -synonym: "collum" RELATED LATIN [Wikipedia:Neck] +synonym: "collum" RELATED OMO:0003011 [Wikipedia:Neck] synonym: "neck (volume)" RELATED [FMA:7155] xref: AEO:0000108 xref: BTO:0000420 @@ -165475,9 +165715,9 @@ subset: pheno_slim subset: uberon_slim synonym: "femoral bone" RELATED [BTO:0001284] synonym: "mesomere 1 of pevlic appendage" RELATED HOMOLOGY [ISBN:0226313409] -synonym: "os femorale" RELATED LATIN [BTO:0001284] -synonym: "os femoris" RELATED LATIN [BTO:0001284] -synonym: "os longissimum" RELATED LATIN [Wikipedia:Femur] +synonym: "os femorale" RELATED OMO:0003011 [BTO:0001284] +synonym: "os femoris" RELATED OMO:0003011 [BTO:0001284] +synonym: "os longissimum" RELATED OMO:0003011 [Wikipedia:Femur] synonym: "proximal metapterygial mesomere of pelvic appendage" RELATED HOMOLOGY [ISBN:0226313409] synonym: "proximal metapterygial mesomere of pelvic fin" RELATED HOMOLOGY [ISBN:0226313409] synonym: "thigh bone" EXACT [] @@ -165574,7 +165814,7 @@ synonym: "hindlimb equine cannon region" NARROW [http://orcid.org/0000-0002-6601 synonym: "metatarsal part of foot" EXACT [FMA:24997] synonym: "metatarsal region" EXACT [FMA:24997] synonym: "metatarsus" RELATED [MA:0000049] -synonym: "regio metatarsalis" EXACT LATIN [FMA:24997, FMA:TA] +synonym: "regio metatarsalis" EXACT OMO:0003011 [FMA:24997, FMA:TA] xref: CALOHA:TS-2221 xref: FMA:24997 xref: MA:0000049 @@ -165596,7 +165836,7 @@ def: "Vein that drains the axilla." [http://orcid.org/0000-0002-6601-2165] subset: human_reference_atlas subset: uberon_slim synonym: "subcostal vein" RELATED [] -synonym: "vena axillaris" EXACT LATIN [Wikipedia:Axillary_vein] +synonym: "vena axillaris" EXACT OMO:0003011 [Wikipedia:Axillary_vein] xref: EMAPA:18758 xref: FMA:13329 xref: GAID:527 @@ -165626,7 +165866,7 @@ subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim -synonym: "pons cerebri" RELATED LATIN [NeuroNames:547] +synonym: "pons cerebri" RELATED OMO:0003011 [NeuroNames:547] synonym: "pons of Varolius" EXACT [] synonym: "pons Varolii" EXACT [ncithesaurus:Pons_Varolii] xref: BAMS:PONS @@ -165715,6 +165955,7 @@ namespace: uberon def: "Anatomical system that has as its parts the organs concerned with reproduction." [Wikipedia:Reproductive_system] subset: efo_slim subset: functional_classification +subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core @@ -165726,7 +165967,7 @@ synonym: "Geschlechtsorgan" RELATED [BTO:0000081] synonym: "organa genitalia" RELATED [BTO:0000081] synonym: "reproductive tissue" RELATED [BTO:0000081] synonym: "reproductive tract" RELATED [] -synonym: "systemata genitalia" RELATED LATIN [Wikipedia:Reproductive_system] +synonym: "systemata genitalia" RELATED OMO:0003011 [Wikipedia:Reproductive_system] xref: AAO:0010258 xref: BILA:0000103 xref: BTO:0000081 @@ -165736,12 +165977,13 @@ xref: EHDAA2:0001603 xref: EHDAA:5923 xref: EMAPA:17381 xref: EV:0100100 -xref: FBbt:00004857 +xref: FBbt:00004857 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:7160 xref: GAID:363 xref: HAO:0000374 xref: HAO:0000895 xref: MA:0000326 +xref: MESH:D005835 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} xref: MIAA:0000305 xref: NCIT:C12841 xref: SCTID:278875001 @@ -165773,6 +166015,7 @@ disjoint_from: UBERON:8450002 ! excretory system relationship: capable_of_part_of GO:0000003 ! reproduction relationship: existence_ends_during UBERON:0000066 ! fully formed stage relationship: has_part UBERON:0000991 ! gonad +relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens property_value: dcterms-date "2022-06-10T18:22:34Z" xsd:dateTime property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/5/52/Penis.svg" xsd:anyURI property_value: editor_note "consider splitting genitalia from reproductive system" xsd:string @@ -165797,7 +166040,7 @@ xref: BILA:0000123 xref: BSA:0000079 xref: BTO:0000534 xref: EMAPA:17383 -xref: FBbt:00004858 +xref: FBbt:00004858 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:18250 xref: GAID:368 xref: HAO:0000379 @@ -165856,7 +166099,7 @@ synonym: "gonada of female reproductive system" EXACT [OBOL:automatic] synonym: "gonada of genitalia of female organism" EXACT [OBOL:automatic] synonym: "gonada of reproductive system of female organism" EXACT [OBOL:automatic] synonym: "ovaries" RELATED OMO:0003004 [] -synonym: "ovarium" RELATED LATIN [Wikipedia:Ovary] +synonym: "ovarium" RELATED OMO:0003011 [Wikipedia:Ovary] synonym: "ovum-producing ovary" EXACT SENSU [GO:0061039] synonym: "reproductive system of female organism gonad" EXACT [OBOL:automatic] synonym: "reproductive system of female organism gonada" EXACT [OBOL:automatic] @@ -165870,7 +166113,7 @@ xref: EHDAA2:0001360 xref: EHDAA:8124 xref: EMAPA:17962 xref: EV:0100111 -xref: FBbt:00004865 +xref: FBbt:00004865 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:7209 xref: GAID:367 xref: MA:0000384 @@ -166083,7 +166326,7 @@ synonym: "gonecyst" RELATED [] synonym: "seminal gland" BROAD [] synonym: "vas efferens" RELATED [] synonym: "vesicula seminalis" RELATED [BTO:0001234, Wikipedia:Seminal_vesicle] -synonym: "vesiculae seminales" RELATED LATIN [Wikipedia:Seminal_vesicle] +synonym: "vesiculae seminales" RELATED OMO:0003011 [Wikipedia:Seminal_vesicle] synonym: "vesicular gland" RELATED [Wikipedia:Seminal_vesicle] synonym: "vesicular glands" RELATED [Wikipedia:Seminal_vesicle] synonym: "vesicular seminalis" RELATED [Wikipedia:Seminal_vesicle] @@ -166125,7 +166368,7 @@ def: "The Ejaculatory ducts (ductus ejaculatorii) are paired structures in male subset: efo_slim subset: uberon_slim synonym: "ductus ejaculatorii" EXACT OMO:0003004 [BTO:0001580] -synonym: "ductus ejaculatorii" RELATED LATIN [Wikipedia:Ejaculatory_duct] +synonym: "ductus ejaculatorii" RELATED OMO:0003011 [Wikipedia:Ejaculatory_duct] synonym: "ductus ejaculatorius" EXACT [BTO:0001580] xref: BTO:0001580 xref: CALOHA:TS-0211 @@ -166261,7 +166504,7 @@ synonym: "apparatus respiratorius" EXACT [] synonym: "apparatus respiratorius" RELATED [BTO:0000203] synonym: "Atmungssystem" RELATED [BTO:0000203] synonym: "respiratory system" EXACT [] -synonym: "systema respiratorium" RELATED LATIN [Wikipedia:Respiratory_system] +synonym: "systema respiratorium" RELATED OMO:0003011 [Wikipedia:Respiratory_system] xref: AAO:0000541 xref: BTO:0000203 xref: CALOHA:TS-1319 @@ -166354,7 +166597,7 @@ xref: BTO:0000058 xref: CALOHA:TS-1293 xref: EFO:0000793 xref: EV:0100056 -xref: FBbt:00005055 +xref: FBbt:00005055 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:7152 xref: GAID:278 xref: galen:DigestiveSystem @@ -166421,7 +166664,7 @@ xref: EHDAA2:0001601 xref: EHDAA:5901 xref: EMAPA:17366 xref: EV:0100095 -xref: FBbt:00005056 +xref: FBbt:00005056 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:7159 xref: GAID:391 xref: galen:UrinaryTract @@ -166460,9 +166703,10 @@ namespace: uberon def: "Organ system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis[WP]." [Wikipedia:Circulatory_system] subset: human_reference_atlas subset: uberon_slim -synonym: "systema cardiovasculare" RELATED LATIN [Wikipedia:Circulatory_system] +synonym: "systema cardiovasculare" RELATED OMO:0003011 [Wikipedia:Circulatory_system] xref: AAO:0000959 xref: CALOHA:TS-2103 +xref: MESH:D002319 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} xref: VHOG:0001248 xref: Wikipedia:Circulatory_system is_a: UBERON:0000467 ! anatomical system @@ -166559,7 +166803,7 @@ synonym: "muscles" RELATED [] synonym: "muscles set" EXACT [] synonym: "musculature" EXACT [] synonym: "musculature system" RELATED [] -synonym: "musculi" EXACT LATIN [FMA:32558, FMA:TA] +synonym: "musculi" EXACT OMO:0003011 [FMA:32558, FMA:TA] synonym: "set of muscles" EXACT [FMA:32558] synonym: "set of skeletal muscles" EXACT [MA:0000165] xref: AAO:0011066 @@ -166590,12 +166834,13 @@ namespace: uberon def: "The nervous system is an organ system containing predominantly neuron and glial cells. In bilaterally symmetrical organism, it is arranged in a network of tree-like structures connected to a central body. The main functions of the nervous system are to regulate and control body functions, and to receive sensory input, process this information, and generate behavior [CUMBO]." [BIRNLEX:844, ISBN:0-14-051288-8, ISBN:3110148986, NLM:nervous+system, WB:rynl, Wikipedia:Nervous_system, ZFIN:curator] subset: cumbo subset: efo_slim +subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "nerve net" NARROW [Wikipedia:Nerve_net] synonym: "neurological system" EXACT [GO:0050877] -synonym: "systema nervosum" RELATED LATIN [Wikipedia:Nervous_system] +synonym: "systema nervosum" RELATED OMO:0003011 [Wikipedia:Nervous_system] xref: AAO:0000324 xref: BILA:0000079 xref: BIRNLEX:844 @@ -166606,7 +166851,7 @@ xref: EHDAA2:0001246 xref: EHDAA:826 xref: EMAPA:16469 xref: EV:0100162 -xref: FBbt:00005093 +xref: FBbt:00005093 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:7157 xref: GAID:466 xref: MA:0000016 @@ -166642,6 +166887,7 @@ relationship: has_part CL:0000540 ! neuron relationship: immediate_transformation_of UBERON:0016880 {source="Bgee:AN"} ! future nervous system relationship: never_in_taxon NCBITaxon:6040 relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa +relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/b/b2/TE-Nervous_system_diagram.svg" xsd:anyURI property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/b/ba/Nervous_system_diagram.png" xsd:anyURI property_value: UBPROP:0000001 "A regulatory system of the body that consists of neurons and neuroglial cells. The nervous system is divided into two parts, the central nervous system (CNS) and the peripheral nervous system (PNS). (Source: BioGlossary, www.Biology-Text.com)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000396", ontology="TAO", source="ZFIN:curator"} @@ -166657,13 +166903,14 @@ namespace: uberon def: "The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the neural tube derivatives: the brain and spinal cord. In invertebrates it includes central ganglia plus nerve cord." [GO:0021551, http://www.frontiersinzoology.com/content/7/1/29, https://sourceforge.net/p/geneontology/ontology-requests/11422/] subset: cumbo subset: efo_slim +subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "cerebrospinal axis" NARROW [FMA:55675] synonym: "CNS" EXACT OMO:0003000 [] synonym: "neuraxis" RELATED [FMA:55675] -synonym: "systema nervosum centrale" EXACT LATIN [FMA:55675, FMA:TA] +synonym: "systema nervosum centrale" EXACT OMO:0003011 [FMA:55675, FMA:TA] xref: AAO:0000090 xref: BAMS:CNS xref: BILA:0000080 @@ -166676,7 +166923,7 @@ xref: EHDAA:828 xref: EMAPA:16470 xref: EMAPA:16754 xref: EV:0100163 -xref: FBbt:00005094 +xref: FBbt:00005094 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:55675 xref: GAID:570 xref: MA:0000167 @@ -166698,6 +166945,7 @@ relationship: immediate_transformation_of UBERON:0016879 {source="Bgee:AN"} ! fu relationship: never_in_taxon NCBITaxon:147099 {source="Wikipedia:Acoelomorpha"} relationship: only_in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of UBERON:0001016 ! nervous system +relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens property_value: UBPROP:0000001 "Part of the nervous system which includes the brain and spinal cord.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000090", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000001 "The brain and spinal cord. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000012", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "The central nervous system (CNS) is the part of the nervous system which includes the brain, spinal cord, and nerve cell layer of the retina (CUMBO)." xsd:string {source="BIRNLEX:1099"} @@ -166719,7 +166967,7 @@ synonym: "tract" RELATED [] synonym: "tract of neuraxis" EXACT [FMA:83847] xref: BIRNLEX:1649 xref: EV:0100304 -xref: FBbt:00005100 +xref: FBbt:00005100 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:83847 xref: NLX:147822 is_a: UBERON:0000122 ! neuron projection bundle @@ -166734,7 +166982,7 @@ def: "A slender neuron projection bundle[FBbt]; A bundle of anatomical fibers, a comment: EDITOR_NOTE note FBbt class not disjoint from tract. Consider merging with 'neuron projection bundle' subset: uberon_slim synonym: "fascicle" BROAD [FBbt:00005101] -synonym: "fasciculus" EXACT LATIN [] +synonym: "fasciculus" EXACT OMO:0003011 [] synonym: "nerve bundle" EXACT [FMA:12235] synonym: "nerve fasciculus" EXACT [FMA:12235] synonym: "nerve fiber tract" RELATED [BTO:0002191] @@ -166776,7 +167024,7 @@ xref: EHDAA:4657 xref: EMAPA:32808 xref: EMAPA:32815 xref: EV:0100371 -xref: FBbt:00005105 +xref: FBbt:00005105 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:65132 xref: FMA:65239 xref: GAID:747 @@ -166814,10 +167062,10 @@ def: "A nerve that transmits from sensory receptors on the surface of the body t subset: pheno_slim subset: uberon_slim synonym: "afferent nerve" RELATED [] -synonym: "nervus sensorius" EXACT LATIN [Wikipedia:Sensory_nerve] +synonym: "nervus sensorius" EXACT OMO:0003011 [Wikipedia:Sensory_nerve] xref: AEO:0000201 xref: EHDAA2:0003200 -xref: FBbt:00005136 +xref: FBbt:00005136 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:5868 xref: Wikipedia:Sensory_nerve is_a: UBERON:0001021 ! nerve @@ -166831,8 +167079,8 @@ def: "Anatomical system that overlaps the nervous system and is responsible for subset: efo_slim subset: uberon_slim subset: vertebrate_core -synonym: "organa sensuum" EXACT LATIN [FMA:75259, FMA:TA] -synonym: "organa sensuum" RELATED LATIN [Wikipedia:Sensory_system] +synonym: "organa sensuum" EXACT OMO:0003011 [FMA:75259, FMA:TA] +synonym: "organa sensuum" RELATED OMO:0003011 [Wikipedia:Sensory_system] synonym: "sense organ subsystem" EXACT [] synonym: "sense organs" EXACT [FMA:75259] synonym: "sense organs set" EXACT [FMA:75259] @@ -166846,7 +167094,7 @@ xref: BILA:0000099 xref: EFO:0000805 xref: EHDAA2:0003094 xref: EMAPA:16192 -xref: FBbt:00007692 +xref: FBbt:00007692 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:75259 xref: MA:0002442 xref: MAT:0000031 @@ -166966,7 +167214,7 @@ subset: uberon_slim synonym: "ch" RELATED [] synonym: "scolopophorous organ" RELATED [] xref: EFO:0000940 -xref: FBbt:00005215 +xref: FBbt:00005215 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: MAT:0000209 xref: MIAA:0000209 xref: Wikipedia:Chordotonal_organ @@ -166981,8 +167229,8 @@ def: "A sac-like expansion of the ventral wall of the intestine, narrowed into a subset: efo_slim subset: pheno_slim subset: uberon_slim -synonym: "saccus vitellinus" RELATED LATIN [Wikipedia:Yolk_sac] -synonym: "vesicula umbilicalis" RELATED LATIN [Wikipedia:Yolk_sac] +synonym: "saccus vitellinus" RELATED OMO:0003011 [Wikipedia:Yolk_sac] +synonym: "vesicula umbilicalis" RELATED OMO:0003011 [Wikipedia:Yolk_sac] xref: BTO:0001471 xref: CALOHA:TS-1130 xref: EFO:0003078 @@ -167017,15 +167265,15 @@ def: "Anterior subdivision of a digestive tract." [http://orcid.org/0000-0002-66 subset: developmental_classification subset: pheno_slim subset: uberon_slim -synonym: "praeenteron" RELATED LATIN [Wikipedia:Foregut] -synonym: "proenteron" RELATED LATIN [Wikipedia:Foregut] +synonym: "praeenteron" RELATED OMO:0003011 [Wikipedia:Foregut] +synonym: "proenteron" RELATED OMO:0003011 [Wikipedia:Foregut] xref: AAO:0011042 xref: BILA:0000085 xref: BTO:0000507 xref: EHDAA2:0000557 xref: EHDAA:520 xref: EMAPA:16548 -xref: FBbt:00005379 +xref: FBbt:00005379 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:45616 xref: MA:0001526 xref: NCIT:C34180 @@ -167152,7 +167400,7 @@ subset: functional_classification subset: organ_slim subset: pheno_slim subset: uberon_slim -synonym: "glandulae salivariae" RELATED LATIN [Wikipedia:Salivary_gland] +synonym: "glandulae salivariae" RELATED OMO:0003011 [Wikipedia:Salivary_gland] synonym: "salivary gland" EXACT [MA:0000346] xref: BTO:0001203 xref: CALOHA:TS-0892 @@ -167161,7 +167409,7 @@ xref: EHDAA2:0001775 xref: EHDAA:7987 xref: EMAPA:17751 xref: EV:0100059 -xref: FBbt:00005382 +xref: FBbt:00005382 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:9597 xref: GAID:937 xref: galen:SalivaryGland @@ -167197,14 +167445,14 @@ subset: developmental_classification subset: efo_slim subset: pheno_slim subset: uberon_slim -synonym: "mesenteron" RELATED LATIN [Wikipedia:Midgut] +synonym: "mesenteron" RELATED OMO:0003011 [Wikipedia:Midgut] xref: BILA:0000086 xref: BTO:0000863 xref: EFO:0001950 xref: EHDAA2:0001185 xref: EHDAA:983 xref: EMAPA:16255 -xref: FBbt:00005383 +xref: FBbt:00005383 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:45617 xref: MA:0001564 xref: NCIT:C34210 @@ -167230,14 +167478,14 @@ def: "The caudalmost subdivision of a digestive tract." [http://orcid.org/0000-0 subset: developmental_classification subset: pheno_slim subset: uberon_slim -synonym: "metenteron" RELATED LATIN [Wikipedia:Hindgut] +synonym: "metenteron" RELATED OMO:0003011 [Wikipedia:Hindgut] xref: AAO:0011052 xref: BILA:0000087 xref: BTO:0000510 xref: EHDAA2:0000779 xref: EHDAA:975 xref: EMAPA:16715 -xref: FBbt:00005384 +xref: FBbt:00005384 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:45618 xref: MA:0001527 xref: NCIT:C34188 @@ -167273,7 +167521,7 @@ xref: AEO:0000171 xref: BTO:0001886 xref: EFO:0001652 xref: EHDAA2:0003171 -xref: FBbt:00005495 +xref: FBbt:00005495 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:86589 xref: MAT:0000482 xref: NCIT:C34275 @@ -167293,7 +167541,7 @@ subset: uberon_slim subset: vertebrate_core synonym: "neural primordium" RELATED [] synonym: "presumptive central nervous system" RELATED [] -synonym: "tubus neuralis" RELATED LATIN [Wikipedia:Neural_tube] +synonym: "tubus neuralis" RELATED OMO:0003011 [Wikipedia:Neural_tube] xref: AAO:0010617 xref: BTO:0001057 xref: CALOHA:TS-2371 @@ -167305,7 +167553,7 @@ xref: EMAPA:16164 xref: EMAPA:16757 xref: FMA:293882 xref: MAT:0000069 -xref: MESH:D054259 +xref: MESH:D054259 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: MIAA:0000069 xref: NCIT:C34226 xref: neuronames:1365 @@ -167389,7 +167637,7 @@ synonym: "Malpighian tube" RELATED [UBERON:cjm] synonym: "tuba Malpighii" RELATED [BTO:0000810] xref: BTO:0000810 xref: EFO:0000243 -xref: FBbt:00005786 +xref: FBbt:00005786 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: GAID:1228 xref: MAT:0000123 xref: MESH:D008317 @@ -167413,7 +167661,7 @@ synonym: "corpora pedunculata" RELATED [FBbt:00005801, PMID:21062451] synonym: "mushroom bodies" EXACT OMO:0003004 [] xref: BTO:0002675 xref: EFO:0000925 -xref: FBbt:00005801 +xref: FBbt:00005801 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: GAID:1231 xref: MAT:0000336 xref: MESH:D024521 @@ -167443,7 +167691,7 @@ xref: BILA:0000000 xref: BIRNLEX:6 xref: CARO:0000000 xref: EHDAA2:0002229 -xref: FBbt:10000000 +xref: FBbt:10000000 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:62955 xref: HAO:0000000 xref: MA:0000001 @@ -167510,7 +167758,7 @@ comment: whose gel-like core is nucleus puloposus, by this definition only in ma subset: efo_slim subset: pheno_slim subset: uberon_slim -synonym: "discus intervertebralis" EXACT LATIN [FMA:10446, FMA:TA] +synonym: "discus intervertebralis" EXACT OMO:0003011 [FMA:10446, FMA:TA] synonym: "intervertebral disc" EXACT [] synonym: "intervertebral fibrocartilage" RELATED [BTO:0003625] synonym: "spinal disc" EXACT [Wikipedia:Spinal_disc] @@ -167565,7 +167813,7 @@ subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "arteria carotis externa" RELATED LATIN [Wikipedia:External_carotid_artery] +synonym: "arteria carotis externa" RELATED OMO:0003011 [Wikipedia:External_carotid_artery] synonym: "external carotid" EXACT [AAO:0010218] xref: AAO:0010218 xref: AAO:0010416 @@ -167628,7 +167876,7 @@ synonym: "inferior caval vein" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "inferior vena cava" EXACT [Wikipedia:Venae_cavae] synonym: "postcava" RELATED [] synonym: "posterior vena cava" EXACT [Wikipedia:Venae_cavae] -synonym: "vena cava inferior" RELATED LATIN [BTO:0002682, Wikipedia:Inferior_vena_cava] +synonym: "vena cava inferior" RELATED OMO:0003011 [BTO:0002682, Wikipedia:Inferior_vena_cava] xref: AAO:0011083 xref: BTO:0002682 xref: EHDAA2:0000611 @@ -167683,7 +167931,7 @@ def: "A potential space between the visceral and parietal layers of the pericard subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "cavitas pericardiaca" RELATED LATIN [Wikipedia:Pericardial_cavity] +synonym: "cavitas pericardiaca" RELATED OMO:0003011 [Wikipedia:Pericardial_cavity] synonym: "cavity of pericardial sac" EXACT [] synonym: "pericardial space" EXACT [Wikipedia:Pericardial_cavity] xref: BSA:0000091 @@ -167725,7 +167973,7 @@ synonym: "arcocentrum" NARROW INCONSISTENT [PMID:11746457] synonym: "autocentrum" NARROW [PMID:11746457, ZFA:0000126] synonym: "body of vertebra" EXACT [FMA:11945] synonym: "centra" RELATED OMO:0003004 [PHENOSCAPE:ad] -synonym: "corpus vertebra" EXACT LATIN [] +synonym: "corpus vertebra" EXACT OMO:0003011 [] synonym: "corpus vertebrae" RELATED OMO:0003004 [Wikipedia:Body_of_vertebra] synonym: "corpus vertebrae (vertebrale)" EXACT [FMA:11945] synonym: "holocentrum" NARROW [PMID:11746457] @@ -167917,7 +168165,6 @@ name: skin of trunk namespace: uberon def: "A zone of skin that is part of a trunk [Automatically generated definition]." [OBOL:automatic] comment: EDITOR_NOTE TODO - distinguish between entire skin of region and arbitrary zone of skin on region -subset: human_reference_atlas synonym: "torso zone of skin" EXACT [OBOL:automatic] synonym: "trunk skin" EXACT [] synonym: "trunk zone of skin" EXACT [OBOL:automatic] @@ -167934,7 +168181,6 @@ is_a: UBERON:0000014 ! zone of skin intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0002100 ! trunk relationship: part_of UBERON:0002100 ! trunk -relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: UBERON:0001087 @@ -168102,7 +168348,7 @@ subset: uberon_slim subset: vertebrate_core synonym: "atlas" EXACT [] synonym: "atlas (CI)" EXACT [] -synonym: "atlas [C I]" EXACT LATIN [FMA:12519, FMA:TA] +synonym: "atlas [C I]" EXACT OMO:0003011 [FMA:12519, FMA:TA] synonym: "atlas vertebra" EXACT [] synonym: "C1" BROAD [] synonym: "C1 vertebra" EXACT [] @@ -168143,7 +168389,7 @@ subset: uberon_slim subset: vertebrate_core synonym: "axis" RELATED INCONSISTENT [MA:0001422] synonym: "axis (CII)" EXACT [] -synonym: "axis [C II]" EXACT LATIN [FMA:12520, FMA:TA] +synonym: "axis [C II]" EXACT OMO:0003011 [FMA:12520, FMA:TA] synonym: "axis vertebra" EXACT [] synonym: "C2" RELATED [] synonym: "C2 vertebra" NARROW [] @@ -168246,7 +168492,7 @@ subset: human_reference_atlas subset: organ_slim subset: pheno_slim subset: uberon_slim -synonym: "musculus pectoralis minor" RELATED LATIN [Wikipedia:Pectoralis_minor_muscle] +synonym: "musculus pectoralis minor" RELATED OMO:0003011 [Wikipedia:Pectoralis_minor_muscle] synonym: "pectoralis minor muscle" EXACT [] synonym: "supracoracoideus" NARROW SENSU [] synonym: "supracoracoideus muscle" NARROW SENSU [] @@ -168370,7 +168616,7 @@ synonym: "dorsal latissimus muscle" EXACT [] synonym: "latissimi dorsi" EXACT OMO:0003004 [] synonym: "latissimus dorsi" EXACT [] synonym: "musculus latissimus dorsi" EXACT [] -synonym: "musculus latissimus dorsi" RELATED LATIN [Wikipedia:Latissimus_dorsi_muscle] +synonym: "musculus latissimus dorsi" RELATED OMO:0003011 [Wikipedia:Latissimus_dorsi_muscle] xref: EFO:0003067 xref: EHDAA2:0000932 xref: EHDAA:8307 @@ -168424,8 +168670,8 @@ subset: vertebrate_core synonym: "2nd lobe" RELATED [TAO:0005173] synonym: "gall bladder lobe" RELATED SENSU [ZFA:0005173] synonym: "liver right lobe" EXACT [] -synonym: "lobus hepaticus dexter" EXACT LATIN [] -synonym: "lobus hepatis dexter" RELATED LATIN [Wikipedia:Right_lobe_of_liver] +synonym: "lobus hepaticus dexter" EXACT OMO:0003011 [] +synonym: "lobus hepatis dexter" RELATED OMO:0003011 [Wikipedia:Right_lobe_of_liver] synonym: "right hepatic lobe" RELATED [EMAPA:18311] synonym: "right liver lobe" EXACT [ZFA:0005173] synonym: "second lobe" RELATED [TAO:0005173] @@ -168457,8 +168703,8 @@ subset: vertebrate_core synonym: "left hepatic lobe" RELATED [EMAPA:18307] synonym: "left liver lobe" EXACT [] synonym: "liver left lobe" EXACT [] -synonym: "lobus hepaticus sinister" EXACT LATIN [] -synonym: "lobus hepatis sinister" RELATED LATIN [Wikipedia:Left_lobe_of_liver] +synonym: "lobus hepaticus sinister" EXACT OMO:0003011 [] +synonym: "lobus hepatis sinister" RELATED OMO:0003011 [Wikipedia:Left_lobe_of_liver] xref: EHDAA2:0001000 xref: EHDAA:3995 xref: EMAPA:18307 @@ -168483,9 +168729,9 @@ name: lobe of thyroid gland namespace: uberon def: "A lobe of tissue that is part of a thyroid gland." [http://orcid.org/0000-0002-6601-2165] comment: The lobes of the thyroid gland are conical in shape, the apex of each being directed upward and lateralward as far as the junction of the middle with the lower third of the thyroid cartilage; the base looks downward, and is on a level with the fifth or sixth tracheal ring. Each lobe is about 5 cm. long; its greatest width is about 3 cm. , and its thickness about 2 cm. The lateral or superficial surface is convex, and covered by the skin, the superficial and deep fasciæ, the Sternocleidomastoideus, the superior belly of the Omohyoideus, the Sternohyoideus and Sternothyreoideus, and beneath the last muscle by the pretracheal layer of the deep fascia, which forms a capsule for the gland. The deep or medial surface is moulded over the underlying structures, viz. , the thyroid and cricoid cartilages, the trachea, the Constrictor pharyngis inferior and posterior part of the Cricothyreoideus, the esophagus (particularly on the left side of the neck), the superior and inferior thyroid arteries, and the recurrent nerves. The anterior border is thin, and inclines obliquely from above downward toward the middle line of the neck, while the posterior border is thick and overlaps the common carotid artery, and, as a rule, the parathyroids -synonym: "lobuli glandulae thyroideae" RELATED LATIN [Wikipedia:Lobes_of_thyroid_gland] +synonym: "lobuli glandulae thyroideae" RELATED OMO:0003011 [Wikipedia:Lobes_of_thyroid_gland] synonym: "lobus (glandula thyroidea)" EXACT [] -synonym: "lobus glandulae thyroideae" EXACT LATIN [FMA:13367, FMA:TA] +synonym: "lobus glandulae thyroideae" EXACT OMO:0003011 [FMA:13367, FMA:TA] synonym: "thyroid gland lobe" EXACT [] synonym: "thyroid lobe" EXACT [] xref: EHDAA2:0002032 @@ -168561,10 +168807,10 @@ subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "Boxer's muscle" EXACT [] -synonym: "musculus serratus anterior" RELATED LATIN [Wikipedia:Serratus_anterior_muscle] +synonym: "musculus serratus anterior" RELATED OMO:0003011 [Wikipedia:Serratus_anterior_muscle] synonym: "serratus anterior" EXACT [VHOG:0000679] synonym: "serratus anterior muscle" EXACT [] -synonym: "serratus lateralis" RELATED LATIN [Wikipedia:Serratus_anterior_muscle] +synonym: "serratus lateralis" RELATED OMO:0003011 [Wikipedia:Serratus_anterior_muscle] synonym: "serratus ventralis muscle" EXACT [] xref: EHDAA2:0001832 xref: EHDAA:9463 @@ -168646,7 +168892,7 @@ name: vertebral foramen namespace: uberon def: "A foramen within a vertebral element through which the spinal cord runs. It is formed by the anterior segment, and the posterior part, the vertebral arch." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Vertebral_foramen] subset: uberon_slim -synonym: "foramen vertebrale" RELATED LATIN [Wikipedia:Vertebral_foramen] +synonym: "foramen vertebrale" RELATED OMO:0003011 [Wikipedia:Vertebral_foramen] synonym: "vertebra neural canal" EXACT [] xref: AAO:0000729 xref: EMAPA:37803 {source="MA:th"} @@ -168807,8 +169053,8 @@ subset: vertebrate_core synonym: "involuntary muscle" EXACT [] synonym: "non-striated muscle" EXACT [] synonym: "smooth muscle" EXACT [] -synonym: "textus muscularis levis; textus muscularis nonstriatus" RELATED LATIN [Wikipedia:Smooth_muscle_tissue] -synonym: "textus muscularis nonstriatus" EXACT LATIN [FMA:14070, FMA:TA] +synonym: "textus muscularis levis; textus muscularis nonstriatus" RELATED OMO:0003011 [Wikipedia:Smooth_muscle_tissue] +synonym: "textus muscularis nonstriatus" EXACT OMO:0003011 [FMA:14070, FMA:TA] synonym: "visceral muscle" NARROW SENSU [] synonym: "visceral muscle tissue" NARROW SENSU [] xref: AAO:0010244 @@ -168915,7 +169161,7 @@ def: "In anatomy, the superior mesenteric vein (SMV) is a blood vessel that drai subset: human_reference_atlas subset: uberon_slim synonym: "upper mesenteric vein" RELATED [BTO:0002783] -synonym: "vena mesenterica superior" RELATED LATIN [Wikipedia:Superior_mesenteric_vein] +synonym: "vena mesenterica superior" RELATED OMO:0003011 [Wikipedia:Superior_mesenteric_vein] xref: BTO:0002783 xref: EHDAA2:0001951 xref: EHDAA:5414 @@ -168945,7 +169191,7 @@ def: "A vein that drains the pelvis and lower limbs into the inferior vena cava. subset: human_reference_atlas subset: uberon_slim synonym: "common iliac venous tree" EXACT [] -synonym: "vena iliaca communis" RELATED LATIN [Wikipedia:Common_iliac_vein] +synonym: "vena iliaca communis" RELATED OMO:0003011 [Wikipedia:Common_iliac_vein] xref: EMAPA:17874 xref: FMA:14333 xref: galen:CommonIliacVein @@ -168974,7 +169220,7 @@ subset: uberon_slim synonym: "kidney vein" EXACT [OBOL:automatic] synonym: "renal venous tree" EXACT [] synonym: "vein of kidney" EXACT [OBOL:automatic] -synonym: "venae renales" RELATED LATIN [Wikipedia:Renal_vein] +synonym: "venae renales" RELATED OMO:0003011 [Wikipedia:Renal_vein] xref: BTO:0002681 xref: EHDAA2:0001602 xref: EHDAA:8722 @@ -169056,8 +169302,8 @@ subset: vertebrate_core synonym: "hepatic veins" RELATED OMO:0003004 [] synonym: "liver vein" EXACT [OBOL:automatic] synonym: "vein of liver" EXACT [OBOL:automatic] -synonym: "vena hepatica" EXACT LATIN [] -synonym: "venae hepaticae" RELATED LATIN [Wikipedia:Hepatic_vein] +synonym: "vena hepatica" EXACT OMO:0003011 [] +synonym: "venae hepaticae" RELATED OMO:0003011 [Wikipedia:Hepatic_vein] xref: AAO:0010216 xref: EMAPA:19221 xref: FMA:14337 @@ -169096,9 +169342,9 @@ synonym: "testicle vein" EXACT [OBOL:automatic] synonym: "testicular venous tree" EXACT [Wikipedia:Testicular_vein] synonym: "vein of testicle" EXACT [OBOL:automatic] synonym: "vena tesicularis" RELATED [BTO:0002678] -synonym: "vena testicularis dextra" RELATED LATIN [Wikipedia:Testicular_vein] -synonym: "vena testicularis sinistra" RELATED LATIN [Wikipedia:Testicular_vein] -synonym: "venae spermaticae" RELATED LATIN [Wikipedia:Testicular_vein] +synonym: "vena testicularis dextra" RELATED OMO:0003011 [Wikipedia:Testicular_vein] +synonym: "vena testicularis sinistra" RELATED OMO:0003011 [Wikipedia:Testicular_vein] +synonym: "venae spermaticae" RELATED OMO:0003011 [Wikipedia:Testicular_vein] xref: BTO:0002678 xref: EMAPA:18647 xref: FMA:14344 @@ -169137,8 +169383,8 @@ synonym: "vein of female reproductive system gonada" EXACT [OBOL:automatic] synonym: "vein of gonad of female reproductive system" EXACT [OBOL:automatic] synonym: "vein of gonada of female reproductive system" EXACT [OBOL:automatic] synonym: "vein of ovary" EXACT [OBOL:automatic] -synonym: "vena ovarica dextra" RELATED LATIN [Wikipedia:Ovarian_vein] -synonym: "vena ovarica sinistra" RELATED LATIN [Wikipedia:Ovarian_vein] +synonym: "vena ovarica dextra" RELATED OMO:0003011 [Wikipedia:Ovarian_vein] +synonym: "vena ovarica sinistra" RELATED OMO:0003011 [Wikipedia:Ovarian_vein] xref: EMAPA:18644 xref: FMA:14346 xref: MA:0002186 @@ -169184,7 +169430,7 @@ def: "The tubular structure that conducts gall bladder contents from the gall bl subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "ductus cysticus" RELATED LATIN [Wikipedia:Cystic_duct] +synonym: "ductus cysticus" RELATED OMO:0003011 [Wikipedia:Cystic_duct] xref: EHDAA2:0000333 xref: EHDAA:3045 xref: EMAPA:16841 @@ -169277,8 +169523,8 @@ subset: uberon_slim synonym: "apex of caecum" RELATED [EMAPA:35140] synonym: "apex of cecum" RELATED [VHOG:0001306] synonym: "appendix" EXACT [] -synonym: "appendix vermiformis" EXACT LATIN [FMA:14542, FMA:TA] -synonym: "appendix vermiformis" RELATED LATIN [Wikipedia:Vermiform_appendix] +synonym: "appendix vermiformis" EXACT OMO:0003011 [FMA:14542, FMA:TA] +synonym: "appendix vermiformis" RELATED OMO:0003011 [Wikipedia:Vermiform_appendix] synonym: "caecal appendix" EXACT [] synonym: "cecal appendix" EXACT [] synonym: "vermix" BROAD [] @@ -169369,7 +169615,7 @@ def: "Section of colon which is distal to the cecum and proximal to the transver subset: efo_slim subset: human_reference_atlas subset: uberon_slim -synonym: "colon ascendens" EXACT LATIN [Wikipedia:Ascending_colon] +synonym: "colon ascendens" EXACT OMO:0003011 [Wikipedia:Ascending_colon] synonym: "spiral colon" RELATED SENSU [Wikipedia:Spiral_colon] xref: BTO:0000270 xref: CALOHA:TS-0057 @@ -169379,7 +169625,7 @@ xref: FMA:14545 xref: galen:AscendingColon xref: MA:0001541 xref: MAT:0000311 -xref: MESH:D044682 +xref: MESH:D044682 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: MIAA:0000311 xref: NCIT:C12265 xref: SCTID:362162009 @@ -169402,7 +169648,7 @@ def: "The proximal-distal subdivision of colon that runs transversely across the subset: efo_slim subset: human_reference_atlas subset: uberon_slim -synonym: "colon transversum" EXACT LATIN [Wikipedia:Transverse_colon] +synonym: "colon transversum" EXACT OMO:0003011 [Wikipedia:Transverse_colon] xref: BTO:0000272 xref: CALOHA:TS-2052 xref: EFO:0000844 @@ -169411,7 +169657,7 @@ xref: FMA:14546 xref: galen:TransverseColon xref: MA:0001543 xref: MAT:0000312 -xref: MESH:D044684 +xref: MESH:D044684 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: MIAA:0000312 xref: NCIT:C12385 xref: SCTID:362163004 @@ -169433,7 +169679,7 @@ def: "The portion of the colon between the left colic flexure and the sigmoid co subset: efo_slim subset: human_reference_atlas subset: uberon_slim -synonym: "colon descendens" EXACT LATIN [Wikipedia:Descending_colon] +synonym: "colon descendens" EXACT OMO:0003011 [Wikipedia:Descending_colon] xref: BTO:0000641 xref: CALOHA:TS-2010 xref: EFO:0000845 @@ -169442,7 +169688,7 @@ xref: FMA:14547 xref: galen:DescendingColon xref: MA:0001542 xref: MAT:0000313 -xref: MESH:D044683 +xref: MESH:D044683 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: MIAA:0000313 xref: NCIT:C12268 xref: SCTID:362165006 @@ -169464,7 +169710,7 @@ def: "The part of the large intestine that is closest to the rectum and anus. It subset: efo_slim subset: human_reference_atlas subset: uberon_slim -synonym: "colon sigmoideum" RELATED LATIN [Wikipedia:Sigmoid_colon] +synonym: "colon sigmoideum" RELATED OMO:0003011 [Wikipedia:Sigmoid_colon] synonym: "pelvic colon" RELATED [] synonym: "sigmoid colon" RELATED [] synonym: "sigmoid flexure" RELATED [] @@ -169535,7 +169781,7 @@ name: body of stomach namespace: uberon def: "The body of stomach is the part of the stomach that lies between the fundus above and the pyloric antrum below; its boundaries are poorly defined[GO]." [GO:0014845, Wikipedia:Body_of_stomach] subset: uberon_slim -synonym: "corpus gastricum" RELATED LATIN [BTO:0000505, Wikipedia:Body_of_stomach] +synonym: "corpus gastricum" RELATED OMO:0003011 [BTO:0000505, Wikipedia:Body_of_stomach] synonym: "corpus gastricum (ventriculare)" EXACT [] synonym: "corpus ventriculare" RELATED [BTO:0000505] synonym: "corpus ventriculi" RELATED [BTO:0000505] @@ -169562,7 +169808,7 @@ namespace: uberon alt_id: UBERON:0004712 def: "The part of the stomach attached to the esophagus. The cardia begins immediately distal to the z-line of the gastroeosphageal junction, where the squamous epithelium of the esophagus gives way to the columnar epithelium of the gastrointestinal tract[WP]." [BTO:0000198, Wikipedia:Cardia] subset: pheno_slim -synonym: "antrum cardiacum" RELATED LATIN [Wikipedia:Cardia] +synonym: "antrum cardiacum" RELATED OMO:0003011 [Wikipedia:Cardia] synonym: "cardiac antrum" RELATED [] synonym: "cardiac orifice" RELATED [Wikipedia:Cardia] synonym: "cardiac region" RELATED [Wikipedia:Cardia] @@ -169570,7 +169816,7 @@ synonym: "cardial orifice" RELATED [Wikipedia:Cardia] synonym: "cardial part of stomach" EXACT [] synonym: "gastric cardia" EXACT [] synonym: "pars cardiaca (gaster)" EXACT [] -synonym: "pars cardiaca gastricae" EXACT LATIN [FMA:14561, FMA:TA] +synonym: "pars cardiaca gastricae" EXACT OMO:0003011 [FMA:14561, FMA:TA] synonym: "stomach cardiac region" EXACT [MA:0001609] xref: BTO:0000198 xref: EMAPA:35811 @@ -169607,7 +169853,7 @@ synonym: "antrum" BROAD [] synonym: "antrum of stomach" EXACT [] synonym: "antrum of Willis" RELATED [BTO:0001732] synonym: "antrum pylori" RELATED [BTO:0001732] -synonym: "antrum pyloricum" RELATED LATIN [BTO:0001732, Wikipedia:Pyloric_antrum] +synonym: "antrum pyloricum" RELATED OMO:0003011 [BTO:0001732, Wikipedia:Pyloric_antrum] synonym: "gastric antrum" RELATED [BTO:0001732] synonym: "stomach antrum" RELATED [] synonym: "stomach pyloric antrum" EXACT [] @@ -169638,12 +169884,12 @@ namespace: uberon def: "The stomach tissue region surrounding and controlling the distal outlet of the stomach, which opens into the duodenum." [MGI:csmith, MP:0010785] subset: pheno_slim subset: uberon_slim -synonym: "pars pylorica" EXACT LATIN [] -synonym: "pars pylorica gastricae" EXACT LATIN [FMA:14581, FMA:TA] +synonym: "pars pylorica" EXACT OMO:0003011 [] +synonym: "pars pylorica gastricae" EXACT OMO:0003011 [FMA:14581, FMA:TA] synonym: "pyloric part of stomach" EXACT [] synonym: "pyloric region" EXACT [] synonym: "stomach pyloric region" EXACT [EHDAA2:0001580] -synonym: "valvula pylori" RELATED LATIN [Wikipedia:Pylorus] +synonym: "valvula pylori" RELATED OMO:0003011 [Wikipedia:Pylorus] xref: BTO:0001146 xref: EHDAA2:0001580 xref: EHDAA:4860 @@ -169804,6 +170050,7 @@ synonym: "biliary tract" RELATED [MA:0001273] xref: AAO:0011020 xref: EMAPA:35172 xref: FMA:14665 +xref: MESH:D001659 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} xref: SCTID:181267003 xref: UMLS:C0005423 {source="ncithesaurus:Biliary_Tract"} xref: Wikipedia:Biliary_tract @@ -169833,7 +170080,7 @@ subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "ductus choledochus" RELATED LATIN [Wikipedia:Common_bile_duct] +synonym: "ductus choledochus" RELATED OMO:0003011 [Wikipedia:Common_bile_duct] synonym: "ductus choledochus (biliaris)" EXACT [] xref: EHDAA2:0000303 xref: EHDAA:3981 @@ -169866,7 +170113,7 @@ namespace: uberon def: "Predominantly extrahepatic bile duct which is formed by the junction of the right and left hepatic ducts, which are predominantly intrahepatic, and, in turn, joins the cystic duct to form the common bile duct[GAID]. The common hepatic duct is the duct formed by the convergence of the right hepatic duct (which drains bile from the right functional lobe of the liver) and the left hepatic duct (which drains bile from the left functional lobe of the liver). The common hepatic duct then joins the cystic duct coming from the gallbladder to form the common bile duct[WP]." [Wikipedia:Common_hepatic_duct, ZFIN:curator] subset: pheno_slim subset: uberon_slim -synonym: "ductus hepaticus communis" RELATED LATIN [Wikipedia:Common_hepatic_duct] +synonym: "ductus hepaticus communis" RELATED OMO:0003011 [Wikipedia:Common_hepatic_duct] synonym: "hepatic duct" RELATED [] xref: EMAPA:19101 xref: FMA:14668 @@ -169893,7 +170140,7 @@ id: UBERON:0001176 name: right hepatic duct namespace: uberon def: "The duct that drains bile from the right half of the liver and joins the left hepatic duct to form the common hepatic duct." [http://www.medterms.com/script/main/art.asp?articlekey=26034] -synonym: "ductus hepaticus dexter" RELATED LATIN [] +synonym: "ductus hepaticus dexter" RELATED OMO:0003011 [] xref: EHDAA2:0001727 xref: EHDAA:3992 xref: EMAPA:32797 @@ -169915,7 +170162,7 @@ id: UBERON:0001177 name: left hepatic duct namespace: uberon def: "The duct that drains bile from the left half of the liver and joins the right hepatic duct to form the common hepatic duct." [http://www.medterms.com/script/main/art.asp?articlekey=26035] -synonym: "ductus hepaticus sinister" RELATED LATIN [] +synonym: "ductus hepaticus sinister" RELATED OMO:0003011 [] xref: EHDAA2:0000941 xref: EHDAA:3990 xref: EMAPA:32795 @@ -169960,8 +170207,8 @@ namespace: uberon def: "Anatomical cavity bounded by visceral and parietal peritoneum." [http://orcid.org/0000-0002-6601-2165, https://github.com/obophenotype/uberon/issues/86, Wikipedia:Peritoneal_cavity] subset: pheno_slim subset: uberon_slim -synonym: "cavitas peritonealis" RELATED LATIN [BTO:0001782, Wikipedia:Peritoneal_cavity] -synonym: "saccus serosus peritonei" RELATED LATIN [Wikipedia:Peritoneal_cavity] +synonym: "cavitas peritonealis" RELATED OMO:0003011 [BTO:0001782, Wikipedia:Peritoneal_cavity] +synonym: "saccus serosus peritonei" RELATED OMO:0003011 [Wikipedia:Peritoneal_cavity] xref: BTO:0001782 xref: EHDAA2:0001446 xref: EMAPA:16138 @@ -169995,7 +170242,7 @@ def: "Mesenteric artery that supplies the whole length of the small intestine ex subset: human_reference_atlas subset: pheno_slim subset: uberon_slim -synonym: "arteria mesenterica superior" RELATED LATIN [BTO:0002303, Wikipedia:Superior_mesenteric_artery] +synonym: "arteria mesenterica superior" RELATED OMO:0003011 [BTO:0002303, Wikipedia:Superior_mesenteric_artery] synonym: "superior mesenteric arterial tree" EXACT [] xref: BTO:0002303 xref: EHDAA2:0001949 @@ -170033,7 +170280,7 @@ def: "Mesenteric artery that supplies the large intestine from the left colic (o subset: human_reference_atlas subset: pheno_slim subset: uberon_slim -synonym: "arteria mesenterica inferior" RELATED LATIN [BTO:0002302, Wikipedia:Inferior_mesenteric_artery] +synonym: "arteria mesenterica inferior" RELATED OMO:0003011 [BTO:0002302, Wikipedia:Inferior_mesenteric_artery] synonym: "IMA" BROAD OMO:0003000 [] synonym: "inferior mesenteric arterial tree" EXACT [] xref: BTO:0002302 @@ -170073,7 +170320,7 @@ subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "arteria renalis" RELATED LATIN [Wikipedia:Renal_artery] +synonym: "arteria renalis" RELATED OMO:0003011 [Wikipedia:Renal_artery] synonym: "renal arterial tree" EXACT [] synonym: "renal arteries" RELATED OMO:0003004 [] xref: AAO:0010223 @@ -170162,7 +170409,7 @@ namespace: uberon def: "One of a pair of arteries that is a branch of the abdominal aorta that supplies blood to a male gonad." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Testicular_artery] subset: human_reference_atlas subset: uberon_slim -synonym: "arteria testicularis" RELATED LATIN [Wikipedia:Testicular_artery] +synonym: "arteria testicularis" RELATED OMO:0003011 [Wikipedia:Testicular_artery] synonym: "internal spermatic" RELATED [Wikipedia:Testicular_artery] synonym: "internal spermatic arteries" RELATED [Wikipedia:Testicular_artery] synonym: "internal spermatic artery" RELATED [Wikipedia:Testicular_artery] @@ -170233,7 +170480,7 @@ namespace: uberon def: "An artery that supplies an ovary." [OBOL:automatic] subset: human_reference_atlas subset: uberon_slim -synonym: "arteria ovarica" RELATED LATIN [Wikipedia:Ovarian_artery] +synonym: "arteria ovarica" RELATED OMO:0003011 [Wikipedia:Ovarian_artery] synonym: "ovarian arterial tree" EXACT [] xref: EMAPA:18620 xref: FMA:14761 @@ -170259,7 +170506,7 @@ def: "The common iliac arteries are two large arteries, about 4cm long in adults comment: See notes for parent class subset: human_reference_atlas subset: uberon_slim -synonym: "arteria iliaca communis" RELATED LATIN [Wikipedia:Common_iliac_artery] +synonym: "arteria iliaca communis" RELATED OMO:0003011 [Wikipedia:Common_iliac_artery] synonym: "common iliac arterial tree" EXACT [] xref: EHDAA2:0000311 xref: EHDAA:2553 @@ -170286,7 +170533,7 @@ subset: human_reference_atlas subset: uberon_slim subset: vertebrate_core synonym: "arteria hepatica" RELATED [BTO:0004307] -synonym: "arteria hepatica propria" EXACT LATIN [] +synonym: "arteria hepatica propria" EXACT OMO:0003011 [] xref: BTO:0004307 xref: EMAPA:17859 xref: FMA:14769 @@ -170315,8 +170562,8 @@ namespace: uberon def: "An artery that supplies the spleen." [http://orcid.org/0000-0002-6601-2165] subset: human_reference_atlas subset: uberon_slim -synonym: "arteria lienalis" RELATED LATIN [Wikipedia:Splenic_artery] -synonym: "arteria splenica" EXACT LATIN [Wikipedia:Splenic_artery] +synonym: "arteria lienalis" RELATED OMO:0003011 [Wikipedia:Splenic_artery] +synonym: "arteria splenica" EXACT OMO:0003011 [Wikipedia:Splenic_artery] synonym: "lienal artery" EXACT [MA:0001991] xref: EMAPA:19216 xref: FMA:14773 @@ -170348,7 +170595,7 @@ namespace: uberon def: "The middle colic artery is a branch of the superior mesenteric artery that mostly supplies the transverse colon. It arises just below the pancreas, and, passing downward and forward between the layers of the transverse mesocolon, divides into two branches: right and left. The right branch anastomoses with the right colic artery The left branch anastomoses with the left colic artery, a branch of the inferior mesenteric artery. The arches thus formed are placed about two fingers' breadth from the transverse colon, to which they distribute branches. [WP,unvetted]." [Wikipedia:Middle_colic_artery] subset: human_reference_atlas subset: uberon_slim -synonym: "arteria colica media" RELATED LATIN [Wikipedia:Middle_colic_artery] +synonym: "arteria colica media" RELATED OMO:0003011 [Wikipedia:Middle_colic_artery] xref: EMAPA:37106 {source="MA:th"} xref: FMA:14810 xref: galen:MiddleColicArtery @@ -170375,7 +170622,7 @@ namespace: uberon def: "The Ileocolic Artery is the lowest branch arising from the concavity of the superior mesenteric artery. It passes downward and to the right behind the peritoneum toward the right iliac fossa, where it divides into a superior and an inferior branch; the inferior anastomoses with the end of the superior mesenteric artery, the superior with the right colic artery. Supplies the cecum, ileum, and appendix. [WP,unvetted]." [Wikipedia:Ileocolic_artery] subset: human_reference_atlas subset: uberon_slim -synonym: "arteria ileocolica" RELATED LATIN [Wikipedia:Ileocolic_artery] +synonym: "arteria ileocolica" RELATED OMO:0003011 [Wikipedia:Ileocolic_artery] xref: EMAPA:37083 {source="MA:th"} xref: FMA:14815 xref: galen:IleocolicArtery @@ -170421,8 +170668,8 @@ synonym: "stomach mucosa of organ" EXACT [OBOL:automatic] synonym: "stomach mucous membrane" EXACT [OBOL:automatic] synonym: "stomach organ mucosa" EXACT [OBOL:automatic] synonym: "tunica mucosa (gaster)" EXACT [] -synonym: "tunica mucosa gastricae" EXACT LATIN [FMA:14907, FMA:TA] -synonym: "tunica mucosa gastris" RELATED LATIN [BTO:0001308, Wikipedia:Gastric_mucosa] +synonym: "tunica mucosa gastricae" EXACT OMO:0003011 [FMA:14907, FMA:TA] +synonym: "tunica mucosa gastris" RELATED OMO:0003011 [BTO:0001308, Wikipedia:Gastric_mucosa] synonym: "ventriculus mucosa" EXACT [OBOL:automatic] synonym: "ventriculus mucosa of organ" EXACT [OBOL:automatic] synonym: "ventriculus mucous membrane" EXACT [OBOL:automatic] @@ -170459,7 +170706,7 @@ synonym: "stomach submucosa" EXACT [] synonym: "submucosa of ventriculus" EXACT [OBOL:automatic] synonym: "submucous layer of stomach" RELATED [BTO:0002110] synonym: "tela submucosa (gaster)" EXACT [] -synonym: "tela submucosa gastricae" EXACT LATIN [FMA:14908, FMA:TA] +synonym: "tela submucosa gastricae" EXACT OMO:0003011 [FMA:14908, FMA:TA] synonym: "tela submucosa ventriculi" RELATED [BTO:0002110] synonym: "ventriculus submucosa" EXACT [OBOL:automatic] xref: BTO:0002110 @@ -170513,7 +170760,7 @@ synonym: "stomach serosa" EXACT [] synonym: "stomach wall serosa" EXACT [OBOL:automatic] synonym: "stomach wall serous membrane" EXACT [OBOL:automatic] synonym: "tunica serosa (gaster)" EXACT [] -synonym: "tunica serosa gastricae" EXACT LATIN [FMA:14914, FMA:TA] +synonym: "tunica serosa gastricae" EXACT OMO:0003011 [FMA:14914, FMA:TA] synonym: "ventriculus anatomical wall serosa" EXACT [OBOL:automatic] synonym: "ventriculus anatomical wall serous membrane" EXACT [OBOL:automatic] synonym: "ventriculus wall serosa" EXACT [OBOL:automatic] @@ -170585,7 +170832,7 @@ synonym: "small intestine mucosa of organ" EXACT [OBOL:automatic] synonym: "small intestine mucous membrane" EXACT [] synonym: "small intestine organ mucosa" EXACT [OBOL:automatic] synonym: "tunica mucosa (intestinum tenue)" EXACT [] -synonym: "tunica mucosa intestini tenuis" EXACT LATIN [FMA:14933, FMA:TA] +synonym: "tunica mucosa intestini tenuis" EXACT OMO:0003011 [FMA:14933, FMA:TA] xref: BTO:0001259 xref: CALOHA:TS-0941 xref: EMAPA:35780 @@ -170611,7 +170858,7 @@ synonym: "small intestinal submucosa" EXACT [] synonym: "small intestine submucosa" EXACT [] synonym: "submucosa of small bowel" EXACT [OBOL:automatic] synonym: "tela submucosa (intestinum tenue)" EXACT [] -synonym: "tela submucosa intestini tenuis" EXACT LATIN [BTO:0002112] +synonym: "tela submucosa intestini tenuis" EXACT OMO:0003011 [BTO:0002112] xref: BTO:0002112 xref: EMAPA:37564 {source="MA:th"} xref: FMA:14934 @@ -170640,7 +170887,7 @@ synonym: "small intestinal serosa" EXACT [] synonym: "small intestine serosa" EXACT [] synonym: "small intestine serous membrane" EXACT [OBOL:automatic] synonym: "tunica serosa (intestinum tenue)" EXACT [] -synonym: "tunica serosa intestini tenuis" EXACT LATIN [FMA:14938, FMA:TA] +synonym: "tunica serosa intestini tenuis" EXACT OMO:0003011 [FMA:14938, FMA:TA] synonym: "visceral peritoneum of small intestine" EXACT [] xref: EMAPA:37561 {source="MA:th"} xref: FMA:14938 @@ -170666,7 +170913,7 @@ synonym: "large intestine organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of organ of large intestine" EXACT [OBOL:automatic] synonym: "mucous membrane of large intestine" EXACT [] synonym: "organ mucosa of large intestine" EXACT [OBOL:automatic] -synonym: "tunica mucosa intestini crassi" EXACT LATIN [FMA:14969, FMA:TA] +synonym: "tunica mucosa intestini crassi" EXACT OMO:0003011 [FMA:14969, FMA:TA] xref: CALOHA:TS-2106 xref: EMAPA:35467 xref: FMA:14969 @@ -170687,7 +170934,7 @@ def: "A submucosa that is part of a large intestine [Automatically generated def synonym: "large intestinal submucosa" EXACT [] synonym: "large intestine submucosa" EXACT [] synonym: "submucous layer of large intestine" RELATED [BTO:0002111] -synonym: "tela submucosa intestini crassi" EXACT LATIN [FMA:14970, FMA:TA] +synonym: "tela submucosa intestini crassi" EXACT OMO:0003011 [FMA:14970, FMA:TA] xref: BTO:0002111 xref: EMAPA:37560 {source="MA:th"} xref: FMA:14970 @@ -170709,7 +170956,7 @@ synonym: "large intestine serosa" EXACT [] synonym: "large intestine serous membrane" EXACT [OBOL:automatic] synonym: "serous coat of large intestine" EXACT [] synonym: "serous membrane of large intestine" EXACT [OBOL:automatic] -synonym: "tunica serosa intestini crassi" EXACT LATIN [FMA:14975, FMA:TA] +synonym: "tunica serosa intestini crassi" EXACT OMO:0003011 [FMA:14975, FMA:TA] synonym: "visceral peritoneum of large intestine" EXACT [] xref: EMAPA:37557 {source="MA:th"} xref: FMA:14975 @@ -170733,7 +170980,7 @@ subset: pheno_slim subset: uberon_slim synonym: "aggregated lymphoid follicle of intestine" RELATED [] synonym: "aggregated lymphoid nodule" RELATED [] -synonym: "noduli lymphoidei aggregati" EXACT LATIN [] +synonym: "noduli lymphoidei aggregati" EXACT OMO:0003011 [] synonym: "Peyers gland" RELATED [BTO:0001784] synonym: "Peyers patch" RELATED [BTO:0001784] xref: BTO:0001784 @@ -170765,8 +171012,8 @@ subset: pheno_slim subset: uberon_slim synonym: "Brunner's gland" EXACT [FMA:15060] synonym: "gland of Brunner" EXACT [FMA:15060] -synonym: "glandula duodenales" RELATED LATIN [BTO:0002376] -synonym: "glandula duodenales Brunneri" RELATED LATIN [BTO:0002376] +synonym: "glandula duodenales" RELATED OMO:0003011 [BTO:0002376] +synonym: "glandula duodenales Brunneri" RELATED OMO:0003011 [BTO:0002376] synonym: "submucosal gland of duodenum" EXACT [] xref: BTO:0002376 xref: EMAPA:36522 @@ -170804,7 +171051,7 @@ synonym: "intestinal villi" EXACT OMO:0003004 [ZFA:0005125] synonym: "intestinal villus layer" RELATED [] synonym: "small intestine villus" RELATED [MA:0001563] synonym: "villi intestinales" EXACT OMO:0003004 [] -synonym: "villi intestinales" RELATED LATIN [Wikipedia:Intestinal_villus] +synonym: "villi intestinales" RELATED OMO:0003011 [Wikipedia:Intestinal_villus] synonym: "villus" EXACT [BTO:0003121] synonym: "villus intestinalis (intestinum tenue)" EXACT [FMA:15072] xref: BTO:0003121 @@ -170836,7 +171083,7 @@ def: "A blood vessel that drains blood from the large intestine that usually ter subset: human_reference_atlas subset: uberon_slim synonym: "lower mesenteric vein" RELATED [BTO:0002782] -synonym: "vena mesenterica inferior" RELATED LATIN [Wikipedia:Inferior_mesenteric_vein] +synonym: "vena mesenterica inferior" RELATED OMO:0003011 [Wikipedia:Inferior_mesenteric_vein] xref: BTO:0002782 xref: EHDAA2:0000819 xref: EHDAA:8712 @@ -170863,7 +171110,7 @@ name: jejunal vein namespace: uberon def: "A tributary of the superior mesenteric vein that drains the jejunum." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Jejunal_veins] subset: human_reference_atlas -synonym: "venae jejunales" RELATED LATIN [Wikipedia:Jejunal_veins] +synonym: "venae jejunales" RELATED OMO:0003011 [Wikipedia:Jejunal_veins] xref: EMAPA:37160 {source="MA:th"} xref: FMA:15402 xref: MA:0002153 @@ -170903,7 +171150,7 @@ namespace: uberon def: "The middle colic vein drains the transverse colon. It is a tributary of the superior mesenteric vein, and follows the path of its corresponding artery, the middle colic artery. [WP,unvetted]." [Wikipedia:Middle_colic_vein] subset: human_reference_atlas subset: uberon_slim -synonym: "vena colica media" RELATED LATIN [Wikipedia:Middle_colic_vein] +synonym: "vena colica media" RELATED OMO:0003011 [Wikipedia:Middle_colic_vein] synonym: "vena colica media (intermedia)" EXACT [] xref: EMAPA:37174 {source="MA:th"} xref: FMA:15406 @@ -170928,7 +171175,7 @@ namespace: uberon def: "The ileocolic vein is a vein which drains the ileum, colon, and cecum. [WP,unvetted]." [Wikipedia:Ileocolic_vein] subset: human_reference_atlas subset: uberon_slim -synonym: "vena ileocolica" RELATED LATIN [Wikipedia:Ileocolic_vein] +synonym: "vena ileocolica" RELATED OMO:0003011 [Wikipedia:Ileocolic_vein] xref: EMAPA:37150 {source="MA:th"} xref: FMA:15408 xref: MA:0002141 @@ -170997,7 +171244,7 @@ subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "kidney pelvis" EXACT [] -synonym: "p. renallis" RELATED LATIN [Wikipedia:Renal_pelvis] +synonym: "p. renallis" RELATED OMO:0003011 [Wikipedia:Renal_pelvis] synonym: "pelvis of ureter" EXACT [] synonym: "pyelum" RELATED [MP:0004194] xref: CALOHA:TS-2230 @@ -171032,7 +171279,7 @@ def: "Outer cortical portion of the kidney, between the renal capsule and the re subset: human_reference_atlas subset: pheno_slim subset: uberon_slim -synonym: "cortex renalis" EXACT LATIN [FMA:15581, FMA:TA] +synonym: "cortex renalis" EXACT OMO:0003011 [FMA:15581, FMA:TA] synonym: "kidney cortex" EXACT [] synonym: "renal cortex" EXACT [] xref: BTO:0001166 @@ -171100,8 +171347,8 @@ subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "corpusculum renale" EXACT LATIN [] -synonym: "corpusculum renis" RELATED LATIN [Wikipedia:Renal_corpuscle] +synonym: "corpusculum renale" EXACT OMO:0003011 [] +synonym: "corpusculum renis" RELATED OMO:0003011 [Wikipedia:Renal_corpuscle] synonym: "cortical renal corpuscle" RELATED [MA:0000376] synonym: "kidney corpuscle" RELATED [Wikipedia:Renal_corpuscle] synonym: "Malphigian corpuscle" EXACT MISSPELLING [MA:0000376] @@ -171142,8 +171389,8 @@ subset: vertebrate_core synonym: "Bowman's capsule" EXACT [http://www.gudmap.org/About/Tutorial/DevMUS.html#DMK_Nephron] synonym: "Bowman's capsule" RELATED [TAO:0005254] synonym: "Bowmans capsule" EXACT [KUPO:0001001] -synonym: "capsula glomerularis" EXACT LATIN [] -synonym: "capsula glomeruli" RELATED LATIN [] +synonym: "capsula glomerularis" EXACT OMO:0003011 [] +synonym: "capsula glomeruli" RELATED OMO:0003011 [] synonym: "Malphigian capsule" RELATED MISSPELLING [BTO:0002297] synonym: "Malpighian capsule" RELATED [UBERON:cjm] synonym: "Mueller capsule" RELATED [BTO:0002297] @@ -171233,7 +171480,7 @@ synonym: "junctional tube" RELATED [Wikipedia:Connecting_tubule] synonym: "kidney collecting duct" EXACT [] synonym: "kidney collecting tubule" RELATED [] synonym: "renal collecting tubule" EXACT [FMA:15628] -synonym: "tubulus renalis arcuatus" EXACT LATIN [Wikipedia:Connecting_tubule] +synonym: "tubulus renalis arcuatus" EXACT OMO:0003011 [Wikipedia:Connecting_tubule] synonym: "tubulus renalis colligens" EXACT [] synonym: "ureteric tree" RELATED [EMAPA:28407] xref: BTO:0000761 @@ -171261,7 +171508,7 @@ id: UBERON:0001233 name: right adrenal gland namespace: uberon def: "An adrenal gland that is in the right side of the abdomen." [OBOL:automatic] -synonym: "glandula suprarenalis dexter" EXACT LATIN [] +synonym: "glandula suprarenalis dexter" EXACT OMO:0003011 [] synonym: "right suprarenal gland" EXACT [] xref: EMAPA:37357 {source="MA:th"} xref: FMA:15629 @@ -171281,7 +171528,7 @@ id: UBERON:0001234 name: left adrenal gland namespace: uberon def: "An adrenal gland that is in the left side of the abdomen." [OBOL:automatic] -synonym: "glandula suprarenalis sinister" EXACT LATIN [] +synonym: "glandula suprarenalis sinister" EXACT OMO:0003011 [] synonym: "left suprarenal gland" EXACT [] xref: EMAPA:37356 {source="MA:th"} xref: FMA:15630 @@ -171306,7 +171553,7 @@ subset: pheno_slim subset: uberon_slim synonym: "adrenal gland cortex" EXACT [] synonym: "cortex (glandula suprarenalis)" EXACT [] -synonym: "cortex glandulae suprarenalis" RELATED LATIN [BTO:0000045, Wikipedia:Adrenal_cortex] +synonym: "cortex glandulae suprarenalis" RELATED OMO:0003011 [BTO:0000045, Wikipedia:Adrenal_cortex] synonym: "cortex of adrenal gland" EXACT [] synonym: "cortex of suprarenal gland" EXACT [] synonym: "suprarenal" RELATED [] @@ -171353,7 +171600,7 @@ synonym: "adrenal central medulla" RELATED [] synonym: "adrenal gland medulla" EXACT [] synonym: "chromaffin cells" RELATED [] synonym: "medulla (glandula suprarenalis)" EXACT [] -synonym: "medulla glandulae suprarenalis" EXACT LATIN [FMA:15633, FMA:TA] +synonym: "medulla glandulae suprarenalis" EXACT OMO:0003011 [FMA:15633, FMA:TA] synonym: "medulla of adrenal gland" EXACT [OBOL:automatic] synonym: "medulla of glandula suprarenalis" RELATED [BTO:0000049] synonym: "medulla of suprarenal gland" EXACT [] @@ -171576,7 +171823,7 @@ synonym: "proctodeum" RELATED [] xref: BTO:0001680 xref: CALOHA:TS-2005 xref: EV:0100082 -xref: FBbt:00047153 +xref: FBbt:00047153 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:15711 xref: GAID:312 xref: galen:Anus @@ -171628,7 +171875,7 @@ def: "A ligament that attaches the liver to the anterior body wall. It is a broa subset: uberon_slim synonym: "falciform ligament of liver" EXACT [] synonym: "ligamentum falciforme (hepatis)" EXACT [] -synonym: "ligamentum falciforme hepatis" EXACT LATIN [FMA:15823, FMA:TA] +synonym: "ligamentum falciforme hepatis" EXACT OMO:0003011 [FMA:15823, FMA:TA] xref: EHDAA2:0000499 xref: EHDAA:4856 xref: EMAPA:18288 @@ -171688,8 +171935,8 @@ def: "The parenchymatous tissue network of the spleen that consists of loose pla subset: human_reference_atlas subset: pheno_slim subset: uberon_slim -synonym: "pulpa rubra" EXACT LATIN [FMA:15844, FMA:TA] -synonym: "pulpa splenica" RELATED LATIN [Wikipedia:Red_pulp] +synonym: "pulpa rubra" EXACT OMO:0003011 [FMA:15844, FMA:TA] +synonym: "pulpa splenica" RELATED OMO:0003011 [Wikipedia:Red_pulp] synonym: "red pulp" EXACT [] synonym: "spleen red pulp" EXACT [] synonym: "splenic red pulp" EXACT [] @@ -171740,8 +171987,8 @@ name: adventitia of ureter namespace: uberon def: "An adventitia that is part of a ureter." [OBOL:automatic] synonym: "external adventitia of ureter" EXACT [] -synonym: "tunica adventitia (ureter)" EXACT LATIN [FMA:15892, FMA:TA] -synonym: "tunica adventitia ureteris" EXACT LATIN [FMA:15892, FMA:TA] +synonym: "tunica adventitia (ureter)" EXACT OMO:0003011 [FMA:15892, FMA:TA] +synonym: "tunica adventitia ureteris" EXACT OMO:0003011 [FMA:15892, FMA:TA] synonym: "ureter adventitia" EXACT [] synonym: "ureteral adventitia" EXACT [] xref: EMAPA:28114 @@ -171811,7 +172058,7 @@ subset: uberon_slim synonym: "bladder" BROAD [EHDAA2:0000174] synonym: "urocyst" RELATED [Wikipedia:Urinary_bladder] synonym: "vesica" RELATED [BTO:0001418] -synonym: "vesica urinaria" EXACT LATIN [Wikipedia:Urinary_bladder] +synonym: "vesica urinaria" EXACT OMO:0003011 [Wikipedia:Urinary_bladder] xref: AAO:0000623 xref: BTO:0001418 xref: CALOHA:TS-1090 @@ -171888,10 +172135,10 @@ synonym: "bladder trigone" EXACT [] synonym: "deep trigone" EXACT [] synonym: "dorsal bladder neck" RELATED [EMAPA:35174] synonym: "Lieutaud's trigone" EXACT [] -synonym: "musculus trigoni vesicae profundus" EXACT LATIN [FMA:15910, FMA:TA] +synonym: "musculus trigoni vesicae profundus" EXACT OMO:0003011 [FMA:15910, FMA:TA] synonym: "trigone of bladder" EXACT [] -synonym: "trigonum vesicae" EXACT LATIN [FMA:15910, FMA:TA] -synonym: "trigonum vesicae urinariae" RELATED LATIN [Wikipedia:Trigone_of_urinary_bladder] +synonym: "trigonum vesicae" EXACT OMO:0003011 [FMA:15910, FMA:TA] +synonym: "trigonum vesicae urinariae" RELATED OMO:0003011 [Wikipedia:Trigone_of_urinary_bladder] synonym: "urinary bladder trigone" EXACT [] synonym: "vesical trigone" EXACT [] xref: EMAPA:35174 @@ -171920,9 +172167,9 @@ def: "The constricted portion of the urinary bladder, formed by the meeting of i subset: pheno_slim subset: uberon_slim synonym: "bladder neck" EXACT [] -synonym: "cervix vesicae" EXACT LATIN [FMA:15912, FMA:TA] -synonym: "cervix vesicae urinariae" RELATED LATIN [Wikipedia:Neck_of_urinary_bladder] -synonym: "collum vesicae" EXACT LATIN [FMA:15912, FMA:TA] +synonym: "cervix vesicae" EXACT OMO:0003011 [FMA:15912, FMA:TA] +synonym: "cervix vesicae urinariae" RELATED OMO:0003011 [Wikipedia:Neck_of_urinary_bladder] +synonym: "collum vesicae" EXACT OMO:0003011 [FMA:15912, FMA:TA] synonym: "neck of bladder" EXACT [] synonym: "urinary bladder neck" EXACT [] synonym: "vesical neck" EXACT [] @@ -171955,8 +172202,8 @@ synonym: "bladder organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of bladder" EXACT [OBOL:automatic] synonym: "mucous membrane of bladder" EXACT [] synonym: "mucous membrane of urinary bladder" EXACT [] -synonym: "tunica mucosa (vesica urinaria)" EXACT LATIN [FMA:15928, FMA:TA] -synonym: "tunica mucosa vesicae" EXACT LATIN [FMA:15928, FMA:TA] +synonym: "tunica mucosa (vesica urinaria)" EXACT OMO:0003011 [FMA:15928, FMA:TA] +synonym: "tunica mucosa vesicae" EXACT OMO:0003011 [FMA:15928, FMA:TA] synonym: "tunica mucosa vesicae urinariae" EXACT [MP:MP] synonym: "urinary bladder mucosa" EXACT [] synonym: "urinary bladder mucous membrane" EXACT [OBOL:automatic] @@ -171987,8 +172234,8 @@ synonym: "serous coat of bladder" EXACT [] synonym: "serous coat of urinary bladder" EXACT [] synonym: "serous membrane of bladder" EXACT [OBOL:automatic] synonym: "serous membrane of urinary bladder" EXACT [OBOL:automatic] -synonym: "tunica serosa (vesica urinaria)" EXACT LATIN [FMA:15932, FMA:TA] -synonym: "tunica serosa vesicae" EXACT LATIN [FMA:15932, FMA:TA] +synonym: "tunica serosa (vesica urinaria)" EXACT OMO:0003011 [FMA:15932, FMA:TA] +synonym: "tunica serosa vesicae" EXACT OMO:0003011 [FMA:15932, FMA:TA] synonym: "urinary bladder serosa" EXACT [] synonym: "urinary bladder serous membrane" EXACT [OBOL:automatic] synonym: "visceral peritoneum of urinary bladder" EXACT [] @@ -172065,10 +172312,11 @@ namespace: uberon def: "The secretory units of the exocrine pancreas, where fluid containing digestive enzymes is produced; consists of a group of secretory cells surrounding a luminal space that connects to the pancreatic duct." [MP:0009145] subset: human_reference_atlas subset: pheno_slim -synonym: "acinus pancreaticus" EXACT LATIN [FMA:16011] +synonym: "acinus pancreaticus" EXACT OMO:0003011 [FMA:16011] synonym: "pancreas acinus" EXACT [] synonym: "pancreatic acinar" RELATED [] synonym: "pancreatic acini" RELATED OMO:0003004 [] +xref: BTO:0000028 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: EMAPA:35651 xref: FMA:16011 xref: MA:0002417 @@ -172186,6 +172434,7 @@ xref: BTO:0001031 xref: EMAPA:35683 xref: FMA:16515 xref: MA:0002531 +xref: MESH:D001202 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} xref: ncithesaurus:Peritoneal_Fluid xref: Wikipedia:Peritoneal_fluid is_a: UBERON:0007779 ! transudate @@ -172235,9 +172484,9 @@ synonym: "coxal bone" EXACT [FMA:16585] synonym: "hip bone" EXACT [FMA:16585] synonym: "innominate" BROAD [] synonym: "innominate bone" EXACT [FMA:16585] -synonym: "os coxa" EXACT LATIN [] -synonym: "os coxae" EXACT LATIN [FMA:16585, FMA:TA] -synonym: "os innominatum" RELATED LATIN [Wikipedia:Hip_bone] +synonym: "os coxa" EXACT OMO:0003011 [] +synonym: "os coxae" EXACT OMO:0003011 [FMA:16585, FMA:TA] +synonym: "os innominatum" RELATED OMO:0003011 [Wikipedia:Hip_bone] synonym: "pelvic bone" EXACT [FMA:16585] xref: FMA:16585 xref: GAID:205 @@ -172267,7 +172516,7 @@ synonym: "ilium bone" EXACT [] synonym: "illium" RELATED [] synonym: "os iliacum" EXACT [] synonym: "os ilii" EXACT [] -synonym: "os ilium" EXACT LATIN [FMA:16589, FMA:TA] +synonym: "os ilium" EXACT OMO:0003011 [FMA:16589, FMA:TA] xref: AAO:0000772 xref: CALOHA:TS-2200 xref: EFO:0003049 @@ -172309,7 +172558,7 @@ subset: pheno_slim subset: uberon_slim synonym: "ischial bone" EXACT [EMAPA:18727] synonym: "ischium bone" EXACT [] -synonym: "os ischii" RELATED LATIN [AAO:0000860, Wikipedia:Ischium] +synonym: "os ischii" RELATED OMO:0003011 [AAO:0000860, Wikipedia:Ischium] xref: AAO:0000860 xref: EMAPA:18727 xref: FMA:16592 @@ -172436,7 +172685,7 @@ subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "trias hepatica" EXACT [] -synonym: "trias hepatica" RELATED LATIN [Wikipedia:Portal_triad] +synonym: "trias hepatica" RELATED OMO:0003011 [Wikipedia:Portal_triad] xref: FMA:17523 xref: MA:0002499 xref: NCIT:C33342 @@ -172502,7 +172751,7 @@ synonym: "liver sinusoidal blood vessel" EXACT [OBOL:automatic] synonym: "sinusoid of liver" EXACT [OBOL:automatic] synonym: "sinusoidal blood vessel of liver" EXACT [OBOL:automatic] synonym: "vas capillare sinusoideum" EXACT [] -synonym: "vas sinusoideum" EXACT LATIN [Wikipedia:Hepatic_sinusoid] +synonym: "vas sinusoideum" EXACT OMO:0003011 [Wikipedia:Hepatic_sinusoid] xref: EHDAA2:0000999 xref: EMAPA:17365 xref: FMA:17543 @@ -172539,7 +172788,7 @@ synonym: "canal of Herring" EXACT [FMA:17545] synonym: "canals of Hering" RELATED OMO:0003004 [Wikipedia:Canals_of_Hering] synonym: "cholangiole" EXACT [FMA:17545] synonym: "duct of Herring" RELATED [Wikipedia:Canals_of_Hering] -synonym: "ductus interlobularis bilifer" EXACT LATIN [FMA:17545, FMA:TA] +synonym: "ductus interlobularis bilifer" EXACT OMO:0003011 [FMA:17545, FMA:TA] synonym: "intrahepatic bile ductule" RELATED [Wikipedia:Canals_of_Hering] xref: FMA:17545 xref: MA:0002669 @@ -172568,8 +172817,8 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "mature nephron" NARROW [EMAPA:28491] -synonym: "nephroneum" RELATED LATIN [Wikipedia:Nephron] -synonym: "tubulus renalis" RELATED LATIN [Wikipedia:Nephron] +synonym: "nephroneum" RELATED OMO:0003011 [Wikipedia:Nephron] +synonym: "tubulus renalis" RELATED OMO:0003011 [Wikipedia:Nephron] xref: BTO:0000924 xref: CALOHA:TS-1312 xref: EMAPA:28491 @@ -172647,8 +172896,8 @@ synonym: "PCT" RELATED [] synonym: "proximal convoluted renal tubule" EXACT [] synonym: "renal proximal convoluted tubule" RELATED [http://orcid.org/0000-0002-6601-2165] synonym: "tubulus contortus proximalis" EXACT [] -synonym: "tubulus contortus proximalis" RELATED LATIN [Wikipedia:Proximal_convoluted_tubule] -synonym: "tubulus convolutus proximalis" RELATED LATIN [] +synonym: "tubulus contortus proximalis" RELATED OMO:0003011 [Wikipedia:Proximal_convoluted_tubule] +synonym: "tubulus convolutus proximalis" RELATED OMO:0003011 [] xref: CALOHA:TS-2198 xref: EMAPA:28287 xref: EV:0100388 @@ -172678,7 +172927,7 @@ namespace: uberon def: "The section of the renal tubule in the kidney medulla with a hairpin bend; consists of a descending limb and an ascending limb, and is situated between the proximal convoluted tubule to the distal convoluted tubule; it functions to reabsorb water and ions from the urine." [MGI:csmith, MP:0004755] subset: pheno_slim subset: uberon_slim -synonym: "ansa nephroni" EXACT LATIN [Wikipedia:Loop_of_Henle] +synonym: "ansa nephroni" EXACT OMO:0003011 [Wikipedia:Loop_of_Henle] synonym: "Henle loop" EXACT [] synonym: "Henle's loop" EXACT [] xref: BTO:0004608 @@ -172784,7 +173033,7 @@ synonym: "thick ascending limb" EXACT [] synonym: "thick ascending limb of distal tubule" EXACT [FMA:17722] synonym: "thick ascending limb of Henle's loop" EXACT [] synonym: "tubulus rectus distalis" EXACT [FMA:17722] -synonym: "tubulus rectus distalis" RELATED LATIN [Wikipedia:Thick_ascending_limb_of_loop_of_Henle] +synonym: "tubulus rectus distalis" RELATED OMO:0003011 [Wikipedia:Thick_ascending_limb_of_loop_of_Henle] xref: EMAPA:28396 xref: EMAPA:29671 xref: EMAPA:35512 @@ -172810,8 +173059,8 @@ subset: uberon_slim synonym: "distal convoluted renal tubule" EXACT [] synonym: "second convoluted tubule" RELATED [] synonym: "tubulus contortus distalis" EXACT [] -synonym: "tubulus contortus distalis" RELATED LATIN [Wikipedia:Distal_convoluted_tubule] -synonym: "tubulus convolutus distalis" RELATED LATIN [] +synonym: "tubulus contortus distalis" RELATED OMO:0003011 [Wikipedia:Distal_convoluted_tubule] +synonym: "tubulus convolutus distalis" RELATED OMO:0003011 [] xref: EMAPA:28393 xref: EV:0100389 xref: FMA:17721 @@ -172843,8 +173092,8 @@ synonym: "outer zone of medulla of kidney" EXACT [] synonym: "outer zone of renal medulla" EXACT [] synonym: "renal outer medulla" EXACT [BTO:0001746] synonym: "set of outer region of renal pyramids" RELATED [FMA:17733] -synonym: "zona externa (medullaris renalis)" EXACT LATIN [FMA:17733, FMA:TA] -synonym: "zona externa medullae renalis" EXACT LATIN [FMA:17733, FMA:TA] +synonym: "zona externa (medullaris renalis)" EXACT OMO:0003011 [FMA:17733, FMA:TA] +synonym: "zona externa medullae renalis" EXACT OMO:0003011 [FMA:17733, FMA:TA] xref: BTO:0001746 xref: CALOHA:TS-0508 xref: EMAPA:28310 @@ -172867,8 +173116,8 @@ synonym: "inner zone of renal medulla" EXACT [] synonym: "kidney inner medulla" RELATED [BTO:0001745] synonym: "renal inner medulla" EXACT [BTO:0001745] synonym: "set of inner region of renal pyramids" EXACT [] -synonym: "zona interna (medullaris renalis)" EXACT LATIN [FMA:17734, FMA:TA] -synonym: "zona interna medullae renalis" EXACT LATIN [FMA:17734, FMA:TA] +synonym: "zona interna (medullaris renalis)" EXACT OMO:0003011 [FMA:17734, FMA:TA] +synonym: "zona interna medullae renalis" EXACT OMO:0003011 [FMA:17734, FMA:TA] xref: BTO:0001745 xref: CALOHA:TS-0506 xref: EMAPA:28349 @@ -172891,7 +173140,7 @@ subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "tunica mucosa (endometrium)" EXACT [FMA:17742] -synonym: "tunica mucosa uteri" EXACT LATIN [Wikipedia:Endometrium] +synonym: "tunica mucosa uteri" EXACT OMO:0003011 [Wikipedia:Endometrium] synonym: "uterine endometrium" EXACT [BTO:0001422] synonym: "uterine mucosa" RELATED [] synonym: "uterine mucous membrane" RELATED [BTO:0001422] @@ -172933,7 +173182,7 @@ def: "The smooth muscle coat of the uterus, which forms the main mass of the org subset: efo_slim subset: pheno_slim subset: uberon_slim -synonym: "tunica muscularis" RELATED LATIN [Wikipedia:Myometrium] +synonym: "tunica muscularis" RELATED OMO:0003011 [Wikipedia:Myometrium] synonym: "tunica muscularis (myometrium)" EXACT [] synonym: "uterine myometrium" RELATED [BTO:0000907] synonym: "uterine smooth muscle" RELATED [] @@ -172972,7 +173221,7 @@ synonym: "perimetrium" EXACT [Wikipedia:Perimetrium] synonym: "serous coat of uterus" EXACT [Wikipedia:Perimetrium] synonym: "serous membrane of uterus" EXACT [OBOL:automatic] synonym: "tunica serosa (perimetrium)" EXACT [] -synonym: "tunica serosa uteri" EXACT LATIN [FMA:17744, FMA:TA] +synonym: "tunica serosa uteri" EXACT OMO:0003011 [FMA:17744, FMA:TA] synonym: "uterine serosa" EXACT [] synonym: "uterus serosa" EXACT [] synonym: "uterus serous membrane" EXACT [OBOL:automatic] @@ -173147,8 +173396,8 @@ subset: vertebrate_core synonym: "egg follicle" RELATED [ZFA:0001110] synonym: "follicle of ovary" EXACT [] synonym: "follicle of ovary viewed macroscopically" EXACT [FMA:18640] -synonym: "folliculi ovarici primarii" RELATED LATIN [Wikipedia:Ovarian_follicle] -synonym: "folliculi ovarici vesiculosi" RELATED LATIN [Wikipedia:Ovarian_follicle] +synonym: "folliculi ovarici primarii" RELATED OMO:0003011 [Wikipedia:Ovarian_follicle] +synonym: "folliculi ovarici vesiculosi" RELATED OMO:0003011 [Wikipedia:Ovarian_follicle] synonym: "ovary follicle" EXACT [MA:0001707] xref: BTO:0000475 xref: CALOHA:TS-0726 @@ -173207,7 +173456,7 @@ namespace: uberon def: "The external iliac artery is a large artery in the pelvic region that carries blood to the lower limb. The external iliac artery is a paired artery, meaning there is one on each side of the body: a right external iliac artery and left external iliac artery. The external iliac artery is accompanied by the external iliac vein, which is located posterior to the artery. [WP,unvetted]." [Wikipedia:External_iliac_artery] subset: human_reference_atlas subset: uberon_slim -synonym: "arteria iliaca externa" RELATED LATIN [Wikipedia:External_iliac_artery] +synonym: "arteria iliaca externa" RELATED OMO:0003011 [Wikipedia:External_iliac_artery] xref: BTO:0004666 xref: EHDAA2:0000463 xref: EHDAA:4337 @@ -173231,7 +173480,7 @@ namespace: uberon def: "The internal iliac artery (formerly known as the hypogastric artery) is the main artery of the pelvis. [WP,unvetted]." [Wikipedia:Internal_iliac_artery] subset: human_reference_atlas subset: uberon_slim -synonym: "arteria iliaca interna" RELATED LATIN [Wikipedia:Internal_iliac_artery] +synonym: "arteria iliaca interna" RELATED OMO:0003011 [Wikipedia:Internal_iliac_artery] synonym: "hypogastric artery" RELATED [BTO:0004667] xref: BTO:0004667 xref: EMAPA:17860 @@ -173255,7 +173504,7 @@ def: "The umbilical artery is a paired artery (with one for each half of the bod subset: human_reference_atlas subset: pheno_slim subset: uberon_slim -synonym: "a. umbilicalis" RELATED LATIN [Wikipedia:Umbilical_artery] +synonym: "a. umbilicalis" RELATED OMO:0003011 [Wikipedia:Umbilical_artery] xref: BTO:0000841 xref: CALOHA:TS-1077 xref: EHDAA:1026 @@ -173286,9 +173535,9 @@ namespace: uberon def: "An artery that supplies blood to the lower urinary bladder." [http://orcid.org/0000-0002-6601-2165] subset: human_reference_atlas subset: uberon_slim -synonym: "arteria vesicali inferior" EXACT LATIN [Wikipedia:Inferior_vesical_artery] -synonym: "arteria vesicalis inferior" EXACT LATIN [Wikipedia:Inferior_vesical_artery] -synonym: "arteria vesicalis inferior" RELATED LATIN [Wikipedia:Inferior_vesical_artery] +synonym: "arteria vesicali inferior" EXACT OMO:0003011 [Wikipedia:Inferior_vesical_artery] +synonym: "arteria vesicalis inferior" EXACT OMO:0003011 [Wikipedia:Inferior_vesical_artery] +synonym: "arteria vesicalis inferior" RELATED OMO:0003011 [Wikipedia:Inferior_vesical_artery] xref: EMAPA:37089 {source="MA:th"} xref: FMA:18823 xref: MA:0002079 @@ -173314,9 +173563,9 @@ namespace: uberon def: "An artery that supplies blood to the upper urinary bladder." [http://orcid.org/0000-0002-6601-2165] subset: human_reference_atlas subset: uberon_slim -synonym: "arteria vesicali superior" EXACT LATIN [Wikipedia:Superior_vesical_artery] -synonym: "arteria vesicalis superior" EXACT LATIN [Wikipedia:Superior_vesical_artery] -synonym: "arteriae vesicales superiores" RELATED LATIN [Wikipedia:Superior_vesical_artery] +synonym: "arteria vesicali superior" EXACT OMO:0003011 [Wikipedia:Superior_vesical_artery] +synonym: "arteria vesicalis superior" EXACT OMO:0003011 [Wikipedia:Superior_vesical_artery] +synonym: "arteriae vesicales superiores" RELATED OMO:0003011 [Wikipedia:Superior_vesical_artery] xref: EMAPA:37123 {source="MA:th"} xref: FMA:18839 xref: MA:0002080 @@ -173340,7 +173589,7 @@ namespace: uberon def: "A large vein that connects the femoral vein to the common iliac vein. Their origin is at the inferior margin of the inguinal ligaments and they terminate when they join the internal iliac veins (to form the common iliac veins). Both external iliac veins are accompanied along their course by external iliac arteries. [WP,modified]." [Wikipedia:External_iliac_vein] subset: human_reference_atlas subset: uberon_slim -synonym: "vena iliaca externa" RELATED LATIN [Wikipedia:External_iliac_vein] +synonym: "vena iliaca externa" RELATED OMO:0003011 [Wikipedia:External_iliac_vein] xref: EHDAA2:0000464 xref: EMAPA:37144 {source="MA:th"} xref: FMA:18883 @@ -173365,8 +173614,8 @@ def: "A vein that begins near the upper part of the greater sciatic foramen, pas subset: human_reference_atlas subset: uberon_slim synonym: "hypogastric vein" RELATED [MA:0002139, Wikipedia:Internal_iliac_vein] -synonym: "v. hypogastrica" RELATED LATIN [Wikipedia:Internal_iliac_vein] -synonym: "v. iliaca interna" RELATED LATIN [Wikipedia:Internal_iliac_vein] +synonym: "v. hypogastrica" RELATED OMO:0003011 [Wikipedia:Internal_iliac_vein] +synonym: "v. iliaca interna" RELATED OMO:0003011 [Wikipedia:Internal_iliac_vein] xref: EHDAA2:0000874 xref: EMAPA:37148 {source="MA:th"} xref: FMA:18884 @@ -173434,7 +173683,7 @@ subset: pheno_slim subset: uberon_slim synonym: "ischiadic nerve" RELATED [Wikipedia:Sciatic_nerve] synonym: "ischiatic nerve" RELATED [Wikipedia:Sciatic_nerve] -synonym: "nervus ischiadicus" RELATED LATIN [BTO:0001221, Wikipedia:Sciatic_nerve] +synonym: "nervus ischiadicus" RELATED OMO:0003011 [BTO:0001221, Wikipedia:Sciatic_nerve] synonym: "nervus sciaticus" RELATED [BTO:0001221] xref: BIRNLEX:1133 xref: BTO:0001221 @@ -173467,7 +173716,7 @@ namespace: uberon def: "The tibial nerve is a branch of the sciatic nerve. The tibial nerve passes through the popliteal fossa to pass below the arch of soleus. In the popliteal fossa the nerve gives off branches to gastrocnemius, popliteus, soleus and plantaris muscles, an articular branch to the knee joint, and a cutaneous branch that will become the sural nerve. The sural nerve is joined by fibres from the common peroneal nerve and runs down the calf to supply the lateral side of the foot. Below the soleus muscle the nerve lies close to the tibia and supplies the tibialis posterior, the flexor digitorum longus and the flexor hallucis longus. The nerve passes into the foot running posterior to the medial malleolus. Here it is bound down by the flexor retinaculum in company with the posterior tibial artery. [WP,unvetted]." [Wikipedia:Tibial_nerve] subset: uberon_slim synonym: "medial popliteal nerve" EXACT [] -synonym: "n. tibialis" RELATED LATIN [Wikipedia:Tibial_nerve] +synonym: "n. tibialis" RELATED OMO:0003011 [Wikipedia:Tibial_nerve] xref: EMAPA:36512 xref: FMA:19035 xref: GAID:854 @@ -173532,7 +173781,7 @@ subset: human_reference_atlas subset: uberon_slim synonym: "pampiniform venous plexus" EXACT [] synonym: "plexus of veins of fascia of prostate" EXACT [] -synonym: "plexus venosus pampiniformis" EXACT LATIN [FMA:19607, FMA:TA] +synonym: "plexus venosus pampiniformis" EXACT OMO:0003011 [FMA:19607, FMA:TA] synonym: "venous plexus of fascia of prostate" EXACT [] synonym: "venous plexus of fascia of prostate gland" EXACT [] xref: EMAPA:37385 {source="MA:th"} @@ -173576,12 +173825,12 @@ subset: pheno_slim subset: uberon_slim synonym: "foreskin" RELATED [FMA:19639] synonym: "penile prepuce" EXACT [FMA:19639] -synonym: "praeputium" RELATED LATIN [Wikipedia:Foreskin] +synonym: "praeputium" RELATED OMO:0003011 [Wikipedia:Foreskin] synonym: "prepuce" BROAD [MA:0000407, Wikipedia:Foreskin] synonym: "prepuce of male" EXACT [EMAPA:18989] -synonym: "prepucium" RELATED LATIN [Wikipedia:Foreskin] +synonym: "prepucium" RELATED OMO:0003011 [Wikipedia:Foreskin] synonym: "preputium" BROAD [HP:0100587] -synonym: "preputium penis" EXACT LATIN [FMA:19639, FMA:TA] +synonym: "preputium penis" EXACT OMO:0003011 [FMA:19639, FMA:TA] xref: BTO:0001113 xref: CALOHA:TS-0383 xref: EFO:0001664 @@ -173656,7 +173905,7 @@ subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "male prostatic urethra" EXACT [MP:0011777] -synonym: "pars prostatica urethrae" EXACT LATIN [MP:0011777, Wikipedia:Prostatic_urethra] +synonym: "pars prostatica urethrae" EXACT OMO:0003011 [MP:0011777, Wikipedia:Prostatic_urethra] synonym: "pars prostatica urethrae" RELATED [BTO:0003163] synonym: "prostatic part of male urethra" EXACT [MP:0011777] synonym: "prostatic part of urethra" EXACT [] @@ -173712,7 +173961,7 @@ synonym: "seminiferous cord" EXACT [EMAPA:18685] synonym: "seminiferous tubule" EXACT [] synonym: "testis - seminiferous tubule" EXACT [] synonym: "tubuli seminiferi" EXACT [] -synonym: "tubuli seminiferi" RELATED LATIN [Wikipedia:Seminiferous_tubule] +synonym: "tubuli seminiferi" RELATED OMO:0003011 [Wikipedia:Seminiferous_tubule] xref: AAO:0010399 xref: BTO:0001235 xref: CALOHA:TS-1239 @@ -173783,7 +174032,7 @@ subset: pheno_slim subset: uberon_slim synonym: "adipocytus unigutturalis" EXACT [] synonym: "textus adiposus albus" EXACT [] -synonym: "textus adiposus albus" RELATED LATIN [Wikipedia:White_adipose_tissue] +synonym: "textus adiposus albus" RELATED OMO:0003011 [Wikipedia:White_adipose_tissue] synonym: "unilocular adipose tissue" EXACT [] synonym: "white fat" EXACT [] xref: BTO:0001456 @@ -173793,7 +174042,7 @@ xref: EMAPA:35926 xref: FMA:20117 xref: MA:0000058 xref: MAT:0000199 -xref: MESH:D052436 +xref: MESH:D052436 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: MIAA:0000199 xref: NCIT:C33889 xref: UMLS:C1704223 {source="ncithesaurus:White_Adipose_Tissue"} @@ -173817,7 +174066,7 @@ synonym: "BAT" RELATED OMO:0003000 [Wikipedia:Brown_adipose_tissue] synonym: "brown fat" EXACT [] synonym: "multilocular adipose tissue" EXACT [] synonym: "textus adiposus fuscus" EXACT [] -synonym: "textus adiposus fuscus" RELATED LATIN [Wikipedia:Brown_adipose_tissue] +synonym: "textus adiposus fuscus" RELATED OMO:0003011 [Wikipedia:Brown_adipose_tissue] xref: BTO:0000156 xref: CALOHA:TS-0099 xref: EFO:0000812 @@ -173851,7 +174100,7 @@ subset: pheno_slim subset: uberon_slim synonym: "lachrymal sac" EXACT [] synonym: "lacrymal sac" EXACT [] -synonym: "saccus lacrimalis" EXACT LATIN [Wikipedia:Lacrimal_sac] +synonym: "saccus lacrimalis" EXACT OMO:0003011 [Wikipedia:Lacrimal_sac] xref: FMA:20289 xref: MA:0001298 xref: NCIT:C32909 @@ -173960,7 +174209,7 @@ namespace: uberon def: "The medial circumflex femoral artery (internal circumflex artery, medial femoral circumflex artery) is an artery in the upper thigh that helps supply blood to the neck of the femur. [WP,unvetted]." [Wikipedia:Medial_circumflex_femoral_artery] subset: human_reference_atlas subset: uberon_slim -synonym: "arteria circumflexa femoris medialis" RELATED LATIN [Wikipedia:Medial_circumflex_femoral_artery] +synonym: "arteria circumflexa femoris medialis" RELATED OMO:0003011 [Wikipedia:Medial_circumflex_femoral_artery] synonym: "medial femoral circumflex artery" EXACT [] xref: EMAPA:37670 {source="MA:th"} xref: FMA:20799 @@ -174023,7 +174272,7 @@ namespace: uberon def: "In the human body, the femoral vein is a blood vessel that accompanies the femoral artery in the femoral sheath. It begins at the adductor canal (also known as Hunter's canal) and is a continuation of the popliteal vein. It ends at the inferior margin of the inguinal ligament, where it becomes the external iliac vein. [WP,unvetted]." [Wikipedia:Femoral_vein] subset: human_reference_atlas subset: uberon_slim -synonym: "vena femoralis" RELATED LATIN [Wikipedia:Femoral_vein] +synonym: "vena femoralis" RELATED OMO:0003011 [Wikipedia:Femoral_vein] xref: AAO:0010237 xref: EMAPA:17876 xref: FMA:21185 @@ -174051,7 +174300,7 @@ subset: uberon_slim synonym: "greater saphenous vein" EXACT [] synonym: "large saphenous vein" RELATED [BTO:0003271] synonym: "long saphenous vein" RELATED [] -synonym: "vena saphena magna" RELATED LATIN [Wikipedia:Great_saphenous_vein] +synonym: "vena saphena magna" RELATED OMO:0003011 [Wikipedia:Great_saphenous_vein] xref: BTO:0003271 xref: EMAPA:37147 {source="MA:th"} xref: FMA:21376 @@ -174136,7 +174385,7 @@ subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "excitable area" RELATED [BTO:0004348] -synonym: "gyrus precentralis" RELATED LATIN [Wikipedia:Primary_motor_cortex] +synonym: "gyrus precentralis" RELATED OMO:0003011 [Wikipedia:Primary_motor_cortex] synonym: "motor area" RELATED [BTO:0004348] synonym: "motor cortex" EXACT [FMA:224854] synonym: "prefrontal gyrus" RELATED [MP:0000798, Wikipedia:Primary_motor_cortex] @@ -174179,7 +174428,7 @@ namespace: uberon def: "Artery that supplies the axilla." [http://orcid.org/0000-0002-6601-2165] subset: human_reference_atlas subset: uberon_slim -synonym: "arteria axillaris" EXACT LATIN [Wikipedia:Axillary_artery] +synonym: "arteria axillaris" EXACT OMO:0003011 [Wikipedia:Axillary_artery] synonym: "axillary part of subclavian artery" EXACT [FMA:22654] synonym: "axillary part of trunk of subclavian artery" EXACT [] xref: EMAPA:18749 @@ -174210,7 +174459,7 @@ namespace: uberon def: "The subscapular artery, the largest branch of the axillary artery, arises at the lower border of the Subscapularis, which it follows to the inferior angle of the scapula, where it anastomoses with the lateral thoracic and intercostal arteries and with the descending branch of the transverse cervical, and ends in the neighboring muscles. About 4 cm. from its origin it gives off two branches, first the scapular circumflex artery and then the thoracodorsal artery. [WP,unvetted]." [Wikipedia:Subscapular_artery] subset: human_reference_atlas subset: uberon_slim -synonym: "arteria subscapularis" RELATED LATIN [Wikipedia:Subscapular_artery] +synonym: "arteria subscapularis" RELATED OMO:0003011 [Wikipedia:Subscapular_artery] xref: EMAPA:37116 {source="MA:th"} xref: FMA:22677 xref: MA:0002050 @@ -174335,7 +174584,7 @@ def: "An organism subdivision that includes the pectoral girdle skeleton and ass subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "cingulum membri superioris" EXACT LATIN [FMA:23217, FMA:TA] +synonym: "cingulum membri superioris" EXACT OMO:0003011 [FMA:23217, FMA:TA] synonym: "cingulum membri superioris" NARROW [FMA:TA] synonym: "girdle - pectoral" EXACT [] synonym: "pectoral girdle" RELATED [] @@ -174589,13 +174838,14 @@ synonym: "compact bone tissue" EXACT [] synonym: "cortical bone" EXACT [] synonym: "cortical bone tissue" EXACT [] synonym: "cortical region of bone" EXACT [] -synonym: "substantia compacta" EXACT LATIN [FMA:24018, FMA:TA] +synonym: "substantia compacta" EXACT OMO:0003011 [FMA:24018, FMA:TA] synonym: "substantia compacta (pars ossea)" EXACT [] -synonym: "substantia corticalis" EXACT LATIN [FMA:24018, FMA:TA] +synonym: "substantia corticalis" EXACT OMO:0003011 [FMA:24018, FMA:TA] xref: EMAPA:35250 xref: FMA:24018 xref: galen:CorticalBone xref: MA:0001461 +xref: MESH:D000071538 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} xref: NCIT:C52714 xref: SCTID:361728003 xref: UMLS:C0222661 {source="ncithesaurus:Cortical_Bone"} @@ -174614,7 +174864,7 @@ synonym: "bones of upper limb" EXACT [] synonym: "fore limb skeleton" EXACT [] synonym: "forelimb skeleton" EXACT [VHOG:0001256] synonym: "free upper limb skeleton" EXACT [FMA:24142] -synonym: "ossa membri superioris" EXACT LATIN [FMA:24139, FMA:TA] +synonym: "ossa membri superioris" EXACT OMO:0003011 [FMA:24139, FMA:TA] synonym: "pectoral limb skeleton" EXACT [] synonym: "set of bones of upper limb" EXACT [] synonym: "skeleton of forelimb" EXACT [] @@ -174657,7 +174907,7 @@ synonym: "hind limb skeleton" EXACT [XAO:0003062] synonym: "hind-limb skeleton" EXACT [VSAO:0000152] synonym: "hindlimb skeleton" EXACT [VHOG:0001255] synonym: "lower limb skeleton" EXACT [] -synonym: "ossa membri inferioris" EXACT LATIN [FMA:24140, FMA:TA] +synonym: "ossa membri inferioris" EXACT OMO:0003011 [FMA:24140, FMA:TA] synonym: "set of bones of lower limb" EXACT [] synonym: "skeleton of free lower limb" EXACT [FMA:24144] synonym: "skeleton of lower limb" EXACT [FMA:24140] @@ -174697,7 +174947,7 @@ synonym: "hand skeleton" EXACT [FMA:24159] synonym: "manual skeleton" EXACT [] synonym: "manus" RELATED [VSAO:0005020, VSAO:NI] synonym: "manus skeleton" EXACT [] -synonym: "ossa manus" EXACT LATIN [FMA:24159, FMA:TA] +synonym: "ossa manus" EXACT OMO:0003011 [FMA:24159, FMA:TA] synonym: "set of bones of hand" EXACT [FMA:24159] synonym: "skeleton of hand" EXACT [FMA:24159] xref: EHDAA2:0002227 @@ -174723,9 +174973,9 @@ subset: pheno_slim subset: uberon_slim synonym: "anterolateral part of thorax" EXACT [] synonym: "front of thorax" EXACT [] -synonym: "pectus" EXACT LATIN [FMA:24816, FMA:TA] +synonym: "pectus" EXACT OMO:0003011 [FMA:24816, FMA:TA] synonym: "thoracic body wall" RELATED [MA:0000031] -synonym: "thorax" RELATED LATIN [FMA:9576, Wikipedia:Chest] +synonym: "thorax" RELATED OMO:0003011 [FMA:9576, Wikipedia:Chest] synonym: "ventral part of thoracic region" EXACT [] xref: BTO:0001368 xref: CALOHA:TS-1039 @@ -174945,7 +175195,7 @@ namespace: uberon def: "A subdivision of the head that has as parts the layers deep to the surface of the anterior surface, including the mouth, eyes, and nose (when present). In vertebrates, this includes the facial skeleton and structures superficial to the facial skeleton (cheeks, mouth, eyeballs, skin of face, etc)." [http://orcid.org/0000-0002-6601-2165] subset: pheno_slim subset: uberon_slim -synonym: "facia/facies" RELATED LATIN [Wikipedia:Face] +synonym: "facia/facies" RELATED OMO:0003011 [Wikipedia:Face] synonym: "visage" RELATED [BTO:0003369] xref: BTO:0003369 xref: CALOHA:TS-2216 @@ -175049,7 +175299,7 @@ def: "The part of the forelimb extending from the shoulder to the autopod[cjm]." subset: efo_slim subset: pheno_slim subset: uberon_slim -synonym: "brachium" RELATED LATIN [Wikipedia:Arm] +synonym: "brachium" RELATED OMO:0003011 [Wikipedia:Arm] synonym: "upper extremity" RELATED [MESH:A01.378.800] xref: BTO:0001435 xref: CALOHA:TS-2204 @@ -175081,7 +175331,7 @@ def: "The elbow is the region surrounding the elbow-joint-the ginglymus or hinge subset: efo_slim subset: pheno_slim subset: uberon_slim -synonym: "articulatio cubiti" RELATED LATIN [Wikipedia:Elbow] +synonym: "articulatio cubiti" RELATED OMO:0003011 [Wikipedia:Elbow] synonym: "cubital region" EXACT [] synonym: "elbow limb segment" EXACT [] synonym: "elbow region" EXACT [] @@ -175113,7 +175363,7 @@ def: "The hip region is located lateral to the gluteal region (i.e. the buttock) subset: efo_slim subset: pheno_slim subset: uberon_slim -synonym: "coxa" RELATED LATIN [Wikipedia:Hip] +synonym: "coxa" RELATED OMO:0003011 [Wikipedia:Hip] synonym: "hip region" EXACT [FMA:24964] synonym: "regio coxae" EXACT [FMA:24964] xref: BTO:0001457 @@ -175180,7 +175430,7 @@ subset: uberon_slim synonym: "digit of foot" EXACT [] synonym: "digit of terminal segment of lower limb" EXACT [OBOL:automatic] synonym: "digiti pedis" EXACT OMO:0003004 [FMA:70664, FMA:TA] -synonym: "digiti pedis" RELATED LATIN [Wikipedia:Toe] +synonym: "digiti pedis" RELATED OMO:0003011 [Wikipedia:Toe] synonym: "digitipedis" RELATED [BTO:0002348] synonym: "digitus pedis" EXACT [] synonym: "foot digit" EXACT [MA:0000048] @@ -175217,7 +175467,7 @@ def: "A subdivision of the pectoral complex consisting of the structures in the subset: efo_slim subset: pheno_slim subset: uberon_slim -synonym: "articulatio humeri" RELATED LATIN [Wikipedia:Shoulder] +synonym: "articulatio humeri" RELATED OMO:0003011 [Wikipedia:Shoulder] synonym: "shoulder region" EXACT [] xref: CALOHA:TS-2229 xref: EFO:0003068 @@ -175273,7 +175523,7 @@ name: sternoclavicular joint namespace: uberon def: "The sternoclavicular articulation is a double arthrodial joint composed of two portions separated by an articular disc. The parts entering into its formation are the sternal end of the clavicle, the upper and lateral part of the manubrium sterni, and the cartilage of the first rib, visible from the outside as the suprasternal notch. The articular surface of the clavicle is much larger than that of the sternum, and is invested with a layer of cartilage, which is considerably thicker than that on the latter bone. The ligaments of this joint are: Articular capsule Anterior sternoclavicular ligament Posterior sternoclavicular ligament Interclavicular ligament Costoclavicular ligament Articular disk [WP,unvetted]." [Wikipedia:Sternoclavicular_articulation] subset: uberon_slim -synonym: "articulatio sternoclavicularis" RELATED LATIN [Wikipedia:Sternoclavicular_articulation] +synonym: "articulatio sternoclavicularis" RELATED OMO:0003011 [Wikipedia:Sternoclavicular_articulation] synonym: "sterno clavicular joint" EXACT [] synonym: "sternoclavicular" BROAD [Wikipedia:Sternoclavicular_articulation] synonym: "sternoclavicular articulation" EXACT [Wikipedia:Sternoclavicular_articulation] @@ -175301,7 +175551,7 @@ name: glenohumeral joint namespace: uberon def: "The glenohumeral joint, commonly known as the shoulder joint, is a multiaxial synovial ball and socket joint and involves articulation between the glenoid fossa of the scapula (shoulder blade) and the head of the humerus (upper arm bone). [WP,unvetted]." [Wikipedia:Glenohumeral_joint] subset: uberon_slim -synonym: "articulatio humeri" EXACT LATIN [FMA:25912, FMA:TA] +synonym: "articulatio humeri" EXACT OMO:0003011 [FMA:25912, FMA:TA] synonym: "humeral joint" EXACT [FMA:25912] synonym: "humeroscapular joint" RELATED [Wikipedia:Glenohumeral_joint] synonym: "joint of shoulder" BROAD [OBOL:automatic] @@ -175357,7 +175607,7 @@ name: vaginal venous plexus namespace: uberon def: "The vaginal plexuses are placed at the sides of the vagina; they communicate with the uterine, vesical, and hemorrhoidal plexuses, and are drained by the vaginal veins, one on either side, into the hypogastric veins. [WP,unvetted]." [Wikipedia:Vaginal_venous_plexus] subset: uberon_slim -synonym: "plexus venosus vaginalis" RELATED LATIN [Wikipedia:Vaginal_venous_plexus] +synonym: "plexus venosus vaginalis" RELATED OMO:0003011 [Wikipedia:Vaginal_venous_plexus] synonym: "venous vaginal plexus" EXACT [] xref: EMAPA:37801 {source="MA:th"} xref: FMA:29713 @@ -175382,7 +175632,7 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "lymph vessel" EXACT [] -synonym: "vas lymphaticum" RELATED LATIN [Wikipedia:Lymphatic_vessel] +synonym: "vas lymphaticum" RELATED OMO:0003011 [Wikipedia:Lymphatic_vessel] xref: AAO:0011005 xref: BTO:0000752 xref: CALOHA:TS-2102 @@ -175391,7 +175641,7 @@ xref: EMAPA:35532 xref: FMA:30315 xref: MA:0000138 xref: MAT:0000443 -xref: MESH:D042601 +xref: MESH:D042601 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: NCIT:C33038 xref: SCTID:279089004 xref: TAO:0005105 @@ -175485,7 +175735,7 @@ synonym: "deltoideus" RELATED [Wikipedia:Deltoid_muscle] synonym: "deltoideus muscle" RELATED [Wikipedia:Deltoid_muscle] synonym: "m. deltoideus" EXACT [AAO:0010716] synonym: "musculus deltoideus" EXACT [Wikipedia:Deltoid_muscle] -synonym: "musculus deltoideus" RELATED LATIN [Wikipedia:Deltoid_muscle] +synonym: "musculus deltoideus" RELATED OMO:0003011 [Wikipedia:Deltoid_muscle] xref: AAO:0010716 xref: EFO:0001412 xref: EHDAA2:0000339 @@ -175525,7 +175775,7 @@ namespace: uberon def: "A sesamoid element that is composed of bone tissue." [http://orcid.org/0000-0002-6601-2165] comment: Sesamoids are often endochondral replacement elements and in addition to bone tissue, may also be composed of articular cartilage, fibrocartilage, hyaline cartilage, and calcified cartilage.[VSAO] subset: uberon_slim -synonym: "ossa sesamoidea" EXACT LATIN [Wikipedia:Sesamoid_bone] +synonym: "ossa sesamoidea" EXACT OMO:0003011 [Wikipedia:Sesamoid_bone] synonym: "sesamoid" BROAD [] xref: AEO:0000086 xref: EHDAA2:0003086 @@ -175606,8 +175856,8 @@ namespace: uberon def: "An articular capsule (or joint capsule) is an envelope surrounding a synovial joint. [WP,unvetted]." [Wikipedia:Articular_capsule] subset: organ_slim subset: uberon_slim -synonym: "capsula articularis" EXACT LATIN [FMA:34836, FMA:TA] -synonym: "capsulae articulares" RELATED LATIN [Wikipedia:Articular_capsule] +synonym: "capsula articularis" EXACT OMO:0003011 [FMA:34836, FMA:TA] +synonym: "capsulae articulares" RELATED OMO:0003011 [Wikipedia:Articular_capsule] synonym: "fibrous capsule of joint" EXACT [] synonym: "joint capsule" EXACT [] synonym: "joint fibrous capsule" EXACT [] @@ -175641,7 +175891,7 @@ subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim -synonym: "articulatio genus" RELATED LATIN [Wikipedia:Knee] +synonym: "articulatio genus" RELATED OMO:0003011 [Wikipedia:Knee] synonym: "joint of knee" EXACT [OBOL:automatic] xref: EFO:0001957 xref: EMAPA:19137 @@ -175675,7 +175925,7 @@ name: pes joint namespace: uberon def: "A skeletal joint that is part of a pes [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim -synonym: "articulationes pedis" EXACT LATIN [FMA:71349, FMA:TA] +synonym: "articulationes pedis" EXACT OMO:0003011 [FMA:71349, FMA:TA] synonym: "foot joint" EXACT [] synonym: "hind limb autopod joint" EXACT [OBOL:automatic] synonym: "joint of pes" EXACT [] @@ -175742,7 +175992,7 @@ name: manus joint namespace: uberon def: "A skeletal joint that is part of a manus (hand) [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim -synonym: "articulationes manus" EXACT LATIN [FMA:71345, FMA:TA] +synonym: "articulationes manus" EXACT OMO:0003011 [FMA:71345, FMA:TA] synonym: "hand joint" EXACT [] synonym: "joint of hand" EXACT [] synonym: "joint of manus" EXACT [] @@ -175768,7 +176018,7 @@ namespace: uberon def: "A joint that connects the forelimb zeugopod and stylopod skeletons[Obol]." [https://orcid.org/0000-0002-6601-2165, Wikipedia:Elbow] subset: pheno_slim subset: uberon_slim -synonym: "articulatio cubiti" EXACT LATIN [] +synonym: "articulatio cubiti" EXACT OMO:0003011 [] synonym: "cubital region joint" EXACT [OBOL:automatic] synonym: "joint of cubital region" EXACT [OBOL:automatic] synonym: "joint of elbow" EXACT [OBOL:automatic] @@ -175834,7 +176084,7 @@ subset: uberon_slim synonym: "auxillery nerve" RELATED [Wikipedia:Axillary_nerve] synonym: "circumflex humeral nerve" EXACT [] synonym: "circumflex nerve" RELATED [Wikipedia:Axillary_nerve] -synonym: "nervus axillaris" RELATED LATIN [Wikipedia:Axillary_nerve] +synonym: "nervus axillaris" RELATED OMO:0003011 [Wikipedia:Axillary_nerve] xref: EMAPA:18802 xref: FMA:37072 xref: MA:0001166 @@ -175892,10 +176142,10 @@ def: "The ascending aorta is the portion of the aorta in a two-pass circulatory subset: human_reference_atlas subset: pheno_slim subset: uberon_slim -synonym: "aorta ascendens" RELATED LATIN [Wikipedia:Ascending_aorta] +synonym: "aorta ascendens" RELATED OMO:0003011 [Wikipedia:Ascending_aorta] synonym: "ascending thoracic aorta" EXACT [EMAPA:17014] synonym: "pars ascendens aortae" EXACT [] -synonym: "pars ascendens aortae" RELATED LATIN [Wikipedia:Ascending_aorta] +synonym: "pars ascendens aortae" RELATED OMO:0003011 [Wikipedia:Ascending_aorta] xref: EHDAA2:0000147 xref: EHDAA:9828 xref: EMAPA:17014 @@ -176017,7 +176267,7 @@ subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "aortic arch" RELATED [FMA:3768] -synonym: "arcus aortae" EXACT LATIN [FMA:3768, FMA:TA] +synonym: "arcus aortae" EXACT OMO:0003011 [FMA:3768, FMA:TA] synonym: "thoracic aorta" RELATED [GAID:471] xref: BTO:0000157 xref: EFO:0002526 @@ -176133,9 +176383,9 @@ def: "The descending aorta is the portion of the aorta in a two-pass circulatory subset: human_reference_atlas subset: pheno_slim subset: uberon_slim -synonym: "aorta descendens" RELATED LATIN [Wikipedia:Descending_aorta] +synonym: "aorta descendens" RELATED OMO:0003011 [Wikipedia:Descending_aorta] synonym: "pars descendens aortae" EXACT [FMA:3784] -synonym: "pars descendens aortae" RELATED LATIN [Wikipedia:Descending_aorta] +synonym: "pars descendens aortae" RELATED OMO:0003011 [Wikipedia:Descending_aorta] xref: EMAPA:18606 xref: FMA:3784 xref: MA:0002571 @@ -176163,9 +176413,9 @@ def: "The part of the aorta that extends from the origin at the heart to the dia subset: efo_slim subset: pheno_slim subset: uberon_slim -synonym: "aorta thoracalis" RELATED LATIN [Wikipedia:Thoracic_aorta] -synonym: "aorta thoracica" EXACT LATIN [FMA:3786, FMA:TA] -synonym: "pars thoracica aortae" RELATED LATIN [Wikipedia:Thoracic_aorta] +synonym: "aorta thoracalis" RELATED OMO:0003011 [Wikipedia:Thoracic_aorta] +synonym: "aorta thoracica" EXACT OMO:0003011 [FMA:3786, FMA:TA] +synonym: "pars thoracica aortae" RELATED OMO:0003011 [Wikipedia:Thoracic_aorta] synonym: "thoracic part of aorta" EXACT [] xref: BTO:0000157 xref: EFO:0002525 @@ -176197,10 +176447,10 @@ subset: pheno_slim subset: uberon_slim synonym: "abdominal part of aorta" EXACT [FMA:3789] synonym: "abdominal part of aorta" RELATED [BTO:0002976] -synonym: "aorta abdominalis" RELATED LATIN [BTO:0002976, Wikipedia:Abdominal_aorta] +synonym: "aorta abdominalis" RELATED OMO:0003011 [BTO:0002976, Wikipedia:Abdominal_aorta] synonym: "descending abdominal aorta" EXACT [FMA:3789] synonym: "pars abdominalis aortae" EXACT [FMA:3789] -synonym: "pars abdominalis aortae" RELATED LATIN [BTO:0002976, Wikipedia:Abdominal_aorta] +synonym: "pars abdominalis aortae" RELATED OMO:0003011 [BTO:0002976, Wikipedia:Abdominal_aorta] xref: BTO:0002976 xref: EFO:0002524 xref: EMAPA:17856 @@ -176299,8 +176549,8 @@ subset: uberon_slim synonym: "brachiocephalic trunk" EXACT [MA:0001922] synonym: "innominate" BROAD [Wikipedia:Brachiocephalic_artery] synonym: "innominate artery" EXACT [Wikipedia:Brachiocephalic_artery] -synonym: "truncus brachiocephalicus" EXACT LATIN [FMA:3932, FMA:TA] -synonym: "truncus brachiocephalicus" RELATED LATIN [Wikipedia:Brachiocephalic_artery] +synonym: "truncus brachiocephalicus" EXACT OMO:0003011 [FMA:3932, FMA:TA] +synonym: "truncus brachiocephalicus" RELATED OMO:0003011 [Wikipedia:Brachiocephalic_artery] xref: EFO:0002550 xref: EHDAA2:0000835 xref: EMAPA:17615 @@ -176330,7 +176580,7 @@ def: "A bilaterally paired branched artery that originates from the aortic arche subset: human_reference_atlas subset: pheno_slim subset: uberon_slim -synonym: "a. carotis communis" RELATED LATIN [Wikipedia:Common_carotid_artery] +synonym: "a. carotis communis" RELATED OMO:0003011 [Wikipedia:Common_carotid_artery] synonym: "carotid artery" BROAD [FMA:3939] synonym: "carotid artery system" EXACT [EHDAA2:0000217] synonym: "common carotid artery" EXACT INCONSISTENT [FMA:3939] @@ -176392,7 +176642,7 @@ subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "arteria carotis interna" RELATED LATIN [Wikipedia:Internal_carotid_artery] +synonym: "arteria carotis interna" RELATED OMO:0003011 [Wikipedia:Internal_carotid_artery] synonym: "cranial carotid artery" EXACT [ZFA:0005081] synonym: "ICA" RELATED OMO:0003000 [] synonym: "internal carotid" EXACT [AAO:0010219] @@ -176437,8 +176687,8 @@ subset: pheno_slim subset: uberon_slim subset: unverified_taxonomic_grouping subset: vertebrate_core -synonym: "arteria subclavia" EXACT LATIN [XAO:0000365] -synonym: "arteria subclavia" RELATED LATIN [Wikipedia:Subclavian_artery] +synonym: "arteria subclavia" EXACT OMO:0003011 [XAO:0000365] +synonym: "arteria subclavia" RELATED OMO:0003011 [Wikipedia:Subclavian_artery] synonym: "arterial tree of upper limb" EXACT [] synonym: "PA" RELATED OMO:0003000 [] synonym: "pectoral artery" EXACT [] @@ -176480,7 +176730,7 @@ def: "The subclavian artery that supplies the right pectoral appendage." [http:/ subset: human_reference_atlas subset: pheno_slim subset: uberon_slim -synonym: "arteria subclavia dextra" EXACT LATIN [FMA:3953, FMA:TA] +synonym: "arteria subclavia dextra" EXACT OMO:0003011 [FMA:3953, FMA:TA] xref: EHDAA2:0004514 xref: EMAPA:37384 {source="MA:th"} xref: FMA:3953 @@ -176532,7 +176782,7 @@ namespace: uberon def: "The popliteal vein course runs alongside the popliteal artery but carries the blood from the knee joint and muscles in the thigh and calf back to the heart. Its origin is defined by the junction of the posterior tibial vein and anterior tibial vein. It drains the peroneal vein before reaching the knee joint and turns into the femoral vein when leaving the adductor canal (also known as Hunter's canal). The popliteal artery extends from the femoral artery behind the popliteal fossa which is the space behind the knee. [WP,unvetted]." [Wikipedia:Popliteal_vein] subset: human_reference_atlas subset: uberon_slim -synonym: "vena poplitea" RELATED LATIN [Wikipedia:Popliteal_vein] +synonym: "vena poplitea" RELATED OMO:0003011 [Wikipedia:Popliteal_vein] xref: EMAPA:37181 {source="MA:th"} xref: FMA:44327 xref: GAID:537 @@ -176556,7 +176806,7 @@ namespace: uberon def: "A vein of the lower limb that carries blood from the anterior compartment of the leg to the popliteal vein which is forms when it joins with the posterior tibial vein. Like most deep veins, the anterior tibial vein is accompanied by an artery of the same name, the anterior tibial artery, along its course. [WP,unvetted]." [Wikipedia:Anterior_tibial_vein] subset: human_reference_atlas subset: uberon_slim -synonym: "venae tibiales anteriores" RELATED LATIN [Wikipedia:Anterior_tibial_vein] +synonym: "venae tibiales anteriores" RELATED OMO:0003011 [Wikipedia:Anterior_tibial_vein] xref: EMAPA:37135 {source="MA:th"} xref: FMA:44331 xref: galen:AnteriorTibialVein @@ -176580,7 +176830,7 @@ subset: human_reference_atlas subset: uberon_slim synonym: "lesser saphenous vein" EXACT [] synonym: "short saphenous vein" EXACT [] -synonym: "vena saphena parva" EXACT LATIN [Wikipedia:Small_saphenous_vein] +synonym: "vena saphena parva" EXACT OMO:0003011 [Wikipedia:Small_saphenous_vein] xref: BTO:0003272 xref: EMAPA:37187 {source="MA:th"} xref: FMA:44333 @@ -176602,7 +176852,7 @@ namespace: uberon def: "The dorsal metatarsal veins are veins which drain the metatarsus of the foot. [WP,unvetted]." [Wikipedia:Dorsal_metatarsal_veins] subset: human_reference_atlas synonym: "metatarsal vein" EXACT [] -synonym: "venae metatarsales dorsales" RELATED LATIN [Wikipedia:Dorsal_metatarsal_veins] +synonym: "venae metatarsales dorsales" RELATED OMO:0003011 [Wikipedia:Dorsal_metatarsal_veins] xref: EMAPA:37143 {source="MA:th"} xref: FMA:44377 xref: MA:0002105 @@ -176624,7 +176874,7 @@ def: "A continuation of the Dorsal venous arch of the foot and is the origin of subset: human_reference_atlas synonym: "medial marginal vein of foot" EXACT [] synonym: "vena marginalis medialis" EXACT [] -synonym: "vena marginalis medialis pedis" EXACT LATIN [FMA:44420, FMA:TA] +synonym: "vena marginalis medialis pedis" EXACT OMO:0003011 [FMA:44420, FMA:TA] xref: EMAPA:37170 {source="MA:th"} xref: FMA:44420 xref: MA:0002171 @@ -176698,10 +176948,11 @@ xref: BTO:0000545 xref: EHDAA2:0000726 xref: EHDAA:518 xref: EMAPA:16247 -xref: FBbt:00003125 +xref: FBbt:00003125 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:45615 xref: galen:AlimentaryTract xref: MA:0000917 +xref: MESH:D041981 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} xref: NCIT:C34082 xref: TAO:0000112 xref: TGMA:0001819 @@ -176728,6 +176979,7 @@ id: UBERON:0001556 name: lower urinary tract namespace: uberon def: "Subdivision of urinary system which consists of the urinary bladder and the urethra." [FMA:45659] +subset: human_reference_atlas subset: pheno_slim subset: uberon_slim xref: FMA:45659 @@ -176738,6 +176990,7 @@ is_a: UBERON:0011216 ! organ system subdivision relationship: has_part UBERON:0000057 ! urethra relationship: has_part UBERON:0001255 ! urinary bladder relationship: part_of UBERON:0001008 ! renal system +relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: UBERON:0001557 @@ -176971,7 +177224,7 @@ synonym: "muscle of face" EXACT [FMA:46751] synonym: "muscle of facil expression" RELATED [Wikipedia:Facial_muscles] synonym: "muscle organ of face" EXACT [OBOL:automatic] synonym: "muscles of facial expression" RELATED [Wikipedia:Facial_muscles] -synonym: "musculi faciei" RELATED LATIN [Wikipedia:Facial_muscles] +synonym: "musculi faciei" RELATED OMO:0003011 [Wikipedia:Facial_muscles] xref: FMA:46751 xref: GAID:143 xref: MA:0003160 @@ -177005,8 +177258,8 @@ synonym: "fila olfactoria" RELATED [BTO:0003648] synonym: "first cranial nerve" EXACT [] synonym: "nerve I" RELATED [NeuroNames:32] synonym: "nerve of smell" RELATED [BTO:0003648] -synonym: "nervus olfactorius" RELATED LATIN [BTO:0003648, Wikipedia:Olfactory_nerve] -synonym: "nervus olfactorius [i]" EXACT LATIN [FMA:46787, FMA:TA] +synonym: "nervus olfactorius" RELATED OMO:0003011 [BTO:0003648, Wikipedia:Olfactory_nerve] +synonym: "nervus olfactorius [i]" EXACT OMO:0003011 [FMA:46787, FMA:TA] synonym: "olfactoria fila" RELATED [NeuroNames:32] synonym: "olfactory fila" RELATED [BTO:0003648] synonym: "olfactory I" EXACT [EHDAA2:0001293] @@ -177060,7 +177313,7 @@ def: "The subclavian artery that supplies the left pectoral appendage." [http:// subset: human_reference_atlas subset: pheno_slim subset: uberon_slim -synonym: "arteria subclavia (sinistra)" EXACT LATIN [FMA:4694, FMA:TA] +synonym: "arteria subclavia (sinistra)" EXACT OMO:0003011 [FMA:4694, FMA:TA] xref: EMAPA:37100 {source="MA:th"} xref: FMA:4694 xref: MA:0002046 @@ -177092,8 +177345,8 @@ synonym: "cranial vena cava" RELATED [VHOG:0001195] synonym: "precava" RELATED [] synonym: "superior caval vein" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "superior vena cava" EXACT [FMA:4720] -synonym: "vena cava superior" RELATED LATIN [BTO:0002683, Wikipedia:Superior_vena_cava] -synonym: "vena maxima" RELATED LATIN [Wikipedia:Superior_vena_cava] +synonym: "vena cava superior" RELATED OMO:0003011 [BTO:0002683, Wikipedia:Superior_vena_cava] +synonym: "vena maxima" RELATED OMO:0003011 [Wikipedia:Superior_vena_cava] xref: BTO:0002683 xref: EHDAA2:0001962 xref: EHDAA:8726 @@ -177127,7 +177380,7 @@ subset: human_reference_atlas subset: uberon_slim synonym: "internal jugular" EXACT [EHDAA2:0000877] synonym: "internal jugular venous tree" EXACT [] -synonym: "vena jugularis interna" RELATED LATIN [Wikipedia:Internal_jugular_vein] +synonym: "vena jugularis interna" RELATED OMO:0003011 [Wikipedia:Internal_jugular_vein] xref: AAO:0010236 xref: EHDAA2:0000877 xref: EHDAA:5407 @@ -177157,7 +177410,7 @@ def: "The subclavian vein is a paired large vein, one on either side of the body subset: human_reference_atlas subset: uberon_slim synonym: "subclavian venous tree" EXACT [] -synonym: "vena subclavia" EXACT LATIN [Wikipedia:Subclavian_vein] +synonym: "vena subclavia" EXACT OMO:0003011 [Wikipedia:Subclavian_vein] xref: AAO:0010510 xref: EHDAA2:0001934 xref: EHDAA:4455 @@ -177185,8 +177438,8 @@ namespace: uberon def: "A vein that drains blood from the thymus." [http://orcid.org/0000-0002-6601-2165] subset: human_reference_atlas synonym: "thymic tributary of brachiocephalic vein" EXACT [] -synonym: "vena thymica" EXACT LATIN [Wikipedia:Thymic_veins] -synonym: "venae thymicae" RELATED LATIN [Wikipedia:Thymic_veins] +synonym: "vena thymica" EXACT OMO:0003011 [Wikipedia:Thymic_veins] +synonym: "venae thymicae" RELATED OMO:0003011 [Wikipedia:Thymic_veins] xref: EMAPA:36325 xref: FMA:4747 xref: MA:0002246 @@ -177228,8 +177481,8 @@ name: venous plexus namespace: uberon def: "A congregation of multiple veins." [Wikipedia:Venous_plexus] subset: uberon_slim -synonym: "plexus venosus" RELATED LATIN [Wikipedia:Venous_plexus] -synonym: "rete venosum" RELATED LATIN [Wikipedia:Venous_plexus] +synonym: "plexus venosus" RELATED OMO:0003011 [Wikipedia:Venous_plexus] +synonym: "rete venosum" RELATED OMO:0003011 [Wikipedia:Venous_plexus] synonym: "venous network" EXACT [] xref: EMAPA:36327 xref: FMA:4767 @@ -177253,7 +177506,7 @@ subset: pheno_slim subset: uberon_slim synonym: "Bowman`s muscles" RELATED [BTO:0000654] synonym: "ciliaris" RELATED [Wikipedia:Ciliary_muscle] -synonym: "musculus ciliaris" RELATED LATIN [Wikipedia:Ciliary_muscle] +synonym: "musculus ciliaris" RELATED OMO:0003011 [Wikipedia:Ciliary_muscle] synonym: "musculus ciliarus" EXACT [BTO:0000654] xref: BTO:0000654 xref: EMAPA:35240 @@ -177274,7 +177527,6 @@ property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/2/28/Gr id: UBERON:0001606 name: muscle of iris namespace: uberon -def: "." [Wikipedia:Iris_muscle] subset: uberon_slim synonym: "iris muscle" EXACT [] synonym: "iris muscle organ" EXACT [OBOL:automatic] @@ -177305,7 +177557,7 @@ synonym: "iris constrictor muscle" RELATED [Wikipedia:Iris_sphincter_muscle] synonym: "iris sphincter" RELATED [Wikipedia:Iris_sphincter_muscle] synonym: "iris sphincter muscle" EXACT [BTO:0000656] synonym: "M. sphincter pupillae" EXACT [] -synonym: "m. sphincter pupillae" RELATED LATIN [Wikipedia:Iris_sphincter_muscle] +synonym: "m. sphincter pupillae" RELATED OMO:0003011 [Wikipedia:Iris_sphincter_muscle] synonym: "musculus sphincter pupillae" EXACT [BTO:0000656] synonym: "pupillary constrictor muscle" RELATED [Wikipedia:Iris_sphincter_muscle] synonym: "pupillary sphincter" RELATED [Wikipedia:Iris_sphincter_muscle] @@ -177351,8 +177603,8 @@ synonym: "dilator pupillae muscle" EXACT [Wikipedia:Iris_dilator_muscle] synonym: "dilator pupillae muscle" RELATED [BTO:0001371] synonym: "iris dilator" RELATED [Wikipedia:Iris_dilator_muscle] synonym: "iris dilator muscle" EXACT [BTO:0001371] -synonym: "musculus dilatator pupillae" EXACT LATIN [FMA:49158, FMA:TA] -synonym: "musculus dilatator pupillae" RELATED LATIN [Wikipedia:Iris_dilator_muscle] +synonym: "musculus dilatator pupillae" EXACT OMO:0003011 [FMA:49158, FMA:TA] +synonym: "musculus dilatator pupillae" RELATED OMO:0003011 [Wikipedia:Iris_dilator_muscle] synonym: "musculus dilator pupillae" RELATED [BTO:0001371] synonym: "pupil dilator" RELATED [Wikipedia:Iris_dilator_muscle] synonym: "pupil dilator muscle" RELATED [Wikipedia:Iris_dilator_muscle] @@ -177387,7 +177639,7 @@ namespace: uberon def: "The lingual artery arises from the external carotid between the superior thyroid and facial artery[WP]." [Wikipedia:Lingual_artery] subset: human_reference_atlas subset: uberon_slim -synonym: "arteria lingualis" RELATED LATIN [Wikipedia:Lingual_artery] +synonym: "arteria lingualis" RELATED OMO:0003011 [Wikipedia:Lingual_artery] synonym: "lingual branch of external carotid artery" EXACT [] xref: AAO:0010492 xref: EMAPA:36324 @@ -177415,7 +177667,7 @@ namespace: uberon def: "A branch of the external carotid artery that supplies structures of the face. [WP,unvetted]." [Wikipedia:Facial_artery] subset: human_reference_atlas subset: uberon_slim -synonym: "arteria maxillaris externa" RELATED LATIN [Wikipedia:Facial_artery] +synonym: "arteria maxillaris externa" RELATED OMO:0003011 [Wikipedia:Facial_artery] synonym: "external maxillary artery" RELATED [] xref: EMAPA:19213 xref: FMA:49549 @@ -177439,7 +177691,7 @@ namespace: uberon def: "The occipital artery arises opposite the facial artery, its path is below the posterior belly of digastric to the occipital region. This artery supplies blood to the back of the scalp and sterno-mastoid muscles. Other muscles it supplies are deep muscles in the back and neck. [WP,unvetted]." [Wikipedia:Occipital_artery] subset: human_reference_atlas subset: uberon_slim -synonym: "arteria occipitalis" RELATED LATIN [Wikipedia:Occipital_artery] +synonym: "arteria occipitalis" RELATED OMO:0003011 [Wikipedia:Occipital_artery] xref: EMAPA:37672 {source="MA:th"} xref: FMA:49586 xref: MA:0002009 @@ -177464,7 +177716,7 @@ namespace: uberon def: "An artery that supplies deep structures of the face. It comes just out behind the neck of the mandible. [WP,unvetted]." [Wikipedia:Maxillary_artery] subset: human_reference_atlas subset: uberon_slim -synonym: "arteria maxillaris" RELATED LATIN [Wikipedia:Maxillary_artery] +synonym: "arteria maxillaris" RELATED OMO:0003011 [Wikipedia:Maxillary_artery] synonym: "internal maxillary artery" RELATED [] xref: EHDAA2:0001069 xref: EHDAA:7357 @@ -177493,7 +177745,7 @@ namespace: uberon def: "The ophthalmic artery is a branch of the internal carotid artery which supplies branches to supply the eye and other structures in the orbit. It enters the orbit together with the Optic nerve through the Optic foramen/canal. [WP,modified]." [Wikipedia:Ophthalmic_artery] subset: human_reference_atlas subset: uberon_slim -synonym: "arteria ophthalmica" RELATED LATIN [Wikipedia:Ophthalmic_artery] +synonym: "arteria ophthalmica" RELATED OMO:0003011 [Wikipedia:Ophthalmic_artery] synonym: "opthalmic artery" RELATED [Wikipedia:Ophthalmic_artery] xref: AAO:0010497 xref: EHDAA2:0001300 @@ -177553,7 +177805,7 @@ namespace: uberon def: "The lacrimal artery arises close to the optic foramen, and is one of the largest branches derived from the ophthalmic artery: not infrequently it is given off before the artery enters the orbit. It accompanies the lacrimal nerve along the upper border of the Lateral Rectus, supplies the lacrimal gland. [WP,unvetted]." [Wikipedia:Lacrimal_artery] subset: human_reference_atlas subset: uberon_slim -synonym: "a. lacrimalis" RELATED LATIN [Wikipedia:Lacrimal_artery] +synonym: "a. lacrimalis" RELATED OMO:0003011 [Wikipedia:Lacrimal_artery] xref: EMAPA:37094 {source="MA:th"} xref: FMA:49927 xref: MA:0001988 @@ -177577,7 +177829,7 @@ def: "One of a pair of right-sided and left-sided blood vessels in the circle of subset: human_reference_atlas subset: uberon_slim subset: vertebrate_core -synonym: "arteria cerebri communicans posterior" RELATED LATIN [Wikipedia:Posterior_communicating_artery] +synonym: "arteria cerebri communicans posterior" RELATED OMO:0003011 [Wikipedia:Posterior_communicating_artery] synonym: "caudal communicating segment" EXACT [ZFA:0005001] synonym: "PCA" RELATED [] synonym: "PCS" RELATED [] @@ -177698,7 +177950,7 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "vascular element" RELATED [EMAPA:th] -synonym: "vena" RELATED LATIN [Wikipedia:Vein] +synonym: "vena" RELATED OMO:0003011 [Wikipedia:Vein] synonym: "venae" RELATED OMO:0003004 [VHOG:0001743] synonym: "venous subtree" BROAD [] synonym: "venous tree organ part" EXACT [] @@ -177754,7 +178006,7 @@ synonym: "portal vein" RELATED INCONSISTENT [] synonym: "portal vein of liver" EXACT [OBOL:automatic] synonym: "primary hepatic portal vein" RELATED [ZFA:0005090] synonym: "primary hepatic portal veins" RELATED [] -synonym: "vena portae hepatis" RELATED LATIN [Wikipedia:Hepatic_portal_vein] +synonym: "vena portae hepatis" RELATED OMO:0003011 [Wikipedia:Hepatic_portal_vein] xref: AAO:0010214 xref: FMA:50735 xref: MA:0002132 @@ -177783,16 +178035,16 @@ comment: dorsal aorta in Kardong subset: human_reference_atlas subset: pheno_slim subset: uberon_slim -synonym: "arteria coeliaca" RELATED LATIN [Wikipedia:Celiac_artery] -synonym: "arteria cœliaca" RELATED LATIN [Wikipedia:Celiac_artery] +synonym: "arteria coeliaca" RELATED OMO:0003011 [Wikipedia:Celiac_artery] +synonym: "arteria cœliaca" RELATED OMO:0003011 [Wikipedia:Celiac_artery] synonym: "celiac tree" EXACT [] synonym: "celiac trunk" RELATED [Wikipedia:Celiac_artery] synonym: "coeliac artery" EXACT [Wikipedia:Celiac_artery] synonym: "coeliac axis" RELATED [Wikipedia:Celiac_artery] synonym: "coeliac trunck" RELATED [Wikipedia:Celiac_artery] synonym: "coeliac trunk" RELATED [Wikipedia:Celiac_artery] -synonym: "truncus coeliacus" RELATED LATIN [Wikipedia:Celiac_artery] -synonym: "truncus cœliacus" RELATED LATIN [Wikipedia:Celiac_artery] +synonym: "truncus coeliacus" RELATED OMO:0003011 [Wikipedia:Celiac_artery] +synonym: "truncus cœliacus" RELATED OMO:0003011 [Wikipedia:Celiac_artery] xref: EHDAA2:0004519 xref: EMAPA:35202 xref: FMA:50737 @@ -177827,9 +178079,9 @@ synonym: "CN-V" RELATED [] synonym: "cranial nerve V" RELATED [] synonym: "fifth cranial nerve" EXACT [] synonym: "nerve V" RELATED [NeuroNames:549] -synonym: "nervus trigeminus" EXACT LATIN [Wikipedia:Trigeminal_nerve] +synonym: "nervus trigeminus" EXACT OMO:0003011 [Wikipedia:Trigeminal_nerve] synonym: "nervus trigeminus" RELATED [BTO:0001072] -synonym: "nervus trigeminus [v]" EXACT LATIN [FMA:50866, FMA:TA] +synonym: "nervus trigeminus [v]" EXACT OMO:0003011 [FMA:50866, FMA:TA] synonym: "trigeminal nerve [V]" EXACT [] synonym: "trigeminal nerve tree" EXACT [] synonym: "trigeminal V" EXACT [EHDAA2:0002084] @@ -177902,8 +178154,8 @@ synonym: "facial VII nerve" EXACT [] synonym: "nerve of face" EXACT [OBOL:automatic] synonym: "nerve VII" RELATED [NeuroNames:551] synonym: "nervus facialis" EXACT [ZFA:0000664] -synonym: "nervus facialis" RELATED LATIN [Wikipedia:Facial_nerve] -synonym: "nervus facialis [vii]" EXACT LATIN [FMA:50868, FMA:TA] +synonym: "nervus facialis" RELATED OMO:0003011 [Wikipedia:Facial_nerve] +synonym: "nervus facialis [vii]" EXACT OMO:0003011 [FMA:50868, FMA:TA] synonym: "seventh cranial nerve" EXACT [] xref: AAO:0010472 xref: BAMS:7n @@ -177963,10 +178215,10 @@ synonym: "cochlear-vestibular nerve" EXACT [] synonym: "cochleovestibular nerve" EXACT [] synonym: "cranial nerve VIII" EXACT [] synonym: "eighth cranial nerve" EXACT [] -synonym: "nervus octavus" RELATED LATIN [NeuroNames:553] -synonym: "nervus statoacusticus" RELATED LATIN [NeuroNames:553] +synonym: "nervus octavus" RELATED OMO:0003011 [NeuroNames:553] +synonym: "nervus statoacusticus" RELATED OMO:0003011 [NeuroNames:553] synonym: "nervus vestibulocochlearis" RELATED [BTO:0003490] -synonym: "nervus vestibulocochlearis [viii]" EXACT LATIN [FMA:50869, FMA:TA] +synonym: "nervus vestibulocochlearis [viii]" EXACT OMO:0003011 [FMA:50869, FMA:TA] synonym: "octaval nerve" RELATED [] synonym: "stato-acoustic nerve" EXACT [] synonym: "statoacoustic nerve" RELATED [] @@ -178031,8 +178283,8 @@ synonym: "glossopharyngeal nerve [IX]" EXACT [] synonym: "glossopharyngeal nerve tree" EXACT [] synonym: "nerve IX" RELATED [NeuroNames:701] synonym: "nervus glossopharyngeus" EXACT [ZFA:0000668] -synonym: "nervus glossopharyngeus" RELATED LATIN [Wikipedia:Glossopharyngeal_nerve] -synonym: "nervus glossopharyngeus [ix]" EXACT LATIN [FMA:50870, FMA:TA] +synonym: "nervus glossopharyngeus" RELATED OMO:0003011 [Wikipedia:Glossopharyngeal_nerve] +synonym: "nervus glossopharyngeus [ix]" EXACT OMO:0003011 [FMA:50870, FMA:TA] synonym: "ninth cranial nerve" EXACT [] xref: AAO:0010474 xref: BAMS:9n @@ -178086,9 +178338,9 @@ synonym: "hypoglossal nerve/ root" RELATED [BAMS:12n] synonym: "hypoglossal XII" EXACT [EHDAA2:0000798] synonym: "hypoglossal XII nerve" EXACT [] synonym: "nerve XII" RELATED [NeuroNames:704] -synonym: "nervi hypoglossalis" RELATED LATIN [NeuroNames:704] -synonym: "nervus hypoglossus" RELATED LATIN [Wikipedia:Hypoglossal_nerve] -synonym: "nervus hypoglossus [xii]" EXACT LATIN [FMA:50871, FMA:TA] +synonym: "nervi hypoglossalis" RELATED OMO:0003011 [NeuroNames:704] +synonym: "nervus hypoglossus" RELATED OMO:0003011 [Wikipedia:Hypoglossal_nerve] +synonym: "nervus hypoglossus [xii]" EXACT OMO:0003011 [FMA:50871, FMA:TA] synonym: "twelfth cranial nerve" EXACT [] xref: AAO:0010477 xref: BAMS:12n @@ -178136,7 +178388,7 @@ namespace: uberon def: "The pulmonary artery that supplies the right lung." [UBERON:cjm] subset: human_reference_atlas subset: uberon_slim -synonym: "arteria pulmonalis dextra" RELATED LATIN [Wikipedia:Right_pulmonary_artery] +synonym: "arteria pulmonalis dextra" RELATED OMO:0003011 [Wikipedia:Right_pulmonary_artery] synonym: "right main pulmonary artery" EXACT [] synonym: "right pulmonary arterial tree" EXACT [] xref: EMAPA:37378 {source="MA:th"} @@ -178166,7 +178418,7 @@ namespace: uberon def: "The pulmonary artery that supplies the left lung." [UBERON:cjm] subset: human_reference_atlas subset: uberon_slim -synonym: "arteria pulmonalis sinistra" RELATED LATIN [Wikipedia:Left_pulmonary_artery] +synonym: "arteria pulmonalis sinistra" RELATED OMO:0003011 [Wikipedia:Left_pulmonary_artery] synonym: "left main pulmonary artery" EXACT [] synonym: "left pulmonary arterial tree" EXACT [] xref: EMAPA:37097 {source="MA:th"} @@ -178199,7 +178451,7 @@ subset: uberon_slim synonym: "anterior facial vein" RELATED INCONSISTENT [Wikipedia:Facial_vein] synonym: "face vein" EXACT [OBOL:automatic] synonym: "vein of face" EXACT [OBOL:automatic] -synonym: "vena facialis anterior" RELATED LATIN [Wikipedia:Facial_vein] +synonym: "vena facialis anterior" RELATED OMO:0003011 [Wikipedia:Facial_vein] xref: AAO:0010513 xref: EMAPA:19220 xref: FMA:50874 @@ -178223,8 +178475,8 @@ name: cerebral vein namespace: uberon def: "The cerebral veins are divisible into external and internal groups according to the outer surfaces or the inner parts of the hemispheres they drain into. The external veins are the superior cerebral veins, inferior cerebral veins, and middle cerebral vein. [WP,unvetted]." [Wikipedia:Cerebral_veins] subset: pheno_slim -synonym: "venae cerebri" RELATED LATIN [Wikipedia:Cerebral_veins] -synonym: "venae encephali" RELATED LATIN [Wikipedia:Cerebral_veins] +synonym: "venae cerebri" RELATED OMO:0003011 [Wikipedia:Cerebral_veins] +synonym: "venae encephali" RELATED OMO:0003011 [Wikipedia:Cerebral_veins] xref: EMAPA:37140 {source="MA:th"} xref: FMA:50981 xref: GAID:530 @@ -178279,8 +178531,8 @@ synonym: "fifth ganglion" EXACT [ZFA:0000295] synonym: "fused trigeminal ganglion" NARROW SENSU [NCBITaxon:32524] synonym: "ganglion of trigeminal complex" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "ganglion of trigeminal nerve" RELATED [BTO:0001231] -synonym: "ganglion semilunare" RELATED LATIN [Wikipedia:Trigeminal_ganglion] -synonym: "ganglion trigeminale" RELATED LATIN [BTO:0001231, Wikipedia:Trigeminal_ganglion] +synonym: "ganglion semilunare" RELATED OMO:0003011 [Wikipedia:Trigeminal_ganglion] +synonym: "ganglion trigeminale" RELATED OMO:0003011 [BTO:0001231, Wikipedia:Trigeminal_ganglion] synonym: "Gasser's ganglion" RELATED [BTO:0001231] synonym: "Gasserian ganglia" RELATED OMO:0003004 [Wikipedia:Trigeminal_ganglion] synonym: "Gasserian ganglion" EXACT [Wikipedia:Trigeminal_ganglion] @@ -178334,7 +178586,7 @@ subset: pheno_slim subset: uberon_slim synonym: "occipital complex" RELATED [http://palaeos.com/vertebrates/bones/braincase/occiput.html] synonym: "occipital squama" RELATED [] -synonym: "os occipitale" RELATED LATIN [Wikipedia:Occipital_bone] +synonym: "os occipitale" RELATED OMO:0003011 [Wikipedia:Occipital_bone] xref: EMAPA:25112 xref: FMA:52735 xref: GAID:227 @@ -178368,8 +178620,8 @@ subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "butterfly bone" RELATED [Wikipedia:Sphenoid_bone] -synonym: "os sphenoidale" EXACT LATIN [FMA:52736, FMA:TA] -synonym: "os sphenoidale" RELATED LATIN [Wikipedia:Sphenoid_bone] +synonym: "os sphenoidale" EXACT OMO:0003011 [FMA:52736, FMA:TA] +synonym: "os sphenoidale" RELATED OMO:0003011 [Wikipedia:Sphenoid_bone] synonym: "os sphenoidum" RELATED [Wikipedia:Sphenoid_bone] synonym: "sphenoid" EXACT [] synonym: "sphenoid complex" RELATED [] @@ -178410,7 +178662,7 @@ def: "The large, irregular bone located at the base and side of the skull; consi subset: human_reference_atlas subset: pheno_slim subset: uberon_slim -synonym: "os temporale" RELATED LATIN [Wikipedia:Temporal_bone] +synonym: "os temporale" RELATED OMO:0003011 [Wikipedia:Temporal_bone] xref: EHDAA:6035 xref: EMAPA:17682 xref: FMA:52737 @@ -178443,7 +178695,7 @@ subset: pheno_slim subset: uberon_slim synonym: "ethmoid" EXACT [FMA:52740] synonym: "ethmoidal bone" EXACT [MP:0000101] -synonym: "os ethmoidale" EXACT LATIN [FMA:52740, FMA:TA, Wikipedia:Ethmoid] +synonym: "os ethmoidale" EXACT OMO:0003011 [FMA:52740, FMA:TA, Wikipedia:Ethmoid] xref: BTO:0004140 xref: EMAPA:19018 xref: FMA:52740 @@ -178485,7 +178737,7 @@ synonym: "hyoid" RELATED [Wikipedia:Hyoid_bone] synonym: "hyoid bone" RELATED [Wikipedia:Hyoid_bone] synonym: "hyoideum" RELATED [Wikipedia:Hyoid_bone] synonym: "lingual bone" RELATED [Wikipedia:Hyoid_bone] -synonym: "os hyoideum" RELATED LATIN [Wikipedia:Hyoid_bone] +synonym: "os hyoideum" RELATED OMO:0003011 [Wikipedia:Hyoid_bone] xref: AAO:0000684 xref: EMAPA:18650 xref: FMA:52749 @@ -178715,7 +178967,7 @@ synonym: "facial ganglion" RELATED [ZFA:0001291] synonym: "facial VII ganglion" EXACT [MA:0001076] synonym: "ganglion genicularum" EXACT [FMA:53414] synonym: "ganglion geniculi" RELATED [Wikipedia:Geniculate_ganglion] -synonym: "ganglion geniculi nervi facialis" RELATED LATIN [Wikipedia:Geniculate_ganglion] +synonym: "ganglion geniculi nervi facialis" RELATED OMO:0003011 [Wikipedia:Geniculate_ganglion] synonym: "genicular ganglion" EXACT [FMA:53414, Wikipedia:Geniculate_ganglion] synonym: "geniculate" BROAD [Wikipedia:Geniculate_ganglion] synonym: "geniculate ganglion" RELATED [MA:0001076] @@ -178862,10 +179114,10 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "cavitas nasalis" RELATED [BTO:0002096] -synonym: "cavitas nasi" RELATED LATIN [BTO:0002096, Wikipedia:Nasal_cavity] +synonym: "cavitas nasi" RELATED OMO:0003011 [BTO:0002096, Wikipedia:Nasal_cavity] synonym: "cavity of nose" EXACT [] synonym: "cavity of olfactory apparatus" EXACT [http://orcid.org/0000-0002-6601-2165] -synonym: "cavum nasi" RELATED LATIN [Wikipedia:Nasal_cavity] +synonym: "cavum nasi" RELATED OMO:0003011 [Wikipedia:Nasal_cavity] synonym: "nasal canal" EXACT [ZFA:0000130] synonym: "nasal conduit space" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "nasal fossa" EXACT [Wikipedia:Nasal_cavity] @@ -179279,7 +179531,7 @@ subset: uberon_slim synonym: "epipharynx" RELATED [Wikipedia:Pharynx] synonym: "nasal part of pharynx" EXACT [] synonym: "Nasenrachenraum" RELATED [BTO:0000662] -synonym: "pars nasalis pharyngis" RELATED LATIN [Wikipedia:Nasopharynx] +synonym: "pars nasalis pharyngis" RELATED OMO:0003011 [Wikipedia:Nasopharynx] synonym: "rhinopharynx" EXACT [] xref: BTO:0000662 xref: CALOHA:TS-0663 @@ -179311,7 +179563,7 @@ id: UBERON:0001731 name: cavity of pharynx namespace: uberon def: "An anatomical space that is enclosed by a pharynx." [OBOL:automatic] -synonym: "cavitas pharyngealis" RELATED LATIN [] +synonym: "cavitas pharyngealis" RELATED OMO:0003011 [] synonym: "cavitas pharyngis" RELATED [BTO:0002097] synonym: "lumen of pharynx" EXACT [] synonym: "pharyngeal cavity" EXACT [] @@ -179338,7 +179590,7 @@ namespace: uberon def: "The circular lymphoid tissue formed by the lingual, pharyngeal, and facial tonsils." [MGI:cwg, MP:0002379] subset: pheno_slim subset: uberon_slim -synonym: "anulus lymphoideus pharyngis" EXACT LATIN [FMA:55070, FMA:TA] +synonym: "anulus lymphoideus pharyngis" EXACT OMO:0003011 [FMA:55070, FMA:TA] synonym: "oropharyngeal lymphoid tissue" EXACT [] synonym: "pharyngeal lymphatic ring" EXACT [] synonym: "pharyngeal lymphoid ring" EXACT [] @@ -179493,7 +179745,7 @@ property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/2/2f/Ke id: UBERON:0001746 name: capsule of thyroid gland namespace: uberon -synonym: "capsula fibrosa glandulae thyroideae" EXACT LATIN [FMA:55513, FMA:TA] +synonym: "capsula fibrosa glandulae thyroideae" EXACT OMO:0003011 [FMA:55513, FMA:TA] synonym: "fibrous capsule of thyroid gland" EXACT [FMA:55513] synonym: "thyroid capsule" EXACT [] synonym: "thyroid gland capsule" EXACT [MA:0002675] @@ -179579,7 +179831,7 @@ namespace: uberon def: "A network of orbital structures of the eye that secrete and drain tears from the surface of the eyeball into the nasal cavity; these parts include the lacrimal glands, lacrimal lake, lacrimal ducts, lacrimal canals, lacrimal sacs, nasolacrimal ducts, and lacrimal puncta." [MGI:anna] subset: pheno_slim subset: uberon_slim -synonym: "apparatus lacrimalis" EXACT LATIN [Wikipedia:Lacrimal_apparatus] +synonym: "apparatus lacrimalis" EXACT OMO:0003011 [Wikipedia:Lacrimal_apparatus] synonym: "lacrimal drainage system" RELATED [https://orcid.org/0000-0002-6601-2165] synonym: "lacrymal system" EXACT [MGI:anna] synonym: "nasolacrimal drainage system" RELATED [https://orcid.org/0000-0002-6601-2165] @@ -179745,7 +179997,7 @@ namespace: uberon def: "The middle ear is the air-filled cavity within the skull of vertebrates that lies between the outer ear and the inner ear. It is linked to the pharynx (and therefore to outside air) via the Eustachian tube and in mammals contains the three ear ossicles, which transmit auditory vibrations from the outer ear (via the tympanum) to the inner ear (via the oval window)[GO]." [GO:0042474, Wikipedia:Middle_ear] subset: pheno_slim subset: uberon_slim -synonym: "auris media" RELATED LATIN [BTO:0002099, Wikipedia:Middle_ear] +synonym: "auris media" RELATED OMO:0003011 [BTO:0002099, Wikipedia:Middle_ear] xref: AAO:0011065 xref: BIRNLEX:1695 xref: BTO:0002099 @@ -179847,8 +180099,8 @@ synonym: "10n" BROAD OMO:0003000 [BIRNLEX:801, NIFSTD:NeuroNames_abbrevSource] synonym: "CN-X" RELATED [] synonym: "cranial nerve X" RELATED [] synonym: "nerve X" RELATED [NeuroNames:702] -synonym: "nervus vagus" RELATED LATIN [BTO:0003472, Wikipedia:Vagus_nerve] -synonym: "nervus vagus [x]" EXACT LATIN [FMA:5731, FMA:TA] +synonym: "nervus vagus" RELATED OMO:0003011 [BTO:0003472, Wikipedia:Vagus_nerve] +synonym: "nervus vagus [x]" EXACT OMO:0003011 [FMA:5731, FMA:TA] synonym: "pneuomgastric nerve" RELATED [BTO:0003472] synonym: "tenth cranial nerve" EXACT [] synonym: "vagal nerve" RELATED [] @@ -179905,7 +180157,7 @@ synonym: "dental papilla" RELATED [MA:0001598] synonym: "dentinal papilla" RELATED [BTO:0001839] synonym: "dermal papilla" RELATED INCONSISTENT [ISBN:0073040584] synonym: "odontogenic condensation" EXACT [VSAO:0000025] -synonym: "papilla dentis" RELATED LATIN [Wikipedia:Dental_papilla] +synonym: "papilla dentis" RELATED OMO:0003011 [Wikipedia:Dental_papilla] synonym: "pharyngeal tooth mesenchyme" NARROW SENSU [ZFA:0005140] synonym: "tooth mesenchyme" RELATED [ZFA:0005140] xref: BTO:0001839 @@ -179944,7 +180196,7 @@ def: "Epithelial tube that transports milk[GO]." [GO:0060603, Wikipedia:Lactifer comment: This structure regresses in most males subset: pheno_slim subset: uberon_slim -synonym: "ductus lactiferi" RELATED LATIN [BTO:0002845, Wikipedia:Lactiferous_duct] +synonym: "ductus lactiferi" RELATED OMO:0003011 [BTO:0002845, Wikipedia:Lactiferous_duct] synonym: "galactophorous duct" RELATED [Wikipedia:Lactiferous_duct] synonym: "galactophorous tubule" RELATED [BTO:0002845] synonym: "lactiferous duct" EXACT [FMA:58006] @@ -179980,7 +180232,7 @@ synonym: "anterior chamber" EXACT [HP:0000593, MP:0010709] synonym: "anterior chamber of eye" EXACT [] synonym: "camera anterior" EXACT [] synonym: "camera anterior bulbi" RELATED [BTO:0002084] -synonym: "camera anterior bulbi oculi" RELATED LATIN [Wikipedia:Anterior_chamber_of_eyeball] +synonym: "camera anterior bulbi oculi" RELATED OMO:0003011 [Wikipedia:Anterior_chamber_of_eyeball] synonym: "camera oculi anterior" RELATED [BTO:0002084] synonym: "eye anterior chamber" EXACT [] xref: BTO:0002084 @@ -180012,7 +180264,7 @@ subset: pheno_slim subset: uberon_slim synonym: "pars iridica retinae" RELATED [Wikipedia:Uvea] synonym: "tunica vasculatis oculi" RELATED [Wikipedia:Uvea] -synonym: "tunica vasculosa bulbi" RELATED LATIN [Wikipedia:Uvea] +synonym: "tunica vasculosa bulbi" RELATED OMO:0003011 [Wikipedia:Uvea] synonym: "tunica vasculosa of eyeball" EXACT [FMA:58103] synonym: "uvea" EXACT [FMA:58103] synonym: "uveal tract" EXACT [FMA:58103] @@ -180086,7 +180338,7 @@ name: lacrimal canaliculus namespace: uberon def: "The part of the lacrimal duct that connects the lacrimal punctum to the lacrimal sac." [http://orcid.org/0000-0002-6601-2165] subset: uberon_slim -synonym: "canaliculus lacrimalis" RELATED LATIN [Wikipedia:Lacrimal_canaliculi] +synonym: "canaliculus lacrimalis" RELATED OMO:0003011 [Wikipedia:Lacrimal_canaliculi] synonym: "lacrimal duct" RELATED [https://www.bartleby.com/lit-hub/anatomy-of-the-human-body/fig-896/, ISBN:1587341026] xref: EMAPA:37624 {source="MA:th"} xref: FMA:58245 @@ -180114,13 +180366,13 @@ synonym: "anterior corneal epithelium" EXACT [] synonym: "anterior endothelium of cornea" RELATED [BTO:0000287] synonym: "cornea epithelial tissue" EXACT [OBOL:automatic] synonym: "cornea epithelium" EXACT [OBOL:automatic] -synonym: "e. anterius corneae" RELATED LATIN [Wikipedia:Corneal_epithelium] +synonym: "e. anterius corneae" RELATED OMO:0003011 [Wikipedia:Corneal_epithelium] synonym: "endothelium anterius corneae" RELATED [BTO:0000287] synonym: "endothelium camerae anterioris bulbi" RELATED [BTO:0000287] synonym: "endothelium corneale" RELATED [BTO:0000287] synonym: "epithelial tissue of cornea" EXACT [OBOL:automatic] synonym: "epithelium anterius (cornea)" EXACT [] -synonym: "epithelium anterius corneae" EXACT LATIN [FMA:58263, FMA:TA] +synonym: "epithelium anterius corneae" EXACT OMO:0003011 [FMA:58263, FMA:TA] synonym: "epithelium corneæ anterior layer" EXACT [] synonym: "epithelium of cornea" EXACT [] synonym: "epithelium posterius corneae" RELATED [BTO:0000287] @@ -180237,7 +180489,7 @@ subset: uberon_slim subset: vertebrate_core synonym: "anterior uvea" RELATED [] synonym: "ciliary bodies" RELATED OMO:0003004 [VHOG:0000102] -synonym: "corpus ciliare" RELATED LATIN [Wikipedia:Ciliary_body] +synonym: "corpus ciliare" RELATED OMO:0003011 [Wikipedia:Ciliary_body] synonym: "ocular ciliary body" EXACT [] xref: AAO:0010341 xref: BTO:0000260 @@ -180279,7 +180531,7 @@ synonym: "chorioid" RELATED [BTO:0001829] synonym: "choroid" EXACT [MA:0000263] synonym: "choroid coat" EXACT [Wikipedia:Choroid] synonym: "choroidea" EXACT [Wikipedia:Choroid] -synonym: "choroidea" RELATED LATIN [Wikipedia:Choroid] +synonym: "choroidea" RELATED OMO:0003011 [Wikipedia:Choroid] synonym: "eye choroid" EXACT [VHOG:0001568] synonym: "optic choroid" RELATED [ZFA:0005229] synonym: "posterior uvea" EXACT [Wikipedia:Uvea#Regions] @@ -180325,7 +180577,7 @@ subset: vertebrate_core synonym: "corneal stroma" EXACT [MA:0001245] synonym: "stroma of cornea" EXACT [] synonym: "substantia propria" BROAD [] -synonym: "substantia propria corneae" EXACT LATIN [FMA:58306, FMA:TA] +synonym: "substantia propria corneae" EXACT OMO:0003011 [FMA:58306, FMA:TA] xref: CALOHA:TS-1138 xref: EFO:0002514 xref: EMAPA:17602 @@ -180415,7 +180667,7 @@ synonym: "nerve of backbone" EXACT [OBOL:automatic] synonym: "nerve of spinal column" EXACT [OBOL:automatic] synonym: "nerve of spine" EXACT [OBOL:automatic] synonym: "nerve of vertebral column" EXACT [OBOL:automatic] -synonym: "nervi spinales" RELATED LATIN [Wikipedia:Spinal_nerve] +synonym: "nervi spinales" RELATED OMO:0003011 [Wikipedia:Spinal_nerve] synonym: "spinal column nerve" EXACT [OBOL:automatic] synonym: "spinal nerve tree" EXACT [] synonym: "spinal nerves" RELATED OMO:0003004 [BAMS:spin] @@ -180480,7 +180732,7 @@ subset: uberon_slim subset: vertebrate_core synonym: "epithelium, retinal pigment" RELATED [BTO:0001177] synonym: "outer pigmented layer of retina" EXACT [] -synonym: "p. pigmentosa retinae" RELATED LATIN [Wikipedia:Retinal_pigment_epithelium] +synonym: "p. pigmentosa retinae" RELATED OMO:0003011 [Wikipedia:Retinal_pigment_epithelium] synonym: "pigment epithelium of retina" EXACT [] synonym: "pigmented epithelium" RELATED [] synonym: "pigmented retina" RELATED [] @@ -180491,9 +180743,9 @@ synonym: "retinal pigment epithelium" EXACT [MP:0005201, Wikipedia:Retinal_pigme synonym: "retinal pigment layer" RELATED [VHOG:0000536] synonym: "retinal pigmented epithelium" EXACT [ZFA:0000144] synonym: "RPE" RELATED [] -synonym: "stratum pigmentosa retinae" RELATED LATIN [Wikipedia:Retinal_pigment_epithelium] +synonym: "stratum pigmentosa retinae" RELATED OMO:0003011 [Wikipedia:Retinal_pigment_epithelium] synonym: "stratum pigmentosum (retina)" EXACT [] -synonym: "stratum pigmentosum retinae" EXACT LATIN [FMA:58627, FMA:TA] +synonym: "stratum pigmentosum retinae" EXACT OMO:0003011 [FMA:58627, FMA:TA] xref: AAO:0011096 xref: BTO:0001177 xref: CALOHA:TS-0869 @@ -180539,7 +180791,7 @@ subset: uberon_slim subset: vertebrate_core synonym: "cranial nerves" RELATED [] synonym: "cranial neural tree organ" EXACT [] -synonym: "nervus cranialis" RELATED LATIN [Wikipedia:Cranial_nerve] +synonym: "nervus cranialis" RELATED OMO:0003011 [Wikipedia:Cranial_nerve] xref: AAO:0000108 xref: BAMS:cran xref: BIRNLEX:1623 @@ -180629,7 +180881,7 @@ synonym: "retina photoreceptor layer" EXACT [] synonym: "retinal photoreceptor layer" EXACT [ZFA:0000143] synonym: "retinal photoreceptor layers" RELATED OMO:0003004 [ZFA:0000143] synonym: "stratum segmentorum externorum et internorum (retina)" EXACT [] -synonym: "stratum segmentorum externorum et internorum retinae" EXACT LATIN [FMA:58680, FMA:TA] +synonym: "stratum segmentorum externorum et internorum retinae" EXACT OMO:0003011 [FMA:58680, FMA:TA] xref: EMAPA:35686 xref: FMA:58680 xref: MA:0001308 @@ -180666,7 +180918,7 @@ synonym: "outer limiting membranes" RELATED OMO:0003004 [ZFA:0001331] synonym: "retina external limiting lamina" EXACT [] synonym: "retina outer limiting membrane" EXACT [MP:0010236] synonym: "stratum limitans externum (retina)" EXACT [] -synonym: "stratum limitans externum retinae" EXACT LATIN [FMA:58683, FMA:TA] +synonym: "stratum limitans externum retinae" EXACT OMO:0003011 [FMA:58683, FMA:TA] xref: EMAPA:36518 xref: FMA:58683 xref: MA:0001309 @@ -180698,7 +180950,7 @@ synonym: "retina, outer nuclear layer" RELATED [BAMS:Ronl] synonym: "retinal outer nuclear layer" EXACT [] synonym: "retinal outer nuclear layers" RELATED OMO:0003004 [ZFA:0001464] synonym: "stratum nucleare externum (retina)" EXACT [] -synonym: "stratum nucleare externum retinae" EXACT LATIN [FMA:58684, FMA:TA] +synonym: "stratum nucleare externum retinae" EXACT OMO:0003011 [FMA:58684, FMA:TA] xref: BAMS:Ronl xref: BTO:0005600 xref: EMAPA:19157 @@ -180735,7 +180987,7 @@ synonym: "retina, outer plexiform layer" RELATED [BAMS:Ropl] synonym: "retinal outer plexiform layer" EXACT [] synonym: "retinal outer plexiform layers" RELATED OMO:0003004 [ZFA:0001330] synonym: "stratum plexiforme externum" EXACT [] -synonym: "stratum plexiforme externum retinae" EXACT LATIN [FMA:58685, FMA:TA] +synonym: "stratum plexiforme externum retinae" EXACT OMO:0003011 [FMA:58685, FMA:TA] xref: BAMS:Ropl xref: BTO:0003174 xref: EMAPA:35744 @@ -180775,7 +181027,7 @@ synonym: "retina inner nuclear layer" EXACT [] synonym: "retina, inner nuclear layer" RELATED [BAMS:Rinl] synonym: "retinal inner nuclear layer" EXACT [] synonym: "stratum nucleare internum" EXACT [] -synonym: "stratum nucleare internum retinae" EXACT LATIN [FMA:58686, FMA:TA] +synonym: "stratum nucleare internum retinae" EXACT OMO:0003011 [FMA:58686, FMA:TA] xref: BAMS:Rinl xref: BTO:0003176 xref: EMAPA:19155 @@ -180821,7 +181073,7 @@ synonym: "retinal ganglion cell layer" EXACT [] synonym: "retinal ganglion layer" EXACT [MP:0008510] synonym: "RGC layer" EXACT [] synonym: "stratum ganglionicum (retina)" EXACT [FMA:58687] -synonym: "stratum ganglionicum retinae" RELATED LATIN [Wikipedia:Ganglion_cell_layer] +synonym: "stratum ganglionicum retinae" RELATED OMO:0003011 [Wikipedia:Ganglion_cell_layer] xref: BAMS:Rgcl xref: BTO:0003398 xref: CALOHA:TS-0867 @@ -180865,8 +181117,8 @@ synonym: "optic fiber layer" RELATED [VHOG:0001169] synonym: "optic fiber layers" RELATED OMO:0003004 [TAO:0002212] synonym: "retina nerve fiber layer" EXACT [] synonym: "stratum neurofibrarum (retina)" EXACT [] -synonym: "stratum neurofibrarum retinae" EXACT LATIN [FMA:58688, FMA:TA] -synonym: "stratum neurofibrum retinae" RELATED LATIN [Wikipedia:Nerve_fiber_layer] +synonym: "stratum neurofibrarum retinae" EXACT OMO:0003011 [FMA:58688, FMA:TA] +synonym: "stratum neurofibrum retinae" RELATED OMO:0003011 [Wikipedia:Nerve_fiber_layer] synonym: "stratum opticum of retina" EXACT [] xref: DMBA:15652 xref: EMAPA:18591 @@ -180901,7 +181153,7 @@ synonym: "internal limiting lamina of retina" EXACT [] synonym: "internal limiting membrane of retina" EXACT [] synonym: "retina inner limiting membrane" EXACT [MP:0010235] synonym: "retina internal limiting lamina" EXACT [] -synonym: "stratum limitans internum retinae" EXACT LATIN [FMA:58689, FMA:TA] +synonym: "stratum limitans internum retinae" EXACT OMO:0003011 [FMA:58689, FMA:TA] xref: EMAPA:36519 xref: FMA:58689 xref: MA:0001313 @@ -180936,7 +181188,7 @@ synonym: "retinal inner plexiform layer" EXACT [] synonym: "retinal internal plexiform layer" RELATED [NLXANAT:1005032] synonym: "stratum plexifome internum" RELATED [BTO:0003175] synonym: "stratum plexiforme internum" EXACT [FMA:58704] -synonym: "stratum plexiforme internum retinae" RELATED LATIN [Wikipedia:Inner_plexiform_layer] +synonym: "stratum plexiforme internum retinae" RELATED OMO:0003011 [Wikipedia:Inner_plexiform_layer] xref: BAMS:Ripl xref: BTO:0003175 xref: EMAPA:35741 @@ -180979,7 +181231,7 @@ subset: uberon_slim subset: vertebrate_core synonym: "aqueous humor" EXACT [] synonym: "aqueous humour" EXACT [EHDAA2:0000139] -synonym: "humor aquosus" EXACT LATIN [FMA:58819, FMA:TA] +synonym: "humor aquosus" EXACT OMO:0003011 [FMA:58819, FMA:TA] xref: EHDAA2:0000139 xref: EHDAA:10196 xref: EMAPA:18232 @@ -181012,7 +181264,7 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "humor vitreous" EXACT [] -synonym: "humor vitreus" EXACT LATIN [FMA:58822, FMA:TA] +synonym: "humor vitreus" EXACT OMO:0003011 [FMA:58822, FMA:TA] synonym: "humoral fluid" RELATED [BTO:0001451] synonym: "ocular fluid" RELATED [BTO:0001451] synonym: "portion of vitreous humor" BROAD [FMA:67388] @@ -181027,6 +181279,7 @@ xref: ENVO:02000032 xref: EV:0100344 xref: FMA:58822 xref: MA:0001286 +xref: MESH:D014822 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} xref: NCIT:C13323 xref: UMLS:C0229096 {source="ncithesaurus:Vitreous_Humor"} xref: VHOG:0000795 @@ -181068,7 +181321,7 @@ namespace: uberon def: "The chamber in the eyeball enclosing the vitreous humor, bounded anteriorly by the lens and ciliary body and posteriorly by the posterior wall of the eyeball[BTO,modified]." [BTO:0002087] subset: uberon_slim synonym: "camera postrema" EXACT [FMA:58848] -synonym: "camera postrema bulbi oculi" EXACT LATIN [FMA:58848, FMA:TA] +synonym: "camera postrema bulbi oculi" EXACT OMO:0003011 [FMA:58848, FMA:TA] synonym: "camera vitrea" EXACT [FMA:58848] synonym: "camera vitrea bulbi" EXACT [FMA:58848] synonym: "postremal chamber" EXACT [FMA:58848] @@ -181094,7 +181347,7 @@ namespace: uberon def: "The clusters of neurons in the somatic peripheral nervous system which contain the cell bodies of sensory nerve axons, interneurons and non-neuronal supporting cells." [MP:0000960] subset: human_reference_atlas subset: pheno_slim -synonym: "ganglion sensorium" EXACT LATIN [] +synonym: "ganglion sensorium" EXACT OMO:0003011 [] xref: AEO:0001000 xref: BTO:0005630 xref: EMAPA:36596 @@ -181122,7 +181375,7 @@ synonym: "anterior segment of eye" EXACT [] synonym: "anterior segment of the eye" EXACT [] synonym: "eye anterior segment" EXACT [] synonym: "segmentum anterius (bulbus oculi)" EXACT [] -synonym: "segmentum anterius bulbi oculi" RELATED LATIN [Wikipedia:Anterior_segment_of_eyeball] +synonym: "segmentum anterius bulbi oculi" RELATED OMO:0003011 [Wikipedia:Anterior_segment_of_eyeball] xref: EMAPA:36594 xref: FMA:58865 xref: MA:0002484 @@ -181153,7 +181406,7 @@ synonym: "posterior segment eye" EXACT [ZFA:0005567] synonym: "posterior segment of eye" EXACT [] synonym: "posterior segment of the eye" EXACT [] synonym: "segmentum posterius (bulbus oculi)" EXACT [] -synonym: "segmentum posterius bulbi oculi" RELATED LATIN [Wikipedia:Posterior_segment_of_eyeball] +synonym: "segmentum posterius bulbi oculi" RELATED OMO:0003011 [Wikipedia:Posterior_segment_of_eyeball] xref: EMAPA:36595 xref: FMA:58868 xref: MA:0002485 @@ -181178,7 +181431,7 @@ subset: pheno_slim subset: vertebrate_core synonym: "epithelial tissue of eye lens" EXACT [OBOL:automatic] synonym: "epithelial tissue of lens" EXACT [OBOL:automatic] -synonym: "epithelium lentis" EXACT LATIN [FMA:58871, FMA:TA] +synonym: "epithelium lentis" EXACT OMO:0003011 [FMA:58871, FMA:TA] synonym: "epithelium of eye lens" EXACT [OBOL:automatic] synonym: "eye lens epithelial tissue" EXACT [OBOL:automatic] synonym: "eye lens epithelium" EXACT [OBOL:automatic] @@ -181211,7 +181464,7 @@ def: "The elastic, clear, membrane-like structure, that is outer most layer of t subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "capsula lentis" EXACT LATIN [] +synonym: "capsula lentis" EXACT OMO:0003011 [] synonym: "lens capsule" EXACT [] xref: EHDAA2:0000977 xref: EMAPA:18237 @@ -181247,7 +181500,7 @@ def: "Ganglion that has dendrites that form a junction between autonomic nerves subset: human_reference_atlas subset: uberon_slim synonym: "autonomic nervous system ganglion" EXACT [OBOL:automatic] -synonym: "ganglion autonomicum" RELATED LATIN [Wikipedia:Autonomic_ganglion] +synonym: "ganglion autonomicum" RELATED OMO:0003011 [Wikipedia:Autonomic_ganglion] synonym: "ganglion of autonomic nervous system" EXACT [OBOL:automatic] synonym: "ganglion of visceral nervous system" EXACT [OBOL:automatic] synonym: "visceral nervous system ganglion" EXACT [OBOL:automatic] @@ -181279,7 +181532,7 @@ subset: uberon_slim synonym: "ganglion of sympathetic nervous system" EXACT [OBOL:automatic] synonym: "ganglion of sympathetic part of autonomic division of nervous system" EXACT [OBOL:automatic] synonym: "ganglion sympatheticum" EXACT [] -synonym: "ganglion sympathicum" RELATED LATIN [BTO:0001333, Wikipedia:Sympathetic_ganglion] +synonym: "ganglion sympathicum" RELATED OMO:0003011 [BTO:0001333, Wikipedia:Sympathetic_ganglion] synonym: "sympathetic nervous system ganglion" EXACT [OBOL:automatic] synonym: "sympathetic part of autonomic division of nervous system ganglion" EXACT [OBOL:automatic] xref: AAO:0010773 @@ -181289,7 +181542,7 @@ xref: EHDAA2:0001969 xref: EMAPA:17157 xref: FMA:5890 xref: MA:0000226 -xref: MESH:D005728 +xref: MESH:D005728 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: NCIT:C12467 xref: SCTID:362485003 xref: UMLS:C0017071 {source="ncithesaurus:Sympathetic_Ganglion"} @@ -181313,10 +181566,10 @@ subset: human_reference_atlas subset: uberon_slim subset: vertebrate_core synonym: "ganglia of sympathetic trunk" RELATED [Wikipedia:Paravertebral_ganglia] -synonym: "ganglia trunci sympathici" RELATED LATIN [Wikipedia:Paravertebral_ganglia] +synonym: "ganglia trunci sympathici" RELATED OMO:0003011 [Wikipedia:Paravertebral_ganglia] synonym: "ganglion of sympathetic trunk" EXACT [] -synonym: "ganglion trunci sympathetici" EXACT LATIN [] -synonym: "ganglion trunci sympathici" EXACT LATIN [FMA:5891, FMA:TA] +synonym: "ganglion trunci sympathetici" EXACT OMO:0003011 [] +synonym: "ganglion trunci sympathici" EXACT OMO:0003011 [FMA:5891, FMA:TA] synonym: "paravertebral ganglia" RELATED OMO:0003004 [FMA:80128] synonym: "paravertebral ganglion" RELATED [Wikipedia:Paravertebral_ganglia] synonym: "sympathetic chain ganglia" RELATED OMO:0003004 [Wikipedia:Paravertebral_ganglia] @@ -181346,13 +181599,13 @@ def: "Ganglion containing neurons that receive innervation from parasympathetic subset: human_reference_atlas subset: pheno_slim subset: uberon_slim -synonym: "ganglion parasympathicum" RELATED LATIN [BTO:0001256, Wikipedia:Parasympathetic_ganglion] +synonym: "ganglion parasympathicum" RELATED OMO:0003011 [BTO:0001256, Wikipedia:Parasympathetic_ganglion] xref: BTO:0001256 xref: EHDAA2:0001400 xref: EMAPA:32813 xref: FMA:5894 xref: MA:0002469 -xref: MESH:D005726 +xref: MESH:D005726 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: NCIT:C52557 xref: NLXANAT:100303 xref: SCTID:279284004 @@ -181372,7 +181625,6 @@ property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/f/f7/Gr id: UBERON:0001809 name: enteric ganglion namespace: uberon -def: "." [Wikipedia:Enteric_ganglia] subset: pheno_slim synonym: "intramural ganglion" EXACT [FMA:5896] xref: EMAPA:35312 @@ -181424,7 +181676,7 @@ subset: pheno_slim subset: uberon_slim synonym: "conjunctivae" EXACT OMO:0003004 [XAO:0000182] synonym: "conjunctivas" EXACT OMO:0003004 [XAO:0000182] -synonym: "tunica conjunctiva" EXACT LATIN [FMA:TA] +synonym: "tunica conjunctiva" EXACT OMO:0003011 [FMA:TA] synonym: "wall of conjunctival sac" EXACT [FMA:59011] xref: AAO:0010343 xref: BTO:0003415 @@ -181457,7 +181709,7 @@ id: UBERON:0001813 name: spinal nerve plexus namespace: uberon def: "An intermingling of fiber fascicles from adjacent spinal nerves to form a network." [http://www.medilexicon.com/medicaldictionary.php?t=70024] -synonym: "plexus nervorum spinalium" EXACT LATIN [FMA:5903, FMA:TA] +synonym: "plexus nervorum spinalium" EXACT OMO:0003011 [FMA:5903, FMA:TA] synonym: "plexus of spinal nerves" EXACT [FMA:5903] synonym: "somatic nerve plexus" EXACT [FMA:5903] synonym: "spinal nerve plexus" EXACT [FMA:5903] @@ -181483,7 +181735,7 @@ def: "An arrangement of nerve fibers, running from the spine where it proceeds t subset: human_reference_atlas subset: uberon_slim synonym: "brachial plexus" EXACT [MA:0001180] -synonym: "plexus brachialis" RELATED LATIN [Wikipedia:Brachial_plexus] +synonym: "plexus brachialis" RELATED OMO:0003011 [Wikipedia:Brachial_plexus] xref: EHDAA2:0000180 xref: EHDAA:3782 xref: EMAPA:16988 @@ -181513,8 +181765,8 @@ namespace: uberon def: "An arrangement of nerve fibers, running from the spine that travels to the pelvic appendage where it innervates skin and muscle." [UBERON:cjm] subset: uberon_slim synonym: "lumbosacral plexus" EXACT [] -synonym: "plexus lumbosacralis" EXACT LATIN [FMA:5907, FMA:TA] -synonym: "plexus lumbosacralis" RELATED LATIN [Wikipedia:Lumbosacral_plexus] +synonym: "plexus lumbosacralis" EXACT OMO:0003011 [FMA:5907, FMA:TA] +synonym: "plexus lumbosacralis" RELATED OMO:0003011 [Wikipedia:Lumbosacral_plexus] xref: BAMS:lsp xref: EHDAA2:0001040 xref: EHDAA:4673 @@ -181539,9 +181791,9 @@ name: autonomic nerve plexus namespace: uberon def: "A nerve plexus that is part of an autonomic nervous system [Automatically generated definition]." [OBOL:automatic] synonym: "autonomic plexus" EXACT [] -synonym: "plexus autonomicus" EXACT LATIN [FMA:5910, FMA:TA] -synonym: "plexus nervosus visceralis" EXACT LATIN [FMA:5910, FMA:TA] -synonym: "plexus visceralis" EXACT LATIN [FMA:5910, FMA:TA] +synonym: "plexus autonomicus" EXACT OMO:0003011 [FMA:5910, FMA:TA] +synonym: "plexus nervosus visceralis" EXACT OMO:0003011 [FMA:5910, FMA:TA] +synonym: "plexus visceralis" EXACT OMO:0003011 [FMA:5910, FMA:TA] synonym: "visceral nerve plexus" EXACT [] synonym: "visceral plexus" EXACT [] xref: EMAPA:18224 @@ -181562,7 +181814,7 @@ subset: efo_slim subset: organ_slim subset: pheno_slim subset: uberon_slim -synonym: "glandula lacrimalis" EXACT LATIN [Wikipedia:Lacrimal_gland] +synonym: "glandula lacrimalis" EXACT OMO:0003011 [Wikipedia:Lacrimal_gland] synonym: "glandula praeorbitalis" RELATED SENSU [NCBITaxon:91561, Wikipedia:Preorbital_gland] synonym: "lacrimal-preorbital gland" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "preorbital gland" RELATED SENSU [NCBITaxon:91561, Wikipedia:Preorbital_gland] @@ -181643,7 +181895,7 @@ subset: human_reference_atlas subset: organ_slim subset: pheno_slim subset: uberon_slim -synonym: "glandula sebacea" RELATED LATIN [Wikipedia:Sebaceous_gland] +synonym: "glandula sebacea" RELATED OMO:0003011 [Wikipedia:Sebaceous_gland] synonym: "glandula sebaceae" RELATED [BTO:0001980] synonym: "sebaceous follicle" RELATED [BTO:0001980] xref: BTO:0001980 @@ -181684,7 +181936,7 @@ xref: CALOHA:TS-0655 xref: EMAPA:37681 {source="MA:th"} xref: FMA:59502 xref: MA:0001883 -xref: MESH:D055171 +xref: MESH:D055171 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: NCIT:C49593 xref: SCTID:278941001 xref: UMLS:C0225415 {source="ncithesaurus:Nasal_Cartilage"} @@ -181712,7 +181964,7 @@ synonym: "larynx organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of organ of larynx" EXACT [OBOL:automatic] synonym: "mucous membrane of larynx" EXACT [] synonym: "organ mucosa of larynx" EXACT [OBOL:automatic] -synonym: "tunica mucosa laryngis" EXACT LATIN [FMA:59662, FMA:TA] +synonym: "tunica mucosa laryngis" EXACT OMO:0003011 [FMA:59662, FMA:TA] xref: EMAPA:18334 xref: FMA:59662 xref: GAID:301 @@ -181736,7 +181988,7 @@ synonym: "mucosa of nose" EXACT [FMA:59684] synonym: "mucous membrane of nose" EXACT [FMA:59684] synonym: "nasal mucosa" RELATED [] synonym: "tunica mucosa nasalis" EXACT [] -synonym: "tunica mucosa nasi" EXACT LATIN [FMA:59684, FMA:TA] +synonym: "tunica mucosa nasi" EXACT OMO:0003011 [FMA:59684, FMA:TA] xref: BTO:0000912 xref: CALOHA:TS-0657 xref: EMAPA:36026 @@ -181828,7 +182080,7 @@ def: "One of the two fleshy folds which surround the opening of the mouth." [htt subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "labia oris" RELATED LATIN [Wikipedia:Lip] +synonym: "labia oris" RELATED OMO:0003011 [Wikipedia:Lip] synonym: "lips" RELATED [] xref: BTO:0001647 xref: CALOHA:TS-0558 @@ -181864,7 +182116,7 @@ def: "Lip that covers the upper portion of the mouth.[TAO]." [TAO:0001970, Wikip subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "labium superius oris" RELATED LATIN [Wikipedia:Upper_lip] +synonym: "labium superius oris" RELATED OMO:0003011 [Wikipedia:Upper_lip] synonym: "upper jaw lip" EXACT [https://orcid.org/0000-0002-6601-2165] xref: EMAPA:17925 xref: FMA:59817 @@ -181892,7 +182144,7 @@ def: "Lip that covers the lower portion of the mouth.[TAO]." [TAO:0002060, Wikip subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "labium inferius oris" RELATED LATIN [Wikipedia:Lower_lip] +synonym: "labium inferius oris" RELATED OMO:0003011 [Wikipedia:Lower_lip] synonym: "lower jaw lip" EXACT [https://orcid.org/0000-0002-6601-2165] xref: EHDAA2:0001020 xref: EMAPA:17909 @@ -181918,9 +182170,9 @@ name: saliva namespace: uberon def: "A fluid produced in the oral cavity by salivary glands, typically used in predigestion, but also in other functions." [GO:0046541, Wikipedia:Saliva] subset: uberon_slim -synonym: "sailva normalis" RELATED LATIN [Wikipedia:Saliva] -synonym: "saliva atomaris" RELATED LATIN [Wikipedia:Saliva] -synonym: "saliva molecularis" RELATED LATIN [Wikipedia:Saliva] +synonym: "sailva normalis" RELATED OMO:0003011 [Wikipedia:Saliva] +synonym: "saliva atomaris" RELATED OMO:0003011 [Wikipedia:Saliva] +synonym: "saliva molecularis" RELATED OMO:0003011 [Wikipedia:Saliva] synonym: "salivary gland secretion" EXACT [FMA:59862] xref: BTO:0001202 xref: CALOHA:TS-0891 @@ -181977,7 +182229,7 @@ def: "A system of fluid passages in the inner ear, including both the cochlea, w comment: Ideally we would place a spatially disjoint from relationship to membranous labyrinth, but there are many parts in common. this should be resolved. subset: pheno_slim subset: uberon_slim -synonym: "labyrinthus osseus" RELATED LATIN [Wikipedia:Bony_labyrinth] +synonym: "labyrinthus osseus" RELATED OMO:0003011 [Wikipedia:Bony_labyrinth] synonym: "osseous labyrinth" EXACT [] synonym: "osseus labyrinth" RELATED [] xref: AAO:0011078 @@ -182007,7 +182259,7 @@ def: "One of three half-circular, interconnected tubes located inside each ear[W subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "canalis semicircularis" RELATED LATIN [Wikipedia:Semicircular_canal] +synonym: "canalis semicircularis" RELATED OMO:0003011 [Wikipedia:Semicircular_canal] synonym: "ductus semicirculares" RELATED OMO:0003004 [BTO:0003383, FMA:71880, FMA:TA] synonym: "scc" RELATED [TAO:0000431] synonym: "semicircular canals" EXACT OMO:0003004 [TAO:0000431] @@ -182097,7 +182349,7 @@ def: "Transudate contained in the osseous labyrinth outside the membranous labyr subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "liquor cotunnii" RELATED LATIN [Wikipedia:Perilymph] +synonym: "liquor cotunnii" RELATED OMO:0003011 [Wikipedia:Perilymph] synonym: "perilympha" RELATED [Wikipedia:Perilymph] xref: EMAPA:36549 xref: FMA:60908 @@ -182187,7 +182439,7 @@ def: "Organ with organ cavity which consists of the vestibular labyrinth and the subset: organ_slim subset: pheno_slim subset: uberon_slim -synonym: "labyrinthus membranaceus" EXACT LATIN [Wikipedia:Membranous_labyrinth] +synonym: "labyrinthus membranaceus" EXACT OMO:0003011 [Wikipedia:Membranous_labyrinth] xref: AAO:0011060 xref: EHDAA2:0000899 xref: EHDAA:4698 @@ -182301,7 +182553,7 @@ subset: vertebrate_core synonym: "membranous labyrinth saccule" EXACT [] synonym: "saccule" EXACT [] synonym: "sacculus" EXACT [ZFA:0000428] -synonym: "sacculus" RELATED LATIN [Wikipedia:Saccule] +synonym: "sacculus" RELATED OMO:0003011 [Wikipedia:Saccule] synonym: "sacculus (labyrinthus vestibularis)" EXACT [] xref: AAO:0000550 xref: BTO:0001805 @@ -182334,7 +182586,7 @@ subset: uberon_slim synonym: "cochlea duct" EXACT [BIRNLEX:2562] synonym: "cochlear aqueduct" RELATED [] synonym: "cochlear duct" EXACT [] -synonym: "ductus cochlearis" RELATED LATIN [BTO:0001692, Wikipedia:Cochlear_duct] +synonym: "ductus cochlearis" RELATED OMO:0003011 [BTO:0001692, Wikipedia:Cochlear_duct] synonym: "membranous cochlea" RELATED [BTO:0001692] synonym: "Reissner's canal" EXACT [FMA:61119] synonym: "Reissners canal" EXACT [BIRNLEX:2562] @@ -182374,7 +182626,7 @@ synonym: "membranous semicircular canal" RELATED [MA:0000251] xref: EMAPA:32830 xref: FMA:61122 xref: MA:0000251 -xref: MESH:D054776 +xref: MESH:D054776 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: NCIT:C33528 xref: SCTID:279833009 xref: UMLS:C1323109 {source="ncithesaurus:Semicircular_Duct"} @@ -182403,7 +182655,7 @@ xref: EMAPA:17286 xref: EMAPA:17815 xref: FMA:61255 xref: MA:0000245 -xref: MESH:D014722 +xref: MESH:D014722 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: NCIT:C33871 xref: SCTID:181188003 xref: UMLS:C0042606 {source="ncithesaurus:Vestibular_Labyrinth"} @@ -182494,10 +182746,10 @@ subset: uberon_slim synonym: "cerebrum" RELATED [https://github.com/obophenotype/uberon/issues/1208, MA:0000133, VHOG:0001639] synonym: "hemisphere" RELATED [VHOG:0001639] synonym: "hemispheric regions" RELATED [BAMS:HEM] -synonym: "hemispherium cerebri" RELATED LATIN [Wikipedia:Cerebral_hemisphere] +synonym: "hemispherium cerebri" RELATED OMO:0003011 [Wikipedia:Cerebral_hemisphere] synonym: "medial amygdalar nucleus" RELATED [NeuroNames:241] -synonym: "nucleus amygdaloideus medialis" RELATED LATIN [NeuroNames:241] -synonym: "nucleus medialis amygdalae" RELATED LATIN [NeuroNames:241] +synonym: "nucleus amygdaloideus medialis" RELATED OMO:0003011 [NeuroNames:241] +synonym: "nucleus medialis amygdalae" RELATED OMO:0003011 [NeuroNames:241] xref: AAO:0010480 xref: BAMS:HEM xref: BIRNLEX:1042 @@ -182547,6 +182799,7 @@ xref: EMAPA:35357 xref: FMA:242199 xref: GAID:674 xref: MA:0000905 +xref: MESH:D005625 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} xref: NLXANAT:20090601 xref: Wikipedia:Frontal_lobe is_a: UBERON:0016529 ! cortex of cerebral lobe @@ -182567,7 +182820,7 @@ subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim -synonym: "lobus temporalis" EXACT LATIN [Wikipedia:Temporal_lobe] +synonym: "lobus temporalis" EXACT OMO:0003011 [Wikipedia:Temporal_lobe] synonym: "temporal cortex" NARROW [] xref: BAMS:Temporal_lobe xref: BAMS:TL @@ -182603,9 +182856,9 @@ subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim -synonym: "lobus parietalis" RELATED LATIN [Wikipedia:Parietal_lobe] +synonym: "lobus parietalis" RELATED OMO:0003011 [Wikipedia:Parietal_lobe] synonym: "parietal region" BROAD [] -synonym: "regio parietalis" EXACT LATIN [FMA:61826, FMA:TA] +synonym: "regio parietalis" EXACT OMO:0003011 [FMA:61826, FMA:TA] xref: BAMS:Parietal_lobe xref: BIRNLEX:1148 xref: BTO:0001001 @@ -182642,7 +182895,7 @@ subset: uberon_slim synonym: "Ammon horn fields" RELATED [BAMS:CA] synonym: "caudatum" RELATED [BTO:0000211] synonym: "caudatus" EXACT [] -synonym: "nucleus caudatus" RELATED LATIN [BTO:0000211, Wikipedia:Caudate_nucleus] +synonym: "nucleus caudatus" RELATED OMO:0003011 [BTO:0000211, Wikipedia:Caudate_nucleus] xref: BAMS:CA xref: BAMS:Cd xref: BIRNLEX:1373 @@ -182731,8 +182984,8 @@ synonym: "amygdaloid nuclear group" RELATED [BTO:0001042] synonym: "amygdaloid nuclear groups" EXACT [] synonym: "amygdaloid nucleus" RELATED [FMA:61841] synonym: "archistriatum" EXACT [] -synonym: "corpus amygdalae" RELATED LATIN [NeuroNames:237] -synonym: "corpus amygdaloideum" RELATED LATIN [BTO:0001042, Wikipedia:Amygdala] +synonym: "corpus amygdalae" RELATED OMO:0003011 [NeuroNames:237] +synonym: "corpus amygdaloideum" RELATED OMO:0003011 [BTO:0001042, Wikipedia:Amygdala] synonym: "nucleus amygdalae" RELATED [BTO:0001042] xref: BAMS:Amg xref: BAMS:AMY @@ -182782,8 +183035,8 @@ def: "One of the seven small groups of granule cells in the polymorph layer of t subset: pheno_slim subset: uberon_slim synonym: "Calleja island" EXACT [] -synonym: "insula callejae" RELATED LATIN [Wikipedia:Islands_of_Calleja] -synonym: "insulae olfactoriae" RELATED LATIN [Wikipedia:Islands_of_Calleja] +synonym: "insula callejae" RELATED OMO:0003011 [Wikipedia:Islands_of_Calleja] +synonym: "insulae olfactoriae" RELATED OMO:0003011 [Wikipedia:Islands_of_Calleja] synonym: "islands of Calleja" EXACT [] synonym: "islands of Calleja (olfactory tubercle)" RELATED [NeuroNames:276] xref: BAMS:ICj @@ -182823,7 +183076,7 @@ subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "accumbens nucleus" EXACT [FMA:61889] -synonym: "colliculus nuclei caudati" RELATED LATIN [NeuroNames:277] +synonym: "colliculus nuclei caudati" RELATED OMO:0003011 [NeuroNames:277] synonym: "colliculus of caudate nucleus" EXACT [FMA:61889] synonym: "nucleus accumbens septi" EXACT [FMA:61889, Wikipedia:Nucleus_accumbens] xref: BAMS:ACB @@ -182868,7 +183121,7 @@ namespace: uberon def: "Region in the ventral telencephalon, prominent in rodents, but present in all mammals, consisting of a laminated cortical part and the cap/hilus region. It is traditionally viewed as part of the olfactory cortex but recognized by some as having a striatal character. According to many authors, the structure of the OT transitions from cortical like to striatal like along the lateral medial axis. (Maryann Martone)." [NLXANAT:1005037] subset: pheno_slim subset: uberon_slim -synonym: "tuberculum olfactorium" EXACT LATIN [] +synonym: "tuberculum olfactorium" EXACT OMO:0003011 [] xref: BAMS:DLT xref: BAMS:OLT xref: BAMS:OT @@ -182905,7 +183158,7 @@ subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "diaphragmatic nerve" RELATED [BTO:0001063] -synonym: "nervus phrenicus" RELATED LATIN [BTO:0001063, Wikipedia:Phrenic_nerve] +synonym: "nervus phrenicus" RELATED OMO:0003011 [BTO:0001063, Wikipedia:Phrenic_nerve] synonym: "phrenic" RELATED [BTO:0001063] xref: BAMS:phn xref: BTO:0001063 @@ -182943,7 +183196,7 @@ synonym: "dentate area" RELATED [DHBA:10295] synonym: "dentate area (dentate gyrus)" EXACT [DHBA:10295] synonym: "dentate gyrus" EXACT [] synonym: "fascia dentata" NARROW [] -synonym: "gyrus dentatus" RELATED LATIN [BTO:0002496, Wikipedia:Dentate_gyrus] +synonym: "gyrus dentatus" RELATED OMO:0003011 [BTO:0002496, Wikipedia:Dentate_gyrus] synonym: "hippocampal dentate gyrus" RELATED [BTO:0002496] xref: BAMS:DG xref: BIRNLEX:1178 @@ -182986,8 +183239,8 @@ subset: vertebrate_core synonym: "chorioid plexus" EXACT [FMA:61934] synonym: "choroid plexus of cerebral hemisphere" RELATED [FMA:61934] synonym: "CP" BROAD OMO:0003000 [PMID:23375746] -synonym: "plexus choroideus" EXACT LATIN [FMA:61934, FMA:TA] -synonym: "plexus choroideus" RELATED LATIN [Wikipedia:Choroid_plexus] +synonym: "plexus choroideus" EXACT OMO:0003011 [FMA:61934, FMA:TA] +synonym: "plexus choroideus" RELATED OMO:0003011 [Wikipedia:Choroid_plexus] synonym: "ventricular choroid plexus" RELATED [] xref: BAMS:CHP xref: BAMS:chp @@ -183036,9 +183289,9 @@ synonym: "lateral olfactory tract, body" RELATED [NeuroNames:284] synonym: "lateral olfactory tract. body" RELATED [BAMS:lot] synonym: "LOT" RELATED OMO:0003000 [] synonym: "olfactory tract" RELATED [NeuroNames:284] -synonym: "stria olfactoria lateralis" RELATED LATIN [NeuroNames:284, Wikipedia:Lateral_olfactory_stria] -synonym: "tractus olfactorius lateralis" EXACT LATIN [ZFA:0000229] -synonym: "tractus olfactorius lateralis" RELATED LATIN [NeuroNames:284] +synonym: "stria olfactoria lateralis" RELATED OMO:0003011 [NeuroNames:284, Wikipedia:Lateral_olfactory_stria] +synonym: "tractus olfactorius lateralis" EXACT OMO:0003011 [ZFA:0000229] +synonym: "tractus olfactorius lateralis" RELATED OMO:0003011 [NeuroNames:284] xref: BAMS:LDTR xref: BAMS:lo xref: BAMS:lot @@ -183140,7 +183393,7 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "MB" BROAD OMO:0003000 [BIRNLEX:1667, NIFSTD:NeuroNames_abbrevSource] -synonym: "mesencephalon" RELATED LATIN [Wikipedia:Midbrain] +synonym: "mesencephalon" RELATED OMO:0003011 [Wikipedia:Midbrain] xref: AAO:0010149 xref: BAMS:MES xref: BIRNLEX:1667 @@ -183301,7 +183554,7 @@ subset: vertebrate_core synonym: "between brain" EXACT [] synonym: "betweenbrain" RELATED [BTO:0000342] synonym: "DiE" BROAD OMO:0003000 [BIRNLEX:1503, NIFSTD:NeuroNames_abbrevSource] -synonym: "diencephalon" RELATED LATIN [Wikipedia:Diencephalon] +synonym: "diencephalon" RELATED OMO:0003011 [Wikipedia:Diencephalon] synonym: "interbrain" EXACT [Swanson:2004] synonym: "mature diencephalon" EXACT [FMA:62001] synonym: "thalamencephalon" EXACT [MGI:anna] @@ -183409,9 +183662,9 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "bulb" BROAD [] -synonym: "bulbus" EXACT LATIN [FMA:62004, FMA:TA] +synonym: "bulbus" EXACT OMO:0003011 [FMA:62004, FMA:TA] synonym: "medulla" BROAD [ABA:MY] -synonym: "medulla oblonzata" RELATED LATIN [Wikipedia:Medulla_oblongata] +synonym: "medulla oblonzata" RELATED OMO:0003011 [Wikipedia:Medulla_oblongata] synonym: "metepencephalon" RELATED [FMA:62004] xref: AAO:0010486 xref: BAMS:Md @@ -183467,10 +183720,10 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "Th" BROAD OMO:0003000 [BIRNLEX:954, NIFSTD:NeuroNames_abbrevSource, PMID:23375746] -synonym: "thalamencephalon" RELATED LATIN [NeuroNames:300] +synonym: "thalamencephalon" RELATED OMO:0003011 [NeuroNames:300] synonym: "thalami" RELATED OMO:0003004 [VHOG:0000657] synonym: "thalamus" BROAD [FMA:62007, MA:0000179] -synonym: "thalamus opticus" RELATED LATIN [NeuroNames:300] +synonym: "thalamus opticus" RELATED OMO:0003011 [NeuroNames:300] synonym: "wider thalamus" EXACT [PMCID:PMC3345571] xref: AAO:0010483 xref: BAMS:TH @@ -183523,7 +183776,7 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "Hy" BROAD OMO:0003000 [BIRNLEX:734, NIFSTD:NeuroNames_abbrevSource] -synonym: "hypothalamus" RELATED LATIN [Wikipedia:Hypothalamus] +synonym: "hypothalamus" RELATED OMO:0003011 [Wikipedia:Hypothalamus] synonym: "preoptico-hypothalamic area" EXACT [] synonym: "preoptico-hypothalamic region" EXACT [] xref: AAO:0010484 @@ -183586,7 +183839,7 @@ subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "epithalamus" RELATED LATIN [Wikipedia:Epithalamus] +synonym: "epithalamus" RELATED OMO:0003011 [Wikipedia:Epithalamus] synonym: "ETh" BROAD OMO:0003000 [BIRNLEX:1710, NIFSTD:NeuroNames_abbrevSource] xref: AAO:0010482 xref: BAMS:EPI @@ -183716,7 +183969,7 @@ synonym: "corpus pineale" EXACT [] synonym: "epiphysis" RELATED INCONSISTENT [ZFA:0000019] synonym: "epiphysis cerebri" RELATED [Wikipedia:Epiphysis_cerebri] synonym: "frontal organ" RELATED [VHOG:0000051] -synonym: "glandula pinealis" EXACT LATIN [FMA:62033, FMA:TA] +synonym: "glandula pinealis" EXACT OMO:0003011 [FMA:62033, FMA:TA] synonym: "Pi" BROAD OMO:0003000 [BIRNLEX:1184, NIFSTD:NeuroNames_abbrevSource] synonym: "pineal" RELATED [VHOG:0000051] synonym: "pineal gland" EXACT [FMA:62033] @@ -183788,8 +184041,8 @@ subset: uberon_slim subset: vertebrate_core synonym: "optic lemniscus" EXACT [] synonym: "optic tracts" RELATED OMO:0003004 [ZFA:0000252] -synonym: "tractus optici" RELATED LATIN [NeuroNames:460] -synonym: "tractus opticus" RELATED LATIN [Wikipedia:Optic_tract] +synonym: "tractus optici" RELATED OMO:0003011 [NeuroNames:460] +synonym: "tractus opticus" RELATED OMO:0003011 [Wikipedia:Optic_tract] synonym: "visual pathway" RELATED [GAID:735] xref: BAMS:opt xref: BIRNLEX:1684 @@ -183838,8 +184091,8 @@ subset: pheno_slim subset: uberon_slim synonym: "Brustdruese" RELATED [BTO:0000817] synonym: "dug" RELATED [Wikipedia:Mammary_gland] -synonym: "glandula mammaria" EXACT LATIN [FMA:57983, FMA:TA] -synonym: "glandula mammaria" RELATED LATIN [Wikipedia:Mammary_gland] +synonym: "glandula mammaria" EXACT OMO:0003011 [FMA:57983, FMA:TA] +synonym: "glandula mammaria" RELATED OMO:0003011 [Wikipedia:Mammary_gland] synonym: "lactiferous gland" EXACT [FMA:62088] synonym: "lobe of breast" NARROW [] synonym: "lobe of mammary gland" RELATED [FMA:62088] @@ -184056,13 +184309,13 @@ subset: uberon_slim synonym: "corpus geniculatum externum" RELATED [BTO:0004367] synonym: "corpus geniculatum laterale" RELATED [BTO:0004367] synonym: "corpus geniculatum laterales" EXACT [BIRNLEX:1662] -synonym: "corpus geniculatus lateralis" RELATED LATIN [NeuroNames:352] +synonym: "corpus geniculatus lateralis" RELATED OMO:0003011 [NeuroNames:352] synonym: "external geniculate body" RELATED [Wikipedia:Lateral_geniculate_nucleus] synonym: "lateral geniculate complex" EXACT [] synonym: "lateral geniculate nucleus" EXACT [] synonym: "LGB" RELATED OMO:0003000 [BTO:0004367] synonym: "LGN" BROAD OMO:0003000 [BIRNLEX:1662, NIFSTD:NeuroNames_abbrevSource] -synonym: "nucleus corporis geniculati lateralis" RELATED LATIN [BAMS:LG, NeuroNames:352] +synonym: "nucleus corporis geniculati lateralis" RELATED OMO:0003011 [BAMS:LG, NeuroNames:352] synonym: "nucleus geniculatus lateralis" EXACT [BIRNLEX:1662] xref: BAMS:C.gl. xref: BAMS:LG @@ -184099,8 +184352,8 @@ subset: uberon_slim subset: vertebrate_core synonym: "area hypothalamica rostralis" RELATED [BTO:0001796] synonym: "area praeoptica" RELATED [] -synonym: "area preoptica" RELATED LATIN [Wikipedia:Preoptic_area] -synonym: "nuclei preoptici" RELATED LATIN [NeuroNames:377] +synonym: "area preoptica" RELATED OMO:0003011 [Wikipedia:Preoptic_area] +synonym: "nuclei preoptici" RELATED OMO:0003011 [NeuroNames:377] synonym: "POA" BROAD OMO:0003000 [BIRNLEX:1706, NIFSTD:NeuroNames_abbrevSource, PMID:23375746] synonym: "preoptic hypothalamic area" RELATED [BTO:0001796] synonym: "preoptic hypothalamic region" RELATED [BTO:0001796] @@ -184144,11 +184397,11 @@ subset: efo_slim subset: pheno_slim subset: uberon_slim synonym: "filiform nucleus" EXACT [] -synonym: "nuclei paraventriculares" RELATED LATIN [NeuroNames:387] -synonym: "nuclei paraventricularis hypothalami" RELATED LATIN [Wikipedia:Paraventricular_nucleus_of_hypothalamus] -synonym: "nucleus filiformis" RELATED LATIN [NeuroNames:387] -synonym: "nucleus hypothalami filiformis" RELATED LATIN [NeuroNames:387] -synonym: "nucleus hypothalami paraventricularis" RELATED LATIN [NeuroNames:387] +synonym: "nuclei paraventriculares" RELATED OMO:0003011 [NeuroNames:387] +synonym: "nuclei paraventricularis hypothalami" RELATED OMO:0003011 [Wikipedia:Paraventricular_nucleus_of_hypothalamus] +synonym: "nucleus filiformis" RELATED OMO:0003011 [NeuroNames:387] +synonym: "nucleus hypothalami filiformis" RELATED OMO:0003011 [NeuroNames:387] +synonym: "nucleus hypothalami paraventricularis" RELATED OMO:0003011 [NeuroNames:387] synonym: "nucleus paraventricularis hypothalami" RELATED [BTO:0002476] synonym: "Pa" BROAD OMO:0003000 [BIRNLEX:1407, NIFSTD:NeuroNames_abbrevSource] synonym: "paraventricular hypothalamic nucleus" EXACT [] @@ -184200,11 +184453,11 @@ synonym: "arcuate periventricular nucleus" EXACT [] synonym: "infundibular hypothalamic nucleus" EXACT [] synonym: "infundibular nucleus" EXACT [] synonym: "infundibular periventricular nucleus" EXACT [] -synonym: "nucleus arcuatus" EXACT LATIN [FMA:62329, FMA:TA] -synonym: "nucleus arcuatus (hypothalamus)" RELATED LATIN [NeuroNames:395] -synonym: "nucleus arcuatus hypothalami" RELATED LATIN [Wikipedia:Arcuate_nucleus] +synonym: "nucleus arcuatus" EXACT OMO:0003011 [FMA:62329, FMA:TA] +synonym: "nucleus arcuatus (hypothalamus)" RELATED OMO:0003011 [NeuroNames:395] +synonym: "nucleus arcuatus hypothalami" RELATED OMO:0003011 [Wikipedia:Arcuate_nucleus] synonym: "nucleus infundibularis" RELATED [BTO:0002473] -synonym: "nucleus infundibularis hypothalami" RELATED LATIN [NeuroNames:395] +synonym: "nucleus infundibularis hypothalami" RELATED OMO:0003011 [NeuroNames:395] synonym: "nucleus semilunaris" RELATED [BTO:0002473] xref: BAMS:Arc xref: BAMS:ArcH @@ -184248,8 +184501,8 @@ subset: vertebrate_core synonym: "mesencephalic tegmentum" RELATED [VHOG:0001367] synonym: "MTg" BROAD OMO:0003000 [BIRNLEX:1200, NIFSTD:NeuroNames_abbrevSource] synonym: "tegmentum" BROAD [ISBN:0471888893] -synonym: "tegmentum mesencephali" EXACT LATIN [Wikipedia:Midbrain_tegmentum] -synonym: "tegmentum mesencephalicum" RELATED LATIN [NeuroNames:491] +synonym: "tegmentum mesencephali" EXACT OMO:0003011 [Wikipedia:Midbrain_tegmentum] +synonym: "tegmentum mesencephalicum" RELATED OMO:0003011 [NeuroNames:491] synonym: "tegmentum of midbrain" EXACT [] xref: BAMS:MTg xref: BIRNLEX:1200 @@ -184262,6 +184515,7 @@ xref: FMA:62393 xref: HBA:9002 xref: MA:0000212 xref: MAT:0000452 +xref: MESH:D013681 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} xref: neuronames:491 {source="BIRNLEX:1200"} xref: SCTID:362392007 xref: TAO:0000160 @@ -184333,7 +184587,7 @@ synonym: "neocortex (isocortex)" EXACT [DHBA:10160] synonym: "neopallial cortex" EXACT [] synonym: "neopallium" EXACT [] synonym: "nonolfactory cortex" RELATED [BTO:0000920] -synonym: "nucleus hypoglossalis" RELATED LATIN [NeuroNames:757] +synonym: "nucleus hypoglossalis" RELATED OMO:0003011 [NeuroNames:757] xref: BAMS:ISO xref: BAMS:Iso-cortex xref: BAMS:NCX @@ -184414,7 +184668,7 @@ synonym: "cornu ammonis" RELATED [GO:0021541] synonym: "hippocampus" RELATED [MA:0000191] synonym: "hippocampus major" EXACT [] synonym: "hippocampus proper" EXACT [BIRNLEX:721] -synonym: "hippocampus proprius" EXACT LATIN [FMA:62493, FMA:TA] +synonym: "hippocampus proprius" EXACT OMO:0003011 [FMA:62493, FMA:TA] xref: BAMS:CA xref: BIRNLEX:721 xref: BM:Tel-CAM @@ -184523,7 +184777,7 @@ synonym: "bronchus submucosa" EXACT [] synonym: "submucosa of bronchi" EXACT [OBOL:automatic] synonym: "submucosa of bronchial trunk" EXACT [OBOL:automatic] synonym: "submucous layer of bronchi" RELATED [BTO:0002108] -synonym: "tela submucosa bronchi" EXACT LATIN [FMA:62653, FMA:TA] +synonym: "tela submucosa bronchi" EXACT OMO:0003011 [FMA:62653, FMA:TA] xref: BTO:0002108 xref: EMAPA:37449 {source="MA:th"} xref: FMA:62653 @@ -184571,8 +184825,8 @@ def: "The parenchymatous tissue of the spleen that surrounds splenic blood vesse subset: human_reference_atlas subset: pheno_slim subset: uberon_slim -synonym: "noduli lymphoidei splenici" RELATED LATIN [Wikipedia:White_pulp] -synonym: "pulpa alba" EXACT LATIN [FMA:62805, FMA:TA] +synonym: "noduli lymphoidei splenici" RELATED OMO:0003011 [Wikipedia:White_pulp] +synonym: "pulpa alba" EXACT OMO:0003011 [FMA:62805, FMA:TA] synonym: "spleen white pulp" EXACT [] synonym: "splenic white pulp" EXACT [] synonym: "white pulp" EXACT [] @@ -184794,7 +185048,6 @@ property_value: UBPROP:0000009 "protects the organism from enteric infections by id: UBERON:0001971 name: gastric juice namespace: uberon -def: "." [Wikipedia:Gastric_juice] subset: pheno_slim subset: uberon_slim synonym: "stomach secretion" EXACT [] @@ -184826,9 +185079,9 @@ synonym: "submucosa of esophagus" EXACT [] synonym: "submucosa of gullet" EXACT [OBOL:automatic] synonym: "submucosa of oesophagus" EXACT [OBOL:automatic] synonym: "submucous layer of esophagus" RELATED [BTO:0002109] -synonym: "tela submucosa (oesophagus)" EXACT LATIN [FMA:62997, FMA:TA] -synonym: "tela submucosa esophagi" EXACT LATIN [BTO:0002109] -synonym: "tela submucosa oesophageae" EXACT LATIN [FMA:62997, FMA:TA] +synonym: "tela submucosa (oesophagus)" EXACT OMO:0003011 [FMA:62997, FMA:TA] +synonym: "tela submucosa esophagi" EXACT OMO:0003011 [BTO:0002109] +synonym: "tela submucosa oesophageae" EXACT OMO:0003011 [FMA:62997, FMA:TA] synonym: "tela submucosa oesophagi" RELATED [BTO:0002109] synonym: "tela submucosa of esophagus" EXACT [] xref: BTO:0002109 @@ -184892,7 +185145,7 @@ synonym: "serous coat of oesophagus" EXACT [] synonym: "serous membrane of esophagus" EXACT [OBOL:automatic] synonym: "serous membrane of gullet" EXACT [OBOL:automatic] synonym: "serous membrane of oesophagus" EXACT [OBOL:automatic] -synonym: "tunica serosa oesophageae" EXACT LATIN [FMA:63057, FMA:TA] +synonym: "tunica serosa oesophageae" EXACT OMO:0003011 [FMA:63057, FMA:TA] xref: EMAPA:35322 xref: FMA:63057 xref: MA:0001571 @@ -184969,7 +185222,7 @@ subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "venula" RELATED LATIN [Wikipedia:Venule] +synonym: "venula" RELATED OMO:0003011 [Wikipedia:Venule] xref: BTO:0002626 xref: EMAPA:35917 xref: FMA:63130 @@ -184998,7 +185251,7 @@ def: "The smallest division of the artery located between the muscular arteries subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "arteriola" RELATED LATIN [Wikipedia:Arteriole] +synonym: "arteriola" RELATED OMO:0003011 [Wikipedia:Arteriole] xref: AAO:0010253 xref: BTO:0001997 xref: EMAPA:35146 @@ -185035,7 +185288,7 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "region of vascular tree organ" EXACT [FMA:50722] -synonym: "vas sanguineum" RELATED LATIN [Wikipedia:Blood_vessel] +synonym: "vas sanguineum" RELATED OMO:0003011 [Wikipedia:Blood_vessel] synonym: "vascular element" BROAD [EMAPA:35993] synonym: "vascular tree organ region" EXACT [FMA:50722] xref: AAO:0011004 @@ -185194,7 +185447,7 @@ subset: uberon_slim subset: vertebrate_core synonym: "cornea endothelium" EXACT [OBOL:automatic] synonym: "endothelium of cornea" EXACT [OBOL:automatic] -synonym: "epithelium posterius corneae" RELATED LATIN [Wikipedia:Corneal_endothelium] +synonym: "epithelium posterius corneae" RELATED OMO:0003011 [Wikipedia:Corneal_endothelium] xref: CALOHA:TS-0172 xref: EMAPA:35935 xref: FMA:63882 @@ -185321,7 +185574,7 @@ synonym: "portion of fecal matter" EXACT [] synonym: "portion of feces" EXACT [] synonym: "portion of guano" NARROW [] synonym: "portion of scat" NARROW [] -synonym: "portionem cacas" EXACT LATIN [] +synonym: "portionem cacas" EXACT OMO:0003011 [] synonym: "scat" NARROW [] synonym: "spoor" RELATED [] synonym: "spraint" NARROW [Wikipedia:Spraint] @@ -185360,10 +185613,10 @@ synonym: "papillary dermis" EXACT [] synonym: "papillary layer" EXACT [MP:0009545] synonym: "papillary layer of dermis" EXACT [FMA:64776] synonym: "stratum papillare" EXACT [MP:0009545] -synonym: "stratum papillare" RELATED LATIN [Wikipedia:Papillary_dermis] -synonym: "stratum papillare (dermis)" EXACT LATIN [FMA:64776, FMA:TA] +synonym: "stratum papillare" RELATED OMO:0003011 [Wikipedia:Papillary_dermis] +synonym: "stratum papillare (dermis)" EXACT OMO:0003011 [FMA:64776, FMA:TA] synonym: "stratum papillare corii" EXACT [MP:0009545] -synonym: "stratum papillare dermis" EXACT LATIN [FMA:64776, FMA:TA] +synonym: "stratum papillare dermis" EXACT OMO:0003011 [FMA:64776, FMA:TA] synonym: "superficial dermis" EXACT [MA:0000802, MP:0009545] xref: EMAPA:35282 xref: FMA:64776 @@ -185395,8 +185648,8 @@ synonym: "dermis reticular layer" EXACT [] synonym: "dermis stratum reticulare" EXACT [] synonym: "reticular dermis" EXACT [] synonym: "stratum reticulare" EXACT [Wikipedia:Reticular_dermis] -synonym: "stratum reticulare" RELATED LATIN [Wikipedia:Reticular_dermis] -synonym: "stratum reticulare dermis" EXACT LATIN [FMA:64778, FMA:TA] +synonym: "stratum reticulare" RELATED OMO:0003011 [Wikipedia:Reticular_dermis] +synonym: "stratum reticulare dermis" EXACT OMO:0003011 [FMA:64778, FMA:TA] xref: EMAPA:35283 xref: FMA:64778 xref: MA:0000801 @@ -185450,7 +185703,7 @@ synonym: "stratified cartilage tissue" EXACT [http://orcid.org/0000-0002-6601-21 xref: FMA:64784 xref: galen:Fibrocartilage xref: MA:0000108 -xref: MESH:D051445 +xref: MESH:D051445 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: NCIT:C32599 xref: SCTID:91685003 xref: UMLS:C0684077 {source="ncithesaurus:Fibrocartilage"} @@ -185625,7 +185878,7 @@ def: "Peripheral portion of the lymph node, underneath the capsule[WP]." [Wikipe subset: human_reference_atlas subset: pheno_slim subset: uberon_slim -synonym: "cortex nodi lymphoidei" RELATED LATIN [Wikipedia:Cortex_of_lymph_node] +synonym: "cortex nodi lymphoidei" RELATED OMO:0003011 [Wikipedia:Cortex_of_lymph_node] synonym: "lymph node cortex" EXACT [] xref: EMAPA:35525 xref: FMA:66253 @@ -185650,7 +185903,7 @@ subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "lymph node medulla" EXACT [] -synonym: "medulla nodi lymphoidei" RELATED LATIN [Wikipedia:Medulla_of_lymph_node] +synonym: "medulla nodi lymphoidei" RELATED OMO:0003011 [Wikipedia:Medulla_of_lymph_node] xref: EMAPA:35529 xref: FMA:66254 xref: MA:0000745 @@ -185675,7 +185928,7 @@ synonym: "autonomic plexus of heart" EXACT [OBOL:automatic] synonym: "cardiac plexus" EXACT [] synonym: "heart autonomic nerve plexus" EXACT [OBOL:automatic] synonym: "heart autonomic plexus" EXACT [OBOL:automatic] -synonym: "plexus cardiacus" EXACT LATIN [Wikipedia:Cardiac_plexus] +synonym: "plexus cardiacus" EXACT OMO:0003011 [Wikipedia:Cardiac_plexus] xref: EMAPA:37460 {source="MA:th"} xref: FMA:6628 xref: MA:0001138 @@ -185697,7 +185950,7 @@ namespace: uberon def: "The thoracodorsal artery is a branch of the subscapular artery. It travels inferiorly with the thoracodorsal nerve and supplies the latissimus dorsi. [WP,unvetted]." [Wikipedia:Thoracodorsal_artery] subset: human_reference_atlas subset: uberon_slim -synonym: "arteria thoracodorsalis" RELATED LATIN [Wikipedia:Thoracodorsal_artery] +synonym: "arteria thoracodorsalis" RELATED OMO:0003011 [Wikipedia:Thoracodorsal_artery] xref: EMAPA:37129 {source="MA:th"} xref: FMA:66320 xref: MA:0002065 @@ -185721,11 +185974,11 @@ subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim -synonym: "arteria pulmonalis" RELATED LATIN [Wikipedia:Pulmonary_artery] +synonym: "arteria pulmonalis" RELATED OMO:0003011 [Wikipedia:Pulmonary_artery] synonym: "pulmonary arterial subtree" RELATED [FMA:66326] synonym: "pulmonary arterial tree" EXACT [FMA:66326] synonym: "pulmonary arterial tree organ part" EXACT [FMA:66326] -synonym: "truncus pulmonalis" RELATED LATIN [Wikipedia:Pulmonary_artery] +synonym: "truncus pulmonalis" RELATED OMO:0003011 [Wikipedia:Pulmonary_artery] xref: AAO:0010221 xref: BTO:0000778 xref: CALOHA:TS-0839 @@ -185773,7 +186026,7 @@ def: "The tough fibrous layer surrounding the kidney which is covered in a thick subset: human_reference_atlas subset: pheno_slim subset: uberon_slim -synonym: "capsula fibrosa renis" EXACT LATIN [FMA:66610, FMA:TA] +synonym: "capsula fibrosa renis" EXACT OMO:0003011 [FMA:66610, FMA:TA] synonym: "capsule of kidney" EXACT [] synonym: "fibrous capsule of kidney" EXACT [FMA:66610] synonym: "renal capsule" EXACT [GO:0072127] @@ -185809,7 +186062,7 @@ subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "pulmonary venous tree organ part" EXACT [] -synonym: "venae pulmonales" RELATED LATIN [Wikipedia:Pulmonary_vein] +synonym: "venae pulmonales" RELATED OMO:0003011 [Wikipedia:Pulmonary_vein] xref: AAO:0010521 xref: BTO:0001799 xref: CALOHA:TS-0840 @@ -185881,10 +186134,10 @@ namespace: uberon def: "Soft tissue that lines the non-cartilaginous surfaces within joints with cavities (synovial joints)." [Wikipedia:Synovial_membrane] subset: efo_slim subset: uberon_slim -synonym: "membrana synovialis (capsula articularis)" EXACT LATIN [FMA:9865, FMA:TA] -synonym: "membrana synovialis capsulae articularis" EXACT LATIN [Wikipedia:Synovial_membrane] -synonym: "stratum synoviale" EXACT LATIN [FMA:66762, FMA:TA] -synonym: "stratum synoviale (capsula articularis)" EXACT LATIN [FMA:9865, FMA:TA] +synonym: "membrana synovialis (capsula articularis)" EXACT OMO:0003011 [FMA:9865, FMA:TA] +synonym: "membrana synovialis capsulae articularis" EXACT OMO:0003011 [Wikipedia:Synovial_membrane] +synonym: "stratum synoviale" EXACT OMO:0003011 [FMA:66762, FMA:TA] +synonym: "stratum synoviale (capsula articularis)" EXACT OMO:0003011 [FMA:9865, FMA:TA] synonym: "synovial layer" BROAD [FMA:66762] synonym: "synovial layer of articular capsule of synovial joint" RELATED [FMA:9865] synonym: "synovial membrane" BROAD [AEO:0000181] @@ -185933,9 +186186,9 @@ synonym: "cervical accessory nerve" EXACT [] synonym: "CN-XI" RELATED [VHOG:0000699] synonym: "cranial nerve XI" EXACT [BIRNLEX:812] synonym: "eleventh cranial nerve" EXACT [BIRNLEX:812] -synonym: "nervus accessorius [XI]" EXACT LATIN [FMA:6720, FMA:TA] -synonym: "pars spinalis nervus accessorius" EXACT LATIN [FMA:6720, FMA:TA] -synonym: "radix spinalis nervus accessorius" EXACT LATIN [FMA:6720, FMA:TA] +synonym: "nervus accessorius [XI]" EXACT OMO:0003011 [FMA:6720, FMA:TA] +synonym: "pars spinalis nervus accessorius" EXACT OMO:0003011 [FMA:6720, FMA:TA] +synonym: "radix spinalis nervus accessorius" EXACT OMO:0003011 [FMA:6720, FMA:TA] synonym: "spinal accessory nerve" EXACT [FMA:6720] synonym: "spinal accessory nerve tree" EXACT [] synonym: "spinal part of accessory nerve" EXACT [] @@ -185990,9 +186243,9 @@ synonym: "gray matter of neuraxis" EXACT [FMA:67242] synonym: "grey matter" EXACT [] synonym: "grey matter of neuraxis" EXACT [] synonym: "grey substance" EXACT [] -synonym: "grisea" RELATED LATIN [] +synonym: "grisea" RELATED OMO:0003011 [] synonym: "neuronal grey matter" EXACT [AEO:0001012] -synonym: "substantia grisea" EXACT LATIN [FMA:67242, FMA:TA] +synonym: "substantia grisea" EXACT OMO:0003011 [FMA:67242, FMA:TA] xref: AEO:0001012 xref: EHDAA2:0003136 xref: EHDAA2_RETIRED:0004658 @@ -186000,7 +186253,7 @@ xref: EMAPA:37596 {source="MA:th"} xref: FMA:67242 xref: HBA:4006 xref: MA:0001112 -xref: MESH:D066128 +xref: MESH:D066128 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: NCIT:C32695 xref: neuronames:2869 xref: TAO:0002197 @@ -186038,7 +186291,7 @@ synonym: "stratum basalis of epidermis" EXACT [] synonym: "stratum germinativum" EXACT [] synonym: "stratum germinosum" BROAD [] synonym: "stratum germinosum of epidermis" EXACT [] -synonym: "stratum Malpighi" BROAD LATIN [Wikipedia:Malpighian_layer] +synonym: "stratum Malpighi" BROAD OMO:0003011 [Wikipedia:Malpighian_layer] xref: AAO:0010598 xref: BTO:0000438 xref: EMAPA:32779 @@ -186076,7 +186329,7 @@ synonym: "Malpighian layer" BROAD [Wikipedia:Malpighian_layer] synonym: "prickle cell layer" RELATED [BTO:0000435] synonym: "prickle cell layer of epidermis" EXACT [FMA:67542] synonym: "squamous cell layer of epidermis" EXACT [] -synonym: "stratum Malpighii" BROAD LATIN [Wikipedia:Malpighian] +synonym: "stratum Malpighii" BROAD OMO:0003011 [Wikipedia:Malpighian] synonym: "stratum spinosum" EXACT [] xref: BTO:0000435 xref: EMAPA:32785 @@ -186112,7 +186365,7 @@ synonym: "horny layer of epidermis" EXACT [FMA:67545] synonym: "keratinized squame layer" BROAD [] synonym: "keratinized squame layer of epidermis" EXACT [] synonym: "stratum corneum" BROAD [] -synonym: "stratum corneum epidermidis" RELATED LATIN [Wikipedia:Stratum_corneum] +synonym: "stratum corneum epidermidis" RELATED OMO:0003011 [Wikipedia:Stratum_corneum] xref: AAO:0010597 xref: BTO:0000344 xref: CALOHA:TS-0981 @@ -186228,7 +186481,7 @@ comment: Nipple being part_of mammary gland is due to a practical modelling in u subset: pheno_slim subset: uberon_slim synonym: "papilla mammae" EXACT [MP:0009723] -synonym: "papilla mammaria" RELATED LATIN [Wikipedia:Nipple] +synonym: "papilla mammaria" RELATED OMO:0003011 [Wikipedia:Nipple] synonym: "papilla of breast" EXACT [] synonym: "papillary part of breast" NARROW [] synonym: "teat" NARROW [] @@ -186356,10 +186609,10 @@ subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "corpus cerebelli" RELATED LATIN [NeuroNames:643] +synonym: "corpus cerebelli" RELATED OMO:0003011 [NeuroNames:643] synonym: "epencephalon-1" EXACT [FMA:67944] synonym: "infratentorial region" BROAD [Wikipedia:Tentorium_cerebelli] -synonym: "parencephalon" RELATED LATIN [NeuroNames:643] +synonym: "parencephalon" RELATED OMO:0003011 [NeuroNames:643] xref: AAO:0010485 xref: BAMS:CB xref: BAMS:Cb @@ -186419,11 +186672,11 @@ subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "nucleus of basis pedunculi" EXACT [] -synonym: "nucleus pigmentosus subthalamo-peduncularis" RELATED LATIN [NeuroNames:536] +synonym: "nucleus pigmentosus subthalamo-peduncularis" RELATED OMO:0003011 [NeuroNames:536] synonym: "SN" BROAD OMO:0003000 [BIRNLEX:789, NIFSTD:NeuroNames_abbrevSource] synonym: "Soemmering's substance" EXACT [] synonym: "substancia nigra" RELATED [Wikipedia:Substantia_nigra] -synonym: "substantia nigra (Soemmerringi)" RELATED LATIN [NeuroNames:536] +synonym: "substantia nigra (Soemmerringi)" RELATED OMO:0003011 [NeuroNames:536] xref: BAMS:SN xref: BIRNLEX:789 xref: BTO:0000143 @@ -186468,9 +186721,9 @@ def: "A systemic artery that supplies the lung with with oxygenated blood." [UBE comment: Although there is much variation, there are usually two bronchial arteries that run to the left lung, and one to the right lung. subset: human_reference_atlas subset: uberon_slim -synonym: "arteriae bronchiales" RELATED LATIN [Wikipedia:Bronchial_artery] +synonym: "arteriae bronchiales" RELATED OMO:0003011 [Wikipedia:Bronchial_artery] synonym: "bronchial arterial tree" EXACT [] -synonym: "rami bronchiales partis thoracicae aortae" RELATED LATIN [Wikipedia:Bronchial_artery] +synonym: "rami bronchiales partis thoracicae aortae" RELATED OMO:0003011 [Wikipedia:Bronchial_artery] xref: EMAPA:18608 xref: FMA:68109 xref: GAID:477 @@ -186531,7 +186784,7 @@ subset: efo_slim subset: organ_slim subset: pheno_slim subset: uberon_slim -synonym: "glandula thyroidea" RELATED LATIN [Wikipedia:Thyroid] +synonym: "glandula thyroidea" RELATED OMO:0003011 [Wikipedia:Thyroid] synonym: "thyroid" EXACT [] xref: AAO:0010544 xref: BTO:0001379 @@ -186578,11 +186831,11 @@ namespace: uberon def: "The pontine raphe nucleus is one of the raphe nuclei. It is located in the pontine tegmentum. [WP,unvetted]." [Wikipedia:Pontine_raphe_nucleus] subset: pheno_slim subset: uberon_slim -synonym: "nucleus raphe pontis" RELATED LATIN [NeuroNames:589] -synonym: "nucleus raphes pontis" RELATED LATIN [Wikipedia:Pontine_raphe_nucleus] -synonym: "raphe (mediana pontina)" RELATED LATIN [NeuroNames:589] +synonym: "nucleus raphe pontis" RELATED OMO:0003011 [NeuroNames:589] +synonym: "nucleus raphes pontis" RELATED OMO:0003011 [Wikipedia:Pontine_raphe_nucleus] +synonym: "raphe (mediana pontina)" RELATED OMO:0003011 [NeuroNames:589] synonym: "raphe of pons" EXACT [] -synonym: "raphe pontis" EXACT LATIN [FMA:68875, FMA:TA] +synonym: "raphe pontis" EXACT OMO:0003011 [FMA:68875, FMA:TA] synonym: "raphe pontis nucleus" RELATED [] xref: BAMS:PnR xref: BAMS:RA-PONS @@ -186618,7 +186871,7 @@ subset: major_organ subset: organ_slim subset: pheno_slim subset: uberon_slim -synonym: "pulmo" EXACT LATIN [] +synonym: "pulmo" EXACT OMO:0003011 [] xref: AAO:0000275 xref: AAO:0010567 xref: BTO:0000763 @@ -186703,7 +186956,7 @@ xref: BILA:0000034 xref: BTO:0000174 xref: CALOHA:TS-2110 xref: EFO:0000461 -xref: FBbt:00004208 +xref: FBbt:00004208 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:69067 xref: GAID:407 xref: MESH:D004628 @@ -186808,7 +187061,7 @@ namespace: uberon def: "Each renal artery gives off some small inferior suprarenal branches to the suprarenal gland, the ureter, and the surrounding cellular tissue and muscles. [WP,unvetted]." [Wikipedia:Inferior_suprarenal_artery] subset: human_reference_atlas subset: uberon_slim -synonym: "arteria suprarenalis inferior" RELATED LATIN [Wikipedia:Inferior_suprarenal_artery] +synonym: "arteria suprarenalis inferior" RELATED OMO:0003011 [Wikipedia:Inferior_suprarenal_artery] xref: EMAPA:37088 {source="MA:th"} xref: FMA:69264 xref: MA:0002056 @@ -186846,7 +187099,7 @@ name: femoral artery namespace: uberon def: "The femoral artery is a large artery in the muscles of the thigh. It is a continuation of external iliac artery where it enters the femoral triangle at the mid inguinal point behind the inguinal ligament. It leaves femoral triangle through apex beneath the sartorius muscle. It enters the popliteal fossa by passing through the 5th osseo-aponeurotic(adductor hiatus) opening of adductor magnus where it becomes the Popliteal Artery. [WP,unvetted]." [Wikipedia:Femoral_artery] subset: uberon_slim -synonym: "arteria femoralis" RELATED LATIN [Wikipedia:Femoral_artery] +synonym: "arteria femoralis" RELATED OMO:0003011 [Wikipedia:Femoral_artery] xref: AAO:0010222 xref: BTO:0001624 xref: CALOHA:TS-0321 @@ -186910,7 +187163,7 @@ xref: EHDAA:2586 xref: EMAPA:16696 xref: FMA:70302 xref: MA:0000078 -xref: MESH:D054089 +xref: MESH:D054089 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: TAO:0001317 xref: VHOG:0000932 xref: Wikipedia:Atrioventricular_cushions @@ -186936,7 +187189,7 @@ subset: uberon_slim subset: vertebrate_core synonym: "inflow tract" BROAD [ZFA:0000154] synonym: "sinus venarum" RELATED [Wikipedia:Sinus_venosus] -synonym: "sinus venosus cordis" RELATED LATIN [Wikipedia:Sinus_venosus] +synonym: "sinus venosus cordis" RELATED OMO:0003011 [Wikipedia:Sinus_venosus] synonym: "venarum" RELATED [Wikipedia:Sinus_venosus] synonym: "venarum sinus" RELATED [Wikipedia:Sinus_venosus] synonym: "venosus" RELATED [Wikipedia:Sinus_venosus] @@ -186975,7 +187228,7 @@ subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim -synonym: "vena umbilicalis" RELATED LATIN [Wikipedia:Umbilical_vein] +synonym: "vena umbilicalis" RELATED OMO:0003011 [Wikipedia:Umbilical_vein] xref: BTO:0001509 xref: CALOHA:TS-1082 xref: EFO:0001940 @@ -187009,7 +187262,7 @@ subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "corium" RELATED LATIN [BTO:0000294, Wikipedia:Dermis] +synonym: "corium" RELATED OMO:0003011 [BTO:0000294, Wikipedia:Dermis] synonym: "cutis" RELATED [BTO:0000294] synonym: "vertebrate dermis" EXACT [] xref: AAO:0000128 @@ -187091,12 +187344,13 @@ synonym: "subcutaneous tissue" RELATED [Wikipedia:Hypodermis] synonym: "subcutis" RELATED [] synonym: "subtegumental tissue" RELATED [BTO:0004525] synonym: "superficial fascia" RELATED INCONSISTENT [] -synonym: "tela subcutanea" RELATED LATIN [Wikipedia:Hypodermis] +synonym: "tela subcutanea" RELATED OMO:0003011 [Wikipedia:Hypodermis] synonym: "vertebrate hypodermis" EXACT [] xref: BTO:0001314 xref: CALOHA:TS-2366 xref: EMAPA:37505 {source="MA:th"} xref: FMA:70544 +xref: MESH:D040521 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} xref: NCIT:C33645 xref: TAO:0001136 xref: UMLS:C0278403 {source="ncithesaurus:Subcutis"} @@ -187130,7 +187384,7 @@ subset: human_reference_atlas subset: organ_slim subset: pheno_slim subset: uberon_slim -synonym: "folliculus pili" RELATED LATIN [Wikipedia:Hair_follicle] +synonym: "folliculus pili" RELATED OMO:0003011 [Wikipedia:Hair_follicle] xref: BTO:0000554 xref: CALOHA:TS-0432 xref: EFO:0002464 @@ -187253,7 +187507,7 @@ def: "A cardiac atrium that is in the right side of the heart. It receives deoxy subset: human_reference_atlas subset: pheno_slim subset: uberon_slim -synonym: "atrium dextrum" RELATED LATIN [Wikipedia:Right_atrium] +synonym: "atrium dextrum" RELATED OMO:0003011 [Wikipedia:Right_atrium] synonym: "cardiac right atrium" EXACT [] synonym: "heart right atrium" EXACT [MA:0000075] synonym: "right atrium" EXACT [VHOG:0000328] @@ -187293,7 +187547,7 @@ def: "A cardiac atrium that is in the left side of the heart. It receives oxygen subset: human_reference_atlas subset: pheno_slim subset: uberon_slim -synonym: "atrium sinistrum" EXACT LATIN [Wikipedia:Left_atrium] +synonym: "atrium sinistrum" EXACT OMO:0003011 [Wikipedia:Left_atrium] synonym: "cardiac left atrium" EXACT [] synonym: "heart left atrium" EXACT [MA:0000074] synonym: "left atrium" EXACT [VHOG:0000369] @@ -187338,7 +187592,7 @@ synonym: "cardiac right ventricle" EXACT [] synonym: "right cardiac ventricle" RELATED [EMAPA:17340] synonym: "right ventricle" EXACT [FMA:7098] synonym: "right ventricle of heart" EXACT [] -synonym: "ventriculus dexter" RELATED LATIN [Wikipedia:Right_ventricle] +synonym: "ventriculus dexter" RELATED OMO:0003011 [Wikipedia:Right_ventricle] xref: BTO:0001630 xref: CALOHA:TS-0443 xref: EHDAA2:0000196 @@ -187465,7 +187719,7 @@ synonym: "cardiac left ventricle" EXACT [] synonym: "left cardiac ventricle" EXACT [] synonym: "left ventricle" EXACT [FMA:7101] synonym: "left ventricle of heart" EXACT [] -synonym: "ventriculus sinister cordis" RELATED LATIN [Wikipedia:Left_ventricle] +synonym: "ventriculus sinister cordis" RELATED OMO:0003011 [Wikipedia:Left_ventricle] xref: BTO:0001629 xref: CALOHA:TS-0439 xref: EHDAA2:0002178 @@ -187562,6 +187816,7 @@ xref: EMAPA:37721 {source="MA:th"} xref: FMA:71221 xref: MA:0002986 xref: MAT:0000148 +xref: MESH:D013131 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} xref: MIAA:0000148 xref: TAO:0000317 xref: VHOG:0000317 @@ -187591,7 +187846,7 @@ subset: vertebrate_core synonym: "appendicular skeleton" EXACT [] synonym: "entire appendicular skeleton" EXACT [https://github.com/obophenotype/uberon/issues/59] synonym: "paired fin skeleton" NARROW SENSU [] -synonym: "skeleton appendiculare" RELATED LATIN [Wikipedia:Appendicular_skeleton] +synonym: "skeleton appendiculare" RELATED OMO:0003011 [Wikipedia:Appendicular_skeleton] xref: AAO:0000747 xref: EFO:0000951 xref: EMAPA:32729 @@ -187626,7 +187881,7 @@ namespace: uberon def: "The fibrous membrane forming the outer of the three coverings that surrounds the brain within the cranial cavity; consists of two layers including the periosteal layer and the meningeal layer." [MP:0009025] subset: pheno_slim synonym: "cranial dura mater" EXACT [FMA:71236] -synonym: "dura mater cranialis" EXACT LATIN [FMA:71236, FMA:TA] +synonym: "dura mater cranialis" EXACT OMO:0003011 [FMA:71236, FMA:TA] synonym: "dura mater encephali" EXACT [] synonym: "dura mater of brain" EXACT [] xref: EMAPA:32668 @@ -187683,7 +187938,7 @@ synonym: "heart ventricular septum" EXACT [MA:0000085] synonym: "interventricular septum of heart" RELATED [BTO:0002483] synonym: "interventriculare cordis" RELATED [BTO:0002483] synonym: "intraventricular septum" RELATED [Wikipedia:Interventricular_septum] -synonym: "s. interventriculare cordis" RELATED LATIN [Wikipedia:Interventricular_septum] +synonym: "s. interventriculare cordis" RELATED OMO:0003011 [Wikipedia:Interventricular_septum] synonym: "septum inferius" RELATED [Wikipedia:Interventricular_septum] synonym: "septum membranaceum" RELATED [Wikipedia:Interventricular_septum] synonym: "ventricle septum" RELATED [] @@ -187885,6 +188140,7 @@ xref: GAID:36 xref: galen:Extremity xref: MA:0000007 xref: MAT:0000090 +xref: MESH:D005121 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} xref: MIAA:0000090 xref: NCIT:C12429 xref: SCTID:243996003 @@ -187917,7 +188173,7 @@ synonym: "foreleg" RELATED [] synonym: "forelimb" EXACT [] synonym: "free part of upper limb" EXACT [FMA:24878] synonym: "free upper limb" EXACT [FMA:24878, UBERONREF:0000003] -synonym: "membrum superius" EXACT LATIN [FMA:7183, FMA:TA] +synonym: "membrum superius" EXACT OMO:0003011 [FMA:7183, FMA:TA] synonym: "pectoral flipper" NARROW SENSU [] synonym: "pectoral limb" EXACT [] synonym: "superior member" EXACT [] @@ -187975,8 +188231,8 @@ synonym: "hindlimb" EXACT [] synonym: "inferior member" EXACT [] synonym: "lower extremity" RELATED [] synonym: "lower limb" EXACT [] -synonym: "membrum inferius" EXACT LATIN [FMA:7184, FMA:TA] -synonym: "membrum inferius" RELATED LATIN [Wikipedia:Lower_limb] +synonym: "membrum inferius" EXACT OMO:0003011 [FMA:7184, FMA:TA] +synonym: "membrum inferius" RELATED OMO:0003011 [Wikipedia:Lower_limb] synonym: "pelvic appendage" RELATED [] xref: AAO:0000219 xref: BTO:0002345 @@ -188081,7 +188337,7 @@ subset: organ_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "lien" RELATED LATIN [Wikipedia:Spleen] +synonym: "lien" RELATED OMO:0003011 [Wikipedia:Spleen] xref: AAO:0010395 xref: BTO:0001281 xref: CALOHA:TS-0956 @@ -188134,8 +188390,8 @@ subset: organ_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "iecur" RELATED LATIN [Wikipedia:Liver] -synonym: "jecur" RELATED LATIN [Wikipedia:Liver] +synonym: "iecur" RELATED OMO:0003011 [Wikipedia:Liver] +synonym: "jecur" RELATED OMO:0003011 [Wikipedia:Liver] xref: AAO:0010111 xref: BTO:0000759 xref: CALOHA:TS-0564 @@ -188200,7 +188456,7 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "anterior intestine" RELATED [] -synonym: "intestinum tenue" RELATED LATIN [BTO:0000651, Wikipedia:Small_intestine] +synonym: "intestinum tenue" RELATED OMO:0003011 [BTO:0000651, Wikipedia:Small_intestine] synonym: "mid intestine" RELATED [] synonym: "small bowel" EXACT [] synonym: "small intestine" EXACT [] @@ -188272,8 +188528,8 @@ subset: uberon_slim subset: vertebrate_core synonym: "cholecyst" EXACT [WikipediaVersioned:Gallbladder&oldid=1092217922] synonym: "gall bladder" EXACT [] -synonym: "vesica biliaris" RELATED LATIN [Wikipedia:Gallbladder] -synonym: "vesica fellea" RELATED LATIN [Wikipedia:Gallbladder] +synonym: "vesica biliaris" RELATED OMO:0003011 [Wikipedia:Gallbladder] +synonym: "vesica fellea" RELATED OMO:0003011 [Wikipedia:Gallbladder] xref: AAO:0010114 xref: BTO:0000493 xref: CALOHA:TS-0394 @@ -188611,7 +188867,7 @@ xref: EHDAA:1017 xref: EMAPA:16579 xref: FMA:72170 xref: MAT:0000117 -xref: MESH:D060910 +xref: MESH:D060910 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: MIAA:0000117 xref: NCIT:C34280 xref: SCTID:308804007 @@ -188744,8 +189000,8 @@ name: superior olivary complex namespace: uberon def: "A collection of brainstem nuclei that functions in multiple aspects of hearing and is an important component of the ascending and descending auditory pathways of the auditory system." [ISBN:0-19-502694-2, Wikipedia:Superior_olivary_complex] subset: uberon_slim -synonym: "nucleus olivaris superior" EXACT LATIN [FMA:72247, FMA:TA] -synonym: "regio olivaris superioris" RELATED LATIN [NeuroNames:569] +synonym: "nucleus olivaris superior" EXACT OMO:0003011 [FMA:72247, FMA:TA] +synonym: "regio olivaris superioris" RELATED OMO:0003011 [NeuroNames:569] synonym: "superior olivary nuclei" EXACT [FMA:72247] synonym: "superior olivary nucleus" RELATED INCONSISTENT [FMA:72247] synonym: "superior olivary nucleus (Barr & Kiernan)" RELATED [NeuroNames:569] @@ -188759,7 +189015,7 @@ xref: FMA:72247 xref: HBA:9177 xref: MA:0001026 xref: MBA:398 -xref: MESH:D065832 +xref: MESH:D065832 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: neuronames:569 {source="BIRNLEX:1307"} xref: UMLS:C0175427 {source="BIRNLEX:1307"} xref: VHOG:0001381 @@ -188785,7 +189041,7 @@ subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "cortex cerebellaris" RELATED [BTO:0000043] -synonym: "cortex cerebelli" RELATED LATIN [NeuroNames:647] +synonym: "cortex cerebelli" RELATED OMO:0003011 [NeuroNames:647] synonym: "cortex of cerebellar hemisphere" EXACT [DMBA:CbHCx] xref: BAMS:CB xref: BAMS:CbCx @@ -188830,9 +189086,9 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "cerebral aqueduct subcommissural organ" RELATED [BAMS:SCO] -synonym: "corpus subcommissurale" RELATED LATIN [NeuroNames:483] +synonym: "corpus subcommissurale" RELATED OMO:0003011 [NeuroNames:483] synonym: "dorsal subcommissural organ" RELATED [] -synonym: "organum subcommissurale" RELATED LATIN [Wikipedia:Subcommissural_organ] +synonym: "organum subcommissurale" RELATED OMO:0003011 [Wikipedia:Subcommissural_organ] synonym: "SCO" RELATED [] xref: BAMS:SCO xref: BIRNLEX:1028 @@ -188880,8 +189136,8 @@ synonym: "locus coeruleu" EXACT [] synonym: "locus coeruleus" EXACT [] synonym: "locus coeruleus (Vicq d'Azyr)" RELATED [NeuroNames:583] synonym: "Noradrenergic cell group A6" EXACT [Noradrenergic_cell_group_A6&oldid=981960774] -synonym: "nucleus caeruleus" EXACT LATIN [FMA:72478, FMA:TA] -synonym: "nucleus loci caerulei" RELATED LATIN [NeuroNames:583] +synonym: "nucleus caeruleus" EXACT OMO:0003011 [FMA:72478, FMA:TA] +synonym: "nucleus loci caerulei" RELATED OMO:0003011 [NeuroNames:583] synonym: "nucleus of locus caeruleus" EXACT [] synonym: "nucleus pigmentosus pontis" EXACT [BIRNLEX:905] synonym: "substantia ferruginea" EXACT [BIRNLEX:905] @@ -188925,10 +189181,10 @@ name: superior salivatory nucleus namespace: uberon def: "Nucleus containing parasympathetic neurons giving rise to the parasympathetic division of the facial nerve, innervating the salivary glands (Brodal, Neurological Anatomy, 3rd ed., 1981, pg 703)." [BIRNLEX:1131] subset: uberon_slim -synonym: "nucleus salivarius superior" RELATED LATIN [NeuroNames:590] -synonym: "nucleus salivatorius cranialis" RELATED LATIN [NeuroNames:590] -synonym: "nucleus salivatorius rostralis" RELATED LATIN [NeuroNames:590] -synonym: "nucleus salivatorius superior" RELATED LATIN [NeuroNames:590] +synonym: "nucleus salivarius superior" RELATED OMO:0003011 [NeuroNames:590] +synonym: "nucleus salivatorius cranialis" RELATED OMO:0003011 [NeuroNames:590] +synonym: "nucleus salivatorius rostralis" RELATED OMO:0003011 [NeuroNames:590] +synonym: "nucleus salivatorius superior" RELATED OMO:0003011 [NeuroNames:590] synonym: "superior salivary nucleus" EXACT [GO:0021753] xref: BAMS:SSN xref: BAMS:SuS @@ -189131,7 +189387,7 @@ subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "alveolar duct" EXACT [MA:0000417] -synonym: "ductus alveolaris" EXACT LATIN [FMA:7341, FMA:TA] +synonym: "ductus alveolaris" EXACT OMO:0003011 [FMA:7341, FMA:TA] synonym: "respiratory alveolar duct" EXACT [] xref: EMAPA:32694 xref: FMA:7341 @@ -189155,7 +189411,7 @@ subset: vertebrate_core synonym: "anterior funiculus" EXACT [] synonym: "anterior funiculus of spinal cord" EXACT [] synonym: "anterior white column of spinal cord" EXACT [FMA:74003] -synonym: "funiculus anterior medullae spinalis" EXACT LATIN [FMA:74003, FMA:TA] +synonym: "funiculus anterior medullae spinalis" EXACT OMO:0003011 [FMA:74003, FMA:TA] synonym: "ventral funiculi" RELATED OMO:0003004 [ZFA:0000605] synonym: "ventral funiculus" EXACT [ZFA:0000605] synonym: "ventral funiculus of spinal cord" EXACT [] @@ -189180,7 +189436,7 @@ def: "The lobar bronchus is the major airway within the respiratory tree that st subset: human_reference_atlas subset: organ_slim subset: uberon_slim -synonym: "bronchi lobaris" EXACT LATIN [Wikipedia:Secondary_bronchus] +synonym: "bronchi lobaris" EXACT OMO:0003011 [Wikipedia:Secondary_bronchus] synonym: "lobar bronchi" RELATED OMO:0003004 [Wikipedia:Secondary_bronchus] synonym: "secondary bronchi" RELATED OMO:0003004 [Wikipedia:Secondary_bronchus] synonym: "secondary bronchus" EXACT [FMA:7406, Wikipedia:Secondary_bronchus] @@ -189252,6 +189508,7 @@ name: bronchus namespace: uberon def: "The upper conducting airways of the lung; these airways arise from the terminus of the trachea." [ISBN:0-397-51047-0, MESH:A04.411.125, MGI:cwg, MP:0002264] subset: efo_slim +subset: human_reference_atlas subset: organ_slim subset: pheno_slim subset: uberon_slim @@ -189279,6 +189536,7 @@ is_a: UBERON:0000117 ! respiratory tube relationship: located_in UBERON:0002224 ! thoracic cavity relationship: never_in_taxon NCBITaxon:8507 {source="Wikipedia"} relationship: part_of UBERON:0007196 ! tracheobronchial tree +relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/1/18/Respiratory_system_complete_numbered.svg" xsd:anyURI property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.4/3d-vh-f-lung.glb" xsd:anyURI property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.4/3d-vh-m-lung.glb" xsd:anyURI @@ -189305,7 +189563,7 @@ xref: EHDAA:8221 xref: EMAPA:32697 xref: FMA:7410 xref: MA:0000422 -xref: MESH:D055745 +xref: MESH:D055745 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: NCIT:C12684 xref: SCTID:278982001 xref: UMLS:C0006270 {source="ncithesaurus:Bronchiole"} @@ -189327,8 +189585,8 @@ def: "A bronchiole that is part of a secondary pulmonary lobule and the last con subset: human_reference_atlas subset: pheno_slim subset: uberon_slim -synonym: "bronchioli terminalis" RELATED LATIN [Wikipedia:Terminal_bronchiole] -synonym: "bronchiolus terminalis" EXACT LATIN [] +synonym: "bronchioli terminalis" RELATED OMO:0003011 [Wikipedia:Terminal_bronchiole] +synonym: "bronchiolus terminalis" EXACT OMO:0003011 [] synonym: "terminal bronchiole tube" RELATED [] xref: BTO:0003223 xref: EMAPA:36282 @@ -189353,8 +189611,8 @@ def: "A bronchiole that is the first segment of the respiratory zone." [ISBN:012 subset: human_reference_atlas subset: pheno_slim subset: uberon_slim -synonym: "bronchiolus respiratorii" EXACT LATIN [Wikipedia:Respiratory_bronchiole] -synonym: "bronchiolus respiratorius" EXACT LATIN [FMA:7412] +synonym: "bronchiolus respiratorii" EXACT OMO:0003011 [Wikipedia:Respiratory_bronchiole] +synonym: "bronchiolus respiratorius" EXACT OMO:0003011 [FMA:7412] xref: BTO:0003222 xref: EMAPA:35729 xref: FMA:7412 @@ -189384,14 +189642,15 @@ synonym: "fatty layer of subcutaneous tissue" EXACT [FMA:74315] synonym: "fatty layer of superficial fascia" RELATED [FMA:74315] synonym: "hypodermis fat layer" EXACT [MP:0011156] synonym: "panniculus adiposus" BROAD [MP:0011156] -synonym: "panniculus adiposus (tela subcutanea)" EXACT LATIN [FMA:74315, FMA:TA] -synonym: "panniculus adiposus telae subcutaneae" EXACT LATIN [FMA:74315, FMA:TA] +synonym: "panniculus adiposus (tela subcutanea)" EXACT OMO:0003011 [FMA:74315, FMA:TA] +synonym: "panniculus adiposus telae subcutaneae" EXACT OMO:0003011 [FMA:74315, FMA:TA] synonym: "subcutaneous fat" RELATED [BTO:0004042] synonym: "subcutaneous fat layer" EXACT [MP:0011156] xref: BTO:0004042 xref: EMAPA:35829 xref: FMA:74315 xref: MA:0000473 +xref: MESH:D015434 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} is_a: UBERON:0001013 ! adipose tissue intersection_of: UBERON:0001013 ! adipose tissue intersection_of: part_of UBERON:0002072 ! hypodermis @@ -189400,6 +189659,49 @@ relationship: part_of UBERON:0002072 ! hypodermis relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens property_value: UBPROP:0000001 "the superficial portion of the subcutaneous tissue which is specialized for fat storage[MP:0011156]" xsd:string {source="MP:0011156"} +[Term] +id: UBERON:0002191 +name: subiculum +namespace: uberon +def: "Part of the hippocampal formation that is bounded by the entorhinal cortex and area CA1. It is characterized on the CA1 border by an abrupt widening of the pyramidal cell layer. A molecular layer is present that is continuous with that of CA1, although the stratum radiatum is no longer present. The stratum oriens is also not present. adapted from Paxinos, G. The rat central nervous system, 2nd ed, Academic Press, San Diego, 1995, pg. 468)." [BIRNLEX:1305] +subset: pheno_slim +subset: uberon_slim +synonym: "gyrus parahippocampalis" RELATED [BTO:0003087] +synonym: "subicular cortex" EXACT [BIRNLEX:1305] +synonym: "subiculum cornu ammonis" RELATED [BTO:0003087] +synonym: "subiculum hippocampi" EXACT [FMA:74414] +xref: BAMS:S +xref: BAMS:SUB +xref: BIRNLEX:1305 +xref: BM:Tel-Cx-SB +xref: BTO:0003087 +xref: DHBA:10301 +xref: DHBA:10302 +xref: DMBA:16163 +xref: EMAPA:35832 +xref: FMA:74414 +xref: HBA:12896 +xref: MA:0000960 +xref: MBA:502 +xref: NCIT:C33648 +xref: neuronames:188 +xref: PBA:10054 +xref: PBA:128012354 +xref: SCTID:369097009 +xref: UMLS:C0152316 {source="ncithesaurus:Subiculum"} +xref: Wikipedia:Subiculum +is_a: UBERON:0002616 ! regional part of brain +relationship: capable_of_part_of GO:0007613 {source="Wikipedia"} ! memory +relationship: part_of UBERON:0002421 {source="NIFSTD"} ! hippocampal formation +property_value: depiction "https://upload.wikimedia.org/wikipedia/commons/9/99/Hippocampus.gif" xsd:anyURI +property_value: RO:0002171 UBERON:0001953 {source="ABA"} +property_value: RO:0002171 UBERON:0002728 {source="ABA"} +property_value: RO:0002171 UBERON:0004683 {source="ABA"} +property_value: UBPROP:0000007 "subicular" xsd:string +property_value: UBPROP:0000009 "The pyramidal neurons in the subiculum exhibit transitions between two modes of action potential output: bursting and single spiking. The transitions between these two modes is thought to be important for routing information out of the hippocampus. It is the site responsible for ictal activity in some cases of human epilepsy. It has also been implicated in working memory and drug addiction.[Wikipedia:Subiculum]" xsd:string +property_value: UBPROP:0000012 "In ABA SUB is part of the retrohippocampal region, along with the entorhinal area. this is in the hippocampal formation but not the hippocampal region" xsd:string {external_ontology="ABA"} +property_value: UBPROP:0000012 "in DHBA subicular cortex is divided into subiculum, prosubiculum and supracallosal subiculum" xsd:string + [Term] id: UBERON:0002193 name: hemolymphoid system @@ -189423,7 +189725,7 @@ namespace: uberon def: "Capsule surrounding lymph node composed of connective tissue with some plain muscle fibers." [Wikipedia:Lymph_node#Capsule] subset: human_reference_atlas subset: uberon_slim -synonym: "capsula nodi lymphoidei" EXACT LATIN [FMA:74604, FMA:TA] +synonym: "capsula nodi lymphoidei" EXACT OMO:0003011 [FMA:74604, FMA:TA] synonym: "lymph node capsule" EXACT [] xref: EMAPA:35524 xref: FMA:74604 @@ -189485,9 +189787,9 @@ synonym: "anterior lobe of the pituitary" RELATED [BAMS:APit] synonym: "anterior pituitary" EXACT [] synonym: "anterior pituitary gland" RELATED [BTO:0000040] synonym: "cranial lobe" RELATED [BTO:0000496] -synonym: "lobus anterior" RELATED LATIN [NeuroNames:407] -synonym: "lobus anterior (glandula pituitaria)" EXACT LATIN [FMA:74627, FMA:TA] -synonym: "lobus anterior hypophysis" EXACT LATIN [FMA:74627, FMA:TA] +synonym: "lobus anterior" RELATED OMO:0003011 [NeuroNames:407] +synonym: "lobus anterior (glandula pituitaria)" EXACT OMO:0003011 [FMA:74627, FMA:TA] +synonym: "lobus anterior hypophysis" EXACT OMO:0003011 [FMA:74627, FMA:TA] synonym: "pituitary anterior lobe" RELATED [EMAPA:17514] synonym: "pituitary gland, anterior lobe" EXACT [] synonym: "pituitary glandanterior lobe" RELATED [BAMS:AL] @@ -189543,11 +189845,11 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "infundibular process" EXACT [FMA:74628] -synonym: "lobus nervosus" RELATED LATIN [NeuroNames:401] -synonym: "lobus nervosus neurohypophysis" EXACT LATIN [FMA:74628, FMA:TA] -synonym: "lobus posterior" RELATED LATIN [NeuroNames:401] -synonym: "lobus posterior (glandula pituitaria)" EXACT LATIN [FMA:74628, FMA:TA] -synonym: "lobus posterior hypophysis" EXACT LATIN [FMA:74628, FMA:TA] +synonym: "lobus nervosus" RELATED OMO:0003011 [NeuroNames:401] +synonym: "lobus nervosus neurohypophysis" EXACT OMO:0003011 [FMA:74628, FMA:TA] +synonym: "lobus posterior" RELATED OMO:0003011 [NeuroNames:401] +synonym: "lobus posterior (glandula pituitaria)" EXACT OMO:0003011 [FMA:74628, FMA:TA] +synonym: "lobus posterior hypophysis" EXACT OMO:0003011 [FMA:74628, FMA:TA] synonym: "neural lobe" EXACT [FMA:74628] synonym: "neural lobe of pituitary" EXACT [BIRNLEX:1586] synonym: "neural lobe of pituitary gland" EXACT [FMA:74628] @@ -189614,7 +189916,7 @@ subset: vertebrate_core synonym: "dermal system" RELATED [BTO:0000634] synonym: "dermis plus epidermis plus hypodermis" EXACT [] synonym: "dermoid system" RELATED [BTO:0000634] -synonym: "integumentum commune" EXACT LATIN [FMA:74657, FMA:TA] +synonym: "integumentum commune" EXACT OMO:0003011 [FMA:74657, FMA:TA] synonym: "skin" RELATED [] synonym: "skin and subcutaneous tissue" EXACT [] synonym: "skin plus hypodermis" EXACT [] @@ -189794,12 +190096,12 @@ subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "corpora mamillaria" RELATED LATIN [NeuroNames:412] -synonym: "corpora mammillaria" RELATED LATIN [NeuroNames:412] +synonym: "corpora mamillaria" RELATED OMO:0003011 [NeuroNames:412] +synonym: "corpora mammillaria" RELATED OMO:0003011 [NeuroNames:412] synonym: "corpus mamillare" EXACT [ZFA:0000334] -synonym: "corpus mamillare" RELATED LATIN [Wikipedia:Mammillary_body] -synonym: "corpus mamillaris" RELATED LATIN [NeuroNames:412] -synonym: "corpus mammillare" RELATED LATIN [NeuroNames:412] +synonym: "corpus mamillare" RELATED OMO:0003011 [Wikipedia:Mammillary_body] +synonym: "corpus mamillaris" RELATED OMO:0003011 [NeuroNames:412] +synonym: "corpus mammillare" RELATED OMO:0003011 [NeuroNames:412] synonym: "mammillary area" RELATED [DMBA:Mam] synonym: "MMB" BROAD OMO:0003000 [BIRNLEX:865, NIFSTD:NeuroNames_abbrevSource] xref: BAMS:MB @@ -189843,7 +190145,7 @@ def: "Nonsynovial joint in which the articulating bones or cartilages are connec subset: uberon_slim subset: vertebrate_core synonym: "articulatio fibrosa" EXACT [] -synonym: "junctura fibrosa" RELATED LATIN [Wikipedia:Fibrous_joint] +synonym: "junctura fibrosa" RELATED OMO:0003011 [Wikipedia:Fibrous_joint] xref: AEO:0000178 xref: EHDAA2:0003178 xref: EMAPA:35344 @@ -189878,7 +190180,7 @@ namespace: uberon def: "A continuation of the neuron projection bundle component of a nerve inside, crossing or immediately outside the central nervous system." [http://orcid.org/0000-0002-6601-2165, https://github.com/obophenotype/uberon/issues/286] subset: uberon_slim synonym: "initial segment of nerve" EXACT [http://orcid.org/0000-0002-6601-2165] -synonym: "radix nervi" EXACT LATIN [] +synonym: "radix nervi" EXACT OMO:0003011 [] xref: FMA:5981 xref: FMA:82524 xref: NCIT:C54024 @@ -189905,8 +190207,8 @@ synonym: "macula of membranous labyrinth saccule" EXACT [OBOL:automatic] synonym: "macula of saccule" EXACT [] synonym: "macula of sacculus (labyrinthus vestibularis)" EXACT [OBOL:automatic] synonym: "macula saccule" EXACT [ZFA:0007000] -synonym: "macula sacculi" EXACT LATIN [FMA:74944, FMA:TA] -synonym: "macula sacculi" RELATED LATIN [Wikipedia:Macula_of_saccule] +synonym: "macula sacculi" EXACT OMO:0003011 [FMA:74944, FMA:TA] +synonym: "macula sacculi" RELATED OMO:0003011 [Wikipedia:Macula_of_saccule] synonym: "membranous labyrinth saccule macula" EXACT [OBOL:automatic] synonym: "saccular macula" EXACT [ZFA:0007000] synonym: "saccular macula of membranous labyrinth" EXACT [] @@ -189938,7 +190240,7 @@ def: "Nonsynovial joint in which the articulating bones or cartilages are connec subset: uberon_slim subset: vertebrate_core synonym: "articulatio cartilaginea" EXACT [] -synonym: "junctura cartilaginea" RELATED LATIN [Wikipedia:Cartilaginous_joint] +synonym: "junctura cartilaginea" RELATED OMO:0003011 [Wikipedia:Cartilaginous_joint] xref: EMAPA:36581 xref: FMA:7496 xref: MA:0000320 @@ -189964,8 +190266,8 @@ synonym: "macula of membranous labyrinth utricle" EXACT [OBOL:automatic] synonym: "macula of utricle" EXACT [] synonym: "macula of utriculus (labyrinthus vestibularis)" EXACT [OBOL:automatic] synonym: "macula utricle" EXACT [ZFA:0000030] -synonym: "macula utriculi" EXACT LATIN [FMA:74960, FMA:TA] -synonym: "macula utriculi" RELATED LATIN [Wikipedia:Macula_of_utricle] +synonym: "macula utriculi" EXACT OMO:0003011 [FMA:74960, FMA:TA] +synonym: "macula utriculi" RELATED OMO:0003011 [Wikipedia:Macula_of_utricle] synonym: "maculae utricle" RELATED OMO:0003004 [ZFA:0000030] synonym: "membranous labyrinth utricle macula" EXACT [OBOL:automatic] synonym: "utricle macula" EXACT [OBOL:automatic] @@ -189996,7 +190298,7 @@ namespace: uberon def: "Cartilaginous joint in which the articulating bones or cartilages are connected by hyaline cartilage. Examples: spheno-occipital synchondrosis, first sternocostal joint.[FMA]." [FMA:FMA, Wikipedia:Synchondrosis] subset: pheno_slim subset: uberon_slim -synonym: "cartilago epiphysialis" EXACT LATIN [FMA:7497, FMA:TA] +synonym: "cartilago epiphysialis" EXACT OMO:0003011 [FMA:7497, FMA:TA] synonym: "epiphysial cartilage" RELATED [FMA:7497] synonym: "primary cartilaginous joint" EXACT [FMA:7497] xref: EMAPA:35846 @@ -190096,7 +190398,7 @@ namespace: uberon def: "The part of the coelemic cavity lumen that is enclosed by the walls of the thorax." [UBERON:cjm, Wikipedia:Thoracic_cavity] subset: pheno_slim subset: uberon_slim -synonym: "cavitas thoracis" EXACT LATIN [Wikipedia:Thoracic_cavity] +synonym: "cavitas thoracis" EXACT OMO:0003011 [Wikipedia:Thoracic_cavity] synonym: "cavity of chest" EXACT [] synonym: "cavity of thorax" EXACT [] synonym: "chest cavity" EXACT [] @@ -190136,7 +190438,7 @@ synonym: "basilar papilla" RELATED SENSU [XAO:0003145] synonym: "cochlear spiral organ" EXACT [] synonym: "Corti's organ" RELATED [BTO:0001691] synonym: "organ of Corti" RELATED [] -synonym: "organum spirale" EXACT LATIN [Wikipedia:Organ_of_Corti] +synonym: "organum spirale" EXACT OMO:0003011 [Wikipedia:Organ_of_Corti] synonym: "papilla basilaris" RELATED SENSU [XAO:0003145] synonym: "spiral organ" EXACT [] synonym: "spiral organ of Corti" EXACT [] @@ -190195,6 +190497,7 @@ xref: SCTID:302523002 xref: TAO:0000538 xref: UMLS:C0035561 {source="ncithesaurus:Rib"} xref: VHOG:0001154 +xref: VO:0012403 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: Wikipedia:Rib xref: ZFA:0000538 is_a: UBERON:0002513 ! endochondral bone @@ -190216,7 +190519,7 @@ namespace: uberon def: "A proximal phalanx that is part of a finger [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "hand proximal phalanx" EXACT [MA:0001395] -synonym: "phalanx proximalis manus" EXACT LATIN [FMA:75816, FMA:TA] +synonym: "phalanx proximalis manus" EXACT OMO:0003011 [FMA:75816, FMA:TA] synonym: "proximal manual phalanx" EXACT [] synonym: "proximal phalanx of finger" EXACT [FMA:75816] synonym: "proximal phalanx of fore digit" EXACT [] @@ -190268,9 +190571,9 @@ subset: uberon_slim subset: vertebrate_core synonym: "cerebro-cerebellar fissure" RELATED [NeuroNames:22] synonym: "cerebrocerebellar fissure" RELATED [NeuroNames:22] -synonym: "fissura cerebro-cerebellaris" RELATED LATIN [NeuroNames:22] -synonym: "fissura cerebrocerebellaris" RELATED LATIN [NeuroNames:22] -synonym: "medulla spinalis" RELATED LATIN [BTO:0001279, Wikipedia:Spinal_cord] +synonym: "fissura cerebro-cerebellaris" RELATED OMO:0003011 [NeuroNames:22] +synonym: "fissura cerebrocerebellaris" RELATED OMO:0003011 [NeuroNames:22] +synonym: "medulla spinalis" RELATED OMO:0003011 [BTO:0001279, Wikipedia:Spinal_cord] synonym: "SpC" RELATED OMO:0003000 [] synonym: "spinal cord structure" RELATED [ZFA:0000075] synonym: "spinal medulla" RELATED [BTO:0001279] @@ -190362,7 +190665,7 @@ xref: EMAPA:18008 xref: FMA:13550 xref: FMA:76703 xref: MA:0000112 -xref: MESH:D000070614 +xref: MESH:D000070614 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: SCTID:316586000 xref: Wikipedia:Nucleus_pulposus is_a: PR:000050567 ! protein-containing material entity @@ -190391,8 +190694,8 @@ subset: pheno_slim subset: uberon_slim synonym: "Jacobson's organ" EXACT [XAO:0000272] synonym: "organ of Jacobsen" RELATED [] -synonym: "organon vomeronasale" EXACT LATIN [] -synonym: "organum vomeronasale" EXACT LATIN [Wikipedia:Vomeronasal_organ] +synonym: "organon vomeronasale" EXACT OMO:0003011 [] +synonym: "organum vomeronasale" EXACT OMO:0003011 [Wikipedia:Vomeronasal_organ] synonym: "VNO" RELATED [VHOG:0000665] xref: AAO:0000997 xref: BTO:0002608 @@ -190430,9 +190733,9 @@ namespace: uberon def: "The pronounced, dorsolaterally oriented ridge of grey matter in each lateral half of the spinal cord[MP]. the dorsal (more towards the back) grey matter of the spinal cord. It receives several types of sensory information from the body, including light touch, proprioception, and vibration. This information is sent from receptors of the skin, bones, and joints through sensory neurons whose cell bodies lie in the dorsal root ganglion[WP]. The dorsal region of the mature spinal cord contains neurons that process and relay sensory input[GO]." [GO:0021516, https://sourceforge.net/tracker/?group_id=36855&atid=440764, MP:0006282, Wikipedia:Posterior_horn_of_spinal_cord] subset: pheno_slim subset: vertebrate_core -synonym: "columna grisea posterior medullae spinalis" EXACT LATIN [FMA:256530, FMA:TA] +synonym: "columna grisea posterior medullae spinalis" EXACT OMO:0003011 [FMA:256530, FMA:TA] synonym: "cornu dorsale" EXACT [ZFA:0000649] -synonym: "cornu posterius medullae spinalis" EXACT LATIN [Wikipedia:Posterior_horn_of_spinal_cord] +synonym: "cornu posterius medullae spinalis" EXACT OMO:0003011 [Wikipedia:Posterior_horn_of_spinal_cord] synonym: "dorsal gray column of spinal cord" EXACT [FMA:256530] synonym: "dorsal gray horn" EXACT [BIRNLEX:2667] synonym: "dorsal gray matter of spinal cord" EXACT [FMA:256530] @@ -190491,8 +190794,8 @@ synonym: "anterior gray horn of spinal cord" EXACT [FMA:256541] synonym: "anterior grey column of spinal cord" EXACT [] synonym: "anterior horn" EXACT [BIRNLEX:2668] synonym: "anterior horn (spinal cord)" RELATED [Wikipedia:Anterior_horn_of_spinal_cord] -synonym: "columna grisea anterior medullae spinalis" EXACT LATIN [FMA:256541, FMA:TA] -synonym: "cornu anterius medullae spinalis" RELATED LATIN [Wikipedia:Anterior_horn_of_spinal_cord] +synonym: "columna grisea anterior medullae spinalis" EXACT OMO:0003011 [FMA:256541, FMA:TA] +synonym: "cornu anterius medullae spinalis" RELATED OMO:0003011 [Wikipedia:Anterior_horn_of_spinal_cord] synonym: "spinal cord anterior horn" EXACT [BIRNLEX:2668] synonym: "spinal cord ventral horn" EXACT [] synonym: "ventral gray column of spinal cord" EXACT [FMA:256541] @@ -190543,7 +190846,7 @@ synonym: "dorsal spinal nerve root" EXACT [FMA:5980] synonym: "dorsal spinal root" EXACT [] synonym: "posterior root of spinal nerve" EXACT [Wikipedia:Posterior_root_of_spinal_nerve] synonym: "radix dorsalis" EXACT [ZFA:0000652] -synonym: "radix posterior" RELATED LATIN [Wikipedia:Posterior_root_of_spinal_nerve] +synonym: "radix posterior" RELATED OMO:0003011 [Wikipedia:Posterior_root_of_spinal_nerve] synonym: "radix posterior (nervus spinalis)" EXACT [FMA:5980] synonym: "radix posterior nervi spinalis" RELATED [BTO:0000360] synonym: "radix sensoria (nervus spinalis)" EXACT [FMA:5980] @@ -190578,8 +190881,8 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "bulbus olfactorius" EXACT [Wikipedia:Olfactory_bulb] -synonym: "bulbus olfactorius" RELATED LATIN [Wikipedia:Olfactory_bulb] -synonym: "bulbus olfactorius (Morgagni)" RELATED LATIN [NeuroNames:279] +synonym: "bulbus olfactorius" RELATED OMO:0003011 [Wikipedia:Olfactory_bulb] +synonym: "bulbus olfactorius (Morgagni)" RELATED OMO:0003011 [NeuroNames:279] synonym: "olfactory lobe" RELATED [ZFA:0000402] synonym: "olfactory lobe (Barr & Kiernan)" RELATED [NeuroNames:279] xref: AAO:0010165 @@ -190641,9 +190944,9 @@ subset: pheno_slim subset: uberon_slim synonym: "olfactory peduncle" RELATED [BTO:0003647] synonym: "olfactory stalk" RELATED [NeuroNames:283] -synonym: "pedunclulus olfactorius" RELATED LATIN [NeuroNames:283] -synonym: "tractus olfactorium" RELATED LATIN [NeuroNames:283] -synonym: "tractus olfactorius" RELATED LATIN [BTO:0003647, Wikipedia:Olfactory_tract] +synonym: "pedunclulus olfactorius" RELATED OMO:0003011 [NeuroNames:283] +synonym: "tractus olfactorium" RELATED OMO:0003011 [NeuroNames:283] +synonym: "tractus olfactorius" RELATED OMO:0003011 [BTO:0003647, Wikipedia:Olfactory_tract] xref: BAMS:olf xref: BIRNLEX:1663 xref: BTO:0003647 @@ -190688,7 +190991,7 @@ synonym: "organum olfactorium" RELATED [BTO:0001772] synonym: "primary olfactory organ" NARROW [] xref: AAO:0010180 xref: BTO:0001772 -xref: FBbt:00005158 +xref: FBbt:00005158 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:77659 xref: VHOG:0000287 xref: XAO:0000273 @@ -190707,7 +191010,7 @@ name: periventricular zone of hypothalamus namespace: uberon synonym: "hypothalamus periventricular zone" EXACT [] synonym: "periventricular zone of the hypothalamus" RELATED [BAMS:PVZ] -synonym: "zona periventricularis hypothalamicae" EXACT LATIN [FMA:77682, FMA:TA] +synonym: "zona periventricularis hypothalamicae" EXACT OMO:0003011 [FMA:77682, FMA:TA] xref: BAMS:PVZ xref: EMAPA:35421 xref: FMA:77682 @@ -190725,7 +191028,7 @@ namespace: uberon synonym: "hypothalamic medial zone behavioral control column" RELATED [BAMS:MEZ] synonym: "hypothalamus medial zone" EXACT [] synonym: "medial zone of the hypothalamus" RELATED [BAMS:MEZ, BAMS:MZ] -synonym: "zona medialis hypothalamicae" EXACT LATIN [FMA:77683, FMA:TA] +synonym: "zona medialis hypothalamicae" EXACT OMO:0003011 [FMA:77683, FMA:TA] xref: BAMS:MEZ xref: BAMS:MZ xref: EMAPA:35419 @@ -190813,7 +191116,7 @@ subset: pheno_slim subset: uberon_slim synonym: "psalterial cord" EXACT [MP:0000048] synonym: "stria vascularis" EXACT [] -synonym: "stria vascularis ductus cochlearis" RELATED LATIN [BTO:0001819] +synonym: "stria vascularis ductus cochlearis" RELATED OMO:0003011 [BTO:0001819] synonym: "stria vascularis of cochlea" EXACT [FMA:77832] synonym: "vascular stria of cochlear duct" RELATED [BTO:0001819] synonym: "vascular stripe of cochlear duct" EXACT [MP:0000048] @@ -191023,6 +191326,7 @@ xref: EHDAA2:0000262 xref: EMAPA:35751 xref: FMA:79789 xref: MA:0002458 +xref: MESH:D003053 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} xref: Wikipedia:Scala_media is_a: UBERON:0011060 {source="MA"} ! perilymphatic channel is_a: UBERON:0013685 ! foramen of skull @@ -191039,7 +191343,7 @@ def: "The mesentery that originates from the dorsal side of the peritoneal cavit subset: uberon_slim subset: vertebrate_core synonym: "dorsal mesogastrium" RELATED [Wikipedia:Dorsal_mesentery] -synonym: "mesenterium dorsale commune" RELATED LATIN [Wikipedia:Dorsal_mesentery] +synonym: "mesenterium dorsale commune" RELATED OMO:0003011 [Wikipedia:Dorsal_mesentery] xref: EHDAA2:0004560 xref: EHDAA:3019 xref: EHDAA:3033 @@ -191070,12 +191374,12 @@ subset: uberon_slim subset: vertebrate_core synonym: "accessory medullary lamina of pallidum" RELATED [NeuroNames:236] synonym: "brain stem" EXACT [ABA:BS] -synonym: "lamella pallidi incompleta" RELATED LATIN [NeuroNames:236] -synonym: "lamina medullaris accessoria" RELATED LATIN [NeuroNames:236] -synonym: "lamina medullaris incompleta pallidi" RELATED LATIN [NeuroNames:236] -synonym: "lamina pallidi incompleta" RELATED LATIN [NeuroNames:236] -synonym: "truncus encephali" EXACT LATIN [Wikipedia:Brainstem] -synonym: "truncus encephalicus" RELATED LATIN [BTO:0000146] +synonym: "lamella pallidi incompleta" RELATED OMO:0003011 [NeuroNames:236] +synonym: "lamina medullaris accessoria" RELATED OMO:0003011 [NeuroNames:236] +synonym: "lamina medullaris incompleta pallidi" RELATED OMO:0003011 [NeuroNames:236] +synonym: "lamina pallidi incompleta" RELATED OMO:0003011 [NeuroNames:236] +synonym: "truncus encephali" EXACT OMO:0003011 [Wikipedia:Brainstem] +synonym: "truncus encephalicus" RELATED OMO:0003011 [BTO:0000146] xref: BAMS:BS xref: BIRNLEX:1565 xref: BTO:0000146 @@ -191120,7 +191424,7 @@ subset: uberon_slim synonym: "alveoli" RELATED OMO:0003004 [BTO:0000060] synonym: "alveolus" BROAD [] synonym: "alveolus pulmonis" EXACT [Wikipedia:Pulmonary_alveolus] -synonym: "alveolus pulmonis" RELATED LATIN [Wikipedia:Pulmonary_alveolus] +synonym: "alveolus pulmonis" RELATED OMO:0003011 [Wikipedia:Pulmonary_alveolus] synonym: "lung alveolus" EXACT [] synonym: "pulmonary alveolus" EXACT [FMA:7318] synonym: "respiratory alveoli" RELATED OMO:0003004 [] @@ -191201,7 +191505,7 @@ def: "An anatomical structure which consists of juxtaglomerular cells, extraglom subset: human_reference_atlas subset: pheno_slim subset: uberon_slim -synonym: "complexus juxtaglomerularis" EXACT LATIN [] +synonym: "complexus juxtaglomerularis" EXACT OMO:0003011 [] synonym: "juxtaglomerular complex" EXACT [MP:0002829] xref: BTO:0005157 xref: EMAPA:30449 @@ -191343,8 +191647,8 @@ def: "Regional part of fornix consisting of a prominent white matter structure a subset: pheno_slim synonym: "fimbria" BROAD [BIRNLEX:1502] synonym: "fimbria (Vieussens)" RELATED [NeuroNames:187] -synonym: "fimbria fornicis" RELATED LATIN [NeuroNames:187] -synonym: "fimbria hippocampi" RELATED LATIN [NeuroNames:187, Wikipedia:Fimbria_of_hippocampus] +synonym: "fimbria fornicis" RELATED OMO:0003011 [NeuroNames:187] +synonym: "fimbria hippocampi" RELATED OMO:0003011 [NeuroNames:187, Wikipedia:Fimbria_of_hippocampus] synonym: "fimbria hippocampus" EXACT [] synonym: "fimbria of fornix" RELATED [NeuroNames:187] synonym: "fimbria of hippocampus" EXACT [FMA:83866] @@ -191383,8 +191687,8 @@ alt_id: UBERON:0005369 def: "A cytoarchitectural term denoting the layer of the hippocampus in which pyramidal cells are predominant. Its location is superficial to the Stratum oriens; it is deep to the Stratum radiatum in area CA1 and area CA2 and deep to the Stratum lucidum in area CA3 (Stephan-75) (NeuroNames)." [BIRNLEX:1444] comment: EDITOR_NOTE this layer changes in its depthwise spatial relation across its extent subset: pheno_slim -synonym: "gyrus occipitalis inferior" RELATED LATIN [NeuroNames:156] -synonym: "gyrus occipitalis tertius" RELATED LATIN [NeuroNames:156] +synonym: "gyrus occipitalis inferior" RELATED OMO:0003011 [NeuroNames:156] +synonym: "gyrus occipitalis tertius" RELATED OMO:0003011 [NeuroNames:156] synonym: "hippocampal pyramidal cell layer" RELATED [] synonym: "hippocampal pyramidal layer" RELATED [] synonym: "hippocampus pyramidal cell layer" RELATED [] @@ -191418,10 +191722,10 @@ subset: pheno_slim subset: uberon_slim synonym: "mesencephalic tectum" EXACT [ZFA:0000445] synonym: "neuraxis tectum" EXACT [] -synonym: "t. mesencephali" RELATED LATIN [Wikipedia:Midbrain_tectum] +synonym: "t. mesencephali" RELATED OMO:0003011 [Wikipedia:Midbrain_tectum] synonym: "tectum" EXACT [] synonym: "tectum mesencephali" EXACT [BTO:0001793] -synonym: "tectum mesencephalicum" RELATED LATIN [NeuroNames:465] +synonym: "tectum mesencephalicum" RELATED OMO:0003011 [NeuroNames:465] synonym: "tectum of midbrain" RELATED [NeuroNames:465] xref: BAMS:MTec xref: BAMS:Tec @@ -191463,7 +191767,7 @@ synonym: "grey substance of spinal cord" EXACT [] synonym: "spinal cord gray matter" EXACT [OBOL:automatic] synonym: "spinal cord grey matter" EXACT [] synonym: "spinal cord grey substance" EXACT [OBOL:automatic] -synonym: "substantia grisea medullae spinalis" EXACT LATIN [FMA:256580, FMA:TA] +synonym: "substantia grisea medullae spinalis" EXACT OMO:0003011 [FMA:256580, FMA:TA] xref: BAMS:Scgrey xref: DHBA:146035048 xref: EMAPA:35792 @@ -191491,7 +191795,7 @@ synonym: "CNS tract/commissure" EXACT [ZFA:0001682] synonym: "CNS tracts and commissures" RELATED [TAO:0000145] synonym: "CNS white matter" RELATED [TAO:0002143] synonym: "neuronal white matter" EXACT [AEO:0001011] -synonym: "substantia alba" RELATED LATIN [Wikipedia:White_matter] +synonym: "substantia alba" RELATED OMO:0003011 [Wikipedia:White_matter] synonym: "white mater" RELATED [VHOG:0001764] synonym: "white matter of neuraxis" EXACT [FMA:83929] synonym: "white substance" EXACT [] @@ -191501,7 +191805,7 @@ xref: EMAPA:35927 xref: FMA:83929 xref: HBA:9218 xref: MA:0001135 -xref: MESH:D066127 +xref: MESH:D066127 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: NCIT:C33892 xref: neuronames:2870 xref: NLX:412 @@ -191532,7 +191836,7 @@ subset: pheno_slim synonym: "spinal cord white matter" EXACT [] synonym: "spinal cord white matter of neuraxis" EXACT [OBOL:automatic] synonym: "spinal cord white substance" EXACT [OBOL:automatic] -synonym: "substantia alba medullae spinalis" EXACT LATIN [FMA:83945, FMA:TA] +synonym: "substantia alba medullae spinalis" EXACT OMO:0003011 [FMA:83945, FMA:TA] synonym: "white matter of neuraxis of spinal cord" EXACT [OBOL:automatic] synonym: "white substance of spinal cord" EXACT [OBOL:automatic] xref: BAMS:SCwhite @@ -191653,7 +191957,7 @@ synonym: "ventral body cavity" NARROW [NCBITaxon:7742] xref: AEO:0000186 xref: BTO:0001707 xref: EHDAA2:0000267 -xref: FBbt:00005060 +xref: FBbt:00005060 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:85006 xref: galen:BodyCavity xref: NCIT:C25444 @@ -191755,7 +192059,7 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "embryonic notocord" EXACT [] -synonym: "notochorda" RELATED LATIN [Wikipedia:Notochord] +synonym: "notochorda" RELATED OMO:0003011 [Wikipedia:Notochord] synonym: "notocord" EXACT [ZFA:0000135] xref: AAO:0000327 xref: BTO:0001768 @@ -191815,7 +192119,7 @@ synonym: "epithelial somite" RELATED [https://github.com/obophenotype/uberon/wik synonym: "mesodermal cluster" BROAD [GO:0001756] synonym: "somites" RELATED OMO:0003004 [] synonym: "somitic mesoderm" RELATED [] -synonym: "somitus" RELATED LATIN [Wikipedia:Somite] +synonym: "somitus" RELATED OMO:0003011 [Wikipedia:Somite] xref: AAO:0010569 xref: AEO:0001015 xref: BTO:0001558 @@ -191890,10 +192194,10 @@ subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "birth cord" RELATED [Wikipedia:Umbilical_cord] -synonym: "chorda umbilicalis" EXACT LATIN [MP:0012134] +synonym: "chorda umbilicalis" EXACT OMO:0003011 [MP:0012134] synonym: "connecting stalk" RELATED [] -synonym: "funiculus umbilicalis" EXACT LATIN [MP:0012134] -synonym: "funiculus umbilicalis" RELATED LATIN [Wikipedia:Umbilical_cord] +synonym: "funiculus umbilicalis" EXACT OMO:0003011 [MP:0012134] +synonym: "funiculus umbilicalis" RELATED OMO:0003011 [Wikipedia:Umbilical_cord] synonym: "yolk stalk" RELATED [BTO:0001415] xref: BTO:0001415 xref: CALOHA:TS-1078 @@ -192100,7 +192404,7 @@ comment: Gene notes: Many factors and genes, such as Pax3 (Tremblay et al., 1995 subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "crista neuralis" RELATED LATIN [Wikipedia:Neural_crest] +synonym: "crista neuralis" RELATED OMO:0003011 [Wikipedia:Neural_crest] synonym: "NC" EXACT OMO:0003000 [XAO:0000048] synonym: "neural crest material" RELATED [VHOG:0000057] xref: AAO:0010578 @@ -192189,7 +192493,7 @@ namespace: uberon def: "Embryonic ectoderm that gives rise to nervous tissue." [Wikipedia:Neuroectoderm] subset: uberon_slim subset: vertebrate_core -synonym: "epithelium tubi neuralis; neuroectoderma" RELATED LATIN [Wikipedia:Neuroectoderm] +synonym: "epithelium tubi neuralis; neuroectoderma" RELATED OMO:0003011 [Wikipedia:Neuroectoderm] synonym: "neuaral ectoderm" RELATED [] synonym: "neural ectoderm" EXACT [] synonym: "neuroectoderm" EXACT [] @@ -192203,7 +192507,7 @@ xref: EHDAA:1498 xref: EHDAA:255 xref: EMAPA:16073 xref: EV:0100004 -xref: FBbt:00001057 +xref: FBbt:00001057 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:87657 xref: MAT:0000176 xref: MIAA:0000176 @@ -192350,10 +192654,10 @@ synonym: "cardiac conduction system" EXACT [] synonym: "cardiac impulse conducting system" EXACT [GO:0003161] synonym: "cardionector" EXACT [] synonym: "central conduction system" RELATED [] -synonym: "complexus stimulans cordis" EXACT LATIN [FMA:9476, FMA:TA] +synonym: "complexus stimulans cordis" EXACT OMO:0003011 [FMA:9476, FMA:TA] synonym: "heart conduction system" EXACT [GO:0003161] synonym: "impulse conducting system" EXACT [MA:0000094] -synonym: "systema conducente cordis" EXACT LATIN [FMA:9476, FMA:TA] +synonym: "systema conducente cordis" EXACT OMO:0003011 [FMA:9476, FMA:TA] xref: EFO:0003909 xref: EHDAA2:0004185 xref: EMAPA:35428 @@ -192389,8 +192693,8 @@ subset: vertebrate_core synonym: "cardiac pacemaker" EXACT [FMA:9477] synonym: "Koch's node" EXACT [FMA:9477] synonym: "node of Keith-Flack" EXACT [FMA:9477] -synonym: "nodus sinuatrialis" EXACT LATIN [FMA:9477, FMA:TA] -synonym: "nodus sinuatrialis" RELATED LATIN [Wikipedia:Sinoatrial_node] +synonym: "nodus sinuatrialis" EXACT OMO:0003011 [FMA:9477, FMA:TA] +synonym: "nodus sinuatrialis" RELATED OMO:0003011 [Wikipedia:Sinoatrial_node] synonym: "SA nodal muscle tissue" EXACT [FMA:9477] synonym: "SA node" EXACT [FMA:9477] synonym: "sinoatrial node" EXACT [FMA:9477] @@ -192442,8 +192746,8 @@ synonym: "AV nodal muscle tissue" EXACT [FMA:9478] synonym: "AV node" EXACT [FMA:9478, MA:0000095] synonym: "downstream pacemaker" RELATED [ZFA:0005070] synonym: "node of Tawara" EXACT [FMA:9478] -synonym: "nodus atrioventricularis" EXACT LATIN [FMA:TA] -synonym: "nodus atrioventricularis" RELATED LATIN [Wikipedia:Atrioventricular_node] +synonym: "nodus atrioventricularis" EXACT OMO:0003011 [FMA:TA] +synonym: "nodus atrioventricularis" RELATED OMO:0003011 [Wikipedia:Atrioventricular_node] xref: BTO:0005689 xref: EFO:0000276 xref: EHDAA2:0004183 @@ -192488,7 +192792,7 @@ synonym: "atrioventricular fasciculus" EXACT [FMA:9484] synonym: "AV bundle" EXACT [] synonym: "AVB" EXACT OMO:0003000 [] synonym: "bundle of His" EXACT [FMA:9484, GO:0003166] -synonym: "fasciculus atrioventricularis" EXACT LATIN [Wikipedia:Bundle_of_His] +synonym: "fasciculus atrioventricularis" EXACT OMO:0003011 [Wikipedia:Bundle_of_His] synonym: "His bundle" EXACT [] xref: EMAPA:35152 xref: FMA:9484 @@ -192519,7 +192823,7 @@ subset: pheno_slim subset: uberon_slim synonym: "cardiac Purkinje fiber" EXACT [BTO:0001735, GO:0003165] synonym: "heart Purkinje fiber" RELATED [BTO:0001735] -synonym: "myofibra conducens cardiacus" EXACT LATIN [] +synonym: "myofibra conducens cardiacus" EXACT OMO:0003011 [] synonym: "Purkinje fiber" EXACT [FMA:9492, MA:0000096] synonym: "subendocardial branch" EXACT [Wikipedia:Purkinje_fiber] xref: BTO:0001735 @@ -192577,7 +192881,7 @@ name: serous pericardium namespace: uberon def: "Serous membrane which is divided into parietal and visceral serous pericardium." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Serous_pericardium] subset: uberon_slim -synonym: "pericardium serosum" RELATED LATIN [Wikipedia:Serous_pericardium] +synonym: "pericardium serosum" RELATED OMO:0003011 [Wikipedia:Serous_pericardium] synonym: "serous portion of pericardium" EXACT [FMA:9582] xref: EMAPA:19030 xref: FMA:9582 @@ -192635,7 +192939,7 @@ def: "Membrane organ which is attached to the pericardial sac proper and the cen subset: organ_slim subset: uberon_slim synonym: "fibrous portion of pericardium" EXACT [] -synonym: "pericardium fibrosum" RELATED LATIN [Wikipedia:Fibrous_pericardium] +synonym: "pericardium fibrosum" RELATED OMO:0003011 [Wikipedia:Fibrous_pericardium] xref: EMAPA:19029 xref: FMA:9586 xref: MA:0002738 @@ -192812,7 +193116,7 @@ synonym: "eardrum" EXACT [] synonym: "lateral wall of tympanic cavity" EXACT [] synonym: "membranous wall of tympanic cavity" EXACT [] synonym: "myrinx" EXACT [] -synonym: "paries membranaceus cavi tympani" EXACT LATIN [FMA:9595, FMA:TA] +synonym: "paries membranaceus cavi tympani" EXACT OMO:0003011 [FMA:9595, FMA:TA] synonym: "Rivinus' membrane" EXACT [] synonym: "tympanum" RELATED [Wikipedia:Tympanic_membrane] xref: EMAPA:19062 @@ -192851,7 +193155,7 @@ subset: organ_slim subset: pheno_slim subset: uberon_slim synonym: "ducted gland" EXACT [AEO:0000097] -synonym: "glandula exocrina" EXACT LATIN [Wikipedia:Exocrine_gland] +synonym: "glandula exocrina" EXACT OMO:0003011 [Wikipedia:Exocrine_gland] xref: AEO:0000097 xref: BTO:0000765 xref: CALOHA:TS-2012 @@ -192885,7 +193189,7 @@ subset: organ_slim subset: pheno_slim subset: uberon_slim synonym: "male prostate" EXACT [PMID:10668204] -synonym: "prostata" RELATED LATIN [Wikipedia:Prostate] +synonym: "prostata" RELATED OMO:0003011 [Wikipedia:Prostate] synonym: "prostate" EXACT [] xref: BTO:0001129 xref: CALOHA:TS-0828 @@ -192925,7 +193229,7 @@ subset: uberon_slim synonym: "ductless gland" EXACT [AEO:0000098] synonym: "ductless gland" RELATED [Wikipedia:Ductless_gland] synonym: "glandula endocrina" EXACT [] -synonym: "glandulae endocrinae" RELATED LATIN [Wikipedia:Endocrine_gland] +synonym: "glandulae endocrinae" RELATED OMO:0003011 [Wikipedia:Endocrine_gland] xref: AEO:0000098 xref: BTO:0001488 xref: CALOHA:TS-1300 @@ -192960,8 +193264,8 @@ synonym: "adrenal medulla cell" RELATED [] synonym: "atrabiliary capsule" RELATED [BTO:0000047] synonym: "epinephric gland" RELATED [Wikipedia:Adrenal_gland] synonym: "epinephros" RELATED [BTO:0000047] -synonym: "glandula adrenalis" EXACT LATIN [Wikipedia:Adrenal_gland] -synonym: "glandula suprarenalis" EXACT LATIN [Wikipedia:Adrenal_gland] +synonym: "glandula adrenalis" EXACT OMO:0003011 [Wikipedia:Adrenal_gland] +synonym: "glandula suprarenalis" EXACT OMO:0003011 [Wikipedia:Adrenal_gland] synonym: "glandula suprarenalis" RELATED [BTO:0000047] synonym: "interrenal gland" RELATED HOMOLOGY [GO:0030325] synonym: "suprarenal capsule" RELATED [BTO:0000047] @@ -193066,8 +193370,8 @@ subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "medulla of bone" RELATED [BTO:0000141] -synonym: "medulla ossea" EXACT LATIN [BTO:0000141, FMA:9608] -synonym: "medulla ossium" EXACT LATIN [BTO:0000141, Wikipedia:Bone_marrow] +synonym: "medulla ossea" EXACT OMO:0003011 [BTO:0000141, FMA:9608] +synonym: "medulla ossium" EXACT OMO:0003011 [BTO:0000141, Wikipedia:Bone_marrow] synonym: "medullary bone" RELATED [] xref: AAO:0011007 xref: BTO:0000141 @@ -193275,7 +193579,7 @@ namespace: uberon def: "A large superficial muscle that extends longitudinally from the occipital bone to the lower thoracic vertebrae and laterally to the spine of the scapula (shoulder blade). Its functions are to move the scapulae and support the arm. The trapezius has three functional regions: the superior region (descending part), which supports the weight of the arm; the intermediate region (transverse part), which retracts the scapulae; and the inferior region (ascending part), which medially rotates and depresses the scapulae. [WP,unvetted]." [Wikipedia:Trapezius_muscle] subset: human_reference_atlas subset: uberon_slim -synonym: "musculus trapezius" RELATED LATIN [Wikipedia:Trapezius_muscle] +synonym: "musculus trapezius" RELATED OMO:0003011 [Wikipedia:Trapezius_muscle] synonym: "spinotrapezius" RELATED [Wikipedia:Trapezius_muscle] synonym: "trapezius" EXACT [] xref: EMAPA:18183 @@ -193308,7 +193612,7 @@ subset: human_reference_atlas subset: organ_slim subset: pheno_slim subset: uberon_slim -synonym: "musculus pectoralis major" RELATED LATIN [Wikipedia:Pectoralis_major_muscle] +synonym: "musculus pectoralis major" RELATED OMO:0003011 [Wikipedia:Pectoralis_major_muscle] synonym: "pectoralis major muscle" EXACT [] synonym: "pectoralis major muscle structure" EXACT [] xref: EHDAA2:0001424 @@ -193416,7 +193720,7 @@ subset: pheno_slim subset: uberon_slim synonym: "antebrachial region" EXACT [] synonym: "antebrachium" EXACT [VSAO:0005058, Wikipedia:Forearm] -synonym: "antebrachium" RELATED LATIN [Wikipedia:Forearm] +synonym: "antebrachium" RELATED OMO:0003011 [Wikipedia:Forearm] synonym: "antibrachium" EXACT [] synonym: "arm middle limb segment" EXACT [OBOL:automatic] synonym: "arm zeugopod" EXACT [OBOL:automatic] @@ -193434,7 +193738,7 @@ synonym: "middle limb segment of arm" EXACT [OBOL:automatic] synonym: "middle limb segment of brachial region" EXACT [OBOL:automatic] synonym: "middle limb segment of forelimb" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "middle limb segment of proximal segment of free upper limb" EXACT [OBOL:automatic] -synonym: "regio antebrachialis" EXACT LATIN [FMA:9663, FMA:TA] +synonym: "regio antebrachialis" EXACT OMO:0003011 [FMA:9663, FMA:TA] synonym: "wing zeugopod" NARROW SENSU [NCBITaxon:8782, OBOL:automatic] synonym: "zeugopod of arm" EXACT [] synonym: "zeugopod of brachial region" EXACT [OBOL:automatic] @@ -193616,7 +193920,7 @@ def: "Lymph is the fluid that is formed when interstitial fluid enters the condu subset: efo_slim subset: pheno_slim subset: uberon_slim -synonym: "lympha" RELATED LATIN [Wikipedia:Lymph] +synonym: "lympha" RELATED OMO:0003011 [Wikipedia:Lymph] xref: BTO:0000855 xref: CALOHA:TS-0580 xref: EFO:0000871 @@ -193646,7 +193950,7 @@ namespace: uberon def: "The paired channels leading from the lacrimal sacs to the inferior meatus of the nose, through which tears are conducted through the nasal cavity." [ISBN:0-683-40008-8, MP:0008969] subset: pheno_slim subset: uberon_slim -synonym: "d. nasolacrimalis" RELATED LATIN [Wikipedia:Nasolacrimal_duct] +synonym: "d. nasolacrimalis" RELATED OMO:0003011 [Wikipedia:Nasolacrimal_duct] synonym: "lacrimal duct" RELATED [PMID:30285382] synonym: "nasolacrimal duct - posterior naris" BROAD [VHOG:0000664] synonym: "tear duct" RELATED [Wikipedia:Nasolacrimal_duct] @@ -193736,7 +194040,7 @@ synonym: "vomer bone" EXACT [] xref: AAO:0000633 xref: FMA:9710 xref: MA:0001496 -xref: MESH:D055172 +xref: MESH:D055172 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: NCIT:C33888 xref: SCTID:272678009 xref: TAO:0000308 @@ -193812,7 +194116,7 @@ def: "The outer serous membrane of the pulmonary pleural." [UBERON:cjm, Wikipedi comment: the part of the pleura external to the visceral pleura. It lines the inner surface of the chest wall, covers the diaphragm, and is reflected over the structures occupying the middle of the thorax subset: pheno_slim subset: uberon_slim -synonym: "pleura parietalis" RELATED LATIN [Wikipedia:Parietal_pleura] +synonym: "pleura parietalis" RELATED OMO:0003011 [Wikipedia:Parietal_pleura] xref: EMAPA:16776 xref: FMA:9733 xref: MA:0002488 @@ -193840,8 +194144,8 @@ subset: pheno_slim subset: uberon_slim synonym: "lung mesothelium" RELATED [EHDAA2:0002205] synonym: "lung pleura" RELATED [] -synonym: "pleura pulmonalis" EXACT LATIN [FMA:9734, FMA:TA] -synonym: "pleura visceralis" EXACT LATIN [Wikipedia:Visceral_pleura] +synonym: "pleura pulmonalis" EXACT OMO:0003011 [FMA:9734, FMA:TA] +synonym: "pleura visceralis" EXACT OMO:0003011 [Wikipedia:Visceral_pleura] synonym: "pleura visceralis (pulmonalis)" EXACT [] synonym: "pulmonary pleura" RELATED INCONSISTENT [FMA:9734] synonym: "pulmonary visceral pleura" EXACT [] @@ -193873,9 +194177,9 @@ namespace: uberon def: "The fluid-filled cavity that lies between the visceral and parietal pleurae." [https://github.com/obophenotype/uberon/issues/86, Wikipedia:Pleural_cavity] subset: pheno_slim subset: uberon_slim -synonym: "cavitas pleuralis" EXACT LATIN [Wikipedia:Pleural_cavity] -synonym: "cavitum pleuralae" RELATED LATIN [Wikipedia:Pleural_cavity] -synonym: "cavitum pleurale" RELATED LATIN [Wikipedia:Pleural_cavity] +synonym: "cavitas pleuralis" EXACT OMO:0003011 [Wikipedia:Pleural_cavity] +synonym: "cavitum pleuralae" RELATED OMO:0003011 [Wikipedia:Pleural_cavity] +synonym: "cavitum pleurale" RELATED OMO:0003011 [Wikipedia:Pleural_cavity] xref: BTO:0004422 xref: EHDAA2:0001475 xref: EMAPA:16773 @@ -194014,7 +194318,7 @@ def: "Parietal serous membrane which is part of the pericardium and forms the ou subset: pheno_slim subset: uberon_slim synonym: "lamina parietalis (pericardii serosum)" EXACT [] -synonym: "lamina parietalis pericardii" EXACT LATIN [FMA:9870, FMA:TA] +synonym: "lamina parietalis pericardii" EXACT OMO:0003011 [FMA:9870, FMA:TA] synonym: "parietal layer of serous pericardium" EXACT [] synonym: "parietal pericardium" EXACT [VHOG:0000537] synonym: "pericardial sac" RELATED INCONSISTENT [DOI:10.5962/bhl.title.1013] @@ -194044,7 +194348,7 @@ subset: uberon_slim xref: BTO:0001016 xref: FMA:9887 xref: MA:0002530 -xref: MESH:D000069236 +xref: MESH:D000069236 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: Wikipedia:Pericardial_fluid is_a: UBERON:0007794 {source="FMA"} ! secretion of serous gland is_a: UBERON:0036217 ! coelomic fluid @@ -194065,7 +194369,7 @@ synonym: "ANS" RELATED OMO:0003000 [] synonym: "autonomic division of peripheral nervous system" EXACT [FMA:65553] synonym: "autonomic part of peripheral nervous system" EXACT [FMA:65553] synonym: "divisio autonomica systematis nervosi peripherici" EXACT [FMA:TA] -synonym: "divisio autonomica systematis nervosi peripherici" RELATED LATIN [Wikipedia:Autonomic_nervous_system] +synonym: "divisio autonomica systematis nervosi peripherici" RELATED OMO:0003011 [Wikipedia:Autonomic_nervous_system] synonym: "pars autonomica systematis nervosi peripherici" EXACT [FMA:TA] synonym: "peripheral autonomic nervous system" EXACT [FMA:65553] synonym: "visceral nervous system" EXACT [] @@ -194079,6 +194383,7 @@ xref: EHDAA:3767 xref: EMAPA:16984 xref: FMA:65553 xref: GAID:706 +xref: IDOMAL:0002126 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} xref: MA:0000219 xref: MESH:D001341 xref: NCIT:C12673 @@ -194143,7 +194448,7 @@ subset: vertebrate_core synonym: "vertebra bone" EXACT [] synonym: "vertebrae" EXACT OMO:0003004 [PHENOSCAPE:ad] xref: AAO:0000691 -xref: BTO:0006196 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: BTO:0006196 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: CALOHA:TS-2352 xref: EFO:0001371 xref: EMAPA:32740 @@ -194179,7 +194484,7 @@ subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "cervical vertebrae" EXACT OMO:0003004 [] -synonym: "vertebrae cervicales" RELATED LATIN [Wikipedia:Cervical_vertebrae] +synonym: "vertebrae cervicales" RELATED OMO:0003011 [Wikipedia:Cervical_vertebrae] xref: EMAPA:17674 xref: FMA:9915 xref: GAID:235 @@ -194242,7 +194547,7 @@ synonym: "body surface" RELATED [] synonym: "dermal system" RELATED [MIAA:0000033] synonym: "external covering of organism" RELATED [] synonym: "integumentary system" EXACT [FMA:72979] -synonym: "integumentum commune" RELATED LATIN [Wikipedia:Integumentary_system] +synonym: "integumentum commune" RELATED OMO:0003011 [Wikipedia:Integumentary_system] synonym: "organism surface" RELATED [EHDAA2:0003154] synonym: "surface" RELATED [BILA:0000118] xref: AEO:0000154 @@ -194255,7 +194560,7 @@ xref: EHDAA2_RETIRED:0003154 xref: EHDAA:6520 xref: EMAPA:17524 xref: EV:0100151 -xref: FBbt:00004969 +xref: FBbt:00004969 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:72979 xref: galen:Surface xref: HAO:0000421 @@ -194358,7 +194663,7 @@ name: skin gland namespace: uberon def: "A gland that is part of a skin of body [Automatically generated definition]." [OBOL:automatic] subset: organ_slim -synonym: "glandulae cutis" EXACT LATIN [FMA:71878, FMA:TA] +synonym: "glandulae cutis" EXACT OMO:0003011 [FMA:71878, FMA:TA] synonym: "set of skin glands" RELATED [FMA:71878] synonym: "skin glands" RELATED OMO:0003004 [] synonym: "skin glands set" RELATED OMO:0003004 [] @@ -194384,7 +194689,7 @@ subset: uberon_slim synonym: "basal ganglia" RELATED OMO:0003004 [] synonym: "basal ganglion of telencephalon" EXACT [] synonym: "basal nucleus" RELATED [MA:0000184] -synonym: "nuclei basales" RELATED LATIN [Wikipedia:Basal_ganglia] +synonym: "nuclei basales" RELATED OMO:0003011 [Wikipedia:Basal_ganglia] xref: BTO:0000235 xref: CALOHA:TS-1149 xref: DHBA:10332 @@ -194406,7 +194711,7 @@ subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "archipallium" RELATED [MA:0000189] -synonym: "formatio hippocampi" RELATED LATIN [NeuroNames:177] +synonym: "formatio hippocampi" RELATED OMO:0003011 [NeuroNames:177] synonym: "hippocampus" NARROW INCONSISTENT [BTO:0000601, GO:0021766] synonym: "hippocampus (Crosby)" EXACT [] synonym: "major hippocampus" RELATED [BTO:0000601] @@ -194455,7 +194760,7 @@ synonym: "rhombencephalic vesicle" NARROW [ZFA:0000110] synonym: "ventricle IV" EXACT [ZFA:0000110] synonym: "ventricle of hindbrain" RELATED NON_MAMMAL [BTO:0003426] synonym: "ventricle of rhombencephalon" RELATED [BTO:0003426] -synonym: "ventriculus quartus" RELATED LATIN [Wikipedia:Fourth_ventricle] +synonym: "ventriculus quartus" RELATED OMO:0003011 [Wikipedia:Fourth_ventricle] xref: AAO:0011043 xref: BAMS:4V xref: BAMS:V4 @@ -194584,7 +194889,7 @@ def: "Visceral serous membrane which is continuous with the parietal serous peri subset: pheno_slim subset: uberon_slim synonym: "epicardium" RELATED [MA:0000484] -synonym: "lamina visceralis pericardii serosi" EXACT LATIN [Wikipedia:Epicardium] +synonym: "lamina visceralis pericardii serosi" EXACT OMO:0003011 [Wikipedia:Epicardium] synonym: "pericardium visceral mesothelium" RELATED [EMAPA:16589] synonym: "serous visceral pericardium" EXACT [] synonym: "visceral lamina of serous pericardium" EXACT [] @@ -194704,7 +195009,7 @@ subset: pheno_slim subset: uberon_slim synonym: "caudate putamen" RELATED [BIRNLEX:1672] synonym: "corpus striatum" RELATED [MA:0000891] -synonym: "corpus striatum (Zilles)" RELATED LATIN [NeuroNames:225] +synonym: "corpus striatum (Zilles)" RELATED OMO:0003011 [NeuroNames:225] synonym: "dorsal striatum" RELATED [BIRNLEX:1672] synonym: "neostriatum" EXACT [BIRNLEX:1672, GO:0021756, Wikipedia:Striatum] synonym: "neuraxis striatum" EXACT [FMA:83683] @@ -194754,7 +195059,7 @@ synonym: "cerebral hemisphere white matter" EXACT [] synonym: "cerebral white matter" EXACT [MA:0000945] synonym: "hemisphere white matter" RELATED [] synonym: "region of cerebral white matter" RELATED [FMA:256174] -synonym: "substantia medullaris cerebri" RELATED LATIN [NeuroNames:189] +synonym: "substantia medullaris cerebri" RELATED OMO:0003011 [NeuroNames:189] synonym: "white matter structure of cerebral hemisphere" EXACT [FMA:61822] xref: BAMS:cw xref: BIRNLEX:711 @@ -194810,7 +195115,7 @@ synonym: "choroid coat blood vessel" EXACT [OBOL:automatic] synonym: "choroidea blood vessel" EXACT [OBOL:automatic] synonym: "posterior uvea blood vessel" EXACT [OBOL:automatic] synonym: "set of choroid blood vessels" RELATED [FMA:76550] -synonym: "vasa sanguinea choroideae" EXACT LATIN [FMA:76550, FMA:TA] +synonym: "vasa sanguinea choroideae" EXACT OMO:0003011 [FMA:76550, FMA:TA] xref: EMAPA:17828 xref: FMA:76550 xref: MA:0001237 @@ -194826,7 +195131,7 @@ namespace: uberon def: "A region of the lens consisting of packed elongated enucleate cells packed with crystallin." [http://orcid.org/0000-0002-6601-2165] subset: human_reference_atlas subset: pheno_slim -synonym: "fibrae lentis" EXACT LATIN [FMA:76827, FMA:TA] +synonym: "fibrae lentis" EXACT OMO:0003011 [FMA:76827, FMA:TA] synonym: "lens fibers" EXACT [] synonym: "lens fibers set" EXACT [] synonym: "lens fibre" RELATED [EMAPA:17841] @@ -194866,7 +195171,7 @@ subset: pheno_slim subset: uberon_slim synonym: "knee bone" RELATED [FMA:24485] synonym: "knee cap" RELATED [Wikipedia:Patella] -synonym: "patella" RELATED LATIN [Wikipedia:Patella] +synonym: "patella" RELATED OMO:0003011 [Wikipedia:Patella] xref: EMAPA:35668 xref: FMA:24485 xref: GAID:203 @@ -194940,8 +195245,8 @@ subset: uberon_slim synonym: "endometrial gland" EXACT [BTO:0003433] synonym: "endometrial mucuous gland" EXACT [] synonym: "endometrium gland" EXACT [] -synonym: "glandulae uterinae" EXACT LATIN [FMA:71647, FMA:TA] -synonym: "glandulae uterinae" RELATED LATIN [Wikipedia:Uterine_glands] +synonym: "glandulae uterinae" EXACT OMO:0003011 [FMA:71647, FMA:TA] +synonym: "glandulae uterinae" RELATED OMO:0003011 [Wikipedia:Uterine_glands] synonym: "uterine gland" EXACT [] xref: BTO:0003433 xref: BTO:0004518 @@ -194970,8 +195275,8 @@ namespace: uberon def: "An artery that supplies the anterior chest wall and the breasts. It is a paired artery, with one running along each side of the sternum, to continue after its bifurcation as the superior epigastric and musculophrenic arteries. [WP,unvetted]." [Wikipedia:Internal_thoracic_artery] subset: human_reference_atlas subset: uberon_slim -synonym: "arteria mammaria interna" RELATED LATIN [Wikipedia:Internal_thoracic_artery] -synonym: "arteria thoracica interna" RELATED LATIN [Wikipedia:Internal_thoracic_artery] +synonym: "arteria mammaria interna" RELATED OMO:0003011 [Wikipedia:Internal_thoracic_artery] +synonym: "arteria thoracica interna" RELATED OMO:0003011 [Wikipedia:Internal_thoracic_artery] synonym: "internal mammary artery" EXACT PENDING_REVIEW [MA:0001982] synonym: "internal thoracic mammary artery" EXACT [] synonym: "mammary artery" RELATED [EMAPA:18617] @@ -195047,7 +195352,7 @@ namespace: uberon def: "A tributary of the iliac vein that drains the urinary bladder." [UBERON:cjm, Wikipedia:Vesical_veins] subset: human_reference_atlas subset: uberon_slim -synonym: "venae vesicales" EXACT LATIN [FMA:70911, FMA:TA] +synonym: "venae vesicales" EXACT OMO:0003011 [FMA:70911, FMA:TA] synonym: "vesical veins" EXACT OMO:0003004 [] synonym: "vesical veins set" EXACT [] xref: EMAPA:37205 {source="MA:th"} @@ -195098,7 +195403,7 @@ subset: vertebrate_core synonym: "lymphatic circulatory system" RELATED [https://orcid.org/0000-0002-6601-2165] synonym: "lymphatic drainage system" RELATED [https://orcid.org/0000-0002-6601-2165] synonym: "lymphatic system" NARROW [ZFA:0000385] -synonym: "systema lymphoideum" RELATED LATIN [Wikipedia:Lymphoid_system] +synonym: "systema lymphoideum" RELATED OMO:0003011 [Wikipedia:Lymphoid_system] xref: EHDAA2:0001043 xref: EHDAA:8677 xref: EMAPA:37664 {source="MA:th"} @@ -195160,7 +195465,7 @@ synonym: "esophageal mucosa" EXACT [] synonym: "esophageal mucous membrane" EXACT [] synonym: "esophagus mucosa" EXACT [FMA:62996] synonym: "esophagus mucous membrane" EXACT [OBOL:automatic] -synonym: "lamina muscularis mucosae oesophageae" EXACT LATIN [FMA:62996, FMA:TA] +synonym: "lamina muscularis mucosae oesophageae" EXACT OMO:0003011 [FMA:62996, FMA:TA] synonym: "mucosa of esophagus" EXACT [OBOL:automatic] synonym: "mucosa of oesophagus" EXACT [OBOL:automatic] synonym: "mucous membrane of esophagus" EXACT [] @@ -195170,14 +195475,14 @@ synonym: "oesophageal mucosa" EXACT [FMA:62996] synonym: "oesophagus mucosa" EXACT [] synonym: "oesophagus mucous membrane" EXACT [OBOL:automatic] synonym: "tunica mucosa esophagi" EXACT [] -synonym: "tunica mucosa oesophageae" EXACT LATIN [FMA:62996, FMA:TA] +synonym: "tunica mucosa oesophageae" EXACT OMO:0003011 [FMA:62996, FMA:TA] synonym: "tunica mucosa oesophagi" EXACT [] synonym: "tunica mucosa oesophagi" RELATED [BTO:0002859] xref: BTO:0002859 xref: EMAPA:26981 xref: FMA:62996 xref: MA:0002680 -xref: MESH:D000071041 +xref: MESH:D000071041 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: NCIT:C32538 xref: SCTID:362127004 xref: UMLS:C0227176 {source="ncithesaurus:Esophageal_Mucosa"} @@ -195294,8 +195599,8 @@ def: "The bone that is situated in the orbit on either side of the presphenoid; subset: pheno_slim subset: vertebrate_core synonym: "ala minor (os sphenoidale)" EXACT [FMA:52869] -synonym: "ala minor ossis sphenoidalis" EXACT LATIN [FMA:52869, FMA:TA] -synonym: "alae parvae" RELATED LATIN [Wikipedia:Lesser_wing_of_sphenoid_bone] +synonym: "ala minor ossis sphenoidalis" EXACT OMO:0003011 [FMA:52869, FMA:TA] +synonym: "alae parvae" RELATED OMO:0003011 [Wikipedia:Lesser_wing_of_sphenoid_bone] synonym: "ingrassia's process" EXACT [FMA:52869] synonym: "lesser wing of sphenoid" EXACT [FMA:52869] synonym: "lesser wing of sphenoid bone" RELATED [MA:0002773] @@ -195340,16 +195645,16 @@ id: UBERON:0002479 name: dorsal lateral geniculate nucleus namespace: uberon def: "The main division of the lateral geniculate body; consists of two magnocellular layers [TA] (strata magnocellularia [TA]) and four parvocellular layers [TA] (strata parvocellularia [TA]) and serves as a processing station in the major pathway from the retina to the cerebral cortex, receiving fibers from the optic tract and giving rise to the geniculocalcarine radiation to the visual cortex in the occipital lobe." [http://www.medilexicon.com/medicaldictionary.php?t=61422] -synonym: "corpus geniculatum laterale (Hassler)" RELATED LATIN [NeuroNames:353] +synonym: "corpus geniculatum laterale (Hassler)" RELATED OMO:0003011 [NeuroNames:353] synonym: "DLG" BROAD OMO:0003000 [BIRNLEX:1595, NIFSTD:NeuroNames_abbrevSource] synonym: "dorsal nucleus of lateral geniculate body" RELATED [MA:0002775] synonym: "dorsal part of the lateral geniculate complex" RELATED [NeuroNames:353] synonym: "lateral geniculate complex, dorsal part" EXACT [] synonym: "lateral geniculate nucleus dorsal part" RELATED [BAMS:LGd] synonym: "lateral geniculate nucleus, dorsal part" EXACT [NeuroNames:353] -synonym: "nucleus corporis geniculati lateralis, pars dorsalis" RELATED LATIN [NeuroNames:353] -synonym: "nucleus dorsalis corporis geniculati lateralis" EXACT LATIN [FMA:62214, FMA:TA] -synonym: "nucleus geniculatus lateralis dorsalis" RELATED LATIN [NeuroNames:353] +synonym: "nucleus corporis geniculati lateralis, pars dorsalis" RELATED OMO:0003011 [NeuroNames:353] +synonym: "nucleus dorsalis corporis geniculati lateralis" EXACT OMO:0003011 [FMA:62214, FMA:TA] +synonym: "nucleus geniculatus lateralis dorsalis" RELATED OMO:0003011 [NeuroNames:353] synonym: "nucleus geniculatus lateralis pars dorsalis" EXACT [BIRNLEX:1595] xref: BAMS:DLG xref: BAMS:LGd @@ -195473,8 +195778,8 @@ synonym: "frontal suture of skull" EXACT [] synonym: "median frontal suture" EXACT [] synonym: "metopic suture" RELATED [MA:0002796] synonym: "sutura frontalis" EXACT [Wikipedia:Frontal_suture] -synonym: "sutura frontalis" RELATED LATIN [Wikipedia:Frontal_suture] -synonym: "sutura metopica" EXACT LATIN [FMA:52989, FMA:TA] +synonym: "sutura frontalis" RELATED OMO:0003011 [Wikipedia:Frontal_suture] +synonym: "sutura metopica" EXACT OMO:0003011 [FMA:52989, FMA:TA] xref: EMAPA:19226 xref: EMAPA:35358 xref: FMA:52989 @@ -195555,9 +195860,9 @@ synonym: "deltoid process" RELATED [MP:0004353] synonym: "deltoid tuberosity" EXACT [FMA:23418] synonym: "deltoid tuberosity of humerus" EXACT [FMA:23418] synonym: "pectoral process" RELATED [] -synonym: "tuberositas deltoidea" EXACT LATIN [FMA:23418, FMA:TA] +synonym: "tuberositas deltoidea" EXACT OMO:0003011 [FMA:23418, FMA:TA] synonym: "tuberositas deltoidea (corpus humeri)" EXACT [] -synonym: "tuberositas deltoidea humeri" EXACT LATIN [Wikipedia:Deltoid_tuberosity] +synonym: "tuberositas deltoidea humeri" EXACT OMO:0003011 [Wikipedia:Deltoid_tuberosity] xref: AAO:0000736 xref: EMAPA:25052 xref: FMA:23418 @@ -195600,7 +195905,7 @@ subset: pheno_slim synonym: "epithelial tissue of iris" EXACT [OBOL:automatic] synonym: "epithelium of iris" EXACT [OBOL:automatic] synonym: "epithelium pigmentosum (iris)" EXACT [FMA:58517] -synonym: "epithelium pigmentosum iridis" EXACT LATIN [FMA:58517, FMA:TA] +synonym: "epithelium pigmentosum iridis" EXACT OMO:0003011 [FMA:58517, FMA:TA] synonym: "iris epithelial tissue" EXACT [OBOL:automatic] synonym: "iris epithelium" EXACT [FMA:58517] synonym: "iris pigmented epithelium" RELATED [MA:0002826] @@ -195643,7 +195948,7 @@ def: "The lymph nodes located in the mesentery, of which there are 3 classes: il subset: human_reference_atlas subset: pheno_slim synonym: "mesenteric node" EXACT [] -synonym: "nodi lymphoidei mesenterici" RELATED LATIN [BTO:0000767] +synonym: "nodi lymphoidei mesenterici" RELATED OMO:0003011 [BTO:0000767] xref: BTO:0000767 xref: EMAPA:35561 xref: FMA:12795 @@ -195666,11 +195971,11 @@ namespace: uberon def: "The supporting bundles of muscular fibers lining the walls of the ventricles of the heart." [MGI:monikat, MP:0004067] subset: pheno_slim synonym: "cardiac trabecula" RELATED [GO:0060347] -synonym: "columnae carneae" RELATED LATIN [Wikipedia:Trabeculae_carneae] +synonym: "columnae carneae" RELATED OMO:0003011 [Wikipedia:Trabeculae_carneae] synonym: "heart trabecula" RELATED [GO:0060347] synonym: "trabecula of heart" RELATED [] synonym: "trabeculae carneae" RELATED OMO:0003004 [] -synonym: "trabeculae carneae cordis" RELATED LATIN [Wikipedia:Trabeculae_carneae] +synonym: "trabeculae carneae cordis" RELATED OMO:0003011 [Wikipedia:Trabeculae_carneae] synonym: "ventricle trabecula carnea" EXACT [MA:0002831] synonym: "ventricular trabecula" RELATED [MA:0002831] xref: EMAPA:18626 @@ -195804,7 +196109,7 @@ subset: pheno_slim subset: uberon_slim synonym: "base of cranium" EXACT [] synonym: "base of skull" EXACT [FMA:52801] -synonym: "basis cranii" EXACT LATIN [FMA:52801, FMA:TA, Wikipedia:Base_of_skull] +synonym: "basis cranii" EXACT OMO:0003011 [FMA:52801, FMA:TA, Wikipedia:Base_of_skull] synonym: "cranial base" EXACT [FMA:52801, MA:0002840] xref: FMA:52801 xref: MA:0002840 @@ -195858,7 +196163,7 @@ def: "Connective tissue composed of elastic fibers." [http://orcid.org/0000-0002 subset: uberon_slim synonym: "elastic connective tissue" EXACT [] synonym: "elastic fiber" NARROW [] -synonym: "textus connectivus elasticus" EXACT LATIN [] +synonym: "textus connectivus elasticus" EXACT OMO:0003011 [] xref: FMA:20113 xref: GAID:926 xref: MA:0002853 @@ -195880,7 +196185,7 @@ namespace: uberon def: "The middle layer of an artery or vein. [WP,unvetted]." [Wikipedia:Tunica_media] comment: May be composed of smooth muscle and elastic tissue subset: uberon_slim -synonym: "tunica media vasorum" RELATED LATIN [BTO:0002011, Wikipedia:Tunica_media] +synonym: "tunica media vasorum" RELATED OMO:0003011 [BTO:0002011, Wikipedia:Tunica_media] xref: BTO:0002011 xref: EMAPA:36298 xref: FMA:55590 @@ -195982,7 +196287,7 @@ subset: efo_slim subset: pheno_slim subset: uberon_slim synonym: "Druese" RELATED [BTO:0000522] -synonym: "glandula" RELATED LATIN [BTO:0000522, Wikipedia:Gland] +synonym: "glandula" RELATED OMO:0003011 [BTO:0000522, Wikipedia:Gland] synonym: "glandular organ" EXACT [http://orcid.org/0000-0002-6601-2165] xref: AAO:0000212 xref: AEO:0000096 @@ -195993,7 +196298,7 @@ xref: EHDAA:2161 xref: EHDAA:4475 xref: EHDAA:6522 xref: EMAPA:18425 -xref: FBbt:00100317 +xref: FBbt:00100317 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:7146 xref: FMA:86294 xref: galen:Gland @@ -196026,7 +196331,7 @@ subset: vertebrate_core synonym: "blastocyst" RELATED [] synonym: "ectoblast" RELATED [MP:0003886] synonym: "epiblast" EXACT [VHOG:0000243] -synonym: "epiblastus" RELATED LATIN [Wikipedia:Epiblast] +synonym: "epiblastus" RELATED OMO:0003011 [Wikipedia:Epiblast] synonym: "primitive ectoderm" RELATED [VHOG:0000243] xref: BTO:0004593 xref: FMA:296704 @@ -196081,7 +196386,7 @@ subset: uberon_slim synonym: "sensillum" EXACT [FBbt:00007152, HAO:0000933] xref: BTO:0001237 xref: EFO:0000939 -xref: FBbt:00007152 +xref: FBbt:00007152 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: HAO:0000933 xref: MAT:0000163 xref: MIAA:0000163 @@ -196125,7 +196430,7 @@ subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "arcus pharyngei" RELATED LATIN [Wikipedia:Pharyngeal_arch] +synonym: "arcus pharyngei" RELATED OMO:0003011 [Wikipedia:Pharyngeal_arch] synonym: "branchial arch" NARROW [BTO:0001785, MP:0002884] synonym: "pharyngeal arches" EXACT OMO:0003004 [] synonym: "visceral arch" RELATED [] @@ -196174,7 +196479,7 @@ xref: AAO:0000269 xref: AAO:0000975 xref: EFO:0000941 xref: MAT:0000249 -xref: MESH:D053403 +xref: MESH:D053403 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: MIAA:0000249 xref: TAO:0000034 xref: VHOG:0001243 @@ -196277,9 +196582,9 @@ synonym: "wriggler" NARROW [Wikipedia:Larva] synonym: "zoea" NARROW [Wikipedia:Larva] xref: AEO:0000126 xref: BTO:0000707 -xref: FBbt:00001727 +xref: FBbt:00001727 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: HAO:0000459 -xref: MESH:D007814 +xref: MESH:D007814 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: TAO:0002048 xref: Wikipedia:Larva is_a: UBERON:0000468 ! multicellular organism @@ -196335,13 +196640,13 @@ name: intermediate hypothalamic region namespace: uberon def: "The portion of the hypothalamus located generally internal to the region of the infundibulum." [http://medical-dictionary.thefreedictionary.com] comment: ) -synonym: "area hypothalamica intermedia" EXACT LATIN [FMA:62028, FMA:TA] +synonym: "area hypothalamica intermedia" EXACT OMO:0003011 [FMA:62028, FMA:TA] synonym: "IHR" BROAD OMO:0003000 [BIRNLEX:1015, NIFSTD:NeuroNames_abbrevSource] synonym: "intermediate hypothalamic area" EXACT [FMA:62028] synonym: "intermediate hypothalamus" RELATED [TAO:0006000] synonym: "medial hypothalamus" RELATED [MESH:A08.186.211.730.385.357.352] synonym: "middle hypothalamus" RELATED [MESH:A08.186.211.730.385.357.352] -synonym: "regio hypothalamica intermedia" RELATED LATIN [NeuroNames:392] +synonym: "regio hypothalamica intermedia" RELATED OMO:0003011 [NeuroNames:392] xref: BAMS:IHR xref: BIRNLEX:1015 xref: FMA:62028 @@ -196397,9 +196702,9 @@ synonym: "fornicate convolution" RELATED [NeuroNames:834] synonym: "fornicate gyrus" EXACT [FMA:72719] synonym: "fornicate lobe" RELATED [NeuroNames:834] synonym: "grande lobe limbique of Broca" EXACT [] -synonym: "gyrus fornicatus" RELATED LATIN [NeuroNames:834] +synonym: "gyrus fornicatus" RELATED OMO:0003011 [NeuroNames:834] synonym: "limbic lobe (carpenter)" EXACT [] -synonym: "lobus limbicus" RELATED LATIN [Wikipedia:Limbic_lobe] +synonym: "lobus limbicus" RELATED OMO:0003011 [Wikipedia:Limbic_lobe] xref: BAMS:Limbic_lobe xref: BAMS:LL xref: BIRNLEX:1128 @@ -196407,7 +196712,7 @@ xref: CALOHA:TS-2061 xref: DHBA:12155 xref: FMA:72719 xref: HBA:4219 -xref: MESH:D065726 +xref: MESH:D065726 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: neuronames:834 {source="BIRNLEX:1128"} xref: SCTID:279215006 xref: UMLS:C0458337 {source="BIRNLEX:1128"} @@ -196423,7 +196728,7 @@ namespace: uberon def: "The cochlear nuclei consist of: (a) the dorsal cochlear nucleus, corresponding to the tuberculum acusticum on the dorso-lateral surface of the inferior peduncle; and (b) the ventral or accessory cochlear nucleus, placed between the two divisions of the nerve, on the ventral aspect of the inferior peduncle. [WP,unvetted]." [Wikipedia:Cochlear_nuclei] subset: uberon_slim synonym: "cochlear nuclei" EXACT [FMA:72240] -synonym: "nuclei cochleares" RELATED LATIN [Wikipedia:Cochlear_nuclei] +synonym: "nuclei cochleares" RELATED OMO:0003011 [Wikipedia:Cochlear_nuclei] xref: BAMS:CN xref: BIRNLEX:1151 xref: BM:Me-Co @@ -196478,10 +196783,10 @@ name: preoptic periventricular nucleus namespace: uberon def: "The preoptic periventricular nucleus is located along the midline and is medial to the medial preoptic nucleus.[WP,unvetted]." [Wikipedia:Preoptic_area#Preoptic_periventricular_nucleus] synonym: "dorsal periventricular hypothalamic nucleus" RELATED [NeuroNames:379] -synonym: "nucleus periventricularis hypothalami, pars dorsalis" RELATED LATIN [NeuroNames:379] -synonym: "nucleus periventricularis praeopticus" RELATED LATIN [NeuroNames:379] -synonym: "nucleus periventricularis preopticus" RELATED LATIN [NeuroNames:379] -synonym: "nucleus preopticus periventricularis" EXACT LATIN [FMA:62324, FMA:TA] +synonym: "nucleus periventricularis hypothalami, pars dorsalis" RELATED OMO:0003011 [NeuroNames:379] +synonym: "nucleus periventricularis praeopticus" RELATED OMO:0003011 [NeuroNames:379] +synonym: "nucleus periventricularis preopticus" RELATED OMO:0003011 [NeuroNames:379] +synonym: "nucleus preopticus periventricularis" EXACT OMO:0003011 [FMA:62324, FMA:TA] synonym: "periventricular hypothalamic nucleus, preoptic part" RELATED [BAMS:PVpo] synonym: "periventricular nucleus, anterior portion" RELATED [NeuroNames:379] synonym: "periventricular preoptic nucleus" EXACT [FMA:62324] @@ -196509,14 +196814,14 @@ def: "The median preoptic nucleus is located along the midline in a position sig subset: uberon_slim synonym: "median preoptic nucleus (Loo)" RELATED [NeuroNames:378] synonym: "MnPO" BROAD OMO:0003000 [BIRNLEX:1208, NIFSTD:NeuroNames_abbrevSource] -synonym: "nucleus praeopticus medianus" RELATED LATIN [NeuroNames:378] -synonym: "nucleus preopticus medianus" RELATED LATIN [NeuroNames:378] +synonym: "nucleus praeopticus medianus" RELATED OMO:0003011 [NeuroNames:378] +synonym: "nucleus preopticus medianus" RELATED OMO:0003011 [NeuroNames:378] synonym: "periventricular nucleus, preventricular portion" RELATED [NeuroNames:378] xref: BAMS:MEPO xref: BAMS:MnPO xref: BIRNLEX:1208 xref: BM:MPO -xref: BTO:0006168 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: BTO:0006168 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: DHBA:13063 xref: FMA:62323 xref: HBA:4548 @@ -196541,7 +196846,7 @@ name: septal nuclear complex namespace: uberon def: "Collection of nerve cells in the medial forebrain lying generally in front of the anterior commissure (Maryann Martone)." [BIRNLEX:1313] subset: uberon_slim -synonym: "nuclei septales" RELATED LATIN [Wikipedia:Septal_nuclei] +synonym: "nuclei septales" RELATED OMO:0003011 [Wikipedia:Septal_nuclei] synonym: "parolfactory nuclei" EXACT [FMA:61845] synonym: "septal nuclei" EXACT [FMA:61845] synonym: "septal nucleus" EXACT [MA:0002978] @@ -196575,7 +196880,7 @@ namespace: uberon synonym: "anterior ventral periventricular nucleus of hypothalamus" RELATED [BAMS:AVPe] synonym: "anteroventral periventricular nucleus of the hypothalamus" RELATED [BAMS:AVPV] synonym: "AVPe" BROAD OMO:0003000 [BIRNLEX:1401, NIFSTD:NeuroNames_abbrevSource] -synonym: "nucleus periventricularis anteroventralis" RELATED LATIN [NeuroNames:382] +synonym: "nucleus periventricularis anteroventralis" RELATED OMO:0003011 [NeuroNames:382] synonym: "ventral periventricular hypothalamic nucleus" RELATED [NeuroNames:382] xref: BAMS:AVPe xref: BAMS:AVPV @@ -196602,7 +196907,7 @@ name: metathalamus namespace: uberon def: "The metathalamus is a composite structure of the thalamus, consisting of the medial geniculate nucleus and the lateral geniculate nucleus. [WP,unvetted]." [Wikipedia:Metathalamus] subset: uberon_slim -synonym: "corpora geniculata" RELATED LATIN [Wikipedia:Metathalamus] +synonym: "corpora geniculata" RELATED OMO:0003011 [Wikipedia:Metathalamus] synonym: "geniculate group of dorsal thalamus" RELATED [BAMS:GENd] synonym: "geniculate group of the dorsal thalamus" EXACT [FMA:62023] synonym: "geniculate thalamic group" EXACT [MA:0000868] @@ -196619,6 +196924,7 @@ xref: EV:0100217 xref: FMA:62023 xref: MA:0000868 xref: MBA:1008 +xref: MESH:D005829 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} xref: neuronames:351 {source="BIRNLEX:1461"} xref: SCTID:361550004 xref: Wikipedia:Metathalamus @@ -196638,19 +196944,19 @@ subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "corticospinal fibers" EXACT [NeuroNames:1320] -synonym: "fasciculus cerebro-spinalis" EXACT LATIN [NeuroNames:1320] -synonym: "fasciculus pyramidalis" EXACT LATIN [NeuroNames:800] -synonym: "fibrae corticospinales" EXACT LATIN [NeuroNames:1320] +synonym: "fasciculus cerebro-spinalis" EXACT OMO:0003011 [NeuroNames:1320] +synonym: "fasciculus pyramidalis" EXACT OMO:0003011 [NeuroNames:800] +synonym: "fibrae corticospinales" EXACT OMO:0003011 [NeuroNames:1320] synonym: "pyramid (Willis)" EXACT [NeuroNames:800] synonym: "pyramidal tract" BROAD INCONSISTENT [BIRNLEX:1464, MP:0002878, neuronames:1320] -synonym: "tractus cortico-spinalis" EXACT LATIN [NeuroNames:1320] -synonym: "tractus corticospinalis" EXACT LATIN [NeuroNames:1320, Wikipedia:Corticospinal_tract] -synonym: "tractus pyramidalis" EXACT LATIN [NeuroNames:800] +synonym: "tractus cortico-spinalis" EXACT OMO:0003011 [NeuroNames:1320] +synonym: "tractus corticospinalis" EXACT OMO:0003011 [NeuroNames:1320, Wikipedia:Corticospinal_tract] +synonym: "tractus pyramidalis" EXACT OMO:0003011 [NeuroNames:800] xref: BAMS:P xref: BIRNLEX:1464 xref: BM:CST xref: BM:Me-PyT -xref: BTO:0006132 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: BTO:0006132 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: DHBA:12776 xref: DMBA:17756 xref: EMAPA:36600 @@ -196680,11 +196986,12 @@ subset: human_reference_atlas synonym: "cervical segment of spinal cord" EXACT [FMA:71166] synonym: "cervical segments of spinal cord [1-8]" EXACT [FMA:71166] synonym: "cervical spinal cord" EXACT [FMA:71166] -synonym: "pars cervicalis medullae spinalis" EXACT LATIN [FMA:71166, FMA:TA] -synonym: "segmenta cervicalia medullae spinalis [1-8" EXACT LATIN [FMA:71166, FMA:TA] +synonym: "pars cervicalis medullae spinalis" EXACT OMO:0003011 [FMA:71166, FMA:TA] +synonym: "segmenta cervicalia medullae spinalis [1-8" EXACT OMO:0003011 [FMA:71166, FMA:TA] xref: BIRNLEX:1499 xref: FMA:71166 xref: MA:0003081 +xref: MESH:D066193 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} xref: NCIT:C12892 xref: neuronames:1654 xref: SCTID:180960003 @@ -196703,7 +197010,7 @@ name: vestibulocochlear nerve root namespace: uberon def: "Either of the two roots that come of the vestibulocochlear nerve." [http://orcid.org/0000-0002-6601-2165] synonym: "central part of vestibulocochlear nerve" EXACT [FMA:72499] -synonym: "fibrae nervi statoacustici" EXACT LATIN [FMA:72499, FMA:TA] +synonym: "fibrae nervi statoacustici" EXACT OMO:0003011 [FMA:72499, FMA:TA] synonym: "root of vestibulocochlear nerve" EXACT [DHBA:12868] synonym: "statoacoustic nerve fibers" EXACT [FMA:72499] synonym: "vestibulocochlear nerve fibers" EXACT [FMA:72499] @@ -196730,7 +197037,7 @@ def: "A region of the brain consisting of ventral and rostral subcortical region subset: human_reference_atlas subset: uberon_slim synonym: "basal forebrain area" RELATED [NeuroNames:1997] -synonym: "pars basalis telencephali" RELATED LATIN [Wikipedia:Basal_forebrain] +synonym: "pars basalis telencephali" RELATED OMO:0003011 [Wikipedia:Basal_forebrain] xref: BAMS:Basal_forebrain xref: BIRNLEX:1560 xref: BM:Tel-BF @@ -196739,7 +197046,7 @@ xref: DHBA:10349 xref: EMAPA:35164 xref: FMA:77700 xref: HBA:4300 -xref: MESH:D066187 +xref: MESH:D066187 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: neuronames:1997 {source="BIRNLEX:1560"} xref: PBA:128012976 xref: Wikipedia:Basal_forebrain @@ -196768,12 +197075,12 @@ id: UBERON:0002770 name: posterior hypothalamic region namespace: uberon def: "The part of the hypothalamus posterior to the middle region consisting of several nuclei including the medial mamillary nucleus, lateral mamillary nucleus, and posterior hypothalamic nucleus (posterior hypothalamic area). The posterior hypothalamic area is concerned with control of sympathetic responses and is sensitive to conditions of decreasing temperature and controls the mechanisms for the conservation and increased production of heat." [MESH:A08.186.211.730.385.357.362] -synonym: "hypothalamus posterior" RELATED LATIN [NeuroNames:411] +synonym: "hypothalamus posterior" RELATED OMO:0003011 [NeuroNames:411] synonym: "mammillary level of hypothalamus" EXACT [FMA:62029] synonym: "mammillary region" EXACT [FMA:62029] synonym: "PHR" BROAD OMO:0003000 [BIRNLEX:1651, NIFSTD:NeuroNames_abbrevSource] synonym: "posterior hypothalamus" EXACT [FMA:62029] -synonym: "regio hypothalamica posterior" RELATED LATIN [NeuroNames:411] +synonym: "regio hypothalamica posterior" RELATED OMO:0003011 [NeuroNames:411] xref: BAMS:PH xref: BAMS:PHR xref: BIRNLEX:1651 @@ -196954,8 +197261,8 @@ synonym: "auditory ganglion" EXACT [ZFA:0000588] synonym: "auditory ganglion" RELATED [BIRNLEX:2564] synonym: "ganglion VIII" EXACT [] synonym: "gVIII" EXACT [ZFA:0000588] -synonym: "nucleus nervi oculomotorii ventrolateralis" RELATED LATIN [NeuroNames:496] -synonym: "nucleus nervi oculomotorii, pars ventralis" RELATED LATIN [NeuroNames:496] +synonym: "nucleus nervi oculomotorii ventrolateralis" RELATED OMO:0003011 [NeuroNames:496] +synonym: "nucleus nervi oculomotorii, pars ventralis" RELATED OMO:0003011 [NeuroNames:496] synonym: "SAG" BROAD [ZFA:0000588] synonym: "statoacoustic (VIII) ganglion" EXACT [ZFA:0000588] synonym: "statoacoustic ganglia" EXACT [ZFA:0000588] @@ -196996,9 +197303,9 @@ subset: uberon_slim synonym: "accessory cochlear nucleus" RELATED [NeuroNames:722] synonym: "anterior cochlear nucleus" EXACT [FMA:54621] synonym: "c1281209" EXACT [BIRNLEX:2567] -synonym: "nucleus acustici accessorici" RELATED LATIN [NeuroNames:722] -synonym: "nucleus cochlearis anterior" RELATED LATIN [NeuroNames:722] -synonym: "nucleus cochlearis ventralis" RELATED LATIN [NeuroNames:722] +synonym: "nucleus acustici accessorici" RELATED OMO:0003011 [NeuroNames:722] +synonym: "nucleus cochlearis anterior" RELATED OMO:0003011 [NeuroNames:722] +synonym: "nucleus cochlearis ventralis" RELATED OMO:0003011 [NeuroNames:722] synonym: "VCo" BROAD OMO:0003000 [BIRNLEX:2567, NIFSTD:NeuroNames_abbrevSource] synonym: "ventral cochlear nuclei" RELATED [NeuroNames:722] synonym: "ventral cochlear nucleus" EXACT [FMA:54621] @@ -197030,8 +197337,8 @@ synonym: "DCo" BROAD OMO:0003000 [BIRNLEX:2569, NIFSTD:NeuroNames_abbrevSource] synonym: "dorsal cochlear nucleus" EXACT [FMA:54624] synonym: "dorsal coclear nucleus" RELATED [BAMS:DCO] synonym: "dorsal division of cochlear nucleus" EXACT [FMA:54624] -synonym: "nucleus cochlearis dorsalis" RELATED LATIN [NeuroNames:721] -synonym: "nucleus cochlearis posterior" RELATED LATIN [Wikipedia:Dorsal_cochlear_nucleus] +synonym: "nucleus cochlearis dorsalis" RELATED OMO:0003011 [NeuroNames:721] +synonym: "nucleus cochlearis posterior" RELATED OMO:0003011 [Wikipedia:Dorsal_cochlear_nucleus] synonym: "posterior cochlear nucleus" EXACT [FMA:54624] synonym: "tuberculum acousticum" EXACT [] xref: BAMS:DC @@ -197062,7 +197369,7 @@ synonym: "anterior part of the ventral cochlear nucleus" RELATED [NeuroNames:723 synonym: "anterior ventral cochlear nucleus" RELATED [NeuroNames:723] synonym: "anteroventral auditory nucleus" EXACT [FMA:72571] synonym: "AVCo" BROAD OMO:0003000 [BIRNLEX:2572, NIFSTD:NeuroNames_abbrevSource] -synonym: "nucleus cochlearis anteroventralis" RELATED LATIN [NeuroNames:723] +synonym: "nucleus cochlearis anteroventralis" RELATED OMO:0003011 [NeuroNames:723] synonym: "nucleus magnocellularis" EXACT [BIRNLEX:2572] synonym: "ventral cochlear nucleus, anterior part" RELATED [NeuroNames:723] synonym: "ventral coclear nucleus anterior part" RELATED [NeuroNames:723] @@ -197081,7 +197388,7 @@ relationship: part_of UBERON:0002828 {source="NIFSTD"} ! ventral cochlear nucleu id: UBERON:0002831 name: posteroventral cochlear nucleus namespace: uberon -synonym: "nucleus cochlearis posteroventralis" RELATED LATIN [NeuroNames:724] +synonym: "nucleus cochlearis posteroventralis" RELATED OMO:0003011 [NeuroNames:724] synonym: "posterior part of anterior cochlear nucleus" EXACT [BIRNLEX:2573] synonym: "posterior part of the ventral cochlear nucleus" RELATED [NeuroNames:724] synonym: "posterior ventral cochlear nucleus" RELATED [NeuroNames:724] @@ -197150,9 +197457,9 @@ subset: uberon_slim synonym: "hypoglossal nerve nucleus" EXACT [FMA:54505] synonym: "hypoglossal nucleus" EXACT [FMA:54505] synonym: "hypoglossal XII nucleus" EXACT [MA:0001039] -synonym: "nucleus hypoglossalis" RELATED LATIN [NeuroNames:757] -synonym: "nucleus nervi hypoglossi" EXACT LATIN [FMA:54505, FMA:TA] -synonym: "nucleus nervi hypoglossi" RELATED LATIN [Wikipedia:Hypoglossal_nucleus] +synonym: "nucleus hypoglossalis" RELATED OMO:0003011 [NeuroNames:757] +synonym: "nucleus nervi hypoglossi" EXACT OMO:0003011 [FMA:54505, FMA:TA] +synonym: "nucleus nervi hypoglossi" RELATED OMO:0003011 [Wikipedia:Hypoglossal_nucleus] synonym: "nucleus of hypoglossal nerve" EXACT [FMA:54505] synonym: "twelfth cranial nerve nucleus" EXACT [FMA:54505] xref: BAMS:12 @@ -197201,8 +197508,8 @@ synonym: "NLOT" EXACT OMO:0003000 [] synonym: "nucleus of the lateral olfactory tract" RELATED [NeuroNames:242] synonym: "nucleus of the lateral olfactory tract (ganser)" EXACT [BIRNLEX:2702] synonym: "nucleus of the olfactory tract" RELATED [BAMS:LOT] -synonym: "nucleus of tractus olfactorius lateralis" RELATED LATIN [NeuroNames:242] -synonym: "nucleus striae olfactoriae lateralis" RELATED LATIN [NeuroNames:242] +synonym: "nucleus of tractus olfactorius lateralis" RELATED OMO:0003011 [NeuroNames:242] +synonym: "nucleus striae olfactoriae lateralis" RELATED OMO:0003011 [NeuroNames:242] xref: BAMS:LOT xref: BAMS:NLOT xref: BIRNLEX:2702 @@ -197273,7 +197580,7 @@ synonym: "fissure of Rolando" EXACT [] synonym: "rolandic fissure" EXACT [BIRNLEX:4035] synonym: "sulcus centralis" EXACT [BIRNLEX:4035] synonym: "sulcus centralis (rolandi)" EXACT [BIRNLEX:4035] -synonym: "sulcus centralis cerebri" EXACT LATIN [BIRNLEX:4035, Wikipedia:Central_sulcus] +synonym: "sulcus centralis cerebri" EXACT OMO:0003011 [BIRNLEX:4035, Wikipedia:Central_sulcus] synonym: "sulcus of Rolando" EXACT [] xref: BAMS:cs xref: BIRNLEX:4035 @@ -197384,7 +197691,7 @@ id: UBERON:0002928 name: dentate gyrus polymorphic layer namespace: uberon def: "A cellular layer of the dentate gyrus enclosed by the granule cell layer. A number of cell types are located in the polymorphic layer but the most prominent is the mossy cell." [http://orcid.org/0000-0002-6601-2165, PMCID:PMC2492885] -synonym: "CA4" RELATED DUBIOUS [PMID:17765709] +synonym: "CA4" RELATED OMO:0003002 [PMID:17765709] synonym: "polymorph layer of the dentate gyrus" RELATED [BAMS:PoDG] xref: BAMS:po xref: BAMS:PoDG @@ -197415,7 +197722,7 @@ synonym: "cerebellum granule layer" EXACT [] synonym: "granular layer of cerebellum" RELATED [BTO:0004425] synonym: "granule cell layer of cerebellar cortex" EXACT [BIRNLEX:779] synonym: "stratum granulosum cerebelli" EXACT [BTO:0004425] -synonym: "stratum granulosum corticis cerebelli" EXACT LATIN [FMA:83140, FMA:TA] +synonym: "stratum granulosum corticis cerebelli" EXACT OMO:0003011 [FMA:83140, FMA:TA] xref: BIRNLEX:779 xref: BTO:0004425 xref: CALOHA:TS-1247 @@ -197444,8 +197751,8 @@ subset: pheno_slim synonym: "cerebellar molecular layer" EXACT [GO:0021679] synonym: "cerebellum molecular cell layer" EXACT [] synonym: "cerebellum molecular layer" EXACT [] -synonym: "fasciculi thalami" RELATED LATIN [NeuroNames:366] -synonym: "stratum moleculare corticis cerebelli" EXACT LATIN [FMA:83897, FMA:TA] +synonym: "fasciculi thalami" RELATED OMO:0003011 [NeuroNames:366] +synonym: "stratum moleculare corticis cerebelli" EXACT OMO:0003011 [FMA:83897, FMA:TA] synonym: "thalamic fiber tracts" RELATED [NeuroNames:366] xref: BAMS:thf xref: BIRNLEX:810 @@ -197478,13 +197785,13 @@ subset: pheno_slim synonym: "cerebellar Purkinje cell layer" EXACT [FMA:83896, GO:0021694] synonym: "cerebellum Purkinje cell layer" EXACT [] synonym: "cerebellum Purkinje layer" EXACT [] -synonym: "nuclei reticulares (thalami)" RELATED LATIN [NeuroNames:365] -synonym: "nucleus reticularis" RELATED LATIN [NeuroNames:365] -synonym: "nucleus reticulatus (thalami)" RELATED LATIN [NeuroNames:365] -synonym: "nucleus thalamicus reticularis" RELATED LATIN [NeuroNames:365] +synonym: "nuclei reticulares (thalami)" RELATED OMO:0003011 [NeuroNames:365] +synonym: "nucleus reticularis" RELATED OMO:0003011 [NeuroNames:365] +synonym: "nucleus reticulatus (thalami)" RELATED OMO:0003011 [NeuroNames:365] +synonym: "nucleus thalamicus reticularis" RELATED OMO:0003011 [NeuroNames:365] synonym: "Purkinje cell layer" EXACT [FMA:83896] synonym: "reticular nucleus thalamus (Arnold)" RELATED [NeuroNames:365] -synonym: "reticulatum thalami (Hassler)" RELATED LATIN [NeuroNames:365] +synonym: "reticulatum thalami (Hassler)" RELATED OMO:0003011 [NeuroNames:365] xref: BIRNLEX:818 xref: BTO:0004909 xref: EMAPA:35223 @@ -197515,18 +197822,18 @@ subset: human_reference_atlas subset: uberon_slim synonym: "dorsal pons" EXACT [] synonym: "dorsal portion of pons" EXACT [FMA:71108] -synonym: "pars dorsalis pontis" RELATED LATIN [NeuroNames:557] -synonym: "pars posterior pontis" RELATED LATIN [NeuroNames:557] +synonym: "pars dorsalis pontis" RELATED OMO:0003011 [NeuroNames:557] +synonym: "pars posterior pontis" RELATED OMO:0003011 [NeuroNames:557] synonym: "tegmental portion of pons" EXACT [FMA:71108] synonym: "tegmentum of pons" EXACT [FMA:71108] -synonym: "tegmentum pontis" EXACT LATIN [FMA:71108, FMA:TA] -synonym: "tegmentum pontis" RELATED LATIN [Wikipedia:Pontine_tegmentum] +synonym: "tegmentum pontis" EXACT OMO:0003011 [FMA:71108, FMA:TA] +synonym: "tegmentum pontis" RELATED OMO:0003011 [Wikipedia:Pontine_tegmentum] xref: BAMS:PTg xref: BIRNLEX:923 xref: DHBA:12416 xref: FMA:71108 xref: HBA:9135 -xref: MESH:D065821 +xref: MESH:D065821 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: neuronames:557 {source="BIRNLEX:923"} xref: SCTID:362401009 xref: UMLS:C0228426 {source="BIRNLEX:923"} @@ -197565,8 +197872,8 @@ namespace: uberon def: "The thoracic nerves are the spinal nerves emerging from the thoracic vertebrae. [WP,unvetted]." [Wikipedia:Thoracic_spinal_cord] subset: human_reference_atlas subset: uberon_slim -synonym: "pars thoracica medullae spinalis" EXACT LATIN [FMA:71167, FMA:TA] -synonym: "segmenta thoracica medullae spinalis [1-12]" EXACT LATIN [FMA:71167, FMA:TA] +synonym: "pars thoracica medullae spinalis" EXACT OMO:0003011 [FMA:71167, FMA:TA] +synonym: "segmenta thoracica medullae spinalis [1-12]" EXACT OMO:0003011 [FMA:71167, FMA:TA] synonym: "thoracic region of spinal cord" EXACT [FMA:71167] synonym: "thoracic segment of spinal cord" EXACT [FMA:71167] synonym: "thoracic segments of spinal cord [1-12]" EXACT [FMA:71167] @@ -197592,7 +197899,7 @@ name: trigeminal nerve fibers namespace: uberon def: "A nerve fiber that is part of a trigeminal nerve." [OBOL:automatic] synonym: "central part of trigeminal nerve" EXACT [FMA:72501] -synonym: "fibrae nervi trigemini" RELATED LATIN [NeuroNames:607] +synonym: "fibrae nervi trigemini" RELATED OMO:0003011 [NeuroNames:607] synonym: "trigeminal nerve fibers" EXACT [FMA:72501] synonym: "trigeminal nerve tract" EXACT [FMA:72501] xref: BAMS:5nf @@ -197618,10 +197925,10 @@ subset: vertebrate_core synonym: "nasal I placode" RELATED [] synonym: "nasal placode" RELATED [] synonym: "olfactory placodes" EXACT OMO:0003004 [] -synonym: "placoda nasalis" EXACT LATIN [] -synonym: "placoda olfactoria" EXACT LATIN [] +synonym: "placoda nasalis" EXACT OMO:0003011 [] +synonym: "placoda olfactoria" EXACT OMO:0003011 [] xref: AAO:0011076 -xref: BTO:0006222 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: BTO:0006222 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: EFO:0003420 xref: EHDAA2:0001232 xref: EHDAA:1504 @@ -197730,7 +198037,7 @@ synonym: "epitrichium" RELATED [MP:0013530] synonym: "EVL" RELATED [ZFA:0001185] synonym: "periderm" RELATED [] synonym: "skin periderm" EXACT [EHDAA2:0001846] -xref: BTO:0003377 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: BTO:0003377 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: EHDAA2:0001846 xref: EHDAA:6538 xref: FMA:295662 @@ -197820,10 +198127,10 @@ def: "In mammals, the pronephric duct is the predecessor of the Wolffian duct[WP comment: The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the pronephric kidney[GOC:mtg_kidney_jan10, PMID:15647339, XAO:0000063, ZFA:0000150] subset: uberon_slim synonym: "archinephric duct" RELATED [VHOG:0000082] -synonym: "ductus pronephricus" RELATED LATIN [Wikipedia:Pronephric_duct] +synonym: "ductus pronephricus" RELATED OMO:0003011 [Wikipedia:Pronephric_duct] synonym: "pronephric ducts" RELATED OMO:0003004 [ZFA:0000150] xref: AAO:0011088 -xref: BTO:0005991 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: BTO:0005991 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: NCIT:C34279 xref: SCTID:361406002 xref: TAO:0000150 @@ -197917,7 +198224,7 @@ synonym: "IM" RELATED [] synonym: "intermediate mesenchyme" RELATED [https://github.com/obophenotype/uberon/wiki/The-neural-crest] synonym: "intermediate plate" RELATED [EMAPA:16178] synonym: "intermediate plate mesoderm" RELATED [https://orcid.org/0000-0002-6601-2165] -synonym: "mesenchyma intermedium" RELATED LATIN [Wikipedia:Intermediate_mesoderm] +synonym: "mesenchyma intermedium" RELATED OMO:0003011 [Wikipedia:Intermediate_mesoderm] xref: AAO:0010575 xref: EMAPA:16056 xref: EMAPA:16178 @@ -197952,7 +198259,7 @@ subset: vertebrate_core synonym: "2nd arch" RELATED [EHDAA2:0000050] synonym: "2nd pharyngeal arch" EXACT [] synonym: "2nd visceral arch" RELATED [VHOG:0000297] -synonym: "arcus pharyngeus secundus" EXACT LATIN [Wikipedia:Second_pharyngeal_arch] +synonym: "arcus pharyngeus secundus" EXACT OMO:0003011 [Wikipedia:Second_pharyngeal_arch] synonym: "branchial arch 2" EXACT SENSU [] synonym: "hyoid arch" EXACT [XAO:0000098] synonym: "hyoid bars" RELATED [] @@ -198032,7 +198339,7 @@ synonym: "ear placode" RELATED [] synonym: "ear/otic placode" RELATED [] synonym: "octaval placode" RELATED [ISBN:0471888893] synonym: "octaval VIII placode" RELATED [ISBN:0471888893] -synonym: "placoda otica" EXACT LATIN [] +synonym: "placoda otica" EXACT OMO:0003011 [] xref: AAO:0011079 xref: EFO:0003429 xref: EHDAA2:0001339 @@ -198149,7 +198456,7 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "lens placodes" RELATED OMO:0003004 [ZFA:0000122] -synonym: "placoda lentis" RELATED LATIN [Wikipedia:Lens_placode] +synonym: "placoda lentis" RELATED OMO:0003011 [Wikipedia:Lens_placode] xref: AAO:0011055 xref: EFO:0003494 xref: EHDAA2:0000982 @@ -198185,12 +198492,12 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "archinephric duct" RELATED [VHOG:0000082, Wikipedia:Wolffian_duct] -synonym: "ductus mesonephricus; ductus Wolffi" RELATED LATIN [Wikipedia:Mesonephric_duct] +synonym: "ductus mesonephricus; ductus Wolffi" RELATED OMO:0003011 [Wikipedia:Mesonephric_duct] synonym: "Leydig's duct" RELATED [Wikipedia:Wolffian_duct] synonym: "renal duct" RELATED [] synonym: "Wolffian duct" EXACT [GOC:yaf, Wikipedia:Wolffian_duct, ZFA:0000546] xref: AAO:0000637 -xref: BTO:0005990 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: BTO:0005990 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: EHDAA2:0001243 xref: EHDAA:1590 xref: EMAPA:16577 @@ -198225,7 +198532,7 @@ def: "A region of embryonic ectodermal cells that lie directly above the notocho subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "lamina neuralis" RELATED LATIN [Wikipedia:Neural_plate] +synonym: "lamina neuralis" RELATED OMO:0003011 [Wikipedia:Neural_plate] synonym: "presumptive central nervous system" RELATED [] xref: AAO:0011072 xref: BTO:0001765 @@ -198235,7 +198542,7 @@ xref: EHDAA:346 xref: EHDAA:902 xref: EMAPA:35593 xref: FMA:293879 -xref: MESH:D054258 +xref: MESH:D054258 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: NCIT:C34225 xref: neuronames:1362 xref: RETIRED_EHDAA2:0001252 @@ -198278,7 +198585,7 @@ def: "The paraxial mesoderm is the mesoderm located bilaterally adjacent to the subset: efo_slim subset: uberon_slim subset: vertebrate_core -synonym: "mesoderma paraxiale" RELATED LATIN [Wikipedia:Paraxial_mesoderm] +synonym: "mesoderma paraxiale" RELATED OMO:0003011 [Wikipedia:Paraxial_mesoderm] synonym: "paraxial mesenchyme" EXACT [https://github.com/obophenotype/uberon/issues/30, https://github.com/obophenotype/uberon/wiki/The-neural-crest, ZFA:0000255] synonym: "somitic mesoderm" EXACT [ISBN:9780878932504] xref: AAO:0010568 @@ -198356,7 +198663,7 @@ synonym: "lateral mesoderm" EXACT [GO:0048368] synonym: "lateral plate" RELATED [] synonym: "lateral plate mesenchyme" RELATED [EHDAA2:0000919] synonym: "LPM" EXACT OMO:0003000 [ZFA:0000121] -synonym: "mesoderma laminae lateralis" RELATED LATIN [Wikipedia:Lateral_plate_mesoderm] +synonym: "mesoderma laminae lateralis" RELATED OMO:0003011 [Wikipedia:Lateral_plate_mesoderm] xref: AAO:0010574 xref: EHDAA2:0000919 xref: EHDAA:379 @@ -198396,7 +198703,7 @@ synonym: "myomere" RELATED [] synonym: "myomeres" EXACT OMO:0003004 [TAO:0001056] synonym: "myotome region" RELATED [] synonym: "myotomes" RELATED [] -synonym: "myotomus" RELATED LATIN [Wikipedia:Myotome] +synonym: "myotomus" RELATED OMO:0003011 [Wikipedia:Myotome] xref: AAO:0011067 xref: AEO:0001018 xref: BTO:0000742 @@ -198505,10 +198812,10 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "sclerotomes" EXACT OMO:0003004 [TAO:0001080] -synonym: "sclerotomus" RELATED LATIN [Wikipedia:Sclerotome] +synonym: "sclerotomus" RELATED OMO:0003011 [Wikipedia:Sclerotome] xref: AAO:0010571 xref: AEO:0000212 -xref: BTO:0006255 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: BTO:0006255 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: EHDAA2:0003439 xref: EMAPA:31159 xref: FMA:295652 @@ -198564,7 +198871,7 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "optic stalks" RELATED OMO:0003004 [ZFA:0000137] -synonym: "pedunculus opticus" RELATED LATIN [Wikipedia:Optic_stalk] +synonym: "pedunculus opticus" RELATED OMO:0003011 [Wikipedia:Optic_stalk] xref: AAO:0011077 xref: EHDAA2:0001318 xref: EHDAA:3816 @@ -198596,7 +198903,7 @@ subset: vertebrate_core synonym: "cephalic neural crest" EXACT [EMAPA:16091] synonym: "CNC" EXACT OMO:0003000 [XAO:0001001] synonym: "cranial NCC population" EXACT [] -synonym: "crista neuralis cranialis" RELATED LATIN [Wikipedia:Cranial_neural_crest] +synonym: "crista neuralis cranialis" RELATED OMO:0003011 [Wikipedia:Cranial_neural_crest] synonym: "head crest" RELATED [] synonym: "head NCC population" EXACT [] synonym: "head neural crest" RELATED [] @@ -198628,7 +198935,7 @@ synonym: "female human body" NARROW SENSU [FMA:67812] xref: AAO:0010030 xref: BILA:0000028 xref: CARO:0000028 -xref: FBbt:00007011 +xref: FBbt:00007011 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:67812 xref: HAO:0000028 xref: SCTID:362608006 @@ -198652,7 +198959,7 @@ synonym: "male human body" NARROW SENSU [FMA:67811] xref: AAO:0010033 xref: BILA:0000027 xref: CARO:0000027 -xref: FBbt:00007004 +xref: FBbt:00007004 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:67811 xref: HAO:0000027 xref: SCTID:362609003 @@ -198718,7 +199025,7 @@ def: "Portion of tissue composed of mesenchymal cells (motile cells that develop subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "mesenchyma" RELATED LATIN [Wikipedia:Mesenchyme] +synonym: "mesenchyma" RELATED OMO:0003011 [Wikipedia:Mesenchyme] synonym: "mesenchymal tissue" EXACT [] synonym: "mesenchyme tissue" EXACT [] synonym: "portion of mesenchymal tissue" EXACT [] @@ -199283,7 +199590,7 @@ subset: vertebrate_core synonym: "bones of cranium" EXACT [FMA:71325] synonym: "calvarium" RELATED [BTO:0001328] synonym: "epicranial plate" RELATED [] -synonym: "ossa cranii" EXACT LATIN [FMA:71325, FMA:TA] +synonym: "ossa cranii" EXACT OMO:0003011 [FMA:71325, FMA:TA] synonym: "set of bones of cranium" EXACT [FMA:71325] synonym: "skeletal system of head" RELATED [] synonym: "skull minus mandible" EXACT [] @@ -199295,6 +199602,7 @@ xref: EMAPA:17680 xref: FMA:71325 xref: MA:0000316 xref: MAT:0000340 +xref: MESH:D012886 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} xref: MIAA:0000340 xref: SCTID:181889008 xref: VHOG:0000334 @@ -199423,7 +199731,7 @@ name: blood nerve barrier namespace: uberon def: "Barrier between the perineurium of peripheral nerves and the vascular endothelium of endoneurial capillaries. The perineurium acts as a diffusion barrier, but ion permeability at the blood-nerve barrier is still higher than at the blood-brain barrier[GO]." [GO:0008065, Wikipedia:Blood-nerve_barrier] synonym: "blood-nerve barrier" EXACT [] -xref: MESH:D049428 +xref: MESH:D049428 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: Wikipedia:Blood-nerve_barrier is_a: UBERON:0000119 ! cell layer relationship: adjacent_to UBERON:0000179 ! haemolymphatic fluid @@ -199456,7 +199764,7 @@ synonym: "organ of gustatory system" EXACT [OBOL:automatic] synonym: "organ of taste system" EXACT [OBOL:automatic] synonym: "taste organ" EXACT [] synonym: "taste system organ" EXACT [OBOL:automatic] -xref: FBbt:00005159 +xref: FBbt:00005159 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:77853 is_a: UBERON:0000005 ! chemosensory organ intersection_of: UBERON:0000062 ! organ @@ -199933,8 +200241,8 @@ name: thoracic rib cage namespace: uberon def: "Subdivision of skeletal system that consists of all ribs in an organism connected to the sternum and the vertebrae. Some vertebrates have abdominal ribs (gastrialia), not connected to the vertebrate - these are not considered part of the rib case." [https://orcid.org/0000-0002-6601-2165] subset: pheno_slim -synonym: "cavea thoracis" EXACT LATIN [FMA:7480, FMA:TA] -synonym: "cavea thoracis" RELATED LATIN [Wikipedia:Human_rib_cage] +synonym: "cavea thoracis" EXACT OMO:0003011 [FMA:7480, FMA:TA] +synonym: "cavea thoracis" RELATED OMO:0003011 [Wikipedia:Human_rib_cage] synonym: "rib cage" EXACT [FMA:7480] synonym: "thoracic cage" EXACT [FMA:7480] xref: FMA:7480 @@ -199954,8 +200262,8 @@ id: UBERON:0003253 name: neck of rib namespace: uberon def: "The neck of the rib is the flattened portion which extends lateralward from the head; it is about 2.5 cm. long, and is placed in front of the transverse process of the lower of the two vertebrC& with which the head articulates. Its anterior surface is flat and smooth, its posterior rough for the attachment of the ligament of the neck, and perforated by numerous foramina. Of its two borders the superior presents a rough crest (crista colli costE) for the attachment of the anterior costotransverse ligament; its inferior border is rounded. On the posterior surface at the junction of the neck and body, and nearer the lower than the upper border, is an eminencebthe tubercle; it consists of an articular and a non-articular portion. The articular portion, the lower and more medial of the two, presents a small, oval surface for articulation with the end of the transverse process of the lower of the two vertebrC& to which the head is connected. The non-articular portion is a rough elevation, and affords attachment to the ligament of the tubercle. The tubercle is much more prominent in the upper than in the lower ribs." [Wikipedia:Neck_of_rib] -synonym: "collum costae" EXACT LATIN [Wikipedia:Neck_of_rib] -synonym: "collum costae" RELATED LATIN [Wikipedia:Neck_of_rib] +synonym: "collum costae" EXACT OMO:0003011 [Wikipedia:Neck_of_rib] +synonym: "collum costae" RELATED OMO:0003011 [Wikipedia:Neck_of_rib] synonym: "rib neck" EXACT [FMA:7576] xref: EMAPA:37826 {source="MA:th"} xref: FMA:7576 @@ -200880,7 +201188,7 @@ namespace: uberon def: "The submucous layer of the wall of the rectum." [BTO:0002114] synonym: "rectal submucosa" EXACT [FMA:15034] synonym: "rectum submucosa" EXACT [OBOL:automatic] -synonym: "tela submucosa recti" EXACT LATIN [BTO:0002114] +synonym: "tela submucosa recti" EXACT OMO:0003011 [BTO:0002114] xref: BTO:0002114 xref: EMAPA:27083 xref: FMA:15034 @@ -202422,7 +202730,7 @@ name: small intestine Peyer's patch namespace: uberon def: "Nodular lymphoid structures on the serosal surface of the small intestine." [http://orcid.org/0000-0002-6601-2165] synonym: "aggregated lymphoid follicle of small intestine" EXACT [FMA:15054] -synonym: "noduli lymphoidei aggregati intestini tenuis" EXACT LATIN [FMA:76466] +synonym: "noduli lymphoidei aggregati intestini tenuis" EXACT OMO:0003011 [FMA:76466] synonym: "Peyer's patch" BROAD [FMA:15054] synonym: "Peyer's patch of small bowel" EXACT [OBOL:automatic] synonym: "Peyer's patch of small intestine" EXACT [OBOL:automatic] @@ -202553,7 +202861,7 @@ synonym: "bone of upper extremity" RELATED [GAID:178] synonym: "bone organ of arm" EXACT [OBOL:automatic] xref: EMAPA:37303 {source="MA:th"} xref: MA:0000592 -xref: MESH:D050280 +xref: MESH:D050280 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} is_a: UBERON:0008962 ! forelimb bone intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0001460 ! arm @@ -202591,7 +202899,7 @@ xref: EMAPA:19019 xref: EMAPA:35924 xref: MA:0001482 xref: MA:0003159 -xref: MESH:D005147 +xref: MESH:D005147 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: NCIT:C63706 xref: SCTID:181799005 xref: UMLS:C0015455 {source="ncithesaurus:Facial_Bone"} @@ -202709,8 +203017,8 @@ name: artery of upper lip namespace: uberon def: "The superior labial artery (superior labial branch of facial artery) is larger and more tortuous than the inferior labial artery. It follows a similar course along the edge of the upper lip, lying between the mucous membrane and the Orbicularis oris, and anastomoses with the artery of the opposite side. It supplies the upper lip, and gives off in its course two or three vessels which ascend to the nose; a septal branch ramifies on the nasal septum as far as the point of the nose, and an alar branch supplies the ala of the nose." [Wikipedia:Superior_labial_artery] subset: human_reference_atlas -synonym: "arteria labialis superior" EXACT LATIN [Wikipedia:Superior_labial_artery] -synonym: "ramus labialis superior arteriae facialis" EXACT LATIN [Wikipedia:Superior_labial_artery] +synonym: "arteria labialis superior" EXACT OMO:0003011 [Wikipedia:Superior_labial_artery] +synonym: "ramus labialis superior arteriae facialis" EXACT OMO:0003011 [Wikipedia:Superior_labial_artery] synonym: "superior labial artery" EXACT [FMA:49570] synonym: "superior labial branch of facial artery" EXACT [FMA:49570] xref: EMAPA:37430 {source="MA:th"} @@ -202732,11 +203040,11 @@ name: artery of lower lip namespace: uberon def: "The inferior labial artery (inferior labial branch of facial artery) arises near the angle of the mouth; it passes upward and forward beneath the Triangularis and, penetrating the Orbicularis oris, runs in a tortuous course along the edge of the lower lip between this muscle and the mucous membrane. It supplies the labial glands, the mucous membrane, and the muscles of the lower lip; and anastomoses with the artery of the opposite side, and with the mental branch of the inferior alveolar artery." [Wikipedia:Inferior_labial_artery] subset: human_reference_atlas -synonym: "arteria labialis inferior" EXACT LATIN [Wikipedia:Inferior_labial_artery] +synonym: "arteria labialis inferior" EXACT OMO:0003011 [Wikipedia:Inferior_labial_artery] synonym: "inferior labial artery" EXACT [FMA:49567] synonym: "inferior labial branch of facial artery" EXACT [FMA:49567] synonym: "ramus labialis inferior (arteria facialis)" EXACT [FMA:TA] -synonym: "ramus labialis inferior arteriae facialis" EXACT LATIN [Wikipedia:Inferior_labial_artery] +synonym: "ramus labialis inferior arteriae facialis" EXACT OMO:0003011 [Wikipedia:Inferior_labial_artery] xref: EMAPA:37429 {source="MA:th"} xref: FMA:49567 xref: MA:0001916 @@ -202840,7 +203148,7 @@ def: "The inferior labial vein is the vein receiving blood from the upper lip." subset: human_reference_atlas synonym: "superior labial vein" EXACT [FMA:52538] synonym: "upper lip vein" EXACT [OBOL:automatic] -synonym: "vena labialis superior" EXACT LATIN [] +synonym: "vena labialis superior" EXACT OMO:0003011 [] xref: EMAPA:37204 {source="MA:th"} xref: FMA:52538 xref: MA:0002255 @@ -202860,8 +203168,8 @@ def: "The inferior labial vein is the vein receiving blood from the lower lip." subset: human_reference_atlas synonym: "inferior labial vein" EXACT [FMA:52541] synonym: "lower lip vein" EXACT [OBOL:automatic] -synonym: "vena labialis inferior" EXACT LATIN [] -synonym: "venae labiales inferiores" RELATED LATIN [Wikipedia:Inferior_labial_vein] +synonym: "vena labialis inferior" EXACT OMO:0003011 [] +synonym: "venae labiales inferiores" RELATED OMO:0003011 [Wikipedia:Inferior_labial_vein] xref: EMAPA:37202 {source="MA:th"} xref: FMA:52541 xref: MA:0002253 @@ -203689,8 +203997,8 @@ name: hindlimb skin namespace: uberon def: "A zone of skin that is part of a hindlimb [Automatically generated definition]." [OBOL:automatic] synonym: "hind limb skin" EXACT [OBOL:automatic] -synonym: "lower limb skin" EXACT [FMA:23102] synonym: "lower limb skin" EXACT [https://orcid.org/0000-0002-0819-0473] +synonym: "lower limb skin" EXACT [FMA:23102] synonym: "skin of hind limb" EXACT [OBOL:automatic] synonym: "skin of hindlimb" EXACT [OBOL:automatic] synonym: "skin of lower extremity" EXACT [OBOL:automatic] @@ -204953,7 +205261,7 @@ def: "A portion of connective tissue that is part of a foot [Automatically gener synonym: "connective tissue of foot" EXACT [OBOL:automatic] synonym: "connective tissue of terminal segment of free lower limb" EXACT [OBOL:automatic] synonym: "foot connective tissue" EXACT [MA:0000644] -synonym: "textus connectivus of pes" EXACT LATIN [OBOL:automatic] +synonym: "textus connectivus of pes" EXACT OMO:0003011 [OBOL:automatic] xref: EMAPA:37329 {source="MA:th"} xref: MA:0000644 is_a: UBERON:0003589 ! hindlimb connective tissue @@ -205077,7 +205385,7 @@ subset: pheno_slim synonym: "cartilage of the trachea" RELATED [Wikipedia:Tracheal_rings] synonym: "cartilage of trachea" EXACT [OBOL:automatic] synonym: "cartilage of windpipe" EXACT [OBOL:automatic] -synonym: "cartilagines tracheales" RELATED LATIN [Wikipedia:Tracheal_rings] +synonym: "cartilagines tracheales" RELATED OMO:0003011 [Wikipedia:Tracheal_rings] synonym: "cartilaginous ring of trachea" EXACT [EMAPA:18699] synonym: "cartilaginous trachea cartilage" EXACT [OBOL:automatic] synonym: "cartilago trachealis" EXACT [FMA:7434] @@ -205574,6 +205882,7 @@ id: UBERON:0003661 name: limb muscle namespace: uberon def: "Any muscle organ that is part of a limb [Automatically generated definition]." [OBOL:automatic] +subset: human_reference_atlas subset: pheno_slim synonym: "limb muscle organ" EXACT [OBOL:accepted] synonym: "limb skeletal muscle" EXACT [OBOL:exploratory] @@ -205585,6 +205894,7 @@ intersection_of: UBERON:0014892 ! skeletal muscle organ, vertebrate intersection_of: part_of UBERON:0002101 ! limb relationship: contributes_to_morphology_of UBERON:0001015 ! musculature relationship: part_of UBERON:0004480 {source="prolog"} ! musculature of limb +relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: UBERON:0003662 @@ -205619,6 +205929,7 @@ name: hindlimb muscle namespace: uberon def: "Any muscle organ that is part of a hindlimb [Automatically generated definition]." [OBOL:automatic] subset: efo_slim +subset: human_reference_atlas synonym: "free lower limb muscle" EXACT [FMA:37368] synonym: "hind limb muscle organ" EXACT [OBOL:automatic] synonym: "hindlimb muscle organ" EXACT [OBOL:automatic] @@ -205639,6 +205950,7 @@ is_a: UBERON:0014795 ! pelvic appendage muscle intersection_of: UBERON:0014892 ! skeletal muscle organ, vertebrate intersection_of: part_of UBERON:0002103 ! hindlimb relationship: part_of UBERON:0004482 {source="prolog"} ! musculature of lower limb +relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: UBERON:0003664 @@ -205697,7 +206009,7 @@ namespace: uberon def: "A collection of teeth arranged in some pattern in the mouth or other part of the body. The arrangement may be a simple row, a collection of rows, or a more elaborate structure, such as a toooth whorl." [http://orcid.org/0000-0002-6601-2165] subset: pheno_slim synonym: "collection of teeth" RELATED [] -synonym: "dentes" EXACT LATIN [FMA:75150, FMA:TA] +synonym: "dentes" EXACT OMO:0003011 [FMA:75150, FMA:TA] synonym: "set of teeth" EXACT [FMA:75150] synonym: "teeth" EXACT [FMA:75150] synonym: "teeth" RELATED [] @@ -205743,7 +206055,7 @@ name: abdominal cavity namespace: uberon def: "The part of the ventral body cavity that is within the abdomen proper (excluding the pelvic cavity)." [UBERON:cjm] subset: efo_slim -synonym: "cavitas abdominis" RELATED LATIN [GAID:17, Wikipedia:Abdominal_cavity] +synonym: "cavitas abdominis" RELATED OMO:0003011 [GAID:17, Wikipedia:Abdominal_cavity] synonym: "cavity of abdominal compartment" EXACT [FMA:12266] synonym: "cavity of compartment of abdomen" EXACT [FMA:12266] synonym: "space of abdominal compartment" EXACT [FMA:12266] @@ -205803,7 +206115,7 @@ comment: Design pattern notes: check whether this fits the foramen design patter subset: pheno_slim subset: vertebrate_core xref: AAO:0010826 -xref: BTO:0006035 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: BTO:0006035 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: EMAPA:37868 {source="MA:th"} xref: FMA:75306 xref: GAID:228 @@ -205845,12 +206157,12 @@ id: UBERON:0003691 name: epidural space namespace: uberon def: "The outermost part of the spinal canal. It is the space within the canal (formed by the surrounding vertebrae) lying outside the dura mater." [Wikipedia:Epidural_space] -synonym: "cavum epidurale" EXACT LATIN [Wikipedia:Epidural_space] -synonym: "cavum extradurale" EXACT LATIN [Wikipedia:Epidural_space] +synonym: "cavum epidurale" EXACT OMO:0003011 [Wikipedia:Epidural_space] +synonym: "cavum extradurale" EXACT OMO:0003011 [Wikipedia:Epidural_space] synonym: "epidural cavity" RELATED [Wikipedia:Epidural_space] synonym: "extradural space" EXACT [FMA:71228] -synonym: "spatium epidurale" EXACT LATIN [Wikipedia:Epidural_space] -synonym: "spatium extradurale" EXACT LATIN [FMA:71228, FMA:TA] +synonym: "spatium epidurale" EXACT OMO:0003011 [Wikipedia:Epidural_space] +synonym: "spatium extradurale" EXACT OMO:0003011 [FMA:71228, FMA:TA] xref: FMA:71228 xref: GAID:243 xref: MESH:D004824 @@ -205873,7 +206185,7 @@ name: acromioclavicular joint namespace: uberon def: "Any joint connecting the acromonion of the scapula and clavicle." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Acromioclavicular_joint] synonym: "acromioclavicular articulation" RELATED [Wikipedia:Acromioclavicular_joint] -synonym: "articulatio acromioclavicularis" RELATED LATIN [Wikipedia:Acromioclavicular_joint] +synonym: "articulatio acromioclavicularis" RELATED OMO:0003011 [Wikipedia:Acromioclavicular_joint] synonym: "scapuloclavicular articulation" RELATED [Wikipedia:Acromioclavicular_joint] xref: FMA:25898 xref: GAID:249 @@ -205927,7 +206239,7 @@ name: metacarpophalangeal joint namespace: uberon def: "The metacarpophalangeal joints (MCP) are of the condyloid kind, formed by the reception of the rounded heads of the metacarpal bones into shallow cavities on the proximal ends of the first phalanges, with the exception of that of the thumb, which presents more of the characters of a ginglymoid joint. Arthritis of the MCP is a distinguishing feature of Rheumatoid Arthritis, as opposed to the distal interphalangeal joint in osteoarthritis. [WP,unvetted]." [Wikipedia:Metacarpophalangeal_joint] subset: pheno_slim -synonym: "articulationes metacarpophalangeae" RELATED LATIN [Wikipedia:Metacarpophalangeal_joint] +synonym: "articulationes metacarpophalangeae" RELATED OMO:0003011 [Wikipedia:Metacarpophalangeal_joint] synonym: "carpometacarpophalangeal joint" NARROW SENSU [NCBITaxon:8782] synonym: "knuckle" EXACT [https://orcid.org/0000-0001-5208-3432] synonym: "knuckles" EXACT OMO:0003004 [https://orcid.org/0000-0001-5208-3432] @@ -205962,7 +206274,7 @@ id: UBERON:0003696 name: metatarsophalangeal joint namespace: uberon def: "The metatarsophalangeal articulations are the joints between the metatarsal bones of the foot and the proximal bones of the toes . They are condyloid joints meaning an elliptical or rounded surface (of the metatarsal bones) come close to the shallow cavities (of the proximal phalanges). The ligaments are the plantar and two collateral." [Wikipedia:Metatarsophalangeal_articulations] -synonym: "articulationes metatarsophalangeae" RELATED LATIN [Wikipedia:Metatarsophalangeal_articulations] +synonym: "articulationes metatarsophalangeae" RELATED OMO:0003011 [Wikipedia:Metatarsophalangeal_articulations] synonym: "metatarsal joint" RELATED [FMA:35222] synonym: "metatarsal-phalangeal joint" EXACT [PHENOSCAPE:ad] synonym: "metatarsalphalangeal joint" RELATED [Wikipedia:Metatarsophalangeal_articulations] @@ -205997,7 +206309,7 @@ subset: pheno_slim synonym: "abdominal wall proper" RELATED [FMA:10429] synonym: "layers of the abdominal wall" RELATED [Wikipedia:Abdominal_wall] synonym: "paries abdominalis" EXACT [Wikipedia:Abdominal_wall] -synonym: "paries abdominalis" RELATED LATIN [Wikipedia:Abdominal_wall] +synonym: "paries abdominalis" RELATED OMO:0003011 [Wikipedia:Abdominal_wall] synonym: "wall of abdomen" EXACT [FMA:259054] synonym: "wall of abdomen proper" EXACT [FMA:10429] xref: EMAPA:37064 {source="MA:th"} @@ -206070,7 +206382,7 @@ subset: pheno_slim synonym: "arterial circle" BROAD [Wikipedia:Circle_of_Willis] synonym: "arterial circle of Willis" EXACT [] synonym: "cerebral arterial circle" EXACT [GAID:486] -synonym: "circulus arteriosus cerebri" RELATED LATIN [Wikipedia:Circle_of_Willis] +synonym: "circulus arteriosus cerebri" RELATED OMO:0003011 [Wikipedia:Circle_of_Willis] synonym: "Willis circle" RELATED [GAID:486] xref: EHDAA2:0000252 xref: EHDAA:9758 @@ -206099,8 +206411,8 @@ synonym: "innominate trunk" RELATED [Wikipedia:Brachiocephalic_vein] synonym: "innominate vein" EXACT [FMA:4723] synonym: "innominate vein" RELATED [GAID:529, Wikipedia:Brachiocephalic_vein] synonym: "innominate veins" RELATED [Wikipedia:Brachiocephalic_vein] -synonym: "vena brachiocephalica" RELATED LATIN [Wikipedia:Brachiocephalic_vein] -synonym: "venae anonyma" RELATED LATIN [Wikipedia:Brachiocephalic_vein] +synonym: "vena brachiocephalica" RELATED OMO:0003011 [Wikipedia:Brachiocephalic_vein] +synonym: "venae anonyma" RELATED OMO:0003011 [Wikipedia:Brachiocephalic_vein] xref: EHDAA2:0000182 xref: EHDAA:9868 xref: FMA:4723 @@ -206149,8 +206461,8 @@ namespace: uberon def: "A vein arising from the splenic trabecular vein in the hilum of the spleen that drains into the portal vein." [ncithesaurus:Splenic_Vein] subset: human_reference_atlas synonym: "lienal vein" RELATED [MA:0002164, Wikipedia:Splenic_vein] -synonym: "vena lienalis" RELATED LATIN [Wikipedia:Splenic_vein] -synonym: "vena splenica" EXACT LATIN [FMA:14331, FMA:TA] +synonym: "vena lienalis" RELATED OMO:0003011 [Wikipedia:Splenic_vein] +synonym: "vena splenica" EXACT OMO:0003011 [FMA:14331, FMA:TA] xref: EMAPA:37226 {source="MA:th"} xref: FMA:14331 xref: GAID:541 @@ -206225,7 +206537,7 @@ name: recurrent laryngeal nerve namespace: uberon def: "A branch of the vagus nerve that supplies motor function and sensation to the larynx (voice box). It travels within the endoneurium. It is the nerve of the 6th Branchial Arch." [Wikipedia:Recurrent_laryngeal_nerve] synonym: "inferior laryngeal nerve" RELATED [GAID:804] -synonym: "nervus laryngeus recurrens" EXACT LATIN [Wikipedia:Recurrent_laryngeal_nerve] +synonym: "nervus laryngeus recurrens" EXACT OMO:0003011 [Wikipedia:Recurrent_laryngeal_nerve] synonym: "ramus recurrens" RELATED [AAO:0010754] synonym: "recurrent laryngeal nerve from vagus nerve" EXACT [] synonym: "recurrent nerve" BROAD [Wikipedia:Recurrent_laryngeal_nerve] @@ -206288,8 +206600,8 @@ id: UBERON:0003726 name: thoracic nerve namespace: uberon def: "The twelve spinal nerves on each side of the thorax. They include eleven INTERCOSTAL NERVES and one subcostal nerve. Both sensory and motor, they supply the muscles and skin of the thoracic and abdominal walls." [MESH:A08.800.800.720.800] -synonym: "nervi thoracici" RELATED LATIN [Wikipedia:Thoracic_nerves] -synonym: "nervus thoracis" EXACT LATIN [FMA:5860, FMA:TA] +synonym: "nervi thoracici" RELATED OMO:0003011 [Wikipedia:Thoracic_nerves] +synonym: "nervus thoracis" EXACT OMO:0003011 [FMA:5860, FMA:TA] synonym: "pectoral nerve" RELATED [GAID:857] synonym: "thoracic spinal nerve" EXACT [FMA:5860] xref: FMA:5860 @@ -206310,7 +206622,7 @@ namespace: uberon def: "The intercostal nerves are the anterior divisions (rami anteriores; ventral divisions) of the thoracic spinal nerves from T1 to T11. Each nerve is connected with the adjoining ganglion of the sympathetic trunk by a gray and a white ramus communicans. The intercostal nerves are distributed chiefly to the thoracic pleura and abdominal peritoneum and differ from the anterior divisions of the other spinal nerves in that each pursues an independent course without plexus formation. The first two nerves supply fibers to the upper limb in addition to their thoracic branches; the next four are limited in their distribution to the parietes of the thorax; the lower five supply the parietes of the thorax and abdomen. The 7th intercostal nerve terminates at the xyphoid process, at the lower end of the sternum. The 10th intercostal nerve terminates at the umbilicus. The twelfth thoracic is distributed to the abdominal wall and groin. [WP,unvetted]." [Wikipedia:Intercostal_nerves] synonym: "anterior ramus of thoracic nerve" EXACT [FMA:6028] synonym: "anterior ramus of thoracic spinal nerve" EXACT [FMA:6028] -synonym: "nervi intercostales" RELATED LATIN [Wikipedia:Intercostal_nerves] +synonym: "nervi intercostales" RELATED OMO:0003011 [Wikipedia:Intercostal_nerves] synonym: "ramus anterior, nervus thoracicus" EXACT [FMA:6028] synonym: "thoracic anterior ramus" EXACT [FMA:6028] synonym: "ventral ramus of thoracic spinal nerve" EXACT [FMA:6028] @@ -206366,8 +206678,8 @@ synonym: "mucous membrane of mouth" EXACT [FMA:59660] synonym: "oral mucosa" RELATED [GAID:951] synonym: "oral mucous membrane" EXACT [] synonym: "oral part of viscerocranial mucosa" EXACT [FMA:59660] -synonym: "tunica mucosa oris" EXACT LATIN [FMA:59660, FMA:TA] -synonym: "tunica mucosa oris" RELATED LATIN [Wikipedia:Oral_mucosa] +synonym: "tunica mucosa oris" EXACT OMO:0003011 [FMA:59660, FMA:TA] +synonym: "tunica mucosa oris" RELATED OMO:0003011 [Wikipedia:Oral_mucosa] xref: BTO:0002860 xref: CALOHA:TS-0716 xref: EMAPA:26937 @@ -206441,7 +206753,7 @@ synonym: "forelimb propodium" EXACT [] synonym: "forelimb stylopodial element" EXACT [MA:th] synonym: "forelimb stylopodium" EXACT [OBOL:automatic] synonym: "proximal segment of free upper limb" EXACT [] -synonym: "regio brachialis" EXACT LATIN [FMA:24890, FMA:TA] +synonym: "regio brachialis" EXACT OMO:0003011 [FMA:24890, FMA:TA] synonym: "stylopod of arm" EXACT [] synonym: "stylopod of forelimb" EXACT [] synonym: "upper arm" EXACT HUMAN_PREFERRED [MA:0000035] @@ -206512,6 +206824,7 @@ xref: NCIT:C32974 xref: SCTID:244015008 xref: UMLS:C1140621 {source="ncithesaurus:Leg"} xref: VHOG:0000348 +xref: VO:0010971 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: VSAO:0005060 xref: Wikipedia:Forearm is_a: UBERON:0002471 ! zeugopod @@ -207208,7 +207521,7 @@ subset: pheno_slim subset: vertebrate_core synonym: "arcus vertebra" EXACT [Wikipedia:Vertebral_arch] synonym: "arcus vertebrae" EXACT OMO:0003004 [Wikipedia:Vertebral_arch] -synonym: "arcus vertebrae" RELATED LATIN [Wikipedia:Vertebral_arch] +synonym: "arcus vertebrae" RELATED OMO:0003011 [Wikipedia:Vertebral_arch] synonym: "arcus vertebrae (vertebralis)" EXACT [FMA:11946] synonym: "dorsal arcocentrum" EXACT [ZFA:0001066] synonym: "vertebra dorsal arch" RELATED [MA:0001453] @@ -207247,7 +207560,7 @@ synonym: "middle manual phalanx" EXACT [] synonym: "middle phalanx of finger" EXACT [FMA:75817] synonym: "middle phalanx of hand" EXACT [MA:0001394] synonym: "middle phalanx of manual digit" EXACT [] -synonym: "phalanx media manus" EXACT LATIN [FMA:75817, FMA:TA] +synonym: "phalanx media manus" EXACT OMO:0003011 [FMA:75817, FMA:TA] xref: EMAPA:37306 {source="MA:th"} xref: FMA:75817 xref: MA:0001394 @@ -207274,7 +207587,7 @@ synonym: "distal phalanx of finger" EXACT [FMA:75818] synonym: "distal phalanx of hand" EXACT [] synonym: "distal phalanx of manual digit" EXACT [] synonym: "hand distal phalanx" EXACT [MA:0001388] -synonym: "phalanx distalis manus" EXACT LATIN [FMA:75818, FMA:TA] +synonym: "phalanx distalis manus" EXACT OMO:0003011 [FMA:75818, FMA:TA] synonym: "terminal phalanx of hand" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "ungual phalanx of hand" EXACT [http://www.medilexicon.com/medicaldictionary.php?t=67679] xref: EMAPA:35393 @@ -207301,7 +207614,7 @@ synonym: "foot middle phalanx" EXACT [MA:0001386] synonym: "middle pedal phalanx" EXACT [] synonym: "middle phalanx of foot" EXACT [] synonym: "middle phalanx of toe" EXACT [FMA:75829] -synonym: "phalanx media pedis" EXACT LATIN [FMA:75829, FMA:TA] +synonym: "phalanx media pedis" EXACT OMO:0003011 [FMA:75829, FMA:TA] xref: EMAPA:37311 {source="MA:th"} xref: FMA:75829 xref: MA:0001386 @@ -207324,7 +207637,7 @@ synonym: "distal pedal phalanx" EXACT [] synonym: "distal phalanx of foot" EXACT [] synonym: "distal phalanx of toe" EXACT [FMA:75830] synonym: "foot distal phalanx" EXACT [MA:0001380] -synonym: "phalanx distalis pedis" EXACT LATIN [FMA:75830, FMA:TA] +synonym: "phalanx distalis pedis" EXACT OMO:0003011 [FMA:75830, FMA:TA] synonym: "terminal phalanx of foot" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "terminal phalanx of hindlimb" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "ungual phalanx of foot" EXACT [http://www.medilexicon.com/medicaldictionary.php?t=67679] @@ -207349,7 +207662,7 @@ namespace: uberon def: "A proximal phalanx that is part of a pedal digit [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "foot proximal phalanx" EXACT [MA:0001387] -synonym: "phalanx proximalis pedis" EXACT LATIN [FMA:75828, FMA:TA] +synonym: "phalanx proximalis pedis" EXACT OMO:0003011 [FMA:75828, FMA:TA] synonym: "proximal pedal phalanx" EXACT [] synonym: "proximal phalanx of foot" EXACT [] synonym: "proximal phalanx of foot digit" EXACT [] @@ -207448,7 +207761,7 @@ synonym: "mammalian oviduct" EXACT [https://sourceforge.net/p/geneontology/ontol synonym: "paramesonephric duct of female" RELATED [EMAPA:35660] synonym: "salpinges" BROAD OMO:0003004 [] synonym: "salpinx" BROAD [] -synonym: "tuba uterina" RELATED LATIN [Wikipedia:Fallopian_tube] +synonym: "tuba uterina" RELATED OMO:0003011 [Wikipedia:Fallopian_tube] synonym: "uterine tube (sensu Mammalia)" EXACT [] xref: CALOHA:TS-0732 xref: EHDAA2:0000504 @@ -207635,7 +207948,7 @@ synonym: "neural retina" EXACT [XAO:0003216, ZFA:0000046] synonym: "neural retinal epithelium" RELATED [MA:000027] synonym: "neuroretina" EXACT [ZFA:0000046] synonym: "stratum nervosum (retina)" EXACT [FMA:58628] -synonym: "stratum nervosum retinae" EXACT LATIN [FMA:58628, FMA:TA] +synonym: "stratum nervosum retinae" EXACT OMO:0003011 [FMA:58628, FMA:TA] xref: AAO:0011095 xref: BTO:0000929 xref: CALOHA:TS-0685 @@ -207716,7 +208029,7 @@ synonym: "choroid plexus epithelial tissue" EXACT [OBOL:automatic] synonym: "epithelial tissue of chorioid plexus of cerebral hemisphere" EXACT [OBOL:automatic] synonym: "epithelial tissue of choroid plexus" EXACT [OBOL:automatic] synonym: "epithelium of choroid plexus" EXACT [FMA:242811] -xref: BTO:0006008 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: BTO:0006008 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: EMAPA:36608 xref: FMA:242811 xref: MA:0000824 @@ -207749,7 +208062,7 @@ def: "Epithelial tubes transport gases, liquids and cells from one site to anoth synonym: "epithelial or endothelial tube" EXACT [] xref: AEO:0000114 xref: EHDAA2:0003114 -xref: FBbt:00007474 +xref: FBbt:00007474 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0000025 ! tube is_a: UBERON:0000483 ! epithelium intersection_of: UBERON:0000483 ! epithelium @@ -207953,7 +208266,7 @@ synonym: "gut epithelium" EXACT [EHDAA2:0004567, MA:0003201, ZFA:0005123] xref: BTO:0000956 xref: EHDAA2:0004567 xref: EMAPA:32928 -xref: FBbt:00047166 +xref: FBbt:00047166 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: MA:0003201 xref: NCIT:C12963 xref: TAO:0005123 @@ -208034,7 +208347,7 @@ synonym: "gland of reproductive system" EXACT [OBOL:automatic] synonym: "reproductive gland" EXACT [MA:0001751] synonym: "reproductive system gland" EXACT [OBOL:automatic] synonym: "sex gland" EXACT [MP:0000653] -xref: BTO:0006162 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: BTO:0006162 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: MA:0001751 is_a: UBERON:0002530 ! gland is_a: UBERON:0005156 ! reproductive structure @@ -208197,6 +208510,7 @@ name: internal female genitalia namespace: uberon def: "The internal feminine genital organs, including the ovaries, uterine tubes, uterus, uterine cervix, and vagina." [MP:0009209] comment: TODO: Relabel. Make distinct organ class. See https://github.com/obophenotype/uberon/issues/547 +subset: human_reference_atlas subset: organ_slim subset: pheno_slim synonym: "female internal genitalia" EXACT [FMA:45654] @@ -208210,6 +208524,7 @@ is_a: UBERON:0003134 ! female reproductive organ is_a: UBERON:0004175 ! internal genitalia intersection_of: UBERON:0004175 ! internal genitalia intersection_of: part_of UBERON:0000474 ! female reproductive system +relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: UBERON:0003978 @@ -208239,7 +208554,7 @@ synonym: "cerebellar fissures" RELATED OMO:0003004 [BAMS:CBf] synonym: "cerebellar fissures set" RELATED OMO:0003004 [FMA:77789] synonym: "cerebellar sulci" RELATED OMO:0003004 [HBA:9406] synonym: "cerebellar sulcus" RELATED [] -synonym: "fissurae cerebelli" EXACT LATIN [FMA:77789, FMA:TA] +synonym: "fissurae cerebelli" EXACT OMO:0003011 [FMA:77789, FMA:TA] synonym: "set of cerebellar fissures" RELATED OMO:0003004 [FMA:77789] synonym: "sulcus of cerebellum" RELATED [] xref: BAMS:CBf @@ -208296,7 +208611,7 @@ synonym: "infundibulum" BROAD INCONSISTENT [] synonym: "infundibulum of fallopian tube" NARROW [FMA:18307] synonym: "infundibulum of oviduct" EXACT [FMA:18307] synonym: "infundibulum of uterine tube" EXACT [FMA:18307] -synonym: "infundibulum tubae uterinae" RELATED LATIN [Wikipedia:Infundibulum_of_uterine_tube] +synonym: "infundibulum tubae uterinae" RELATED OMO:0003011 [Wikipedia:Infundibulum_of_uterine_tube] xref: EMAPA:29897 xref: FMA:18307 xref: SCTID:362262001 @@ -208355,7 +208670,7 @@ relationship: contributes_to_morphology_of UBERON:0002240 ! spinal cord id: UBERON:0004001 name: olfactory bulb layer namespace: uberon -def: "." [MP:0009946] +def: "Missing definition for term UBERON:0004001. Please replace it using linked reference." [MP:0009946] subset: pheno_slim synonym: "cytoarchitectural part of olfactory bulb" EXACT [NLXANAT:20090402] xref: EMAPA:37917 {source="MA:th"} @@ -208390,10 +208705,10 @@ subset: pheno_slim synonym: "cutis plate" EXACT [Wikipedia:Cutis_plate] synonym: "dermatomal mesenchyme" EXACT [Wikipedia:Cutis_plate] synonym: "epimere mesoderm" RELATED [] -synonym: "mesenchyma dermatomiale" RELATED LATIN [Wikipedia:Dermatomal_mesenchyme] +synonym: "mesenchyma dermatomiale" RELATED OMO:0003011 [Wikipedia:Dermatomal_mesenchyme] xref: AAO:0011028 xref: AEO:0001017 -xref: BTO:0006248 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: BTO:0006248 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: EHDAA2_RETIRED:0003428 xref: EHDAA:1719 xref: EHDAA:1725 @@ -208482,6 +208797,21 @@ xref: DHBA:10550 xref: EMAPA:37471 {source="MA:th"} xref: PBA:128012834 is_a: UBERON:0002050 ! embryonic structure +disjoint_from: UBERON:0004025 {source="lexical"} ! lateral ganglionic eminence +relationship: contributes_to_morphology_of UBERON:0004023 ! ganglionic eminence +relationship: part_of UBERON:0004023 ! ganglionic eminence + +[Term] +id: UBERON:0004025 +name: lateral ganglionic eminence +namespace: uberon +def: "A distinct elevation of a transient proliferating cell mass of the fetal subventricular zone; this mass contributes most of its cells to the striatum; however, neocortex, thalamus, septum and olfactory bulb neurons are also partly derived from the LGE." [MP:0004277] +subset: pheno_slim +synonym: "LGE" BROAD OMO:0003000 [PMID:23375746] +xref: DHBA:10551 +xref: EMAPA:37470 {source="MA:th"} +xref: PBA:128012822 +is_a: UBERON:0002050 ! embryonic structure relationship: contributes_to_morphology_of UBERON:0004023 ! ganglionic eminence relationship: part_of UBERON:0004023 ! ganglionic eminence @@ -208513,9 +208843,11 @@ xref: EMAPA:31872 xref: NCIT:C34123 xref: SCTID:256391000 xref: UMLS:C0230972 {source="ncithesaurus:Chorionic_Plate"} +is_a: UBERON:0005156 ! reproductive structure is_a: UBERON:0005292 ! extraembryonic tissue relationship: contributes_to_morphology_of UBERON:0003124 ! chorion membrane relationship: part_of UBERON:0003124 ! chorion membrane +relationship: part_of UBERON:8600038 ! placental disc relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens property_value: depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Placenta.glb" xsd:anyURI @@ -208534,6 +208866,7 @@ xref: EMAPA:32703 xref: https://upload.wikimedia.org/wikipedia/commons/thumb/a/ac/Corticogenesis_in_a_wild-type_mouse_with_captions_in_english_copy.png/360px-Corticogenesis_in_a_wild-type_mouse_with_captions_in_english_copy.png xref: neuronames:3233 xref: PBA:294021932 +xref: VO:0011276 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: Wikipedia:Subplate is_a: UBERON:0014950 ! layer of developing cerebral cortex intersection_of: UBERON:0014950 ! layer of developing cerebral cortex @@ -208600,7 +208933,7 @@ name: semicircular canal ampulla namespace: uberon def: "The spherical enlargement at the base of each semicircular canal where they connect with the utricle, containing the crista ampullaris which detects movement of the fluid within the canals." [MP:0008488, Wikipedia:Osseous_ampullae] subset: pheno_slim -synonym: "ampullae osseae" RELATED LATIN [Wikipedia:Osseous_ampullae] +synonym: "ampullae osseae" RELATED OMO:0003011 [Wikipedia:Osseous_ampullae] synonym: "membraneous ampulla of the semicircular duct" RELATED [MP:0008488] synonym: "semicircular duct ampulla" RELATED [MA:0002770] xref: EMAPA:32831 @@ -208814,7 +209147,7 @@ synonym: "embryonic frontonasal prominence" EXACT [http://orcid.org/0000-0002-66 synonym: "forebrain prominence" RELATED [MP:0009901] synonym: "frontonasal mass" RELATED [MP:0009901] synonym: "frontonasal process" RELATED [MP:0009901] -synonym: "prominentia frontonasalis" RELATED LATIN [Wikipedia:Frontonasal_prominence] +synonym: "prominentia frontonasalis" RELATED OMO:0003011 [Wikipedia:Frontonasal_prominence] xref: EHDAA2:0000578 xref: EHDAA:4778 xref: EMAPA:16681 @@ -208837,7 +209170,7 @@ subset: pheno_slim synonym: "lateral nasal process" EXACT [EHDAA2:0000916] synonym: "lateral nasal swelling" RELATED [https://orcid.org/0000-0002-6601-2165] synonym: "latero-nasal process" EXACT [EMAPA:16805] -synonym: "prominentia nasalis lateralis" RELATED LATIN [Wikipedia:Lateral_nasal_prominence] +synonym: "prominentia nasalis lateralis" RELATED OMO:0003011 [Wikipedia:Lateral_nasal_prominence] xref: EHDAA2:0000916 xref: EHDAA:4786 xref: EMAPA:16805 @@ -208860,7 +209193,7 @@ synonym: "medial nasal process" EXACT [EHDAA2:0001076] synonym: "medial nasal swelling" RELATED [https://orcid.org/0000-0002-6601-2165] synonym: "medial-nasal process" EXACT [EMAPA:16808] synonym: "nasomedial prominence" RELATED [https://orcid.org/0000-0002-6601-2165] -synonym: "prominentia nasalis medialis" EXACT LATIN [Wikipedia:Medial_nasal_prominence] +synonym: "prominentia nasalis medialis" EXACT OMO:0003011 [Wikipedia:Medial_nasal_prominence] xref: EHDAA2:0001076 xref: EHDAA:4792 xref: EMAPA:16808 @@ -208992,7 +209325,7 @@ subset: human_reference_atlas subset: pheno_slim synonym: "collecting duct system" EXACT [Wikipedia:Collecting_duct_system] synonym: "kidney collecting duct system" EXACT [Wikipedia:Collecting_duct_system] -synonym: "tubulus renalis colligens" RELATED LATIN [Wikipedia:Collecting_duct_system] +synonym: "tubulus renalis colligens" RELATED OMO:0003011 [Wikipedia:Collecting_duct_system] xref: FMA:265239 xref: SCTID:279371005 xref: Wikipedia:Collecting_duct_system @@ -209011,7 +209344,7 @@ synonym: "alveolar body" EXACT [MP:0004189] synonym: "alveolar bone" EXACT [MP:0004189] synonym: "alveolar margin" EXACT [] synonym: "alveolar process" EXACT [] -synonym: "margo alveolaris" EXACT LATIN [] +synonym: "margo alveolaris" EXACT OMO:0003011 [] xref: BTO:0001383 xref: EMAPA:35118 xref: FMA:313923 @@ -209106,7 +209439,7 @@ name: tympanic cavity namespace: uberon def: "Small cavity surrounding the bones of the middle ear." [Wikipedia:Tympanic_cavity] synonym: "anatomical cavity of middle ear" EXACT [OBOL:automatic] -synonym: "cavitas tympani" EXACT LATIN [Wikipedia:Tympanic_cavity] +synonym: "cavitas tympani" EXACT OMO:0003011 [Wikipedia:Tympanic_cavity] synonym: "cavitas tympanica" RELATED [BTO:0002098] synonym: "cavity of middle ear" EXACT [OBOL:automatic] synonym: "middle ear cavity" EXACT [OBOL:automatic] @@ -209449,7 +209782,7 @@ relationship: part_of UBERON:0002129 ! cerebellar cortex id: UBERON:0004133 name: salivatory nucleus namespace: uberon -def: "." [GO:0021751] +def: "Missing definition for term UBERON:0004133. Please replace it using linked reference." [GO:0021751] synonym: "salivary nucleus" EXACT [GO:0021751] is_a: UBERON:0006331 ! brainstem nucleus is_a: UBERON:0009662 ! hindbrain nucleus @@ -209719,6 +210052,7 @@ name: internal genitalia namespace: uberon def: "The internal genitalia are the internal sex organs such as the uterine tube, the uterus and the vagina in female mammals, and the testis, seminal vesicle, ejaculatory duct and prostate in male mammals." [GO:0035260] comment: TODO: make a subdivision of reproductive system. Relabel. See https://github.com/obophenotype/uberon/issues/547 +subset: human_reference_atlas subset: organ_slim subset: pheno_slim synonym: "internal genitalia" EXACT [] @@ -209727,6 +210061,7 @@ synonym: "internal reproductive organ" RELATED [] synonym: "internal sex organ" RELATED [] xref: FMA:45652 is_a: UBERON:0003133 ! reproductive organ +relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: UBERON:0004176 @@ -210061,6 +210396,7 @@ subset: pheno_slim synonym: "SSB" EXACT OMO:0003000 [] synonym: "stage II nephron" EXACT [http://www.gudmap.org/Organ_Summaries/Metanephros/Renal_vesicle.html] xref: EMAPA:27756 +xref: VO:0010896 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: ZFA:0005589 is_a: UBERON:0005423 ! developing anatomical structure relationship: develops_from UBERON:0004198 {source="GO"} ! comma-shaped body @@ -210083,7 +210419,7 @@ synonym: "medullary pyramid" RELATED [] synonym: "pyramid" BROAD [GO:0072056] synonym: "pyramid of Malphigi" RELATED MISSPELLING [ncithesaurus:Pyramid_of_Malpighi] synonym: "pyramid of Malpighi" RELATED [UBERON:cjm] -synonym: "pyramides renales" RELATED LATIN [Wikipedia:Renal_pyramids] +synonym: "pyramides renales" RELATED OMO:0003011 [Wikipedia:Renal_pyramids] synonym: "pyramis renalis" RELATED [BTO:0003926] synonym: "renal medullary region" RELATED [FMA:258870] synonym: "renal pyramid" EXACT [Wikipedia:Renal_pyramids] @@ -210120,7 +210456,7 @@ synonym: "inner stripe of medulla of kidney" EXACT [FMA:76663] synonym: "inner stripe of outer medulla" EXACT [EMAPA:29675] synonym: "inner stripe of renal medulla" EXACT [FMA:76663] synonym: "outer medulla inner stripe" EXACT [MA:0002626] -synonym: "stria interna medullae renalis" EXACT LATIN [FMA:76663, FMA:TA] +synonym: "stria interna medullae renalis" EXACT OMO:0003011 [FMA:76663, FMA:TA] xref: EMAPA:29675 xref: FMA:76663 xref: MA:0002626 @@ -210141,7 +210477,7 @@ synonym: "outer stripe" EXACT [GO:0072058] synonym: "outer stripe of medulla of kidney" EXACT [FMA:76662] synonym: "outer stripe of outer medulla" EXACT [EMAPA:29663] synonym: "outer stripe of renal medulla" EXACT [FMA:76662] -synonym: "stria externa medullae renalis" EXACT LATIN [FMA:76662, FMA:TA] +synonym: "stria externa medullae renalis" EXACT OMO:0003011 [FMA:76662, FMA:TA] xref: EMAPA:29663 xref: FMA:76662 xref: MA:0002629 @@ -210353,7 +210689,7 @@ synonym: "muscular coat of urethra" EXACT [FMA:76909] synonym: "muscular layer of urethra" EXACT [FMA:76909] synonym: "smooth muscle of urethra" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of urethra" EXACT [OBOL:automatic] -synonym: "tunica muscularis urethrae" EXACT LATIN [FMA:TA] +synonym: "tunica muscularis urethrae" EXACT OMO:0003011 [FMA:TA] synonym: "urethra smooth muscle tissue" EXACT [OBOL:automatic] synonym: "urethral smooth muscle" RELATED [MA:0001691] xref: EMAPA:36630 @@ -210488,7 +210824,7 @@ synonym: "muscular coat of ductus deferens" EXACT [FMA:19239] synonym: "muscular layer of ductus deferens" EXACT [FMA:19239] synonym: "muscularis of vas deferens" EXACT [FMA:19239] synonym: "tunica muscularis (ductus deferens)" EXACT [FMA:19239] -synonym: "tunica muscularis ductus deferentis" EXACT LATIN [FMA:19239, FMA:TA] +synonym: "tunica muscularis ductus deferentis" EXACT OMO:0003011 [FMA:19239, FMA:TA] xref: EMAPA:29270 xref: FMA:19239 xref: MA:0001750 @@ -211014,7 +211350,7 @@ synonym: "smooth muscle of prostate" EXACT [OBOL:automatic] synonym: "smooth muscle of prostate gland" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of prostate" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of prostate gland" EXACT [OBOL:automatic] -synonym: "substantia muscularis prostatae" EXACT LATIN [FMA:74245, FMA:TA] +synonym: "substantia muscularis prostatae" EXACT OMO:0003011 [FMA:74245, FMA:TA] xref: BTO:0003159 xref: EMAPA:35713 xref: FMA:74245 @@ -211320,6 +211656,7 @@ id: UBERON:0004256 name: hindlimb zeugopod muscle namespace: uberon def: "Any muscle organ that is part of a hindlimb zeugopod (lower leg) [Automatically generated definition]." [OBOL:automatic] +subset: human_reference_atlas subset: pheno_slim synonym: "calf muscle" RELATED [OBOL:automatic] synonym: "lower leg muscle" EXACT [MA:0000678] @@ -211332,6 +211669,7 @@ is_a: UBERON:0001383 ! muscle of leg intersection_of: UBERON:0014892 ! skeletal muscle organ, vertebrate intersection_of: part_of UBERON:0003823 ! hindlimb zeugopod relationship: part_of UBERON:0006067 {source="prolog"} ! musculature of hindlimb zeugopod +relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens property_value: editor_note "the FMA class 'muscle of leg' belongs here, do not move[cjm]" xsd:string property_value: UBPROP:0000013 "See notes on UBERON:0000978 for possible terminological confusion over term 'leg'" xsd:string @@ -211746,15 +212084,15 @@ id: UBERON:0004292 name: cardiac skeleton namespace: uberon def: "Dense connective tissue that separates the atria from the ventricles and provides physical support for the heart." [GO:0003204, Wikipedia:Cardiac_skeleton] -synonym: "anulus fibrosus dexter cordis" RELATED LATIN [Wikipedia:Cardiac_skeleton] -synonym: "anulus fibrosus sinister cordis" RELATED LATIN [Wikipedia:Cardiac_skeleton] +synonym: "anulus fibrosus dexter cordis" RELATED OMO:0003011 [Wikipedia:Cardiac_skeleton] +synonym: "anulus fibrosus sinister cordis" RELATED OMO:0003011 [Wikipedia:Cardiac_skeleton] synonym: "cardiac fibrous skeleton" EXACT [EMAPA:36645] synonym: "fibrous skeleton of heart" EXACT [] synonym: "heart fibrous skeleton" EXACT [GO:0003204] synonym: "skeleton of heart" EXACT [FMA:9496] -synonym: "trigona fibrosa" RELATED LATIN [Wikipedia:Cardiac_skeleton] -synonym: "trigonum fibrosum dextrum cordis" RELATED LATIN [Wikipedia:Cardiac_skeleton] -synonym: "trigonum fibrosum sinistrum cordis" RELATED LATIN [Wikipedia:Cardiac_skeleton] +synonym: "trigona fibrosa" RELATED OMO:0003011 [Wikipedia:Cardiac_skeleton] +synonym: "trigonum fibrosum dextrum cordis" RELATED OMO:0003011 [Wikipedia:Cardiac_skeleton] +synonym: "trigonum fibrosum sinistrum cordis" RELATED OMO:0003011 [Wikipedia:Cardiac_skeleton] xref: EMAPA:36645 xref: FMA:9496 xref: Wikipedia:Cardiac_skeleton @@ -211856,7 +212194,7 @@ namespace: uberon def: "Distal-most phalanx within a digit." [http://orcid.org/0000-0002-6601-2165, https://github.com/obophenotype/uberon/issues/120] subset: pheno_slim synonym: "phalanx distalis" EXACT [Wikipedia:Distal_phalanges] -synonym: "phalanx distalis" RELATED LATIN [Wikipedia:Distal_phalanges] +synonym: "phalanx distalis" RELATED OMO:0003011 [Wikipedia:Distal_phalanges] synonym: "terminal phalanx" EXACT [AAO:0010676] synonym: "ungual phalanx" EXACT [http://www.medilexicon.com/medicaldictionary.php?t=67679] xref: AAO:0010676 @@ -211960,7 +212298,7 @@ xref: EHDAA2:0001525 xref: EHDAA:185 xref: EMAPA:16072 xref: FMA:293110 -xref: MESH:D054240 +xref: MESH:D054240 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: NCIT:C28402 xref: SCTID:361438007 xref: UMLS:C0033153 {source="ncithesaurus:Primitive_Streak"} @@ -212006,7 +212344,7 @@ namespace: uberon def: "An outgrowth on the lateral trunk of the embryo that develops into a limb. The limb bud is divided into ectoderm and mesenchyme[cjm, modified from MP]." [https://orcid.org/0000-0002-6601-2165, ISBN:9780878932504, MP:0005650, Wikipedia:Limb_bud] comment: developmentally_induced_by Fgf10, capable of initiating limb forming interactions between endoderm and mesoderm subset: pheno_slim -synonym: "gemmae membrorum" RELATED LATIN [Wikipedia:Limb_bud] +synonym: "gemmae membrorum" RELATED OMO:0003011 [Wikipedia:Limb_bud] synonym: "limb buds" EXACT OMO:0003004 [] synonym: "limbbud" EXACT [GO:0060174] xref: AAO:0010375 @@ -212047,7 +212385,7 @@ def: "Multilayered ectodermal region at the distal tip of a limb or fin bud nece subset: pheno_slim synonym: "AER" RELATED [MP:0001676] synonym: "apical epidermal ridge" EXACT [XAO:0004121] -synonym: "crista ectodermalis apicalis" RELATED LATIN [Wikipedia:Apical_ectodermal_ridge] +synonym: "crista ectodermalis apicalis" RELATED OMO:0003011 [Wikipedia:Apical_ectodermal_ridge] xref: AAO:0010760 xref: EMAPA:32744 xref: NCIT:C34109 @@ -212100,7 +212438,7 @@ subset: vertebrate_core synonym: "1st arch" RELATED [EHDAA2:0000006] synonym: "1st pharyngeal arch" EXACT [] synonym: "1st visceral arch" RELATED [VHOG:0000296] -synonym: "arcus pharyngeus primus" RELATED LATIN [Wikipedia:First_pharyngeal_arch] +synonym: "arcus pharyngeus primus" RELATED OMO:0003011 [Wikipedia:First_pharyngeal_arch] synonym: "branchial arch 1" EXACT SENSU [] synonym: "first branchial arch" EXACT SENSU [] synonym: "first pharyngeal arch" EXACT [] @@ -212139,11 +212477,11 @@ subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "a. arcuum pharyngeorum" RELATED LATIN [Wikipedia:Aortic_arches] +synonym: "a. arcuum pharyngeorum" RELATED OMO:0003011 [Wikipedia:Aortic_arches] synonym: "aortic arch" EXACT [ZFA:0005004] synonym: "aortic arch artery" RELATED [EMAPA:16684] synonym: "aortic arches" EXACT OMO:0003004 [ZFA:0005004] -synonym: "arteriae arcuum pharyngeorum" RELATED LATIN [Wikipedia:Aortic_arches] +synonym: "arteriae arcuum pharyngeorum" RELATED OMO:0003011 [Wikipedia:Aortic_arches] synonym: "branchial aortic arches" EXACT OMO:0003004 [ZFIN:ZDB-PUB-080512-6] synonym: "branchial aortic arches" RELATED OMO:0003004 [ZFA:0005004, ZFIN:ZDB-PUB-080512-6] synonym: "branchial arch artery" EXACT [EMAPA:16684] @@ -212219,7 +212557,7 @@ subset: vertebrate_core synonym: "Descemet membrane" EXACT [] synonym: "Descemet's posterior elastic lamina" EXACT [FMA:58309] synonym: "lamina limitans posterior" EXACT [FMA:58309] -synonym: "lamina limitans posterior corneae" EXACT LATIN [FMA:58309, FMA:TA] +synonym: "lamina limitans posterior corneae" EXACT OMO:0003011 [FMA:58309, FMA:TA] synonym: "posterior limiting lamina" EXACT [MA:0001246] synonym: "posterior limiting lamina of cornea" EXACT [FMA:58309] synonym: "posterior limiting membrane" EXACT [ZFA:0001686] @@ -212263,8 +212601,8 @@ synonym: "Bowman's anterior elastic lamina" EXACT [FMA:58273] synonym: "Bowman's layer" EXACT [FMA:58273] synonym: "Bowman's membrane" EXACT [FMA:58273] synonym: "lamina limitans anterior (cornea)" EXACT [FMA:58273] -synonym: "lamina limitans anterior corneae" EXACT LATIN [FMA:58273, FMA:TA] -synonym: "Reichert's membrane" RELATED DUBIOUS [http://sourceforge.net/tracker/?func=detail&aid=2956371&group_id=76834&atid=974957] +synonym: "lamina limitans anterior corneae" EXACT OMO:0003011 [FMA:58273, FMA:TA] +synonym: "Reichert's membrane" RELATED OMO:0003002 [http://sourceforge.net/tracker/?func=detail&aid=2956371&group_id=76834&atid=974957] xref: FMA:58273 xref: MA:0001240 xref: NCIT:C32226 @@ -212540,7 +212878,7 @@ namespace: uberon def: "A proximal epiphysis that is part of a phalanx of manus [Automatically generated definition]." [OBOL:automatic] synonym: "basal epiphysis of phalanx of finger" EXACT [FMA:226482] synonym: "base of phalanx of finger" EXACT [FMA:226482] -synonym: "basis phalangis manus" EXACT LATIN [FMA:226482, FMA:TA] +synonym: "basis phalangis manus" EXACT OMO:0003011 [FMA:226482, FMA:TA] synonym: "proximal epiphysis of phalanx of finger" EXACT [] synonym: "proximal epiphysis of phalanx of hand" RELATED [FMA:226482] xref: FMA:226482 @@ -212556,7 +212894,7 @@ name: proximal epiphysis of metatarsal bone namespace: uberon def: "A proximal epiphysis that is part of a metatarsal bone [Automatically generated definition]." [OBOL:automatic] synonym: "base of metatarsal bone" EXACT [FMA:33817] -synonym: "basis ossis metatarsi" EXACT LATIN [FMA:33817, FMA:TA] +synonym: "basis ossis metatarsi" EXACT OMO:0003011 [FMA:33817, FMA:TA] synonym: "proximal end of metatarsal bone" EXACT [FMA:33817] synonym: "upper end of metatarsal bone" EXACT [FMA:33817] xref: FMA:33817 @@ -212572,7 +212910,7 @@ name: proximal epiphysis of metacarpal bone namespace: uberon def: "A proximal epiphysis that is part of a metacarpal bone [Automatically generated definition]." [OBOL:automatic] synonym: "base of metacarpal bone" EXACT [FMA:33795] -synonym: "basis ossis metacarpi" EXACT LATIN [FMA:33795, FMA:TA] +synonym: "basis ossis metacarpi" EXACT OMO:0003011 [FMA:33795, FMA:TA] synonym: "metacarpal bone base" EXACT [FMA:33795] synonym: "proximal end of metacarpal bone" EXACT [FMA:33795] synonym: "upper end of metacarpal bone" EXACT [FMA:33795] @@ -212661,7 +212999,7 @@ alt_id: UBERON:0001462 def: "A mesopodium that is part of a manus. Includes as parts the carpal skeleton and associated tissues[cjm]. The anatomical region surrounding the carpus including the distal parts of the bones of the forearm and the proximal parts of the metacarpus or five metacarpal bones and the series of joints between these bones, thus referred to as wrist joints. This region also includes the carpal tunnel, the anatomical snuff box, the flexor retinaculum, and the extensor retinaculum[WP,unvetted]." [https://orcid.org/0000-0002-6601-2165, Wikipedia:Wrist] subset: pheno_slim subset: uberon_slim -synonym: "articulatio radiocarpea" RELATED LATIN [Wikipedia:Wrist] +synonym: "articulatio radiocarpea" RELATED OMO:0003011 [Wikipedia:Wrist] synonym: "carpal limb segment" EXACT [] synonym: "carpal segment" EXACT [] synonym: "carpus" RELATED INCONSISTENT [] @@ -212670,7 +213008,7 @@ synonym: "fore basipodium" EXACT [MA:th] synonym: "fore mesopodium" EXACT [MA:th] synonym: "hand mesopodium" EXACT [] synonym: "manus mesopodium" EXACT [] -synonym: "regio carpalis" EXACT LATIN [FMA:24922, FMA:TA] +synonym: "regio carpalis" EXACT OMO:0003011 [FMA:24922, FMA:TA] synonym: "wrist" EXACT [MA:0000039] synonym: "wrist region" EXACT [] xref: EHDAA2:0000218 @@ -212736,7 +213074,7 @@ subset: pheno_slim subset: uberon_slim synonym: "ankle" EXACT [MA:0000043] synonym: "ankle region" EXACT [] -synonym: "articulatio talocruralis" RELATED LATIN [Wikipedia:Ankle] +synonym: "articulatio talocruralis" RELATED OMO:0003011 [Wikipedia:Ankle] synonym: "hind basipodium" RELATED [MA:th] synonym: "hind mesopodium" RELATED [MA:th] synonym: "hock" RELATED SENSU [Wikipedia:Hock_(anatomy)] @@ -212804,7 +213142,7 @@ subset: non_informative synonym: "head musculature" EXACT [FMA:71287] synonym: "muscle group of head" EXACT [FMA:71287] synonym: "muscles of head" EXACT [FMA:71287] -synonym: "musculi capitis" EXACT LATIN [FMA:71287, FMA:TA] +synonym: "musculi capitis" EXACT OMO:0003011 [FMA:71287, FMA:TA] synonym: "set of muscles of head" EXACT [FMA:71287] xref: EMAPA:18171 xref: FMA:71287 @@ -212861,7 +213199,7 @@ def: "Any collection of muscles that is part of a thorax [Automatically generate subset: pheno_slim synonym: "muscle group of thorax" EXACT [FMA:71293] synonym: "muscles of thorax" EXACT [FMA:71293] -synonym: "musculi thoracis" EXACT LATIN [FMA:71293, FMA:TA] +synonym: "musculi thoracis" EXACT OMO:0003011 [FMA:71293, FMA:TA] synonym: "set of muscles of thorax" EXACT [FMA:71293] synonym: "thoracic musculature" EXACT [FMA:71293] xref: BTO:0000508 @@ -212882,8 +213220,8 @@ subset: pheno_slim synonym: "cervical muscles" EXACT [AAO:0000091] synonym: "muscle group of neck" EXACT [FMA:71290] synonym: "muscles of neck" EXACT [FMA:71290] -synonym: "musculi cervicis" EXACT LATIN [FMA:71290, FMA:TA] -synonym: "musculi colli" EXACT LATIN [FMA:71290, FMA:TA] +synonym: "musculi cervicis" EXACT OMO:0003011 [FMA:71290, FMA:TA] +synonym: "musculi colli" EXACT OMO:0003011 [FMA:71290, FMA:TA] synonym: "neck musculature" EXACT [FMA:71290] synonym: "set of muscles of neck" EXACT [FMA:71290] xref: AAO:0000091 @@ -212942,7 +213280,7 @@ namespace: uberon def: "Any collection of muscles that is part of a back [Automatically generated definition]." [OBOL:automatic] synonym: "muscle group of back" EXACT [FMA:71291] synonym: "muscles of back" EXACT [FMA:71291] -synonym: "musculi dorsi" EXACT LATIN [FMA:71291, FMA:TA] +synonym: "musculi dorsi" EXACT OMO:0003011 [FMA:71291, FMA:TA] synonym: "set of muscles of back" EXACT [FMA:71291] xref: FMA:71291 is_a: UBERON:0001015 ! musculature @@ -213005,7 +213343,7 @@ subset: pheno_slim synonym: "entire facial musculature" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "facial muscles" EXACT [FMA:71288] synonym: "muscle group of face" EXACT [FMA:71288] -synonym: "musculi faciei" EXACT LATIN [FMA:71288, FMA:TA] +synonym: "musculi faciei" EXACT OMO:0003011 [FMA:71288, FMA:TA] synonym: "set of facial muscles" RELATED [FMA:71288] synonym: "set of muscles of face" RELATED [FMA:71288] xref: FMA:71288 @@ -213447,7 +213785,7 @@ synonym: "papilla" NARROW [] synonym: "process" BROAD [VSAO:0000180] synonym: "process of organ" NARROW [] synonym: "processes" NARROW OMO:0003004 [VSAO:0000180] -synonym: "processus" EXACT LATIN [FMA:67601, FMA:TA] +synonym: "processus" EXACT OMO:0003011 [FMA:67601, FMA:TA] synonym: "projection" EXACT [] synonym: "projection" NARROW [VSAO:0000180] synonym: "projections" NARROW OMO:0003004 [VSAO:0000180] @@ -213592,7 +213930,7 @@ synonym: "lymphatic vasculature" EXACT [] synonym: "lymphatic vessel network" EXACT [] synonym: "lymphatic vessels set" EXACT [FMA:63815] synonym: "set of lymphatic vessels" EXACT [] -synonym: "trunci et ductus lymphatici" EXACT LATIN [FMA:63815, FMA:TA] +synonym: "trunci et ductus lymphatici" EXACT OMO:0003011 [FMA:63815, FMA:TA] xref: FMA:63815 xref: TAO:0005105 xref: ZFA:0005105 @@ -213744,7 +214082,7 @@ def: "The thick circular layer of smooth gastric musculature encircling the gast subset: pheno_slim synonym: "cardiac sphincter" EXACT [MA:0002951, MP:0010153] synonym: "cardiac sphincter" RELATED [Wikipedia:Cardia] -synonym: "constrictor cardiae" RELATED LATIN [MP:0010153] +synonym: "constrictor cardiae" RELATED OMO:0003011 [MP:0010153] synonym: "esophageal sphincter" RELATED [Wikipedia:Cardia] synonym: "esophageal sphincter%2c lower" RELATED [Wikipedia:Cardia] synonym: "esophageal-cardiac junction" RELATED [Wikipedia:Cardia] @@ -213763,6 +214101,7 @@ xref: EMAPA:18267 xref: FMA:14915 xref: galen:LowerEsophagealSphincter xref: MA:0002951 +xref: MESH:D049630 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} xref: NCIT:C33009 xref: SCTID:267809009 xref: UMLS:C0227192 {source="ncithesaurus:Lower_Esophageal_Sphincter"} @@ -213933,7 +214272,7 @@ synonym: "otic region" RELATED [] synonym: "periotic" RELATED [] synonym: "periotic capsule" RELATED [VHOG:0000854] xref: AAO:0010143 -xref: BTO:0005981 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: BTO:0005981 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: SCTID:361515007 xref: VHOG:0000854 is_a: UBERON:0010363 ! endochondral element @@ -213952,6 +214291,7 @@ id: UBERON:0004638 name: blood vessel endothelium namespace: uberon def: "An endothelium that lines the blood vasculature. Other endothelia may line lymph vessels, the heart." [https://orcid.org/0000-0002-6601-2165] +subset: human_reference_atlas subset: pheno_slim subset: vertebrate_core xref: BTO:0000766 @@ -213966,6 +214306,7 @@ is_a: UBERON:0004852 ! cardiovascular system endothelium intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:0001981 ! blood vessel relationship: part_of UBERON:0001981 ! blood vessel +relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: UBERON:0004639 @@ -213978,8 +214319,8 @@ subset: vertebrate_core synonym: "afferent arteriole" EXACT [MA:0002579] synonym: "afferent glomerular arteriole" EXACT [ZFA:0005307] synonym: "afferent glomerular arteriole of kidney" EXACT [FMA:77042] -synonym: "arteriola glomerularis afferens" RELATED LATIN [Wikipedia:Afferent_arterioles] -synonym: "arteriola glomerularis afferens renis" EXACT LATIN [FMA:77042, FMA:TA] +synonym: "arteriola glomerularis afferens" RELATED OMO:0003011 [Wikipedia:Afferent_arterioles] +synonym: "arteriola glomerularis afferens renis" EXACT OMO:0003011 [FMA:77042, FMA:TA] synonym: "kidney afferent arteriole" EXACT [MP:0011312] xref: EMAPA:28230 xref: EMAPA:28266 @@ -214008,8 +214349,8 @@ def: "The blood vessels that convey blood from the glomerulocapillary network to subset: human_reference_atlas subset: pheno_slim subset: vertebrate_core -synonym: "arteriola glomerularis efferens capsulae renalis" RELATED LATIN [Wikipedia:Efferent_arteriole] -synonym: "arteriola glomerularis efferens renis" EXACT LATIN [FMA:77043, FMA:TA] +synonym: "arteriola glomerularis efferens capsulae renalis" RELATED OMO:0003011 [Wikipedia:Efferent_arteriole] +synonym: "arteriola glomerularis efferens renis" EXACT OMO:0003011 [FMA:77043, FMA:TA] synonym: "efferent arteriole" EXACT [MA:0002585] synonym: "efferent glomerular arteriole" EXACT [ZFA:0005308] synonym: "efferent glomerular arteriole of kidney" EXACT [FMA:77043] @@ -214038,14 +214379,14 @@ namespace: uberon def: "The connective tissue that surrounds the spleen." [MGI:cwg, MP:0002227] subset: human_reference_atlas subset: pheno_slim -synonym: "capsula splenica" EXACT LATIN [FMA:15849, FMA:TA] +synonym: "capsula splenica" EXACT OMO:0003011 [FMA:15849, FMA:TA] synonym: "capsule of spleen" EXACT [FMA:15849] synonym: "fibroelastic coat of spleen" EXACT [FMA:15849] synonym: "fibrous capsule of spleen" EXACT [FMA:15849] synonym: "Malpighian capsule" EXACT [FMA:15849] synonym: "splenic capsule" EXACT [FMA:15849] synonym: "tunica fibrosa (splen)(lien)" EXACT [FMA:15849] -synonym: "tunica fibrosa splenica" EXACT LATIN [FMA:15849, FMA:TA] +synonym: "tunica fibrosa splenica" EXACT OMO:0003011 [FMA:15849, FMA:TA] xref: EMAPA:35802 xref: FMA:15849 xref: MA:0000753 @@ -214135,8 +214476,8 @@ subset: pheno_slim synonym: "hepatic lobule" EXACT [FMA:14471] synonym: "lobules of liver" RELATED OMO:0003004 [Wikipedia:Lobules_of_liver] synonym: "lobuli hepatici" EXACT OMO:0003004 [] -synonym: "lobuli hepatis" RELATED LATIN [Wikipedia:Lobules_of_liver] -synonym: "lobulus hepaticus" EXACT LATIN [FMA:14471] +synonym: "lobuli hepatis" RELATED OMO:0003011 [Wikipedia:Lobules_of_liver] +synonym: "lobulus hepaticus" EXACT OMO:0003011 [FMA:14471] xref: EMAPA:35499 xref: FMA:14471 xref: MA:0002494 @@ -214172,7 +214513,7 @@ def: "The body or shaft of the humerus is almost cylindrical in the upper half o subset: pheno_slim synonym: "body of humerus" EXACT [FMA:13305] synonym: "body of the humerus" RELATED [Wikipedia:Body_of_humerus] -synonym: "corpus humeri" EXACT LATIN [FMA:13305, FMA:TA] +synonym: "corpus humeri" EXACT OMO:0003011 [FMA:13305, FMA:TA] synonym: "diaphysis of humerus" EXACT [FMA:13305] synonym: "humeral diaphysis" EXACT [FMA:13305] synonym: "medial humerus" RELATED [Wikipedia:Body_of_humerus] @@ -214232,7 +214573,7 @@ synonym: "muscle layer of seminal vesicle" EXACT [FMA:19404] synonym: "muscular coat of seminal gland" EXACT [FMA:19404] synonym: "muscular layer of seminal gland" EXACT [FMA:19404] synonym: "tunica muscularis (vesicula seminalis)" EXACT [FMA:19404] -synonym: "tunica muscularis glandulae vesiculosae" EXACT LATIN [FMA:19404, FMA:TA] +synonym: "tunica muscularis glandulae vesiculosae" EXACT OMO:0003011 [FMA:19404, FMA:TA] xref: EMAPA:29773 xref: FMA:19404 xref: MA:0002913 @@ -214257,7 +214598,7 @@ synonym: "membranous part of interventricular septum" EXACT [FMA:7135] synonym: "membranous portion of interventricular septum" EXACT [FMA:7135] synonym: "membranous septum" BROAD [GO:0003149] synonym: "pars membranacea (septi interventricularis)" EXACT [FMA:7135] -synonym: "pars membranacea septi interventricularis" EXACT LATIN [FMA:7135, FMA:TA] +synonym: "pars membranacea septi interventricularis" EXACT OMO:0003011 [FMA:7135, FMA:TA] synonym: "ventricle membranous septum" BROAD [VT:0000018] synonym: "ventricular membranous septum" BROAD [MP:0008823] xref: EHDAA2:0004596 @@ -214289,8 +214630,8 @@ synonym: "muscular part interventricular septum" EXACT [] synonym: "muscular part of interventricular septum" EXACT [FMA:7134] synonym: "muscular septum" BROAD [GO:0003150] synonym: "pars muscularis (septi interventricularis)" EXACT [FMA:7134] -synonym: "pars muscularis septi interventricularis" EXACT LATIN [FMA:7134, FMA:TA] -synonym: "septum membranaceum" EXACT LATIN [] +synonym: "pars muscularis septi interventricularis" EXACT OMO:0003011 [FMA:7134, FMA:TA] +synonym: "septum membranaceum" EXACT OMO:0003011 [] synonym: "ventricular muscular septum" EXACT [] xref: EHDAA2:0000885 xref: EHDAA:2607 @@ -214358,7 +214699,7 @@ name: trigeminal nerve root namespace: uberon def: "A nerve root that extends_fibers_into a trigeminal nerve." [OBOL:automatic] synonym: "descending trigeminal root" RELATED [TAO:0000192] -synonym: "radix descendens nervi trigemini" EXACT LATIN [ZFA:0000192] +synonym: "radix descendens nervi trigemini" EXACT OMO:0003011 [ZFA:0000192] synonym: "root of trigeminal nerve" EXACT [FMA:52610] synonym: "root of trigeminal V nerve" EXACT [Obol:cjm] synonym: "trigeminal nerve root" EXACT [BIRNLEX:1346] @@ -214388,7 +214729,7 @@ synonym: "facial nerve or its root" RELATED [BAMS:7n] synonym: "facial nerve root" EXACT [BIRNLEX:1513] synonym: "facial nerve/root" RELATED [BAMS:7n] synonym: "facial neural root" EXACT [FMA:53418] -synonym: "fibrae nervi facialis" EXACT LATIN [FMA:53418, FMA:TA] +synonym: "fibrae nervi facialis" EXACT OMO:0003011 [FMA:53418, FMA:TA] synonym: "root of facial nerve" EXACT [FMA:53418] xref: BAMS:7n xref: BAMS:7nf @@ -214412,7 +214753,7 @@ alt_id: UBERON:0022760 def: "A nerve root that extends_fibers_into a hypoglossal nerve." [OBOL:automatic] synonym: "central part of hypoglossal nerve" EXACT [FMA:72632] synonym: "central part of hypoglossal nerve" RELATED [BIRNLEX:1288] -synonym: "fibrae nervi hypoglossi" EXACT LATIN [FMA:72632, FMA:TA] +synonym: "fibrae nervi hypoglossi" EXACT OMO:0003011 [FMA:72632, FMA:TA] synonym: "hypoglossal nerve fiber bundle" EXACT HUMAN_PREFERRED [BIRNLEX:1288] synonym: "hypoglossal nerve fibers" EXACT [FMA:72632] synonym: "hypoglossal nerve fibers" RELATED [BIRNLEX:1288] @@ -214444,7 +214785,7 @@ def: "The molecular layer of the dentate gyrus that is bounded by the pial surfa synonym: "dentate gyrus molecular layer" EXACT [BIRNLEX:4127] synonym: "molecular layer of dentate gyrus" EXACT [FMA:83677] synonym: "molecular layer of the dentate gyrus" RELATED [BAMS:Mol] -synonym: "stratum moleculare gyri dentati" EXACT LATIN [FMA:83677, FMA:TA] +synonym: "stratum moleculare gyri dentati" EXACT OMO:0003011 [FMA:83677, FMA:TA] xref: BAMS:mo xref: BAMS:Mol xref: BIRNLEX:4127 @@ -214493,8 +214834,8 @@ namespace: uberon def: "The raphe nuclei are thin plates of cells in and immediately adjacent to the sagittal plane." [https://sourceforge.net/tracker/?func=detail&aid=3248146&group_id=36855&atid=440764, NLXANAT:20090205] comment: we treat NR obscurus, NR magnus etc as parts of the raphe nuclei. This is consistent with treatment in FMA, where the class is 'set of raphe nuclei' subset: vertebrate_core -synonym: "nuclei raphes" EXACT LATIN [FMA:84017, FMA:TA] -synonym: "nuclei raphes" RELATED LATIN [Wikipedia:Raphe_nuclei] +synonym: "nuclei raphes" EXACT OMO:0003011 [FMA:84017, FMA:TA] +synonym: "nuclei raphes" RELATED OMO:0003011 [Wikipedia:Raphe_nuclei] synonym: "raphe cluster" RELATED [Wikipedia:Raphe_nuclei] synonym: "raphe nuclei" EXACT [FMA:84017, NLXANAT:20090205] synonym: "raphe nuclei set" EXACT [FMA:84017] @@ -214525,7 +214866,7 @@ namespace: uberon def: "The costocervical trunk arises from the upper and back part of the subclavian artery, behind the scalenus anterior on the right side, and medial to that muscle on the left side. Passing backward, it splits into the deep cervical artery and the supreme intercostal artery (or the Highest intercostal artery), which descends behind the pleura in front of the necks of the first and second ribs, and anastomoses with the first aortic intercostal (3rd posterior intercostal artery). As it crosses the neck of the first rib it lies medial to the anterior division of the first thoracic nerve, and lateral to the first thoracic ganglion of the sympathetic trunk. In the first intercostal space, it gives off a branch which is distributed in a manner similar to the distribution of the aortic intercostals. The branch for the second intercostal space usually joins with one from the highest aortic intercostal artery. This branch is not constant, but is more commonly found on the right side; when absent, its place is supplied by an intercostal branch from the aorta. Each intercostal gives off a posterior branch which goes to the posterior vertebral muscles, and sends a small spinal branch through the corresponding intervertebral foramen to the medulla spinalis and its membranes. [WP,unvetted]." [Wikipedia:Costocervical_trunk] subset: human_reference_atlas synonym: "costocervical trunk" EXACT [FMA:10636] -synonym: "truncus costocervicalis" RELATED LATIN [Wikipedia:Costocervical_trunk] +synonym: "truncus costocervicalis" RELATED OMO:0003011 [Wikipedia:Costocervical_trunk] synonym: "trunk of costocervical artery" EXACT [FMA:10636] xref: EMAPA:37496 {source="MA:th"} xref: FMA:10636 @@ -214685,7 +215026,7 @@ subset: vertebrate_core synonym: "dorsal thalamus" EXACT [FMA:62007] synonym: "dorsal thalamus (Anthoney)" EXACT [FMA:62007] synonym: "dorsal tier of thalamus" RELATED [DMBA:DTTh] -synonym: "thalamus dorsalis" EXACT LATIN [BTO:0001365, Wikipedia:Thalamus] +synonym: "thalamus dorsalis" EXACT OMO:0003011 [BTO:0001365, Wikipedia:Thalamus] synonym: "thalamus proper" EXACT [PMCID:PMC3345571] synonym: "thalamus, pars dorsalis" EXACT [ZFA:0000653] xref: BAMS:DOR @@ -214934,7 +215275,7 @@ synonym: "arcuate vein" BROAD [MA:0002593] synonym: "arcuate vein of kidney" EXACT [MP:0011325] synonym: "arcuate veins" RELATED [Wikipedia:Arcuate_vein] synonym: "renal arcuate vein" EXACT [MP:0011325] -synonym: "venae arcuatae renis" EXACT LATIN [Wikipedia:Arcuate_vein] +synonym: "venae arcuatae renis" EXACT OMO:0003011 [Wikipedia:Arcuate_vein] xref: EMAPA:28221 xref: FMA:272193 xref: FMA:321527 @@ -214976,8 +215317,8 @@ namespace: uberon def: "The branches of the arcuate arteries of the kidney that radiate outward throught the renal columns and supply the glomeruli[MP]. The first set of renal bloodvessels, the interlobular arteries (or cortical radiate arteries, or cortical radial arteries), are given off at right angles from the side of the arcuate arteries looking toward the cortical substance, and pass directly outward between the medullary rays to reach the fibrous tunic, where they end in the capillary network of this part. These vessels do not anastomose with each other, but form what are called end-arteries. In their outward course they give off lateral branches; these are the afferent vessels for the renal corpuscles; they enter the capsule, and end in the glomerulus. From each tuft the corresponding efferent vessel arises, and, having made its egress from the capsule near to the point where the afferent vessel enters, breaks up into a number of branches, which form a dense plexus within Bowman's capsule." [MP:0011316, Wikipedia:Interlobular_arteries] subset: human_reference_atlas subset: pheno_slim -synonym: "arteriae corticales radiatae" RELATED LATIN [Wikipedia:Interlobular_arteries] -synonym: "arteriae interlobulares renis" RELATED LATIN [Wikipedia:Interlobular_arteries] +synonym: "arteriae corticales radiatae" RELATED OMO:0003011 [Wikipedia:Interlobular_arteries] +synonym: "arteriae interlobulares renis" RELATED OMO:0003011 [Wikipedia:Interlobular_arteries] synonym: "cortical radial arteries" RELATED [Wikipedia:Interlobular_arteries] synonym: "interlobular" RELATED [Wikipedia:Interlobular_arteries] synonym: "interlobular renal artery" EXACT [FMA:70498] @@ -215003,11 +215344,11 @@ namespace: uberon def: "The subdivision of the laminated olfactory cortex with only three main layers that receive monosynaptic input from the olfactory bulb via the lateral olfactory tract; it is located bilaterally in the ventrolateral forebrain and is commonly divided into anterior and posterior regions." [MP:0010009, PMID:17714095] subset: human_reference_atlas subset: pheno_slim -synonym: "area prepiriformis" RELATED LATIN [NeuroNames:165] -synonym: "cortex piriformis" EXACT LATIN [Wikipedia:Piriform_cortex] -synonym: "eupalaeocortex" RELATED LATIN [NeuroNames:165] +synonym: "area prepiriformis" RELATED OMO:0003011 [NeuroNames:165] +synonym: "cortex piriformis" EXACT OMO:0003011 [Wikipedia:Piriform_cortex] +synonym: "eupalaeocortex" RELATED OMO:0003011 [NeuroNames:165] synonym: "olfactory pallium" RELATED [ISBN:0471888893] -synonym: "palaeocortex II" RELATED LATIN [NeuroNames:165] +synonym: "palaeocortex II" RELATED OMO:0003011 [NeuroNames:165] synonym: "paleopallium" RELATED [Wikipedia:Piriform_cortex] synonym: "piriform area" RELATED [BTO:0002651, MA:0000978] synonym: "piriform lobe" RELATED [BTO:0002651] @@ -215015,7 +215356,7 @@ synonym: "primary olfactory areas" EXACT [BIRNLEX:2706] synonym: "primary olfactory cortex" RELATED INCONSISTENT [Wikipedia:Piriform_cortex] synonym: "pyriform cortex" RELATED [Wikipedia:Piriform_cortex] synonym: "pyriform lobe" RELATED [Wikipedia:Piriform_cortex] -synonym: "regio praepiriformis" RELATED LATIN [NeuroNames:165] +synonym: "regio praepiriformis" RELATED OMO:0003011 [NeuroNames:165] xref: BAMS:PIR xref: BAMS:Pir xref: BIRNLEX:1097 @@ -215049,15 +215390,15 @@ subset: human_reference_atlas subset: pheno_slim synonym: "arteria recta" RELATED [Wikipedia:Vasa_recta] synonym: "arteriae rectae" RELATED [Wikipedia:Vasa_recta] -synonym: "arteriolae rectae renis" EXACT LATIN [FMA:72006, FMA:TA] -synonym: "arteriolae rectae renis" RELATED LATIN [Wikipedia:Vasa_recta] +synonym: "arteriolae rectae renis" EXACT OMO:0003011 [FMA:72006, FMA:TA] +synonym: "arteriolae rectae renis" RELATED OMO:0003011 [Wikipedia:Vasa_recta] synonym: "arteriolae recti" RELATED [Wikipedia:Vasa_recta] synonym: "kidney vasa recta" EXACT [MP:0011324] synonym: "renal medullary capillary" EXACT [EMAPA:30043] synonym: "set of straight arterioles of kidney" EXACT [FMA:72006] synonym: "straight arterioles of kidney" EXACT [FMA:72006] synonym: "vasa recta of kidney" EXACT [FMA:72006] -synonym: "vasa recta renis" EXACT LATIN [FMA:72006, FMA:TA] +synonym: "vasa recta renis" EXACT OMO:0003011 [FMA:72006, FMA:TA] synonym: "vasa rectae" RELATED [Wikipedia:Vasa_recta] xref: EMAPA:30043 xref: FMA:72006 @@ -215179,7 +215520,7 @@ synonym: "trilaminar disk" RELATED [https://orcid.org/0000-0002-6601-2165] synonym: "trilaminar germ" RELATED [https://orcid.org/0000-0002-6601-2165] xref: BILA:0000060 xref: BTO:0001403 -xref: FBbt:00005317 +xref: FBbt:00005317 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:293108 xref: GAID:1302 xref: MESH:D005775 @@ -215749,7 +216090,7 @@ synonym: "serous coat of gallbladder" EXACT [FMA:14659] synonym: "serous membrane of gall bladder" EXACT [OBOL:automatic] synonym: "serous membrane of gallbladder" EXACT [OBOL:automatic] synonym: "tunica serosa (vesica biliaris)" EXACT [FMA:14659] -synonym: "tunica serosa vesicae biliaris" EXACT LATIN [FMA:14659, FMA:TA] +synonym: "tunica serosa vesicae biliaris" EXACT OMO:0003011 [FMA:14659, FMA:TA] xref: EMAPA:35372 xref: FMA:14659 xref: MA:0001634 @@ -216945,7 +217286,7 @@ synonym: "retinal blood vessels set" EXACT [FMA:76552] synonym: "retinal vasculature" EXACT [OBOL:automatic] synonym: "set of blood vessels of retina" EXACT [OBOL:automatic] synonym: "set of retinal blood vessels" EXACT [FMA:76552] -synonym: "vasa sanguinea retinae" EXACT LATIN [FMA:76552, FMA:TA] +synonym: "vasa sanguinea retinae" EXACT OMO:0003011 [FMA:76552, FMA:TA] xref: FMA:76552 xref: MESH:D012171 xref: XAO:0004153 @@ -217069,7 +217410,7 @@ name: nephrogenic cord namespace: uberon def: "A portion of the urogenital ridge which is the source of much of the urinary system[WP]." [Wikipedia:Nephrogenic_cord] comment: part_of or develops_from urogenital ridge? -synonym: "chorda nephrogenica" RELATED LATIN [Wikipedia:Nephrogenic_cord] +synonym: "chorda nephrogenica" RELATED OMO:0003011 [Wikipedia:Nephrogenic_cord] xref: FMA:72168 xref: NCIT:C34219 xref: SCTID:361405003 @@ -217274,7 +217615,7 @@ synonym: "optic nerve" BROAD [BTO:0000966] synonym: "optic nerve (generic)" EXACT [] xref: BTO:0000966 xref: EV:0100351 -xref: FBbt:00001956 +xref: FBbt:00001956 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: TADS:0000232 is_a: UBERON:0000122 ! neuron projection bundle intersection_of: UBERON:0000122 ! neuron projection bundle @@ -217292,7 +217633,7 @@ namespace: uberon def: "Anatomical structure that connects two or more adjacent skeletal elements or hardened body parts." [http://orcid.org/0000-0002-6601-2165] subset: grouping_class synonym: "joint" NARROW [] -xref: FBbt:00005811 +xref: FBbt:00005811 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0034921 ! multi organ part structure relationship: part_of UBERON:0004770 ! articular system @@ -217420,11 +217761,11 @@ namespace: uberon def: "A dilation of the duodenal papilla that is the opening of the juncture of the common bile duct and the main pancreatic duct." [Wikipedia:Ampulla_of_Vater] subset: human_reference_atlas subset: vertebrate_core -synonym: "ampulla biliaropancreatica" EXACT LATIN [FMA:15076, FMA:TA] -synonym: "ampulla hepatopancreatica" RELATED LATIN [Wikipedia:Ampulla_of_Vater] +synonym: "ampulla biliaropancreatica" EXACT OMO:0003011 [FMA:15076, FMA:TA] +synonym: "ampulla hepatopancreatica" RELATED OMO:0003011 [Wikipedia:Ampulla_of_Vater] synonym: "ampulla of bile duct" EXACT [FMA:15076] synonym: "ampulla of Vater" EXACT [] -synonym: "ampulla Vaterii" RELATED LATIN [Wikipedia:Ampulla_of_Vater] +synonym: "ampulla Vaterii" RELATED OMO:0003011 [Wikipedia:Ampulla_of_Vater] synonym: "biliaropancreatic ampulla" EXACT [] synonym: "papilla duodeni major" RELATED [ZFA:0005167] synonym: "papilla Vateri" EXACT [ZFA:0005167] @@ -217456,7 +217797,7 @@ name: duodenal papilla namespace: uberon def: "One of the two small elevations on the mucosa of the duodenum, the major at the entrance of the conjoined pancreatic and common bile ducts and the minor at the entrance of the accessory pancreatic duct." [http://medical-dictionary.thefreedictionary.com/duodenal+papilla] synonym: "papilla duodenalis" EXACT [] -synonym: "papilla duodeni" RELATED LATIN [Wikipedia:Major_duodenal_papilla] +synonym: "papilla duodeni" RELATED OMO:0003011 [Wikipedia:Major_duodenal_papilla] synonym: "papilla of duodenum" EXACT [] xref: EMAPA:18662 xref: FMA:15953 @@ -217476,7 +217817,7 @@ def: "Muscular valve that controls the flow of digestive juices (bile and pancre subset: human_reference_atlas synonym: "hepatopancreatic ampullary sphincter" EXACT [FMA:15077] synonym: "musculus sphincter ampullae" EXACT [FMA:15077] -synonym: "musculus sphincter ampullae hepatopancreatica" EXACT LATIN [FMA:15077, FMA:TA] +synonym: "musculus sphincter ampullae hepatopancreatica" EXACT OMO:0003011 [FMA:15077, FMA:TA] synonym: "Oddi's sphincter" EXACT [] synonym: "sphincter of ampulla of vater" EXACT [FMA:15077] synonym: "sphincter of Oddi" EXACT [] @@ -217540,7 +217881,7 @@ synonym: "gut section" RELATED [FBbt:00100315] synonym: "intestinal tract" RELATED [] synonym: "segment of intestinal tract" RELATED [] synonym: "subdivision of alimentary system" RELATED [FMA:71131] -xref: FBbt:00100315 +xref: FBbt:00100315 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:71131 is_a: UBERON:0013522 ! subdivision of tube intersection_of: UBERON:0013522 ! subdivision of tube @@ -217571,8 +217912,8 @@ synonym: "pharyngobasilar fascia" RELATED [] synonym: "pharynx submucosa" EXACT [OBOL:automatic] synonym: "submucous coat of pharynx" RELATED [BTO:0002113] synonym: "submucous layer of pharynx" RELATED [BTO:0002113] -synonym: "tela submucosa pharyngea" EXACT LATIN [FMA:75144, FMA:TA] -synonym: "tela submucosa pharyngis" EXACT LATIN [BTO:0002113] +synonym: "tela submucosa pharyngea" EXACT OMO:0003011 [FMA:75144, FMA:TA] +synonym: "tela submucosa pharyngis" EXACT OMO:0003011 [BTO:0002113] xref: BTO:0002113 xref: FMA:75144 xref: SCTID:19594009 @@ -217851,8 +218192,8 @@ subset: human_reference_atlas synonym: "bladder submucosa" EXACT [OBOL:automatic] synonym: "submucosa of bladder" EXACT [OBOL:automatic] synonym: "submucous layer of urinary bladder" RELATED [BTO:0002117] -synonym: "tela submucosa (vesica urinaria)" EXACT LATIN [FMA:15929, FMA:TA] -synonym: "tela submucosa vesicae" EXACT LATIN [FMA:15929, FMA:TA] +synonym: "tela submucosa (vesica urinaria)" EXACT OMO:0003011 [FMA:15929, FMA:TA] +synonym: "tela submucosa vesicae" EXACT OMO:0003011 [FMA:15929, FMA:TA] synonym: "tela submucosa vesicae urinariae" EXACT [BTO:0002117] synonym: "urinary bladder submucosa" EXACT [OBOL:automatic] xref: BTO:0002117 @@ -217979,7 +218320,7 @@ synonym: "mucosal layer of ureter" EXACT [FMA:15894] synonym: "mucous membrane of ureter" EXACT [OBOL:automatic] synonym: "organ mucosa of ureter" EXACT [OBOL:automatic] synonym: "tunica mucosa (ureter)" EXACT [FMA:15894] -synonym: "tunica mucosa ureteris" EXACT LATIN [FMA:15894, FMA:TA] +synonym: "tunica mucosa ureteris" EXACT OMO:0003011 [FMA:15894, FMA:TA] synonym: "ureter mucosa" EXACT [OBOL:automatic] synonym: "ureter mucosa of organ" EXACT [OBOL:automatic] synonym: "ureter mucous membrane" EXACT [OBOL:automatic] @@ -218002,7 +218343,7 @@ def: "A mucosa that is part of a vagina [Automatically generated definition]." [ synonym: "mucosa of organ of vagina" EXACT [OBOL:automatic] synonym: "mucous membrane of vagina" EXACT [OBOL:automatic] synonym: "organ mucosa of vagina" EXACT [OBOL:automatic] -synonym: "tunica mucosa vaginae" EXACT LATIN [FMA:19975, FMA:TA] +synonym: "tunica mucosa vaginae" EXACT OMO:0003011 [FMA:19975, FMA:TA] synonym: "vagina mucosa" EXACT [OBOL:automatic] synonym: "vagina mucosa of organ" EXACT [OBOL:automatic] synonym: "vagina mucous membrane" EXACT [OBOL:automatic] @@ -218036,7 +218377,7 @@ synonym: "seminal vesicle mucosa" EXACT [OBOL:automatic] synonym: "seminal vesicle mucosa of organ" EXACT [OBOL:automatic] synonym: "seminal vesicle mucous membrane" EXACT [OBOL:automatic] synonym: "seminal vesicle organ mucosa" EXACT [OBOL:automatic] -synonym: "tunica mucosa glandulae vesiculosae" EXACT LATIN [FMA:19405, FMA:TA] +synonym: "tunica mucosa glandulae vesiculosae" EXACT OMO:0003011 [FMA:19405, FMA:TA] xref: FMA:19405 xref: SCTID:252260007 is_a: UBERON:0019042 ! reproductive system mucosa @@ -218101,7 +218442,7 @@ synonym: "sperm duct mucosa of organ" EXACT [OBOL:automatic] synonym: "sperm duct mucous membrane" EXACT [OBOL:automatic] synonym: "sperm duct organ mucosa" EXACT [OBOL:automatic] synonym: "tunica mucosa (ductus deferens)" EXACT [FMA:19240] -synonym: "tunica mucosa ductus deferentis" EXACT LATIN [FMA:19240, FMA:TA] +synonym: "tunica mucosa ductus deferentis" EXACT OMO:0003011 [FMA:19240, FMA:TA] synonym: "vas deferen mucosa" EXACT [OBOL:automatic] synonym: "vas deferen mucosa of organ" EXACT [OBOL:automatic] synonym: "vas deferen mucous membrane" EXACT [OBOL:automatic] @@ -218644,7 +218985,7 @@ synonym: "renal pelvis mucosa" EXACT [OBOL:automatic] synonym: "renal pelvis mucosa of organ" EXACT [OBOL:automatic] synonym: "renal pelvis mucous membrane" EXACT [OBOL:automatic] synonym: "renal pelvis organ mucosa" EXACT [OBOL:automatic] -synonym: "tunica mucosa pelvis renalis" EXACT LATIN [FMA:17931, FMA:TA] +synonym: "tunica mucosa pelvis renalis" EXACT OMO:0003011 [FMA:17931, FMA:TA] xref: FMA:17931 xref: SCTID:243482002 is_a: UBERON:0000344 ! mucosa @@ -218886,7 +219227,7 @@ synonym: "prostatic urethra mucosa of organ" EXACT [OBOL:automatic] synonym: "prostatic urethra mucous membrane" EXACT [OBOL:automatic] synonym: "prostatic urethra organ mucosa" EXACT [OBOL:automatic] synonym: "prostatic urethral mucosa" EXACT [FMA:77079] -synonym: "tunica mucosa urethrae prosticae" EXACT LATIN [FMA:77079, FMA:TA] +synonym: "tunica mucosa urethrae prosticae" EXACT OMO:0003011 [FMA:77079, FMA:TA] xref: FMA:77079 is_a: UBERON:0005013 ! mucosa of male urethra intersection_of: UBERON:0000344 ! mucosa @@ -218925,7 +219266,7 @@ synonym: "tongue mucosa" EXACT [OBOL:automatic] synonym: "tongue mucosa of organ" EXACT [OBOL:automatic] synonym: "tongue mucous membrane" EXACT [OBOL:automatic] synonym: "tongue organ mucosa" EXACT [OBOL:automatic] -synonym: "tunica mucosa linguae" EXACT LATIN [FMA:54807, FMA:TA] +synonym: "tunica mucosa linguae" EXACT OMO:0003011 [FMA:54807, FMA:TA] xref: EFO:0002553 xref: FMA:54807 xref: SCTID:362092002 @@ -218983,7 +219324,7 @@ synonym: "mucosa of organ of middle ear" EXACT [OBOL:automatic] synonym: "mucosa of tympanic cavity" EXACT [FMA:59663] synonym: "mucous membrane of middle ear" EXACT [OBOL:automatic] synonym: "organ mucosa of middle ear" EXACT [OBOL:automatic] -synonym: "tunica mucosa cavitatis tympanicae" EXACT LATIN [FMA:59663, FMA:TA] +synonym: "tunica mucosa cavitatis tympanicae" EXACT OMO:0003011 [FMA:59663, FMA:TA] xref: CALOHA:TS-0631 xref: FMA:59663 is_a: UBERON:0000344 ! mucosa @@ -219075,7 +219416,7 @@ synonym: "mucous membrane of gallbladder" EXACT [OBOL:automatic] synonym: "organ mucosa of gall bladder" EXACT [OBOL:automatic] synonym: "organ mucosa of gallbladder" EXACT [OBOL:automatic] synonym: "tunica mucosa (vesica biliaris)" EXACT [FMA:14662] -synonym: "tunica mucosa vesicae biliaris" EXACT LATIN [FMA:14662, FMA:TA] +synonym: "tunica mucosa vesicae biliaris" EXACT OMO:0003011 [FMA:14662, FMA:TA] xref: FMA:14662 xref: SCTID:362196002 is_a: UBERON:0000344 ! mucosa @@ -219262,7 +219603,7 @@ synonym: "mucous membrane of fallopian tube" EXACT [OBOL:automatic] synonym: "mucous membrane of uterine tube" EXACT [OBOL:automatic] synonym: "organ mucosa of fallopian tube" EXACT [OBOL:automatic] synonym: "organ mucosa of uterine tube" EXACT [OBOL:automatic] -synonym: "tunica mucosa tubae uterinae" EXACT LATIN [FMA:18319, FMA:TA] +synonym: "tunica mucosa tubae uterinae" EXACT OMO:0003011 [FMA:18319, FMA:TA] synonym: "uterine tubal mucosa" EXACT [FMA:18319] synonym: "uterine tube mucosa" EXACT [OBOL:automatic] synonym: "uterine tube mucosa of organ" EXACT [OBOL:automatic] @@ -219426,7 +219767,7 @@ property_value: UBPROP:0000001 "In front of the primitive streak two longitudina id: UBERON:0005064 name: left ventricular trabecular myocardium namespace: uberon -def: "." [GO:0003225] +def: "Missing definition for term UBERON:0005064. Please replace it using linked reference." [GO:0003225] is_a: UBERON:0004126 ! trabecular layer of ventricle intersection_of: UBERON:0004126 ! trabecular layer of ventricle intersection_of: part_of UBERON:0002084 ! heart left ventricle @@ -219436,7 +219777,7 @@ relationship: part_of UBERON:0003382 {source="GO"} ! cardiac muscle of left vent id: UBERON:0005066 name: right ventricular trabecular myocardium namespace: uberon -def: "." [GO:0003227] +def: "Missing definition for term UBERON:0005066. Please replace it using linked reference." [GO:0003227] is_a: UBERON:0004126 ! trabecular layer of ventricle intersection_of: UBERON:0004126 ! trabecular layer of ventricle intersection_of: part_of UBERON:0002080 ! heart right ventricle @@ -219642,7 +219983,7 @@ property_value: UBPROP:0000003 "Three major adaptations, or 'novel cardiac compo id: UBERON:0005095 name: kidney rudiment namespace: uberon -def: "." [GO:0072003] +def: "Missing definition for term UBERON:0005095. Please replace it using linked reference." [GO:0072003] synonym: "kidney anlage" RELATED [GOC:mtg_kidney_jan10] is_a: UBERON:0002050 ! embryonic structure relationship: develops_from UBERON:0007687 {source="GO"} ! kidney field @@ -219685,7 +220026,7 @@ def: "The connecting tubule is a tubular segment of the nephron; it connects the subset: human_reference_atlas synonym: "connecting tubule" EXACT [MA:0002610] synonym: "kidney connecting tubule" EXACT [MA:0002610] -synonym: "tubulus renalis arcuatus" RELATED LATIN [Wikipedia:Connecting_tubule] +synonym: "tubulus renalis arcuatus" RELATED OMO:0003011 [Wikipedia:Connecting_tubule] xref: BTO:0004539 xref: EMAPA:27758 xref: EMAPA:27790 @@ -220162,7 +220503,7 @@ synonym: "invertebrate tracheal system" EXACT [] synonym: "open tracheal system" EXACT [] synonym: "tracheal system" BROAD SENSU [FBbt:00005024] xref: BTO:0003870 -xref: FBbt:00005024 +xref: FBbt:00005024 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: SPD:0000427 xref: TADS:0000043 is_a: UBERON:0001004 ! respiratory system @@ -220224,7 +220565,7 @@ synonym: "multi-cell-component structure" EXACT [CARO:0001000] synonym: "multi-cell-part structure" EXACT [CARO:0001000] xref: AAO:0011000 xref: CARO:0001000 -xref: FBbt:00007060 +xref: FBbt:00007060 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:83115 is_a: UBERON:0000061 ! anatomical structure relationship: composed_primarily_of GO:0005575 ! cellular_component @@ -220281,8 +220622,8 @@ subset: pheno_slim synonym: "interlobular vein" EXACT [MA:0002594] synonym: "interlobular veins of kidney" RELATED [FMA:71634] synonym: "set of interlobular veins of kidney" RELATED [FMA:71634] -synonym: "venae interlobulares renis" EXACT LATIN [FMA:71634, FMA:TA] -synonym: "venae interlobulares renis" RELATED LATIN [Wikipedia:Interlobular_veins] +synonym: "venae interlobulares renis" EXACT OMO:0003011 [FMA:71634, FMA:TA] +synonym: "venae interlobulares renis" RELATED OMO:0003011 [Wikipedia:Interlobular_veins] xref: EMAPA:28218 xref: FMA:71634 xref: MA:0002594 @@ -220436,7 +220777,7 @@ subset: vertebrate_core synonym: "dental organ" EXACT [ZFA:0005138] synonym: "enamel organ" EXACT [MP:0010747] synonym: "odontogenic organ" RELATED [] -synonym: "organum enameleum" RELATED LATIN [Wikipedia:Enamel_organ] +synonym: "organum enameleum" RELATED OMO:0003011 [Wikipedia:Enamel_organ] xref: BTO:0001722 xref: CALOHA:TS-0271 xref: EMAPA:32888 @@ -220559,7 +220900,7 @@ name: deferent duct artery namespace: uberon def: "An artery in males that provides blood to the vas deferens. The artery usually arises from the anterior trunk of the superior vesical artery. It accompanies the vas deferens into the testis, where it anastomoses with the testicular artery. In this way it also supplies blood to the testis and epididymis. A small branch supplies the ureter[WP]." [Wikipedia:Artery_to_the_ductus_deferens] subset: human_reference_atlas -synonym: "arteria ductus deferentis" EXACT LATIN [Wikipedia:Artery_to_the_ductus_deferens] +synonym: "arteria ductus deferentis" EXACT OMO:0003011 [Wikipedia:Artery_to_the_ductus_deferens] synonym: "artery of ductus deferens" EXACT [FMA:18930] synonym: "ductus deferens artery" EXACT [FMA:18930] synonym: "vas deferens artery" EXACT [] @@ -221433,7 +221774,7 @@ synonym: "CNS ventricular system" EXACT [EHDAA2:0004362] synonym: "ventricle system" RELATED [Wikipedia:Ventricular_system] synonym: "ventricular system" EXACT [ZFA:0001261] synonym: "ventricular system of neuraxis" EXACT [FMA:242675] -synonym: "ventriculi cerebri" RELATED LATIN [Wikipedia:Ventricular_system] +synonym: "ventriculi cerebri" RELATED OMO:0003011 [Wikipedia:Ventricular_system] xref: EFO:0003650 xref: EHDAA2:0004362 xref: EV:0100306 @@ -221495,8 +221836,8 @@ synonym: "tela chorioidea fourth ventricle" EXACT [] synonym: "tela choroidea" BROAD [FMA:78493, FMA:TA] synonym: "tela choroidea fourth ventricle" EXACT [] synonym: "tela choroidea of fourth ventricle" EXACT [] -synonym: "tela choroidea ventriculi quarti" EXACT LATIN [FMA:78493, FMA:TA] -synonym: "tela choroidea ventriculi quarti" RELATED LATIN [Wikipedia:Tela_chorioidea_of_fourth_ventricle] +synonym: "tela choroidea ventriculi quarti" EXACT OMO:0003011 [FMA:78493, FMA:TA] +synonym: "tela choroidea ventriculi quarti" RELATED OMO:0003011 [Wikipedia:Tela_chorioidea_of_fourth_ventricle] xref: BAMS:tc4v xref: FMA:78493 xref: neuronames:639 @@ -221519,7 +221860,7 @@ subset: vertebrate_core synonym: "tela chorioidea of lateral ventricle" EXACT [] synonym: "tela chorioidea of telencephalic ventricle" EXACT [] synonym: "tela chorioidea telencephalic ventricle" EXACT [ZFA:0005160] -synonym: "tela choroidea (ventriculi lateralis)" EXACT LATIN [FMA:83712, FMA:TA] +synonym: "tela choroidea (ventriculi lateralis)" EXACT OMO:0003011 [FMA:83712, FMA:TA] synonym: "tela choroidea of lateral ventricle" EXACT [FMA:83712] synonym: "tela choroidea telencephalic ventricle" EXACT [] xref: BAMS:tclv @@ -221549,7 +221890,7 @@ xref: EHDAA:5526 xref: EMAPA:17082 xref: HBA:9512 xref: MA:0000205 -xref: MESH:D054024 +xref: MESH:D054024 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: VHOG:0000456 xref: Wikipedia:Myelencephalon is_a: UBERON:0004121 ! ectoderm-derived structure @@ -221600,7 +221941,7 @@ namespace: uberon def: "The elevation of thickened mesothelium and underlying mesenchyme found on the ventromedial border of the embryonic mesonephros in which the primordial germ cells become embedded, establishing it as the primordium of the testis or ovary." [MGI:anna, MP:0011411] subset: efo_slim subset: pheno_slim -synonym: "crista gonadalis" RELATED LATIN [Wikipedia:Gonadal_ridge] +synonym: "crista gonadalis" RELATED OMO:0003011 [Wikipedia:Gonadal_ridge] synonym: "genital cord" RELATED [MP:0011411] synonym: "genital ridge" EXACT [MP:0011411, Wikipedia:Gonadal_ridge] synonym: "gonadal ridge" EXACT [Wikipedia:Gonadal_ridge] @@ -221826,7 +222167,7 @@ relationship: part_of UBERON:0000080 ! mesonephros id: UBERON:0005321 name: mesonephric smooth muscle tissue namespace: uberon -def: "." [GO:0061214] +def: "Missing definition for term UBERON:0005321. Please replace it using linked reference." [GO:0061214] is_a: UBERON:0001135 ! smooth muscle tissue intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0000080 ! mesonephros @@ -222060,6 +222401,7 @@ xref: BAMS:CTXpl xref: DHBA:10515 xref: EMAPA:32711 xref: MBA:695 +xref: MESH:D002540 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} xref: neuronames:2702 xref: PBA:294021914 is_a: UBERON:0014950 ! layer of developing cerebral cortex @@ -222073,7 +222415,7 @@ name: spermatic cord namespace: uberon def: "The cord-like structure in males comprising the vas deferens and associated tissue that runs from the abdomen down to each testis[MP]." [MP:0010145, Wikipedia:Spermatic_cord] subset: pheno_slim -synonym: "funiculus spermaticus" RELATED LATIN [Wikipedia:Spermatic_cord] +synonym: "funiculus spermaticus" RELATED OMO:0003011 [Wikipedia:Spermatic_cord] synonym: "spermatic chord" RELATED [] xref: FMA:19937 xref: GAID:395 @@ -222256,13 +222598,13 @@ name: hippocampus stratum oriens namespace: uberon def: "Layer that is part of the CA fields of the hippocampus consisting of a narrow relatively cell free layer located deep to the pyramidal cell layer extending through areas CA1, CA2 and CA3. (adapted from Paxinos The rat central nervous system, 2nd ed, Academic Press, San Diego, 1995)." [BIRNLEX:4113] subset: pheno_slim -synonym: "gyrus cuneus" RELATED LATIN [NeuroNames:157] +synonym: "gyrus cuneus" RELATED OMO:0003011 [NeuroNames:157] synonym: "oriens layer of hippocampus" EXACT [BIRNLEX:4113] synonym: "oriens layer of the hippocampus" EXACT [BIRNLEX:4113] synonym: "polymorphic layer of hippocampus" EXACT [BIRNLEX:4113] synonym: "polymorphic layer of the hippocampus" EXACT [BIRNLEX:4113] synonym: "stratum oriens" EXACT [BIRNLEX:4113] -synonym: "stratum oriens hippocampi" EXACT LATIN [FMA:83893, FMA:TA] +synonym: "stratum oriens hippocampi" EXACT OMO:0003011 [FMA:83893, FMA:TA] xref: BAMS:Or xref: BIRNLEX:4113 xref: EMAPA:35412 @@ -222284,7 +222626,7 @@ def: "The layer located immediately above the pyramidal cell layer in CA2 and CA subset: pheno_slim synonym: "radiate layer of hippocampus" EXACT [FMA:83894] synonym: "stratum radiatum" EXACT [BIRNLEX:1298] -synonym: "stratum radiatum hippocampi" EXACT LATIN [FMA:83894, FMA:TA] +synonym: "stratum radiatum hippocampi" EXACT OMO:0003011 [FMA:83894, FMA:TA] synonym: "stratum radiatum of the hippocampus" RELATED [BAMS:Rad] xref: BAMS:Rad xref: BIRNLEX:1298 @@ -222393,7 +222735,7 @@ synonym: "dentate gyrus, granule cell layer" RELATED [BAMS:DG-sg] synonym: "DG granule cell layer" EXACT [BIRNLEX:4129] synonym: "granular layer of dentate gyrus" EXACT [FMA:83146] synonym: "granular layer of the dentate gyrus" RELATED [BAMS:GrDG] -synonym: "stratum granulare gyri dentati" EXACT LATIN [FMA:83146, FMA:TA] +synonym: "stratum granulare gyri dentati" EXACT OMO:0003011 [FMA:83146, FMA:TA] xref: BAMS:DG-sg xref: BAMS:GrDG xref: BAMS:sg @@ -222535,8 +222877,8 @@ synonym: "olfactory area of nasal mucosa" EXACT [FMA:77199] synonym: "olfactory mucosa" EXACT [] synonym: "olfactory part of nasal mucosa" EXACT [FMA:77199] synonym: "olfactory zone of nasal mucosa" EXACT [FMA:77199] -synonym: "pars olfactoria tunicae mucosae nasi" EXACT LATIN [FMA:77199, FMA:TA] -synonym: "pars olfactoria tunicae mucosae nasi" RELATED LATIN [Wikipedia:Olfactory_mucosa] +synonym: "pars olfactoria tunicae mucosae nasi" EXACT OMO:0003011 [FMA:77199, FMA:TA] +synonym: "pars olfactoria tunicae mucosae nasi" RELATED OMO:0003011 [Wikipedia:Olfactory_mucosa] xref: CALOHA:TS-2197 xref: EMAPA:37918 {source="MA:th"} xref: FMA:77199 @@ -222560,7 +222902,7 @@ name: photoreceptor array namespace: uberon def: "An array of photoreceptors and any supporting cells found in an eye." [https://orcid.org/0000-0002-6601-2165] synonym: "light-sensitive tissue" EXACT [] -xref: FBbt:00004200 +xref: FBbt:00004200 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0004923 ! organ component layer intersection_of: UBERON:0004923 ! organ component layer intersection_of: composed_primarily_of CL:0000210 ! photoreceptor cell @@ -222587,7 +222929,7 @@ name: cortical layer I namespace: uberon def: "The most superficial layer of the neocortex characterized by a paucity of cell bodies." [NLXANAT:090807] synonym: "cerebral cortex, layer 1" EXACT [ABA:CTX1] -synonym: "lamina molecularis isocorticis [lamina I]" EXACT LATIN [FMA:83900, FMA:TA] +synonym: "lamina molecularis isocorticis [lamina I]" EXACT OMO:0003011 [FMA:83900, FMA:TA] synonym: "layer 1 of neocortex" EXACT [NLXANAT:090807] synonym: "layer I of neocortex" EXACT [NLXANAT:090807] synonym: "molecular layer" RELATED [] @@ -222628,7 +222970,7 @@ synonym: "external granular layer of neocortex" EXACT [FMA:77804] synonym: "external granule cell layer" RELATED [] synonym: "external granule cell layer of neocortex" EXACT [NLXANAT:090808] synonym: "granule cell layer of cerebral cortex" RELATED [] -synonym: "lamina granularis externa isocorticis [lamina ii]" EXACT LATIN [FMA:77804, FMA:TA] +synonym: "lamina granularis externa isocorticis [lamina ii]" EXACT OMO:0003011 [FMA:77804, FMA:TA] synonym: "layer II of neocortex" EXACT [NLXANAT:090808] synonym: "neocortex layer 2" EXACT [NLXANAT:090808] synonym: "neocortex layer II" EXACT [NLXANAT:090808] @@ -222657,8 +222999,8 @@ synonym: "external pyramidal layer of cerebral cortex" RELATED [ncithesaurus:Ext synonym: "external pyramidal layer of isocortex [layer iii]" EXACT [FMA:77810] synonym: "external pyramidal layer of neocortex" EXACT [FMA:77810] synonym: "isocortex, deep supragranular pyramidal layer" RELATED [NeuroNames:2448] -synonym: "lamina pyramidalis externa" RELATED LATIN [NeuroNames:2448] -synonym: "lamina pyramidalis externa isocorticis [lamina iii]" EXACT LATIN [FMA:77810, FMA:TA] +synonym: "lamina pyramidalis externa" RELATED OMO:0003011 [NeuroNames:2448] +synonym: "lamina pyramidalis externa isocorticis [lamina iii]" EXACT OMO:0003011 [FMA:77810, FMA:TA] synonym: "layer 3 of neocortex" EXACT [NLXANAT:090809] synonym: "layer III of neocortex" EXACT [NLXANAT:090809] synonym: "layer of medium-sized and large pyramidal cells" RELATED [NeuroNames:2448] @@ -222690,7 +223032,7 @@ synonym: "internal granular layer" RELATED [] synonym: "internal granular layer of isocortex [layer iv]" EXACT [FMA:77811] synonym: "internal granular layer of neocortex" EXACT [FMA:77811] synonym: "internal granule cell layer of neocortex" EXACT [NLXANAT:090810] -synonym: "lamina granularis interna isocorticis [lamina iv]" EXACT LATIN [FMA:77811, FMA:TA] +synonym: "lamina granularis interna isocorticis [lamina iv]" EXACT OMO:0003011 [FMA:77811, FMA:TA] synonym: "layer 4 of neocortex" EXACT [NLXANAT:090810] synonym: "layer IV of neocortex" EXACT [NLXANAT:090810] synonym: "neocortex internal granule cell layer" EXACT [NLXANAT:090810] @@ -222729,9 +223071,9 @@ synonym: "internal pyramidal layer" RELATED [NeuroNames:2450] synonym: "internal pyramidal layer of isocortex [layer v]" EXACT [FMA:77812] synonym: "internal pyramidal layer of neocortex" EXACT [FMA:77812] synonym: "isocortex, infragranular pyramidal layer" RELATED [NeuroNames:2450] -synonym: "lamina ganglionaris" RELATED LATIN [NeuroNames:2450] -synonym: "lamina pyramidalis interna" RELATED LATIN [NeuroNames:2450] -synonym: "lamina pyramidalis interna isocorticis [lamina v]" EXACT LATIN [FMA:77812, FMA:TA] +synonym: "lamina ganglionaris" RELATED OMO:0003011 [NeuroNames:2450] +synonym: "lamina pyramidalis interna" RELATED OMO:0003011 [NeuroNames:2450] +synonym: "lamina pyramidalis interna isocorticis [lamina v]" EXACT OMO:0003011 [FMA:77812, FMA:TA] synonym: "layer 5 of neocortex" EXACT [NLXANAT:090811] synonym: "layer V of neocortex" EXACT [NLXANAT:090811] synonym: "neocortex internal pyramidal cell layer" EXACT [NLXANAT:090811] @@ -222761,8 +223103,8 @@ def: "Innermost layer of neocortex lying deep to the internal pyramidal cell lay synonym: "cerebral cortex, layer 6" EXACT [ABA:CTX6] synonym: "fusiform layer" RELATED [NeuroNames:2451] synonym: "isocortex, polymorph layer" RELATED [NeuroNames:2451] -synonym: "lamina multiformis" RELATED LATIN [NeuroNames:2451] -synonym: "lamina multiformis isocorticis [lamina vi]" EXACT LATIN [FMA:77805, FMA:TA] +synonym: "lamina multiformis" RELATED OMO:0003011 [NeuroNames:2451] +synonym: "lamina multiformis isocorticis [lamina vi]" EXACT OMO:0003011 [FMA:77805, FMA:TA] synonym: "layer VI of neocortex" EXACT [NLXANAT:090812] synonym: "multiform layer" RELATED [NeuroNames:2451] synonym: "multiform layer of isocortex [layer vi]" EXACT [FMA:77805] @@ -222827,8 +223169,8 @@ id: UBERON:0005397 name: brain arachnoid mater namespace: uberon def: "An arachnoid mater that surrounds a brain." [OBOL:automatic] -synonym: "arachnoidea mater cranialis" EXACT LATIN [FMA:83981, FMA:TA] -synonym: "arachnoidea mater encephali" EXACT LATIN [FMA:83981, FMA:TA] +synonym: "arachnoidea mater cranialis" EXACT OMO:0003011 [FMA:83981, FMA:TA] +synonym: "arachnoidea mater encephali" EXACT OMO:0003011 [FMA:83981, FMA:TA] synonym: "brain arachnoid matter" EXACT [MA:0000814] synonym: "cranial arachnoid mater" EXACT [FMA:83981] xref: EMAPA:32661 @@ -222927,7 +223269,7 @@ xref: EMAPA:36576 xref: FMA:77614 xref: MA:0002972 xref: MBA:493 -xref: MESH:D066328 +xref: MESH:D066328 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: neuronames:2341 xref: NLX:57107 xref: PBA:10091 @@ -222943,7 +223285,7 @@ name: perirenal fat namespace: uberon def: "The adipose capsule of kidney (or perinephric fat or perirenal fat) is a structure between the renal fascia and renal capsule, and may be regarded as a part of the latter. A different structure, the pararenal fat, is the adipose tissue superficial to the renal fascia." [Wikipedia:Adipose_capsule_of_kidney] synonym: "adipose capsule of kidney" RELATED [MA:0002975] -synonym: "capsula adiposa renis" RELATED LATIN [Wikipedia:Adipose_capsule_of_kidney] +synonym: "capsula adiposa renis" RELATED OMO:0003011 [Wikipedia:Adipose_capsule_of_kidney] synonym: "fatty capsule of kidney" RELATED [MA:0002975] synonym: "perinephric fat" RELATED [MA:0002975] synonym: "periphrenic fascia" RELATED [MA:0002975] @@ -222971,11 +223313,11 @@ subset: pheno_slim synonym: "circumventricular organ" EXACT [NLXANAT:20090312] synonym: "circumventricular organ of neuraxis" EXACT [FMA:84081] synonym: "CVO" EXACT OMO:0003000 [NLXANAT:20090312] -xref: BTO:0006267 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: BTO:0006267 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: EMAPA:35243 xref: FMA:84081 xref: MA:0002942 -xref: MESH:D066280 +xref: MESH:D066280 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: neuronames:1242 xref: NLXANAT:20090312 xref: Wikipedia:Circumventricular_organs @@ -223240,7 +223582,7 @@ synonym: "developmental tissue" RELATED [MIAA:0000019] xref: AEO:0000125 xref: CALOHA:TS-2122 xref: EHDAA2:0003125 -xref: FBbt:00007006 +xref: FBbt:00007006 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:292313 xref: MIAA:0000019 is_a: UBERON:0000465 ! material anatomical entity @@ -223369,7 +223711,7 @@ name: aortic sac namespace: uberon def: "The dilated structure that is lined by endothelial cells and located at the arterial pole of the heart just above (distal to) the truncus arteriosus in mammalian embryos; it is the primordial vascular channel from which the aortic arches (and eventually the dorsal aortae) arise; the aortic sac is homologous to the ventral aorta of gill-bearing vertebrates." [MP:0012510] subset: pheno_slim -synonym: "saccus aorticus" EXACT LATIN [] +synonym: "saccus aorticus" EXACT OMO:0003011 [] xref: EHDAA2:0004145 xref: EHDAA:9826 xref: EMAPA:36461 @@ -223403,7 +223745,7 @@ name: common hepatic artery namespace: uberon def: "In anatomy, the common hepatic artery is a short blood vessel that supplies oxygenated blood to the liver, pylorus (a part of the stomach), duodenum (a part of the small intestine) and pancreas. It arises from the celiac artery and has the following branches:." [Wikipedia:Common_hepatic_artery] subset: human_reference_atlas -synonym: "arteria hepatica communis" RELATED LATIN [Wikipedia:Common_hepatic_artery] +synonym: "arteria hepatica communis" RELATED OMO:0003011 [Wikipedia:Common_hepatic_artery] synonym: "common hepatic" RELATED [Wikipedia:Common_hepatic_artery] xref: EHDAA2:0000308 xref: EHDAA:8570 @@ -223428,7 +223770,7 @@ def: "A segment of autopod that is part of a pes." [OBOL:automatic] subset: pheno_slim synonym: "foot region" BROAD [FMA:24993] synonym: "foot subdivision" EXACT [FMA:24993] -synonym: "regio pedis" EXACT LATIN [FMA:24993, FMA:TA] +synonym: "regio pedis" EXACT OMO:0003011 [FMA:24993, FMA:TA] synonym: "segment of foot" EXACT [FMA:24993] synonym: "subdivision of foot" EXACT [FMA:24993] xref: FMA:24993 @@ -223445,7 +223787,7 @@ name: foramen rotundum namespace: uberon def: "The foramen rotundum is a circular hole in the sphenoid bone that connects the middle cranial fossa and the pterygopalatine fossa." [Wikipedia:Foramen_rotundum] synonym: "foramen rotundum of the skull" RELATED [Wikipedia:Foramen_rotundum] -synonym: "foramen rotundum ossis sphenoidalis" RELATED LATIN [Wikipedia:Foramen_rotundum] +synonym: "foramen rotundum ossis sphenoidalis" RELATED OMO:0003011 [Wikipedia:Foramen_rotundum] synonym: "round foramen" RELATED [VHOG:0001543] xref: AAO:0000194 xref: EHDAA2:0000552 @@ -223474,7 +223816,7 @@ def: "A segment of autopod that is part of a manus." [OBOL:automatic] subset: pheno_slim synonym: "hand region" BROAD [FMA:24945] synonym: "hand subdivision" EXACT [FMA:24945] -synonym: "regio manus" EXACT LATIN [] +synonym: "regio manus" EXACT OMO:0003011 [] synonym: "segment of hand" EXACT [FMA:24945] synonym: "subdivision of hand" EXACT [FMA:24945] xref: FMA:24945 @@ -223497,7 +223839,7 @@ xref: EHDAA2:0000893 xref: EHDAA:10631 xref: EMAPA:18713 xref: FMA:56432 -xref: MESH:D000080869 +xref: MESH:D000080869 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: NCIT:C12496 xref: SCTID:361735006 xref: UMLS:C0222712 {source="ncithesaurus:Jugular_Foramen"} @@ -223591,7 +223933,7 @@ synonym: "levator scapula" RELATED [Wikipedia:Levator_scapulae_muscle] synonym: "levator scapulae" EXACT [FMA:32519] synonym: "levator scapulae muscle" RELATED [Wikipedia:Levator_scapulae_muscle] synonym: "levator scapulæ" RELATED [Wikipedia:Levator_scapulae_muscle] -synonym: "musculus levator scapulae" RELATED LATIN [Wikipedia:Levator_scapulae_muscle] +synonym: "musculus levator scapulae" RELATED OMO:0003011 [Wikipedia:Levator_scapulae_muscle] xref: AAO:0010689 xref: EHDAA2:0000992 xref: EHDAA:8309 @@ -223781,7 +224123,7 @@ synonym: "cranial dural venous sinus" EXACT [FMA:50762] synonym: "dural sinus" EXACT [FMA:50762] synonym: "dural vein" EXACT [MA:0002113] synonym: "dural venous sinus" EXACT [FMA:50762] -synonym: "s. durae matris" RELATED LATIN [Wikipedia:Dural_venous_sinuses] +synonym: "s. durae matris" RELATED OMO:0003011 [Wikipedia:Dural_venous_sinuses] synonym: "venous dural" EXACT [EHDAA:6491] synonym: "venous dural sinus" EXACT [EHDAA2:0002169] xref: EHDAA2:0002169 @@ -223813,7 +224155,7 @@ synonym: "embryonic vitelline vein" EXACT [VHOG:0000401] synonym: "omphalomesenteric vein" RELATED [EMAPA:16244] synonym: "vascular vitelline network" EXACT [XAO:0004147] synonym: "vein of omphalomesenteric system" RELATED [] -synonym: "vena vitellina" EXACT LATIN [Wikipedia:Vitelline_veins] +synonym: "vena vitellina" EXACT OMO:0003011 [Wikipedia:Vitelline_veins] synonym: "vitelline veins" RELATED OMO:0003004 [XAO:0004147] xref: EMAPA:36021 xref: FMA:70305 @@ -223900,7 +224242,7 @@ def: "Multi-tissue structure that arises from the heart rudiment and will become subset: vertebrate_core synonym: "early primitive heart tube" NARROW [EMAPA:16208] synonym: "primitive heart tube" EXACT [EMAPA:16215] -xref: BTO:0006179 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: BTO:0006179 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: EHDAA2:0001512 xref: EHDAA:424 xref: EHDAA:436 @@ -224376,7 +224718,7 @@ id: UBERON:0005629 name: vascular plexus namespace: uberon def: "A vascular network formed by frequent anastomoses between the blood vessels (arteries or veins) of a part." [http://www.medilexicon.com/medicaldictionary.php?t=70052] -synonym: "plexus vasculosus" EXACT LATIN [] +synonym: "plexus vasculosus" EXACT OMO:0003011 [] xref: AEO:0000219 xref: EHDAA2:0004112 xref: EMAPA:35904 @@ -224394,7 +224736,7 @@ namespace: uberon def: "Intrinsic membrane that arises from embryonic germ layers and grow to surround the developing embryo." [ISBN:0073040584] xref: EHDAA2:0004714 xref: FMA:305915 -xref: MESH:D005321 +xref: MESH:D005321 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: SCTID:362840007 is_a: UBERON:0000158 ! membranous layer relationship: part_of UBERON:0016887 ! entire extraembryonic component @@ -224885,7 +225227,6 @@ relationship: capable_of GO:0007606 ! sensory perception of chemical stimulus id: UBERON:0005728 name: extraembryonic mesoderm namespace: uberon -def: "." [http://www.ana.ed.ac.uk/database/humat/notes/extraemb/mesoder.htm] synonym: "extra-embryonic mesoderm" EXACT [] synonym: "extraembryonic mesenchyme" EXACT [] xref: EHDAA2:0000474 @@ -224969,8 +225310,8 @@ synonym: "adventitia externa" EXACT [Wikipedia:Tunica_externa_(vessels)] synonym: "external coat" RELATED [Wikipedia:Tunica_externa_(vessels)] synonym: "tunica adventitia" EXACT [Wikipedia:Tunica_externa_(vessels)] synonym: "tunica adventitia of vessel" EXACT [Wikipedia:Tunica_externa_(vessels)] -synonym: "tunica adventitia vasorum" RELATED LATIN [Wikipedia:Tunica_externa_(vessels)] -synonym: "tunica externa vasorum" RELATED LATIN [Wikipedia:Tunica_externa_(vessels)] +synonym: "tunica adventitia vasorum" RELATED OMO:0003011 [Wikipedia:Tunica_externa_(vessels)] +synonym: "tunica externa vasorum" RELATED OMO:0003011 [Wikipedia:Tunica_externa_(vessels)] xref: BTO:0002010 xref: EMAPA:36299 xref: NCIT:C33818 @@ -225015,7 +225356,7 @@ synonym: "tunica advetitia" NARROW [Wikipedia:Adventitia] synonym: "tunica externa" NARROW [FMA:45635] xref: BTO:0002010 xref: FMA:45635 -xref: MESH:D063194 +xref: MESH:D063194 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: SCTID:30180000 xref: Wikipedia:Adventitia is_a: UBERON:0004923 ! organ component layer @@ -225050,8 +225391,8 @@ def: "An opening in the skull through which cranial nerve II passes.[MP]." [http comment: In teleost fishes the opening is wider that in mammals. Due to the longer and deeper shape in mammals, this is usually called the optic canal; sometimes the term optic foramen may be used for the opening of the canal, but here we use this term to denote the entire space together with surrounding bone surface. subset: pheno_slim subset: vertebrate_core -synonym: "canalis opticus" RELATED LATIN [Wikipedia:Optic_canal] -synonym: "foramen opticum ossis sphenoidalis" RELATED LATIN [Wikipedia:Optic_canal] +synonym: "canalis opticus" RELATED OMO:0003011 [Wikipedia:Optic_canal] +synonym: "foramen opticum ossis sphenoidalis" RELATED OMO:0003011 [Wikipedia:Optic_canal] synonym: "optic canal" EXACT [Wikipedia:Optic_canal] synonym: "optic foramen" EXACT [Wikipedia:Optic_canal] synonym: "optic nerve (II) foramen" EXACT [ZFA:0005428, ZFIN:ZDB-PUB-961014-192] @@ -225193,7 +225534,7 @@ namespace: uberon def: "The ridge of mesoderm covered with endoderm that in the early developing embryo partitions the endodermal cloaca into the primary urogenital sinus (ventrally) and the anorectal canal of the hindgut (dorsally); the urorectal septum eventually fuses with the cloacal membrane, dividing it into a dorsal anal membrane and a larger ventral urogenital membrane - this area of fusion is represented in the adult by the perineal body[MP]." [MP:anna, Wikipedia:Urorectal_septum] subset: pheno_slim synonym: "cloacal septum" RELATED [VHOG:0000018] -synonym: "septum urorectale" EXACT LATIN [Wikipedia:Urorectal_septum] +synonym: "septum urorectale" EXACT OMO:0003011 [Wikipedia:Urorectal_septum] synonym: "urorectal fold" EXACT [MP:anna] synonym: "urorectal membrane" EXACT [MP:anna] xref: EHDAA2:0002152 @@ -225235,7 +225576,7 @@ namespace: uberon def: "An acellular membrane that is part of the epithelium, lies adjacent to the epithelial cells, and is the fusion of the the basal lamina and the reticular lamina." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Basement_membrane] synonym: "basement membrane" RELATED [FMA:63872] synonym: "basement membrane of connective tissue" EXACT [FMA:63872] -synonym: "membrana basalis" EXACT LATIN [Wikipedia:Basement_membrane] +synonym: "membrana basalis" EXACT OMO:0003011 [Wikipedia:Basement_membrane] xref: AAO:0010596 xref: FMA:63872 xref: GAID:915 @@ -225267,7 +225608,7 @@ xref: EMAPA:28251 xref: EMAPA:30965 xref: FMA:74274 xref: MA:0001659 -xref: MESH:D050533 +xref: MESH:D050533 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: NCIT:C32683 xref: SCTID:243897006 xref: TAO:0005285 @@ -225393,8 +225734,8 @@ name: dorsal aorta namespace: uberon def: "The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once." [GO:0035907, https://sourceforge.net/p/geneontology/ontology-requests/8525/] subset: vertebrate_core -synonym: "aorta dorsalis" EXACT LATIN [XAO:0000051] -synonym: "aortae dorsales" RELATED LATIN [Wikipedia:Dorsal_aorta] +synonym: "aorta dorsalis" EXACT OMO:0003011 [XAO:0000051] +synonym: "aortae dorsales" RELATED OMO:0003011 [Wikipedia:Dorsal_aorta] synonym: "DA" EXACT [ZFA:0000014] synonym: "dorsal aorta root" RELATED [VHOG:0000264] synonym: "dorsal aortae" RELATED OMO:0003004 [Wikipedia:Dorsal_aorta] @@ -225539,9 +225880,9 @@ def: "A spinal cord segment that adjacent_to a caudal region." [OBOL:automatic] comment: for spinal cord segments, we treat coccygeal/caudal as synonyms - we only differentiate where bone is concerned synonym: "coccygeal segment of spinal cord" EXACT [FMA:256635] synonym: "coccygeal segments of spinal cord [1-3]" EXACT [FMA:256635] -synonym: "pars coccygea medullae spinalis" EXACT LATIN [FMA:256635, FMA:TA] -synonym: "segmenta coccygea" RELATED LATIN [NeuroNames:1656] -synonym: "segmenta coccygea medullae spinalis [1-3]" EXACT LATIN [FMA:256635, FMA:TA] +synonym: "pars coccygea medullae spinalis" EXACT OMO:0003011 [FMA:256635, FMA:TA] +synonym: "segmenta coccygea" RELATED OMO:0003011 [NeuroNames:1656] +synonym: "segmenta coccygea medullae spinalis [1-3]" EXACT OMO:0003011 [FMA:256635, FMA:TA] xref: FMA:256635 xref: MA:0003084 xref: neuronames:1656 @@ -225624,7 +225965,7 @@ def: "The paired ventral prominences formed by bifurcation of the first pharynge subset: pheno_slim synonym: "mandibular process" RELATED [Wikipedia:Mandibular_prominence] synonym: "mandibular swelling" RELATED [https://orcid.org/0000-0002-6601-2165] -synonym: "prominentia mandibularis" RELATED LATIN [Wikipedia:Mandibular_prominence] +synonym: "prominentia mandibularis" RELATED OMO:0003011 [Wikipedia:Mandibular_prominence] xref: EHDAA2:0001061 xref: EHDAA:5871 xref: EMAPA:17355 @@ -225646,7 +225987,7 @@ subset: pheno_slim synonym: "embryonic maxillary process" EXACT [] synonym: "maxillary process" EXACT [EHDAA2:0001070] synonym: "maxillary process of embryo" EXACT [] -synonym: "prominentia maxilaris" RELATED LATIN [Wikipedia:Maxillary_prominence] +synonym: "prominentia maxilaris" RELATED OMO:0003011 [Wikipedia:Maxillary_prominence] xref: EHDAA2:0001070 xref: EHDAA:5877 xref: EMAPA:17359 @@ -225795,8 +226136,8 @@ def: "The embryonic anlage of the external genitalia, which emerges as paired sw subset: pheno_slim synonym: "genital tubercle" RELATED [EMAPA:17382] synonym: "phallic tubercle" RELATED [] -synonym: "tuberculum genitale" RELATED LATIN [Wikipedia:Genital_tubercle] -synonym: "tuberculum phallicum" RELATED LATIN [Wikipedia:Genital_tubercle] +synonym: "tuberculum genitale" RELATED OMO:0003011 [Wikipedia:Genital_tubercle] +synonym: "tuberculum phallicum" RELATED OMO:0003011 [Wikipedia:Genital_tubercle] synonym: "undifferentiated genital tubercle" EXACT [VHOG:0000583] xref: EHDAA2:0000705 xref: EHDAA:5925 @@ -225833,7 +226174,7 @@ synonym: "pharyngeal ectodermal cleft" RELATED [] synonym: "pharyngeal groove" BROAD [Wikipedia:Pharyngeal_groove] synonym: "pharyngeal groove ectoderm" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "pharyngeal slit" RELATED INCONSISTENT [] -synonym: "sulcus pharyngei" RELATED LATIN [Wikipedia:Pharyngeal_groove] +synonym: "sulcus pharyngei" RELATED OMO:0003011 [Wikipedia:Pharyngeal_groove] xref: AAO:0010623 xref: EMAPA:32750 xref: FMA:295672 @@ -225868,8 +226209,8 @@ synonym: "alar lamina" RELATED [Wikipedia:Alar_lamina] synonym: "alar plate" EXACT [NeuroNames:1370] synonym: "alar plate of neural tube" EXACT [] synonym: "dorsal part of neural tube" RELATED [] -synonym: "lamina alaris" RELATED LATIN [Wikipedia:Alar_plate] -synonym: "lamina dorsolateralis" RELATED LATIN [Wikipedia:Alar_plate] +synonym: "lamina alaris" RELATED OMO:0003011 [Wikipedia:Alar_plate] +synonym: "lamina dorsolateralis" RELATED OMO:0003011 [Wikipedia:Alar_plate] synonym: "sensory part of neural tube" RELATED [] xref: neuronames:1370 xref: Wikipedia:Alar_plate @@ -225995,6 +226336,7 @@ synonym: "occipital region of head" EXACT [FMA:49187] xref: AAO:0010199 xref: BTO:0004675 xref: FMA:49187 +xref: MESH:D009778 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} xref: neuronames:2431 xref: SCTID:362618001 xref: TAO:0001414 @@ -226012,8 +226354,8 @@ name: duct of seminal vesicle namespace: uberon def: "Each seminal vesicle consists of a single tube, coiled upon itself, and giving off several irregular cecal diverticula; the separate coils, as well as the diverticula, are connected together by fibrous tissue. When uncoiled, the tube is about the diameter of a quill, and varies in length from 10 to 15 cm.; it ends posteriorly in a cul-de-sac; its anterior extremity becomes constricted into a narrow straight duct called the excretory duct of seminal gland (or duct of the seminal vesicle), which joins with the corresponding ductus deferens to form the ejaculatory duct[WP]." [Wikipedia:Excretory_duct_of_seminal_gland] synonym: "ductus excretorius (vesicula seminalis)" EXACT [FMA:19473] -synonym: "ductus excretorius glandulae vesiculosae" EXACT LATIN [FMA:19473, FMA:TA] -synonym: "ductus excretorius glandulae vesiculosae" RELATED LATIN [Wikipedia:Excretory_duct_of_seminal_gland] +synonym: "ductus excretorius glandulae vesiculosae" EXACT OMO:0003011 [FMA:19473, FMA:TA] +synonym: "ductus excretorius glandulae vesiculosae" RELATED OMO:0003011 [Wikipedia:Excretory_duct_of_seminal_gland] synonym: "excretory duct of seminal gland" EXACT [FMA:19473] synonym: "seminal vesicle duct" EXACT [FMA:19473] xref: EMAPA:29282 @@ -226159,12 +226501,12 @@ property_value: seeAlso "https://github.com/obophenotype/mouse-anatomy-ontology/ id: UBERON:0005933 name: hair root sheath namespace: uberon -def: "." [https://github.com/obophenotype/mouse-anatomy-ontology/issues/56] xref: EMAPA:18772 xref: FMA:294628 xref: MA:0000162 is_a: UBERON:0000479 ! tissue relationship: part_of UBERON:0005932 ! bulb of hair follicle +property_value: seeAlso "https://github.com/obophenotype/mouse-anatomy-ontology/issues/56" xsd:anyURI [Term] id: UBERON:0005941 @@ -226214,7 +226556,7 @@ def: "Subdivision of skeleton which consists of cranial skeleton, set of all ver subset: human_reference_atlas subset: pheno_slim subset: uberon_slim -synonym: "skeleton axiale" RELATED LATIN [Wikipedia:Axial_skeleton] +synonym: "skeleton axiale" RELATED OMO:0003011 [Wikipedia:Axial_skeleton] xref: AAO:0000963 xref: EMAPA:17214 xref: EMAPA:18043 @@ -226305,7 +226647,7 @@ synonym: "left ventricular outflow tract" EXACT [HP:0011103] synonym: "LVOT" EXACT OMO:0003000 [MP:0010429] synonym: "outflow tract of left ventricle" EXACT [FMA:9473] synonym: "Sibson vestibule" EXACT [MP:0010429] -synonym: "vestibulum aortae" EXACT LATIN [FMA:9473, FMA:TA] +synonym: "vestibulum aortae" EXACT OMO:0003011 [FMA:9473, FMA:TA] xref: EMAPA:37925 {source="MA:th"} xref: FMA:9473 xref: SCTID:264070001 @@ -226360,7 +226702,7 @@ synonym: "ligamentum pectinatum iridis" RELATED [Wikipedia:Trabecular_meshwork] synonym: "pectinate ligament" RELATED [BTO:0001605] synonym: "pectinate ligament of iris" RELATED [BTO:0001605] synonym: "reticulum trabeculare" EXACT [BTO:0001605] -synonym: "reticulum trabeculare sclerae" RELATED LATIN [Wikipedia:Trabecular_meshwork] +synonym: "reticulum trabeculare sclerae" RELATED OMO:0003011 [Wikipedia:Trabecular_meshwork] synonym: "scleral trabeculae" RELATED [Wikipedia:Trabecular_meshwork] synonym: "scleral trabecular" RELATED [Wikipedia:Trabecular_meshwork] synonym: "scleral trabecule" RELATED [Wikipedia:Trabecular_meshwork] @@ -226410,7 +226752,7 @@ name: crista terminalis namespace: uberon def: "The vertical crest of the interior wall of the right atrium that lies to the right of the sinus of the vena cava and separates this from the remainder of the right atrium." [MP:0010495] subset: pheno_slim -synonym: "crista terminalis atrii dextri" EXACT LATIN [FMA:9236, FMA:TA] +synonym: "crista terminalis atrii dextri" EXACT OMO:0003011 [FMA:9236, FMA:TA] synonym: "crista terminalis cordis" EXACT [FMA:9236] synonym: "crista terminalis of right atrium" EXACT [FMA:9236] xref: EMAPA:37837 {source="MA:th"} @@ -226456,7 +226798,7 @@ namespace: uberon def: "The left branch of the atrioventricular bundle that separates at the bundle of His, descends the septal wall of the left ventricle and connects to the terminal Purkinje fiber[MP]." [MP:0010566] subset: pheno_slim synonym: "crus sinistrum (fasciculi atrioventricularis)" EXACT [FMA:9487] -synonym: "crus sinistrum fasciculi atrioventricularis" EXACT LATIN [FMA:9487, FMA:TA] +synonym: "crus sinistrum fasciculi atrioventricularis" EXACT OMO:0003011 [FMA:9487, FMA:TA] synonym: "LBB" EXACT OMO:0003000 [] synonym: "left branch of atrioventricular bundle" EXACT [] synonym: "left bundle branch" EXACT [MP:0010566] @@ -226481,7 +226823,7 @@ namespace: uberon def: "The right branch of the atrioventricular bundle that separates just below the bundle of His, descends the septal wall of the right ventricle and connects to the terminal Purkinje fibers[MP]." [MP:0010567] subset: pheno_slim synonym: "crus dextrum (fasciculi atrioventricularis)" EXACT [FMA:9486] -synonym: "crus dextrum fasciculi atrioventricularis" EXACT LATIN [FMA:9486, FMA:TA] +synonym: "crus dextrum fasciculi atrioventricularis" EXACT OMO:0003011 [FMA:9486, FMA:TA] synonym: "RBB" EXACT OMO:0003000 [] synonym: "right branch of atrioventricular bundle" EXACT [] synonym: "right bundle" EXACT [FMA:9486, MP:0010567] @@ -226562,7 +226904,7 @@ name: integumentary adnexa namespace: uberon def: "Anatomical structure embedded in or located in the integument that is part of the integumental system. Examples: hair, follicles, skin glands, claws, nails, feathers." [http://code.google.com/p/caro2/issues/detail?id=5, http://orcid.org/0000-0002-6601-2165] subset: pheno_slim -synonym: "adnexae cutis" RELATED LATIN [Wikipedia:Skin_appendage] +synonym: "adnexae cutis" RELATED OMO:0003011 [Wikipedia:Skin_appendage] synonym: "body hair or bristle" NARROW [GO:GO] synonym: "skin adnexa" RELATED [Wikipedia:Skin_appendage] synonym: "skin adnexal structure" RELATED [] @@ -226597,7 +226939,7 @@ id: UBERON:0006008 name: fibrous ring of heart namespace: uberon def: "A ring of ribrous tissue that surrounds the atrioventricular and arterial orifices." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Fibrous_rings_of_heart] -synonym: "annulus fibrosus cordis" RELATED LATIN [Wikipedia:Fibrous_rings_of_heart] +synonym: "annulus fibrosus cordis" RELATED OMO:0003011 [Wikipedia:Fibrous_rings_of_heart] synonym: "anulus fibrosus cordis" RELATED [Wikipedia:Fibrous_rings_of_heart] synonym: "anulus fibrosus of heart" EXACT [FMA:9497] synonym: "aortic annulus" RELATED [Wikipedia:Fibrous_rings_of_heart] @@ -226822,7 +227164,7 @@ subset: pheno_slim synonym: "base of urinary bladder" EXACT [FMA:15908] synonym: "bladder dome" RELATED [EMAPA:35173] synonym: "fundus of bladder" BROAD [FMA:15908] -synonym: "fundus vesicae" EXACT LATIN [FMA:15908, FMA:TA] +synonym: "fundus vesicae" EXACT OMO:0003011 [FMA:15908, FMA:TA] synonym: "urinary bladder base" EXACT [MP:0011785] synonym: "urinary bladder fundus" EXACT [FMA:15908] synonym: "urinary bladder fundus region" EXACT [MA:0001694] @@ -226855,12 +227197,13 @@ synonym: "basal ganglia" RELATED INCONSISTENT [BIRNLEX:1629] synonym: "basal ganglia (anatomic)" RELATED [NeuroNames:224] synonym: "basal nuclei" EXACT [BIRNLEX:1629] synonym: "basal nuclei of the forebrain" EXACT [BIRNLEX:1629] -synonym: "corpus striatum (Savel'ev)" RELATED LATIN [NeuroNames:224] -synonym: "ganglia basales" RELATED LATIN [NeuroNames:224] +synonym: "corpus striatum (Savel'ev)" RELATED OMO:0003011 [NeuroNames:224] +synonym: "ganglia basales" RELATED OMO:0003011 [NeuroNames:224] xref: BAMS:BG xref: BAMS:BNC xref: BIRNLEX:1629 xref: EV:0100182 +xref: MESH:D001479 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} xref: neuronames:224 {source="BIRNLEX:1629"} xref: UMLS:C0004781 {source="BIRNLEX:1629"} is_a: UBERON:0007245 ! nuclear complex of neuraxis @@ -226918,8 +227261,8 @@ def: "A threadlike extension of a nerve cell and consists of an axon and myelin subset: human_reference_atlas synonym: "nerve fibers" RELATED OMO:0003004 [BAMS:nfi] synonym: "nerve fibre" EXACT [FMA:5914] -synonym: "neurofibra" EXACT LATIN [FMA:5914, FMA:TA] -synonym: "neurofibra" RELATED LATIN [Wikipedia:Nerve_fiber] +synonym: "neurofibra" EXACT OMO:0003011 [FMA:5914, FMA:TA] +synonym: "neurofibra" RELATED OMO:0003011 [Wikipedia:Nerve_fiber] synonym: "neurofibrum" EXACT [FMA:5914] xref: BAMS:nfi xref: FMA:5914 @@ -227017,7 +227360,7 @@ relationship: part_of UBERON:0005326 {is_inferred="true", source="https://github id: UBERON:0006183 name: mesonephric glomerular capillary namespace: uberon -def: "." [GO:0061249] +def: "Missing definition for term UBERON:0006183. Please replace it using linked reference." [GO:0061249] is_a: UBERON:0004212 ! glomerular capillary intersection_of: UBERON:0004212 ! glomerular capillary intersection_of: part_of UBERON:0000080 ! mesonephros @@ -227082,7 +227425,7 @@ subset: pheno_slim synonym: "aortic septum" RELATED [Wikipedia:Aorticopulmonary_septum] synonym: "aortico-pulmonary septum" EXACT [Wikipedia:Aorticopulmonary_septum] synonym: "aorticopulmonary septum" EXACT [Wikipedia:Aorticopulmonary_septum] -synonym: "septum aorticopulmonale" EXACT LATIN [Wikipedia:Aorticopulmonary_septum] +synonym: "septum aorticopulmonale" EXACT OMO:0003011 [Wikipedia:Aorticopulmonary_septum] synonym: "spiral septum" RELATED [Wikipedia:Aorticopulmonary_septum] xref: CALOHA:TS-2409 xref: EHDAA2:0000136 @@ -227235,7 +227578,7 @@ def: "The membrane that covers the embryonic cloaca, formed by the union of proc subset: emapa_ehdaa2 subset: pheno_slim synonym: "embryonic cloacal membrane" EXACT [] -synonym: "membrana cloacalis" RELATED LATIN [Wikipedia:Cloacal_membrane] +synonym: "membrana cloacalis" RELATED OMO:0003011 [Wikipedia:Cloacal_membrane] xref: EHDAA2:0000257 xref: EHDAA:214 xref: EHDAA:2933 @@ -227696,7 +228039,7 @@ def: "Groove between maxillary prominence and lateral nasal process." [http://ww comment: On the nasal surface of the body of the maxilla, in front of the opening of the sinus is a deep groove, the lacrimal groove (or lacrimal sulcus), which is converted into the nasolacrimal canal, by the lacrimal bone and inferior nasal concha; this canal opens into the inferior meatus of the nose and transmits the nasolacrimal duct[WP] See also: oblique facial cleft subset: emapa_ehdaa2 synonym: "naso-lacrimal groove" EXACT [EMAPA:16679] -synonym: "s. lacrimalis maxillae" RELATED LATIN [Wikipedia:Lacrimal_groove] +synonym: "s. lacrimalis maxillae" RELATED OMO:0003011 [Wikipedia:Lacrimal_groove] xref: EHDAA2:0001238 xref: EHDAA:4770 xref: EMAPA:16679 @@ -228145,7 +228488,7 @@ property_value: editor_note "inferred from artery" xsd:string id: UBERON:0006376 name: premacula segment of distal straight tubule namespace: uberon -def: "." [https://sourceforge.net/tracker/?func=detail&aid=3123600&group_id=76834&atid=1205376, PMID:14595018] +def: "Missing definition for term UBERON:0006376. Please replace it using linked reference." [PMID:14595018] synonym: "distal straight tubule premacula segment" EXACT [MA:0002628] synonym: "kidney medulla loop of Henle ascending limb thick segment" EXACT [MA:th] synonym: "medullary thick ascending limb of Henle's loop" EXACT [MA:th] @@ -228157,6 +228500,7 @@ is_a: UBERON:0007685 ! region of nephron tubule relationship: part_of UBERON:0001291 {source="MA"} ! thick ascending limb of loop of Henle relationship: part_of UBERON:0006541 {source="MA"} ! outer medulla inner stripe loop of Henle relationship: part_of UBERON:0006542 {source="MA"} ! outer medulla outer stripe loop of Henle +property_value: term_tracker_item "https://sourceforge.net/tracker/?func=detail&aid=3123600&group_id=76834&atid=1205376" xsd:anyURI [Term] id: UBERON:0006435 @@ -228215,7 +228559,7 @@ synonym: "fibrous ring" RELATED [BTO:0003627] xref: BTO:0003627 xref: EMAPA:32670 xref: FMA:76704 -xref: MESH:D000070616 +xref: MESH:D000070616 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} is_a: UBERON:0001995 ! fibrocartilage [Term] @@ -228536,7 +228880,7 @@ synonym: "distal urethral opening of female" RELATED [EMAPA:36453] synonym: "external orifice of female urethra" EXACT [FMA:85266] synonym: "external urethral orifice (female)" EXACT [FMA:85266] synonym: "female urethral meatus" EXACT [FMA:85266] -synonym: "ostium urethrae externum (urethra feminina)" EXACT LATIN [FMA:85266, FMA:TA] +synonym: "ostium urethrae externum (urethra feminina)" EXACT OMO:0003011 [FMA:85266, FMA:TA] synonym: "urethral meatus of clitoral urethra" EXACT [EMAPA:36453] synonym: "urethral opening of clitoral urethra" RELATED [EMAPA:36453] xref: EMAPA:36453 @@ -228652,8 +228996,8 @@ namespace: uberon def: "The pectinate line (anocutaneous line, dentate line, anorectal junction) is a line which divides the upper 2/3rds and lower 1/3rd of the anal canal. Developmentally, this line represents the hindgut-proctodeum junction. It is an important anatomical landmark, and several distinctions can be made based upon the location of a structure relative to this line:." [Wikipedia:Pectinate_line] synonym: "dentate line" RELATED [Wikipedia:Pectinate_line] synonym: "Hilton's 'white line'" RELATED [EMAPA:19159] -synonym: "linea anocutanea" RELATED LATIN [Wikipedia:Pectinate_line] -synonym: "linea pectinata canalis analis" EXACT LATIN [FMA:75383, FMA:TA] +synonym: "linea anocutanea" RELATED OMO:0003011 [Wikipedia:Pectinate_line] +synonym: "linea pectinata canalis analis" EXACT OMO:0003011 [FMA:75383, FMA:TA] synonym: "pectinate line of anal canal" EXACT [FMA:75383] synonym: "recto-anal junction" RELATED [Wikipedia:Pectinate_line] synonym: "site of anal membrane" RELATED [EMAPA:19159] @@ -228820,7 +229164,7 @@ synonym: "dentary symphysis" EXACT [TAO:0001851] synonym: "inter-dentary joint" EXACT [TAO:0001851] synonym: "inter-mandibular joint" EXACT [TAO:0001851] synonym: "mental symphysis" RELATED [Wikipedia:Symphysis_menti] -synonym: "symphysis mandibulae" RELATED LATIN [Wikipedia:Symphysis_menti] +synonym: "symphysis mandibulae" RELATED OMO:0003011 [Wikipedia:Symphysis_menti] synonym: "symphysis menti" EXACT [MA:0001490] xref: AAO:0000277 xref: FMA:75779 @@ -228848,7 +229192,7 @@ synonym: "aponeurotic" RELATED [Wikipedia:Aponeurosis] xref: AEO:0000092 xref: EHDAA2:0003092 xref: FMA:9722 -xref: MESH:D000070606 +xref: MESH:D000070606 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: NCIT:C32133 xref: SCTID:331712004 xref: UMLS:C0225205 {source="ncithesaurus:Aponeurosis"} @@ -228938,7 +229282,7 @@ synonym: "muscular coat of uterine tube" EXACT [FMA:18318] synonym: "muscular layer of uterine tube" EXACT [FMA:18318] synonym: "muscularis of uterine tube" EXACT [FMA:18318] synonym: "tunica muscularis (Tuba uterina)" EXACT [FMA:18318] -synonym: "tunica muscularis tubae uterinae" EXACT LATIN [FMA:18318, FMA:TA] +synonym: "tunica muscularis tubae uterinae" EXACT OMO:0003011 [FMA:18318, FMA:TA] synonym: "uterine tubal muscularis" EXACT [FMA:18318] xref: EMAPA:29046 xref: FMA:18318 @@ -228986,7 +229330,7 @@ synonym: "adventitia of ductus deferens" EXACT [FMA:19238] synonym: "adventitia of vas deferens" EXACT [FMA:19238] synonym: "deferent ductal adventitia" EXACT [FMA:19238] synonym: "tunica adventitia (ductus deferens)" EXACT [FMA:19238] -synonym: "tunica adventitia ductus deferentis" EXACT LATIN [FMA:19238, FMA:TA] +synonym: "tunica adventitia ductus deferentis" EXACT OMO:0003011 [FMA:19238, FMA:TA] xref: EMAPA:29767 xref: FMA:19238 xref: SCTID:299803005 @@ -229004,7 +229348,7 @@ def: "An adventitia that is part of a seminal vesicle." [OBOL:automatic] synonym: "adventitia of seminal gland" EXACT [FMA:19403] synonym: "seminal vesicle adventitia" EXACT [FMA:19403] synonym: "tunica adventitia (vesicula seminalis)" EXACT [FMA:19403] -synonym: "tunica adventitia glandulae vesiculosae" EXACT LATIN [FMA:19403, FMA:TA] +synonym: "tunica adventitia glandulae vesiculosae" EXACT OMO:0003011 [FMA:19403, FMA:TA] xref: EMAPA:29775 xref: FMA:19403 xref: SCTID:252406002 @@ -229019,7 +229363,7 @@ id: UBERON:0006652 name: muscular layer of vagina namespace: uberon synonym: "muscular coat of vagina" EXACT [FMA:19976] -synonym: "tunica muscularis vaginae" EXACT LATIN [FMA:19976, FMA:TA] +synonym: "tunica muscularis vaginae" EXACT OMO:0003011 [FMA:19976, FMA:TA] synonym: "vaginal muscularis" EXACT [] xref: EMAPA:30997 xref: FMA:19976 @@ -229061,8 +229405,8 @@ name: glenoid fossa namespace: uberon def: "Anatomical cavity for the proximal articular surface of the proximal limb or fin element with the scapulocoracoid or equivalent structure." [PHENOSCAPE:ad] subset: pheno_slim -synonym: "cavitas glenoidalis" RELATED LATIN [Wikipedia:Glenoid_cavity] -synonym: "cavitas glenoidalis scapulae" EXACT LATIN [FMA:23275, FMA:TA] +synonym: "cavitas glenoidalis" RELATED OMO:0003011 [Wikipedia:Glenoid_cavity] +synonym: "cavitas glenoidalis scapulae" EXACT OMO:0003011 [FMA:23275, FMA:TA] synonym: "cavitus glenoidalis" EXACT [FMA:23275] synonym: "glenoid cavity" EXACT [FMA:23275] synonym: "glenoid cavity" RELATED [AAO:0000749] @@ -229071,6 +229415,7 @@ synonym: "glenoid facet" EXACT [] xref: AAO:0000749 xref: EMAPA:25122 xref: FMA:23275 +xref: MESH:D061165 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} xref: NCIT:C32682 xref: SCTID:181914008 xref: UMLS:C1261046 {source="ncithesaurus:Glenoid_Fossa"} @@ -229117,7 +229462,7 @@ synonym: "muscularis layer" EXACT [FMA:45634] synonym: "muscularis propria" RELATED [Wikipedia:Muscularis_externa] synonym: "transverse muscular fibers" RELATED [Wikipedia:Muscularis_externa] synonym: "tunica externa" RELATED [BTO:0004838] -synonym: "tunica muscularis" EXACT LATIN [BTO:0004838] +synonym: "tunica muscularis" EXACT OMO:0003011 [BTO:0004838] synonym: "tunica muscularis" RELATED [Wikipedia:Muscularis_externa] xref: BTO:0004838 xref: SCTID:86915006 @@ -229137,7 +229482,7 @@ id: UBERON:0006661 name: epicranial aponeurosis namespace: uberon def: "The galea aponeurotica (epicranial aponeurosis, aponeurosis epicranialis) is a tough layer of dense fibrous tissue which covers the upper part of the cranium; behind, it is attached, in the interval between its union with the Occipitales, to the external occipital protuberance and highest nuchal lines of the occipital bone; in front, it forms a short and narrow prolongation between its union with the Frontales. On either side it gives origin to the Auriculares anterior and superior; in this situation it loses its aponeurotic character, and is continued over the temporal fascia to the zygomatic arch as a layer of laminated areolar tissue. It is closely connected to the integument by the firm, dense, fibro-fatty layer which forms the superficial fascia of the scalp: it is attached to the pericranium by loose cellular tissue, which allows the aponeurosis, carrying with it the integument to move through a considerable distance." [Wikipedia:Galea_aponeurotica] -synonym: "aponeurosis epicranialis" EXACT LATIN [FMA:46768, FMA:TA] +synonym: "aponeurosis epicranialis" EXACT OMO:0003011 [FMA:46768, FMA:TA] synonym: "aponeurosis of epicranius" EXACT [FMA:46768] synonym: "cranial aponeurosis" RELATED [Wikipedia:Galea_aponeurotica] synonym: "epicranial aponeurosis" EXACT [FMA:46768] @@ -229145,7 +229490,7 @@ synonym: "epicranial aponeurosis" RELATED [Wikipedia:Galea_aponeurotica] synonym: "epicranius aponeurosis" EXACT [FMA:46768] synonym: "galea aponeurosis" RELATED [Wikipedia:Galea_aponeurotica] synonym: "galea aponeurotica" EXACT [FMA:46768] -synonym: "galea aponeurotica; aponeurosis epicranialis" RELATED LATIN [Wikipedia:Galea_aponeurotica] +synonym: "galea aponeurotica; aponeurosis epicranialis" RELATED OMO:0003011 [Wikipedia:Galea_aponeurotica] synonym: "galeal aponeurosis" RELATED [Wikipedia:Galea_aponeurotica] xref: EMAPA:19210 xref: FMA:46768 @@ -229160,7 +229505,7 @@ id: UBERON:0006668 name: carotid canal namespace: uberon def: "On the interior surface of the temporal bone, behind the rough surface of the apex, is the large circular aperture of the carotid canal, which ascends at first vertically, and then, making a bend, runs horizontally forward and medialward. It transmits into the cranium, the internal carotid artery, and the carotid plexus of nerves. Sympathetics to the head also pass through the carotid canal. They have several motor functions: raise the eyelid (superior tarsal muscle), dilate pupil, innervate sweat glands of face and scalp and constricts blood vessels in head[WP]." [Wikipedia:Carotid_canal] -synonym: "canalis caroticus" RELATED LATIN [Wikipedia:Carotid_canal] +synonym: "canalis caroticus" RELATED OMO:0003011 [Wikipedia:Carotid_canal] xref: EMAPA:18707 xref: FMA:55805 xref: Wikipedia:Carotid_canal @@ -229179,7 +229524,7 @@ def: "The three-lobed cloverleaf-shaped aponeurosis situated at the center of th subset: pheno_slim synonym: "central tendon" EXACT [FMA:58279] synonym: "centrum tendineum" EXACT [FMA:58279] -synonym: "centrum tendineum diaphragmatis" EXACT LATIN [FMA:58279, FMA:TA] +synonym: "centrum tendineum diaphragmatis" EXACT OMO:0003011 [FMA:58279, FMA:TA] xref: EMAPA:17702 xref: FMA:58279 xref: NCIT:C34119 @@ -229202,7 +229547,7 @@ namespace: uberon def: "A valve that is part of a vein." [OBOL:automatic] synonym: "valve of vein" EXACT [FMA:68095] xref: FMA:68095 -xref: MESH:D055422 +xref: MESH:D055422 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} is_a: UBERON:0003978 ! valve intersection_of: UBERON:0003978 ! valve intersection_of: part_of UBERON:0001638 ! vein @@ -229226,7 +229571,7 @@ name: hypoglossal canal namespace: uberon def: "The hypoglossal canal is a bony canal in the occipital bone of the skull." [Wikipedia:Hypoglossal_canal] synonym: "anterior condylar canal" RELATED [EMAPA:19012] -synonym: "canalis nervi hypoglossi" RELATED LATIN [Wikipedia:Hypoglossal_canal] +synonym: "canalis nervi hypoglossi" RELATED OMO:0003011 [Wikipedia:Hypoglossal_canal] synonym: "hyperglossal canal" RELATED [Wikipedia:Hypoglossal_canal] xref: EMAPA:19012 xref: FMA:75370 @@ -229245,7 +229590,7 @@ name: spinal vein namespace: uberon def: "A vein that is part of a vertebral column." [OBOL:automatic] synonym: "spinal branch" RELATED [FMA:76735] -synonym: "vena spinalis" EXACT LATIN [FMA:76735, FMA:TA] +synonym: "vena spinalis" EXACT OMO:0003011 [FMA:76735, FMA:TA] xref: EMAPA:18255 xref: FMA:76735 xref: MA:0002108 @@ -229262,7 +229607,7 @@ name: vertebral canal namespace: uberon def: "A conduit enclosed within the vertebral foramen of the vertebrae through which the spinal cord passes." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Spinal_canal] subset: pheno_slim -synonym: "c. vertebralis" RELATED LATIN [Wikipedia:Spinal_canal] +synonym: "c. vertebralis" RELATED OMO:0003011 [Wikipedia:Spinal_canal] synonym: "foramen vertebrale" RELATED [AAO:0000693] synonym: "neural canal" RELATED [AAO:0000693] synonym: "spinal canal" RELATED [AAO:0000693] @@ -229271,6 +229616,7 @@ synonym: "vertebral canal" RELATED [Wikipedia:Spinal_canal] xref: AAO:0000693 xref: FMA:9680 xref: GAID:242 +xref: MESH:D013115 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} xref: NCIT:C33869 xref: NCIT:C34221 xref: SCTID:361746009 @@ -229352,7 +229698,7 @@ subset: pheno_slim synonym: "cochlea modiolus" EXACT [FMA:61278] synonym: "columella cochleae" RELATED [BTO:0001693] synonym: "modiolus" BROAD [MA:0001182] -synonym: "modiolus cochleae" EXACT LATIN [FMA:61278, FMA:TA] +synonym: "modiolus cochleae" EXACT OMO:0003011 [FMA:61278, FMA:TA] synonym: "modiolus of cochlea" EXACT [FMA:61278] xref: BTO:0001693 xref: EMAPA:35575 @@ -229374,8 +229720,8 @@ namespace: uberon alt_id: UBERON:0028186 def: "A spiral thickening of the fibrous lining of the cochlear wall. Spiral ligament secures the membranous cochlear duct to the bony spiral canal of the cochlea. Its spiral ligament fibrocytes function in conjunction with the stria vascularis to mediate cochlear ion homeostasis." [https://github.com/obophenotype/mouse-anatomy-ontology/issues/71, Wikipedia:Spiral_ligament] subset: pheno_slim -synonym: "ligamentum spirale ductus cochlearis" EXACT LATIN [Wikipedia:Spiral_ligament] -synonym: "spiral cochlear ligament" EXACT LATIN [] +synonym: "ligamentum spirale ductus cochlearis" EXACT OMO:0003011 [Wikipedia:Spiral_ligament] +synonym: "spiral cochlear ligament" EXACT OMO:0003011 [] synonym: "spiral ligament of cochlea" EXACT [BIRNLEX:2524] synonym: "spiral ligament of cochlear duct" EXACT [FMA:77834] xref: BIRNLEX:2524 @@ -229422,7 +229768,7 @@ def: "During the third week there appears, immediately behind the ventral ends o synonym: "lateral lingual prominence" RELATED [] synonym: "lateral swellings" RELATED [Wikipedia:Lateral_lingual_swelling] synonym: "tuberculum laterale" RELATED [Wikipedia:Lateral_lingual_swelling] -synonym: "tuberculum linguale laterale" RELATED LATIN [Wikipedia:Lateral_lingual_swelling] +synonym: "tuberculum linguale laterale" RELATED OMO:0003011 [Wikipedia:Lateral_lingual_swelling] xref: EHDAA2:0000911 xref: EMAPA:17189 xref: FMA:313628 @@ -229449,8 +229795,8 @@ synonym: "cornea limbus" EXACT [] synonym: "corneal limbus" EXACT [FMA:58342, GAID:896] synonym: "corneal-scleral limbus" EXACT [PMID:17051547] synonym: "corneoscleral junction" EXACT [GAID:896] -synonym: "limbus corneae" EXACT LATIN [Wikipedia:Corneal_limbus] -synonym: "limbus corneae" RELATED LATIN [Wikipedia:Corneal_limbus] +synonym: "limbus corneae" EXACT OMO:0003011 [Wikipedia:Corneal_limbus] +synonym: "limbus corneae" RELATED OMO:0003011 [Wikipedia:Corneal_limbus] synonym: "sclerocorneal junction" EXACT [FMA:58342] synonym: "sclerocorneal limbus" EXACT [GAID:896] xref: EFO:0001403 @@ -229561,7 +229907,7 @@ name: lumen of open tracheal system trachea namespace: uberon def: "An anatomical space that surrounded_by a open tracheal system trachea." [OBOL:automatic] synonym: "tracheal lumen" BROAD SENSU [FBbt:00007410] -xref: FBbt:00007410 +xref: FBbt:00007410 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0000464 ! anatomical space intersection_of: UBERON:0000464 ! anatomical space intersection_of: luminal_space_of UBERON:0003127 ! open tracheal system trachea @@ -229590,6 +229936,7 @@ namespace: uberon def: "A subdivision of a the reproductive tract in a female organism that is the site of embryo development." [http://orcid.org/0000-0002-6601-2165] subset: grouping_class synonym: "uterus" BROAD SENSU [FBbt:00004924] +xref: FBbt:00004924 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: TADS:0000421 xref: WBbt:0006760 is_a: UBERON:0005156 ! reproductive structure @@ -229742,7 +230089,6 @@ relationship: part_of UBERON:0001225 {source="MA"} ! cortex of kidney id: UBERON:0006854 name: distal straight tubule postmacula segment namespace: uberon -def: "." [https://sourceforge.net/tracker/?func=detail&aid=3123598&group_id=76834&atid=1205376] synonym: "cortical thick ascending limb of Henle's loop" EXACT [MA:th] synonym: "kidney cortex loop of Henle ascending limb thick segment" EXACT [MA:th] synonym: "renal cortex loop of Henle ascending limb thick segment" EXACT [MA:th] @@ -229752,6 +230098,7 @@ xref: MA:0002615 is_a: UBERON:0006853 ! renal cortex tubule relationship: part_of UBERON:0001291 {source="MA"} ! thick ascending limb of loop of Henle relationship: part_of UBERON:0006853 {source="MA"} ! renal cortex tubule +property_value: term_tracker_item "https://sourceforge.net/tracker/?func=detail&aid=3123598&group_id=76834&atid=1205376" xsd:anyURI [Term] id: UBERON:0006855 @@ -229761,8 +230108,8 @@ def: "A muscular coat that is part of a ureter." [OBOL:automatic] synonym: "muscular coat of ureter" EXACT [FMA:15893] synonym: "muscular layer of ureter" EXACT [FMA:15893] synonym: "muscularis of ureter" EXACT [FMA:15893] -synonym: "tunica muscularis (ureter)" EXACT LATIN [FMA:TA] -synonym: "tunica muscularis ureteris" EXACT LATIN [FMA:TA] +synonym: "tunica muscularis (ureter)" EXACT OMO:0003011 [FMA:TA] +synonym: "tunica muscularis ureteris" EXACT OMO:0003011 [FMA:TA] synonym: "ureteral smooth muscle layer" RELATED [EMAPA:28567] xref: EMAPA:28811 xref: FMA:15893 @@ -229818,7 +230165,7 @@ namespace: uberon def: "A diaphysis that is part of a femur[Automatically generated definition]." [OBOL:automatic, Wikipedia:Body_of_femur] subset: pheno_slim synonym: "body of femur" EXACT [FMA:32847] -synonym: "corpus femoris" EXACT LATIN [FMA:32847, FMA:TA] +synonym: "corpus femoris" EXACT OMO:0003011 [FMA:32847, FMA:TA] synonym: "femoral diaphysis" EXACT [FMA:32847] synonym: "femoral shaft" EXACT [] synonym: "shaft of femur" EXACT [FMA:32847] @@ -229870,7 +230217,7 @@ def: "The distalmost portion of the digestive tract, derived from the hindgut, a synonym: "rectal part of digestive tract" RELATED [] synonym: "rectum" NARROW [FBbt:00005756] synonym: "terminal section of digestive tract" RELATED [] -xref: FBbt:00005756 +xref: FBbt:00005756 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: WBbt:0005773 is_a: UBERON:0004921 ! subdivision of digestive tract relationship: continuous_with UBERON:0001245 ! anus @@ -229884,7 +230231,7 @@ namespace: uberon def: "A gland that secretes a seminal fluid." [OBOL:automatic] subset: grouping_class subset: organ_slim -xref: FBbt:00004958 +xref: FBbt:00004958 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: WBbt:0006870 is_a: UBERON:0005399 ! male reproductive gland intersection_of: UBERON:0002530 ! gland @@ -230402,7 +230749,7 @@ name: efferent duct namespace: uberon def: "The efferent ducts (or efferent ductules or ductuli efferentes) connect the rete testis with the initial section of the epididymis. The ductuli are unilaminar and composed of columnar ciliated and non-ciliated (absorptive) cells. The ciliated cells serve to stir the luminal fluids, possibly to help ensure homogeneous absorption of water from the fluid produced by the testis, which results in an increase in the concentration of luminal sperm. The epithelium is surrounded by a band of smooth muscle that helps to propel the sperm toward the epididymis." [Wikipedia:Efferent_ducts] subset: pheno_slim -synonym: "ductuli efferentes testis" RELATED LATIN [Wikipedia:Efferent_ducts] +synonym: "ductuli efferentes testis" RELATED OMO:0003011 [Wikipedia:Efferent_ducts] synonym: "efferent ductule" EXACT [FMA:19081, Wikipedia:Efferent_ducts] synonym: "seminal duct" EXACT [] synonym: "vasa efferentia" RELATED [AAO:0010532, Wikipedia:Efferent_ducts] @@ -230519,7 +230866,7 @@ synonym: "ovarian stroma" EXACT [FMA:18626] synonym: "ovary stroma" EXACT [MA:0002991] synonym: "stroma of the ovary" EXACT [Wikipedia:Stroma_of_ovary] synonym: "stroma ovarica" EXACT [FMA:18626] -synonym: "stroma ovarii" RELATED LATIN [Wikipedia:Stroma_of_ovary] +synonym: "stroma ovarii" RELATED OMO:0003011 [Wikipedia:Stroma_of_ovary] xref: CALOHA:TS-1246 xref: EMAPA:28880 xref: FMA:18626 @@ -230549,10 +230896,10 @@ synonym: "distal part of the hypophysis" RELATED [NeuroNames:410] synonym: "pars anterior" BROAD [EHDAA2:0001416, MA:0000854, ZFA:0001195] synonym: "pars anterior of adenohypophysis" EXACT [FMA:74630] synonym: "pars distalis" RELATED [MA:0000854] -synonym: "pars distalis (glandula pituitaria)" EXACT LATIN [FMA:74630, FMA:TA] -synonym: "pars distalis (hypophysis)" RELATED LATIN [NeuroNames:410] +synonym: "pars distalis (glandula pituitaria)" EXACT OMO:0003011 [FMA:74630, FMA:TA] +synonym: "pars distalis (hypophysis)" RELATED OMO:0003011 [NeuroNames:410] synonym: "pars distalis adenohypophyseos" RELATED [BTO:0001787] -synonym: "pars distalis adenohypophysis" EXACT LATIN [FMA:74630, FMA:TA] +synonym: "pars distalis adenohypophysis" EXACT OMO:0003011 [FMA:74630, FMA:TA] synonym: "pars distalis lobi anterioris hypophyseos" RELATED [BTO:0001787] synonym: "pars distalis of anterior lobe of pituitary gland" EXACT [FMA:74630] synonym: "pars glandularis" RELATED [MA:0000854] @@ -230691,7 +231038,7 @@ def: "A multicellular organism that existence_ends_with a post-juvenile adult st synonym: "adult" BROAD [] synonym: "adults" EXACT OMO:0003004 [TAO:0002046] xref: BILA:0000078 -xref: FBbt:00003004 +xref: FBbt:00003004 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: galen:Adult xref: HAO:0000087 xref: http://neurolex.org/wiki/Category\:Adult_organism @@ -230822,7 +231169,7 @@ namespace: uberon def: "The femur neck or neck of the femur is a flattened pyramidal process of bone, connecting the femoral head with the femoral shaft, and forming with the latter a wide angle opening medialward." [Wikipedia:Femur_neck] subset: human_reference_atlas subset: pheno_slim -synonym: "collum femoris" RELATED LATIN [Wikipedia:Femur_neck] +synonym: "collum femoris" RELATED OMO:0003011 [Wikipedia:Femur_neck] synonym: "femoral neck" EXACT [FMA:42385] synonym: "femur neck" RELATED [Wikipedia:Femur_neck] synonym: "neck of the femur" RELATED [Wikipedia:Femur_neck] @@ -231216,7 +231563,7 @@ synonym: "axillary border of scapula" EXACT [FMA:23239] synonym: "lateral border of scapula" EXACT [FMA:23239] synonym: "lateral part of scapula" RELATED [FMA:23239] synonym: "margo lateralis (scapula)" EXACT [FMA:23239] -synonym: "margo lateralis scapulae" EXACT LATIN [FMA:23239, FMA:TA] +synonym: "margo lateralis scapulae" EXACT OMO:0003011 [FMA:23239, FMA:TA] xref: EMAPA:25126 xref: FMA:23239 xref: Wikipedia:Lateral_border_of_the_scapula @@ -231231,7 +231578,7 @@ namespace: uberon def: "The medial border of the scapula (vertebral border, medial margin) is the longest of the three borders, and extends from the medial to the inferior angle. It is arched, intermediate in thickness between the superior and the axillary borders, and the portion of it above the spine forms an obtuse angle with the part below. This border presents an anterior and a posterior lip, and an intermediate narrow area. The anterior lip affords attachment to the Serratus anterior; the posterior lip, to the Supraspinatus above the spine, the Infraspinatus below; the area between the two lips, to the Levator scapulC& above the triangular surface at the commencement of the spine, to the Rhomboideus minor on the edge of that surface, and to the Rhomboideus major below it; this last is attached by means of a fibrous arch, connected above to the lower part of the triangular surface at the base of the spine, and below to the lower part of the border." [Wikipedia:Medial_border_of_scapula] subset: human_reference_atlas synonym: "margo medialis (scapula)" EXACT [FMA:23242] -synonym: "margo medialis scapulae" EXACT LATIN [FMA:23242, FMA:TA] +synonym: "margo medialis scapulae" EXACT OMO:0003011 [FMA:23242, FMA:TA] synonym: "medial border of the scapula" RELATED [Wikipedia:Medial_border_of_scapula] synonym: "medial margin of the scapula" RELATED [Wikipedia:Medial_border_of_scapula] synonym: "medial part of scapula" EXACT [FMA:23242] @@ -231254,7 +231601,7 @@ namespace: uberon def: "An angle of the scapula formed by the union of the vertebral and axillary borders; its dorsal surface affords attachment to the Teres major and frequently to a few fibers of the Latissimus dorsi.[WP,unvetted]." [Wikipedia:Inferior_angle_of_scapula] subset: human_reference_atlas synonym: "angulus inferior (scapula)" EXACT [FMA:13315] -synonym: "angulus inferior scapulae" EXACT LATIN [Wikipedia:Inferior_angle_of_scapula] +synonym: "angulus inferior scapulae" EXACT OMO:0003011 [Wikipedia:Inferior_angle_of_scapula] xref: EMAPA:25128 xref: FMA:13315 xref: Wikipedia:Inferior_angle_of_scapula @@ -231359,7 +231706,7 @@ def: "The structure from the trachea, bronchi, and bronchioles that forms the ai subset: human_reference_atlas subset: organ_slim subset: pheno_slim -synonym: "arbor tracheobronchialis" EXACT LATIN [FMA:7393, FMA:TA] +synonym: "arbor tracheobronchialis" EXACT OMO:0003011 [FMA:7393, FMA:TA] synonym: "tracheobronchial system" RELATED [HP:0005607] xref: FMA:7393 xref: NCIT:C117875 @@ -231670,6 +232017,7 @@ namespace: uberon def: "A nucleus of brain that is part of a preoptic area." [OBOL:automatic] xref: CALOHA:TS-0822 xref: EV:0100226 +xref: MESH:D011301 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} is_a: UBERON:0006569 ! diencephalic nucleus intersection_of: UBERON:0002308 ! nucleus of brain intersection_of: part_of UBERON:0001928 ! preoptic area @@ -232139,13 +232487,13 @@ subset: human_reference_atlas subset: pheno_slim subset: vertebrate_core synonym: "duct of pancreas" EXACT [OBOL:accepted] -synonym: "ductus pancreaticus" RELATED LATIN [Wikipedia:Pancreatic_duct] +synonym: "ductus pancreaticus" RELATED OMO:0003011 [Wikipedia:Pancreatic_duct] synonym: "pancreas duct" EXACT [OBOL:accepted] xref: EHDAA:9194 xref: EMAPA:32952 xref: FMA:10419 xref: MA:0000124 -xref: MESH:D010183 +xref: MESH:D010183 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: SCTID:181278006 xref: TAO:0001372 xref: VHOG:0000254 @@ -232237,7 +232585,7 @@ synonym: "outer epidermal layer" EXACT [] synonym: "outer epithelial layer" EXACT [] xref: BSA:0000073 xref: BTO:0000313 -xref: FBbt:00004993 +xref: FBbt:00004993 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: HAO:0000298 xref: TADS:0000109 xref: WBbt:0005733 @@ -232717,7 +233065,7 @@ name: hippocampus stratum lucidum namespace: uberon def: "Layer of hippocampus area CA3 lying superficial to the pyramidal cell layer that contains mossy fiber axons projecting from the dentate gyrus. A slight thickening in this layer marks the border in some species between areas CA2 and CA3. dapted from Paxinos, G. The rat central nervous system, 2nd ed, Academic Press, San Diego, 1995, pg. 460)." [BIRNLEX:4108] synonym: "stratum lucidum" BROAD [BIRNLEX:4108] -synonym: "stratum lucidum hippocampi" RELATED LATIN [Wikipedia:Stratum_lucidum_of_hippocampus] +synonym: "stratum lucidum hippocampi" RELATED OMO:0003011 [Wikipedia:Stratum_lucidum_of_hippocampus] synonym: "stratum lucidum hippocampus" RELATED [BAMS:SLu] xref: BAMS:SLu xref: BIRNLEX:4108 @@ -232742,7 +233090,7 @@ name: hippocampus alveus namespace: uberon def: "Regional part of fornix consisting of a thin layer of white matter on the surface of the hippocampal formation, bordering the wall of the lateral ventricle and composed of white, myelinated fibers. The alveus arises from cell bodies in the subiculum and hippocampus, and eventually merges with the fimbria of the hippocampus. The fimbria goes on to become the fornix (MM: 2006-10-26)." [BIRNLEX:1510] synonym: "alveus" EXACT [BIRNLEX:1510] -synonym: "alveus hippocampi" RELATED LATIN [NeuroNames:186] +synonym: "alveus hippocampi" RELATED OMO:0003011 [NeuroNames:186] synonym: "alveus of fornix" RELATED [BAMS:alv] synonym: "alveus of hippocampus" EXACT [FMA:83867] synonym: "alveus of the hippocampus" RELATED [BAMS:alv] @@ -232770,7 +233118,7 @@ id: UBERON:0007641 name: trigeminal nuclear complex namespace: uberon def: "The sensory trigeminal nerve nuclei are the largest of the cranial nerve nuclei, and extend through the whole of the midbrain, pons and medulla. There is also a distinct trigeminal motor nucleus that is medial to the chief sensory nucleus[WP]." [Wikipedia:Trigeminal_nerve_nuclei] -synonym: "nuclei trigemini" RELATED LATIN [Wikipedia:Trigeminal_nerve_nuclei] +synonym: "nuclei trigemini" RELATED OMO:0003011 [Wikipedia:Trigeminal_nerve_nuclei] synonym: "trigeminal nuclei" EXACT [FMA:71248] xref: BIRNLEX:4096 xref: BM:V @@ -232778,6 +233126,7 @@ xref: CALOHA:TS-2077 xref: DHBA:266441713 xref: FMA:71248 xref: HBA:9203 +xref: MESH:D014278 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} xref: neuronames:2021 xref: UMLS:C0040999 {source="BIRNLEX:4096"} xref: Wikipedia:Trigeminal_nerve_nuclei @@ -232930,7 +233279,7 @@ synonym: "organ field" RELATED [] xref: AEO:0000170 xref: EFO:0001649 xref: EHDAA2:0003170 -xref: FBbt:00005426 +xref: FBbt:00005426 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: Wikipedia:Anlage_(biology) is_a: UBERON:0000479 {source="FBbt"} ! tissue is_a: UBERON:0005423 {source="AEO", source="FBbt"} ! developing anatomical structure @@ -232940,8 +233289,8 @@ id: UBERON:0007689 name: thyroid diverticulum namespace: uberon def: "Endodermal bud derived from the endodermal epithelium of the embryonic pharyngeal floor[MP]. The thyroid diverticulum is the embryological structure from which thyroid follicular cells derive. It grows from the floor of the pharnyx[WP]." [MP:0004662, Wikipedia:Thyroid_diverticulum] -synonym: "diverticulum thyroideum" RELATED LATIN [Wikipedia:Thyroid_diverticulum] -synonym: "saccus thyroideus" RELATED LATIN [Wikipedia:Thyroid_diverticulum] +synonym: "diverticulum thyroideum" RELATED OMO:0003011 [Wikipedia:Thyroid_diverticulum] +synonym: "saccus thyroideus" RELATED OMO:0003011 [Wikipedia:Thyroid_diverticulum] xref: Wikipedia:Thyroid_diverticulum is_a: UBERON:0001048 ! primordium relationship: part_of UBERON:0001042 {source="VHOG"} ! chordate pharynx @@ -232951,7 +233300,6 @@ relationship: transformation_of UBERON:0003091 ! thyroid primordium id: UBERON:0007690 name: early pharyngeal endoderm namespace: uberon -def: "." [http://dev.biologists.org/content/128/22/4573.full] comment: relation conflict: ZFA vs EHDAA2. Note EHDAA2 term renamed to 'early PA endoderm' subset: efo_slim synonym: "early pharyngeal arch endoderm" EXACT [EHDAA2:0001457] @@ -232968,6 +233316,7 @@ xref: ZFA:0001104 is_a: UBERON:0003258 ! endoderm of foregut is_a: UBERON:0005291 ! embryonic tissue relationship: part_of UBERON:0009722 {source="cjm"} ! entire pharyngeal arch endoderm +property_value: seeAlso "http://dev.biologists.org/content/128/22/4573.full" xsd:anyURI [Term] id: UBERON:0007691 @@ -233424,7 +233773,7 @@ namespace: uberon def: "A subdivision of a limb or fin skeleton consisting of bones which connects the upper limb or fin to the axial skeleton on each side. It consists of the clavicle and scapula in humans and, in those species with three bones in the pectoral girdle, the coracoid. Some mammalian species (e.g. the dog and the horse) have only the scapula. In humans, the only joints between the shoulder girdle and axial skeleton are the sternoclavicular joints on each side. No joint exists between each scapula and the rib cage; instead the muscular connection between the two permits relatively great mobility of the shoulder girdle in relation to the pelvic girdle. In those species having only the scapula, no joint exists between the forelimb and the thorax, the only attachment being muscular[WP]. Examples: There are only two instances, right and left pectoral girdle skeletons." [Wikipedia:Pectoral_girdle] subset: efo_slim subset: vertebrate_core -synonym: "cingulum pectorale" RELATED LATIN [Wikipedia:Pectoral_girdle] +synonym: "cingulum pectorale" RELATED OMO:0003011 [Wikipedia:Pectoral_girdle] synonym: "pectoral girdle" RELATED INCONSISTENT [VSAO:0000156] synonym: "scapular girdle" RELATED [TAO:0000407] synonym: "skeletal parts of pectoral girdle" EXACT [https://orcid.org/0000-0002-6601-2165] @@ -233633,7 +233982,7 @@ name: irregular bone namespace: uberon def: "The irregular bones are bones which, from their peculiar form, cannot be grouped as long bone, short bone, flat bone or sesamoid bone. Irregular bones serve various purposes in the body, such as protection of nervous tissue, affording multiple anchor points for skeletal muscle attachment (as with the sacrum), and maintaining pharynx and trachea support, and tongue attachment (such as the hyoid bone). They consist of cancellous tissue enclosed within a thin layer of compact bone. The irregular bones are: the vertebrC&, sacrum, coccyx, temporal, sphenoid, ethmoid, zygomatic, maxilla, mandible, palatine, inferior nasal concha, and hyoid." [Wikipedia:Irregular_bone] synonym: "os irregulare" EXACT [] -synonym: "os irregulare" RELATED LATIN [Wikipedia:Irregular_bone] +synonym: "os irregulare" RELATED OMO:0003011 [Wikipedia:Irregular_bone] xref: FMA:7477 xref: NCIT:C32881 xref: SCTID:421560006 @@ -233709,7 +234058,7 @@ name: nail plate namespace: uberon def: "The nail plate is the hard and translucent portion of the nail, composed of keratin." [https://github.com/obophenotype/uberon/issues/20, https://sourceforge.net/p/geneontology/ontology-requests/8479/, Wikipedia:Nail_plate] subset: human_reference_atlas -synonym: "lamina unguis" RELATED LATIN [Wikipedia:Nail_plate] +synonym: "lamina unguis" RELATED OMO:0003011 [Wikipedia:Nail_plate] xref: EMAPA:35583 xref: MA:0002708 xref: NCIT:C34216 @@ -233743,7 +234092,7 @@ id: UBERON:0008203 name: pelvic cavity namespace: uberon def: "The part of the ventral body cavity that is within the pelvis." [UBERON:cjm] -synonym: "cavitas pelvis" RELATED LATIN [Wikipedia:Pelvic_cavity] +synonym: "cavitas pelvis" RELATED OMO:0003011 [Wikipedia:Pelvic_cavity] synonym: "space of pelvic compartment" EXACT [FMA:9738] xref: EMAPA:37235 {source="MA:th"} xref: FMA:9738 @@ -233843,7 +234192,7 @@ synonym: "alveolar periosteum" RELATED [BTO:0001020] synonym: "alveolodental ligament" RELATED [BTO:0001020] synonym: "alveolodental membrane" RELATED [BTO:0001020] synonym: "desmodontium" RELATED [BTO:0001020, http://www.drugs.com/dict/desmodentium.html] -synonym: "fibra periodontalis" EXACT LATIN [Wikipedia:Periodontal_ligament] +synonym: "fibra periodontalis" EXACT OMO:0003011 [Wikipedia:Periodontal_ligament] synonym: "odontoperiosteum" RELATED [BTO:0001020] synonym: "paradentium" RELATED [BTO:0001020] synonym: "PDL" RELATED [Wikipedia:Periodontal_ligament] @@ -233855,8 +234204,8 @@ synonym: "peridontal ligament fiber" RELATED [http://www.drugs.com/dict/desmoden synonym: "peridontal ligament fibre" RELATED [http://www.drugs.com/dict/desmodentium.html] synonym: "peridontal membrane" RELATED [BTO:0001020] synonym: "peridontium" RELATED [BTO:0001020] -synonym: "periodontal fiber" EXACT LATIN [Wikipedia:Periodontal_ligament] -synonym: "periodontal fibre" EXACT LATIN [Wikipedia:Periodontal_ligament] +synonym: "periodontal fiber" EXACT OMO:0003011 [Wikipedia:Periodontal_ligament] +synonym: "periodontal fibre" EXACT OMO:0003011 [Wikipedia:Periodontal_ligament] synonym: "periodontium" RELATED INCONSISTENT [FMA:56665] xref: BTO:0001020 xref: CALOHA:TS-0763 @@ -233864,7 +234213,7 @@ xref: EMAPA:35679 xref: FMA:56665 xref: GAID:1259 xref: MA:0002467 -xref: MESH:D010513 +xref: MESH:D010513 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: SCTID:245775004 xref: Wikipedia:Periodontal_fiber is_a: UBERON:0008846 {source="FMA-moved"} ! skeletal ligament @@ -233974,11 +234323,11 @@ namespace: uberon def: "The sole is the bottom of the foot." [Wikipedia:Sole_(foot)] subset: pheno_slim synonym: "pelma" RELATED [Wikipedia:Sole_(foot)] -synonym: "planta" EXACT LATIN [FMA:TA] -synonym: "planta" RELATED LATIN [Wikipedia:Sole_(foot)] +synonym: "planta" EXACT OMO:0003011 [FMA:TA] +synonym: "planta" RELATED OMO:0003011 [Wikipedia:Sole_(foot)] synonym: "plantar part of foot" EXACT [FMA:25000] synonym: "plantar region" EXACT [FMA:25000] -synonym: "regio plantaris" EXACT LATIN [FMA:TA] +synonym: "regio plantaris" EXACT OMO:0003011 [FMA:TA] synonym: "sole" EXACT [FMA:25000] synonym: "sole of foot" EXACT [FMA:25000] synonym: "sole of foot" RELATED [Wikipedia:Sole_(foot)] @@ -234218,7 +234567,7 @@ name: intertarsal joint namespace: uberon def: "Intertarsal articulations are the joints of the tarsus. The specific intertarsal articulations are: Talocalcaneal articulation Talocalcaneonavicular articulation Calcaneocuboid articulation Cuneonavicular articulation Cuboideonavicular articulation Intercuneiform articulation Cuneocuboid articulation." [Wikipedia:Intertarsal_articulations] synonym: "articulationes intertarsale" RELATED [MESH:A02.835.583.378.831] -synonym: "articulationes intertarsales" RELATED LATIN [Wikipedia:Intertarsal_articulations] +synonym: "articulationes intertarsales" RELATED OMO:0003011 [Wikipedia:Intertarsal_articulations] synonym: "articulationes intertarseae" RELATED [MESH:A02.835.583.378.831] synonym: "intermetatarsal joint" RELATED [MESH:A02.835.583.378.831] synonym: "intertarsal" RELATED [Wikipedia:Intertarsal_articulations] @@ -234311,7 +234660,7 @@ name: proximal epiphysis of fibula namespace: uberon def: "A proximal epiphysis that is part of a fibula." [OBOL:automatic] subset: pheno_slim -synonym: "caput fibulae" EXACT LATIN [Wikipedia:Head_of_fibula] +synonym: "caput fibulae" EXACT OMO:0003011 [Wikipedia:Head_of_fibula] synonym: "fibular head" RELATED [FMA:33729] synonym: "head of fibula" EXACT [FMA:33729] synonym: "proximal end of fibula" EXACT [FMA:33729] @@ -234357,7 +234706,7 @@ namespace: uberon def: "The dorsal venous arch of the foot is a superficial vein that connects the small saphenous vein and the great saphenous vein. Anatomically, it is defined by where the dorsal veins of the first and fifth digit, respectively, meet the great saphenous vein and small saphenous vein." [Wikipedia:Dorsal_venous_arch_of_the_foot] subset: human_reference_atlas synonym: "arcus venosus dorsalis pedis" EXACT [Wikipedia:Dorsal_venous_arch_of_the_foot] -synonym: "arcus venosus dorsalis pedis" RELATED LATIN [Wikipedia:Dorsal_venous_arch_of_the_foot] +synonym: "arcus venosus dorsalis pedis" RELATED OMO:0003011 [Wikipedia:Dorsal_venous_arch_of_the_foot] synonym: "dorsal venous arch of foot" EXACT [FMA:44356] xref: EMAPA:37521 {source="MA:th"} xref: FMA:44356 @@ -234419,8 +234768,8 @@ name: gingival groove namespace: uberon def: "The gingival sulcus is an area of potential space between a tooth and the surrounding gingival tissue and is lined by sulcular epithelium. The depth of the sulcus (Latin for groove) is bounded by two entities: apically by the gingival fibers of the connective tissue attachment and coronally by the free gingival margin." [Wikipedia:Gingival_sulcus] synonym: "gingival sulcus" EXACT [FMA:74580] -synonym: "sulcus gingivalis" EXACT LATIN [FMA:TA] -synonym: "sulcus gingivalis" RELATED LATIN [Wikipedia:Gingival_sulcus] +synonym: "sulcus gingivalis" EXACT OMO:0003011 [FMA:TA] +synonym: "sulcus gingivalis" RELATED OMO:0003011 [Wikipedia:Gingival_sulcus] synonym: "tooth-gingiva interface" EXACT [] xref: FMA:74580 xref: NCIT:C114645 @@ -234447,7 +234796,7 @@ synonym: "aedeagus" NARROW SENSU [FBbt:00004850] synonym: "copulatory organ" RELATED [] synonym: "penis" NARROW [] xref: AAO:0010255 -xref: FBbt:00004850 +xref: FBbt:00004850 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: HAO:0000091 xref: TAO:0002036 xref: TGMA:0000585 @@ -234487,7 +234836,7 @@ namespace: uberon def: "A head that is part of a embryo." [OBOL:automatic] subset: non_informative xref: CALOHA:TS-0246 -xref: FBbt:00000155 +xref: FBbt:00000155 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:293011 is_a: UBERON:0000033 ! head intersection_of: UBERON:0000033 ! head @@ -234551,7 +234900,7 @@ synonym: "type II pneumocyte secretion" EXACT [] xref: EMAPA:36551 xref: FMA:62780 xref: MA:0002534 -xref: MESH:D011663 +xref: MESH:D011663 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: NCIT:C13273 xref: UMLS:C0034085 {source="ncithesaurus:Lung_Surfactant"} xref: Wikipedia:Pulmonary_surfactant @@ -234568,7 +234917,7 @@ name: hepatic diverticulum namespace: uberon def: "An out-pocket of thickened ventral foregut epithelium adjacent to the developing heart. Constitutes the first morphological sign of the embryonic liver. The anterior portion of the hepatic diverticulum gives rise to the liver and intrahepatic biliary tree, while the posterior portion forms the gall bladder and extrahepatic bile ducts." [http://www.stembook.org/node/512, MP:MP] subset: pheno_slim -synonym: "diverticulum hepaticum" RELATED LATIN [Wikipedia:Hepatic_diverticulum] +synonym: "diverticulum hepaticum" RELATED OMO:0003011 [Wikipedia:Hepatic_diverticulum] synonym: "liver diverticulum" EXACT [XAO:0000101] xref: AAO:0011057 xref: EHDAA2:0000740 @@ -234700,7 +235049,7 @@ namespace: uberon def: "The short narrow part of the stomach extending from the pyloric antrum to the pyloric sphincter." [MP:0010791, Wikipedia:Pyloric_canal] subset: pheno_slim synonym: "canalis pyloricus" EXACT [Wikipedia:Pyloric_canal] -synonym: "canalis pyloricus" RELATED LATIN [Wikipedia:Pyloric_canal] +synonym: "canalis pyloricus" RELATED OMO:0003011 [Wikipedia:Pyloric_canal] xref: EMAPA:37944 {source="MA:th"} xref: FMA:14580 xref: SCTID:245417002 @@ -234790,8 +235139,8 @@ namespace: uberon def: "The largest lung subunit in which all airways participate in gas exchange, and it is composed of the parenchyma of the respiratory bronchioles, alveolar ducts, and alveoli." [MP:0010911, PMID:2014492, PMID:3382030, Wikipedia:Acinus#The_Lungs] subset: human_reference_atlas subset: pheno_slim -synonym: "acinus pulmonaris" EXACT LATIN [FMA:7313, FMA:TA] -synonym: "arbor alveolaris" EXACT LATIN [FMA:7313, FMA:TA] +synonym: "acinus pulmonaris" EXACT OMO:0003011 [FMA:7313, FMA:TA] +synonym: "arbor alveolaris" EXACT OMO:0003011 [FMA:7313, FMA:TA] synonym: "pulmonary acini" EXACT OMO:0003004 [PMID:37025383] xref: EMAPA:37941 {source="MA:th"} xref: FMA:7313 @@ -234927,8 +235276,8 @@ namespace: uberon def: "The hemorrhoidal plexus (or rectal venous plexus) surrounds the rectum, and communicates in front with the vesical venous plexus in the male, and the uterovaginal plexus in the female. A free communication between the portal and systemic venous systems is established through the hemorrhoidal plexus." [Wikipedia:Rectal_venous_plexus] synonym: "haemorrhoidal plexus" RELATED [Wikipedia:Rectal_venous_plexus] synonym: "hemorrhoidal plexus" RELATED [Wikipedia:Rectal_venous_plexus] -synonym: "plexus haemorrhoidalis" RELATED LATIN [Wikipedia:Rectal_venous_plexus] -synonym: "plexus venosus rectalis" RELATED LATIN [Wikipedia:Rectal_venous_plexus] +synonym: "plexus haemorrhoidalis" RELATED OMO:0003011 [Wikipedia:Rectal_venous_plexus] +synonym: "plexus venosus rectalis" RELATED OMO:0003011 [Wikipedia:Rectal_venous_plexus] xref: FMA:18933 xref: NCIT:C32728 xref: SCTID:303051005 @@ -235016,7 +235365,7 @@ synonym: "lateral line organ" BROAD [ZFA:0000243] synonym: "neuromast organ" EXACT [PHENOSCAPE:wd] synonym: "neuromasts" EXACT OMO:0003004 [ZFA:0000243] xref: AAO:0001004 -xref: BTO:0006219 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: BTO:0006219 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: EFO:0003513 xref: TAO:0000243 xref: ZFA:0000243 @@ -235096,7 +235445,7 @@ property_value: UBPROP:0000001 "Replacement bone that forms within the connectiv id: UBERON:0008921 name: substratum of layer of retina namespace: uberon -def: "." [http://retina.anatomy.upenn.edu/~lance/eye/retina_gross.html, UBERON:CL_meeting_20110725] +def: "Missing definition for term UBERON:0008921. Please replace it using linked reference." [UBERON:CL_meeting_20110725] is_a: UBERON:0022303 ! nervous system cell part layer relationship: part_of UBERON:0000966 ! retina @@ -235300,6 +235649,7 @@ synonym: "tooth follicle" RELATED [BTO:0000337] xref: BTO:0000337 xref: EMAPA:35275 xref: MA:0003121 +xref: MESH:D003795 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} xref: NCIT:C34138 xref: SCTID:110975002 xref: Wikipedia:Dental_follicle @@ -235321,7 +235671,7 @@ synonym: "true apocrine gland" EXACT [] xref: BTO:0001162 xref: EMAPA:35141 xref: MA:0003040 -xref: MESH:D001050 +xref: MESH:D001050 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: SCTID:361698000 xref: Wikipedia:Apocrine is_a: UBERON:0002365 ! exocrine gland @@ -235423,7 +235773,7 @@ id: UBERON:0009027 name: vesical artery namespace: uberon def: "An artery that supplies blood to the urinary bladder." [http://orcid.org/0000-0002-6601-2165] -synonym: "arteria vesicali" EXACT LATIN [] +synonym: "arteria vesicali" EXACT OMO:0003011 [] synonym: "vesical arteries" EXACT OMO:0003004 [] xref: EMAPA:37131 {source="MA:th"} xref: MA:0002078 @@ -235439,8 +235789,8 @@ name: pudendal vein namespace: uberon def: "Either the internal or external pudendal vein, running from the genital-vulvar area and abdomen and down the leg." [http://orcid.org/0000-0002-6601-2165, https://veintreatmentcenter.com/vein-information/pudendal-veins/] synonym: "pudic vein" RELATED [] -synonym: "vena pudendae" EXACT LATIN [doi:10.1002/ca.23705] -synonym: "vena pudendales" EXACT LATIN [doi:10.1002/ca.23705] +synonym: "vena pudendae" EXACT OMO:0003011 [doi:10.1002/ca.23705] +synonym: "vena pudendales" EXACT OMO:0003011 [doi:10.1002/ca.23705] xref: EMAPA:37184 {source="MA:th"} xref: MA:0002202 xref: SCTID:395225000 @@ -235522,7 +235872,7 @@ name: prostatic venous plexus namespace: uberon def: "The prostatic veins form a well-marked prostatic plexus which lies partly in the fascial sheath of the prostate and partly between the sheath and the prostatic capsule. It communicates with the pudendal and vesical plexuses." [Wikipedia:Prostatic_venous_plexus] subset: human_reference_atlas -synonym: "plexus venosus prostaticus" RELATED LATIN [Wikipedia:Prostatic_venous_plexus] +synonym: "plexus venosus prostaticus" RELATED OMO:0003011 [Wikipedia:Prostatic_venous_plexus] synonym: "pudendal venous plexus" RELATED [FMA:29711] xref: FMA:29711 xref: SCTID:303052003 @@ -235605,6 +235955,7 @@ synonym: "pregnant adult stage" RELATED [BTO:0004733] synonym: "pregnant organism" RELATED [] synonym: "pregnant stage" RELATED [BTO:0004733] xref: BTO:0004733 +xref: IDOMAL:0000443 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} is_a: UBERON:0007023 ! adult organism intersection_of: UBERON:0007023 ! adult organism intersection_of: has_part UBERON:0000922 ! embryo @@ -235726,7 +236077,7 @@ namespace: uberon def: "Cranial ganglion which develops from an epibranchial placode." [PMID:20133851, ZFIN:curator] comment: Epibranchial ganglia orchestrate the development of the cranial neurogenic crest synonym: "epibranchial ganglia" EXACT OMO:0003004 [ZFA:0001555] -xref: BTO:0006250 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: BTO:0006250 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: TAO:0001555 xref: ZFA:0001555 is_a: UBERON:0001714 {source="ZFA"} ! cranial ganglion @@ -236077,12 +236428,12 @@ subset: pheno_slim synonym: "arm pit" EXACT [Wikipedia:Axilla] synonym: "armpit" EXACT [Wikipedia:Axilla] synonym: "armpits" RELATED [Wikipedia:Axilla] -synonym: "axilla" RELATED LATIN [Wikipedia:Axilla] +synonym: "axilla" RELATED OMO:0003011 [Wikipedia:Axilla] synonym: "axillae" RELATED [Wikipedia:Axilla] synonym: "axillary region" EXACT [FMA:24864] synonym: "axillary region" RELATED [Wikipedia:Axilla] synonym: "oxter" RELATED [Wikipedia:Axilla] -synonym: "regio axillaris" EXACT LATIN [FMA:TA] +synonym: "regio axillaris" EXACT OMO:0003011 [FMA:TA] synonym: "underarm" RELATED [Wikipedia:Axilla] xref: CALOHA:TS-2208 xref: EFO:0001395 @@ -237239,7 +237590,7 @@ name: set of lower jaw teeth namespace: uberon def: "A tooth row that is part of a skeleton of lower jaw." [OBOL:automatic] subset: pheno_slim -synonym: "arcus dentalis inferior" EXACT LATIN [FMA:TA] +synonym: "arcus dentalis inferior" EXACT OMO:0003011 [FMA:TA] synonym: "lower dental arcade" EXACT [FMA:55635] synonym: "lower jaw teeth" EXACT [EHDAA2:0001029] synonym: "mandibular dental arcade" RELATED [FMA:55635] @@ -237257,7 +237608,7 @@ name: set of upper jaw teeth namespace: uberon def: "A tooth row that is part of a skeleton of upper jaw." [OBOL:automatic] subset: pheno_slim -synonym: "arcus dentalis superior" EXACT LATIN [FMA:TA] +synonym: "arcus dentalis superior" EXACT OMO:0003011 [FMA:TA] synonym: "maxillary dental arcade" RELATED [FMA:55634] synonym: "set of all upper teeth" EXACT [FMA:55634] synonym: "upper dental arcade" EXACT [FMA:55634] @@ -237827,7 +238178,7 @@ namespace: uberon def: "Branch or outpocketing of the digestive tract." [https://orcid.org/0000-0002-6601-2165] synonym: "diverticulum of gut" RELATED [FBbt:00100316] synonym: "intestinal pouch" RELATED [] -xref: FBbt:00100316 +xref: FBbt:00100316 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0004921 ! subdivision of digestive tract is_a: UBERON:0009856 ! sac intersection_of: UBERON:0009856 ! sac @@ -238000,7 +238351,7 @@ synonym: "fore mesopodial skeleton" EXACT [] synonym: "fore mesopodium" RELATED [AAO:0000201] synonym: "fore mesopodium skeleton" EXACT [] synonym: "ossa carpi" EXACT [] -synonym: "ossa carpi" RELATED LATIN [Wikipedia:Carpus] +synonym: "ossa carpi" RELATED OMO:0003011 [Wikipedia:Carpus] synonym: "set of carpal bones" RELATED [FMA:71335] synonym: "skeletal parts of fore mesopodium" EXACT [] synonym: "skeleton of carpus" EXACT [] @@ -238045,7 +238396,7 @@ name: anal column namespace: uberon def: "One of a number of vertical folds, produced by an infolding of the mucous membrane and some of the muscular tissue in the upper half of the lumen of the anal canal[WP]." [Wikipedia:Anal_columns] synonym: "column of Morgagni" EXACT [FMA:15713] -synonym: "columnae anales" RELATED LATIN [Wikipedia:Anal_columns] +synonym: "columnae anales" RELATED OMO:0003011 [Wikipedia:Anal_columns] xref: FMA:15713 xref: NCIT:C32067 xref: SCTID:245444007 @@ -238086,7 +238437,7 @@ def: "An artery that supplies a renal lobe." [http://orcid.org/0000-0002-6601-21 subset: human_reference_atlas subset: pheno_slim synonym: "arteriae interlobares renis" EXACT OMO:0003004 [FMA:TA] -synonym: "arteriae interlobares renis" RELATED LATIN [Wikipedia:Interlobar_arteries] +synonym: "arteriae interlobares renis" RELATED OMO:0003011 [Wikipedia:Interlobar_arteries] synonym: "interlobar arteries of kidney" RELATED [FMA:71637] synonym: "interlobar artery of kidney" EXACT [FMA:71637] synonym: "kidney interlobar artery" EXACT [] @@ -238114,7 +238465,7 @@ synonym: "interlobar vein of kidney" EXACT [FMA:71631] synonym: "interlobar veins of kidney" RELATED [FMA:71631] synonym: "set of interlobar veins of kidney" RELATED [FMA:71631] synonym: "venae interlobares renis" EXACT OMO:0003004 [FMA:TA] -synonym: "venae interlobares renis" RELATED LATIN [Wikipedia:Interlobar_veins] +synonym: "venae interlobares renis" RELATED OMO:0003011 [Wikipedia:Interlobar_veins] xref: FMA:71631 xref: Wikipedia:Interlobar_veins is_a: UBERON:0001638 ! vein @@ -238182,7 +238533,7 @@ id: UBERON:0009911 name: lobule namespace: uberon subset: upper_level -synonym: "lobulus" EXACT LATIN [FMA:45737, FMA:TA] +synonym: "lobulus" EXACT OMO:0003011 [FMA:45737, FMA:TA] xref: FMA:45737 xref: NCIT:C12990 xref: UMLS:C0921005 {source="ncithesaurus:Lobule"} @@ -238195,7 +238546,7 @@ name: anatomical lobe namespace: uberon def: "A portion of an organ, such as the liver, lung, breast, or brain." [ncithesaurus:Lobe] subset: upper_level -synonym: "lobus" EXACT LATIN [FMA:45728, FMA:TA] +synonym: "lobus" EXACT OMO:0003011 [FMA:45728, FMA:TA] xref: FMA:45728 xref: NCIT:C13393 xref: UMLS:C0796494 @@ -238208,7 +238559,7 @@ namespace: uberon def: "The portion of a kidney consisting of a renal medullary pyramid and the renal cortex above it[MP]. It is composed of many renal lobules[WP]." [MP:0011381, Wikipedia:Renal_lobe] subset: pheno_slim synonym: "kidney lobe" EXACT [MP:0011381] -synonym: "lobi renales" RELATED LATIN [Wikipedia:Renal_lobe] +synonym: "lobi renales" RELATED OMO:0003011 [Wikipedia:Renal_lobe] synonym: "lobi renalis" EXACT OMO:0003004 [Wikipedia:Renal_lobe] synonym: "lobus renalis" EXACT [http://www.mondofacto.com/facts/dictionary?lobus+renalis] xref: FMA:17881 @@ -238234,7 +238585,7 @@ subset: pheno_slim synonym: "cortical lobule" RELATED [MP:0011382, Wikipedia:Cortical_lobule] synonym: "cortical lobule of kidney" RELATED [http://www.mondofacto.com/facts/dictionary?lobus+renalis] synonym: "kidney lobule" EXACT [MP:0011382] -synonym: "lobuli corticales renis" RELATED LATIN [Wikipedia:Cortical_lobule] +synonym: "lobuli corticales renis" RELATED OMO:0003011 [Wikipedia:Cortical_lobule] synonym: "lobulus corticalis renalis" RELATED [http://www.mondofacto.com/facts/dictionary?lobus+renalis] synonym: "lobulus renalis" EXACT [] synonym: "renal cortical lobule" RELATED [http://www.mondofacto.com/facts/dictionary?lobus+renalis] @@ -238365,7 +238716,7 @@ namespace: uberon def: "Cranial ectodermal placode with potential to develop into a component of the nervous system, such as nerves or ganglia." [http://orcid.org/0000-0002-6601-2165, PMID:11523831] subset: efo_slim synonym: "neurogenic placodes" EXACT OMO:0003004 [ZFA:0001309] -synonym: "placodae neurogenicae" RELATED LATIN [Wikipedia:Neurogenic_placodes] +synonym: "placodae neurogenicae" RELATED OMO:0003011 [Wikipedia:Neurogenic_placodes] xref: EFO:0003460 xref: TAO:0001309 xref: Wikipedia:Neurogenic_placodes @@ -238441,8 +238792,8 @@ id: UBERON:0009967 name: spleen venous sinus namespace: uberon subset: human_reference_atlas -synonym: "sinus lienalis" EXACT LATIN [FMA:TA] -synonym: "sinus splenicus" EXACT LATIN [FMA:TA] +synonym: "sinus lienalis" EXACT OMO:0003011 [FMA:TA] +synonym: "sinus splenicus" EXACT OMO:0003011 [FMA:TA] synonym: "splenic sinus" EXACT [FMA:62815] synonym: "venous sinus of red pulp of spleen" EXACT [FMA:62815] xref: EMAPA:37751 {source="MA:th"} @@ -238571,7 +238922,7 @@ subset: common_anatomy subset: upper_level synonym: "multicellular structure" EXACT [FBbt:00100313] xref: CARO:0010000 -xref: FBbt:00100313 +xref: FBbt:00100313 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0000061 ! anatomical structure intersection_of: UBERON:0000061 ! anatomical structure intersection_of: has_quality PATO:0001993 ! multicellular @@ -238589,7 +238940,7 @@ def: "A small cluster of cells of various types which form a discrete structure, comment: Examples include arthropod sensilla. subset: upper_level xref: CARO:0010001 -xref: FBbt:00007229 +xref: FBbt:00007229 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0000062 {source="CARO"} ! organ is_a: UBERON:0034922 {source="CARO"} ! cell cluster disjoint_from: UBERON:0011216 {source="FBbt"} ! organ system subdivision @@ -238779,7 +239130,7 @@ synonym: "apex of the tongue" RELATED [Wikipedia:Anterior_tongue] synonym: "buccal part of the tongue" RELATED [Wikipedia:Anterior_tongue] synonym: "front of the tongue" RELATED [Wikipedia:Anterior_tongue] synonym: "oral part of the tongue" RELATED [Wikipedia:Anterior_tongue] -synonym: "pars anterior dorsi linguae" RELATED LATIN [Wikipedia:Anterior_tongue] +synonym: "pars anterior dorsi linguae" RELATED OMO:0003011 [Wikipedia:Anterior_tongue] xref: EMAPA:37437 {source="MA:th"} xref: FMA:229084 xref: NCIT:C32130 @@ -238805,7 +239156,7 @@ synonym: "fundus gland" EXACT [] synonym: "gastric fundal gland" EXACT [] synonym: "gastric fundus gland" EXACT [] synonym: "gastric gland of fundus of stomach" EXACT [] -synonym: "glandulae gastricae" RELATED LATIN [Wikipedia:Fundic_glands] +synonym: "glandulae gastricae" RELATED OMO:0003011 [Wikipedia:Fundic_glands] xref: EMAPA:27161 xref: NCIT:C32643 xref: SCTID:268338004 @@ -239305,11 +239656,13 @@ id: UBERON:0010147 name: male accessory sex gland namespace: uberon def: "Any gland, other than the gonad, associated with the genital tract, such as the ampulla of the ductus deferens and the bulbourethral, prostate and vesicular glands of the male." [BTO:0004798] +subset: human_reference_atlas subset: pheno_slim synonym: "male accessory gland" RELATED [BTO:0004798] synonym: "male accessory reproductive gland" RELATED [] xref: BTO:0004798 is_a: UBERON:0005399 {source="BTO"} ! male reproductive gland +relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: UBERON:0010152 @@ -239332,7 +239685,7 @@ synonym: "frontosphenoid suture" EXACT [FMA:52938] synonym: "spheno-frontal suture" RELATED [] synonym: "sphenofrontal" RELATED [Wikipedia:Sphenofrontal_suture] synonym: "sphenofrontal suture of skull" EXACT [FMA:52938] -synonym: "sutura sphenofrontalis" RELATED LATIN [Wikipedia:Sphenofrontal_suture] +synonym: "sutura sphenofrontalis" RELATED OMO:0003011 [Wikipedia:Sphenofrontal_suture] xref: FMA:52938 xref: SCTID:136349005 xref: Wikipedia:Sphenofrontal_suture @@ -239396,7 +239749,7 @@ namespace: uberon def: "An anatomical cluster that composed_primarily_of a strand of hair." [OBOL:automatic] synonym: "hairs" EXACT [FMA:70752] synonym: "hairs set" EXACT [FMA:70752] -synonym: "pili" EXACT LATIN [FMA:TA] +synonym: "pili" EXACT OMO:0003011 [FMA:TA] synonym: "set of hairs" EXACT [FMA:70752] xref: FMA:70752 is_a: UBERON:0034925 ! anatomical collection @@ -239458,7 +239811,7 @@ def: "Any of the numerous small mucous-secreting glands located in the wall of t subset: pheno_slim synonym: "gland of Littre" EXACT [] synonym: "gland of male urethra" EXACT [] -synonym: "glandulae urethrales urethrae masculinae" RELATED LATIN [Wikipedia:Urethral_gland] +synonym: "glandulae urethrales urethrae masculinae" RELATED OMO:0003011 [Wikipedia:Urethral_gland] synonym: "Littre's gland" EXACT [FMA:21443] synonym: "male urethra gland" EXACT [] synonym: "urethral gland (male)" EXACT [FMA:21443] @@ -239515,6 +239868,21 @@ intersection_of: UBERON:0006675 ! venous valve intersection_of: part_of UBERON:0002078 ! right cardiac atrium property_value: UBPROP:0000012 "part_of in EHDAA2. Only child in MA." xsd:string {external_ontology="EHDAA2"} +[Term] +id: UBERON:0010190 +name: pair of dorsal aortae +namespace: uberon +def: "The paired arterial structures of the embryo that supplies each developing somite via efferent segmental arteries; the dorsal aortae articulate with the umbilical arteries, which return mixed blood to the villi of the chorion for reoxygenation." [ISBN:0-914294-08-3, MP:0004787] +subset: pheno_slim +synonym: "paired dorsal aortae" EXACT [EHDAA2:0000410] +xref: EHDAA2:0000410 +xref: EMAPA:18606 +xref: MA:0000476 +is_a: PR:000050567 ! protein-containing material entity +is_a: UBERON:0000481 {source="EHDAA2"} ! multi-tissue structure +relationship: has_part UBERON:0005805 ! dorsal aorta +relationship: part_of UBERON:0010191 {source="EHDAA2"} ! aortic system + [Term] id: UBERON:0010191 name: aortic system @@ -239894,7 +240262,7 @@ id: UBERON:0010272 name: hyoid apparatus namespace: uberon def: "A group of bones comprised of hyoid body and two pairs of cornua (i.e. greater cornua and lesser cornua), and lies just below the tongue, above the thyroid cartilage." [http://www.biology-online.org/dictionary/Hyoid_apparatus] -synonym: "apparatus hyobranchialis" RELATED LATIN [] +synonym: "apparatus hyobranchialis" RELATED OMO:0003011 [] synonym: "apparatus hyoideus" RELATED [http://www.biology-online.org/dictionary/Hyoid_apparatus] synonym: "hyobranchial apparatus" RELATED [AAO:0000225] synonym: "hyolingual system" RELATED [AAO:0000225] @@ -239944,7 +240312,7 @@ def: "A minute orifice on the summit of the papillae lacrimales, which is the co subset: pheno_slim synonym: "lacrimal point" RELATED [Wikipedia:Lacrimal_punctum] synonym: "lacrimal puncta" RELATED OMO:0003004 [Wikipedia:Lacrimal_punctum] -synonym: "puncta lacrimalia" RELATED LATIN [Wikipedia:Lacrimal_punctum] +synonym: "puncta lacrimalia" RELATED OMO:0003011 [Wikipedia:Lacrimal_punctum] xref: FMA:59365 xref: SCTID:263344003 xref: Wikipedia:Lacrimal_punctum @@ -239985,7 +240353,6 @@ property_value: editor_note "we follow ZFA in temporally dividing midbrain NT fr id: UBERON:0010291 name: layer of sclera namespace: uberon -def: "." [Wikipedia:Sclera#Histology] xref: Wikipedia:Sclera#Histology is_a: UBERON:0004923 ! organ component layer relationship: part_of UBERON:0001773 {source="cjm"} ! sclera @@ -240010,7 +240377,7 @@ synonym: "scleral stroma" EXACT [FMA:58365] synonym: "stroma of sclera" EXACT [FMA:58365] synonym: "subsantia propria" BROAD [] synonym: "subsantia propria sclerae" EXACT [FMA:58365] -synonym: "substantia propria sclerae" EXACT LATIN [FMA:58365, FMA:TA] +synonym: "substantia propria sclerae" EXACT OMO:0003011 [FMA:58365, FMA:TA] xref: FMA:58365 xref: NCIT:C33652 xref: SCTID:368851004 @@ -240041,7 +240408,7 @@ subset: efo_slim synonym: "amnion-serosa" RELATED [BTO:0004800] xref: BTO:0004800 xref: EFO:0000250 -xref: FBbt:00000095 +xref: FBbt:00000095 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0010303 {source="DOI:10.1073/pnas.0709145105"} ! extraembryonic epithelium relationship: only_in_taxon NCBITaxon:6656 {notes="Cyclorrhapha", source="DOI:10.1073/pnas.0709145105"} ! Arthropoda property_value: editor_note "May be obsoleted once added to insect ontology. Coordinate with cell type in CL" xsd:string @@ -240425,8 +240792,8 @@ namespace: uberon def: "The first step in ossification of the cartilage is that the cartilage cells, at the point where ossification is commencing and which is termed a ossification center, enlarge and arrange themselves in rows. The matrix in which they are imbedded increases in quantity, so that the cells become further separated from each other. A deposit of calcareous material now takes place in this matrix, between the rows of cells, so that they become separated from each other by longitudinal columns of calcified matrix, presenting a granular and opaque appearance. Here and there the matrix between two cells of the same row also becomes calcified, and transverse bars of calcified substance stretch across from one calcareous column to another. Thus there are longitudinal groups of the cartilage cells enclosed in oblong cavities, the walls of which are formed of calcified matrix which cuts off all nutrition from the cells; the cells, in consequence, atrophy, leaving spaces called the primary areolC&." [Wikipedia:Ossification_center] subset: pheno_slim synonym: "center of ossification" RELATED [Wikipedia:Ossification_center] -synonym: "centrum ossificationis" EXACT LATIN [FMA:TA] -synonym: "centrum ossificationis" RELATED LATIN [Wikipedia:Ossification_center] +synonym: "centrum ossificationis" EXACT OMO:0003011 [FMA:TA] +synonym: "centrum ossificationis" RELATED OMO:0003011 [Wikipedia:Ossification_center] synonym: "ossification centre" EXACT [FMA:75436] xref: FMA:75436 xref: Wikipedia:Ossification_center @@ -240567,7 +240934,7 @@ def: "A vasculature that is part of a conjunctiva." [OBOL:automatic] synonym: "conjunctival veins" EXACT [FMA:70887] synonym: "conjunctival veins set" EXACT [FMA:70887] synonym: "set of conjunctival veins" EXACT [FMA:70887] -synonym: "venae conjunctivales" EXACT LATIN [FMA:TA] +synonym: "venae conjunctivales" EXACT OMO:0003011 [FMA:TA] xref: FMA:70887 is_a: UBERON:0002203 ! vasculature of eye intersection_of: UBERON:0002049 ! vasculature @@ -240593,7 +240960,7 @@ id: UBERON:0010368 name: pulmonary lobule namespace: uberon def: "The smallest anatomical unit of the lung, measuring 0.50 to 2.00 cm in diameter. Each lobule is composed of 4-8 terminal bronchioles and their distal alveolar ducts and sacs. The lobules are separated by fibrous interlobular septa." [ncithesaurus:Pulmonary_Lobule] -synonym: "lobulus pulmonis" EXACT LATIN [FMA:75739, FMA:TA] +synonym: "lobulus pulmonis" EXACT OMO:0003011 [FMA:75739, FMA:TA] xref: FMA:75739 xref: NCIT:C33428 is_a: UBERON:0009911 ! lobule @@ -240607,7 +240974,7 @@ name: secondary pulmonary lobule namespace: uberon def: "A unit of lung supplied by three to five terminal bronchioles and contained by fibrous septa." [PMID:3259815] subset: human_reference_atlas -synonym: "lobulus pulmonis secondarius" EXACT LATIN [FMA:7414, FMA:TA] +synonym: "lobulus pulmonis secondarius" EXACT OMO:0003011 [FMA:7414, FMA:TA] synonym: "respiratory lobule" RELATED [PMID:18403324] xref: FMA:7414 is_a: UBERON:0010368 {source="FMA"} ! pulmonary lobule @@ -241093,8 +241460,8 @@ def: "The ciliary processes are formed by the inward folding of the various laye synonym: "ciliary process" RELATED [Wikipedia:Ciliary_processes] synonym: "ciliary processes" EXACT [FMA:76551] synonym: "ciliary processes set" EXACT [FMA:76551] -synonym: "processus ciliares" EXACT LATIN [FMA:TA] -synonym: "processus ciliares" RELATED LATIN [Wikipedia:Ciliary_processes] +synonym: "processus ciliares" EXACT OMO:0003011 [FMA:TA] +synonym: "processus ciliares" RELATED OMO:0003011 [Wikipedia:Ciliary_processes] synonym: "set of ciliary processes" EXACT [FMA:76551] xref: FMA:76551 xref: SCTID:280860001 @@ -241113,7 +241480,7 @@ name: flat bone namespace: uberon def: "A bone that is shaped as a broad flat plate and composed of two thin layers of compact tissue enclosing between them a variable quantity of cancellous tissue, which is the location of red bone marrow." [Wikipedia:Flat_bone] comment: Examples: cranium, the ilium, sternum, rib cage, the sacrum and the scapula; the occipital, parietal, frontal, nasal, lacrimal, vomer, scapula, os coxC&, sternum, and ribs -synonym: "os planum" RELATED LATIN [Wikipedia:Flat_bone] +synonym: "os planum" RELATED OMO:0003011 [Wikipedia:Flat_bone] xref: FMA:7476 xref: galen:FlatBone xref: NCIT:C32616 @@ -241214,7 +241581,6 @@ relationship: part_of UBERON:0008193 ! pneumatized bone id: UBERON:0010531 name: metanephros induced blastemal cells namespace: uberon -def: "." [http://www.embryology.ch/anglais/turinary/urinhaute03.html] synonym: "cap mesenchyme of metanephros of urinary system" RELATED [EMAPA:17645] synonym: "induced blastemal cells" EXACT [VHOG:0001241] synonym: "nephrogenic interstitium" RELATED [] @@ -241394,11 +241760,11 @@ synonym: "fore metapodial skeleton" RELATED [] synonym: "fore metapodium" RELATED [AAO:0000946, http://en.wiktionary.org/wiki/metapodial, MA:th] synonym: "metacarpal bones" EXACT [FMA:71336] synonym: "metacarpal skeleton" EXACT [] -synonym: "metacarpalia" RELATED LATIN [Wikipedia:Metacarpus] +synonym: "metacarpalia" RELATED OMO:0003011 [Wikipedia:Metacarpus] synonym: "metacarpals [I-V]" EXACT [FMA:71336] synonym: "metacarpals set" EXACT [FMA:71336] -synonym: "ossa metacarpalia [I-V]" EXACT LATIN [FMA:71336, FMA:TA] -synonym: "ossa metacarpi [I-V]" EXACT LATIN [FMA:71336, FMA:TA] +synonym: "ossa metacarpalia [I-V]" EXACT OMO:0003011 [FMA:71336, FMA:TA] +synonym: "ossa metacarpi [I-V]" EXACT OMO:0003011 [FMA:71336, FMA:TA] synonym: "set of metacarpal bones" EXACT [FMA:71336] synonym: "set of metacarpals" EXACT [FMA:71336] synonym: "set of metacarpals [I-V]" EXACT [FMA:71336] @@ -241430,9 +241796,9 @@ synonym: "metatarsal bones set" EXACT [FMA:71340] synonym: "metatarsal skeleton" EXACT [] synonym: "metatarsalia" RELATED [] synonym: "metatarsals [I-V]" EXACT [FMA:71340] -synonym: "ossa metatarsalia" RELATED LATIN [Wikipedia:Metatarsus] -synonym: "ossa metatarsalia [I-V]" EXACT LATIN [FMA:71340, FMA:TA] -synonym: "ossa metatarsi[I-V]" EXACT LATIN [FMA:71340, FMA:TA] +synonym: "ossa metatarsalia" RELATED OMO:0003011 [Wikipedia:Metatarsus] +synonym: "ossa metatarsalia [I-V]" EXACT OMO:0003011 [FMA:71340, FMA:TA] +synonym: "ossa metatarsi[I-V]" EXACT OMO:0003011 [FMA:71340, FMA:TA] synonym: "posterior metapodial skeleton" EXACT [] synonym: "posterior metapodium" RELATED [VSAO:0005027, VSAO:NI] synonym: "set of metatarsal bones" EXACT [FMA:71340] @@ -241880,7 +242246,7 @@ synonym: "hindlimb zygopod skeleton" EXACT [] synonym: "mesomere 2 of pelvic appendage" RELATED HOMOLOGY [ISBN:0226313409] synonym: "posterior zeugopodium" RELATED INCONSISTENT [VSAO:0005014] synonym: "posterior zeugopodium skeleton" EXACT [] -synonym: "skeleton cruris" EXACT LATIN [NominaAnatomicaVeterinaria:2005] +synonym: "skeleton cruris" EXACT OMO:0003011 [NominaAnatomicaVeterinaria:2005] xref: AAO:0000216 xref: VSAO:0005014 is_a: UBERON:0011584 ! zeugopodial skeleton @@ -242072,7 +242438,7 @@ def: "A major subdivision of an organism that divides an organism along an axis subset: upper_level synonym: "appendage segment" EXACT [FBbt:00007018] synonym: "appendicular segment" EXACT [] -xref: FBbt:00007018 +xref: FBbt:00007018 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0000475 ! organism subdivision relationship: part_of UBERON:0000026 ! appendage @@ -242543,7 +242909,7 @@ def: "A cartilage element that is part of a splanchnocranium." [OBOL:automatic] subset: efo_slim synonym: "pharyngeal arch cartilages" EXACT OMO:0003004 [ZFA:0001460] synonym: "splanchnocranium cartilage" EXACT [ZFA:0001460] -xref: BTO:0006051 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: BTO:0006051 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: EFO:0003689 xref: TAO:0001460 xref: ZFA:0001460 @@ -242698,7 +243064,7 @@ id: UBERON:0011096 name: lacrimal nerve namespace: uberon def: "The lacrimal nerve is the smallest of the three branches of the ophthalmic division of the trigeminal nerve." [Wikipedia:Lacrimal_nerve] -synonym: "nervus lacrimalis" EXACT LATIN [Wikipedia:Lacrimal_nerve] +synonym: "nervus lacrimalis" EXACT OMO:0003011 [Wikipedia:Lacrimal_nerve] xref: FMA:52628 xref: NCIT:C32908 xref: SCTID:280218007 @@ -242771,7 +243137,7 @@ name: tarsometatarsal joint namespace: uberon def: "The tarsometatarsal articulations are arthrodial joints in the pes." [Wikipedia:Tarsometatarsal_articulations] subset: pheno_slim -synonym: "articulationes tarsometatarsales" RELATED LATIN [Wikipedia:Tarsometatarsal_articulations] +synonym: "articulationes tarsometatarsales" RELATED OMO:0003011 [Wikipedia:Tarsometatarsal_articulations] synonym: "cuboideometatarsal" RELATED [Wikipedia:Tarsometatarsal_articulations] synonym: "Lisfranc joint" RELATED [Wikipedia:Tarsometatarsal_articulations] synonym: "tarso-metatarsal join" EXACT [] @@ -242794,12 +243160,12 @@ id: UBERON:0011119 name: carpometacarpal joint namespace: uberon def: "The carpometacarpal joints (CMC) are joints in the wrist that articulates the distal row of carpal bones and the proximal bases of the metacarpal bones." [Wikipedia:Carpometacarpal_joint] -synonym: "articulationes carpometacarpeæ" EXACT LATIN [Wikipedia:Carpometacarpal_joint] +synonym: "articulationes carpometacarpeæ" EXACT OMO:0003011 [Wikipedia:Carpometacarpal_joint] synonym: "carpometacarpal" BROAD [Wikipedia:Carpometacarpal_joint] synonym: "carpometacarpal articulation" RELATED [Wikipedia:Carpometacarpal_joint] synonym: "CMJ" BROAD [Wikipedia:Carpometacarpal_joint] xref: FMA:35287 -xref: MESH:D052737 +xref: MESH:D052737 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: NCIT:C32265 xref: SCTID:361842002 xref: UMLS:C0224620 {source="ncithesaurus:Carpometacarpal_Joint"} @@ -242852,6 +243218,7 @@ synonym: "intercarpal" RELATED [Wikipedia:Intercarpal_articulations] synonym: "intercarpal articulation" RELATED [Wikipedia:Intercarpal_articulations] synonym: "midcarpal articulation" RELATED [Wikipedia:Intercarpal_articulations] xref: FMA:35292 +xref: MESH:D050824 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} xref: NCIT:C32264 xref: SCTID:182176003 xref: UMLS:C1262468 {source="ncithesaurus:Carpal_Joint"} @@ -243022,8 +243389,8 @@ def: "Subdivision of skull that consists of the facial bones." [http://www.bartl subset: pheno_slim synonym: "facial bone" RELATED [MA:0000318] synonym: "facial skeleton" EXACT [FMA:53673] -synonym: "ossa facialia" RELATED LATIN [Wikipedia:Facial_skeleton] -synonym: "ossa faciei" RELATED LATIN [Wikipedia:Facial_skeleton] +synonym: "ossa facialia" RELATED OMO:0003011 [Wikipedia:Facial_skeleton] +synonym: "ossa faciei" RELATED OMO:0003011 [Wikipedia:Facial_skeleton] synonym: "viscerocranium" RELATED INCONSISTENT [MA:0000318] xref: EHDAA2:0002206 xref: EHDAA:8361 @@ -243194,7 +243561,7 @@ def: "A muscle layer that is part of a large intestine." [OBOL:automatic] synonym: "muscular coat of large intestine" EXACT [FMA:14971] synonym: "muscular layer of large intestine" EXACT [FMA:14971] synonym: "muscularis externa of large intestine" EXACT [FMA:14971] -synonym: "tunica muscularis intestini crassi" EXACT LATIN [FMA:TA] +synonym: "tunica muscularis intestini crassi" EXACT OMO:0003011 [FMA:TA] xref: FMA:14971 xref: NCIT:C32927 xref: UMLS:C0734205 {source="ncithesaurus:Large_Intestinal_Muscular_Coat"} @@ -243213,7 +243580,7 @@ synonym: "muscular layer of small intestine" EXACT [FMA:14932] synonym: "muscularis externa of small intestine" EXACT [FMA:14932] synonym: "small intestine muscularis propria" EXACT [FMA:14932] synonym: "tunica muscularis (intestinum tenue)" EXACT [FMA:14932] -synonym: "tunica muscularis intestini tenuis" EXACT LATIN [FMA:TA] +synonym: "tunica muscularis intestini tenuis" EXACT OMO:0003011 [FMA:TA] xref: FMA:14932 xref: NCIT:C33569 xref: SCTID:362145004 @@ -243278,8 +243645,9 @@ name: organ system subdivision namespace: uberon def: "A subdivision of an anatomical system." [http://orcid.org/0000-0002-6601-2165] subset: common_anatomy +subset: human_reference_atlas subset: upper_level -xref: FBbt:00007330 +xref: FBbt:00007330 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:67509 xref: SCTID:91690000 is_a: UBERON:0010000 {source="FBbt"} ! multicellular anatomical structure @@ -243287,6 +243655,7 @@ relationship: part_of UBERON:0000467 ! anatomical system relationship: present_in_taxon NCBITaxon:33090 ! Viridiplantae relationship: present_in_taxon NCBITaxon:33208 ! Metazoa relationship: present_in_taxon NCBITaxon:4751 ! Fungi +relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: UBERON:0011222 @@ -243417,7 +243786,7 @@ namespace: uberon def: "The submucous layer of the wall of the uterine tube." [BTO:0002116] synonym: "submucosa of fallopian tube" EXACT [] synonym: "submucous layer of uterine tube" RELATED [BTO:0002116] -synonym: "tela submucosa tubae uterinae" EXACT LATIN [BTO:0002116] +synonym: "tela submucosa tubae uterinae" EXACT OMO:0003011 [BTO:0002116] synonym: "uterine submucosa" RELATED [] xref: BTO:0002116 xref: SCTID:245489008 @@ -243992,9 +244361,8 @@ is_a: UBERON:0011693 ! extraembryonic portion of umbilical artery id: UBERON:0011757 name: differentiated genital tubercle namespace: uberon -def: "." [Wikipedia:Primordial_phallus] synonym: "phallus" RELATED [Wikipedia:Primordial_phallus] -synonym: "phallus primordialis" RELATED LATIN [Wikipedia:Primordial_phallus] +synonym: "phallus primordialis" RELATED OMO:0003011 [Wikipedia:Primordial_phallus] synonym: "primordial phallus" RELATED [Wikipedia:Primordial_phallus] xref: NCIT:C34274 xref: UMLS:C1514448 {source="ncithesaurus:Primordial_Phallus"} @@ -244227,8 +244595,8 @@ id: UBERON:0011825 name: loose connective tissue namespace: uberon def: "Irregular connective tissue, the intercellular matrix of which contains a sparse irregular network of collagen and elastic fiber bundles. Examples: areolar tissue, neuroglial tissue, mucoid tissue." [FMA:19783] -synonym: "textus connectivus collagenosus laxus" EXACT LATIN [FMA:19783, FMA:TA] -synonym: "textus connectivus laxus" EXACT LATIN [FMA:19783, FMA:TA] +synonym: "textus connectivus collagenosus laxus" EXACT OMO:0003011 [FMA:19783, FMA:TA] +synonym: "textus connectivus laxus" EXACT OMO:0003011 [FMA:19783, FMA:TA] xref: FMA:19783 xref: NCIT:C33007 xref: UMLS:C1253917 {source="ncithesaurus:Loose_Connective_Tissue"} @@ -244386,7 +244754,7 @@ id: UBERON:0011875 name: ligament of sternoclavicular joint namespace: uberon def: "A skeletal ligament that is part of a sternoclavicular joint." [OBOL:automatic] -synonym: "ligamentum sternoclavicularis" EXACT LATIN [] +synonym: "ligamentum sternoclavicularis" EXACT OMO:0003011 [] synonym: "sternoclavicular joint ligament" EXACT [FMA:63980] xref: FMA:63980 xref: SCTID:182386007 @@ -244403,9 +244771,9 @@ def: "A muscle layer that is part of a wall of esophagus." [OBOL:automatic] synonym: "muscle coat of esophagus" EXACT [FMA:62998] synonym: "muscular coat of oesophagus" EXACT [FMA:62998] synonym: "muscular layer of oesophagus" EXACT [FMA:62998] -synonym: "tela muscularis (oesophagus)" EXACT LATIN [FMA:62998, FMA:TA] -synonym: "tunica muscularis esophagi" EXACT LATIN [] -synonym: "tunica muscularis oesophageae" EXACT LATIN [FMA:TA] +synonym: "tela muscularis (oesophagus)" EXACT OMO:0003011 [FMA:62998, FMA:TA] +synonym: "tunica muscularis esophagi" EXACT OMO:0003011 [] +synonym: "tunica muscularis oesophageae" EXACT OMO:0003011 [FMA:TA] xref: FMA:62998 is_a: UBERON:0018261 ! muscular coat of digestive tract intersection_of: UBERON:0006660 ! muscular coat @@ -244601,10 +244969,8 @@ relationship: part_of UBERON:0006003 {source="ISBN:0123813611"} ! integumentary id: UBERON:0011945 name: luminal layer of epithelium namespace: uberon -subset: human_reference_atlas is_a: UBERON:0005162 ! multi cell part structure relationship: part_of UBERON:0000483 ! epithelium -relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: UBERON:0011947 @@ -244748,7 +245114,7 @@ def: "A skeletal ligament that connects a tibia and connects a tarsal skeleton." synonym: "deltoid collateral ligament of ankle joint" EXACT [FMA:44055] synonym: "deltoid ligament of ankle joint" EXACT [FMA:44055] synonym: "ligamentum collaterale mediale (articulatio talocruralis)" EXACT [FMA:44055] -synonym: "ligamentum collaterale mediale articulationis talocruralis" EXACT LATIN [FMA:44055, FMA:TA] +synonym: "ligamentum collaterale mediale articulationis talocruralis" EXACT OMO:0003011 [FMA:44055, FMA:TA] synonym: "ligamentum deltoideum" EXACT [FMA:TA] synonym: "ligamentum deltoideum (articulatio talocruralis)" EXACT [FMA:44055] synonym: "medial collateral ligament of ankle joint" EXACT [FMA:44055] @@ -245030,6 +245396,20 @@ intersection_of: luminal_space_of UBERON:0002184 ! segmental bronchus relationship: luminal_space_of UBERON:0002184 ! segmental bronchus relationship: part_of UBERON:0002184 ! segmental bronchus +[Term] +id: UBERON:0012125 +name: dermatological-muscosal system +namespace: uberon +def: "Anatomical system that consists of the integumental system plus all mucosae and submucosae." [https://github.com/obophenotype/uberon/issues/53] +synonym: "dermatological system" RELATED [OBI:MC] +is_a: PR:000050567 ! protein-containing material entity +is_a: UBERON:0000467 ! anatomical system +relationship: existence_ends_during UBERON:0000066 ! fully formed stage +relationship: has_part UBERON:0000009 ! submucosa +relationship: has_part UBERON:0000344 ! mucosa +relationship: has_part UBERON:0002072 ! hypodermis +relationship: has_part UBERON:0002097 ! skin of body + [Term] id: UBERON:0012139 name: segment of autopod @@ -245247,9 +245627,9 @@ synonym: "external meatus of urethra" EXACT [FMA:19650] synonym: "external urethral orifice" EXACT [FMA:19650] synonym: "external urethral ostium" EXACT [FMA:19650] synonym: "external urinary meatus" EXACT [FMA:19650] -synonym: "meatus urinarius" EXACT LATIN [] -synonym: "orificium urethrae externum" EXACT LATIN [] -synonym: "orificium urethræ externum" EXACT LATIN [] +synonym: "meatus urinarius" EXACT OMO:0003011 [] +synonym: "orificium urethrae externum" EXACT OMO:0003011 [] +synonym: "orificium urethræ externum" EXACT OMO:0003011 [] synonym: "urethral meatus" EXACT [FMA:19650] synonym: "urinary meatus" RELATED [] xref: EMAPA:37977 {source="MA:th"} @@ -245274,7 +245654,7 @@ synonym: "distal urethral opening of male" RELATED [EMAPA:36434] synonym: "external orifice of male urethra" EXACT [FMA:85265] synonym: "external urethral orifice (male)" EXACT [FMA:85265] synonym: "male urethra ostium" EXACT [MA:0002642] -synonym: "ostium urethrae externum (urethra masculina)" EXACT LATIN [FMA:TA] +synonym: "ostium urethrae externum (urethra masculina)" EXACT OMO:0003011 [FMA:TA] synonym: "urethral meatus of penile urethra" EXACT [EMAPA:36434] synonym: "urethral opening of penile urethra" RELATED [EMAPA:36434] xref: EMAPA:36434 @@ -245301,9 +245681,9 @@ synonym: "internal urethral orifice of urinary bladder" EXACT [FMA:85263] synonym: "internal urethral ostium" EXACT [FMA:85263] synonym: "internal urethral ostium" RELATED [MP:0011782] synonym: "internal urinary meatus" RELATED [MP:0011782] -synonym: "orificium urethrae internum" EXACT LATIN [MP:0011782] -synonym: "ostium orificium internum" EXACT LATIN [] -synonym: "ostium urethrae internum" EXACT LATIN [Wikipedia:Internal_urethral_orifice] +synonym: "orificium urethrae internum" EXACT OMO:0003011 [MP:0011782] +synonym: "ostium orificium internum" EXACT OMO:0003011 [] +synonym: "ostium urethrae internum" EXACT OMO:0003011 [Wikipedia:Internal_urethral_orifice] synonym: "vesicourethral orifice" EXACT [FMA:85263] xref: FMA:85263 xref: SCTID:362228001 @@ -245355,7 +245735,7 @@ subset: human_reference_atlas synonym: "ectocervix" EXACT [BTO:0001850, FMA:86484] synonym: "exocervix" RELATED [BTO:0001850] synonym: "portio vaginalis" EXACT [Wikipedia:Vaginal_portion_of_cervix] -synonym: "portio vaginalis cervicis" EXACT LATIN [BTO:0001850] +synonym: "portio vaginalis cervicis" EXACT OMO:0003011 [BTO:0001850] synonym: "uterine ectocervix" EXACT [CALOHA:TS-1098] synonym: "vaginal part of cervix" EXACT [FMA:77056] xref: BTO:0001850 @@ -245501,8 +245881,8 @@ name: gland of nasal mucosa namespace: uberon def: "The nasal glands are the seromucous glands in the respiratory region of the nasal mucous membrane. The three major types of nasal glands are anterior serous glands, seromucous glands, and Bowman glands." [Wikipedia:Nasal_glands] subset: pheno_slim -synonym: "glandula nasalis" EXACT LATIN [] -synonym: "glandulae nasales" EXACT LATIN [] +synonym: "glandula nasalis" EXACT OMO:0003011 [] +synonym: "glandulae nasales" EXACT OMO:0003011 [] synonym: "nasal gland" BROAD [] xref: EMAPA:37871 {source="MA:th"} xref: FMA:321518 @@ -245691,7 +246071,7 @@ id: UBERON:0012329 name: keratinized stratified squamous epithelium namespace: uberon def: "Keratinized stratified squamous epithelium is a stratified squamous epithelium, the cells of which synthesize and accumulate keratin." [FMA:45568, Wikipedia:Stratified_squamous_epithelium#Keratinized] -synonym: "epithelium stratificatum squamosum cornificatum" EXACT LATIN [FMA:45568] +synonym: "epithelium stratificatum squamosum cornificatum" EXACT OMO:0003011 [FMA:45568] xref: FMA:45568 xref: Wikipedia:Stratified_squamous_epithelium#Keratinized is_a: UBERON:0006915 ! stratified squamous epithelium @@ -245724,7 +246104,7 @@ def: "A broad fold of peritoneum that extends from the side of the uterus to the subset: human_reference_atlas synonym: "broad ligament" RELATED [MESH:A02.513.170] synonym: "broad uterine ligament" EXACT [FMA:16516] -synonym: "ligamentum latum uteri" RELATED LATIN [] +synonym: "ligamentum latum uteri" RELATED OMO:0003011 [] xref: FMA:16516 xref: MESH:D001956 xref: NCIT:C12318 @@ -246043,7 +246423,7 @@ synonym: "circular muscle layer of small intestine" EXACT [FMA:14935] synonym: "circular muscle of small intestine" EXACT [FMA:14935] synonym: "short pitch helicoidal muscle layer of small intestine" EXACT [FMA:14935] synonym: "stratum circulare (tunica muscularis)(intestinum tenue)" EXACT [FMA:14935] -synonym: "stratum circulare tunicae muscularis intestini tenuis" EXACT LATIN [FMA:14935, FMA:TA] +synonym: "stratum circulare tunicae muscularis intestini tenuis" EXACT OMO:0003011 [FMA:14935, FMA:TA] synonym: "stratum helicoidale brevis gradus tunicae muscularis intestini tenuis" EXACT [FMA:TA] xref: EMAPA:37562 {source="MA:th"} xref: FMA:14935 @@ -246067,7 +246447,7 @@ synonym: "longitudinal muscle layer of small intestine" EXACT [FMA:14936] synonym: "longitudinal muscle of small intestine" EXACT [FMA:14936] synonym: "stratum helicoidale longi gradus tunicae muscularis intestini tenuis" EXACT [FMA:TA] synonym: "stratum longitudinale (tunica muscularis) (intestinum tenue)" EXACT [FMA:14936] -synonym: "stratum longitudinale tunicae muscularis intestini tenuis" EXACT LATIN [FMA:14936, FMA:TA] +synonym: "stratum longitudinale tunicae muscularis intestini tenuis" EXACT OMO:0003011 [FMA:14936, FMA:TA] xref: EMAPA:37563 {source="MA:th"} xref: FMA:14936 xref: MA:0001561 @@ -246721,7 +247101,7 @@ def: "A vein that drains a lip." [OBOL:automatic] synonym: "labial vein" RELATED [] synonym: "labial vein of face" EXACT [] synonym: "lip vein" EXACT [OBOL:automatic] -synonym: "vena labialis" EXACT LATIN [] +synonym: "vena labialis" EXACT OMO:0003011 [] xref: SCTID:367664002 is_a: UBERON:0001638 ! vein intersection_of: UBERON:0001638 ! vein @@ -247029,7 +247409,7 @@ id: UBERON:0013241 name: embryonic urethral groove namespace: uberon def: "The precursor of the urethra." [http://orcid.org/0000-0002-6601-2165] -synonym: "sulcus urethralis primarius" EXACT LATIN [Wikipedia:Urethral_groove] +synonym: "sulcus urethralis primarius" EXACT OMO:0003011 [Wikipedia:Urethral_groove] synonym: "urethral groove" EXACT [] synonym: "urethral sulcus" EXACT [] xref: SCTID:361531004 @@ -247103,7 +247483,7 @@ id: UBERON:0013411 name: cranial cavity namespace: uberon def: "Anatomical cavity that is the lumen of the skull and contains the brain." [UBERON:cjm] -synonym: "cavitas cranii" EXACT LATIN [FMA:9644, FMA:TA] +synonym: "cavitas cranii" EXACT OMO:0003011 [FMA:9644, FMA:TA] synonym: "intracranial cavity" RELATED [Wikipedia:Cranial_cavity] synonym: "intracranial space" RELATED [Wikipedia:Cranial_cavity] xref: EMAPA:37497 {source="MA:th"} @@ -247441,7 +247821,7 @@ comment: Rods; necessary for the perception of movement, depth, and small differ synonym: "lateral geniculate nucleus magnocellular layer" EXACT [] synonym: "magnocellular layer of lateral geniculate nucleus" EXACT [] synonym: "strata magnocellularia" BROAD [] -synonym: "strata magnocellularia nuclei dorsalis corporis geniculati lateralis" EXACT LATIN [FMA:76989, FMA:TA] +synonym: "strata magnocellularia nuclei dorsalis corporis geniculati lateralis" EXACT OMO:0003011 [FMA:76989, FMA:TA] xref: DHBA:10431 xref: FMA:76989 xref: PBA:128013078 @@ -247458,7 +247838,7 @@ namespace: uberon comment: Cones; long- and medium-wavelength ("red" and "green" cones); necessary for the perception of color and form (fine details).[WP] synonym: "parvocellular layer of lateral geniculate nucleus" EXACT [] synonym: "strata parvocellularia" BROAD [] -synonym: "strata parvocellularia nuclei dorsalis corporis geniculati lateralis" EXACT LATIN [FMA:76992, FMA:TA] +synonym: "strata parvocellularia nuclei dorsalis corporis geniculati lateralis" EXACT OMO:0003011 [FMA:76992, FMA:TA] xref: FMA:76992 xref: PBA:128013091 is_a: UBERON:0013605 ! layer of lateral geniculate body @@ -247473,7 +247853,7 @@ name: koniocellular layer of dorsal nucleus of lateral geniculate body namespace: uberon comment: Short-wavelength "blue" cones.[WP] synonym: "konioocellular layer of lateral geniculate nucleus" EXACT [] -synonym: "stratum koniocellulare nuclei dorsalis corporis geniculati lateralis" EXACT LATIN [FMA:76988, FMA:TA] +synonym: "stratum koniocellulare nuclei dorsalis corporis geniculati lateralis" EXACT OMO:0003011 [FMA:76988, FMA:TA] xref: FMA:76988 is_a: UBERON:0013605 ! layer of lateral geniculate body relationship: part_of UBERON:0002479 ! dorsal lateral geniculate nucleus @@ -247615,7 +247995,7 @@ id: UBERON:0013687 name: pericranium namespace: uberon def: "Periosteum that is part of a skull." [OBOL:automatic] -synonym: "periosteum externum cranii" EXACT LATIN [FMA:76623, FMA:TA] +synonym: "periosteum externum cranii" EXACT OMO:0003011 [FMA:76623, FMA:TA] xref: FMA:76623 is_a: UBERON:0002515 ! periosteum intersection_of: UBERON:0002515 ! periosteum @@ -247756,7 +248136,6 @@ id: UBERON:0013702 name: body proper namespace: uberon def: "The region of the organism associated with the visceral organs." [AEO:0000103] -subset: human_reference_atlas subset: non_informative synonym: "body" RELATED [AEO:0000103] synonym: "whole body" RELATED [BTO:0001489] @@ -247766,7 +248145,6 @@ xref: EMAPA:36031 xref: FMA:231424 is_a: UBERON:0000475 {source="AEO"} ! organism subdivision relationship: part_of UBERON:0013701 ! main body axis -relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens property_value: UBPROP:0000001 "Cardinal body part, which consists of a maximal set of diverse subclasses of organ and organ part spatially associated with the vertebral column and ribcage. Examples: There is only one body proper[FMA:231424]." xsd:string {source="FMA:231424"} [Term] @@ -247877,7 +248255,7 @@ subset: pheno_slim synonym: "arterial blood" EXACT [FMA:83066] synonym: "blood in artery" EXACT [FMA:83066] synonym: "portion of arterial blood" EXACT [FMA:83066] -xref: BTO:0006188 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: BTO:0006188 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: FMA:83066 is_a: UBERON:0000178 ! blood intersection_of: UBERON:0000178 ! blood @@ -247892,7 +248270,7 @@ def: "A blood that is part of a vein." [OBOL:automatic] synonym: "blood in vein" EXACT [FMA:83067] synonym: "portion of venous blood" EXACT [FMA:83067] synonym: "venous blood" EXACT [FMA:83067] -xref: BTO:0006187 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: BTO:0006187 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: FMA:83067 is_a: UBERON:0000178 ! blood intersection_of: UBERON:0000178 ! blood @@ -248259,7 +248637,7 @@ name: respiratory muscle namespace: uberon def: "Muscle that is part of the respiratory system." [http://orcid.org/0000-0002-6601-2165] subset: pheno_slim -xref: MESH:D012132 +xref: MESH:D012132 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} is_a: UBERON:0003831 ! respiratory system muscle intersection_of: UBERON:0001630 ! muscle organ intersection_of: capable_of_part_of GO:0007585 ! respiratory gaseous exchange by respiratory system @@ -248547,12 +248925,12 @@ id: UBERON:0014540 name: white matter lamina of cerebellum namespace: uberon def: "The white laminae of cerebellum is subdivision of the cerebellar cortex comprised of myelinated axons lying deep to the granule cell layer of the cerebellar cortex." [http://neurolex.org/wiki/Category\:White_laminae_of_cerebellum] -synonym: "isthmus cinguli" RELATED LATIN [NeuroNames:163] -synonym: "isthmus gyri cingulatus" RELATED LATIN [NeuroNames:163] -synonym: "isthmus gyri cinguli" RELATED LATIN [NeuroNames:163] -synonym: "isthmus of gyrus fornicatus" RELATED LATIN [NeuroNames:163] +synonym: "isthmus cinguli" RELATED OMO:0003011 [NeuroNames:163] +synonym: "isthmus gyri cingulatus" RELATED OMO:0003011 [NeuroNames:163] +synonym: "isthmus gyri cinguli" RELATED OMO:0003011 [NeuroNames:163] +synonym: "isthmus of gyrus fornicatus" RELATED OMO:0003011 [NeuroNames:163] synonym: "isthmus of the cingulate gyrus" RELATED [NeuroNames:163] -synonym: "isthmus-2" RELATED LATIN [NeuroNames:163] +synonym: "isthmus-2" RELATED OMO:0003011 [NeuroNames:163] synonym: "lamina alba of cerebellar cortex" EXACT [] synonym: "laminae albae of cerebellar cortex" EXACT [] synonym: "laminae albae of cerebellar cortex" RELATED OMO:0003004 [BIRNLEX:1105] @@ -248683,8 +249061,8 @@ synonym: "cranial part of the accessory nerve" RELATED [NeuroNames:703] synonym: "cranial portion of eleventh cranial nerve" RELATED [NeuroNames:703] synonym: "internal branch of accessory nerve" RELATED [NeuroNames:703] synonym: "nerve XI (cranialis)" RELATED [NeuroNames:703] -synonym: "pars vagalis of nervus accessorius" RELATED LATIN [NeuroNames:703] -synonym: "radices craniales nervi accessorii" RELATED LATIN [NeuroNames:703] +synonym: "pars vagalis of nervus accessorius" RELATED OMO:0003011 [NeuroNames:703] +synonym: "radices craniales nervi accessorii" RELATED OMO:0003011 [NeuroNames:703] synonym: "root of accessory nerve" EXACT [] xref: BAMS:c11n xref: BIRNLEX:1580 @@ -248724,6 +249102,7 @@ subset: human_reference_atlas synonym: "cervical spinal cord anterior horn" RELATED [BIRNLEX:1680] synonym: "cervical spinal cord ventral horn" EXACT HUMAN_PREFERRED [BIRNLEX:1680] xref: BIRNLEX:1680 +xref: MESH:D066151 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} xref: SCTID:174363005 xref: UMLS:C0228615 {source="BIRNLEX:1680"} xref: UMLS:C1278740 {source="BIRNLEX:1680"} @@ -249021,13 +249400,70 @@ intersection_of: part_of UBERON:0002384 ! connective tissue relationship: connects UBERON:0009912 ! anatomical lobe relationship: part_of UBERON:0002384 ! connective tissue +[Term] +id: UBERON:0014765 +name: crus of diaphragm +namespace: uberon +def: "The domain of the diaphragm that is located dorsally and attaches to the vertebrae and surrounds the esophagus and aorta." [PMID:23586979] +comment: Classification notes: May be considered an external sphincter[PMID:8224664] +synonym: "crura of the diaphragm" RELATED [Wikipedia:Crus_of_diaphragm] +synonym: "crural diaphragm" EXACT [PMID:23586979] +synonym: "crus of the diaphragm" RELATED [Wikipedia:Crus_of_diaphragm] +synonym: "diaphragm crura" RELATED OMO:0003004 [] +synonym: "diaphragmatic crura" RELATED [Wikipedia:Crus_of_diaphragm] +xref: EHDAA2:0000597 +xref: EMAPA:17703 +xref: SCTID:244668003 +xref: VHOG:0001546 +xref: Wikipedia:Crus_of_diaphragm +is_a: UBERON:0000063 ! organ subunit +relationship: attaches_to UBERON:0001130 ! vertebral column +relationship: attaches_to UBERON:0006670 ! central tendon of diaphragm +relationship: intersects_midsagittal_plane_of UBERON:0001103 {source="PMID:23586979"} ! diaphragm +relationship: part_of UBERON:0001103 {source="PMID:23586979"} ! diaphragm + +[Term] +id: UBERON:0014766 +name: right crus of diaphragm +namespace: uberon +def: "A crus of diaphragm that is in_the_right_side_of a diaphragm." [OBOL:automatic] +synonym: "crus dextrum (Diaphragma)" EXACT OMO:0003011 [FMA:58286, FMA:TA] +synonym: "crus dextrum diaphragmatis" EXACT OMO:0003011 [FMA:58286, FMA:TA] +synonym: "external sphincter of esophagus" EXACT [FMA:58286] +synonym: "right crus of diaphragm" EXACT [FMA:58286] +synonym: "right crus of lumbar part of diaphragm" EXACT [FMA:58286] +xref: FMA:58286 +xref: SCTID:362690009 +is_a: UBERON:0014765 ! crus of diaphragm +intersection_of: UBERON:0014765 ! crus of diaphragm +intersection_of: in_right_side_of UBERON:0001103 ! diaphragm +relationship: in_right_side_of UBERON:0001103 ! diaphragm +property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI + +[Term] +id: UBERON:0014767 +name: left crus of diaphragm +namespace: uberon +def: "A crus of diaphragm that is in_the_left_side_of a diaphragm." [OBOL:automatic] +synonym: "crus sinistrum (Diaphragma)" EXACT OMO:0003011 [FMA:58287, FMA:TA] +synonym: "crus sinistrum diaphragmatis" EXACT OMO:0003011 [FMA:58287, FMA:TA] +synonym: "left crus of diaphragm" EXACT [FMA:58287] +synonym: "left crus of lumbar part of diaphragm" EXACT [FMA:58287] +xref: FMA:58287 +xref: SCTID:244937004 +is_a: UBERON:0014765 ! crus of diaphragm +intersection_of: UBERON:0014765 ! crus of diaphragm +intersection_of: in_left_side_of UBERON:0001103 ! diaphragm +relationship: in_left_side_of UBERON:0001103 ! diaphragm +property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI + [Term] id: UBERON:0014769 name: palpebral vein namespace: uberon def: "A blood vessel that drains from from an eyelid." [http://orcid.org/0000-0002-6601-2165] synonym: "palpebral veins" RELATED OMO:0003004 [] -synonym: "venae palpebrales" RELATED LATIN [] +synonym: "venae palpebrales" RELATED OMO:0003011 [] xref: FMA:51997 xref: SCTID:152208004 is_a: UBERON:0003496 ! head blood vessel @@ -249221,6 +249657,7 @@ id: UBERON:0014892 name: skeletal muscle organ, vertebrate namespace: uberon def: "A muscle organ that consists of skeletal muscle tissue ensheathed in epimysium, that develops from myotome and that is innervated by some somatic motor neuron. Skeletal muscles are typically attached (via a tendon) to a bone but there are exceptions (e.g. intrinsic tongue muscles)." [GOC:dos] +subset: human_reference_atlas synonym: "skeletal muscle" BROAD [] xref: AAO:0011099 xref: BTO:0001103 @@ -249251,6 +249688,7 @@ relationship: composed_primarily_of UBERON:0001134 ! skeletal muscle tissue relationship: develops_from UBERON:0003082 ! myotome relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of UBERON:0018254 ! skeletal musculature +relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: surrounded_by UBERON:0011899 ! epimysium relationship: synapsed_by CL:0000100 ! motor neuron @@ -249991,9 +250429,9 @@ namespace: uberon def: "The slightly constricted part of a tooth, between the crown and the root." [http://www.medilexicon.com/medicaldictionary.php?s=neck+of+tooth] synonym: "cervical margin of tooth" RELATED [http://www.medilexicon.com/medicaldictionary.php?s=neck+of+tooth] synonym: "cervical zone of tooth" RELATED [http://www.medilexicon.com/medicaldictionary.php?s=neck+of+tooth] -synonym: "cervix dentis" EXACT LATIN [FMA:TA] +synonym: "cervix dentis" EXACT OMO:0003011 [FMA:TA] synonym: "cervix of tooth" EXACT [FMA:55627] -synonym: "collumn dentis" EXACT LATIN [ncithesaurus:Collum_Dentis] +synonym: "collumn dentis" EXACT OMO:0003011 [ncithesaurus:Collum_Dentis] synonym: "dental neck" EXACT [http://www.medilexicon.com/medicaldictionary.php?s=neck+of+tooth] synonym: "tooth neck" EXACT [FMA:55627] xref: FMA:55627 @@ -250010,7 +250448,7 @@ name: non-connected functional system namespace: uberon def: "An anatomical group whose component structures share a common function." [AEO:0000093, AEO:JB, FBbt:00007278, FBC:DOS] xref: AEO:0000093 -xref: FBbt:00007278 +xref: FBbt:00007278 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0034923 ! disconnected anatomical group [Term] @@ -250247,7 +250685,7 @@ def: "A hepatic artery that is part of a left lobe of liver." [OBOL:automatic] subset: human_reference_atlas synonym: "left branch of hepatic artery" EXACT [FMA:14779] synonym: "left part of hepatic artery proper" EXACT [FMA:14779] -synonym: "ramus sinister (arteria hepatica propria)" EXACT LATIN [FMA:14779, FMA:TA] +synonym: "ramus sinister (arteria hepatica propria)" EXACT OMO:0003011 [FMA:14779, FMA:TA] xref: EMAPA:37096 {source="MA:th"} xref: FMA:14779 xref: MA:0003096 @@ -250265,7 +250703,7 @@ name: right hepatic artery namespace: uberon def: "A hepatic artery that is part of a right lobe of liver." [OBOL:automatic] subset: human_reference_atlas -synonym: "ramus dexter (arteria hepatica propria)" EXACT LATIN [FMA:14778, FMA:TA] +synonym: "ramus dexter (arteria hepatica propria)" EXACT OMO:0003011 [FMA:14778, FMA:TA] synonym: "right branch of hepatic artery proper" EXACT [FMA:14778] synonym: "right part of hepatic artery proper" EXACT [FMA:14778] xref: EMAPA:37376 {source="MA:th"} @@ -250367,7 +250805,7 @@ name: smooth muscle layer in fatty layer of subcutaneous tissue namespace: uberon def: "A smooth muscle tissue that is part of a hypodermis." [OBOL:automatic] synonym: "muscle layer in fatty layer of subcutaneous tissue" EXACT [FMA:77862] -synonym: "stratum musculosum panniculi adiposi telae subcutaneae" EXACT LATIN [FMA:77862, FMA:TA] +synonym: "stratum musculosum panniculi adiposi telae subcutaneae" EXACT OMO:0003011 [FMA:77862, FMA:TA] xref: FMA:77862 is_a: UBERON:0001135 ! smooth muscle tissue intersection_of: UBERON:0001135 ! smooth muscle tissue @@ -250379,7 +250817,7 @@ id: UBERON:0015786 name: respiratory segment of nasal mucosa namespace: uberon def: "The portion of the nasal mucosa that is part of the respiratory system." [http://orcid.org/0000-0002-6601-2165] -synonym: "pars respiratoria tunicae mucosae nasi" EXACT LATIN [FMA:77198, FMA:TA] +synonym: "pars respiratoria tunicae mucosae nasi" EXACT OMO:0003011 [FMA:77198, FMA:TA] synonym: "respiratory zone of nasal mucosa" EXACT [FMA:77198] xref: FMA:77198 is_a: UBERON:0001826 ! nasal cavity mucosa @@ -250726,6 +251164,7 @@ def: "Subdivision of thorax which includes all structures from the skin to the c subset: pheno_slim xref: EMAPA:37233 {source="MA:th"} xref: FMA:50060 +xref: MESH:D035441 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} xref: NCIT:C62484 xref: SCTID:181608004 is_a: UBERON:0000060 ! anatomical wall @@ -250797,14 +251236,14 @@ id: UBERON:0016479 name: capsule of liver namespace: uberon def: "A collagenous capsule covering the external surface of the liver." [Wikipedia:Fibrous_capsule_of_Glisson] -synonym: "capsula fibrosa perivascularis" EXACT LATIN [Wikipedia:Fibrous_capsule_of_Glisson] +synonym: "capsula fibrosa perivascularis" EXACT OMO:0003011 [Wikipedia:Fibrous_capsule_of_Glisson] synonym: "fibrous capsule of Glisson" RELATED [Wikipedia:Fibrous_capsule_of_Glisson] synonym: "fibrous capsule of liver" EXACT [FMA:15813] synonym: "glisson's capsule" EXACT [FMA:15813] synonym: "hepatic capsule" EXACT [FMA:15813] synonym: "liver capsule" RELATED [Wikipedia:Fibrous_capsule_of_Glisson] synonym: "tunica fibrosa (hepar)" EXACT [FMA:TA] -synonym: "tunica fibrosa hepatis" EXACT LATIN [FMA:15813, FMA:TA] +synonym: "tunica fibrosa hepatis" EXACT OMO:0003011 [FMA:15813, FMA:TA] xref: FMA:15813 xref: SCTID:362185005 xref: Wikipedia:Fibrous_capsule_of_Glisson @@ -251041,9 +251480,9 @@ subset: efo_slim subset: human_reference_atlas synonym: "frontal cortex" NARROW [FMA:61824] synonym: "frontal region" BROAD [FMA:61824] -synonym: "lobi frontales" EXACT LATIN [NeuroNames:56] -synonym: "lobus frontalis" EXACT LATIN [Wikipedia:Frontal_lobe] -synonym: "regio frontalis" BROAD LATIN [FMA:61824, FMA:TA] +synonym: "lobi frontales" EXACT OMO:0003011 [NeuroNames:56] +synonym: "lobus frontalis" EXACT OMO:0003011 [Wikipedia:Frontal_lobe] +synonym: "regio frontalis" BROAD OMO:0003011 [FMA:61824, FMA:TA] xref: BAMS:Frontal_lobe xref: BIRNLEX:928 xref: BM:Tel-Cx-FR @@ -251080,7 +251519,7 @@ synonym: "cerebral lobe" EXACT [BTO:0000445] synonym: "lobe of cerebral cortex" EXACT [BIRNLEX:922] synonym: "lobe parts of cerebral cortex" EXACT [BIRNLEX:922] synonym: "lobes of the brain" RELATED [BIRNLEX:922] -synonym: "lobi cerebri" EXACT LATIN [FMA:77800, FMA:TA] +synonym: "lobi cerebri" EXACT OMO:0003011 [FMA:77800, FMA:TA] synonym: "regional organ part of cerebral cortex" RELATED [FMA:68603] synonym: "segment of cerebral cortex" RELATED [BIRNLEX:922] xref: BIRNLEX:922 @@ -251148,6 +251587,7 @@ xref: DMBA:16016 xref: EMAPA:35667 xref: FMA:242203 xref: MA:0000916 +xref: MESH:D010296 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} xref: neuronames:2473 xref: NLX:79282 xref: SCTID:369217001 @@ -251205,6 +251645,7 @@ xref: DHBA:10235 xref: DMBA:16044 xref: FMA:242201 xref: MA:0000941 +xref: MESH:D013702 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} xref: NLX:94939 xref: SCTID:362343001 is_a: UBERON:0016529 ! cortex of cerebral lobe @@ -251422,7 +251863,7 @@ name: shoulder joint namespace: uberon def: "The joint that is formed by the union of the humerus, the scapula (or shoulder blade), and the clavicle (or collarbone). Commonly thought of as a single joint, the shoulder is actually made up of two separate joints - the glenohumeral and acromioclavicular joints." [http://www.innerbody.com/image/skel17.html] synonym: "joint of shoulder region" EXACT [] -xref: MESH:D012785 +xref: MESH:D012785 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: SCTID:361835002 is_a: UBERON:0000982 ! skeletal joint intersection_of: UBERON:0000982 ! skeletal joint @@ -251804,7 +252245,7 @@ name: cervical rib namespace: uberon def: "A rib that is attached to a cervical vertebra." [http://orcid.org/0000-0002-6601-2165] xref: EMAPA:37825 {source="MA:th"} -xref: MESH:D057070 +xref: MESH:D057070 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} is_a: UBERON:0002228 ! rib is_a: UBERON:0003458 ! neck bone intersection_of: UBERON:0002228 ! rib @@ -251999,7 +252440,7 @@ namespace: uberon def: "Accompanying vein of internal pudendal artery." [Wikipedia:Internal_pudendal_veins] subset: human_reference_atlas synonym: "internal pudic vein" RELATED [Wikipedia:Internal_pudendal_veins] -synonym: "vena pudenda interna" EXACT LATIN [Wikipedia:Internal_pudendal_veins] +synonym: "vena pudenda interna" EXACT OMO:0003011 [Wikipedia:Internal_pudendal_veins] xref: FMA:18917 xref: SCTID:14885008 xref: Wikipedia:Internal_pudendal_veins @@ -252015,12 +252456,14 @@ id: UBERON:0018254 name: skeletal musculature namespace: uberon subset: grouping_class +subset: human_reference_atlas xref: EHDAA2:0001842 xref: EMAPA:35578 xref: MA:0000165 is_a: UBERON:0000061 ! anatomical structure relationship: composed_primarily_of UBERON:0014892 ! skeletal muscle organ, vertebrate relationship: part_of UBERON:0000383 {source="MA"} ! musculature of body +relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens property_value: editor_note "Added for consistency with MA EMAPA and EHDAA2. See https://github.com/obophenotype/mouse-anatomy-ontology/issues/104" xsd:string [Term] @@ -252138,7 +252581,7 @@ id: UBERON:0018413 name: facial nerve canal namespace: uberon def: "A Z-shaped canal running through the temporal bone from the internal acoustic meatus to the stylomastoid foramen. It is located within the middle ear region, according to its shape it is divided into three main segments: the labyrinthine, the tympanic, and the mastoidal segment ." [Wikipedia:Facial_canal] -synonym: "canalis nervi facialis" EXACT LATIN [FMA:54952, FMA:TA] +synonym: "canalis nervi facialis" EXACT OMO:0003011 [FMA:54952, FMA:TA] synonym: "facial canal" EXACT [FMA:54952] synonym: "fallopian canal" RELATED [FMA:54952] xref: FMA:54952 @@ -252158,7 +252601,7 @@ comment: Taxon nodes: In humans, refers to anterior or posterior ethmoid foramin synonym: "ethmoid foramina" RELATED OMO:0003004 [] synonym: "ethmoidal foramen" EXACT [] synonym: "ethmoidal foramina" RELATED OMO:0003004 [] -synonym: "foramina ethmoidalia" EXACT LATIN [] +synonym: "foramina ethmoidalia" EXACT OMO:0003011 [] xref: Wikipedia:Ethmoidal_foramina is_a: UBERON:0013685 ! foramen of skull intersection_of: UBERON:0004111 ! anatomical conduit @@ -252628,8 +253071,8 @@ def: "The spinal accessory nucleus lies within the cervical spinal cord (C1-C5) comment: See also: Wikipedia:Spinal_accessory_nucleus synonym: "accessory neural nucleus" EXACT [FMA:83965] synonym: "accessory nucleus of anterior column of spinal cord" RELATED [NeuroNames:2003] -synonym: "nucleus accessorius columnae anterioris medullae spinalis" RELATED LATIN [NeuroNames:2003] -synonym: "nucleus nervi accessorii" RELATED LATIN [NeuroNames:2003] +synonym: "nucleus accessorius columnae anterioris medullae spinalis" RELATED OMO:0003011 [NeuroNames:2003] +synonym: "nucleus nervi accessorii" RELATED OMO:0003011 [NeuroNames:2003] synonym: "nucleus of accessory nerve" RELATED [NeuroNames:2003] synonym: "nucleus of the accessory nerve" RELATED [NeuroNames:2003] synonym: "nucleus of the spinal accessory nerve" RELATED [NeuroNames:2003] @@ -253530,7 +253973,7 @@ namespace: uberon def: "Material anatomical entity consisting of multiple anatomical structures that are not connected to each other." [CARO:0020000] subset: common_anatomy xref: CARO:0020000 -xref: FBbt:00007276 +xref: FBbt:00007276 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0000465 {source="CARO"} ! material anatomical entity relationship: composed_primarily_of UBERON:0000061 ! anatomical structure relationship: has_component UBERON:0000061 {minCardinality="2"} ! anatomical structure @@ -253558,7 +254001,7 @@ name: anatomical row namespace: uberon def: "An anatomical collection that is arranged in a line." [http://orcid.org/0000-0002-6601-2165] subset: common_anatomy -xref: FBbt:00100152 +xref: FBbt:00100152 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0034925 ! anatomical collection relationship: present_in_taxon NCBITaxon:33090 ! Viridiplantae relationship: present_in_taxon NCBITaxon:33208 ! Metazoa @@ -253656,7 +254099,7 @@ namespace: uberon def: "Any excreted gas that is produced by the digestive tract." [http://orcid.org/0000-0002-6601-2165] comment: In mammals, mostly produced as a byproduct of bacterial fermentation in the gastrointestinal (GI) tract, especially the colon, and excreted through the rectum synonym: "flatulence" NARROW [FMA:78440] -synonym: "flatus" NARROW LATIN [Wikipedia:Flatulence] +synonym: "flatus" NARROW OMO:0003011 [Wikipedia:Flatulence] synonym: "intestinal gas" NARROW [] xref: FMA:78440 is_a: UBERON:0034945 ! excreted gas @@ -253905,13 +254348,13 @@ intersection_of: part_of UBERON:0001044 ! saliva-secreting gland id: UBERON:0035050 name: excretory duct namespace: uberon +xref: BTO:0006341 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} is_a: UBERON:0000058 ! duct [Term] id: UBERON:0035053 name: interlobular duct of salivary gland namespace: uberon -xref: BTO:0006341 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} xref: FMA:60053 is_a: UBERON:0014716 ! interlobular duct is_a: UBERON:0035049 ! excretory duct of salivary gland @@ -254105,7 +254548,7 @@ name: posterior surface of prostate namespace: uberon def: "The flattened aspect of the prostate with a slight furrow facing the rectum and anus." [ncithesaurus:Posterior_Surface_of_the_Prostate] synonym: "facies posterior (prostatae)" EXACT [FMA:19592] -synonym: "facies posterior prostatae" EXACT LATIN [FMA:19592, FMA:TA] +synonym: "facies posterior prostatae" EXACT OMO:0003011 [FMA:19592, FMA:TA] synonym: "posterior surface of prostate gland" EXACT [FMA:19592] xref: FMA:19592 xref: NCIT:C13095 @@ -254301,7 +254744,7 @@ namespace: uberon def: "The parietal pleura that lines the mediastinum." [ncithesaurus:Mediastinal_Pleura] synonym: "mediastinal part of parietal pleura" EXACT [FMA:9736] synonym: "pars mediastinalis (pleurae)" EXACT [FMA:9736] -synonym: "pars mediastinalis pleurae parietalis" EXACT LATIN [FMA:9736, FMA:TA] +synonym: "pars mediastinalis pleurae parietalis" EXACT OMO:0003011 [FMA:9736, FMA:TA] xref: FMA:9736 xref: NCIT:C94820 xref: SCTID:362002008 @@ -254334,7 +254777,7 @@ id: UBERON:0035471 name: posterior surface of kidney namespace: uberon synonym: "facies posterior (Ren)" EXACT [FMA:15590] -synonym: "facies posterior renis" EXACT LATIN [FMA:15590, FMA:TA] +synonym: "facies posterior renis" EXACT OMO:0003011 [FMA:15590, FMA:TA] xref: FMA:15590 xref: NCIT:C32895 xref: SCTID:279376000 @@ -254387,7 +254830,7 @@ namespace: uberon def: "The aspect of the prostate facing the pubic symphysis." [ncithesaurus:Anterior_Surface_of_the_Prostate] synonym: "anterior surface of prostate gland" EXACT [FMA:19591] synonym: "facies anterior (prostatae)" EXACT [FMA:19591] -synonym: "facies anterior prostatae" EXACT LATIN [FMA:19591, FMA:TA] +synonym: "facies anterior prostatae" EXACT OMO:0003011 [FMA:19591, FMA:TA] xref: FMA:19591 xref: NCIT:C13089 xref: SCTID:279696001 @@ -254643,13 +255086,13 @@ def: "The parts of the orbital region that are outside of the the eyeball, inclu synonym: "accessory parts of orbital region" RELATED [] synonym: "accessory visual structures" RELATED [FMA:76554, Wikipedia:Accessory_visual_structures] synonym: "accessory visual structures set" RELATED [FMA:76554] -synonym: "adnexa oculi" EXACT LATIN [http://medical-dictionary.thefreedictionary.com/ocular+adnexa] +synonym: "adnexa oculi" EXACT OMO:0003011 [http://medical-dictionary.thefreedictionary.com/ocular+adnexa] synonym: "adnexal parts of orbital region" RELATED [] synonym: "appendage of eye" RELATED [http://medical-dictionary.thefreedictionary.com/ocular+adnexa] synonym: "appendages of the eye" RELATED OMO:0003004 [http://medical-dictionary.thefreedictionary.com/ocular+adnexa] synonym: "eye adnexa" RELATED [] synonym: "set of accessory visual structures" RELATED [FMA:76554] -synonym: "structurae oculi accessoriae" RELATED LATIN [Wikipedia:Accessory_visual_structures] +synonym: "structurae oculi accessoriae" RELATED OMO:0003011 [Wikipedia:Accessory_visual_structures] xref: FMA:76554 xref: NCIT:C32574 xref: SCTID:120612006 @@ -254853,7 +255296,7 @@ id: UBERON:0035819 name: abdominopelvic cavity namespace: uberon def: "The part of the ventral body cavity that is within the abdominal segment of the trunk, which encompasses the abdomen proper plus pelvic cavity." [UBERON:cjm] -synonym: "cavitas abdominis et pelvis" EXACT LATIN [FMA:TA] +synonym: "cavitas abdominis et pelvis" EXACT OMO:0003011 [FMA:TA] xref: FMA:12267 xref: Wikipedia:Abdominopelvic_cavity is_a: UBERON:0000464 ! anatomical space @@ -254933,6 +255376,21 @@ intersection_of: UBERON:0000958 ! medulla of organ intersection_of: part_of UBERON:0001233 ! right adrenal gland relationship: part_of UBERON:0001233 ! right adrenal gland +[Term] +id: UBERON:0035831 +name: costal diaphragm +namespace: uberon +def: "The domain of the diaphragm that is a thin domed sheet of muscle composed of a radial array of myofibers extending laterally from the ribs and medially to a central tendon." [PMID:23586979] +synonym: "costal part of diaphragm" EXACT [FMA:58277] +synonym: "pars costalis diaphragmatis" EXACT OMO:0003011 [FMA:TA] +xref: FMA:58277 +xref: SCTID:368048007 +is_a: UBERON:0000063 ! organ subunit +is_a: UBERON:0015212 ! lateral structure +relationship: attaches_to UBERON:0006670 ! central tendon of diaphragm +relationship: in_lateral_side_of UBERON:0001103 {source="PMID:23586979"} ! diaphragm +relationship: part_of UBERON:0001103 {source="PMID:23586979"} ! diaphragm + [Term] id: UBERON:0035927 name: sulcus of parietal lobe @@ -255127,7 +255585,7 @@ namespace: uberon def: "Fluid that lines the vaginal walls that consists of multiple secretions that collect in the vagina from different glands." [http://www.bumc.bu.edu/sexualmedicine/physicianinformation/female-genital-anatomy/] synonym: "vaginal discharge" RELATED [] synonym: "vaginal secretion" RELATED [] -xref: BTO:0003084 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: BTO:0003084 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} is_a: UBERON:0006314 ! bodily fluid intersection_of: UBERON:0006314 ! bodily fluid intersection_of: located_in UBERON:0000996 ! vagina @@ -255206,7 +255664,7 @@ name: zygomaticotemporal nerve namespace: uberon def: "The zygomaticotemporal nerve or zygomaticotemporal branch (temporal branch) is derived from the maxillary branch of the trigeminal nerve (Cranial nerve V). It runs along the lateral wall of the orbit in a groove in the zygomatic bone, receives a branch of communication from the lacrimal, and passes through zygomaticotemporal foramen in the zygomatic bone to enter the temporal fossa. It ascends between the bone, and substance of the Temporalis muscle, pierces the temporal fascia about 2.5 cm. above the zygomatic arch, and is distributed to the skin of the side of the forehead, and communicates with the facial nerve and with the auriculotemporal branch of the mandibular nerve. As it pierces the temporal fascia, it gives off a slender twig, which runs between the two layers of the fascia to the lateral angle of the orbit." [Wikipedia:Zygomaticotemporal_nerve] synonym: "ramus zygomaticotemporalis (Nervus zygomaticus)" EXACT [FMA:52972] -synonym: "ramus zygomaticotemporalis nervus zygomatici" EXACT LATIN [FMA:TA] +synonym: "ramus zygomaticotemporalis nervus zygomatici" EXACT OMO:0003011 [FMA:TA] synonym: "zygomaticotemporal" RELATED [Wikipedia:Zygomaticotemporal_nerve] synonym: "zygomaticotemporal branch" RELATED [Wikipedia:Zygomaticotemporal_nerve] synonym: "zygomaticotemporal branch of zygomatic nerve" EXACT [FMA:52972] @@ -255332,11 +255790,13 @@ id: UBERON:0036295 name: renal pelvis/ureter namespace: uberon def: "The upper tract of the renal system. The renal pelvis is the large cavity in the middle of each kidney. Urine drains from each kidney through a long tube called the ureter, into the bladder, where it is stored until it is passed from the body through the urethra." [NCIT:C54419] +subset: human_reference_atlas synonym: "renal pelvis and ureter" EXACT [] synonym: "renal pelvis plus ureter" EXACT [] xref: NCIT:C54419 is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0011143 {source="NCIT"} ! upper urinary tract +relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: UBERON:0036301 @@ -255751,7 +256211,7 @@ relationship: supplies UBERON:0001264 ! pancreas id: UBERON:0039355 name: urethral artery namespace: uberon -synonym: "arteria urethralis" EXACT LATIN [A12.2.15.042] +synonym: "arteria urethralis" EXACT OMO:0003011 [A12.2.15.042] xref: FMA:20903 is_a: UBERON:0001637 ! artery intersection_of: UBERON:0001637 ! artery @@ -256330,7 +256790,7 @@ name: neck of humerus namespace: uberon synonym: "anatomic neck of humerus" RELATED [FMA:23356] synonym: "collum anatomicum (Humerus)" EXACT [FMA:23356] -synonym: "collum anatomicum humeri" EXACT LATIN [FMA:23356, FMA:TA] +synonym: "collum anatomicum humeri" EXACT OMO:0003011 [FMA:23356, FMA:TA] synonym: "humeral neck" EXACT [] xref: FMA:23356 xref: NCIT:C33164 @@ -256475,7 +256935,7 @@ name: arthropod tagma namespace: uberon def: "One of the main divisions of the whole organism of arthropods formed from groups of segments." [doi:10.1016/B978-0-12-385026-3.00024-3] comment: Strictly speaking the term "tagma" cam be used for any metameric organism, however we follow the common usage which is to restrict the term to arthropods. -xref: FBbt:00000002 +xref: FBbt:00000002 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0011676 ! subdivision of organism along main body axis relationship: never_in_taxon NCBITaxon:7742 ! Vertebrata relationship: only_in_taxon NCBITaxon:6656 ! Arthropoda @@ -256484,7 +256944,7 @@ relationship: only_in_taxon NCBITaxon:6656 ! Arthropoda id: UBERON:6000004 name: panarthropod head namespace: uberon -xref: FBbt:00000004 +xref: FBbt:00000004 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0000033 ! head intersection_of: UBERON:0000033 ! head intersection_of: part_of NCBITaxon:88770 ! Panarthropoda @@ -256495,7 +256955,7 @@ id: UBERON:6000137 name: embryonic tagma namespace: uberon def: "Any tagma (UBERON:6000002) that is part of some embryo (UBERON:6000052)." [FBC:auto_generated_definition] -xref: FBbt:00000137 +xref: FBbt:00000137 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:6000002 ! arthropod tagma intersection_of: UBERON:6000002 ! arthropod tagma intersection_of: part_of UBERON:0000922 ! embryo @@ -256506,7 +256966,7 @@ id: UBERON:6001728 name: insect larval tagma namespace: uberon def: "Any tagma (UBERON:6000002) that is part of some larva (UBERON:6001727)." [FBC:auto_generated_definition] -xref: FBbt:00001728 +xref: FBbt:00001728 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:6000002 ! arthropod tagma intersection_of: UBERON:6000002 ! arthropod tagma intersection_of: part_of UBERON:0002548 ! larva @@ -256517,7 +256977,7 @@ id: UBERON:6001730 name: insect larval head namespace: uberon def: "Any head that is part of some larva." [FBC:auto_generated_definition] -xref: FBbt:00001730 +xref: FBbt:00001730 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0000033 ! head intersection_of: UBERON:0000033 ! head intersection_of: only_in_taxon NCBITaxon:50557 ! Insecta @@ -256531,7 +256991,7 @@ name: insect larval sense organ namespace: uberon def: "Any sense organ that is part of some larva." [FBC:auto_generated_definition] synonym: "larval sense organ" EXACT [] -xref: FBbt:00002639 +xref: FBbt:00002639 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0000020 ! sense organ intersection_of: UBERON:0000020 ! sense organ intersection_of: only_in_taxon NCBITaxon:50557 ! Insecta @@ -256544,7 +257004,7 @@ id: UBERON:6003005 name: insect adult tagma namespace: uberon def: "Any tagma (UBERON:6000002) that is part of some adult (UBERON:6003004)." [FBC:auto_generated_definition] -xref: FBbt:00003005 +xref: FBbt:00003005 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:6000002 ! arthropod tagma intersection_of: UBERON:6000002 ! arthropod tagma intersection_of: part_of UBERON:0007023 ! adult organism @@ -256555,7 +257015,7 @@ id: UBERON:6003007 name: insect adult head namespace: uberon def: "Head of the adult organism." [FBC:SPR] -xref: FBbt:00003007 +xref: FBbt:00003007 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:6000004 ! panarthropod head is_a: UBERON:6003005 ! insect adult tagma intersection_of: UBERON:0000033 ! head @@ -256569,7 +257029,7 @@ name: insect embryonic/larval sensillum namespace: uberon def: "Any sensillum (UBERON:6007152) that is part of some larva (UBERON:6001727)." [FBC:auto_generated_definition] synonym: "larval sensillum" EXACT [] -xref: FBbt:00007240 +xref: FBbt:00007240 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0002536 ! arthropod sensillum is_a: UBERON:6002639 ! insect larval sense organ intersection_of: UBERON:0002536 ! arthropod sensillum @@ -256581,7 +257041,7 @@ name: insect embryonic/larval head sensillum namespace: uberon def: "Any sensillum (UBERON:6007152) that is part of some larval head (UBERON:6001730)." [FBC:auto_generated_definition] synonym: "larval head sensillum" NARROW [] -xref: FBbt:00007242 +xref: FBbt:00007242 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0000963 ! head sensillum is_a: UBERON:6007240 ! insect embryonic/larval sensillum is_a: UBERON:6007280 ! insect embryonic/larval head sense organ @@ -256594,7 +257054,7 @@ name: insect embryonic/larval head sense organ namespace: uberon def: "Any sense organ (UBERON:6005155) that is part of some larval head (UBERON:6001730)." [FBC:auto_generated_definition] synonym: "larval head sense organ" EXACT [] -xref: FBbt:00007280 +xref: FBbt:00007280 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:6002639 ! insect larval sense organ intersection_of: UBERON:0000020 ! sense organ intersection_of: part_of UBERON:6001730 ! insect larval head @@ -256834,7 +257294,7 @@ name: liver serosa namespace: uberon def: "Hepatic serous coat; peritoneal covering of the liver, enclosing almost all except for a triangular area on its posterior surface (the 'bare area of the liver') and a smaller area where the liver and gallbladder are in direct contact." [https://medical-dictionary.thefreedictionary.com/serosa+of+liver, https://orcid.org/0000-0002-0449-2730] synonym: "serosa of liver" EXACT [FMA:15811] -synonym: "tunica serosa hepatis" EXACT [https://medical-dictionary.thefreedictionary.com/serosa+of+liver] {synonymtypedef="LATIN"} +synonym: "tunica serosa hepatis" EXACT OMO:0003011 [https://medical-dictionary.thefreedictionary.com/serosa+of+liver] is_a: UBERON:0000042 ! serous membrane intersection_of: UBERON:0000042 ! serous membrane intersection_of: part_of UBERON:0002107 ! liver @@ -256881,7 +257341,7 @@ subset: human_reference_atlas synonym: "duodeno-jejunal flexure" EXACT [] synonym: "duodenojejunal flexure" EXACT [] synonym: "duodenojejunal junction" EXACT [] -synonym: "flexura duodenojejunalis" EXACT LATIN [Wikipedia:Duodenojejunal_flexure] +synonym: "flexura duodenojejunalis" EXACT OMO:0003011 [Wikipedia:Duodenojejunal_flexure] xref: FMA:15957 xref: https://orcid.org/0000-0003-4183-8865 xref: TA2:2952 @@ -257700,7 +258160,7 @@ name: excretory system namespace: uberon def: "An anatomical system that eliminates waste products that arise as a result of metabolic activity." [GO:0007588] subset: human_reference_atlas -xref: BTO:0006338 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: BTO:0006338 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} is_a: UBERON:0000467 ! anatomical system intersection_of: UBERON:0000467 ! anatomical system intersection_of: capable_of GO:0046903 ! secretion @@ -258083,7 +258543,7 @@ name: chorionic plate blood vessel namespace: uberon def: "A blood vessel that is part of the chorionic plate." [https://www.ncbi.nlm.nih.gov/books/NBK53254/] subset: human_reference_atlas -is_a: UBERON:0001981 ! blood vessel +is_a: UBERON:0022358 ! placenta blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0004027 ! chorionic plate relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 @@ -258091,6 +258551,21 @@ relationship: part_of UBERON:0004027 ! chorionic plate relationship: present_in_taxon NCBITaxon:9606 ! Homo sapiens property_value: dcterms-date "2023-09-14T09:09:36Z" xsd:dateTime +[Term] +id: UBERON:8600023 +name: placental villous stroma +namespace: uberon +def: "A stroma that is part of a chorionic villus (placental villus). A placental villous stroma supports the fetal capillaries and villous trophoblast." [PMID:31512233] +synonym: "chorionic villous stroma" EXACT [PMID:12624135] +synonym: "CVS" RELATED OMO:0003000 [PMID:12624135] +is_a: UBERON:0003891 ! stroma +intersection_of: UBERON:0003891 ! stroma +intersection_of: part_of UBERON:0007106 ! chorionic villus +relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 +relationship: dc-contributor https://orcid.org/0000-0001-7655-4833 +relationship: part_of UBERON:0007106 ! chorionic villus +property_value: dcterms-date "2023-07-04T10:46:17Z" xsd:dateTime + [Term] id: UBERON:8600024 name: pulmonary venule @@ -258107,6 +258582,74 @@ relationship: drains UBERON:0016405 ! pulmonary capillary relationship: part_of UBERON:0013127 ! pulmonary venous system property_value: dcterms-date "2023-10-24T11:26:27Z" xsd:dateTime +[Term] +id: UBERON:8600034 +name: jejunum lamina propria +namespace: uberon +def: "A lamina propria that is part of a jejunum." [PMID:9394954] +synonym: "jejunal lamina propria" EXACT [PMID:1556433] +synonym: "lamina propria of jejunum" EXACT [PMID:22763879] +is_a: UBERON:0001238 ! lamina propria of small intestine +intersection_of: UBERON:0000030 ! lamina propria +intersection_of: part_of UBERON:0002115 ! jejunum +relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 +relationship: dc-contributor https://orcid.org/0000-0001-8134-3037 +relationship: part_of UBERON:0008343 ! intestinal villus of jejunum +property_value: dcterms-date "2024-01-09T16:36:35Z" xsd:dateTime + +[Term] +id: UBERON:8600035 +name: ileum lamina propria +namespace: uberon +def: "A lamina propria that is part of an ileum." [PMID:29316348] +synonym: "ileal lamina propria" EXACT [PMID:37467267] +synonym: "lamina propria of ileum" EXACT [PMID:36067905] +is_a: UBERON:0001238 ! lamina propria of small intestine +intersection_of: UBERON:0000030 ! lamina propria +intersection_of: part_of UBERON:0002116 ! ileum +relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 +relationship: dc-contributor https://orcid.org/0000-0001-8134-3037 +relationship: part_of UBERON:0008344 ! intestinal villus of ileum +property_value: dcterms-date "2024-01-09T16:48:17Z" xsd:dateTime + +[Term] +id: UBERON:8600038 +name: placental disc +namespace: uberon +def: "A disc-shaped structure that is part of the placenta. A placental disc supports fetal development through the exchange of nutrients between maternal and fetal bloodstreams. The placental disc is structured to keep the blood streams separate, while maximizing surface area for the transport of nutrients between them, to maintain an immunological barrier." [PMID:35496035] +synonym: "placental disk" EXACT [PMID:30133439] +is_a: UBERON:0000061 ! anatomical structure +relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 +relationship: part_of UBERON:0001987 ! placenta +property_value: dcterms-date "2024-01-16T17:50:20Z" xsd:dateTime + +[Term] +id: UBERON:8600039 +name: chorionic villous mesenchyme +namespace: uberon +def: "A mesenchyme that is part of a chorionic villus." [doi:10.1007/978-3-030-84725-8] +is_a: UBERON:0002050 ! embryonic structure +is_a: UBERON:0003265 ! chorionic mesenchyme +is_a: UBERON:0005291 ! embryonic tissue +intersection_of: UBERON:0003104 ! mesenchyme +intersection_of: part_of UBERON:0007106 ! chorionic villus +relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 +relationship: part_of UBERON:0007106 ! chorionic villus +property_value: dcterms-date "2024-01-16T18:13:12Z" xsd:dateTime + +[Term] +id: UBERON:8600042 +name: endometrial lymphatic vessel +namespace: uberon +def: "A lymphatic vessel that is part of an endometrium." [PMID:23054374] +is_a: UBERON:0001473 ! lymphatic vessel +is_a: UBERON:0005156 ! reproductive structure +intersection_of: UBERON:0001473 ! lymphatic vessel +intersection_of: part_of UBERON:0001295 ! endometrium +relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 +relationship: part_of UBERON:0001295 ! endometrium +property_value: dcterms-date "2024-01-16T18:18:36Z" xsd:dateTime + [Term] id: http://purl.obolibrary.org/obo/D96882F1-8709-49AB-BCA9-772A67EA6C33 name: obsolete D96882F1-8709-49AB-BCA9-772A67EA6C33 @@ -258499,20 +259042,6 @@ property_value: seeAlso "https://github.com/obophenotype/uberon/wiki/Part-disjoi is_a: RO:0002323 ! mereotopologically related to expand_expression_to: "BFO_0000051 exactly 0 (BFO_0000050 some ?Y)" [] -[Typedef] -id: RO:0002203 -name: develops into -def: "inverse of develops from" [] -subset: RO:0002259 -property_value: IAO:0000114 IAO:0000125 -property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 -property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172 -property_value: IAO:0000117 https://orcid.org/0000-0003-1980-3228 -is_transitive: true -is_a: has_potential_to_develop_into ! has potential to develop into -is_a: RO:0002286 ! developmentally succeeded by -is_a: RO:0002388 ! has potential to directly develop into - [Typedef] id: RO:0002206 name: expressed in @@ -258533,7 +259062,7 @@ def: "inverse of directly develops from" [] subset: RO:0002259 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000118 "developmental precursor of" xsd:string -is_a: RO:0002203 ! develops into +is_a: develops_into ! develops into [Typedef] id: RO:0002222 @@ -258563,7 +259092,7 @@ def: "inverse of has developmental contribution from" [] subset: RO:0002259 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 -holds_over_chain: RO:0002203 part_of +holds_over_chain: develops_into part_of is_a: has_potential_to_developmentally_contribute_to ! has potential to developmentally contribute to is_a: RO:0002286 ! developmentally succeeded by @@ -259849,7 +260378,7 @@ range: BFO:0000004 ! independent continuant is_transitive: true is_a: has_developmental_contribution_from ! has developmental contribution from is_a: RO:0002258 ! developmentally preceded by -inverse_of: RO:0002203 ! develops into +inverse_of: develops_into ! develops into [Typedef] id: develops_from_part_of @@ -259876,6 +260405,22 @@ domain: UBERON:0001062 ! anatomical entity holds_over_chain: directly_develops_from located_in is_a: RO:0002258 ! developmentally preceded by +[Typedef] +id: develops_into +name: develops into +namespace: uberon +def: "inverse of develops from" [] +subset: RO:0002259 +xref: RO:0002203 +property_value: IAO:0000114 IAO:0000125 +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 +property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172 +property_value: IAO:0000117 https://orcid.org/0000-0003-1980-3228 +is_transitive: true +is_a: has_potential_to_develop_into ! has potential to develop into +is_a: RO:0002286 ! developmentally succeeded by +is_a: RO:0002388 ! has potential to directly develop into + [Typedef] id: directly_develops_from name: directly develops from @@ -260211,7 +260756,7 @@ is_a: RO:0002479 ! has part that occurs in id: has_high_plasma_membrane_amount name: obsolete has_high_plasma_membrane_amount def: "OBSOLETE A relation between a cell and molecule or complex such that every instance of the cell has a high number of instances of that molecule expressed on the cell surface. For the formal definition, see Masci et al (PMID:19243617)." [PMID:19243617] -comment: Replaced with RO:0015015, see https://github.com/obophenotype/cell-ontology/issues/1481 +property_value: term_tracker_item https://github.com/obophenotype/cell-ontology/issues/1481 is_obsolete: true replaced_by: RO:0015015 @@ -260238,7 +260783,7 @@ inverse_of: input_of ! input of id: has_low_plasma_membrane_amount name: obsolete has_low_plasma_membrane_amount def: "OBSOLETE A relation between a cell and molecule or complex such that every instance of the cell has a low number of instances of that molecule expressed on the cell surface. For the formal definition, see Masci et al (PMID:19243617)." [PMID:19243617] -comment: Replaced with RO:0015016, see https://github.com/obophenotype/cell-ontology/issues/1481 +property_value: term_tracker_item https://github.com/obophenotype/cell-ontology/issues/1481 is_obsolete: true replaced_by: RO:0015016 @@ -261629,21 +262174,21 @@ is_a: develops_from ! develops from id: transitively_anteriorly_connected_to name: transitively anteriorly connected to namespace: uberon -def: "." [http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern] +property_value: seeAlso "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" xsd:anyURI is_transitive: true [Typedef] id: transitively_distally_connected_to name: transitively distally connected to namespace: uberon -def: "." [http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern] +property_value: seeAlso "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" xsd:anyURI is_transitive: true [Typedef] id: transitively_proximally_connected_to name: transitively proximally connected to namespace: uberon -def: "." [http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern] +property_value: seeAlso "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" xsd:anyURI is_transitive: true [Typedef] diff --git a/patterns/definitions.owl b/patterns/definitions.owl index 34b1cf8a3..046777e53 100644 --- a/patterns/definitions.owl +++ b/patterns/definitions.owl @@ -7,8 +7,8 @@ Prefix(rdfs:=) Ontology( - -Annotation(owl:versionInfo "2023-12-05") + +Annotation(owl:versionInfo "2024-02-13") diff --git a/src/ontology/diffs/cl-diff.md b/src/ontology/diffs/cl-diff.md index 13d17eefc..0cb2eaef3 100644 --- a/src/ontology/diffs/cl-diff.md +++ b/src/ontology/diffs/cl-diff.md @@ -2,12 +2,12 @@ ## Left - Ontology IRI: `http://purl.obolibrary.org/obo/cl.owl` -- Version IRI: `http://purl.obolibrary.org/obo/cl/releases/2023-12-05/cl.owl` +- Version IRI: `http://purl.obolibrary.org/obo/cl/releases/2024-01-04/cl.owl` - Loaded from: `http://purl.obolibrary.org/obo/cl.owl` ## Right - Ontology IRI: `http://purl.obolibrary.org/obo/cl.owl` -- Version IRI: `http://purl.obolibrary.org/obo/cl/releases/2024-01-04/cl.owl` +- Version IRI: `http://purl.obolibrary.org/obo/cl/releases/2024-02-13/cl.owl` - Loaded from: `file:/work/src/ontology/../../cl.owl` ### Ontology imports @@ -16,1466 +16,27587 @@ ### Ontology annotations #### Removed -- [versionInfo](http://www.w3.org/2002/07/owl#versionInfo) "2023-12-05" +- [versionInfo](http://www.w3.org/2002/07/owl#versionInfo) "2024-01-04" #### Added -- [versionInfo](http://www.w3.org/2002/07/owl#versionInfo) "2024-01-04" +- [versionInfo](http://www.w3.org/2002/07/owl#versionInfo) "2024-02-13" + + +### A2 amacrine cell `http://purl.obolibrary.org/obo/CL_0004219` + +#### Added +- [A2 amacrine cell](http://purl.obolibrary.org/obo/CL_0004219) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### Ammon's horn `http://purl.obolibrary.org/obo/UBERON_0001954` +#### Removed +- [Ammon's horn](http://purl.obolibrary.org/obo/UBERON_0001954) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "hippocampus proprius" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:62493" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [Ammon's horn](http://purl.obolibrary.org/obo/UBERON_0001954) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "hippocampus proprius" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:62493" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### B cell `http://purl.obolibrary.org/obo/CL_0000236` + +#### Added +- [B cell](http://purl.obolibrary.org/obo/CL_0000236) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### B-1 B cell `http://purl.obolibrary.org/obo/CL_0000819` + +#### Added +- [B-1 B cell](http://purl.obolibrary.org/obo/CL_0000819) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### B-1a B cell `http://purl.obolibrary.org/obo/CL_0000820` + +#### Added +- [B-1a B cell](http://purl.obolibrary.org/obo/CL_0000820) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### B-1b B cell `http://purl.obolibrary.org/obo/CL_0000821` + +#### Added +- [B-1b B cell](http://purl.obolibrary.org/obo/CL_0000821) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### B-2 B cell `http://purl.obolibrary.org/obo/CL_0000822` + +#### Added +- [B-2 B cell](http://purl.obolibrary.org/obo/CL_0000822) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### BEST4+ intestinal epithelial cell, human `http://purl.obolibrary.org/obo/CL_4030026` + +#### Added +- [BEST4+ intestinal epithelial cell, human](http://purl.obolibrary.org/obo/CL_4030026) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### Bergmann glial cell `http://purl.obolibrary.org/obo/CL_0000644` + +#### Added +- [Bergmann glial cell](http://purl.obolibrary.org/obo/CL_0000644) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### CD14-low, CD16-positive monocyte `http://purl.obolibrary.org/obo/CL_0002396` + +#### Added +- [CD14-low, CD16-positive monocyte](http://purl.obolibrary.org/obo/CL_0002396) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### CD14-positive monocyte `http://purl.obolibrary.org/obo/CL_0001054` + +#### Added +- [CD14-positive monocyte](http://purl.obolibrary.org/obo/CL_0001054) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### CD14-positive, CD16-negative classical monocyte `http://purl.obolibrary.org/obo/CL_0002057` + +#### Added +- [CD14-positive, CD16-negative classical monocyte](http://purl.obolibrary.org/obo/CL_0002057) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### CD14-positive, CD16-positive monocyte `http://purl.obolibrary.org/obo/CL_0002397` + +#### Added +- [CD14-positive, CD16-positive monocyte](http://purl.obolibrary.org/obo/CL_0002397) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### CD141-positive myeloid dendritic cell `http://purl.obolibrary.org/obo/CL_0002394` + +#### Added +- [CD141-positive myeloid dendritic cell](http://purl.obolibrary.org/obo/CL_0002394) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### CD16-negative, CD56-bright natural killer cell, human `http://purl.obolibrary.org/obo/CL_0000938` + +#### Added +- [CD16-negative, CD56-bright natural killer cell, human](http://purl.obolibrary.org/obo/CL_0000938) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### CD16-positive, CD56-dim natural killer cell, human `http://purl.obolibrary.org/obo/CL_0000939` + +#### Added +- [CD16-positive, CD56-dim natural killer cell, human](http://purl.obolibrary.org/obo/CL_0000939) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### CD1c-positive myeloid dendritic cell `http://purl.obolibrary.org/obo/CL_0002399` + +#### Added +- [CD1c-positive myeloid dendritic cell](http://purl.obolibrary.org/obo/CL_0002399) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### CD34-positive, CD38-negative hematopoietic stem cell `http://purl.obolibrary.org/obo/CL_0001024` + +#### Added +- [CD34-positive, CD38-negative hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0001024) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### CD34-positive, CD56-positive, CD117-positive common innate lymphoid precursor, human `http://purl.obolibrary.org/obo/CL_0001074` + +#### Added +- [CD34-positive, CD56-positive, CD117-positive common innate lymphoid precursor, human](http://purl.obolibrary.org/obo/CL_0001074) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### CD4-positive helper T cell `http://purl.obolibrary.org/obo/CL_0000492` + +#### Added +- [CD4-positive helper T cell](http://purl.obolibrary.org/obo/CL_0000492) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### CD4-positive, CD25-positive, alpha-beta regulatory T cell `http://purl.obolibrary.org/obo/CL_0000792` + +#### Added +- [CD4-positive, CD25-positive, alpha-beta regulatory T cell](http://purl.obolibrary.org/obo/CL_0000792) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### CD4-positive, alpha-beta T cell `http://purl.obolibrary.org/obo/CL_0000624` + +#### Added +- [CD4-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000624) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### CD4-positive, alpha-beta cytotoxic T cell `http://purl.obolibrary.org/obo/CL_0000934` + +#### Added +- [CD4-positive, alpha-beta cytotoxic T cell](http://purl.obolibrary.org/obo/CL_0000934) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### CD4-positive, alpha-beta memory T cell `http://purl.obolibrary.org/obo/CL_0000897` + +#### Added +- [CD4-positive, alpha-beta memory T cell](http://purl.obolibrary.org/obo/CL_0000897) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### CD4-positive, alpha-beta thymocyte `http://purl.obolibrary.org/obo/CL_0000810` + +#### Added +- [CD4-positive, alpha-beta thymocyte](http://purl.obolibrary.org/obo/CL_0000810) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### CD56-positive, CD161-positive immature natural killer cell, human `http://purl.obolibrary.org/obo/CL_0002338` + +#### Added +- [CD56-positive, CD161-positive immature natural killer cell, human](http://purl.obolibrary.org/obo/CL_0002338) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### CD8-alpha alpha positive, gamma-delta intraepithelial T cell `http://purl.obolibrary.org/obo/CL_0000802` + +#### Added +- [CD8-alpha alpha positive, gamma-delta intraepithelial T cell](http://purl.obolibrary.org/obo/CL_0000802) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell `http://purl.obolibrary.org/obo/CL_0000915` + +#### Added +- [CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell](http://purl.obolibrary.org/obo/CL_0000915) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### CD8-alpha-beta-positive, alpha-beta intraepithelial T cell `http://purl.obolibrary.org/obo/CL_0000796` + +#### Added +- [CD8-alpha-beta-positive, alpha-beta intraepithelial T cell](http://purl.obolibrary.org/obo/CL_0000796) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### CD8-positive, alpha-beta T cell `http://purl.obolibrary.org/obo/CL_0000625` + +#### Added +- [CD8-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000625) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### CD8-positive, alpha-beta cytokine secreting effector T cell `http://purl.obolibrary.org/obo/CL_0000908` + +#### Added +- [CD8-positive, alpha-beta cytokine secreting effector T cell](http://purl.obolibrary.org/obo/CL_0000908) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### CD8-positive, alpha-beta cytotoxic T cell `http://purl.obolibrary.org/obo/CL_0000794` + +#### Added +- [CD8-positive, alpha-beta cytotoxic T cell](http://purl.obolibrary.org/obo/CL_0000794) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### CD8-positive, alpha-beta memory T cell `http://purl.obolibrary.org/obo/CL_0000909` + +#### Added +- [CD8-positive, alpha-beta memory T cell](http://purl.obolibrary.org/obo/CL_0000909) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### CD8-positive, alpha-beta memory T cell, CD45RO-positive `http://purl.obolibrary.org/obo/CL_0001203` + +#### Added +- [CD8-positive, alpha-beta memory T cell, CD45RO-positive](http://purl.obolibrary.org/obo/CL_0001203) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### CD8-positive, alpha-beta thymocyte `http://purl.obolibrary.org/obo/CL_0000811` + +#### Added +- [CD8-positive, alpha-beta thymocyte](http://purl.obolibrary.org/obo/CL_0000811) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### CHEBI_16480 `http://purl.obolibrary.org/obo/CHEBI_16480` +#### Removed +- Class: [CHEBI_16480](http://purl.obolibrary.org/obo/CHEBI_16480) -### Actinopterygii `http://purl.obolibrary.org/obo/NCBITaxon_7898` + +### CHEBI_35238 `http://purl.obolibrary.org/obo/CHEBI_35238` + +#### Added +- Class: [CHEBI_35238](http://purl.obolibrary.org/obo/CHEBI_35238) + + +### CHEBI_37022 `http://purl.obolibrary.org/obo/CHEBI_37022` #### Removed -- [Actinopterygii](http://purl.obolibrary.org/obo/NCBITaxon_7898) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "fishes" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [common_name](http://purl.obolibrary.org/obo/ncbitaxon#common_name) +- Class: [CHEBI_37022](http://purl.obolibrary.org/obo/CHEBI_37022) + + + +### Cajal-Retzius cell `http://purl.obolibrary.org/obo/CL_0000695` + +#### Added +- [Cajal-Retzius cell](http://purl.obolibrary.org/obo/CL_0000695) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### DN1 thymic pro-T cell `http://purl.obolibrary.org/obo/CL_0000894` + +#### Added +- [DN1 thymic pro-T cell](http://purl.obolibrary.org/obo/CL_0000894) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### DN3 thymocyte `http://purl.obolibrary.org/obo/CL_0000807` + +#### Added +- [DN3 thymocyte](http://purl.obolibrary.org/obo/CL_0000807) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) -- [Actinopterygii](http://purl.obolibrary.org/obo/NCBITaxon_7898) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "fish" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [common_name](http://purl.obolibrary.org/obo/ncbitaxon#common_name) + +### DN4 thymocyte `http://purl.obolibrary.org/obo/CL_0000808` #### Added -- [Actinopterygii](http://purl.obolibrary.org/obo/NCBITaxon_7898) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "fish" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003003](http://purl.obolibrary.org/obo/OMO_0003003) +- [DN4 thymocyte](http://purl.obolibrary.org/obo/CL_0000808) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + -- [Actinopterygii](http://purl.obolibrary.org/obo/NCBITaxon_7898) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "fishes" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003003](http://purl.obolibrary.org/obo/OMO_0003003) +### DNA binding `http://purl.obolibrary.org/obo/GO_0003677` +#### Removed +- [DNA binding](http://purl.obolibrary.org/obo/GO_0003677) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [prokaryote_subset](http://purl.obolibrary.org/obo/go#prokaryote_subset) + +#### Added +- [DNA binding](http://purl.obolibrary.org/obo/GO_0003677) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_prokaryote](http://purl.obolibrary.org/obo/go#goslim_prokaryote) -### Ascomycota `http://purl.obolibrary.org/obo/NCBITaxon_4890` +### DNA recombination `http://purl.obolibrary.org/obo/GO_0006310` #### Removed -- [Ascomycota](http://purl.obolibrary.org/obo/NCBITaxon_4890) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sac fungi" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [common_name](http://purl.obolibrary.org/obo/ncbitaxon#common_name) +- [DNA recombination](http://purl.obolibrary.org/obo/GO_0006310) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [prokaryote_subset](http://purl.obolibrary.org/obo/go#prokaryote_subset) #### Added -- [Ascomycota](http://purl.obolibrary.org/obo/NCBITaxon_4890) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sac fungi" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003003](http://purl.obolibrary.org/obo/OMO_0003003) +- [DNA recombination](http://purl.obolibrary.org/obo/GO_0006310) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_prokaryote](http://purl.obolibrary.org/obo/go#goslim_prokaryote) + + +### DUBIOUS `http://purl.obolibrary.org/obo/uberon/core#DUBIOUS` +#### Removed +- AnnotationProperty: [DUBIOUS](http://purl.obolibrary.org/obo/uberon/core#DUBIOUS) + +- [DUBIOUS](http://purl.obolibrary.org/obo/uberon/core#DUBIOUS) SubPropertyOf: [synonym_type_property](http://www.geneontology.org/formats/oboInOwl#SynonymTypeProperty) + -### Callithrix jacchus `http://purl.obolibrary.org/obo/NCBITaxon_9483` +### Descemet's membrane `http://purl.obolibrary.org/obo/UBERON_0004367` #### Removed -- [Callithrix jacchus](http://purl.obolibrary.org/obo/NCBITaxon_9483) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "white ear-tufted marmoset" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [common_name](http://purl.obolibrary.org/obo/ncbitaxon#common_name) +- [Descemet's membrane](http://purl.obolibrary.org/obo/UBERON_0004367) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lamina limitans posterior corneae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:58309" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [Descemet's membrane](http://purl.obolibrary.org/obo/UBERON_0004367) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lamina limitans posterior corneae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:58309" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### GABAergic amacrine cell `http://purl.obolibrary.org/obo/CL_4030027` + +#### Added +- [GABAergic amacrine cell](http://purl.obolibrary.org/obo/CL_4030027) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### GABAergic neuron `http://purl.obolibrary.org/obo/CL_0000617` + +#### Added +- [GABAergic neuron](http://purl.obolibrary.org/obo/CL_0000617) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### GCIs + +#### Added +- [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [embryo stage](http://purl.obolibrary.org/obo/UBERON_0000068) DisjointWith [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [post-embryonic stage](http://purl.obolibrary.org/obo/UBERON_0000092) + +- [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [hypodermis](http://purl.obolibrary.org/obo/UBERON_0002072) DisjointWith [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [skin of body](http://purl.obolibrary.org/obo/UBERON_0002097) + +- [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [respiratory primordium epithelium](http://purl.obolibrary.org/obo/UBERON_0036072) DisjointWith [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [respiratory primordium mesenchyme](http://purl.obolibrary.org/obo/UBERON_0036073) + +- DisjointClasses: [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [sebaceous gland](http://purl.obolibrary.org/obo/UBERON_0001821), [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [arrector muscle of hair](http://purl.obolibrary.org/obo/UBERON_0002033), [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [hair follicle](http://purl.obolibrary.org/obo/UBERON_0002073) + +- DisjointClasses: [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [central tendon of diaphragm](http://purl.obolibrary.org/obo/UBERON_0006670), [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [crus of diaphragm](http://purl.obolibrary.org/obo/UBERON_0014765), [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [costal diaphragm](http://purl.obolibrary.org/obo/UBERON_0035831) + +- [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [parietal pleura](http://purl.obolibrary.org/obo/UBERON_0002400) DisjointWith [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [visceral pleura](http://purl.obolibrary.org/obo/UBERON_0002401) + +- DisjointClasses: [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [dentate gyrus of hippocampal formation](http://purl.obolibrary.org/obo/UBERON_0001885), [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [Ammon's horn](http://purl.obolibrary.org/obo/UBERON_0001954), [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [subiculum](http://purl.obolibrary.org/obo/UBERON_0002191) + +- [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [right lung](http://purl.obolibrary.org/obo/UBERON_0002167) DisjointWith [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [left lung](http://purl.obolibrary.org/obo/UBERON_0002168) + +- [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [eyeball of camera-type eye](http://purl.obolibrary.org/obo/UBERON_0010230) DisjointWith [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [ocular adnexa](http://purl.obolibrary.org/obo/UBERON_0035639) + +- [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [cortex of hair](http://purl.obolibrary.org/obo/UBERON_0002077) DisjointWith [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [hair medulla](http://purl.obolibrary.org/obo/UBERON_0005184) + +- [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [peritoneal cavity](http://purl.obolibrary.org/obo/UBERON_0001179) DisjointWith [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [peritoneum](http://purl.obolibrary.org/obo/UBERON_0002358) + +- [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [parietal serous pericardium](http://purl.obolibrary.org/obo/UBERON_0002408) DisjointWith [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [visceral serous pericardium](http://purl.obolibrary.org/obo/UBERON_0002425) + +- [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [pleura](http://purl.obolibrary.org/obo/UBERON_0000977) DisjointWith [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [pleural cavity](http://purl.obolibrary.org/obo/UBERON_0002402) + +- [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [peripheral nervous system](http://purl.obolibrary.org/obo/UBERON_0000010) DisjointWith [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [central nervous system](http://purl.obolibrary.org/obo/UBERON_0001017) + +- [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [abdominal cavity](http://purl.obolibrary.org/obo/UBERON_0003684) DisjointWith [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [pelvic cavity](http://purl.obolibrary.org/obo/UBERON_0008203) + +- [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [left dorsal aorta](http://purl.obolibrary.org/obo/UBERON_0005613) DisjointWith [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [right dorsal aorta](http://purl.obolibrary.org/obo/UBERON_0005622) + +- DisjointClasses: [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [submucosa](http://purl.obolibrary.org/obo/UBERON_0000009), [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [mucosa](http://purl.obolibrary.org/obo/UBERON_0000344), [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [hypodermis](http://purl.obolibrary.org/obo/UBERON_0002072), [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [skin of body](http://purl.obolibrary.org/obo/UBERON_0002097) + +- ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [peritoneal cavity](http://purl.obolibrary.org/obo/UBERON_0001179)) or ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [peritoneum](http://purl.obolibrary.org/obo/UBERON_0002358)) EquivalentTo [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [peritoneal sac](http://purl.obolibrary.org/obo/UBERON_0035820) + +- ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [submucosa](http://purl.obolibrary.org/obo/UBERON_0000009)) or ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [mucosa](http://purl.obolibrary.org/obo/UBERON_0000344)) or ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [hypodermis](http://purl.obolibrary.org/obo/UBERON_0002072)) or ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [skin of body](http://purl.obolibrary.org/obo/UBERON_0002097)) EquivalentTo [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [dermatological-muscosal system](http://purl.obolibrary.org/obo/UBERON_0012125) + +- ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [cortex of hair](http://purl.obolibrary.org/obo/UBERON_0002077)) or ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [hair medulla](http://purl.obolibrary.org/obo/UBERON_0005184)) EquivalentTo [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [hair shaft](http://purl.obolibrary.org/obo/UBERON_0002074) + +- ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [left dorsal aorta](http://purl.obolibrary.org/obo/UBERON_0005613)) or ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [right dorsal aorta](http://purl.obolibrary.org/obo/UBERON_0005622)) EquivalentTo [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [pair of dorsal aortae](http://purl.obolibrary.org/obo/UBERON_0010190) + +- ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [respiratory primordium epithelium](http://purl.obolibrary.org/obo/UBERON_0036072)) or ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [respiratory primordium mesenchyme](http://purl.obolibrary.org/obo/UBERON_0036073)) EquivalentTo [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [respiratory primordium](http://purl.obolibrary.org/obo/UBERON_0008947) + +- ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [abdominal cavity](http://purl.obolibrary.org/obo/UBERON_0003684)) or ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [pelvic cavity](http://purl.obolibrary.org/obo/UBERON_0008203)) EquivalentTo [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [abdominopelvic cavity](http://purl.obolibrary.org/obo/UBERON_0035819) + +- ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [eyeball of camera-type eye](http://purl.obolibrary.org/obo/UBERON_0010230)) or ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [ocular adnexa](http://purl.obolibrary.org/obo/UBERON_0035639)) EquivalentTo [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [orbital region](http://purl.obolibrary.org/obo/UBERON_0004088) + +- ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [peripheral nervous system](http://purl.obolibrary.org/obo/UBERON_0000010)) or ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [central nervous system](http://purl.obolibrary.org/obo/UBERON_0001017)) EquivalentTo [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [nervous system](http://purl.obolibrary.org/obo/UBERON_0001016) + +- ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [central tendon of diaphragm](http://purl.obolibrary.org/obo/UBERON_0006670)) or ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [crus of diaphragm](http://purl.obolibrary.org/obo/UBERON_0014765)) or ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [costal diaphragm](http://purl.obolibrary.org/obo/UBERON_0035831)) EquivalentTo [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [diaphragm](http://purl.obolibrary.org/obo/UBERON_0001103) + +- ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [parietal pleura](http://purl.obolibrary.org/obo/UBERON_0002400)) or ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [visceral pleura](http://purl.obolibrary.org/obo/UBERON_0002401)) EquivalentTo [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [pleura](http://purl.obolibrary.org/obo/UBERON_0000977) + +- ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [hypodermis](http://purl.obolibrary.org/obo/UBERON_0002072)) or ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [skin of body](http://purl.obolibrary.org/obo/UBERON_0002097)) EquivalentTo [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [integument](http://purl.obolibrary.org/obo/UBERON_0002199) + +- ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [right lung](http://purl.obolibrary.org/obo/UBERON_0002167)) or ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [left lung](http://purl.obolibrary.org/obo/UBERON_0002168)) EquivalentTo [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [pair of lungs](http://purl.obolibrary.org/obo/UBERON_0000170) + +- ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [pleura](http://purl.obolibrary.org/obo/UBERON_0000977)) or ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [pleural cavity](http://purl.obolibrary.org/obo/UBERON_0002402)) EquivalentTo [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [pleural sac](http://purl.obolibrary.org/obo/UBERON_0009778) + +- ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [parietal serous pericardium](http://purl.obolibrary.org/obo/UBERON_0002408)) or ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [visceral serous pericardium](http://purl.obolibrary.org/obo/UBERON_0002425)) EquivalentTo [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [serous pericardium](http://purl.obolibrary.org/obo/UBERON_0002357) + +- ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [dentate gyrus of hippocampal formation](http://purl.obolibrary.org/obo/UBERON_0001885)) or ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [Ammon's horn](http://purl.obolibrary.org/obo/UBERON_0001954)) or ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [subiculum](http://purl.obolibrary.org/obo/UBERON_0002191)) EquivalentTo [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [hippocampal formation](http://purl.obolibrary.org/obo/UBERON_0002421) + +- ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [embryo stage](http://purl.obolibrary.org/obo/UBERON_0000068)) or ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [post-embryonic stage](http://purl.obolibrary.org/obo/UBERON_0000092)) EquivalentTo [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [life cycle](http://purl.obolibrary.org/obo/UBERON_0000104) + +- ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [sebaceous gland](http://purl.obolibrary.org/obo/UBERON_0001821)) or ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [arrector muscle of hair](http://purl.obolibrary.org/obo/UBERON_0002033)) or ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [hair follicle](http://purl.obolibrary.org/obo/UBERON_0002073)) EquivalentTo [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [pilosebaceous unit](http://purl.obolibrary.org/obo/UBERON_0011932) + + +### GIP cell `http://purl.obolibrary.org/obo/CL_0002278` + +#### Added +- [GIP cell](http://purl.obolibrary.org/obo/CL_0002278) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### Hofbauer cell `http://purl.obolibrary.org/obo/CL_3000001` + +#### Added +- [Hofbauer cell](http://purl.obolibrary.org/obo/CL_3000001) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### ILC1, human `http://purl.obolibrary.org/obo/CL_0001077` + +#### Added +- [ILC1, human](http://purl.obolibrary.org/obo/CL_0001077) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### IgA plasma cell `http://purl.obolibrary.org/obo/CL_0000987` + +#### Added +- [IgA plasma cell](http://purl.obolibrary.org/obo/CL_0000987) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### IgA plasmablast `http://purl.obolibrary.org/obo/CL_0000984` + +#### Added +- [IgA plasmablast](http://purl.obolibrary.org/obo/CL_0000984) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### IgG memory B cell `http://purl.obolibrary.org/obo/CL_0000979` + +#### Added +- [IgG memory B cell](http://purl.obolibrary.org/obo/CL_0000979) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### IgG plasma cell `http://purl.obolibrary.org/obo/CL_0000985` + +#### Added +- [IgG plasma cell](http://purl.obolibrary.org/obo/CL_0000985) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### IgG plasmablast `http://purl.obolibrary.org/obo/CL_0000982` + +#### Added +- [IgG plasmablast](http://purl.obolibrary.org/obo/CL_0000982) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### IgG-negative class switched memory B cell `http://purl.obolibrary.org/obo/CL_0002117` + +#### Added +- [IgG-negative class switched memory B cell](http://purl.obolibrary.org/obo/CL_0002117) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### IgM plasma cell `http://purl.obolibrary.org/obo/CL_0000986` + +#### Added +- [IgM plasma cell](http://purl.obolibrary.org/obo/CL_0000986) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### Kupffer cell `http://purl.obolibrary.org/obo/CL_0000091` + +#### Added +- [Kupffer cell](http://purl.obolibrary.org/obo/CL_0000091) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### L2/3 intratelencephalic projecting glutamatergic neuron of the primary motor cortex `http://purl.obolibrary.org/obo/CL_4023047` + +#### Added +- [L2/3 intratelencephalic projecting glutamatergic neuron of the primary motor cortex](http://purl.obolibrary.org/obo/CL_4023047) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### L2/3-6 intratelencephalic projecting glutamatergic neuron `http://purl.obolibrary.org/obo/CL_4023040` + +#### Added +- [L2/3-6 intratelencephalic projecting glutamatergic neuron](http://purl.obolibrary.org/obo/CL_4023040) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### L4/5 intratelencephalic projecting glutamatergic neuron of the primary motor cortex `http://purl.obolibrary.org/obo/CL_4023048` + +#### Added +- [L4/5 intratelencephalic projecting glutamatergic neuron of the primary motor cortex](http://purl.obolibrary.org/obo/CL_4023048) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### L5 extratelencephalic projecting glutamatergic cortical neuron `http://purl.obolibrary.org/obo/CL_4023041` + +#### Added +- [L5 extratelencephalic projecting glutamatergic cortical neuron](http://purl.obolibrary.org/obo/CL_4023041) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### L5/6 near-projecting glutamatergic neuron of the primary motor cortex `http://purl.obolibrary.org/obo/CL_4023043` + +#### Added +- [L5/6 near-projecting glutamatergic neuron of the primary motor cortex](http://purl.obolibrary.org/obo/CL_4023043) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### L6 corticothalamic-projecting glutamatergic cortical neuron `http://purl.obolibrary.org/obo/CL_4023042` + +#### Added +- [L6 corticothalamic-projecting glutamatergic cortical neuron](http://purl.obolibrary.org/obo/CL_4023042) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex `http://purl.obolibrary.org/obo/CL_4023050` + +#### Added +- [L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex](http://purl.obolibrary.org/obo/CL_4023050) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### L6b glutamatergic cortical neuron `http://purl.obolibrary.org/obo/CL_4023038` + +#### Added +- [L6b glutamatergic cortical neuron](http://purl.obolibrary.org/obo/CL_4023038) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### LATIN `http://purl.obolibrary.org/obo/uberon/core#LATIN` +#### Removed +- AnnotationProperty: [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) SubPropertyOf: [synonym_type_property](http://www.geneontology.org/formats/oboInOwl#SynonymTypeProperty) + + + +### Langerhans cell `http://purl.obolibrary.org/obo/CL_0000453` + +#### Added +- [Langerhans cell](http://purl.obolibrary.org/obo/CL_0000453) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### Leydig cell `http://purl.obolibrary.org/obo/CL_0000178` + +#### Added +- [Leydig cell](http://purl.obolibrary.org/obo/CL_0000178) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### M cell of gut `http://purl.obolibrary.org/obo/CL_0000682` + +#### Added +- [M cell of gut](http://purl.obolibrary.org/obo/CL_0000682) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### MHC-II-positive classical monocyte `http://purl.obolibrary.org/obo/CL_0002470` + +#### Added +- [MHC-II-positive classical monocyte](http://purl.obolibrary.org/obo/CL_0002470) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### Malpighian tubule `http://purl.obolibrary.org/obo/UBERON_0001054` +#### Removed +- [Malpighian tubule](http://purl.obolibrary.org/obo/UBERON_0001054) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005786" + +#### Added +- [Malpighian tubule](http://purl.obolibrary.org/obo/UBERON_0001054) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005786" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### Merkel cell `http://purl.obolibrary.org/obo/CL_0000242` + +#### Added +- [Merkel cell](http://purl.obolibrary.org/obo/CL_0000242) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### Mueller cell `http://purl.obolibrary.org/obo/CL_0000636` + +#### Added +- [Mueller cell](http://purl.obolibrary.org/obo/CL_0000636) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### NKp44-negative group 3 innate lymphoid cell, human `http://purl.obolibrary.org/obo/CL_0001080` + +#### Added +- [NKp44-negative group 3 innate lymphoid cell, human](http://purl.obolibrary.org/obo/CL_0001080) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### NKp44-positive group 3 innate lymphoid cell, human `http://purl.obolibrary.org/obo/CL_0001079` + +#### Added +- [NKp44-positive group 3 innate lymphoid cell, human](http://purl.obolibrary.org/obo/CL_0001079) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### NKp46-positive innate lymphoid cell, human `http://purl.obolibrary.org/obo/CL_0001076` + +#### Added +- [NKp46-positive innate lymphoid cell, human](http://purl.obolibrary.org/obo/CL_0001076) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### OFF retinal ganglion cell `http://purl.obolibrary.org/obo/CL_4023033` + +#### Added +- [OFF retinal ganglion cell](http://purl.obolibrary.org/obo/CL_4023033) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### OFF-bipolar cell `http://purl.obolibrary.org/obo/CL_0000750` + +#### Added +- [OFF-bipolar cell](http://purl.obolibrary.org/obo/CL_0000750) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### OMO_0003002 `http://purl.obolibrary.org/obo/OMO_0003002` + +#### Added +- AnnotationProperty: [OMO_0003002](http://purl.obolibrary.org/obo/OMO_0003002) + +- [OMO_0003002](http://purl.obolibrary.org/obo/OMO_0003002) SubPropertyOf: [synonym_type_property](http://www.geneontology.org/formats/oboInOwl#SynonymTypeProperty) + + +### OMO_0003011 `http://purl.obolibrary.org/obo/OMO_0003011` + +#### Added +- AnnotationProperty: [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) SubPropertyOf: [synonym_type_property](http://www.geneontology.org/formats/oboInOwl#SynonymTypeProperty) + + +### ON retinal ganglion cell `http://purl.obolibrary.org/obo/CL_4023032` + +#### Added +- [ON retinal ganglion cell](http://purl.obolibrary.org/obo/CL_4023032) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### ON-bipolar cell `http://purl.obolibrary.org/obo/CL_0000749` + +#### Added +- [ON-bipolar cell](http://purl.obolibrary.org/obo/CL_0000749) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### P/D1 enteroendocrine cell `http://purl.obolibrary.org/obo/CL_0002268` + +#### Added +- [P/D1 enteroendocrine cell](http://purl.obolibrary.org/obo/CL_0002268) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### PP cell `http://purl.obolibrary.org/obo/CL_0000696` + +#### Added +- [PP cell](http://purl.obolibrary.org/obo/CL_0000696) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### Peyer's patch `http://purl.obolibrary.org/obo/UBERON_0001211` +#### Removed +- [Peyer's patch](http://purl.obolibrary.org/obo/UBERON_0001211) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "noduli lymphoidei aggregati" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [Peyer's patch](http://purl.obolibrary.org/obo/UBERON_0001211) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "noduli lymphoidei aggregati" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### Purkinje cell `http://purl.obolibrary.org/obo/CL_0000121` + +#### Added +- [Purkinje cell](http://purl.obolibrary.org/obo/CL_0000121) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### Purkinje cell layer of cerebellar cortex `http://purl.obolibrary.org/obo/UBERON_0002979` +#### Removed +- [Purkinje cell layer of cerebellar cortex](http://purl.obolibrary.org/obo/UBERON_0002979) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus thalamicus reticularis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:365" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [Purkinje cell layer of cerebellar cortex](http://purl.obolibrary.org/obo/UBERON_0002979) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus reticularis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:365" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [Purkinje cell layer of cerebellar cortex](http://purl.obolibrary.org/obo/UBERON_0002979) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "reticulatum thalami (Hassler)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:365" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [Purkinje cell layer of cerebellar cortex](http://purl.obolibrary.org/obo/UBERON_0002979) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nuclei reticulares (thalami)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:365" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [Purkinje cell layer of cerebellar cortex](http://purl.obolibrary.org/obo/UBERON_0002979) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus reticulatus (thalami)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:365" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [Purkinje cell layer of cerebellar cortex](http://purl.obolibrary.org/obo/UBERON_0002979) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus thalamicus reticularis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:365" + +- [Purkinje cell layer of cerebellar cortex](http://purl.obolibrary.org/obo/UBERON_0002979) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus reticularis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:365" + +- [Purkinje cell layer of cerebellar cortex](http://purl.obolibrary.org/obo/UBERON_0002979) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nuclei reticulares (thalami)" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:365" + +- [Purkinje cell layer of cerebellar cortex](http://purl.obolibrary.org/obo/UBERON_0002979) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus reticulatus (thalami)" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:365" + +- [Purkinje cell layer of cerebellar cortex](http://purl.obolibrary.org/obo/UBERON_0002979) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "reticulatum thalami (Hassler)" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:365" + + +### RNA binding `http://purl.obolibrary.org/obo/GO_0003723` +#### Removed +- [RNA binding](http://purl.obolibrary.org/obo/GO_0003723) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [prokaryote_subset](http://purl.obolibrary.org/obo/go#prokaryote_subset) + +#### Added +- [RNA binding](http://purl.obolibrary.org/obo/GO_0003723) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_prokaryote](http://purl.obolibrary.org/obo/go#goslim_prokaryote) + + +### RNA metabolic process `http://purl.obolibrary.org/obo/GO_0016070` +#### Removed +- [RNA metabolic process](http://purl.obolibrary.org/obo/GO_0016070) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [prokaryote_subset](http://purl.obolibrary.org/obo/go#prokaryote_subset) + +#### Added +- [RNA metabolic process](http://purl.obolibrary.org/obo/GO_0016070) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_prokaryote](http://purl.obolibrary.org/obo/go#goslim_prokaryote) + + +### S cone cell `http://purl.obolibrary.org/obo/CL_0003050` + +#### Added +- [S cone cell](http://purl.obolibrary.org/obo/CL_0003050) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### S-shaped body `http://purl.obolibrary.org/obo/UBERON_0004199` + +#### Added +- [S-shaped body](http://purl.obolibrary.org/obo/UBERON_0004199) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "VO:0010896" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + - [author_id](https://w3id.org/sssom/author_id) [0000-0003-4423-4370](https://orcid.org/0000-0003-4423-4370) + + +### Schwann cell `http://purl.obolibrary.org/obo/CL_0002573` + +#### Added +- [Schwann cell](http://purl.obolibrary.org/obo/CL_0002573) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### Schwann cell precursor `http://purl.obolibrary.org/obo/CL_0002375` + +#### Added +- [Schwann cell precursor](http://purl.obolibrary.org/obo/CL_0002375) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### Sertoli cell `http://purl.obolibrary.org/obo/CL_0000216` + +#### Added +- [Sertoli cell](http://purl.obolibrary.org/obo/CL_0000216) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### T cell `http://purl.obolibrary.org/obo/CL_0000084` + +#### Added +- [T cell](http://purl.obolibrary.org/obo/CL_0000084) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### T follicular helper cell `http://purl.obolibrary.org/obo/CL_0002038` + +#### Added +- [T follicular helper cell](http://purl.obolibrary.org/obo/CL_0002038) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### T follicular regulatory cell `http://purl.obolibrary.org/obo/CL_0009113` + +#### Added +- [T follicular regulatory cell](http://purl.obolibrary.org/obo/CL_0009113) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### T-helper 1 cell `http://purl.obolibrary.org/obo/CL_0000545` + +#### Added +- [T-helper 1 cell](http://purl.obolibrary.org/obo/CL_0000545) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### T-helper 17 cell `http://purl.obolibrary.org/obo/CL_0000899` + +#### Added +- [T-helper 17 cell](http://purl.obolibrary.org/obo/CL_0000899) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### T-helper 2 cell `http://purl.obolibrary.org/obo/CL_0000546` + +#### Added +- [T-helper 2 cell](http://purl.obolibrary.org/obo/CL_0000546) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### T-helper 22 cell `http://purl.obolibrary.org/obo/CL_0001042` + +#### Added +- [T-helper 22 cell](http://purl.obolibrary.org/obo/CL_0001042) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### abdominal aorta `http://purl.obolibrary.org/obo/UBERON_0001516` +#### Removed +- [abdominal aorta](http://purl.obolibrary.org/obo/UBERON_0001516) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "pars abdominalis aortae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Abdominal_aorta" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0002976" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [abdominal aorta](http://purl.obolibrary.org/obo/UBERON_0001516) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "aorta abdominalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Abdominal_aorta" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0002976" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [abdominal aorta](http://purl.obolibrary.org/obo/UBERON_0001516) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "aorta abdominalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Abdominal_aorta" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0002976" + +- [abdominal aorta](http://purl.obolibrary.org/obo/UBERON_0001516) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "pars abdominalis aortae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Abdominal_aorta" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0002976" + + +### abdominal cavity `http://purl.obolibrary.org/obo/UBERON_0003684` +#### Removed +- [abdominal cavity](http://purl.obolibrary.org/obo/UBERON_0003684) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cavitas abdominis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GAID:17" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Abdominal_cavity" + +#### Added +- [abdominal cavity](http://purl.obolibrary.org/obo/UBERON_0003684) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cavitas abdominis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GAID:17" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Abdominal_cavity" + + +### abdominal wall `http://purl.obolibrary.org/obo/UBERON_0003697` +#### Removed +- [abdominal wall](http://purl.obolibrary.org/obo/UBERON_0003697) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "paries abdominalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Abdominal_wall" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [abdominal wall](http://purl.obolibrary.org/obo/UBERON_0003697) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "paries abdominalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Abdominal_wall" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### abdominopelvic cavity `http://purl.obolibrary.org/obo/UBERON_0035819` +#### Removed +- [abdominopelvic cavity](http://purl.obolibrary.org/obo/UBERON_0035819) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cavitas abdominis et pelvis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [abdominopelvic cavity](http://purl.obolibrary.org/obo/UBERON_0035819) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cavitas abdominis et pelvis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### abnormal cell `http://purl.obolibrary.org/obo/CL_0001061` + +#### Added +- [abnormal cell](http://purl.obolibrary.org/obo/CL_0001061) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### accessory XI nerve `http://purl.obolibrary.org/obo/UBERON_0002019` +#### Removed +- [accessory XI nerve](http://purl.obolibrary.org/obo/UBERON_0002019) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nervus accessorius [XI]" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:6720" + +- [accessory XI nerve](http://purl.obolibrary.org/obo/UBERON_0002019) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pars spinalis nervus accessorius" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:6720" + +- [accessory XI nerve](http://purl.obolibrary.org/obo/UBERON_0002019) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "radix spinalis nervus accessorius" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:6720" + +#### Added +- [accessory XI nerve](http://purl.obolibrary.org/obo/UBERON_0002019) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pars spinalis nervus accessorius" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:6720" + +- [accessory XI nerve](http://purl.obolibrary.org/obo/UBERON_0002019) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "radix spinalis nervus accessorius" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:6720" + +- [accessory XI nerve](http://purl.obolibrary.org/obo/UBERON_0002019) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nervus accessorius [XI]" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:6720" + + +### accessory XI nerve nucleus `http://purl.obolibrary.org/obo/UBERON_0020358` +#### Removed +- [accessory XI nerve nucleus](http://purl.obolibrary.org/obo/UBERON_0020358) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus nervi accessorii" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:2003" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [accessory XI nerve nucleus](http://purl.obolibrary.org/obo/UBERON_0020358) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus accessorius columnae anterioris medullae spinalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:2003" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [accessory XI nerve nucleus](http://purl.obolibrary.org/obo/UBERON_0020358) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus nervi accessorii" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:2003" + +- [accessory XI nerve nucleus](http://purl.obolibrary.org/obo/UBERON_0020358) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus accessorius columnae anterioris medullae spinalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:2003" + + +### accessory nerve root `http://purl.obolibrary.org/obo/UBERON_0014615` +#### Removed +- [accessory nerve root](http://purl.obolibrary.org/obo/UBERON_0014615) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "pars vagalis of nervus accessorius" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:703" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [accessory nerve root](http://purl.obolibrary.org/obo/UBERON_0014615) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "radices craniales nervi accessorii" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:703" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [accessory nerve root](http://purl.obolibrary.org/obo/UBERON_0014615) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "pars vagalis of nervus accessorius" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:703" + +- [accessory nerve root](http://purl.obolibrary.org/obo/UBERON_0014615) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "radices craniales nervi accessorii" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:703" + + +### acellular anatomical structure `http://purl.obolibrary.org/obo/UBERON_0000476` +#### Removed +- [acellular anatomical structure](http://purl.obolibrary.org/obo/UBERON_0000476) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007013" + +#### Added +- [acellular anatomical structure](http://purl.obolibrary.org/obo/UBERON_0000476) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007013" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### acinar cell `http://purl.obolibrary.org/obo/CL_0000622` + +#### Added +- [acinar cell](http://purl.obolibrary.org/obo/CL_0000622) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### acinar cell of salivary gland `http://purl.obolibrary.org/obo/CL_0002623` + +#### Added +- [acinar cell of salivary gland](http://purl.obolibrary.org/obo/CL_0002623) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### acromioclavicular joint `http://purl.obolibrary.org/obo/UBERON_0003692` +#### Removed +- [acromioclavicular joint](http://purl.obolibrary.org/obo/UBERON_0003692) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "articulatio acromioclavicularis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Acromioclavicular_joint" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [acromioclavicular joint](http://purl.obolibrary.org/obo/UBERON_0003692) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "articulatio acromioclavicularis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Acromioclavicular_joint" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### activated CD4-positive, alpha-beta T cell `http://purl.obolibrary.org/obo/CL_0000896` + +#### Added +- [activated CD4-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000896) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### activated CD4-positive, alpha-beta T cell, human `http://purl.obolibrary.org/obo/CL_0001043` + +#### Added +- [activated CD4-positive, alpha-beta T cell, human](http://purl.obolibrary.org/obo/CL_0001043) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### activated CD8-positive, alpha-beta T cell `http://purl.obolibrary.org/obo/CL_0000906` + +#### Added +- [activated CD8-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000906) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### activated CD8-positive, alpha-beta T cell, human `http://purl.obolibrary.org/obo/CL_0001049` + +#### Added +- [activated CD8-positive, alpha-beta T cell, human](http://purl.obolibrary.org/obo/CL_0001049) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### activated type II NK T cell `http://purl.obolibrary.org/obo/CL_0000931` + +#### Added +- [activated type II NK T cell](http://purl.obolibrary.org/obo/CL_0000931) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### adenohypophysis `http://purl.obolibrary.org/obo/UBERON_0002196` +#### Removed +- [adenohypophysis](http://purl.obolibrary.org/obo/UBERON_0002196) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lobus anterior hypophysis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:74627" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [adenohypophysis](http://purl.obolibrary.org/obo/UBERON_0002196) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lobus anterior (glandula pituitaria)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:74627" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [adenohypophysis](http://purl.obolibrary.org/obo/UBERON_0002196) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "lobus anterior" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:407" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [adenohypophysis](http://purl.obolibrary.org/obo/UBERON_0002196) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lobus anterior hypophysis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:74627" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [adenohypophysis](http://purl.obolibrary.org/obo/UBERON_0002196) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "lobus anterior" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:407" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [adenohypophysis](http://purl.obolibrary.org/obo/UBERON_0002196) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lobus anterior (glandula pituitaria)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:74627" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### adipocyte `http://purl.obolibrary.org/obo/CL_0000136` + +#### Added +- [adipocyte](http://purl.obolibrary.org/obo/CL_0000136) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### adipocyte of breast `http://purl.obolibrary.org/obo/CL_0002617` + +#### Added +- [adipocyte of breast](http://purl.obolibrary.org/obo/CL_0002617) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### adipocyte of epicardial fat of left ventricle `http://purl.obolibrary.org/obo/CL_1000311` + +#### Added +- [adipocyte of epicardial fat of left ventricle](http://purl.obolibrary.org/obo/CL_1000311) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### adrenal cortex `http://purl.obolibrary.org/obo/UBERON_0001235` +#### Removed +- [adrenal cortex](http://purl.obolibrary.org/obo/UBERON_0001235) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cortex glandulae suprarenalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0000045" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Adrenal_cortex" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [adrenal cortex](http://purl.obolibrary.org/obo/UBERON_0001235) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cortex glandulae suprarenalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0000045" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Adrenal_cortex" + + +### adrenal gland `http://purl.obolibrary.org/obo/UBERON_0002369` +#### Removed +- [adrenal gland](http://purl.obolibrary.org/obo/UBERON_0002369) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "glandula suprarenalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Adrenal_gland" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [adrenal gland](http://purl.obolibrary.org/obo/UBERON_0002369) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "glandula adrenalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Adrenal_gland" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [adrenal gland](http://purl.obolibrary.org/obo/UBERON_0002369) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "glandula adrenalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Adrenal_gland" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [adrenal gland](http://purl.obolibrary.org/obo/UBERON_0002369) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "glandula suprarenalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Adrenal_gland" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### adrenal medulla `http://purl.obolibrary.org/obo/UBERON_0001236` +#### Removed +- [adrenal medulla](http://purl.obolibrary.org/obo/UBERON_0001236) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "medulla glandulae suprarenalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:15633" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [adrenal medulla](http://purl.obolibrary.org/obo/UBERON_0001236) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "medulla glandulae suprarenalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:15633" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### adult organism `http://purl.obolibrary.org/obo/UBERON_0007023` +#### Removed +- [adult organism](http://purl.obolibrary.org/obo/UBERON_0007023) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00003004" + +#### Added +- [adult organism](http://purl.obolibrary.org/obo/UBERON_0007023) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00003004" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### adventitia `http://purl.obolibrary.org/obo/UBERON_0005742` +#### Removed +- [adventitia](http://purl.obolibrary.org/obo/UBERON_0005742) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D063194" + +#### Added +- [adventitia](http://purl.obolibrary.org/obo/UBERON_0005742) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D063194" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [author_id](https://w3id.org/sssom/author_id) [0000-0001-9439-5346](https://orcid.org/0000-0001-9439-5346) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### adventitia of ductus deferens `http://purl.obolibrary.org/obo/UBERON_0006647` +#### Removed +- [adventitia of ductus deferens](http://purl.obolibrary.org/obo/UBERON_0006647) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica adventitia ductus deferentis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:19238" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [adventitia of ductus deferens](http://purl.obolibrary.org/obo/UBERON_0006647) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica adventitia ductus deferentis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:19238" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### adventitia of seminal vesicle `http://purl.obolibrary.org/obo/UBERON_0006648` +#### Removed +- [adventitia of seminal vesicle](http://purl.obolibrary.org/obo/UBERON_0006648) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica adventitia glandulae vesiculosae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:19403" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [adventitia of seminal vesicle](http://purl.obolibrary.org/obo/UBERON_0006648) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica adventitia glandulae vesiculosae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:19403" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### adventitia of ureter `http://purl.obolibrary.org/obo/UBERON_0001252` +#### Removed +- [adventitia of ureter](http://purl.obolibrary.org/obo/UBERON_0001252) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica adventitia ureteris" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:15892" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [adventitia of ureter](http://purl.obolibrary.org/obo/UBERON_0001252) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica adventitia (ureter)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:15892" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [adventitia of ureter](http://purl.obolibrary.org/obo/UBERON_0001252) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica adventitia (ureter)" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:15892" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [adventitia of ureter](http://purl.obolibrary.org/obo/UBERON_0001252) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica adventitia ureteris" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:15892" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### adventitial cell `http://purl.obolibrary.org/obo/CL_0002503` + +#### Added +- [adventitial cell](http://purl.obolibrary.org/obo/CL_0002503) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### alpha-amino acid biosynthetic process `http://purl.obolibrary.org/obo/GO_1901607` +#### Removed +- [alpha-amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_1901607) SubClassOf [amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0008652) + +#### Added +- [alpha-amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_1901607) SubClassOf [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) + + +### alpha-amino acid metabolic process `http://purl.obolibrary.org/obo/GO_1901605` +#### Removed +- [alpha-amino acid metabolic process](http://purl.obolibrary.org/obo/GO_1901605) SubClassOf [amino acid metabolic process](http://purl.obolibrary.org/obo/GO_0006520) + +#### Added +- [alpha-amino acid metabolic process](http://purl.obolibrary.org/obo/GO_1901605) SubClassOf [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) + + +### alpha-beta T cell `http://purl.obolibrary.org/obo/CL_0000789` + +#### Added +- [alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000789) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### alternatively activated macrophage `http://purl.obolibrary.org/obo/CL_0000890` + +#### Added +- [alternatively activated macrophage](http://purl.obolibrary.org/obo/CL_0000890) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### alveolar macrophage `http://purl.obolibrary.org/obo/CL_0000583` + +#### Added +- [alveolar macrophage](http://purl.obolibrary.org/obo/CL_0000583) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### alveolar ridge `http://purl.obolibrary.org/obo/UBERON_0004103` +#### Removed +- [alveolar ridge](http://purl.obolibrary.org/obo/UBERON_0004103) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "margo alveolaris" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [alveolar ridge](http://purl.obolibrary.org/obo/UBERON_0004103) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "margo alveolaris" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### alveolar type 1 fibroblast cell `http://purl.obolibrary.org/obo/CL_4028004` + +#### Added +- [alveolar type 1 fibroblast cell](http://purl.obolibrary.org/obo/CL_4028004) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### alveolar type 2 fibroblast cell `http://purl.obolibrary.org/obo/CL_4028006` + +#### Added +- [alveolar type 2 fibroblast cell](http://purl.obolibrary.org/obo/CL_4028006) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### alveolus of lung `http://purl.obolibrary.org/obo/UBERON_0002299` +#### Removed +- [alveolus of lung](http://purl.obolibrary.org/obo/UBERON_0002299) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "alveolus pulmonis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Pulmonary_alveolus" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [alveolus of lung](http://purl.obolibrary.org/obo/UBERON_0002299) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "alveolus pulmonis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Pulmonary_alveolus" + + +### amacrine cell `http://purl.obolibrary.org/obo/CL_0000561` + +#### Added +- [amacrine cell](http://purl.obolibrary.org/obo/CL_0000561) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### amino acid biosynthetic process `http://purl.obolibrary.org/obo/GO_0008652` +#### Removed +- [amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0008652) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "amino acid synthesis" + +- [amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0008652) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Amino_acid_synthesis" + +- [amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0008652) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cellular amino acid biosynthetic process" + +- [amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0008652) [label](http://www.w3.org/2000/01/rdf-schema#label) "amino acid biosynthetic process" + +- [amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0008652) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) "https://github.com/geneontology/go-ontology/issues/17904"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + +- [amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0008652) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the formation of amino acids, organic acids containing one or more amino substituents." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0198506732" + +- [amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0008652) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0008652) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "amino acid anabolism" + +- [amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0008652) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0008652" + +- [amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0008652) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "amino acid biosynthesis" + +- [amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0008652) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "amino acid formation" + +- Class: [amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0008652) + +- [amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0008652) EquivalentTo [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) and ([has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [CHEBI_37022](http://purl.obolibrary.org/obo/CHEBI_37022)) + +- [amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0008652) SubClassOf [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) + +- [amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0008652) SubClassOf [has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [CHEBI_37022](http://purl.obolibrary.org/obo/CHEBI_37022) + +- [amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0008652) SubClassOf [amino acid metabolic process](http://purl.obolibrary.org/obo/GO_0006520) + + + +### amino acid catabolic process `http://purl.obolibrary.org/obo/GO_0009063` +#### Removed +- [amino acid catabolic process](http://purl.obolibrary.org/obo/GO_0009063) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) "https://github.com/geneontology/go-ontology/issues/17904"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + +- [amino acid catabolic process](http://purl.obolibrary.org/obo/GO_0009063) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cellular amino acid catabolic process" + +- [amino acid catabolic process](http://purl.obolibrary.org/obo/GO_0009063) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "amino acid degradation" + +- [amino acid catabolic process](http://purl.obolibrary.org/obo/GO_0009063) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [amino acid catabolic process](http://purl.obolibrary.org/obo/GO_0009063) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0009063" + +- [amino acid catabolic process](http://purl.obolibrary.org/obo/GO_0009063) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "amino acid breakdown" + +- [amino acid catabolic process](http://purl.obolibrary.org/obo/GO_0009063) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the breakdown of amino acids, organic acids containing one or more amino substituents." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" + +- [amino acid catabolic process](http://purl.obolibrary.org/obo/GO_0009063) [label](http://www.w3.org/2000/01/rdf-schema#label) "amino acid catabolic process" + +- [amino acid catabolic process](http://purl.obolibrary.org/obo/GO_0009063) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "amino acid catabolism" + +- Class: [amino acid catabolic process](http://purl.obolibrary.org/obo/GO_0009063) + +- [amino acid catabolic process](http://purl.obolibrary.org/obo/GO_0009063) EquivalentTo [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [CHEBI_37022](http://purl.obolibrary.org/obo/CHEBI_37022)) + +- [amino acid catabolic process](http://purl.obolibrary.org/obo/GO_0009063) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [CHEBI_37022](http://purl.obolibrary.org/obo/CHEBI_37022) + +- [amino acid catabolic process](http://purl.obolibrary.org/obo/GO_0009063) SubClassOf [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) + +- [amino acid catabolic process](http://purl.obolibrary.org/obo/GO_0009063) SubClassOf [amino acid metabolic process](http://purl.obolibrary.org/obo/GO_0006520) + + + +### amino acid metabolic process `http://purl.obolibrary.org/obo/GO_0006520` +#### Removed +- [amino acid metabolic process](http://purl.obolibrary.org/obo/GO_0006520) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [prokaryote_subset](http://purl.obolibrary.org/obo/go#prokaryote_subset) + +- [amino acid metabolic process](http://purl.obolibrary.org/obo/GO_0006520) EquivalentTo [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) and ([has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [CHEBI_37022](http://purl.obolibrary.org/obo/CHEBI_37022)) + +- [amino acid metabolic process](http://purl.obolibrary.org/obo/GO_0006520) SubClassOf [carboxylic acid metabolic process](http://purl.obolibrary.org/obo/GO_0019752) + +- [amino acid metabolic process](http://purl.obolibrary.org/obo/GO_0006520) SubClassOf [has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [CHEBI_37022](http://purl.obolibrary.org/obo/CHEBI_37022) + +- [amino acid metabolic process](http://purl.obolibrary.org/obo/GO_0006520) SubClassOf [organonitrogen compound metabolic process](http://purl.obolibrary.org/obo/GO_1901564) + +#### Added +- [amino acid metabolic process](http://purl.obolibrary.org/obo/GO_0006520) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_prokaryote](http://purl.obolibrary.org/obo/go#goslim_prokaryote) + +- [amino acid metabolic process](http://purl.obolibrary.org/obo/GO_0006520) EquivalentTo [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) and ([has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [CHEBI_35238](http://purl.obolibrary.org/obo/CHEBI_35238)) + +- [amino acid metabolic process](http://purl.obolibrary.org/obo/GO_0006520) SubClassOf [has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [CHEBI_35238](http://purl.obolibrary.org/obo/CHEBI_35238) + + +### amnioserosa `http://purl.obolibrary.org/obo/UBERON_0010302` +#### Removed +- [amnioserosa](http://purl.obolibrary.org/obo/UBERON_0010302) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00000095" + +#### Added +- [amnioserosa](http://purl.obolibrary.org/obo/UBERON_0010302) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00000095" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### amniotic fluid `http://purl.obolibrary.org/obo/UBERON_0000173` +#### Removed +- [amniotic fluid](http://purl.obolibrary.org/obo/UBERON_0000173) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "acqua amnii" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0000068" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [amniotic fluid](http://purl.obolibrary.org/obo/UBERON_0000173) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "liquor amnii" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0000068" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [amniotic fluid](http://purl.obolibrary.org/obo/UBERON_0000173) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "acqua amnii" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0000068" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [amniotic fluid](http://purl.obolibrary.org/obo/UBERON_0000173) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "liquor amnii" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0000068" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### amygdala `http://purl.obolibrary.org/obo/UBERON_0001876` +#### Removed +- [amygdala](http://purl.obolibrary.org/obo/UBERON_0001876) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "corpus amygdaloideum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0001042" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Amygdala" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [amygdala](http://purl.obolibrary.org/obo/UBERON_0001876) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "corpus amygdalae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:237" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [amygdala](http://purl.obolibrary.org/obo/UBERON_0001876) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "corpus amygdalae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:237" + +- [amygdala](http://purl.obolibrary.org/obo/UBERON_0001876) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "corpus amygdaloideum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0001042" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Amygdala" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### anal canal `http://purl.obolibrary.org/obo/UBERON_0000159` +#### Removed +- [anal canal](http://purl.obolibrary.org/obo/UBERON_0000159) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D001003" + +- [anal canal](http://purl.obolibrary.org/obo/UBERON_0000159) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "canalis analis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Anal_canal" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0001978" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [anal canal](http://purl.obolibrary.org/obo/UBERON_0000159) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "canalis analis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Anal_canal" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0001978" + +- [anal canal](http://purl.obolibrary.org/obo/UBERON_0000159) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D001003" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [author_id](https://w3id.org/sssom/author_id) [0000-0001-9439-5346](https://orcid.org/0000-0001-9439-5346) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### anal column `http://purl.obolibrary.org/obo/UBERON_0009882` +#### Removed +- [anal column](http://purl.obolibrary.org/obo/UBERON_0009882) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "columnae anales" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Anal_columns" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [anal column](http://purl.obolibrary.org/obo/UBERON_0009882) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "columnae anales" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Anal_columns" + + +### anatomical cluster `http://purl.obolibrary.org/obo/UBERON_0000477` +#### Removed +- [anatomical cluster](http://purl.obolibrary.org/obo/UBERON_0000477) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IDOMAL:0002461" + - [contributor](http://purl.org/dc/terms/contributor) "https://orcid.org/0000-0003-4423-4370" + +- [anatomical cluster](http://purl.obolibrary.org/obo/UBERON_0000477) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007277" + +#### Added +- [anatomical cluster](http://purl.obolibrary.org/obo/UBERON_0000477) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007277" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### anatomical entity `http://purl.obolibrary.org/obo/UBERON_0001062` +#### Removed +- [anatomical entity](http://purl.obolibrary.org/obo/UBERON_0001062) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:10000000" + +#### Added +- [anatomical entity](http://purl.obolibrary.org/obo/UBERON_0001062) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:10000000" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### anatomical lobe `http://purl.obolibrary.org/obo/UBERON_0009912` +#### Removed +- [anatomical lobe](http://purl.obolibrary.org/obo/UBERON_0009912) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lobus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:45728" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [anatomical lobe](http://purl.obolibrary.org/obo/UBERON_0009912) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lobus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:45728" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### anatomical projection `http://purl.obolibrary.org/obo/UBERON_0004529` +#### Removed +- [anatomical projection](http://purl.obolibrary.org/obo/UBERON_0004529) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "processus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:67601" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [anatomical projection](http://purl.obolibrary.org/obo/UBERON_0004529) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "processus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:67601" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### anatomical row `http://purl.obolibrary.org/obo/UBERON_0034926` +#### Removed +- [anatomical row](http://purl.obolibrary.org/obo/UBERON_0034926) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00100152" + +#### Added +- [anatomical row](http://purl.obolibrary.org/obo/UBERON_0034926) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00100152" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### anatomical space `http://purl.obolibrary.org/obo/UBERON_0000464` +#### Removed +- [anatomical space](http://purl.obolibrary.org/obo/UBERON_0000464) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007017" + +#### Added +- [anatomical space](http://purl.obolibrary.org/obo/UBERON_0000464) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007017" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### anatomical structure `http://purl.obolibrary.org/obo/UBERON_0000061` +#### Removed +- [anatomical structure](http://purl.obolibrary.org/obo/UBERON_0000061) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007001" + +#### Added +- [anatomical structure](http://purl.obolibrary.org/obo/UBERON_0000061) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007001" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### anatomical structure development `http://purl.obolibrary.org/obo/GO_0048856` + +#### Added +- [anatomical structure development](http://purl.obolibrary.org/obo/GO_0048856) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) "https://github.com/geneontology/go-ontology/issues/26424"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + +- [anatomical structure development](http://purl.obolibrary.org/obo/GO_0048856) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [gocheck_do_not_annotate](http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate) + + +### anatomical system `http://purl.obolibrary.org/obo/UBERON_0000467` +#### Removed +- [anatomical system](http://purl.obolibrary.org/obo/UBERON_0000467) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IDOMAL:0002460" + - [contributor](http://purl.org/dc/terms/contributor) "https://orcid.org/0000-0003-4423-4370" + +- [anatomical system](http://purl.obolibrary.org/obo/UBERON_0000467) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00004856" + +#### Added +- [anatomical system](http://purl.obolibrary.org/obo/UBERON_0000467) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IDOMAL:0002460" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + - [author_id](https://w3id.org/sssom/author_id) [0000-0003-4423-4370](https://orcid.org/0000-0003-4423-4370) + +- [anatomical system](http://purl.obolibrary.org/obo/UBERON_0000467) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00004856" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### anlage `http://purl.obolibrary.org/obo/UBERON_0007688` +#### Removed +- [anlage](http://purl.obolibrary.org/obo/UBERON_0007688) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005426" + +#### Added +- [anlage](http://purl.obolibrary.org/obo/UBERON_0007688) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005426" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### annulus fibrosus `http://purl.obolibrary.org/obo/UBERON_0006444` +#### Removed +- [annulus fibrosus](http://purl.obolibrary.org/obo/UBERON_0006444) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D000070616" + +#### Added +- [annulus fibrosus](http://purl.obolibrary.org/obo/UBERON_0006444) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D000070616" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [author_id](https://w3id.org/sssom/author_id) [0000-0001-9439-5346](https://orcid.org/0000-0001-9439-5346) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### anterior chamber of eyeball `http://purl.obolibrary.org/obo/UBERON_0001766` +#### Removed +- [anterior chamber of eyeball](http://purl.obolibrary.org/obo/UBERON_0001766) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "camera anterior bulbi oculi" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Anterior_chamber_of_eyeball" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [anterior chamber of eyeball](http://purl.obolibrary.org/obo/UBERON_0001766) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "camera anterior bulbi oculi" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Anterior_chamber_of_eyeball" + + +### anterior lens cell `http://purl.obolibrary.org/obo/CL_0002223` + +#### Added +- [anterior lens cell](http://purl.obolibrary.org/obo/CL_0002223) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### anterior limiting lamina of cornea `http://purl.obolibrary.org/obo/UBERON_0004370` +#### Removed +- [anterior limiting lamina of cornea](http://purl.obolibrary.org/obo/UBERON_0004370) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lamina limitans anterior corneae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:58273" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [anterior limiting lamina of cornea](http://purl.obolibrary.org/obo/UBERON_0004370) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Reichert's membrane" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [DUBIOUS](http://purl.obolibrary.org/obo/uberon/core#DUBIOUS) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "http://sourceforge.net/tracker/?func=detail&aid=2956371&group_id=76834&atid=974957" + +#### Added +- [anterior limiting lamina of cornea](http://purl.obolibrary.org/obo/UBERON_0004370) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lamina limitans anterior corneae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:58273" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [anterior limiting lamina of cornea](http://purl.obolibrary.org/obo/UBERON_0004370) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Reichert's membrane" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003002](http://purl.obolibrary.org/obo/OMO_0003002) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "http://sourceforge.net/tracker/?func=detail&aid=2956371&group_id=76834&atid=974957" + + +### anterior part of tongue `http://purl.obolibrary.org/obo/UBERON_0010032` +#### Removed +- [anterior part of tongue](http://purl.obolibrary.org/obo/UBERON_0010032) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "pars anterior dorsi linguae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Anterior_tongue" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [anterior part of tongue](http://purl.obolibrary.org/obo/UBERON_0010032) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "pars anterior dorsi linguae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Anterior_tongue" + + +### anterior segment of eyeball `http://purl.obolibrary.org/obo/UBERON_0001801` +#### Removed +- [anterior segment of eyeball](http://purl.obolibrary.org/obo/UBERON_0001801) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "segmentum anterius bulbi oculi" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Anterior_segment_of_eyeball" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [anterior segment of eyeball](http://purl.obolibrary.org/obo/UBERON_0001801) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "segmentum anterius bulbi oculi" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Anterior_segment_of_eyeball" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### anterior surface of prostate `http://purl.obolibrary.org/obo/UBERON_0035523` +#### Removed +- [anterior surface of prostate](http://purl.obolibrary.org/obo/UBERON_0035523) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "facies anterior prostatae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:19591" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [anterior surface of prostate](http://purl.obolibrary.org/obo/UBERON_0035523) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "facies anterior prostatae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:19591" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### anterior tibial vein `http://purl.obolibrary.org/obo/UBERON_0001545` +#### Removed +- [anterior tibial vein](http://purl.obolibrary.org/obo/UBERON_0001545) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "venae tibiales anteriores" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Anterior_tibial_vein" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [anterior tibial vein](http://purl.obolibrary.org/obo/UBERON_0001545) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "venae tibiales anteriores" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Anterior_tibial_vein" + + +### anterior vena cava `http://purl.obolibrary.org/obo/UBERON_0001585` +#### Removed +- [anterior vena cava](http://purl.obolibrary.org/obo/UBERON_0001585) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vena cava superior" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Superior_vena_cava" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0002683" + +- [anterior vena cava](http://purl.obolibrary.org/obo/UBERON_0001585) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vena maxima" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Superior_vena_cava" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [anterior vena cava](http://purl.obolibrary.org/obo/UBERON_0001585) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vena cava superior" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Superior_vena_cava" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0002683" + +- [anterior vena cava](http://purl.obolibrary.org/obo/UBERON_0001585) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vena maxima" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Superior_vena_cava" + + +### anterograde trans-synaptic signaling by nitric oxide `http://purl.obolibrary.org/obo/GO_0098940` +#### Removed +- [anterograde trans-synaptic signaling by nitric oxide](http://purl.obolibrary.org/obo/GO_0098940) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_synapse](http://purl.obolibrary.org/obo/go#goslim_synapse) + +- [anterograde trans-synaptic signaling by nitric oxide](http://purl.obolibrary.org/obo/GO_0098940) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Cell-cell signaling from presynapse to postynapse, across the synaptic cleft, mediated by nitric oxide." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:dos" + +- [anterograde trans-synaptic signaling by nitric oxide](http://purl.obolibrary.org/obo/GO_0098940) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0098940" + +- [anterograde trans-synaptic signaling by nitric oxide](http://purl.obolibrary.org/obo/GO_0098940) [label](http://www.w3.org/2000/01/rdf-schema#label) "anterograde trans-synaptic signaling by nitric oxide" + +- [anterograde trans-synaptic signaling by nitric oxide](http://purl.obolibrary.org/obo/GO_0098940) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- Class: [anterograde trans-synaptic signaling by nitric oxide](http://purl.obolibrary.org/obo/GO_0098940) + +- [anterograde trans-synaptic signaling by nitric oxide](http://purl.obolibrary.org/obo/GO_0098940) EquivalentTo [trans-synaptic signaling](http://purl.obolibrary.org/obo/GO_0099537) and ([has start location](http://purl.obolibrary.org/obo/RO_0002231) some [presynapse](http://purl.obolibrary.org/obo/GO_0098793)) and ([has end location](http://purl.obolibrary.org/obo/RO_0002232) some [postsynapse](http://purl.obolibrary.org/obo/GO_0098794)) and ([process has causal agent](http://purl.obolibrary.org/obo/RO_0002608) some [CHEBI_16480](http://purl.obolibrary.org/obo/CHEBI_16480)) + +- [anterograde trans-synaptic signaling by nitric oxide](http://purl.obolibrary.org/obo/GO_0098940) SubClassOf [anterograde trans-synaptic signaling](http://purl.obolibrary.org/obo/GO_0098916) + +- [anterograde trans-synaptic signaling by nitric oxide](http://purl.obolibrary.org/obo/GO_0098940) SubClassOf [trans-synaptic signaling by nitric oxide](http://purl.obolibrary.org/obo/GO_0099548) + + + +### anteroventral cochlear nucleus `http://purl.obolibrary.org/obo/UBERON_0002830` +#### Removed +- [anteroventral cochlear nucleus](http://purl.obolibrary.org/obo/UBERON_0002830) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus cochlearis anteroventralis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:723" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [anteroventral cochlear nucleus](http://purl.obolibrary.org/obo/UBERON_0002830) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus cochlearis anteroventralis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:723" + + +### anteroventral periventricular nucleus `http://purl.obolibrary.org/obo/UBERON_0002690` +#### Removed +- [anteroventral periventricular nucleus](http://purl.obolibrary.org/obo/UBERON_0002690) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus periventricularis anteroventralis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:382" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [anteroventral periventricular nucleus](http://purl.obolibrary.org/obo/UBERON_0002690) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus periventricularis anteroventralis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:382" + + +### antimicrobial humoral response `http://purl.obolibrary.org/obo/GO_0019730` +#### Removed +- [antimicrobial humoral response](http://purl.obolibrary.org/obo/GO_0019730) SubClassOf [defense response to other organism](http://purl.obolibrary.org/obo/GO_0098542) + +#### Added +- [antimicrobial humoral response](http://purl.obolibrary.org/obo/GO_0019730) SubClassOf [defense response to symbiont](http://purl.obolibrary.org/obo/GO_0140546) + + +### anus `http://purl.obolibrary.org/obo/UBERON_0001245` +#### Removed +- [anus](http://purl.obolibrary.org/obo/UBERON_0001245) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00047153" + +#### Added +- [anus](http://purl.obolibrary.org/obo/UBERON_0001245) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00047153" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### aorta `http://purl.obolibrary.org/obo/UBERON_0000947` +#### Removed +- [aorta](http://purl.obolibrary.org/obo/UBERON_0000947) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria maxima" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Aorta" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [aorta](http://purl.obolibrary.org/obo/UBERON_0000947) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria maxima" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Aorta" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### aortic endothelial cell `http://purl.obolibrary.org/obo/CL_0002544` + +#### Added +- [aortic endothelial cell](http://purl.obolibrary.org/obo/CL_0002544) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### aortic sac `http://purl.obolibrary.org/obo/UBERON_0005432` +#### Removed +- [aortic sac](http://purl.obolibrary.org/obo/UBERON_0005432) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "saccus aorticus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [aortic sac](http://purl.obolibrary.org/obo/UBERON_0005432) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "saccus aorticus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### aortic smooth muscle cell `http://purl.obolibrary.org/obo/CL_0002539` + +#### Added +- [aortic smooth muscle cell](http://purl.obolibrary.org/obo/CL_0002539) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### aortico-pulmonary spiral septum `http://purl.obolibrary.org/obo/UBERON_0006207` +#### Removed +- [aortico-pulmonary spiral septum](http://purl.obolibrary.org/obo/UBERON_0006207) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "septum aorticopulmonale" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Aorticopulmonary_septum" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [aortico-pulmonary spiral septum](http://purl.obolibrary.org/obo/UBERON_0006207) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "septum aorticopulmonale" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Aorticopulmonary_septum" + + +### apical ectodermal ridge `http://purl.obolibrary.org/obo/UBERON_0004356` +#### Removed +- [apical ectodermal ridge](http://purl.obolibrary.org/obo/UBERON_0004356) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "crista ectodermalis apicalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Apical_ectodermal_ridge" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [apical ectodermal ridge](http://purl.obolibrary.org/obo/UBERON_0004356) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "crista ectodermalis apicalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Apical_ectodermal_ridge" + + +### apocrine gland `http://purl.obolibrary.org/obo/UBERON_0008974` +#### Removed +- [apocrine gland](http://purl.obolibrary.org/obo/UBERON_0008974) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D001050" + +#### Added +- [apocrine gland](http://purl.obolibrary.org/obo/UBERON_0008974) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D001050" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [author_id](https://w3id.org/sssom/author_id) [0000-0001-9439-5346](https://orcid.org/0000-0001-9439-5346) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### apocrine sweat gland `http://purl.obolibrary.org/obo/UBERON_0000382` +#### Removed +- [apocrine sweat gland](http://purl.obolibrary.org/obo/UBERON_0000382) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "glandula sudorifera apocrina" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Apocrine_sweat_gland" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [apocrine sweat gland](http://purl.obolibrary.org/obo/UBERON_0000382) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "glandula sudorifera apocrina" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Apocrine_sweat_gland" + + +### aponeurosis `http://purl.obolibrary.org/obo/UBERON_0006614` +#### Removed +- [aponeurosis](http://purl.obolibrary.org/obo/UBERON_0006614) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D000070606" + +#### Added +- [aponeurosis](http://purl.obolibrary.org/obo/UBERON_0006614) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D000070606" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [author_id](https://w3id.org/sssom/author_id) [0000-0001-9439-5346](https://orcid.org/0000-0001-9439-5346) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### appendage `http://purl.obolibrary.org/obo/UBERON_0000026` +#### Removed +- [appendage](http://purl.obolibrary.org/obo/UBERON_0000026) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007000" + +#### Added +- [appendage](http://purl.obolibrary.org/obo/UBERON_0000026) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007000" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### appendicular skeleton `http://purl.obolibrary.org/obo/UBERON_0002091` +#### Removed +- [appendicular skeleton](http://purl.obolibrary.org/obo/UBERON_0002091) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "skeleton appendiculare" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Appendicular_skeleton" + +#### Added +- [appendicular skeleton](http://purl.obolibrary.org/obo/UBERON_0002091) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "skeleton appendiculare" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Appendicular_skeleton" + + +### aqueous humor of eyeball `http://purl.obolibrary.org/obo/UBERON_0001796` +#### Removed +- [aqueous humor of eyeball](http://purl.obolibrary.org/obo/UBERON_0001796) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "humor aquosus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:58819" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [aqueous humor of eyeball](http://purl.obolibrary.org/obo/UBERON_0001796) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "humor aquosus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:58819" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### arachnoid trabecula `http://purl.obolibrary.org/obo/UBERON_0000439` +#### Removed +- [arachnoid trabecula](http://purl.obolibrary.org/obo/UBERON_0000439) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "trabecula arachnoideum" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [arachnoid trabecula](http://purl.obolibrary.org/obo/UBERON_0000439) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "trabecula arachnoideum" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### arch of aorta `http://purl.obolibrary.org/obo/UBERON_0001508` +#### Removed +- [arch of aorta](http://purl.obolibrary.org/obo/UBERON_0001508) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "arcus aortae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:3768" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [arch of aorta](http://purl.obolibrary.org/obo/UBERON_0001508) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "arcus aortae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:3768" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### arcuate nucleus of hypothalamus `http://purl.obolibrary.org/obo/UBERON_0001932` +#### Removed +- [arcuate nucleus of hypothalamus](http://purl.obolibrary.org/obo/UBERON_0001932) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus arcuatus (hypothalamus)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:395" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [arcuate nucleus of hypothalamus](http://purl.obolibrary.org/obo/UBERON_0001932) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus arcuatus hypothalami" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Arcuate_nucleus" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [arcuate nucleus of hypothalamus](http://purl.obolibrary.org/obo/UBERON_0001932) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus infundibularis hypothalami" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:395" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [arcuate nucleus of hypothalamus](http://purl.obolibrary.org/obo/UBERON_0001932) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nucleus arcuatus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:62329" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [arcuate nucleus of hypothalamus](http://purl.obolibrary.org/obo/UBERON_0001932) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nucleus arcuatus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:62329" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [arcuate nucleus of hypothalamus](http://purl.obolibrary.org/obo/UBERON_0001932) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus infundibularis hypothalami" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:395" + +- [arcuate nucleus of hypothalamus](http://purl.obolibrary.org/obo/UBERON_0001932) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus arcuatus hypothalami" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Arcuate_nucleus" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [arcuate nucleus of hypothalamus](http://purl.obolibrary.org/obo/UBERON_0001932) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus arcuatus (hypothalamus)" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:395" + + +### arm `http://purl.obolibrary.org/obo/UBERON_0001460` +#### Removed +- [arm](http://purl.obolibrary.org/obo/UBERON_0001460) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "brachium" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Arm" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [arm](http://purl.obolibrary.org/obo/UBERON_0001460) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "brachium" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Arm" + + +### arm bone `http://purl.obolibrary.org/obo/UBERON_0003460` +#### Removed +- [arm bone](http://purl.obolibrary.org/obo/UBERON_0003460) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D050280" + +#### Added +- [arm bone](http://purl.obolibrary.org/obo/UBERON_0003460) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D050280" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [author_id](https://w3id.org/sssom/author_id) [0000-0001-9439-5346](https://orcid.org/0000-0001-9439-5346) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### arterial blood `http://purl.obolibrary.org/obo/UBERON_0013755` +#### Removed +- [arterial blood](http://purl.obolibrary.org/obo/UBERON_0013755) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0006188" + - [contributor](http://purl.org/dc/terms/contributor) "https://orcid.org/0000-0003-4423-4370" + +#### Added +- [arterial blood](http://purl.obolibrary.org/obo/UBERON_0013755) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0006188" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + - [author_id](https://w3id.org/sssom/author_id) [0000-0003-4423-4370](https://orcid.org/0000-0003-4423-4370) + + +### arteriole `http://purl.obolibrary.org/obo/UBERON_0001980` +#### Removed +- [arteriole](http://purl.obolibrary.org/obo/UBERON_0001980) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteriola" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Arteriole" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [arteriole](http://purl.obolibrary.org/obo/UBERON_0001980) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteriola" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Arteriole" + + +### artery of lower lip `http://purl.obolibrary.org/obo/UBERON_0003471` +#### Removed +- [artery of lower lip](http://purl.obolibrary.org/obo/UBERON_0003471) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ramus labialis inferior arteriae facialis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Inferior_labial_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [artery of lower lip](http://purl.obolibrary.org/obo/UBERON_0003471) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "arteria labialis inferior" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Inferior_labial_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [artery of lower lip](http://purl.obolibrary.org/obo/UBERON_0003471) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ramus labialis inferior arteriae facialis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Inferior_labial_artery" + +- [artery of lower lip](http://purl.obolibrary.org/obo/UBERON_0003471) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "arteria labialis inferior" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Inferior_labial_artery" + + +### artery of upper lip `http://purl.obolibrary.org/obo/UBERON_0003470` +#### Removed +- [artery of upper lip](http://purl.obolibrary.org/obo/UBERON_0003470) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "arteria labialis superior" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Superior_labial_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [artery of upper lip](http://purl.obolibrary.org/obo/UBERON_0003470) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ramus labialis superior arteriae facialis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Superior_labial_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [artery of upper lip](http://purl.obolibrary.org/obo/UBERON_0003470) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ramus labialis superior arteriae facialis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Superior_labial_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [artery of upper lip](http://purl.obolibrary.org/obo/UBERON_0003470) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "arteria labialis superior" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Superior_labial_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### arthropod sensillum `http://purl.obolibrary.org/obo/UBERON_0002536` +#### Removed +- [arthropod sensillum](http://purl.obolibrary.org/obo/UBERON_0002536) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007152" + +#### Added +- [arthropod sensillum](http://purl.obolibrary.org/obo/UBERON_0002536) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007152" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### arthropod tagma `http://purl.obolibrary.org/obo/UBERON_6000002` +#### Removed +- [arthropod tagma](http://purl.obolibrary.org/obo/UBERON_6000002) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00000002" + +#### Added +- [arthropod tagma](http://purl.obolibrary.org/obo/UBERON_6000002) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00000002" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### articular capsule `http://purl.obolibrary.org/obo/UBERON_0001484` +#### Removed +- [articular capsule](http://purl.obolibrary.org/obo/UBERON_0001484) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "capsulae articulares" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Articular_capsule" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [articular capsule](http://purl.obolibrary.org/obo/UBERON_0001484) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "capsula articularis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:34836" + +#### Added +- [articular capsule](http://purl.obolibrary.org/obo/UBERON_0001484) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "capsula articularis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:34836" + +- [articular capsule](http://purl.obolibrary.org/obo/UBERON_0001484) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "capsulae articulares" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Articular_capsule" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### articulation `http://purl.obolibrary.org/obo/UBERON_0004905` +#### Removed +- [articulation](http://purl.obolibrary.org/obo/UBERON_0004905) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005811" + +#### Added +- [articulation](http://purl.obolibrary.org/obo/UBERON_0004905) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005811" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### ascending aorta `http://purl.obolibrary.org/obo/UBERON_0001496` +#### Removed +- [ascending aorta](http://purl.obolibrary.org/obo/UBERON_0001496) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "aorta ascendens" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Ascending_aorta" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [ascending aorta](http://purl.obolibrary.org/obo/UBERON_0001496) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "pars ascendens aortae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Ascending_aorta" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [ascending aorta](http://purl.obolibrary.org/obo/UBERON_0001496) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "aorta ascendens" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Ascending_aorta" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [ascending aorta](http://purl.obolibrary.org/obo/UBERON_0001496) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "pars ascendens aortae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Ascending_aorta" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### ascending colon `http://purl.obolibrary.org/obo/UBERON_0001156` +#### Removed +- [ascending colon](http://purl.obolibrary.org/obo/UBERON_0001156) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D044682" + +- [ascending colon](http://purl.obolibrary.org/obo/UBERON_0001156) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "colon ascendens" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Ascending_colon" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [ascending colon](http://purl.obolibrary.org/obo/UBERON_0001156) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "colon ascendens" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Ascending_colon" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [ascending colon](http://purl.obolibrary.org/obo/UBERON_0001156) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D044682" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [author_id](https://w3id.org/sssom/author_id) [0000-0001-9439-5346](https://orcid.org/0000-0001-9439-5346) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### astrocyte `http://purl.obolibrary.org/obo/CL_0000127` + +#### Added +- [astrocyte](http://purl.obolibrary.org/obo/CL_0000127) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### astrocyte of the cerebellum `http://purl.obolibrary.org/obo/CL_0002603` + +#### Added +- [astrocyte of the cerebellum](http://purl.obolibrary.org/obo/CL_0002603) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### astrocyte of the cerebral cortex `http://purl.obolibrary.org/obo/CL_0002605` + +#### Added +- [astrocyte of the cerebral cortex](http://purl.obolibrary.org/obo/CL_0002605) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### atlanto-occipital joint `http://purl.obolibrary.org/obo/UBERON_0000220` +#### Removed +- [atlanto-occipital joint](http://purl.obolibrary.org/obo/UBERON_0000220) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D001269" + +- [atlanto-occipital joint](http://purl.obolibrary.org/obo/UBERON_0000220) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "articulatio atlantooccipitalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Atlanto-occipital_joint" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [atlanto-occipital joint](http://purl.obolibrary.org/obo/UBERON_0000220) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D001269" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [author_id](https://w3id.org/sssom/author_id) [0000-0001-9439-5346](https://orcid.org/0000-0001-9439-5346) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + +- [atlanto-occipital joint](http://purl.obolibrary.org/obo/UBERON_0000220) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "articulatio atlantooccipitalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Atlanto-occipital_joint" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### atrioventricular node `http://purl.obolibrary.org/obo/UBERON_0002352` +#### Removed +- [atrioventricular node](http://purl.obolibrary.org/obo/UBERON_0002352) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nodus atrioventricularis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Atrioventricular_node" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [atrioventricular node](http://purl.obolibrary.org/obo/UBERON_0002352) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nodus atrioventricularis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [atrioventricular node](http://purl.obolibrary.org/obo/UBERON_0002352) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nodus atrioventricularis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [atrioventricular node](http://purl.obolibrary.org/obo/UBERON_0002352) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nodus atrioventricularis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Atrioventricular_node" + + +### author_id `https://w3id.org/sssom/author_id` + +#### Added +- AnnotationProperty: [author_id](https://w3id.org/sssom/author_id) + + +### autonomic ganglion `http://purl.obolibrary.org/obo/UBERON_0001805` +#### Removed +- [autonomic ganglion](http://purl.obolibrary.org/obo/UBERON_0001805) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ganglion autonomicum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Autonomic_ganglion" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [autonomic ganglion](http://purl.obolibrary.org/obo/UBERON_0001805) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ganglion autonomicum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Autonomic_ganglion" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### autonomic nerve plexus `http://purl.obolibrary.org/obo/UBERON_0001816` +#### Removed +- [autonomic nerve plexus](http://purl.obolibrary.org/obo/UBERON_0001816) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "plexus visceralis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:5910" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [autonomic nerve plexus](http://purl.obolibrary.org/obo/UBERON_0001816) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "plexus autonomicus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:5910" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [autonomic nerve plexus](http://purl.obolibrary.org/obo/UBERON_0001816) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "plexus nervosus visceralis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:5910" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [autonomic nerve plexus](http://purl.obolibrary.org/obo/UBERON_0001816) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "plexus nervosus visceralis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:5910" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [autonomic nerve plexus](http://purl.obolibrary.org/obo/UBERON_0001816) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "plexus visceralis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:5910" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [autonomic nerve plexus](http://purl.obolibrary.org/obo/UBERON_0001816) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "plexus autonomicus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:5910" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### autonomic nervous system `http://purl.obolibrary.org/obo/UBERON_0002410` +#### Removed +- [autonomic nervous system](http://purl.obolibrary.org/obo/UBERON_0002410) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "divisio autonomica systematis nervosi peripherici" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Autonomic_nervous_system" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [autonomic nervous system](http://purl.obolibrary.org/obo/UBERON_0002410) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "divisio autonomica systematis nervosi peripherici" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Autonomic_nervous_system" + +- [autonomic nervous system](http://purl.obolibrary.org/obo/UBERON_0002410) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IDOMAL:0002126" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [LexicalMatching](https://w3id.org/semapv/vocab/LexicalMatching) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### axial skeleton plus cranial skeleton `http://purl.obolibrary.org/obo/UBERON_0005944` +#### Removed +- [axial skeleton plus cranial skeleton](http://purl.obolibrary.org/obo/UBERON_0005944) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "skeleton axiale" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Axial_skeleton" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [axial skeleton plus cranial skeleton](http://purl.obolibrary.org/obo/UBERON_0005944) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "skeleton axiale" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Axial_skeleton" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### axilla `http://purl.obolibrary.org/obo/UBERON_0009472` +#### Removed +- [axilla](http://purl.obolibrary.org/obo/UBERON_0009472) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "axilla" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Axilla" + +- [axilla](http://purl.obolibrary.org/obo/UBERON_0009472) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regio axillaris" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [axilla](http://purl.obolibrary.org/obo/UBERON_0009472) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "axilla" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Axilla" + +- [axilla](http://purl.obolibrary.org/obo/UBERON_0009472) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regio axillaris" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### axillary artery `http://purl.obolibrary.org/obo/UBERON_0001394` +#### Removed +- [axillary artery](http://purl.obolibrary.org/obo/UBERON_0001394) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "arteria axillaris" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Axillary_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [axillary artery](http://purl.obolibrary.org/obo/UBERON_0001394) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "arteria axillaris" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Axillary_artery" + + +### axillary nerve `http://purl.obolibrary.org/obo/UBERON_0001493` +#### Removed +- [axillary nerve](http://purl.obolibrary.org/obo/UBERON_0001493) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nervus axillaris" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Axillary_nerve" + +#### Added +- [axillary nerve](http://purl.obolibrary.org/obo/UBERON_0001493) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nervus axillaris" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Axillary_nerve" + + +### axillary vein `http://purl.obolibrary.org/obo/UBERON_0000985` +#### Removed +- [axillary vein](http://purl.obolibrary.org/obo/UBERON_0000985) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "vena axillaris" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Axillary_vein" + +#### Added +- [axillary vein](http://purl.obolibrary.org/obo/UBERON_0000985) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "vena axillaris" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Axillary_vein" + + +### axon tract `http://purl.obolibrary.org/obo/UBERON_0001018` +#### Removed +- [axon tract](http://purl.obolibrary.org/obo/UBERON_0001018) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005100" + +#### Added +- [axon tract](http://purl.obolibrary.org/obo/UBERON_0001018) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005100" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### basal cell `http://purl.obolibrary.org/obo/CL_0000646` + +#### Added +- [basal cell](http://purl.obolibrary.org/obo/CL_0000646) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### basal cell of epidermis `http://purl.obolibrary.org/obo/CL_0002187` + +#### Added +- [basal cell of epidermis](http://purl.obolibrary.org/obo/CL_0002187) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### basal cell of epithelium of trachea `http://purl.obolibrary.org/obo/CL_1000348` + +#### Added +- [basal cell of epithelium of trachea](http://purl.obolibrary.org/obo/CL_1000348) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### basal cell of prostate epithelium `http://purl.obolibrary.org/obo/CL_0002341` + +#### Added +- [basal cell of prostate epithelium](http://purl.obolibrary.org/obo/CL_0002341) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### basal epithelial cell of prostatic duct `http://purl.obolibrary.org/obo/CL_0002236` + +#### Added +- [basal epithelial cell of prostatic duct](http://purl.obolibrary.org/obo/CL_0002236) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### basal epithelial cell of tracheobronchial tree `http://purl.obolibrary.org/obo/CL_0002329` + +#### Added +- [basal epithelial cell of tracheobronchial tree](http://purl.obolibrary.org/obo/CL_0002329) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### basal forebrain `http://purl.obolibrary.org/obo/UBERON_0002743` +#### Removed +- [basal forebrain](http://purl.obolibrary.org/obo/UBERON_0002743) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "pars basalis telencephali" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Basal_forebrain" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [basal forebrain](http://purl.obolibrary.org/obo/UBERON_0002743) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D066187" + +#### Added +- [basal forebrain](http://purl.obolibrary.org/obo/UBERON_0002743) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "pars basalis telencephali" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Basal_forebrain" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [basal forebrain](http://purl.obolibrary.org/obo/UBERON_0002743) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D066187" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [author_id](https://w3id.org/sssom/author_id) [0000-0001-9439-5346](https://orcid.org/0000-0001-9439-5346) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### basal ganglion `http://purl.obolibrary.org/obo/UBERON_0002420` +#### Removed +- [basal ganglion](http://purl.obolibrary.org/obo/UBERON_0002420) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nuclei basales" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Basal_ganglia" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [basal ganglion](http://purl.obolibrary.org/obo/UBERON_0002420) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nuclei basales" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Basal_ganglia" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### basal nuclear complex `http://purl.obolibrary.org/obo/UBERON_0006098` +#### Removed +- [basal nuclear complex](http://purl.obolibrary.org/obo/UBERON_0006098) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "corpus striatum (Savel'ev)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:224" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [basal nuclear complex](http://purl.obolibrary.org/obo/UBERON_0006098) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ganglia basales" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:224" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [basal nuclear complex](http://purl.obolibrary.org/obo/UBERON_0006098) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D001479" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [LexicalMatching](https://w3id.org/semapv/vocab/LexicalMatching) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + +- [basal nuclear complex](http://purl.obolibrary.org/obo/UBERON_0006098) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "corpus striatum (Savel'ev)" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:224" + +- [basal nuclear complex](http://purl.obolibrary.org/obo/UBERON_0006098) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ganglia basales" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:224" + + +### basement membrane of epithelium `http://purl.obolibrary.org/obo/UBERON_0005769` +#### Removed +- [basement membrane of epithelium](http://purl.obolibrary.org/obo/UBERON_0005769) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "membrana basalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Basement_membrane" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [basement membrane of epithelium](http://purl.obolibrary.org/obo/UBERON_0005769) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "membrana basalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Basement_membrane" + + +### basicranium `http://purl.obolibrary.org/obo/UBERON_0002517` +#### Removed +- [basicranium](http://purl.obolibrary.org/obo/UBERON_0002517) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "basis cranii" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:52801" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Base_of_skull" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [basicranium](http://purl.obolibrary.org/obo/UBERON_0002517) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "basis cranii" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:52801" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Base_of_skull" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### basophil `http://purl.obolibrary.org/obo/CL_0000767` + +#### Added +- [basophil](http://purl.obolibrary.org/obo/CL_0000767) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### basophil mast progenitor cell `http://purl.obolibrary.org/obo/CL_0002028` + +#### Added +- [basophil mast progenitor cell](http://purl.obolibrary.org/obo/CL_0002028) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### bicarbonate channel activity `http://purl.obolibrary.org/obo/GO_0160133` + +#### Added +- [bicarbonate channel activity](http://purl.obolibrary.org/obo/GO_0160133) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) "https://github.com/geneontology/go-ontology/issues/26601"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + +- [bicarbonate channel activity](http://purl.obolibrary.org/obo/GO_0160133) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" + +- [bicarbonate channel activity](http://purl.obolibrary.org/obo/GO_0160133) [creation date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2023-12-13T00:09:44Z" + +- [bicarbonate channel activity](http://purl.obolibrary.org/obo/GO_0160133) [created by](http://www.geneontology.org/formats/oboInOwl#created_by) "rynl" + +- [bicarbonate channel activity](http://purl.obolibrary.org/obo/GO_0160133) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0160133" + +- [bicarbonate channel activity](http://purl.obolibrary.org/obo/GO_0160133) [label](http://www.w3.org/2000/01/rdf-schema#label) "bicarbonate channel activity" + +- [bicarbonate channel activity](http://purl.obolibrary.org/obo/GO_0160133) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Enables the facilitated diffusion of a bicarbonate (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:18400985" + +- Class: [bicarbonate channel activity](http://purl.obolibrary.org/obo/GO_0160133) + +- [bicarbonate channel activity](http://purl.obolibrary.org/obo/GO_0160133) EquivalentTo [channel activity](http://purl.obolibrary.org/obo/GO_0015267) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [CHEBI_17544](http://purl.obolibrary.org/obo/CHEBI_17544)) + +- [bicarbonate channel activity](http://purl.obolibrary.org/obo/GO_0160133) SubClassOf [bicarbonate transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0015106) + +- [bicarbonate channel activity](http://purl.obolibrary.org/obo/GO_0160133) SubClassOf [channel activity](http://purl.obolibrary.org/obo/GO_0015267) + + +### biliary tree `http://purl.obolibrary.org/obo/UBERON_0001173` + +#### Added +- [biliary tree](http://purl.obolibrary.org/obo/UBERON_0001173) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D001659" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [LexicalMatching](https://w3id.org/semapv/vocab/LexicalMatching) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### bipolar neuron `http://purl.obolibrary.org/obo/CL_0000103` + +#### Added +- [bipolar neuron](http://purl.obolibrary.org/obo/CL_0000103) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### bladder cell `http://purl.obolibrary.org/obo/CL_1001319` + +#### Added +- [bladder cell](http://purl.obolibrary.org/obo/CL_1001319) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### bladder urothelial cell `http://purl.obolibrary.org/obo/CL_1001428` + +#### Added +- [bladder urothelial cell](http://purl.obolibrary.org/obo/CL_1001428) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### blastocyst `http://purl.obolibrary.org/obo/UBERON_0000358` +#### Removed +- [blastocyst](http://purl.obolibrary.org/obo/UBERON_0000358) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "blastocystis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Blastocyst" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [blastocyst](http://purl.obolibrary.org/obo/UBERON_0000358) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "blastocystis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Blastocyst" + + +### blood brain barrier `http://purl.obolibrary.org/obo/UBERON_0000120` +#### Removed +- [blood brain barrier](http://purl.obolibrary.org/obo/UBERON_0000120) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D001812" + +#### Added +- [blood brain barrier](http://purl.obolibrary.org/obo/UBERON_0000120) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D001812" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [author_id](https://w3id.org/sssom/author_id) [0000-0001-9439-5346](https://orcid.org/0000-0001-9439-5346) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### blood cell `http://purl.obolibrary.org/obo/CL_0000081` + +#### Added +- [blood cell](http://purl.obolibrary.org/obo/CL_0000081) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### blood coagulation `http://purl.obolibrary.org/obo/GO_0007596` +#### Removed +- [blood coagulation](http://purl.obolibrary.org/obo/GO_0007596) EquivalentTo [coagulation](http://purl.obolibrary.org/obo/GO_0050817) and ([has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [blood clot](http://purl.obolibrary.org/obo/UBERON_0010210)) + +- [blood coagulation](http://purl.obolibrary.org/obo/GO_0007596) SubClassOf [has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [blood clot](http://purl.obolibrary.org/obo/UBERON_0010210) + +#### Added +- [blood coagulation](http://purl.obolibrary.org/obo/GO_0007596) EquivalentTo [coagulation](http://purl.obolibrary.org/obo/GO_0050817) and ([results in assembly of](http://purl.obolibrary.org/obo/RO_0002588) some [blood clot](http://purl.obolibrary.org/obo/UBERON_0010210)) + +- [blood coagulation](http://purl.obolibrary.org/obo/GO_0007596) SubClassOf [results in assembly of](http://purl.obolibrary.org/obo/RO_0002588) some [blood clot](http://purl.obolibrary.org/obo/UBERON_0010210) + + +### blood nerve barrier `http://purl.obolibrary.org/obo/UBERON_0003209` +#### Removed +- [blood nerve barrier](http://purl.obolibrary.org/obo/UBERON_0003209) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D049428" + +#### Added +- [blood nerve barrier](http://purl.obolibrary.org/obo/UBERON_0003209) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D049428" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [author_id](https://w3id.org/sssom/author_id) [0000-0001-9439-5346](https://orcid.org/0000-0001-9439-5346) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### blood vessel `http://purl.obolibrary.org/obo/UBERON_0001981` +#### Removed +- [blood vessel](http://purl.obolibrary.org/obo/UBERON_0001981) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vas sanguineum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Blood_vessel" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [blood vessel](http://purl.obolibrary.org/obo/UBERON_0001981) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vas sanguineum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Blood_vessel" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### blood vessel endothelial cell `http://purl.obolibrary.org/obo/CL_0000071` + +#### Added +- [blood vessel endothelial cell](http://purl.obolibrary.org/obo/CL_0000071) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### blood vessel endothelium `http://purl.obolibrary.org/obo/UBERON_0004638` + +#### Added +- [blood vessel endothelium](http://purl.obolibrary.org/obo/UBERON_0004638) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [human_reference_atlas](http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas) + +- [blood vessel endothelium](http://purl.obolibrary.org/obo/UBERON_0004638) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606) + + +### body of stomach `http://purl.obolibrary.org/obo/UBERON_0001161` +#### Removed +- [body of stomach](http://purl.obolibrary.org/obo/UBERON_0001161) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "corpus gastricum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0000505" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Body_of_stomach" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [body of stomach](http://purl.obolibrary.org/obo/UBERON_0001161) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "corpus gastricum" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0000505" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Body_of_stomach" + + +### body proper `http://purl.obolibrary.org/obo/UBERON_0013702` +#### Removed +- [body proper](http://purl.obolibrary.org/obo/UBERON_0013702) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [human_reference_atlas](http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas) + +- [body proper](http://purl.obolibrary.org/obo/UBERON_0013702) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606) + + + +### bone marrow `http://purl.obolibrary.org/obo/UBERON_0002371` +#### Removed +- [bone marrow](http://purl.obolibrary.org/obo/UBERON_0002371) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "medulla ossea" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0000141" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:9608" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [bone marrow](http://purl.obolibrary.org/obo/UBERON_0002371) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "medulla ossium" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0000141" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Bone_marrow" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [bone marrow](http://purl.obolibrary.org/obo/UBERON_0002371) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "medulla ossea" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0000141" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:9608" + +- [bone marrow](http://purl.obolibrary.org/obo/UBERON_0002371) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "medulla ossium" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0000141" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Bone_marrow" + + +### bone marrow cell `http://purl.obolibrary.org/obo/CL_0002092` + +#### Added +- [bone marrow cell](http://purl.obolibrary.org/obo/CL_0002092) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### bony labyrinth `http://purl.obolibrary.org/obo/UBERON_0001839` +#### Removed +- [bony labyrinth](http://purl.obolibrary.org/obo/UBERON_0001839) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "labyrinthus osseus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Bony_labyrinth" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [bony labyrinth](http://purl.obolibrary.org/obo/UBERON_0001839) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "labyrinthus osseus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Bony_labyrinth" + + +### bony vertebral centrum `http://purl.obolibrary.org/obo/UBERON_0001075` +#### Removed +- [bony vertebral centrum](http://purl.obolibrary.org/obo/UBERON_0001075) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "corpus vertebra" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [bony vertebral centrum](http://purl.obolibrary.org/obo/UBERON_0001075) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "corpus vertebra" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### brachial nerve plexus `http://purl.obolibrary.org/obo/UBERON_0001814` +#### Removed +- [brachial nerve plexus](http://purl.obolibrary.org/obo/UBERON_0001814) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "plexus brachialis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Brachial_plexus" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [brachial nerve plexus](http://purl.obolibrary.org/obo/UBERON_0001814) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "plexus brachialis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Brachial_plexus" + + +### brachiocephalic artery `http://purl.obolibrary.org/obo/UBERON_0001529` +#### Removed +- [brachiocephalic artery](http://purl.obolibrary.org/obo/UBERON_0001529) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "truncus brachiocephalicus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:3932" + +- [brachiocephalic artery](http://purl.obolibrary.org/obo/UBERON_0001529) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "truncus brachiocephalicus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Brachiocephalic_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [brachiocephalic artery](http://purl.obolibrary.org/obo/UBERON_0001529) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "truncus brachiocephalicus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Brachiocephalic_artery" + +- [brachiocephalic artery](http://purl.obolibrary.org/obo/UBERON_0001529) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "truncus brachiocephalicus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:3932" + + +### brachiocephalic vein `http://purl.obolibrary.org/obo/UBERON_0003711` +#### Removed +- [brachiocephalic vein](http://purl.obolibrary.org/obo/UBERON_0003711) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vena brachiocephalica" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Brachiocephalic_vein" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [brachiocephalic vein](http://purl.obolibrary.org/obo/UBERON_0003711) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "venae anonyma" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Brachiocephalic_vein" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [brachiocephalic vein](http://purl.obolibrary.org/obo/UBERON_0003711) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "venae anonyma" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Brachiocephalic_vein" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [brachiocephalic vein](http://purl.obolibrary.org/obo/UBERON_0003711) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vena brachiocephalica" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Brachiocephalic_vein" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### brain `http://purl.obolibrary.org/obo/UBERON_0000955` +#### Removed +- [brain](http://purl.obolibrary.org/obo/UBERON_0000955) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005095" + +#### Added +- [brain](http://purl.obolibrary.org/obo/UBERON_0000955) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005095" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### brain arachnoid mater `http://purl.obolibrary.org/obo/UBERON_0005397` +#### Removed +- [brain arachnoid mater](http://purl.obolibrary.org/obo/UBERON_0005397) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "arachnoidea mater encephali" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:83981" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [brain arachnoid mater](http://purl.obolibrary.org/obo/UBERON_0005397) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "arachnoidea mater cranialis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:83981" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [brain arachnoid mater](http://purl.obolibrary.org/obo/UBERON_0005397) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "arachnoidea mater cranialis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:83981" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [brain arachnoid mater](http://purl.obolibrary.org/obo/UBERON_0005397) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "arachnoidea mater encephali" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:83981" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### brain dura mater `http://purl.obolibrary.org/obo/UBERON_0002092` +#### Removed +- [brain dura mater](http://purl.obolibrary.org/obo/UBERON_0002092) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "dura mater cranialis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:71236" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [brain dura mater](http://purl.obolibrary.org/obo/UBERON_0002092) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "dura mater cranialis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:71236" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### brain pericyte `http://purl.obolibrary.org/obo/CL_2000043` + +#### Added +- [brain pericyte](http://purl.obolibrary.org/obo/CL_2000043) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### brainstem `http://purl.obolibrary.org/obo/UBERON_0002298` +#### Removed +- [brainstem](http://purl.obolibrary.org/obo/UBERON_0002298) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "lamina medullaris accessoria" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:236" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [brainstem](http://purl.obolibrary.org/obo/UBERON_0002298) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "truncus encephalicus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0000146" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [brainstem](http://purl.obolibrary.org/obo/UBERON_0002298) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "lamina medullaris incompleta pallidi" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:236" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [brainstem](http://purl.obolibrary.org/obo/UBERON_0002298) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "lamina pallidi incompleta" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:236" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [brainstem](http://purl.obolibrary.org/obo/UBERON_0002298) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "lamella pallidi incompleta" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:236" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [brainstem](http://purl.obolibrary.org/obo/UBERON_0002298) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "truncus encephali" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Brainstem" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [brainstem](http://purl.obolibrary.org/obo/UBERON_0002298) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "truncus encephalicus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0000146" + +- [brainstem](http://purl.obolibrary.org/obo/UBERON_0002298) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "lamina medullaris incompleta pallidi" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:236" + +- [brainstem](http://purl.obolibrary.org/obo/UBERON_0002298) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "lamella pallidi incompleta" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:236" + +- [brainstem](http://purl.obolibrary.org/obo/UBERON_0002298) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "lamina medullaris accessoria" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:236" + +- [brainstem](http://purl.obolibrary.org/obo/UBERON_0002298) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "truncus encephali" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Brainstem" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [brainstem](http://purl.obolibrary.org/obo/UBERON_0002298) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "lamina pallidi incompleta" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:236" + + +### breast `http://purl.obolibrary.org/obo/UBERON_0000310` +#### Removed +- [breast](http://purl.obolibrary.org/obo/UBERON_0000310) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "mamma" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Breast" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [breast](http://purl.obolibrary.org/obo/UBERON_0000310) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "mamma" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Breast" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### broad ligament of uterus `http://purl.obolibrary.org/obo/UBERON_0012332` +#### Removed +- [broad ligament of uterus](http://purl.obolibrary.org/obo/UBERON_0012332) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ligamentum latum uteri" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [broad ligament of uterus](http://purl.obolibrary.org/obo/UBERON_0012332) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ligamentum latum uteri" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### bronchial artery `http://purl.obolibrary.org/obo/UBERON_0002040` +#### Removed +- [bronchial artery](http://purl.obolibrary.org/obo/UBERON_0002040) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "rami bronchiales partis thoracicae aortae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Bronchial_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [bronchial artery](http://purl.obolibrary.org/obo/UBERON_0002040) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteriae bronchiales" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Bronchial_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [bronchial artery](http://purl.obolibrary.org/obo/UBERON_0002040) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteriae bronchiales" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Bronchial_artery" + +- [bronchial artery](http://purl.obolibrary.org/obo/UBERON_0002040) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "rami bronchiales partis thoracicae aortae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Bronchial_artery" + + +### bronchial epithelial cell `http://purl.obolibrary.org/obo/CL_0002328` + +#### Added +- [bronchial epithelial cell](http://purl.obolibrary.org/obo/CL_0002328) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### bronchial goblet cell `http://purl.obolibrary.org/obo/CL_1000312` + +#### Added +- [bronchial goblet cell](http://purl.obolibrary.org/obo/CL_1000312) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### bronchial mucosa `http://purl.obolibrary.org/obo/UBERON_0000410` +#### Removed +- [bronchial mucosa](http://purl.obolibrary.org/obo/UBERON_0000410) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica mucosa bronchi" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:62652" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [bronchial mucosa](http://purl.obolibrary.org/obo/UBERON_0000410) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica mucosa bronchi" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:62652" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### bronchial smooth muscle cell `http://purl.obolibrary.org/obo/CL_0002598` + +#### Added +- [bronchial smooth muscle cell](http://purl.obolibrary.org/obo/CL_0002598) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### bronchiole `http://purl.obolibrary.org/obo/UBERON_0002186` +#### Removed +- [bronchiole](http://purl.obolibrary.org/obo/UBERON_0002186) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D055745" + +#### Added +- [bronchiole](http://purl.obolibrary.org/obo/UBERON_0002186) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D055745" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [author_id](https://w3id.org/sssom/author_id) [0000-0001-9439-5346](https://orcid.org/0000-0001-9439-5346) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### bronchus `http://purl.obolibrary.org/obo/UBERON_0002185` + +#### Added +- [bronchus](http://purl.obolibrary.org/obo/UBERON_0002185) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606) + +- [bronchus](http://purl.obolibrary.org/obo/UBERON_0002185) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [human_reference_atlas](http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas) + + +### bronchus fibroblast of lung `http://purl.obolibrary.org/obo/CL_2000093` + +#### Added +- [bronchus fibroblast of lung](http://purl.obolibrary.org/obo/CL_2000093) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### brown adipose tissue `http://purl.obolibrary.org/obo/UBERON_0001348` +#### Removed +- [brown adipose tissue](http://purl.obolibrary.org/obo/UBERON_0001348) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "textus adiposus fuscus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Brown_adipose_tissue" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [brown adipose tissue](http://purl.obolibrary.org/obo/UBERON_0001348) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "textus adiposus fuscus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Brown_adipose_tissue" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### brush cell `http://purl.obolibrary.org/obo/CL_0002204` + +#### Added +- [brush cell](http://purl.obolibrary.org/obo/CL_0002204) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### brush cell of epithelium proper of large intestine `http://purl.obolibrary.org/obo/CL_0002203` + +#### Added +- [brush cell of epithelium proper of large intestine](http://purl.obolibrary.org/obo/CL_0002203) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### brush cell of trachea `http://purl.obolibrary.org/obo/CL_0002207` + +#### Added +- [brush cell of trachea](http://purl.obolibrary.org/obo/CL_0002207) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### brush cell of trachebronchial tree `http://purl.obolibrary.org/obo/CL_0002075` + +#### Added +- [brush cell of trachebronchial tree](http://purl.obolibrary.org/obo/CL_0002075) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### bundle of His `http://purl.obolibrary.org/obo/UBERON_0002353` +#### Removed +- [bundle of His](http://purl.obolibrary.org/obo/UBERON_0002353) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "fasciculus atrioventricularis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Bundle_of_His" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [bundle of His](http://purl.obolibrary.org/obo/UBERON_0002353) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "fasciculus atrioventricularis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Bundle_of_His" + + +### calcium ion import `http://purl.obolibrary.org/obo/GO_0070509` + +#### Added +- [calcium ion import](http://purl.obolibrary.org/obo/GO_0070509) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) "https://github.com/geneontology/go-ontology/issues/23015"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + +- [calcium ion import](http://purl.obolibrary.org/obo/GO_0070509) [label](http://www.w3.org/2000/01/rdf-schema#label) "calcium ion import" + +- [calcium ion import](http://purl.obolibrary.org/obo/GO_0070509) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "calcium ion uptake" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- [calcium ion import](http://purl.obolibrary.org/obo/GO_0070509) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [calcium ion import](http://purl.obolibrary.org/obo/GO_0070509) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The directed movement of calcium ions into a cell or organelle." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- [calcium ion import](http://purl.obolibrary.org/obo/GO_0070509) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "transmembrane calcium influx" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:tb" + +- [calcium ion import](http://purl.obolibrary.org/obo/GO_0070509) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0070509" + +- Class: [calcium ion import](http://purl.obolibrary.org/obo/GO_0070509) + +- [calcium ion import](http://purl.obolibrary.org/obo/GO_0070509) SubClassOf [calcium ion transport](http://purl.obolibrary.org/obo/GO_0006816) + + +### calcium ion import across plasma membrane `http://purl.obolibrary.org/obo/GO_0098703` + +#### Added +- [calcium ion import across plasma membrane](http://purl.obolibrary.org/obo/GO_0098703) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) "https://github.com/geneontology/go-ontology/issues/24965"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + +- [calcium ion import across plasma membrane](http://purl.obolibrary.org/obo/GO_0098703) SubClassOf [calcium ion import](http://purl.obolibrary.org/obo/GO_0070509) + +- [calcium ion import across plasma membrane](http://purl.obolibrary.org/obo/GO_0098703) SubClassOf [calcium ion import into cytosol](http://purl.obolibrary.org/obo/GO_1902656) + + +### calcium ion import into cytosol `http://purl.obolibrary.org/obo/GO_1902656` + +#### Added +- [calcium ion import into cytosol](http://purl.obolibrary.org/obo/GO_1902656) [creation date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2014-01-22T13:41:11Z" + +- [calcium ion import into cytosol](http://purl.obolibrary.org/obo/GO_1902656) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The directed movement of calcium ion into a cytosol." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:vw" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GO_REF:0000075" + +- [calcium ion import into cytosol](http://purl.obolibrary.org/obo/GO_1902656) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [calcium ion import into cytosol](http://purl.obolibrary.org/obo/GO_1902656) [label](http://www.w3.org/2000/01/rdf-schema#label) "calcium ion import into cytosol" + +- [calcium ion import into cytosol](http://purl.obolibrary.org/obo/GO_1902656) [created by](http://www.geneontology.org/formats/oboInOwl#created_by) "pr" + +- [calcium ion import into cytosol](http://purl.obolibrary.org/obo/GO_1902656) [has_broad_synonym](http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym) "calcium import into cytosol" + +- [calcium ion import into cytosol](http://purl.obolibrary.org/obo/GO_1902656) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1902656" + +- Class: [calcium ion import into cytosol](http://purl.obolibrary.org/obo/GO_1902656) + +- [calcium ion import into cytosol](http://purl.obolibrary.org/obo/GO_1902656) SubClassOf [calcium ion transport](http://purl.obolibrary.org/obo/GO_0006816) + +- [calcium ion import into cytosol](http://purl.obolibrary.org/obo/GO_1902656) SubClassOf [has target end location](http://purl.obolibrary.org/obo/RO_0002339) some [cytosol](http://purl.obolibrary.org/obo/GO_0005829) + + +### calcium-mediated signaling `http://purl.obolibrary.org/obo/GO_0019722` +#### Removed +- [calcium-mediated signaling](http://purl.obolibrary.org/obo/GO_0019722) SubClassOf [second-messenger-mediated signaling](http://purl.obolibrary.org/obo/GO_0019932) + +#### Added +- [calcium-mediated signaling](http://purl.obolibrary.org/obo/GO_0019722) SubClassOf [intracellular signaling cassette](http://purl.obolibrary.org/obo/GO_0141124) + + +### camera-type eye `http://purl.obolibrary.org/obo/UBERON_0000019` +#### Removed +- [camera-type eye](http://purl.obolibrary.org/obo/UBERON_0000019) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regio orbitalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:54448" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [camera-type eye](http://purl.obolibrary.org/obo/UBERON_0000019) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regio orbitalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:54448" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### capillary endothelial cell `http://purl.obolibrary.org/obo/CL_0002144` + +#### Added +- [capillary endothelial cell](http://purl.obolibrary.org/obo/CL_0002144) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### capsule of lens `http://purl.obolibrary.org/obo/UBERON_0001804` +#### Removed +- [capsule of lens](http://purl.obolibrary.org/obo/UBERON_0001804) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "capsula lentis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [capsule of lens](http://purl.obolibrary.org/obo/UBERON_0001804) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "capsula lentis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### capsule of liver `http://purl.obolibrary.org/obo/UBERON_0016479` +#### Removed +- [capsule of liver](http://purl.obolibrary.org/obo/UBERON_0016479) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "capsula fibrosa perivascularis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Fibrous_capsule_of_Glisson" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [capsule of liver](http://purl.obolibrary.org/obo/UBERON_0016479) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica fibrosa hepatis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:15813" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [capsule of liver](http://purl.obolibrary.org/obo/UBERON_0016479) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "capsula fibrosa perivascularis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Fibrous_capsule_of_Glisson" + +- [capsule of liver](http://purl.obolibrary.org/obo/UBERON_0016479) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica fibrosa hepatis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:15813" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### capsule of lymph node `http://purl.obolibrary.org/obo/UBERON_0002194` +#### Removed +- [capsule of lymph node](http://purl.obolibrary.org/obo/UBERON_0002194) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "capsula nodi lymphoidei" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:74604" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [capsule of lymph node](http://purl.obolibrary.org/obo/UBERON_0002194) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "capsula nodi lymphoidei" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:74604" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### capsule of thyroid gland `http://purl.obolibrary.org/obo/UBERON_0001746` +#### Removed +- [capsule of thyroid gland](http://purl.obolibrary.org/obo/UBERON_0001746) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "capsula fibrosa glandulae thyroideae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:55513" + +#### Added +- [capsule of thyroid gland](http://purl.obolibrary.org/obo/UBERON_0001746) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "capsula fibrosa glandulae thyroideae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:55513" + + +### carbohydrate derivative metabolic process `http://purl.obolibrary.org/obo/GO_1901135` +#### Removed +- [carbohydrate derivative metabolic process](http://purl.obolibrary.org/obo/GO_1901135) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [prokaryote_subset](http://purl.obolibrary.org/obo/go#prokaryote_subset) + +#### Added +- [carbohydrate derivative metabolic process](http://purl.obolibrary.org/obo/GO_1901135) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_prokaryote](http://purl.obolibrary.org/obo/go#goslim_prokaryote) + + +### carbohydrate metabolic process `http://purl.obolibrary.org/obo/GO_0005975` +#### Removed +- [carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0005975) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [prokaryote_subset](http://purl.obolibrary.org/obo/go#prokaryote_subset) + +#### Added +- [carbohydrate metabolic process](http://purl.obolibrary.org/obo/GO_0005975) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_prokaryote](http://purl.obolibrary.org/obo/go#goslim_prokaryote) + + +### cardia of stomach `http://purl.obolibrary.org/obo/UBERON_0001162` +#### Removed +- [cardia of stomach](http://purl.obolibrary.org/obo/UBERON_0001162) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pars cardiaca gastricae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:14561" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [cardia of stomach](http://purl.obolibrary.org/obo/UBERON_0001162) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "antrum cardiacum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Cardia" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [cardia of stomach](http://purl.obolibrary.org/obo/UBERON_0001162) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "antrum cardiacum" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Cardia" + +- [cardia of stomach](http://purl.obolibrary.org/obo/UBERON_0001162) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pars cardiaca gastricae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:14561" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### cardiac Purkinje fiber `http://purl.obolibrary.org/obo/UBERON_0002354` +#### Removed +- [cardiac Purkinje fiber](http://purl.obolibrary.org/obo/UBERON_0002354) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "myofibra conducens cardiacus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [cardiac Purkinje fiber](http://purl.obolibrary.org/obo/UBERON_0002354) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "myofibra conducens cardiacus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### cardiac endothelial cell `http://purl.obolibrary.org/obo/CL_0010008` + +#### Added +- [cardiac endothelial cell](http://purl.obolibrary.org/obo/CL_0010008) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### cardiac mesenchymal cell `http://purl.obolibrary.org/obo/CL_0000569` + +#### Added +- [cardiac mesenchymal cell](http://purl.obolibrary.org/obo/CL_0000569) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### cardiac muscle cell `http://purl.obolibrary.org/obo/CL_0000746` + +#### Added +- [cardiac muscle cell](http://purl.obolibrary.org/obo/CL_0000746) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### cardiac muscle myoblast `http://purl.obolibrary.org/obo/CL_0000513` + +#### Added +- [cardiac muscle myoblast](http://purl.obolibrary.org/obo/CL_0000513) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### cardiac nerve plexus `http://purl.obolibrary.org/obo/UBERON_0002008` +#### Removed +- [cardiac nerve plexus](http://purl.obolibrary.org/obo/UBERON_0002008) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "plexus cardiacus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Cardiac_plexus" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [cardiac nerve plexus](http://purl.obolibrary.org/obo/UBERON_0002008) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "plexus cardiacus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Cardiac_plexus" + + +### cardiac neuron `http://purl.obolibrary.org/obo/CL_0010022` + +#### Added +- [cardiac neuron](http://purl.obolibrary.org/obo/CL_0010022) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### cardiac skeleton `http://purl.obolibrary.org/obo/UBERON_0004292` +#### Removed +- [cardiac skeleton](http://purl.obolibrary.org/obo/UBERON_0004292) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "anulus fibrosus sinister cordis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Cardiac_skeleton" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [cardiac skeleton](http://purl.obolibrary.org/obo/UBERON_0004292) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "trigona fibrosa" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Cardiac_skeleton" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [cardiac skeleton](http://purl.obolibrary.org/obo/UBERON_0004292) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "anulus fibrosus dexter cordis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Cardiac_skeleton" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [cardiac skeleton](http://purl.obolibrary.org/obo/UBERON_0004292) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "trigonum fibrosum dextrum cordis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Cardiac_skeleton" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [cardiac skeleton](http://purl.obolibrary.org/obo/UBERON_0004292) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "trigonum fibrosum sinistrum cordis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Cardiac_skeleton" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [cardiac skeleton](http://purl.obolibrary.org/obo/UBERON_0004292) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "anulus fibrosus sinister cordis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Cardiac_skeleton" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [cardiac skeleton](http://purl.obolibrary.org/obo/UBERON_0004292) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "anulus fibrosus dexter cordis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Cardiac_skeleton" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [cardiac skeleton](http://purl.obolibrary.org/obo/UBERON_0004292) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "trigonum fibrosum dextrum cordis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Cardiac_skeleton" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [cardiac skeleton](http://purl.obolibrary.org/obo/UBERON_0004292) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "trigona fibrosa" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Cardiac_skeleton" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [cardiac skeleton](http://purl.obolibrary.org/obo/UBERON_0004292) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "trigonum fibrosum sinistrum cordis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Cardiac_skeleton" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### cardiac valve cell `http://purl.obolibrary.org/obo/CL_1000147` + +#### Added +- [cardiac valve cell](http://purl.obolibrary.org/obo/CL_1000147) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### carotid canal `http://purl.obolibrary.org/obo/UBERON_0006668` +#### Removed +- [carotid canal](http://purl.obolibrary.org/obo/UBERON_0006668) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "canalis caroticus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Carotid_canal" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [carotid canal](http://purl.obolibrary.org/obo/UBERON_0006668) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "canalis caroticus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Carotid_canal" + + +### carpal region `http://purl.obolibrary.org/obo/UBERON_0004452` +#### Removed +- [carpal region](http://purl.obolibrary.org/obo/UBERON_0004452) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "articulatio radiocarpea" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Wrist" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [carpal region](http://purl.obolibrary.org/obo/UBERON_0004452) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regio carpalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:24922" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [carpal region](http://purl.obolibrary.org/obo/UBERON_0004452) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "articulatio radiocarpea" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Wrist" + +- [carpal region](http://purl.obolibrary.org/obo/UBERON_0004452) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regio carpalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:24922" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### carpal skeleton `http://purl.obolibrary.org/obo/UBERON_0009880` +#### Removed +- [carpal skeleton](http://purl.obolibrary.org/obo/UBERON_0009880) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ossa carpi" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Carpus" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [carpal skeleton](http://purl.obolibrary.org/obo/UBERON_0009880) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ossa carpi" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Carpus" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### carpometacarpal joint `http://purl.obolibrary.org/obo/UBERON_0011119` +#### Removed +- [carpometacarpal joint](http://purl.obolibrary.org/obo/UBERON_0011119) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D052737" + +- [carpometacarpal joint](http://purl.obolibrary.org/obo/UBERON_0011119) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "articulationes carpometacarpeæ" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Carpometacarpal_joint" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [carpometacarpal joint](http://purl.obolibrary.org/obo/UBERON_0011119) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "articulationes carpometacarpeæ" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Carpometacarpal_joint" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [carpometacarpal joint](http://purl.obolibrary.org/obo/UBERON_0011119) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D052737" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [author_id](https://w3id.org/sssom/author_id) [0000-0001-9439-5346](https://orcid.org/0000-0001-9439-5346) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### cartilaginous joint `http://purl.obolibrary.org/obo/UBERON_0002213` +#### Removed +- [cartilaginous joint](http://purl.obolibrary.org/obo/UBERON_0002213) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "junctura cartilaginea" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Cartilaginous_joint" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [cartilaginous joint](http://purl.obolibrary.org/obo/UBERON_0002213) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "junctura cartilaginea" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Cartilaginous_joint" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### catalytic activity, acting on DNA `http://purl.obolibrary.org/obo/GO_0140097` +#### Removed +- [catalytic activity, acting on DNA](http://purl.obolibrary.org/obo/GO_0140097) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [prokaryote_subset](http://purl.obolibrary.org/obo/go#prokaryote_subset) + +#### Added +- [catalytic activity, acting on DNA](http://purl.obolibrary.org/obo/GO_0140097) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_prokaryote](http://purl.obolibrary.org/obo/go#goslim_prokaryote) + + +### catalytic activity, acting on RNA `http://purl.obolibrary.org/obo/GO_0140098` +#### Removed +- [catalytic activity, acting on RNA](http://purl.obolibrary.org/obo/GO_0140098) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [prokaryote_subset](http://purl.obolibrary.org/obo/go#prokaryote_subset) + +#### Added +- [catalytic activity, acting on RNA](http://purl.obolibrary.org/obo/GO_0140098) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_prokaryote](http://purl.obolibrary.org/obo/go#goslim_prokaryote) + + +### catalytic activity, acting on a protein `http://purl.obolibrary.org/obo/GO_0140096` +#### Removed +- [catalytic activity, acting on a protein](http://purl.obolibrary.org/obo/GO_0140096) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [prokaryote_subset](http://purl.obolibrary.org/obo/go#prokaryote_subset) + +#### Added +- [catalytic activity, acting on a protein](http://purl.obolibrary.org/obo/GO_0140096) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_prokaryote](http://purl.obolibrary.org/obo/go#goslim_prokaryote) + + +### caudal ganglionic eminence derived GABAergic cortical interneuron `http://purl.obolibrary.org/obo/CL_4023070` + +#### Added +- [caudal ganglionic eminence derived GABAergic cortical interneuron](http://purl.obolibrary.org/obo/CL_4023070) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### caudal segment of spinal cord `http://purl.obolibrary.org/obo/UBERON_0005845` +#### Removed +- [caudal segment of spinal cord](http://purl.obolibrary.org/obo/UBERON_0005845) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pars coccygea medullae spinalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:256635" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [caudal segment of spinal cord](http://purl.obolibrary.org/obo/UBERON_0005845) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "segmenta coccygea" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:1656" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [caudal segment of spinal cord](http://purl.obolibrary.org/obo/UBERON_0005845) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "segmenta coccygea medullae spinalis [1-3]" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:256635" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [caudal segment of spinal cord](http://purl.obolibrary.org/obo/UBERON_0005845) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "segmenta coccygea medullae spinalis [1-3]" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:256635" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [caudal segment of spinal cord](http://purl.obolibrary.org/obo/UBERON_0005845) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pars coccygea medullae spinalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:256635" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [caudal segment of spinal cord](http://purl.obolibrary.org/obo/UBERON_0005845) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "segmenta coccygea" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:1656" + + +### caudate nucleus `http://purl.obolibrary.org/obo/UBERON_0001873` +#### Removed +- [caudate nucleus](http://purl.obolibrary.org/obo/UBERON_0001873) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus caudatus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Caudate_nucleus" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0000211" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [caudate nucleus](http://purl.obolibrary.org/obo/UBERON_0001873) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus caudatus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Caudate_nucleus" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0000211" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### cavernous artery `http://purl.obolibrary.org/obo/UBERON_0000457` +#### Removed +- [cavernous artery](http://purl.obolibrary.org/obo/UBERON_0000457) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ramus sinus cavernosi (pars cavernosa) (arteria carotis interna)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:70527" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [cavernous artery](http://purl.obolibrary.org/obo/UBERON_0000457) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ramus sinus cavernosi (pars cavernosa) (arteria carotis interna)" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:70527" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### cavity of pharynx `http://purl.obolibrary.org/obo/UBERON_0001731` +#### Removed +- [cavity of pharynx](http://purl.obolibrary.org/obo/UBERON_0001731) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cavitas pharyngealis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [cavity of pharynx](http://purl.obolibrary.org/obo/UBERON_0001731) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cavitas pharyngealis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### celiac artery `http://purl.obolibrary.org/obo/UBERON_0001640` +#### Removed +- [celiac artery](http://purl.obolibrary.org/obo/UBERON_0001640) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria coeliaca" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Celiac_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [celiac artery](http://purl.obolibrary.org/obo/UBERON_0001640) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "truncus cœliacus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Celiac_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [celiac artery](http://purl.obolibrary.org/obo/UBERON_0001640) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "truncus coeliacus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Celiac_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [celiac artery](http://purl.obolibrary.org/obo/UBERON_0001640) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria cœliaca" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Celiac_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [celiac artery](http://purl.obolibrary.org/obo/UBERON_0001640) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "truncus cœliacus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Celiac_artery" + +- [celiac artery](http://purl.obolibrary.org/obo/UBERON_0001640) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "truncus coeliacus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Celiac_artery" + +- [celiac artery](http://purl.obolibrary.org/obo/UBERON_0001640) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria cœliaca" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Celiac_artery" + +- [celiac artery](http://purl.obolibrary.org/obo/UBERON_0001640) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria coeliaca" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Celiac_artery" + + +### cell `http://purl.obolibrary.org/obo/CL_0000000` + +#### Added +- [cell](http://purl.obolibrary.org/obo/CL_0000000) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### cell adhesion `http://purl.obolibrary.org/obo/GO_0007155` +#### Removed +- [cell adhesion](http://purl.obolibrary.org/obo/GO_0007155) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [prokaryote_subset](http://purl.obolibrary.org/obo/go#prokaryote_subset) + +#### Added +- [cell adhesion](http://purl.obolibrary.org/obo/GO_0007155) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_prokaryote](http://purl.obolibrary.org/obo/go#goslim_prokaryote) + + +### cell adhesion mediator activity `http://purl.obolibrary.org/obo/GO_0098631` +#### Removed +- [cell adhesion mediator activity](http://purl.obolibrary.org/obo/GO_0098631) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [prokaryote_subset](http://purl.obolibrary.org/obo/go#prokaryote_subset) + +#### Added +- [cell adhesion mediator activity](http://purl.obolibrary.org/obo/GO_0098631) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_prokaryote](http://purl.obolibrary.org/obo/go#goslim_prokaryote) + + +### cell cluster organ `http://purl.obolibrary.org/obo/UBERON_0010001` +#### Removed +- [cell cluster organ](http://purl.obolibrary.org/obo/UBERON_0010001) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007229" + +#### Added +- [cell cluster organ](http://purl.obolibrary.org/obo/UBERON_0010001) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007229" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### cell death `http://purl.obolibrary.org/obo/GO_0008219` +#### Removed +- [cell death](http://purl.obolibrary.org/obo/GO_0008219) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "This term should not be used for direct annotation, it is currently kept in GO as a placeholder for describing cell death phenotypes in uPHENO. When information is provided on a programmed cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'). Unintentional cell death, i.e. cell death caused by injury, ageing, or cell phenotypes observed as a result of a pathological mutation in an essential gene should NOT be annotated using GO terms." + +#### Added +- [cell death](http://purl.obolibrary.org/obo/GO_0008219) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "This term should not be used for direct annotation, it is currently kept in GO as a placeholder for describing cell death phenotypes in uPHENO. When information is provided on a programmed cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'). Unintentional cell death, i.e. cell death caused by injury, ageing, or cell phenotypes observed as a result of a pathological mutation in an essential gene should NOT be annotated using GO terms." + + +### cell motility `http://purl.obolibrary.org/obo/GO_0048870` +#### Removed +- [cell motility](http://purl.obolibrary.org/obo/GO_0048870) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [prokaryote_subset](http://purl.obolibrary.org/obo/go#prokaryote_subset) + +#### Added +- [cell motility](http://purl.obolibrary.org/obo/GO_0048870) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_prokaryote](http://purl.obolibrary.org/obo/go#goslim_prokaryote) + + +### cell of skeletal muscle `http://purl.obolibrary.org/obo/CL_0000188` + +#### Added +- [cell of skeletal muscle](http://purl.obolibrary.org/obo/CL_0000188) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### cell periphery `http://purl.obolibrary.org/obo/GO_0071944` +#### Removed +- [cell periphery](http://purl.obolibrary.org/obo/GO_0071944) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:pdt" + +#### Added +- [cell periphery](http://purl.obolibrary.org/obo/GO_0071944) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:pdt" + + +### cell projection `http://purl.obolibrary.org/obo/GO_0042995` +#### Removed +- [cell projection](http://purl.obolibrary.org/obo/GO_0042995) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [prokaryote_subset](http://purl.obolibrary.org/obo/go#prokaryote_subset) + +#### Added +- [cell projection](http://purl.obolibrary.org/obo/GO_0042995) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_prokaryote](http://purl.obolibrary.org/obo/go#goslim_prokaryote) + + +### cell projection organization `http://purl.obolibrary.org/obo/GO_0030030` +#### Removed +- [cell projection organization](http://purl.obolibrary.org/obo/GO_0030030) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [prokaryote_subset](http://purl.obolibrary.org/obo/go#prokaryote_subset) + +#### Added +- [cell projection organization](http://purl.obolibrary.org/obo/GO_0030030) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_prokaryote](http://purl.obolibrary.org/obo/go#goslim_prokaryote) + + +### cellular anatomical entity `http://purl.obolibrary.org/obo/GO_0110165` + +#### Added +- [cellular anatomical entity](http://purl.obolibrary.org/obo/GO_0110165) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) "https://github.com/geneontology/go-ontology/issues/26424"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + + +### cellular modified amino acid metabolic process `http://purl.obolibrary.org/obo/GO_0006575` +#### Removed +- [cellular modified amino acid metabolic process](http://purl.obolibrary.org/obo/GO_0006575) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [prokaryote_subset](http://purl.obolibrary.org/obo/go#prokaryote_subset) + +#### Added +- [cellular modified amino acid metabolic process](http://purl.obolibrary.org/obo/GO_0006575) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_prokaryote](http://purl.obolibrary.org/obo/go#goslim_prokaryote) + + +### cellular nitrogen compound metabolic process `http://purl.obolibrary.org/obo/GO_0034641` + +#### Added +- [cellular nitrogen compound metabolic process](http://purl.obolibrary.org/obo/GO_0034641) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) "https://github.com/geneontology/go-ontology/issues/26424"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + +- [cellular nitrogen compound metabolic process](http://purl.obolibrary.org/obo/GO_0034641) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [gocheck_do_not_annotate](http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate) + + +### cellular response to inorganic substance `http://purl.obolibrary.org/obo/GO_0071241` +#### Removed +- [cellular response to inorganic substance](http://purl.obolibrary.org/obo/GO_0071241) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [cellular response to inorganic substance](http://purl.obolibrary.org/obo/GO_0071241) [creation date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2009-12-03T02:35:49Z" + +- [cellular response to inorganic substance](http://purl.obolibrary.org/obo/GO_0071241) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0071241" + +- [cellular response to inorganic substance](http://purl.obolibrary.org/obo/GO_0071241) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- [cellular response to inorganic substance](http://purl.obolibrary.org/obo/GO_0071241) [created by](http://www.geneontology.org/formats/oboInOwl#created_by) "mah" + +- [cellular response to inorganic substance](http://purl.obolibrary.org/obo/GO_0071241) [label](http://www.w3.org/2000/01/rdf-schema#label) "cellular response to inorganic substance" + +- Class: [cellular response to inorganic substance](http://purl.obolibrary.org/obo/GO_0071241) + +- [cellular response to inorganic substance](http://purl.obolibrary.org/obo/GO_0071241) SubClassOf [response to inorganic substance](http://purl.obolibrary.org/obo/GO_0010035) + +- [cellular response to inorganic substance](http://purl.obolibrary.org/obo/GO_0071241) SubClassOf [cellular response to chemical stimulus](http://purl.obolibrary.org/obo/GO_0070887) + + + +### cellular response to nitric oxide `http://purl.obolibrary.org/obo/GO_0071732` +#### Removed +- [cellular response to nitric oxide](http://purl.obolibrary.org/obo/GO_0071732) [creation date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2010-03-17T04:12:52Z" + +- [cellular response to nitric oxide](http://purl.obolibrary.org/obo/GO_0071732) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [cellular response to nitric oxide](http://purl.obolibrary.org/obo/GO_0071732) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0071732" + +- [cellular response to nitric oxide](http://purl.obolibrary.org/obo/GO_0071732) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitric oxide stimulus." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:yaf" + +- [cellular response to nitric oxide](http://purl.obolibrary.org/obo/GO_0071732) [created by](http://www.geneontology.org/formats/oboInOwl#created_by) "mah" + +- [cellular response to nitric oxide](http://purl.obolibrary.org/obo/GO_0071732) [label](http://www.w3.org/2000/01/rdf-schema#label) "cellular response to nitric oxide" + +- Class: [cellular response to nitric oxide](http://purl.obolibrary.org/obo/GO_0071732) + +- [cellular response to nitric oxide](http://purl.obolibrary.org/obo/GO_0071732) EquivalentTo [cellular response to chemical stimulus](http://purl.obolibrary.org/obo/GO_0070887) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [CHEBI_16480](http://purl.obolibrary.org/obo/CHEBI_16480)) + +- [cellular response to nitric oxide](http://purl.obolibrary.org/obo/GO_0071732) SubClassOf [response to nitric oxide](http://purl.obolibrary.org/obo/GO_0071731) + +- [cellular response to nitric oxide](http://purl.obolibrary.org/obo/GO_0071732) SubClassOf [cellular response to inorganic substance](http://purl.obolibrary.org/obo/GO_0071241) + + + +### cellular_component `http://purl.obolibrary.org/obo/GO_0005575` +#### Removed +- [cellular_component](http://purl.obolibrary.org/obo/GO_0005575) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex)." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:pdt" + +#### Added +- [cellular_component](http://purl.obolibrary.org/obo/GO_0005575) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex)." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:pdt" + + +### central memory CD4-positive, alpha-beta T cell `http://purl.obolibrary.org/obo/CL_0000904` + +#### Added +- [central memory CD4-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000904) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### central memory CD8-positive, alpha-beta T cell `http://purl.obolibrary.org/obo/CL_0000907` + +#### Added +- [central memory CD8-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000907) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### central nervous system `http://purl.obolibrary.org/obo/UBERON_0001017` +#### Removed +- [central nervous system](http://purl.obolibrary.org/obo/UBERON_0001017) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005094" + +- [central nervous system](http://purl.obolibrary.org/obo/UBERON_0001017) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "systema nervosum centrale" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:55675" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [central nervous system](http://purl.obolibrary.org/obo/UBERON_0001017) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005094" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + +- [central nervous system](http://purl.obolibrary.org/obo/UBERON_0001017) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [human_reference_atlas](http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas) + +- [central nervous system](http://purl.obolibrary.org/obo/UBERON_0001017) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606) + +- [central nervous system](http://purl.obolibrary.org/obo/UBERON_0001017) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "systema nervosum centrale" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:55675" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### central nervous system macrophage `http://purl.obolibrary.org/obo/CL_0000878` + +#### Added +- [central nervous system macrophage](http://purl.obolibrary.org/obo/CL_0000878) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### central sulcus `http://purl.obolibrary.org/obo/UBERON_0002916` +#### Removed +- [central sulcus](http://purl.obolibrary.org/obo/UBERON_0002916) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sulcus centralis cerebri" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Central_sulcus" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BIRNLEX:4035" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [central sulcus](http://purl.obolibrary.org/obo/UBERON_0002916) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sulcus centralis cerebri" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Central_sulcus" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BIRNLEX:4035" + + +### central tendon of diaphragm `http://purl.obolibrary.org/obo/UBERON_0006670` +#### Removed +- [central tendon of diaphragm](http://purl.obolibrary.org/obo/UBERON_0006670) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "centrum tendineum diaphragmatis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:58279" + +#### Added +- [central tendon of diaphragm](http://purl.obolibrary.org/obo/UBERON_0006670) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "centrum tendineum diaphragmatis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:58279" + + +### centrilobular region hepatocyte `http://purl.obolibrary.org/obo/CL_0019029` + +#### Added +- [centrilobular region hepatocyte](http://purl.obolibrary.org/obo/CL_0019029) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### centroblast `http://purl.obolibrary.org/obo/CL_0009112` + +#### Added +- [centroblast](http://purl.obolibrary.org/obo/CL_0009112) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### centrocyte `http://purl.obolibrary.org/obo/CL_0009111` + +#### Added +- [centrocyte](http://purl.obolibrary.org/obo/CL_0009111) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### cerebellar Golgi cell `http://purl.obolibrary.org/obo/CL_0000119` + +#### Added +- [cerebellar Golgi cell](http://purl.obolibrary.org/obo/CL_0000119) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### cerebellar cortex `http://purl.obolibrary.org/obo/UBERON_0002129` +#### Removed +- [cerebellar cortex](http://purl.obolibrary.org/obo/UBERON_0002129) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cortex cerebelli" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:647" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [cerebellar cortex](http://purl.obolibrary.org/obo/UBERON_0002129) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cortex cerebelli" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:647" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### cerebellar granule cell `http://purl.obolibrary.org/obo/CL_0001031` + +#### Added +- [cerebellar granule cell](http://purl.obolibrary.org/obo/CL_0001031) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### cerebellum `http://purl.obolibrary.org/obo/UBERON_0002037` +#### Removed +- [cerebellum](http://purl.obolibrary.org/obo/UBERON_0002037) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "parencephalon" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:643" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [cerebellum](http://purl.obolibrary.org/obo/UBERON_0002037) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "corpus cerebelli" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:643" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [cerebellum](http://purl.obolibrary.org/obo/UBERON_0002037) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "parencephalon" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:643" + +- [cerebellum](http://purl.obolibrary.org/obo/UBERON_0002037) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "corpus cerebelli" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:643" + + +### cerebellum fissure `http://purl.obolibrary.org/obo/UBERON_0003980` +#### Removed +- [cerebellum fissure](http://purl.obolibrary.org/obo/UBERON_0003980) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "fissurae cerebelli" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:77789" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [cerebellum fissure](http://purl.obolibrary.org/obo/UBERON_0003980) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "fissurae cerebelli" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:77789" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### cerebral cortex `http://purl.obolibrary.org/obo/UBERON_0000956` +#### Removed +- [cerebral cortex](http://purl.obolibrary.org/obo/UBERON_0000956) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cortex cerebralis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:39" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [cerebral cortex](http://purl.obolibrary.org/obo/UBERON_0000956) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cortex cerebri" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Cerebral_cortex" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [cerebral cortex](http://purl.obolibrary.org/obo/UBERON_0000956) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cortex cerebralis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:39" + +- [cerebral cortex](http://purl.obolibrary.org/obo/UBERON_0000956) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cortex cerebri" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Cerebral_cortex" + + +### cerebral cortex GABAergic interneuron `http://purl.obolibrary.org/obo/CL_0010011` + +#### Added +- [cerebral cortex GABAergic interneuron](http://purl.obolibrary.org/obo/CL_0010011) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### cerebral cortex endothelial cell `http://purl.obolibrary.org/obo/CL_1001602` + +#### Added +- [cerebral cortex endothelial cell](http://purl.obolibrary.org/obo/CL_1001602) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### cerebral cortex neuron `http://purl.obolibrary.org/obo/CL_0010012` + +#### Added +- [cerebral cortex neuron](http://purl.obolibrary.org/obo/CL_0010012) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### cerebral hemisphere `http://purl.obolibrary.org/obo/UBERON_0001869` +#### Removed +- [cerebral hemisphere](http://purl.obolibrary.org/obo/UBERON_0001869) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "hemispherium cerebri" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Cerebral_hemisphere" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [cerebral hemisphere](http://purl.obolibrary.org/obo/UBERON_0001869) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus medialis amygdalae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:241" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [cerebral hemisphere](http://purl.obolibrary.org/obo/UBERON_0001869) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus amygdaloideus medialis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:241" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [cerebral hemisphere](http://purl.obolibrary.org/obo/UBERON_0001869) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus medialis amygdalae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:241" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [cerebral hemisphere](http://purl.obolibrary.org/obo/UBERON_0001869) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus amygdaloideus medialis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:241" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [cerebral hemisphere](http://purl.obolibrary.org/obo/UBERON_0001869) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "hemispherium cerebri" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Cerebral_hemisphere" + + +### cerebral hemisphere white matter `http://purl.obolibrary.org/obo/UBERON_0002437` +#### Removed +- [cerebral hemisphere white matter](http://purl.obolibrary.org/obo/UBERON_0002437) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "substantia medullaris cerebri" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:189" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [cerebral hemisphere white matter](http://purl.obolibrary.org/obo/UBERON_0002437) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "substantia medullaris cerebri" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:189" + + +### cerebral vein `http://purl.obolibrary.org/obo/UBERON_0001663` +#### Removed +- [cerebral vein](http://purl.obolibrary.org/obo/UBERON_0001663) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "venae cerebri" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Cerebral_veins" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [cerebral vein](http://purl.obolibrary.org/obo/UBERON_0001663) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "venae encephali" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Cerebral_veins" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [cerebral vein](http://purl.obolibrary.org/obo/UBERON_0001663) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "venae encephali" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Cerebral_veins" + +- [cerebral vein](http://purl.obolibrary.org/obo/UBERON_0001663) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "venae cerebri" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Cerebral_veins" + + +### cervical rib `http://purl.obolibrary.org/obo/UBERON_0018144` +#### Removed +- [cervical rib](http://purl.obolibrary.org/obo/UBERON_0018144) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D057070" + +#### Added +- [cervical rib](http://purl.obolibrary.org/obo/UBERON_0018144) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D057070" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [author_id](https://w3id.org/sssom/author_id) [0000-0001-9439-5346](https://orcid.org/0000-0001-9439-5346) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### cervical spinal cord `http://purl.obolibrary.org/obo/UBERON_0002726` +#### Removed +- [cervical spinal cord](http://purl.obolibrary.org/obo/UBERON_0002726) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "segmenta cervicalia medullae spinalis [1-8" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:71166" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [cervical spinal cord](http://purl.obolibrary.org/obo/UBERON_0002726) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pars cervicalis medullae spinalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:71166" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [cervical spinal cord](http://purl.obolibrary.org/obo/UBERON_0002726) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pars cervicalis medullae spinalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:71166" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [cervical spinal cord](http://purl.obolibrary.org/obo/UBERON_0002726) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D066193" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [LexicalMatching](https://w3id.org/semapv/vocab/LexicalMatching) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + +- [cervical spinal cord](http://purl.obolibrary.org/obo/UBERON_0002726) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "segmenta cervicalia medullae spinalis [1-8" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:71166" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### cervical spinal cord ventral horn `http://purl.obolibrary.org/obo/UBERON_0014621` + +#### Added +- [cervical spinal cord ventral horn](http://purl.obolibrary.org/obo/UBERON_0014621) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D066151" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [LexicalMatching](https://w3id.org/semapv/vocab/LexicalMatching) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### cervical vertebra `http://purl.obolibrary.org/obo/UBERON_0002413` +#### Removed +- [cervical vertebra](http://purl.obolibrary.org/obo/UBERON_0002413) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vertebrae cervicales" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Cervical_vertebrae" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [cervical vertebra](http://purl.obolibrary.org/obo/UBERON_0002413) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vertebrae cervicales" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Cervical_vertebrae" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### chandelier pvalb GABAergic cortical interneuron `http://purl.obolibrary.org/obo/CL_4023036` + +#### Added +- [chandelier pvalb GABAergic cortical interneuron](http://purl.obolibrary.org/obo/CL_4023036) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### chemosensory organ `http://purl.obolibrary.org/obo/UBERON_0000005` +#### Removed +- [chemosensory organ](http://purl.obolibrary.org/obo/UBERON_0000005) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005157" + +#### Added +- [chemosensory organ](http://purl.obolibrary.org/obo/UBERON_0000005) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005157" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### chest `http://purl.obolibrary.org/obo/UBERON_0001443` +#### Removed +- [chest](http://purl.obolibrary.org/obo/UBERON_0001443) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pectus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:24816" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [chest](http://purl.obolibrary.org/obo/UBERON_0001443) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "thorax" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:9576" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Chest" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [chest](http://purl.obolibrary.org/obo/UBERON_0001443) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pectus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:24816" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [chest](http://purl.obolibrary.org/obo/UBERON_0001443) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "thorax" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:9576" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Chest" + + +### chest wall `http://purl.obolibrary.org/obo/UBERON_0016435` + +#### Added +- [chest wall](http://purl.obolibrary.org/obo/UBERON_0016435) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D035441" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [LexicalMatching](https://w3id.org/semapv/vocab/LexicalMatching) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### cholangiocyte `http://purl.obolibrary.org/obo/CL_1000488` + +#### Added +- [cholangiocyte](http://purl.obolibrary.org/obo/CL_1000488) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### chondrocyte `http://purl.obolibrary.org/obo/CL_0000138` + +#### Added +- [chondrocyte](http://purl.obolibrary.org/obo/CL_0000138) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### chordate pharyngeal muscle `http://purl.obolibrary.org/obo/UBERON_0000933` +#### Removed +- [chordate pharyngeal muscle](http://purl.obolibrary.org/obo/UBERON_0000933) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "musculi pharyngis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Pharyngeal_muscles" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [chordate pharyngeal muscle](http://purl.obolibrary.org/obo/UBERON_0000933) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tunica muscularis pharyngis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Pharyngeal_muscles" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [chordate pharyngeal muscle](http://purl.obolibrary.org/obo/UBERON_0000933) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tunica muscularis pharyngis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Pharyngeal_muscles" + +- [chordate pharyngeal muscle](http://purl.obolibrary.org/obo/UBERON_0000933) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "musculi pharyngis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Pharyngeal_muscles" + + +### chordotonal organ `http://purl.obolibrary.org/obo/UBERON_0001038` +#### Removed +- [chordotonal organ](http://purl.obolibrary.org/obo/UBERON_0001038) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005215" + +#### Added +- [chordotonal organ](http://purl.obolibrary.org/obo/UBERON_0001038) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005215" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### chorionic plate `http://purl.obolibrary.org/obo/UBERON_0004027` + +#### Added +- [chorionic plate](http://purl.obolibrary.org/obo/UBERON_0004027) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [placental disc](http://purl.obolibrary.org/obo/UBERON_8600038) + +- [chorionic plate](http://purl.obolibrary.org/obo/UBERON_0004027) SubClassOf [reproductive structure](http://purl.obolibrary.org/obo/UBERON_0005156) + + +### chorionic plate blood vessel `http://purl.obolibrary.org/obo/UBERON_8600021` +#### Removed +- [chorionic plate blood vessel](http://purl.obolibrary.org/obo/UBERON_8600021) SubClassOf [blood vessel](http://purl.obolibrary.org/obo/UBERON_0001981) + +#### Added +- [chorionic plate blood vessel](http://purl.obolibrary.org/obo/UBERON_8600021) SubClassOf [placenta blood vessel](http://purl.obolibrary.org/obo/UBERON_0022358) + + +### chorionic trophoblast cell `http://purl.obolibrary.org/obo/CL_0011101` + +#### Added +- [chorionic trophoblast cell](http://purl.obolibrary.org/obo/CL_0011101) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### chorionic villous mesenchyme `http://purl.obolibrary.org/obo/UBERON_8600039` + +#### Added +- [chorionic villous mesenchyme](http://purl.obolibrary.org/obo/UBERON_8600039) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A mesenchyme that is part of a chorionic villus." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "doi:10.1007/978-3-030-84725-8" + +- [chorionic villous mesenchyme](http://purl.obolibrary.org/obo/UBERON_8600039) [id](http://www.geneontology.org/formats/oboInOwl#id) "UBERON:8600039" + +- [chorionic villous mesenchyme](http://purl.obolibrary.org/obo/UBERON_8600039) [label](http://www.w3.org/2000/01/rdf-schema#label) "chorionic villous mesenchyme" + +- [chorionic villous mesenchyme](http://purl.obolibrary.org/obo/UBERON_8600039) [date](http://purl.org/dc/terms/date) "2024-01-16T18:13:12Z"^^[dateTime](http://www.w3.org/2001/XMLSchema#dateTime) + +- [chorionic villous mesenchyme](http://purl.obolibrary.org/obo/UBERON_8600039) [contributor](http://purl.org/dc/terms/contributor) [0000-0001-6677-8489](https://orcid.org/0000-0001-6677-8489) + +- [chorionic villous mesenchyme](http://purl.obolibrary.org/obo/UBERON_8600039) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "uberon" + +- Class: [chorionic villous mesenchyme](http://purl.obolibrary.org/obo/UBERON_8600039) + +- [chorionic villous mesenchyme](http://purl.obolibrary.org/obo/UBERON_8600039) EquivalentTo [mesenchyme](http://purl.obolibrary.org/obo/UBERON_0003104) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [chorionic villus](http://purl.obolibrary.org/obo/UBERON_0007106)) + +- [chorionic villous mesenchyme](http://purl.obolibrary.org/obo/UBERON_8600039) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [chorionic villus](http://purl.obolibrary.org/obo/UBERON_0007106) + +- [chorionic villous mesenchyme](http://purl.obolibrary.org/obo/UBERON_8600039) SubClassOf [embryonic tissue](http://purl.obolibrary.org/obo/UBERON_0005291) + +- [chorionic villous mesenchyme](http://purl.obolibrary.org/obo/UBERON_8600039) SubClassOf [chorionic mesenchyme](http://purl.obolibrary.org/obo/UBERON_0003265) + +- [chorionic villous mesenchyme](http://purl.obolibrary.org/obo/UBERON_8600039) SubClassOf [embryonic structure](http://purl.obolibrary.org/obo/UBERON_0002050) + + +### choroid plexus `http://purl.obolibrary.org/obo/UBERON_0001886` +#### Removed +- [choroid plexus](http://purl.obolibrary.org/obo/UBERON_0001886) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "plexus choroideus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:61934" + +- [choroid plexus](http://purl.obolibrary.org/obo/UBERON_0001886) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "plexus choroideus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Choroid_plexus" + +#### Added +- [choroid plexus](http://purl.obolibrary.org/obo/UBERON_0001886) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "plexus choroideus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:61934" + +- [choroid plexus](http://purl.obolibrary.org/obo/UBERON_0001886) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "plexus choroideus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Choroid_plexus" + + +### choroid plexus epithelial cell `http://purl.obolibrary.org/obo/CL_0000706` + +#### Added +- [choroid plexus epithelial cell](http://purl.obolibrary.org/obo/CL_0000706) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### choroid plexus epithelium `http://purl.obolibrary.org/obo/UBERON_0003911` +#### Removed +- [choroid plexus epithelium](http://purl.obolibrary.org/obo/UBERON_0003911) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0006008" + - [contributor](http://purl.org/dc/terms/contributor) "https://orcid.org/0000-0003-4423-4370" + +#### Added +- [choroid plexus epithelium](http://purl.obolibrary.org/obo/UBERON_0003911) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0006008" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + - [author_id](https://w3id.org/sssom/author_id) [0000-0003-4423-4370](https://orcid.org/0000-0003-4423-4370) + + +### choroidal blood vessel `http://purl.obolibrary.org/obo/UBERON_0002443` +#### Removed +- [choroidal blood vessel](http://purl.obolibrary.org/obo/UBERON_0002443) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "vasa sanguinea choroideae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:76550" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [choroidal blood vessel](http://purl.obolibrary.org/obo/UBERON_0002443) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "vasa sanguinea choroideae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:76550" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### chromaffin cell `http://purl.obolibrary.org/obo/CL_0000166` + +#### Added +- [chromaffin cell](http://purl.obolibrary.org/obo/CL_0000166) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### chromosome `http://purl.obolibrary.org/obo/GO_0005694` +#### Removed +- [chromosome](http://purl.obolibrary.org/obo/GO_0005694) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [prokaryote_subset](http://purl.obolibrary.org/obo/go#prokaryote_subset) + +#### Added +- [chromosome](http://purl.obolibrary.org/obo/GO_0005694) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_prokaryote](http://purl.obolibrary.org/obo/go#goslim_prokaryote) + + +### chromosome segregation `http://purl.obolibrary.org/obo/GO_0007059` +#### Removed +- [chromosome segregation](http://purl.obolibrary.org/obo/GO_0007059) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [prokaryote_subset](http://purl.obolibrary.org/obo/go#prokaryote_subset) + +#### Added +- [chromosome segregation](http://purl.obolibrary.org/obo/GO_0007059) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_prokaryote](http://purl.obolibrary.org/obo/go#goslim_prokaryote) + + +### ciliary body `http://purl.obolibrary.org/obo/UBERON_0001775` +#### Removed +- [ciliary body](http://purl.obolibrary.org/obo/UBERON_0001775) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "corpus ciliare" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Ciliary_body" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [ciliary body](http://purl.obolibrary.org/obo/UBERON_0001775) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "corpus ciliare" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Ciliary_body" + + +### ciliary muscle `http://purl.obolibrary.org/obo/UBERON_0001605` +#### Removed +- [ciliary muscle](http://purl.obolibrary.org/obo/UBERON_0001605) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "musculus ciliaris" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Ciliary_muscle" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [ciliary muscle](http://purl.obolibrary.org/obo/UBERON_0001605) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "musculus ciliaris" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Ciliary_muscle" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### ciliary muscle cell `http://purl.obolibrary.org/obo/CL_1000443` + +#### Added +- [ciliary muscle cell](http://purl.obolibrary.org/obo/CL_1000443) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### ciliary processes `http://purl.obolibrary.org/obo/UBERON_0010427` +#### Removed +- [ciliary processes](http://purl.obolibrary.org/obo/UBERON_0010427) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "processus ciliares" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [ciliary processes](http://purl.obolibrary.org/obo/UBERON_0010427) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "processus ciliares" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Ciliary_processes" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [ciliary processes](http://purl.obolibrary.org/obo/UBERON_0010427) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "processus ciliares" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [ciliary processes](http://purl.obolibrary.org/obo/UBERON_0010427) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "processus ciliares" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Ciliary_processes" + + +### ciliated cell `http://purl.obolibrary.org/obo/CL_0000064` + +#### Added +- [ciliated cell](http://purl.obolibrary.org/obo/CL_0000064) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### ciliated cell of the bronchus `http://purl.obolibrary.org/obo/CL_0002332` + +#### Added +- [ciliated cell of the bronchus](http://purl.obolibrary.org/obo/CL_0002332) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### ciliated columnar cell of tracheobronchial tree `http://purl.obolibrary.org/obo/CL_0002145` + +#### Added +- [ciliated columnar cell of tracheobronchial tree](http://purl.obolibrary.org/obo/CL_0002145) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### ciliated epithelial cell `http://purl.obolibrary.org/obo/CL_0000067` + +#### Added +- [ciliated epithelial cell](http://purl.obolibrary.org/obo/CL_0000067) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### circle of Willis `http://purl.obolibrary.org/obo/UBERON_0003709` +#### Removed +- [circle of Willis](http://purl.obolibrary.org/obo/UBERON_0003709) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "circulus arteriosus cerebri" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Circle_of_Willis" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [circle of Willis](http://purl.obolibrary.org/obo/UBERON_0003709) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "circulus arteriosus cerebri" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Circle_of_Willis" + + +### circulatory system `http://purl.obolibrary.org/obo/UBERON_0001009` +#### Removed +- [circulatory system](http://purl.obolibrary.org/obo/UBERON_0001009) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "systema cardiovasculare" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Circulatory_system" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [circulatory system](http://purl.obolibrary.org/obo/UBERON_0001009) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D002319" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [LexicalMatching](https://w3id.org/semapv/vocab/LexicalMatching) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + +- [circulatory system](http://purl.obolibrary.org/obo/UBERON_0001009) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "systema cardiovasculare" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Circulatory_system" + + +### circumventricular organ `http://purl.obolibrary.org/obo/UBERON_0005408` +#### Removed +- [circumventricular organ](http://purl.obolibrary.org/obo/UBERON_0005408) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D066280" + +- [circumventricular organ](http://purl.obolibrary.org/obo/UBERON_0005408) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0006267" + - [contributor](http://purl.org/dc/terms/contributor) "https://orcid.org/0000-0003-4423-4370" + +#### Added +- [circumventricular organ](http://purl.obolibrary.org/obo/UBERON_0005408) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D066280" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [author_id](https://w3id.org/sssom/author_id) [0000-0001-9439-5346](https://orcid.org/0000-0001-9439-5346) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + +- [circumventricular organ](http://purl.obolibrary.org/obo/UBERON_0005408) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0006267" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + - [author_id](https://w3id.org/sssom/author_id) [0000-0003-4423-4370](https://orcid.org/0000-0003-4423-4370) + + +### class switched memory B cell `http://purl.obolibrary.org/obo/CL_0000972` + +#### Added +- [class switched memory B cell](http://purl.obolibrary.org/obo/CL_0000972) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### classical monocyte `http://purl.obolibrary.org/obo/CL_0000860` + +#### Added +- [classical monocyte](http://purl.obolibrary.org/obo/CL_0000860) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### cloacal membrane `http://purl.obolibrary.org/obo/UBERON_0006217` +#### Removed +- [cloacal membrane](http://purl.obolibrary.org/obo/UBERON_0006217) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "membrana cloacalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Cloacal_membrane" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [cloacal membrane](http://purl.obolibrary.org/obo/UBERON_0006217) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "membrana cloacalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Cloacal_membrane" + + +### club cell `http://purl.obolibrary.org/obo/CL_0000158` + +#### Added +- [club cell](http://purl.obolibrary.org/obo/CL_0000158) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### cochlear duct of membranous labyrinth `http://purl.obolibrary.org/obo/UBERON_0001855` +#### Removed +- [cochlear duct of membranous labyrinth](http://purl.obolibrary.org/obo/UBERON_0001855) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ductus cochlearis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0001692" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Cochlear_duct" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [cochlear duct of membranous labyrinth](http://purl.obolibrary.org/obo/UBERON_0001855) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ductus cochlearis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0001692" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Cochlear_duct" + + +### cochlear ganglion `http://purl.obolibrary.org/obo/UBERON_0000395` +#### Removed +- [cochlear ganglion](http://purl.obolibrary.org/obo/UBERON_0000395) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ganglion spirale" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Spiral_ganglion" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [cochlear ganglion](http://purl.obolibrary.org/obo/UBERON_0000395) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ganglion spirale" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Spiral_ganglion" + + +### cochlear modiolus `http://purl.obolibrary.org/obo/UBERON_0006723` +#### Removed +- [cochlear modiolus](http://purl.obolibrary.org/obo/UBERON_0006723) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "modiolus cochleae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:61278" + +#### Added +- [cochlear modiolus](http://purl.obolibrary.org/obo/UBERON_0006723) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "modiolus cochleae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:61278" + + +### cochlear nuclear complex `http://purl.obolibrary.org/obo/UBERON_0002610` +#### Removed +- [cochlear nuclear complex](http://purl.obolibrary.org/obo/UBERON_0002610) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nuclei cochleares" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Cochlear_nuclei" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [cochlear nuclear complex](http://purl.obolibrary.org/obo/UBERON_0002610) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nuclei cochleares" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Cochlear_nuclei" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### coelemic cavity lumen `http://purl.obolibrary.org/obo/UBERON_0002323` +#### Removed +- [coelemic cavity lumen](http://purl.obolibrary.org/obo/UBERON_0002323) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005060" + +#### Added +- [coelemic cavity lumen](http://purl.obolibrary.org/obo/UBERON_0002323) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005060" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### collagen fibril binding `http://purl.obolibrary.org/obo/GO_0098633` +#### Removed +- [collagen fibril binding](http://purl.obolibrary.org/obo/GO_0098633) SubClassOf [binding](http://purl.obolibrary.org/obo/GO_0005488) + +#### Added +- [collagen fibril binding](http://purl.obolibrary.org/obo/GO_0098633) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) "https://github.com/geneontology/go-ontology/issues/21211"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + +- [collagen fibril binding](http://purl.obolibrary.org/obo/GO_0098633) SubClassOf [extracellular matrix binding](http://purl.obolibrary.org/obo/GO_0050840) + + +### collagen secreting cell `http://purl.obolibrary.org/obo/CL_0000667` + +#### Added +- [collagen secreting cell](http://purl.obolibrary.org/obo/CL_0000667) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### collecting duct of renal tubule `http://purl.obolibrary.org/obo/UBERON_0001232` +#### Removed +- [collecting duct of renal tubule](http://purl.obolibrary.org/obo/UBERON_0001232) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tubulus renalis arcuatus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Connecting_tubule" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [collecting duct of renal tubule](http://purl.obolibrary.org/obo/UBERON_0001232) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tubulus renalis arcuatus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Connecting_tubule" + + +### collection of hairs `http://purl.obolibrary.org/obo/UBERON_0010164` +#### Removed +- [collection of hairs](http://purl.obolibrary.org/obo/UBERON_0010164) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pili" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [collection of hairs](http://purl.obolibrary.org/obo/UBERON_0010164) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pili" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### colon epithelial cell `http://purl.obolibrary.org/obo/CL_0011108` + +#### Added +- [colon epithelial cell](http://purl.obolibrary.org/obo/CL_0011108) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### colon goblet cell `http://purl.obolibrary.org/obo/CL_0009039` + +#### Added +- [colon goblet cell](http://purl.obolibrary.org/obo/CL_0009039) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### colon macrophage `http://purl.obolibrary.org/obo/CL_0009038` + +#### Added +- [colon macrophage](http://purl.obolibrary.org/obo/CL_0009038) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### columnar/cuboidal epithelial cell `http://purl.obolibrary.org/obo/CL_0000075` + +#### Added +- [columnar/cuboidal epithelial cell](http://purl.obolibrary.org/obo/CL_0000075) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### common bile duct `http://purl.obolibrary.org/obo/UBERON_0001174` +#### Removed +- [common bile duct](http://purl.obolibrary.org/obo/UBERON_0001174) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ductus choledochus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Common_bile_duct" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [common bile duct](http://purl.obolibrary.org/obo/UBERON_0001174) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ductus choledochus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Common_bile_duct" + + +### common carotid artery plus branches `http://purl.obolibrary.org/obo/UBERON_0001530` +#### Removed +- [common carotid artery plus branches](http://purl.obolibrary.org/obo/UBERON_0001530) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "a. carotis communis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Common_carotid_artery" + +#### Added +- [common carotid artery plus branches](http://purl.obolibrary.org/obo/UBERON_0001530) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "a. carotis communis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Common_carotid_artery" + + +### common dendritic progenitor `http://purl.obolibrary.org/obo/CL_0001029` + +#### Added +- [common dendritic progenitor](http://purl.obolibrary.org/obo/CL_0001029) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### common hepatic artery `http://purl.obolibrary.org/obo/UBERON_0005436` +#### Removed +- [common hepatic artery](http://purl.obolibrary.org/obo/UBERON_0005436) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria hepatica communis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Common_hepatic_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [common hepatic artery](http://purl.obolibrary.org/obo/UBERON_0005436) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria hepatica communis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Common_hepatic_artery" + + +### common hepatic duct `http://purl.obolibrary.org/obo/UBERON_0001175` +#### Removed +- [common hepatic duct](http://purl.obolibrary.org/obo/UBERON_0001175) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ductus hepaticus communis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Common_hepatic_duct" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [common hepatic duct](http://purl.obolibrary.org/obo/UBERON_0001175) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ductus hepaticus communis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Common_hepatic_duct" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### common iliac artery `http://purl.obolibrary.org/obo/UBERON_0001191` +#### Removed +- [common iliac artery](http://purl.obolibrary.org/obo/UBERON_0001191) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria iliaca communis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Common_iliac_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [common iliac artery](http://purl.obolibrary.org/obo/UBERON_0001191) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria iliaca communis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Common_iliac_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### common iliac vein `http://purl.obolibrary.org/obo/UBERON_0001139` +#### Removed +- [common iliac vein](http://purl.obolibrary.org/obo/UBERON_0001139) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vena iliaca communis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Common_iliac_vein" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [common iliac vein](http://purl.obolibrary.org/obo/UBERON_0001139) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vena iliaca communis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Common_iliac_vein" + + +### common lymphoid progenitor `http://purl.obolibrary.org/obo/CL_0000051` + +#### Added +- [common lymphoid progenitor](http://purl.obolibrary.org/obo/CL_0000051) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### common myeloid progenitor `http://purl.obolibrary.org/obo/CL_0000049` + +#### Added +- [common myeloid progenitor](http://purl.obolibrary.org/obo/CL_0000049) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### compact bone tissue `http://purl.obolibrary.org/obo/UBERON_0001439` +#### Removed +- [compact bone tissue](http://purl.obolibrary.org/obo/UBERON_0001439) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "substantia compacta" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:24018" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [compact bone tissue](http://purl.obolibrary.org/obo/UBERON_0001439) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "substantia corticalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:24018" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [compact bone tissue](http://purl.obolibrary.org/obo/UBERON_0001439) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "substantia compacta" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:24018" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [compact bone tissue](http://purl.obolibrary.org/obo/UBERON_0001439) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D000071538" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [LexicalMatching](https://w3id.org/semapv/vocab/LexicalMatching) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + +- [compact bone tissue](http://purl.obolibrary.org/obo/UBERON_0001439) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "substantia corticalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:24018" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### compound eye `http://purl.obolibrary.org/obo/UBERON_0000018` +#### Removed +- [compound eye](http://purl.obolibrary.org/obo/UBERON_0000018) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00004508" + +- [compound eye](http://purl.obolibrary.org/obo/UBERON_0000018) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IDOMAL:0002421" + - [contributor](http://purl.org/dc/terms/contributor) "https://orcid.org/0000-0003-4423-4370" + +#### Added +- [compound eye](http://purl.obolibrary.org/obo/UBERON_0000018) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00004508" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + +- [compound eye](http://purl.obolibrary.org/obo/UBERON_0000018) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IDOMAL:0002421" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + - [author_id](https://w3id.org/sssom/author_id) [0000-0003-4423-4370](https://orcid.org/0000-0003-4423-4370) + + +### conducting system of heart `http://purl.obolibrary.org/obo/UBERON_0002350` +#### Removed +- [conducting system of heart](http://purl.obolibrary.org/obo/UBERON_0002350) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "complexus stimulans cordis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:9476" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [conducting system of heart](http://purl.obolibrary.org/obo/UBERON_0002350) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "systema conducente cordis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:9476" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [conducting system of heart](http://purl.obolibrary.org/obo/UBERON_0002350) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "systema conducente cordis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:9476" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [conducting system of heart](http://purl.obolibrary.org/obo/UBERON_0002350) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "complexus stimulans cordis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:9476" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### conjunctiva `http://purl.obolibrary.org/obo/UBERON_0001811` +#### Removed +- [conjunctiva](http://purl.obolibrary.org/obo/UBERON_0001811) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica conjunctiva" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [conjunctiva](http://purl.obolibrary.org/obo/UBERON_0001811) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica conjunctiva" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### conjunctival epithelial cell `http://purl.obolibrary.org/obo/CL_1000432` + +#### Added +- [conjunctival epithelial cell](http://purl.obolibrary.org/obo/CL_1000432) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### conjunctival vasculature `http://purl.obolibrary.org/obo/UBERON_0010366` +#### Removed +- [conjunctival vasculature](http://purl.obolibrary.org/obo/UBERON_0010366) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "venae conjunctivales" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [conjunctival vasculature](http://purl.obolibrary.org/obo/UBERON_0010366) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "venae conjunctivales" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### connective tissue cell `http://purl.obolibrary.org/obo/CL_0002320` + +#### Added +- [connective tissue cell](http://purl.obolibrary.org/obo/CL_0002320) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### contractile cell `http://purl.obolibrary.org/obo/CL_0000183` + +#### Added +- [contractile cell](http://purl.obolibrary.org/obo/CL_0000183) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### conventional dendritic cell `http://purl.obolibrary.org/obo/CL_0000990` + +#### Added +- [conventional dendritic cell](http://purl.obolibrary.org/obo/CL_0000990) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### cord blood hematopoietic stem cell `http://purl.obolibrary.org/obo/CL_2000095` + +#### Added +- [cord blood hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_2000095) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### corneal endothelial cell `http://purl.obolibrary.org/obo/CL_0000132` + +#### Added +- [corneal endothelial cell](http://purl.obolibrary.org/obo/CL_0000132) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### corneal endothelium `http://purl.obolibrary.org/obo/UBERON_0001985` +#### Removed +- [corneal endothelium](http://purl.obolibrary.org/obo/UBERON_0001985) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "epithelium posterius corneae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Corneal_endothelium" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [corneal endothelium](http://purl.obolibrary.org/obo/UBERON_0001985) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "epithelium posterius corneae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Corneal_endothelium" + + +### corneal epithelial cell `http://purl.obolibrary.org/obo/CL_0000575` + +#### Added +- [corneal epithelial cell](http://purl.obolibrary.org/obo/CL_0000575) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### corneal epithelium `http://purl.obolibrary.org/obo/UBERON_0001772` +#### Removed +- [corneal epithelium](http://purl.obolibrary.org/obo/UBERON_0001772) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "e. anterius corneae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Corneal_epithelium" + +- [corneal epithelium](http://purl.obolibrary.org/obo/UBERON_0001772) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "epithelium anterius corneae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:58263" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [corneal epithelium](http://purl.obolibrary.org/obo/UBERON_0001772) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "e. anterius corneae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Corneal_epithelium" + +- [corneal epithelium](http://purl.obolibrary.org/obo/UBERON_0001772) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "epithelium anterius corneae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:58263" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### corneo-scleral junction `http://purl.obolibrary.org/obo/UBERON_0006761` +#### Removed +- [corneo-scleral junction](http://purl.obolibrary.org/obo/UBERON_0006761) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "limbus corneae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Corneal_limbus" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [corneo-scleral junction](http://purl.obolibrary.org/obo/UBERON_0006761) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "limbus corneae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Corneal_limbus" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [corneo-scleral junction](http://purl.obolibrary.org/obo/UBERON_0006761) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "limbus corneae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Corneal_limbus" + +- [corneo-scleral junction](http://purl.obolibrary.org/obo/UBERON_0006761) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "limbus corneae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Corneal_limbus" + + +### cortex of kidney `http://purl.obolibrary.org/obo/UBERON_0001225` +#### Removed +- [cortex of kidney](http://purl.obolibrary.org/obo/UBERON_0001225) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cortex renalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:15581" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [cortex of kidney](http://purl.obolibrary.org/obo/UBERON_0001225) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cortex renalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:15581" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### cortex of lymph node `http://purl.obolibrary.org/obo/UBERON_0002006` +#### Removed +- [cortex of lymph node](http://purl.obolibrary.org/obo/UBERON_0002006) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cortex nodi lymphoidei" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Cortex_of_lymph_node" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [cortex of lymph node](http://purl.obolibrary.org/obo/UBERON_0002006) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cortex nodi lymphoidei" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Cortex_of_lymph_node" + + +### cortical cell of adrenal gland `http://purl.obolibrary.org/obo/CL_0002097` + +#### Added +- [cortical cell of adrenal gland](http://purl.obolibrary.org/obo/CL_0002097) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### cortical interneuron `http://purl.obolibrary.org/obo/CL_0008031` + +#### Added +- [cortical interneuron](http://purl.obolibrary.org/obo/CL_0008031) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### cortical layer I `http://purl.obolibrary.org/obo/UBERON_0005390` +#### Removed +- [cortical layer I](http://purl.obolibrary.org/obo/UBERON_0005390) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lamina molecularis isocorticis [lamina I]" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:83900" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [cortical layer I](http://purl.obolibrary.org/obo/UBERON_0005390) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lamina molecularis isocorticis [lamina I]" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:83900" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### cortical layer II `http://purl.obolibrary.org/obo/UBERON_0005391` +#### Removed +- [cortical layer II](http://purl.obolibrary.org/obo/UBERON_0005391) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lamina granularis externa isocorticis [lamina ii]" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:77804" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [cortical layer II](http://purl.obolibrary.org/obo/UBERON_0005391) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lamina granularis externa isocorticis [lamina ii]" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:77804" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### cortical layer III `http://purl.obolibrary.org/obo/UBERON_0005392` +#### Removed +- [cortical layer III](http://purl.obolibrary.org/obo/UBERON_0005392) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "lamina pyramidalis externa" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:2448" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [cortical layer III](http://purl.obolibrary.org/obo/UBERON_0005392) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lamina pyramidalis externa isocorticis [lamina iii]" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:77810" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [cortical layer III](http://purl.obolibrary.org/obo/UBERON_0005392) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lamina pyramidalis externa isocorticis [lamina iii]" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:77810" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [cortical layer III](http://purl.obolibrary.org/obo/UBERON_0005392) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "lamina pyramidalis externa" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:2448" + + +### cortical layer IV `http://purl.obolibrary.org/obo/UBERON_0005393` +#### Removed +- [cortical layer IV](http://purl.obolibrary.org/obo/UBERON_0005393) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lamina granularis interna isocorticis [lamina iv]" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:77811" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [cortical layer IV](http://purl.obolibrary.org/obo/UBERON_0005393) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lamina granularis interna isocorticis [lamina iv]" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:77811" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### cortical layer V `http://purl.obolibrary.org/obo/UBERON_0005394` +#### Removed +- [cortical layer V](http://purl.obolibrary.org/obo/UBERON_0005394) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "lamina ganglionaris" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:2450" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [cortical layer V](http://purl.obolibrary.org/obo/UBERON_0005394) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "lamina pyramidalis interna" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:2450" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [cortical layer V](http://purl.obolibrary.org/obo/UBERON_0005394) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lamina pyramidalis interna isocorticis [lamina v]" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:77812" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [cortical layer V](http://purl.obolibrary.org/obo/UBERON_0005394) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lamina pyramidalis interna isocorticis [lamina v]" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:77812" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [cortical layer V](http://purl.obolibrary.org/obo/UBERON_0005394) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "lamina ganglionaris" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:2450" + +- [cortical layer V](http://purl.obolibrary.org/obo/UBERON_0005394) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "lamina pyramidalis interna" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:2450" + + +### cortical layer VI `http://purl.obolibrary.org/obo/UBERON_0005395` +#### Removed +- [cortical layer VI](http://purl.obolibrary.org/obo/UBERON_0005395) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lamina multiformis isocorticis [lamina vi]" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:77805" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [cortical layer VI](http://purl.obolibrary.org/obo/UBERON_0005395) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "lamina multiformis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:2451" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [cortical layer VI](http://purl.obolibrary.org/obo/UBERON_0005395) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "lamina multiformis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:2451" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [cortical layer VI](http://purl.obolibrary.org/obo/UBERON_0005395) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lamina multiformis isocorticis [lamina vi]" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:77805" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### cortical plate `http://purl.obolibrary.org/obo/UBERON_0005343` + +#### Added +- [cortical plate](http://purl.obolibrary.org/obo/UBERON_0005343) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D002540" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [LexicalMatching](https://w3id.org/semapv/vocab/LexicalMatching) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### cortical subplate `http://purl.obolibrary.org/obo/UBERON_0004035` + +#### Added +- [cortical subplate](http://purl.obolibrary.org/obo/UBERON_0004035) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "VO:0011276" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + - [author_id](https://w3id.org/sssom/author_id) [0000-0003-4423-4370](https://orcid.org/0000-0003-4423-4370) + + +### cortical thymic epithelial cell `http://purl.obolibrary.org/obo/CL_0002364` + +#### Added +- [cortical thymic epithelial cell](http://purl.obolibrary.org/obo/CL_0002364) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### corticospinal tract `http://purl.obolibrary.org/obo/UBERON_0002707` +#### Removed +- [corticospinal tract](http://purl.obolibrary.org/obo/UBERON_0002707) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tractus cortico-spinalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:1320" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [corticospinal tract](http://purl.obolibrary.org/obo/UBERON_0002707) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tractus corticospinalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Corticospinal_tract" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:1320" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [corticospinal tract](http://purl.obolibrary.org/obo/UBERON_0002707) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0006132" + - [contributor](http://purl.org/dc/terms/contributor) "https://orcid.org/0000-0003-4423-4370" + +- [corticospinal tract](http://purl.obolibrary.org/obo/UBERON_0002707) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "fasciculus pyramidalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:800" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [corticospinal tract](http://purl.obolibrary.org/obo/UBERON_0002707) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "fibrae corticospinales" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:1320" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [corticospinal tract](http://purl.obolibrary.org/obo/UBERON_0002707) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tractus pyramidalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:800" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [corticospinal tract](http://purl.obolibrary.org/obo/UBERON_0002707) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "fasciculus cerebro-spinalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:1320" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [corticospinal tract](http://purl.obolibrary.org/obo/UBERON_0002707) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "fasciculus cerebro-spinalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:1320" + +- [corticospinal tract](http://purl.obolibrary.org/obo/UBERON_0002707) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tractus corticospinalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Corticospinal_tract" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:1320" + +- [corticospinal tract](http://purl.obolibrary.org/obo/UBERON_0002707) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "fasciculus pyramidalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:800" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [corticospinal tract](http://purl.obolibrary.org/obo/UBERON_0002707) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tractus cortico-spinalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:1320" + +- [corticospinal tract](http://purl.obolibrary.org/obo/UBERON_0002707) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tractus pyramidalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:800" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [corticospinal tract](http://purl.obolibrary.org/obo/UBERON_0002707) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0006132" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + - [author_id](https://w3id.org/sssom/author_id) [0000-0003-4423-4370](https://orcid.org/0000-0003-4423-4370) + +- [corticospinal tract](http://purl.obolibrary.org/obo/UBERON_0002707) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "fibrae corticospinales" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:1320" + + +### corticothalamic-projecting glutamatergic cortical neuron `http://purl.obolibrary.org/obo/CL_4023013` + +#### Added +- [corticothalamic-projecting glutamatergic cortical neuron](http://purl.obolibrary.org/obo/CL_4023013) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### costal diaphragm `http://purl.obolibrary.org/obo/UBERON_0035831` + +#### Added +- [costal diaphragm](http://purl.obolibrary.org/obo/UBERON_0035831) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "uberon" + +- [costal diaphragm](http://purl.obolibrary.org/obo/UBERON_0035831) [id](http://www.geneontology.org/formats/oboInOwl#id) "UBERON:0035831" + +- [costal diaphragm](http://purl.obolibrary.org/obo/UBERON_0035831) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "SCTID:368048007" + +- [costal diaphragm](http://purl.obolibrary.org/obo/UBERON_0035831) [label](http://www.w3.org/2000/01/rdf-schema#label) "costal diaphragm" + +- [costal diaphragm](http://purl.obolibrary.org/obo/UBERON_0035831) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "costal part of diaphragm" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:58277" + +- [costal diaphragm](http://purl.obolibrary.org/obo/UBERON_0035831) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The domain of the diaphragm that is a thin domed sheet of muscle composed of a radial array of myofibers extending laterally from the ribs and medially to a central tendon." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:23586979" + +- [costal diaphragm](http://purl.obolibrary.org/obo/UBERON_0035831) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pars costalis diaphragmatis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [costal diaphragm](http://purl.obolibrary.org/obo/UBERON_0035831) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:58277" + +- Class: [costal diaphragm](http://purl.obolibrary.org/obo/UBERON_0035831) + +- [costal diaphragm](http://purl.obolibrary.org/obo/UBERON_0035831) SubClassOf [organ subunit](http://purl.obolibrary.org/obo/UBERON_0000063) + +- [costal diaphragm](http://purl.obolibrary.org/obo/UBERON_0035831) SubClassOf [lateral structure](http://purl.obolibrary.org/obo/UBERON_0015212) + +- [costal diaphragm](http://purl.obolibrary.org/obo/UBERON_0035831) SubClassOf [attached to](http://purl.obolibrary.org/obo/RO_0002371) some [central tendon of diaphragm](http://purl.obolibrary.org/obo/UBERON_0006670) + +- [costal diaphragm](http://purl.obolibrary.org/obo/UBERON_0035831) SubClassOf [in lateral side of](http://purl.obolibrary.org/obo/BSPO_0000126) some [diaphragm](http://purl.obolibrary.org/obo/UBERON_0001103) + - [source](http://www.geneontology.org/formats/oboInOwl#source) "PMID:23586979" + +- [costal diaphragm](http://purl.obolibrary.org/obo/UBERON_0035831) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [diaphragm](http://purl.obolibrary.org/obo/UBERON_0001103) + - [source](http://www.geneontology.org/formats/oboInOwl#source) "PMID:23586979" + + +### costo-cervical trunk `http://purl.obolibrary.org/obo/UBERON_0004688` +#### Removed +- [costo-cervical trunk](http://purl.obolibrary.org/obo/UBERON_0004688) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "truncus costocervicalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Costocervical_trunk" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [costo-cervical trunk](http://purl.obolibrary.org/obo/UBERON_0004688) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "truncus costocervicalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Costocervical_trunk" + + +### cranial cavity `http://purl.obolibrary.org/obo/UBERON_0013411` +#### Removed +- [cranial cavity](http://purl.obolibrary.org/obo/UBERON_0013411) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cavitas cranii" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:9644" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [cranial cavity](http://purl.obolibrary.org/obo/UBERON_0013411) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cavitas cranii" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:9644" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### cranial nerve `http://purl.obolibrary.org/obo/UBERON_0001785` +#### Removed +- [cranial nerve](http://purl.obolibrary.org/obo/UBERON_0001785) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nervus cranialis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Cranial_nerve" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [cranial nerve](http://purl.obolibrary.org/obo/UBERON_0001785) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nervus cranialis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Cranial_nerve" + + +### cranial nerve II `http://purl.obolibrary.org/obo/UBERON_0000941` +#### Removed +- [cranial nerve II](http://purl.obolibrary.org/obo/UBERON_0000941) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nervus opticus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [cranial nerve II](http://purl.obolibrary.org/obo/UBERON_0000941) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nervus opticus [II]" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:50863" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [cranial nerve II](http://purl.obolibrary.org/obo/UBERON_0000941) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nervus opticus [II]" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:50863" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [cranial nerve II](http://purl.obolibrary.org/obo/UBERON_0000941) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nervus opticus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### cranial nerve nucleus `http://purl.obolibrary.org/obo/UBERON_0000126` +#### Removed +- [cranial nerve nucleus](http://purl.obolibrary.org/obo/UBERON_0000126) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus nervi cranialis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Cranial_nerve_nucleus" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [cranial nerve nucleus](http://purl.obolibrary.org/obo/UBERON_0000126) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus nervi cranialis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Cranial_nerve_nucleus" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### cranial neural crest `http://purl.obolibrary.org/obo/UBERON_0003099` +#### Removed +- [cranial neural crest](http://purl.obolibrary.org/obo/UBERON_0003099) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "crista neuralis cranialis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Cranial_neural_crest" + +#### Added +- [cranial neural crest](http://purl.obolibrary.org/obo/UBERON_0003099) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "crista neuralis cranialis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Cranial_neural_crest" + + +### cranium `http://purl.obolibrary.org/obo/UBERON_0003128` +#### Removed +- [cranium](http://purl.obolibrary.org/obo/UBERON_0003128) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ossa cranii" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:71325" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [cranium](http://purl.obolibrary.org/obo/UBERON_0003128) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D012886" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [LexicalMatching](https://w3id.org/semapv/vocab/LexicalMatching) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + +- [cranium](http://purl.obolibrary.org/obo/UBERON_0003128) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ossa cranii" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:71325" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### crista terminalis `http://purl.obolibrary.org/obo/UBERON_0005979` +#### Removed +- [crista terminalis](http://purl.obolibrary.org/obo/UBERON_0005979) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "crista terminalis atrii dextri" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:9236" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [crista terminalis](http://purl.obolibrary.org/obo/UBERON_0005979) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "crista terminalis atrii dextri" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:9236" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### crus of diaphragm `http://purl.obolibrary.org/obo/UBERON_0014765` + +#### Added +- [crus of diaphragm](http://purl.obolibrary.org/obo/UBERON_0014765) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "Classification notes: May be considered an external sphincter[PMID:8224664]" + +- [crus of diaphragm](http://purl.obolibrary.org/obo/UBERON_0014765) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "crural diaphragm" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:23586979" + +- [crus of diaphragm](http://purl.obolibrary.org/obo/UBERON_0014765) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "crus of the diaphragm" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Crus_of_diaphragm" + +- [crus of diaphragm](http://purl.obolibrary.org/obo/UBERON_0014765) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "diaphragm crura" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [plural form](http://purl.obolibrary.org/obo/OMO_0003004) + +- [crus of diaphragm](http://purl.obolibrary.org/obo/UBERON_0014765) [label](http://www.w3.org/2000/01/rdf-schema#label) "crus of diaphragm" + +- [crus of diaphragm](http://purl.obolibrary.org/obo/UBERON_0014765) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "EMAPA:17703" + +- [crus of diaphragm](http://purl.obolibrary.org/obo/UBERON_0014765) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "VHOG:0001546" + +- [crus of diaphragm](http://purl.obolibrary.org/obo/UBERON_0014765) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "SCTID:244668003" + +- [crus of diaphragm](http://purl.obolibrary.org/obo/UBERON_0014765) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The domain of the diaphragm that is located dorsally and attaches to the vertebrae and surrounds the esophagus and aorta." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:23586979" + +- [crus of diaphragm](http://purl.obolibrary.org/obo/UBERON_0014765) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "EHDAA2:0000597" + +- [crus of diaphragm](http://purl.obolibrary.org/obo/UBERON_0014765) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Crus_of_diaphragm" + +- [crus of diaphragm](http://purl.obolibrary.org/obo/UBERON_0014765) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "diaphragmatic crura" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Crus_of_diaphragm" + +- [crus of diaphragm](http://purl.obolibrary.org/obo/UBERON_0014765) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "crura of the diaphragm" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Crus_of_diaphragm" + +- [crus of diaphragm](http://purl.obolibrary.org/obo/UBERON_0014765) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "uberon" + +- [crus of diaphragm](http://purl.obolibrary.org/obo/UBERON_0014765) [id](http://www.geneontology.org/formats/oboInOwl#id) "UBERON:0014765" + +- Class: [crus of diaphragm](http://purl.obolibrary.org/obo/UBERON_0014765) + +- [crus of diaphragm](http://purl.obolibrary.org/obo/UBERON_0014765) SubClassOf [attached to](http://purl.obolibrary.org/obo/RO_0002371) some [vertebral column](http://purl.obolibrary.org/obo/UBERON_0001130) + +- [crus of diaphragm](http://purl.obolibrary.org/obo/UBERON_0014765) SubClassOf [intersects midsagittal plane of](http://purl.obolibrary.org/obo/BSPO_0005001) some [diaphragm](http://purl.obolibrary.org/obo/UBERON_0001103) + - [source](http://www.geneontology.org/formats/oboInOwl#source) "PMID:23586979" + +- [crus of diaphragm](http://purl.obolibrary.org/obo/UBERON_0014765) SubClassOf [attached to](http://purl.obolibrary.org/obo/RO_0002371) some [central tendon of diaphragm](http://purl.obolibrary.org/obo/UBERON_0006670) + +- [crus of diaphragm](http://purl.obolibrary.org/obo/UBERON_0014765) SubClassOf [organ subunit](http://purl.obolibrary.org/obo/UBERON_0000063) + +- [crus of diaphragm](http://purl.obolibrary.org/obo/UBERON_0014765) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [diaphragm](http://purl.obolibrary.org/obo/UBERON_0001103) + - [source](http://www.geneontology.org/formats/oboInOwl#source) "PMID:23586979" + + +### cystic duct `http://purl.obolibrary.org/obo/UBERON_0001152` +#### Removed +- [cystic duct](http://purl.obolibrary.org/obo/UBERON_0001152) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ductus cysticus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Cystic_duct" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [cystic duct](http://purl.obolibrary.org/obo/UBERON_0001152) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ductus cysticus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Cystic_duct" + + +### cytoplasm `http://purl.obolibrary.org/obo/GO_0005737` +#### Removed +- [cytoplasm](http://purl.obolibrary.org/obo/GO_0005737) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [prokaryote_subset](http://purl.obolibrary.org/obo/go#prokaryote_subset) + +#### Added +- [cytoplasm](http://purl.obolibrary.org/obo/GO_0005737) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_prokaryote](http://purl.obolibrary.org/obo/go#goslim_prokaryote) + + +### cytoplasmic transport, nurse cell to oocyte `http://purl.obolibrary.org/obo/GO_0007303` +#### Removed +- [cytoplasmic transport, nurse cell to oocyte](http://purl.obolibrary.org/obo/GO_0007303) [label](http://www.w3.org/2000/01/rdf-schema#label) "cytoplasmic transport, nurse cell to oocyte" + +- [cytoplasmic transport, nurse cell to oocyte](http://purl.obolibrary.org/obo/GO_0007303) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0007303" + +- [cytoplasmic transport, nurse cell to oocyte](http://purl.obolibrary.org/obo/GO_0007303) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The directed movement of cytoplasmic constituents synthesized in the nurse cells to the oocyte." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0879694238" + +- [cytoplasmic transport, nurse cell to oocyte](http://purl.obolibrary.org/obo/GO_0007303) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- Class: [cytoplasmic transport, nurse cell to oocyte](http://purl.obolibrary.org/obo/GO_0007303) + +- [cytoplasmic transport, nurse cell to oocyte](http://purl.obolibrary.org/obo/GO_0007303) EquivalentTo [cytosolic transport](http://purl.obolibrary.org/obo/GO_0016482) and ([has target start location](http://purl.obolibrary.org/obo/RO_0002338) some [invertebrate nurse cell](http://purl.obolibrary.org/obo/CL_0000026)) and ([has target end location](http://purl.obolibrary.org/obo/RO_0002339) some [oocyte](http://purl.obolibrary.org/obo/CL_0000023)) + +- [cytoplasmic transport, nurse cell to oocyte](http://purl.obolibrary.org/obo/GO_0007303) SubClassOf [has target end location](http://purl.obolibrary.org/obo/RO_0002339) some [oocyte](http://purl.obolibrary.org/obo/CL_0000023) + +- [cytoplasmic transport, nurse cell to oocyte](http://purl.obolibrary.org/obo/GO_0007303) SubClassOf [has target start location](http://purl.obolibrary.org/obo/RO_0002338) some [invertebrate nurse cell](http://purl.obolibrary.org/obo/CL_0000026) + +- [cytoplasmic transport, nurse cell to oocyte](http://purl.obolibrary.org/obo/GO_0007303) SubClassOf [cytosolic transport](http://purl.obolibrary.org/obo/GO_0016482) + +- [cytoplasmic transport, nurse cell to oocyte](http://purl.obolibrary.org/obo/GO_0007303) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [ovarian nurse cell to oocyte transport](http://purl.obolibrary.org/obo/GO_0007300) + +- [cytoplasmic transport, nurse cell to oocyte](http://purl.obolibrary.org/obo/GO_0007303) SubClassOf [cellular process involved in reproduction in multicellular organism](http://purl.obolibrary.org/obo/GO_0022412) + + + +### cytoskeletal protein binding `http://purl.obolibrary.org/obo/GO_0008092` +#### Removed +- [cytoskeletal protein binding](http://purl.obolibrary.org/obo/GO_0008092) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [prokaryote_subset](http://purl.obolibrary.org/obo/go#prokaryote_subset) + +#### Added +- [cytoskeletal protein binding](http://purl.obolibrary.org/obo/GO_0008092) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_prokaryote](http://purl.obolibrary.org/obo/go#goslim_prokaryote) + + +### cytoskeleton `http://purl.obolibrary.org/obo/GO_0005856` +#### Removed +- [cytoskeleton](http://purl.obolibrary.org/obo/GO_0005856) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [prokaryote_subset](http://purl.obolibrary.org/obo/go#prokaryote_subset) + +#### Added +- [cytoskeleton](http://purl.obolibrary.org/obo/GO_0005856) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_prokaryote](http://purl.obolibrary.org/obo/go#goslim_prokaryote) + + +### cytoskeleton organization `http://purl.obolibrary.org/obo/GO_0007010` +#### Removed +- [cytoskeleton organization](http://purl.obolibrary.org/obo/GO_0007010) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [prokaryote_subset](http://purl.obolibrary.org/obo/go#prokaryote_subset) + +#### Added +- [cytoskeleton organization](http://purl.obolibrary.org/obo/GO_0007010) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_prokaryote](http://purl.obolibrary.org/obo/go#goslim_prokaryote) + + +### cytoskeleton-dependent cytoplasmic transport, nurse cell to oocyte `http://purl.obolibrary.org/obo/GO_0019749` +#### Removed +- [cytoskeleton-dependent cytoplasmic transport, nurse cell to oocyte](http://purl.obolibrary.org/obo/GO_0019749) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [cytoskeleton-dependent cytoplasmic transport, nurse cell to oocyte](http://purl.obolibrary.org/obo/GO_0019749) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0019749" + +- [cytoskeleton-dependent cytoplasmic transport, nurse cell to oocyte](http://purl.obolibrary.org/obo/GO_0019749) [label](http://www.w3.org/2000/01/rdf-schema#label) "cytoskeleton-dependent cytoplasmic transport, nurse cell to oocyte" + +- [cytoskeleton-dependent cytoplasmic transport, nurse cell to oocyte](http://purl.obolibrary.org/obo/GO_0019749) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The directed movement of substances along cytoskeletal elements, such as microfilaments or microtubules, from a nurse cell to an oocyte." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" + +- Class: [cytoskeleton-dependent cytoplasmic transport, nurse cell to oocyte](http://purl.obolibrary.org/obo/GO_0019749) + +- [cytoskeleton-dependent cytoplasmic transport, nurse cell to oocyte](http://purl.obolibrary.org/obo/GO_0019749) EquivalentTo [cytoplasmic transport, nurse cell to oocyte](http://purl.obolibrary.org/obo/GO_0007303) and [cytoskeleton-dependent intracellular transport](http://purl.obolibrary.org/obo/GO_0030705) + +- [cytoskeleton-dependent cytoplasmic transport, nurse cell to oocyte](http://purl.obolibrary.org/obo/GO_0019749) SubClassOf [cytoplasmic transport, nurse cell to oocyte](http://purl.obolibrary.org/obo/GO_0007303) + +- [cytoskeleton-dependent cytoplasmic transport, nurse cell to oocyte](http://purl.obolibrary.org/obo/GO_0019749) SubClassOf [cytoskeleton-dependent intracellular transport](http://purl.obolibrary.org/obo/GO_0030705) + + + +### cytosolic transport `http://purl.obolibrary.org/obo/GO_0016482` + +#### Added +- [cytosolic transport](http://purl.obolibrary.org/obo/GO_0016482) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) "https://github.com/geneontology/go-ontology/issues/26386"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + + +### cytotoxic T cell `http://purl.obolibrary.org/obo/CL_0000910` + +#### Added +- [cytotoxic T cell](http://purl.obolibrary.org/obo/CL_0000910) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### decidual cell `http://purl.obolibrary.org/obo/CL_2000002` + +#### Added +- [decidual cell](http://purl.obolibrary.org/obo/CL_2000002) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### decidual natural killer cell, human `http://purl.obolibrary.org/obo/CL_0002343` + +#### Added +- [decidual natural killer cell, human](http://purl.obolibrary.org/obo/CL_0002343) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### defense response to other organism `http://purl.obolibrary.org/obo/GO_0098542` +#### Removed +- [defense response to other organism](http://purl.obolibrary.org/obo/GO_0098542) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [prokaryote_subset](http://purl.obolibrary.org/obo/go#prokaryote_subset) + +#### Added +- [defense response to other organism](http://purl.obolibrary.org/obo/GO_0098542) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_prokaryote](http://purl.obolibrary.org/obo/go#goslim_prokaryote) + + +### defense response to symbiont `http://purl.obolibrary.org/obo/GO_0140546` + +#### Added +- [defense response to symbiont](http://purl.obolibrary.org/obo/GO_0140546) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) "https://github.com/geneontology/go-ontology/issues/20261"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + +- [defense response to symbiont](http://purl.obolibrary.org/obo/GO_0140546) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Reactions triggered in response to the presence of a symbiont that act to protect or prevent damage to the host." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:pg" + +- [defense response to symbiont](http://purl.obolibrary.org/obo/GO_0140546) [created by](http://www.geneontology.org/formats/oboInOwl#created_by) "pg" + +- [defense response to symbiont](http://purl.obolibrary.org/obo/GO_0140546) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [defense response to symbiont](http://purl.obolibrary.org/obo/GO_0140546) [creation date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2020-11-11T17:19:06Z" + +- [defense response to symbiont](http://purl.obolibrary.org/obo/GO_0140546) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0140546" + +- [defense response to symbiont](http://purl.obolibrary.org/obo/GO_0140546) [label](http://www.w3.org/2000/01/rdf-schema#label) "defense response to symbiont" + +- Class: [defense response to symbiont](http://purl.obolibrary.org/obo/GO_0140546) + +- [defense response to symbiont](http://purl.obolibrary.org/obo/GO_0140546) SubClassOf [defense response to other organism](http://purl.obolibrary.org/obo/GO_0098542) + + +### deferent duct artery `http://purl.obolibrary.org/obo/UBERON_0005192` +#### Removed +- [deferent duct artery](http://purl.obolibrary.org/obo/UBERON_0005192) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "arteria ductus deferentis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Artery_to_the_ductus_deferens" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [deferent duct artery](http://purl.obolibrary.org/obo/UBERON_0005192) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "arteria ductus deferentis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Artery_to_the_ductus_deferens" + + +### deltoid `http://purl.obolibrary.org/obo/UBERON_0001476` +#### Removed +- [deltoid](http://purl.obolibrary.org/obo/UBERON_0001476) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "musculus deltoideus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Deltoid_muscle" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [deltoid](http://purl.obolibrary.org/obo/UBERON_0001476) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "musculus deltoideus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Deltoid_muscle" + + +### deltopectoral crest `http://purl.obolibrary.org/obo/UBERON_0002498` +#### Removed +- [deltopectoral crest](http://purl.obolibrary.org/obo/UBERON_0002498) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tuberositas deltoidea humeri" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Deltoid_tuberosity" + +- [deltopectoral crest](http://purl.obolibrary.org/obo/UBERON_0002498) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tuberositas deltoidea" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:23418" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [deltopectoral crest](http://purl.obolibrary.org/obo/UBERON_0002498) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tuberositas deltoidea humeri" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Deltoid_tuberosity" + +- [deltopectoral crest](http://purl.obolibrary.org/obo/UBERON_0002498) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tuberositas deltoidea" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:23418" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### dendritic cell `http://purl.obolibrary.org/obo/CL_0000451` + +#### Added +- [dendritic cell](http://purl.obolibrary.org/obo/CL_0000451) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### dendritic cell, human `http://purl.obolibrary.org/obo/CL_0001056` + +#### Added +- [dendritic cell, human](http://purl.obolibrary.org/obo/CL_0001056) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### dental follicle `http://purl.obolibrary.org/obo/UBERON_0008969` + +#### Added +- [dental follicle](http://purl.obolibrary.org/obo/UBERON_0008969) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D003795" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [LexicalMatching](https://w3id.org/semapv/vocab/LexicalMatching) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### dentate gyrus granule cell layer `http://purl.obolibrary.org/obo/UBERON_0005381` +#### Removed +- [dentate gyrus granule cell layer](http://purl.obolibrary.org/obo/UBERON_0005381) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "stratum granulare gyri dentati" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:83146" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [dentate gyrus granule cell layer](http://purl.obolibrary.org/obo/UBERON_0005381) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "stratum granulare gyri dentati" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:83146" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### dentate gyrus molecular layer `http://purl.obolibrary.org/obo/UBERON_0004679` +#### Removed +- [dentate gyrus molecular layer](http://purl.obolibrary.org/obo/UBERON_0004679) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "stratum moleculare gyri dentati" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:83677" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [dentate gyrus molecular layer](http://purl.obolibrary.org/obo/UBERON_0004679) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "stratum moleculare gyri dentati" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:83677" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### dentate gyrus of hippocampal formation `http://purl.obolibrary.org/obo/UBERON_0001885` +#### Removed +- [dentate gyrus of hippocampal formation](http://purl.obolibrary.org/obo/UBERON_0001885) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "gyrus dentatus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0002496" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Dentate_gyrus" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [dentate gyrus of hippocampal formation](http://purl.obolibrary.org/obo/UBERON_0001885) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "gyrus dentatus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0002496" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Dentate_gyrus" + + +### dentate gyrus polymorphic layer `http://purl.obolibrary.org/obo/UBERON_0002928` +#### Removed +- [dentate gyrus polymorphic layer](http://purl.obolibrary.org/obo/UBERON_0002928) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "CA4" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [DUBIOUS](http://purl.obolibrary.org/obo/uberon/core#DUBIOUS) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:17765709" + +#### Added +- [dentate gyrus polymorphic layer](http://purl.obolibrary.org/obo/UBERON_0002928) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "CA4" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:17765709" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003002](http://purl.obolibrary.org/obo/OMO_0003002) + + +### dentition `http://purl.obolibrary.org/obo/UBERON_0003672` +#### Removed +- [dentition](http://purl.obolibrary.org/obo/UBERON_0003672) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "dentes" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:75150" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [dentition](http://purl.obolibrary.org/obo/UBERON_0003672) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "dentes" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:75150" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### dermal papilla `http://purl.obolibrary.org/obo/UBERON_0000412` +#### Removed +- [dermal papilla](http://purl.obolibrary.org/obo/UBERON_0000412) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "papillae dermis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Dermal_papillae" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [dermal papilla](http://purl.obolibrary.org/obo/UBERON_0000412) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "papillae dermis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Dermal_papillae" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### dermatological-muscosal system `http://purl.obolibrary.org/obo/UBERON_0012125` + +#### Added +- [dermatological-muscosal system](http://purl.obolibrary.org/obo/UBERON_0012125) [id](http://www.geneontology.org/formats/oboInOwl#id) "UBERON:0012125" + +- [dermatological-muscosal system](http://purl.obolibrary.org/obo/UBERON_0012125) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Anatomical system that consists of the integumental system plus all mucosae and submucosae." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "https://github.com/obophenotype/uberon/issues/53" + +- [dermatological-muscosal system](http://purl.obolibrary.org/obo/UBERON_0012125) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "uberon" + +- [dermatological-muscosal system](http://purl.obolibrary.org/obo/UBERON_0012125) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "dermatological system" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "OBI:MC" + +- [dermatological-muscosal system](http://purl.obolibrary.org/obo/UBERON_0012125) [label](http://www.w3.org/2000/01/rdf-schema#label) "dermatological-muscosal system" + +- Class: [dermatological-muscosal system](http://purl.obolibrary.org/obo/UBERON_0012125) + +- [dermatological-muscosal system](http://purl.obolibrary.org/obo/UBERON_0012125) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [hypodermis](http://purl.obolibrary.org/obo/UBERON_0002072) + +- [dermatological-muscosal system](http://purl.obolibrary.org/obo/UBERON_0012125) SubClassOf [protein-containing material entity](http://purl.obolibrary.org/obo/PR_000050567) + +- [dermatological-muscosal system](http://purl.obolibrary.org/obo/UBERON_0012125) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [skin of body](http://purl.obolibrary.org/obo/UBERON_0002097) + +- [dermatological-muscosal system](http://purl.obolibrary.org/obo/UBERON_0012125) SubClassOf [anatomical system](http://purl.obolibrary.org/obo/UBERON_0000467) + +- [dermatological-muscosal system](http://purl.obolibrary.org/obo/UBERON_0012125) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [submucosa](http://purl.obolibrary.org/obo/UBERON_0000009) + +- [dermatological-muscosal system](http://purl.obolibrary.org/obo/UBERON_0012125) SubClassOf [existence ends during](http://purl.obolibrary.org/obo/RO_0002492) some [fully formed stage](http://purl.obolibrary.org/obo/UBERON_0000066) + +- [dermatological-muscosal system](http://purl.obolibrary.org/obo/UBERON_0012125) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [mucosa](http://purl.obolibrary.org/obo/UBERON_0000344) + + +### dermatome `http://purl.obolibrary.org/obo/UBERON_0004016` +#### Removed +- [dermatome](http://purl.obolibrary.org/obo/UBERON_0004016) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0006248" + - [contributor](http://purl.org/dc/terms/contributor) "https://orcid.org/0000-0003-4423-4370" + +- [dermatome](http://purl.obolibrary.org/obo/UBERON_0004016) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "mesenchyma dermatomiale" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Dermatomal_mesenchyme" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [dermatome](http://purl.obolibrary.org/obo/UBERON_0004016) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0006248" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + - [author_id](https://w3id.org/sssom/author_id) [0000-0003-4423-4370](https://orcid.org/0000-0003-4423-4370) + +- [dermatome](http://purl.obolibrary.org/obo/UBERON_0004016) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "mesenchyma dermatomiale" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Dermatomal_mesenchyme" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### dermis `http://purl.obolibrary.org/obo/UBERON_0002067` +#### Removed +- [dermis](http://purl.obolibrary.org/obo/UBERON_0002067) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "corium" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Dermis" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0000294" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [dermis](http://purl.obolibrary.org/obo/UBERON_0002067) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "corium" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Dermis" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0000294" + + +### dermis microvascular lymphatic vessel endothelial cell `http://purl.obolibrary.org/obo/CL_2000041` + +#### Added +- [dermis microvascular lymphatic vessel endothelial cell](http://purl.obolibrary.org/obo/CL_2000041) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### descending aorta `http://purl.obolibrary.org/obo/UBERON_0001514` +#### Removed +- [descending aorta](http://purl.obolibrary.org/obo/UBERON_0001514) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "pars descendens aortae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Descending_aorta" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [descending aorta](http://purl.obolibrary.org/obo/UBERON_0001514) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "aorta descendens" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Descending_aorta" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [descending aorta](http://purl.obolibrary.org/obo/UBERON_0001514) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "aorta descendens" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Descending_aorta" + +- [descending aorta](http://purl.obolibrary.org/obo/UBERON_0001514) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "pars descendens aortae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Descending_aorta" + + +### descending colon `http://purl.obolibrary.org/obo/UBERON_0001158` +#### Removed +- [descending colon](http://purl.obolibrary.org/obo/UBERON_0001158) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D044683" + +- [descending colon](http://purl.obolibrary.org/obo/UBERON_0001158) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "colon descendens" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Descending_colon" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [descending colon](http://purl.obolibrary.org/obo/UBERON_0001158) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D044683" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [author_id](https://w3id.org/sssom/author_id) [0000-0001-9439-5346](https://orcid.org/0000-0001-9439-5346) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + +- [descending colon](http://purl.obolibrary.org/obo/UBERON_0001158) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "colon descendens" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Descending_colon" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### detoxification `http://purl.obolibrary.org/obo/GO_0098754` +#### Removed +- [detoxification](http://purl.obolibrary.org/obo/GO_0098754) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [prokaryote_subset](http://purl.obolibrary.org/obo/go#prokaryote_subset) + +#### Added +- [detoxification](http://purl.obolibrary.org/obo/GO_0098754) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_prokaryote](http://purl.obolibrary.org/obo/go#goslim_prokaryote) + + +### developing anatomical structure `http://purl.obolibrary.org/obo/UBERON_0005423` +#### Removed +- [developing anatomical structure](http://purl.obolibrary.org/obo/UBERON_0005423) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007006" + +#### Added +- [developing anatomical structure](http://purl.obolibrary.org/obo/UBERON_0005423) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007006" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### developmental cell growth `http://purl.obolibrary.org/obo/GO_0048588` + +#### Added +- [developmental cell growth](http://purl.obolibrary.org/obo/GO_0048588) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [gocheck_do_not_annotate](http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate) + +- [developmental cell growth](http://purl.obolibrary.org/obo/GO_0048588) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) "https://github.com/geneontology/go-ontology/issues/26424"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + + +### develops into `http://purl.obolibrary.org/obo/RO_0002203` + +#### Added +- [develops into](http://purl.obolibrary.org/obo/RO_0002203) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "uberon" + +- [develops into](http://purl.obolibrary.org/obo/RO_0002203) [shorthand](http://www.geneontology.org/formats/oboInOwl#shorthand) "develops_into" + +- [develops into](http://purl.obolibrary.org/obo/RO_0002203) [id](http://www.geneontology.org/formats/oboInOwl#id) "develops_into" + +- [develops into](http://purl.obolibrary.org/obo/RO_0002203) [label](http://www.w3.org/2000/01/rdf-schema#label) "develops into" + +- [develops into](http://purl.obolibrary.org/obo/RO_0002203) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "RO:0002203" + + +### diaphysis of femur `http://purl.obolibrary.org/obo/UBERON_0006862` +#### Removed +- [diaphysis of femur](http://purl.obolibrary.org/obo/UBERON_0006862) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "corpus femoris" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:32847" + +#### Added +- [diaphysis of femur](http://purl.obolibrary.org/obo/UBERON_0006862) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "corpus femoris" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:32847" + + +### diencephalon `http://purl.obolibrary.org/obo/UBERON_0001894` +#### Removed +- [diencephalon](http://purl.obolibrary.org/obo/UBERON_0001894) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "diencephalon" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Diencephalon" + +#### Added +- [diencephalon](http://purl.obolibrary.org/obo/UBERON_0001894) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "diencephalon" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Diencephalon" + + +### differentiated genital tubercle `http://purl.obolibrary.org/obo/UBERON_0011757` +#### Removed +- [differentiated genital tubercle](http://purl.obolibrary.org/obo/UBERON_0011757) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "phallus primordialis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Primordial_phallus" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [differentiated genital tubercle](http://purl.obolibrary.org/obo/UBERON_0011757) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Primordial_phallus" + +#### Added +- [differentiated genital tubercle](http://purl.obolibrary.org/obo/UBERON_0011757) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "phallus primordialis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Primordial_phallus" + + +### differentiation-committed oligodendrocyte precursor `http://purl.obolibrary.org/obo/CL_4023059` + +#### Added +- [differentiation-committed oligodendrocyte precursor](http://purl.obolibrary.org/obo/CL_4023059) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### digestive system `http://purl.obolibrary.org/obo/UBERON_0001007` +#### Removed +- [digestive system](http://purl.obolibrary.org/obo/UBERON_0001007) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005055" + +#### Added +- [digestive system](http://purl.obolibrary.org/obo/UBERON_0001007) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005055" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### digestive tract `http://purl.obolibrary.org/obo/UBERON_0001555` +#### Removed +- [digestive tract](http://purl.obolibrary.org/obo/UBERON_0001555) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00003125" + +#### Added +- [digestive tract](http://purl.obolibrary.org/obo/UBERON_0001555) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00003125" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + +- [digestive tract](http://purl.obolibrary.org/obo/UBERON_0001555) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D041981" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [LexicalMatching](https://w3id.org/semapv/vocab/LexicalMatching) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### digestive tract diverticulum `http://purl.obolibrary.org/obo/UBERON_0009854` +#### Removed +- [digestive tract diverticulum](http://purl.obolibrary.org/obo/UBERON_0009854) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00100316" + +#### Added +- [digestive tract diverticulum](http://purl.obolibrary.org/obo/UBERON_0009854) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00100316" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### digestive tract epithelium `http://purl.obolibrary.org/obo/UBERON_0003929` +#### Removed +- [digestive tract epithelium](http://purl.obolibrary.org/obo/UBERON_0003929) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00047166" + +#### Added +- [digestive tract epithelium](http://purl.obolibrary.org/obo/UBERON_0003929) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00047166" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### dilatator pupillae `http://purl.obolibrary.org/obo/UBERON_0001608` +#### Removed +- [dilatator pupillae](http://purl.obolibrary.org/obo/UBERON_0001608) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "musculus dilatator pupillae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:49158" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [dilatator pupillae](http://purl.obolibrary.org/obo/UBERON_0001608) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "musculus dilatator pupillae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Iris_dilator_muscle" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [dilatator pupillae](http://purl.obolibrary.org/obo/UBERON_0001608) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "musculus dilatator pupillae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:49158" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [dilatator pupillae](http://purl.obolibrary.org/obo/UBERON_0001608) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "musculus dilatator pupillae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Iris_dilator_muscle" + + +### disconnected anatomical group `http://purl.obolibrary.org/obo/UBERON_0034923` +#### Removed +- [disconnected anatomical group](http://purl.obolibrary.org/obo/UBERON_0034923) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007276" + +#### Added +- [disconnected anatomical group](http://purl.obolibrary.org/obo/UBERON_0034923) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007276" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### distal convoluted tubule `http://purl.obolibrary.org/obo/UBERON_0001292` +#### Removed +- [distal convoluted tubule](http://purl.obolibrary.org/obo/UBERON_0001292) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tubulus contortus distalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Distal_convoluted_tubule" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [distal convoluted tubule](http://purl.obolibrary.org/obo/UBERON_0001292) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tubulus convolutus distalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [distal convoluted tubule](http://purl.obolibrary.org/obo/UBERON_0001292) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tubulus convolutus distalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [distal convoluted tubule](http://purl.obolibrary.org/obo/UBERON_0001292) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tubulus contortus distalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Distal_convoluted_tubule" + + +### distal phalanx `http://purl.obolibrary.org/obo/UBERON_0004300` +#### Removed +- [distal phalanx](http://purl.obolibrary.org/obo/UBERON_0004300) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "phalanx distalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Distal_phalanges" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [distal phalanx](http://purl.obolibrary.org/obo/UBERON_0004300) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "phalanx distalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Distal_phalanges" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### distal phalanx of manus `http://purl.obolibrary.org/obo/UBERON_0003865` +#### Removed +- [distal phalanx of manus](http://purl.obolibrary.org/obo/UBERON_0003865) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "phalanx distalis manus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:75818" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [distal phalanx of manus](http://purl.obolibrary.org/obo/UBERON_0003865) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "phalanx distalis manus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:75818" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### distal phalanx of pes `http://purl.obolibrary.org/obo/UBERON_0003867` +#### Removed +- [distal phalanx of pes](http://purl.obolibrary.org/obo/UBERON_0003867) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "phalanx distalis pedis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:75830" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [distal phalanx of pes](http://purl.obolibrary.org/obo/UBERON_0003867) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "phalanx distalis pedis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:75830" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### distal straight tubule postmacula segment `http://purl.obolibrary.org/obo/UBERON_0006854` +#### Removed +- [distal straight tubule postmacula segment](http://purl.obolibrary.org/obo/UBERON_0006854) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "https://sourceforge.net/tracker/?func=detail&aid=3123598&group_id=76834&atid=1205376" + +#### Added +- [distal straight tubule postmacula segment](http://purl.obolibrary.org/obo/UBERON_0006854) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) "https://sourceforge.net/tracker/?func=detail&aid=3123598&group_id=76834&atid=1205376"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + + +### dopaminergic neuron `http://purl.obolibrary.org/obo/CL_0000700` + +#### Added +- [dopaminergic neuron](http://purl.obolibrary.org/obo/CL_0000700) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### dorsal aorta `http://purl.obolibrary.org/obo/UBERON_0005805` +#### Removed +- [dorsal aorta](http://purl.obolibrary.org/obo/UBERON_0005805) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "aorta dorsalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "XAO:0000051" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [dorsal aorta](http://purl.obolibrary.org/obo/UBERON_0005805) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "aortae dorsales" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Dorsal_aorta" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [dorsal aorta](http://purl.obolibrary.org/obo/UBERON_0005805) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "aortae dorsales" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Dorsal_aorta" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [dorsal aorta](http://purl.obolibrary.org/obo/UBERON_0005805) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "aorta dorsalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "XAO:0000051" + + +### dorsal cochlear nucleus `http://purl.obolibrary.org/obo/UBERON_0002829` +#### Removed +- [dorsal cochlear nucleus](http://purl.obolibrary.org/obo/UBERON_0002829) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus cochlearis posterior" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Dorsal_cochlear_nucleus" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [dorsal cochlear nucleus](http://purl.obolibrary.org/obo/UBERON_0002829) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus cochlearis dorsalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:721" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [dorsal cochlear nucleus](http://purl.obolibrary.org/obo/UBERON_0002829) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus cochlearis posterior" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Dorsal_cochlear_nucleus" + +- [dorsal cochlear nucleus](http://purl.obolibrary.org/obo/UBERON_0002829) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus cochlearis dorsalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:721" + + +### dorsal horn of spinal cord `http://purl.obolibrary.org/obo/UBERON_0002256` +#### Removed +- [dorsal horn of spinal cord](http://purl.obolibrary.org/obo/UBERON_0002256) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cornu posterius medullae spinalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Posterior_horn_of_spinal_cord" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [dorsal horn of spinal cord](http://purl.obolibrary.org/obo/UBERON_0002256) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "columna grisea posterior medullae spinalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:256530" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [dorsal horn of spinal cord](http://purl.obolibrary.org/obo/UBERON_0002256) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "columna grisea posterior medullae spinalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:256530" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [dorsal horn of spinal cord](http://purl.obolibrary.org/obo/UBERON_0002256) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cornu posterius medullae spinalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Posterior_horn_of_spinal_cord" + + +### dorsal lateral geniculate nucleus `http://purl.obolibrary.org/obo/UBERON_0002479` +#### Removed +- [dorsal lateral geniculate nucleus](http://purl.obolibrary.org/obo/UBERON_0002479) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nucleus dorsalis corporis geniculati lateralis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:62214" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [dorsal lateral geniculate nucleus](http://purl.obolibrary.org/obo/UBERON_0002479) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus corporis geniculati lateralis, pars dorsalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:353" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [dorsal lateral geniculate nucleus](http://purl.obolibrary.org/obo/UBERON_0002479) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "corpus geniculatum laterale (Hassler)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:353" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [dorsal lateral geniculate nucleus](http://purl.obolibrary.org/obo/UBERON_0002479) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus geniculatus lateralis dorsalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:353" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [dorsal lateral geniculate nucleus](http://purl.obolibrary.org/obo/UBERON_0002479) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "corpus geniculatum laterale (Hassler)" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:353" + +- [dorsal lateral geniculate nucleus](http://purl.obolibrary.org/obo/UBERON_0002479) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nucleus dorsalis corporis geniculati lateralis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:62214" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [dorsal lateral geniculate nucleus](http://purl.obolibrary.org/obo/UBERON_0002479) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus corporis geniculati lateralis, pars dorsalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:353" + +- [dorsal lateral geniculate nucleus](http://purl.obolibrary.org/obo/UBERON_0002479) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus geniculatus lateralis dorsalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:353" + + +### dorsal mesentery `http://purl.obolibrary.org/obo/UBERON_0002296` +#### Removed +- [dorsal mesentery](http://purl.obolibrary.org/obo/UBERON_0002296) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "mesenterium dorsale commune" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Dorsal_mesentery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [dorsal mesentery](http://purl.obolibrary.org/obo/UBERON_0002296) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "mesenterium dorsale commune" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Dorsal_mesentery" + + +### dorsal metatarsal vein `http://purl.obolibrary.org/obo/UBERON_0001549` +#### Removed +- [dorsal metatarsal vein](http://purl.obolibrary.org/obo/UBERON_0001549) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "venae metatarsales dorsales" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Dorsal_metatarsal_veins" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [dorsal metatarsal vein](http://purl.obolibrary.org/obo/UBERON_0001549) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "venae metatarsales dorsales" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Dorsal_metatarsal_veins" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### dorsal plus ventral thalamus `http://purl.obolibrary.org/obo/UBERON_0001897` +#### Removed +- [dorsal plus ventral thalamus](http://purl.obolibrary.org/obo/UBERON_0001897) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "thalamencephalon" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:300" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [dorsal plus ventral thalamus](http://purl.obolibrary.org/obo/UBERON_0001897) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "thalamus opticus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:300" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [dorsal plus ventral thalamus](http://purl.obolibrary.org/obo/UBERON_0001897) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "thalamus opticus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:300" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [dorsal plus ventral thalamus](http://purl.obolibrary.org/obo/UBERON_0001897) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "thalamencephalon" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:300" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### dorsal root ganglion `http://purl.obolibrary.org/obo/UBERON_0000044` +#### Removed +- [dorsal root ganglion](http://purl.obolibrary.org/obo/UBERON_0000044) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ganglion sensorium nervi spinalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0001264" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Dorsal_root_ganglion" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [dorsal root ganglion](http://purl.obolibrary.org/obo/UBERON_0000044) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D005727" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [LexicalMatching](https://w3id.org/semapv/vocab/LexicalMatching) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + +- [dorsal root ganglion](http://purl.obolibrary.org/obo/UBERON_0000044) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ganglion sensorium nervi spinalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0001264" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Dorsal_root_ganglion" + + +### dorsal root of spinal cord `http://purl.obolibrary.org/obo/UBERON_0002261` +#### Removed +- [dorsal root of spinal cord](http://purl.obolibrary.org/obo/UBERON_0002261) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "radix posterior" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Posterior_root_of_spinal_nerve" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [dorsal root of spinal cord](http://purl.obolibrary.org/obo/UBERON_0002261) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "radix posterior" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Posterior_root_of_spinal_nerve" + + +### dorsal thalamus `http://purl.obolibrary.org/obo/UBERON_0004703` +#### Removed +- [dorsal thalamus](http://purl.obolibrary.org/obo/UBERON_0004703) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "thalamus dorsalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0001365" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Thalamus" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [dorsal thalamus](http://purl.obolibrary.org/obo/UBERON_0004703) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "thalamus dorsalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0001365" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Thalamus" + + +### dorsal venous arch `http://purl.obolibrary.org/obo/UBERON_0008783` +#### Removed +- [dorsal venous arch](http://purl.obolibrary.org/obo/UBERON_0008783) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arcus venosus dorsalis pedis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Dorsal_venous_arch_of_the_foot" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [dorsal venous arch](http://purl.obolibrary.org/obo/UBERON_0008783) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arcus venosus dorsalis pedis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Dorsal_venous_arch_of_the_foot" + + +### double negative T regulatory cell `http://purl.obolibrary.org/obo/CL_0011024` + +#### Added +- [double negative T regulatory cell](http://purl.obolibrary.org/obo/CL_0011024) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### double negative thymocyte `http://purl.obolibrary.org/obo/CL_0002489` + +#### Added +- [double negative thymocyte](http://purl.obolibrary.org/obo/CL_0002489) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### double-positive, alpha-beta thymocyte `http://purl.obolibrary.org/obo/CL_0000809` + +#### Added +- [double-positive, alpha-beta thymocyte](http://purl.obolibrary.org/obo/CL_0000809) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### duct `http://purl.obolibrary.org/obo/UBERON_0000058` +#### Removed +- [duct](http://purl.obolibrary.org/obo/UBERON_0000058) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00100314" + +#### Added +- [duct](http://purl.obolibrary.org/obo/UBERON_0000058) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00100314" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### duct epithelial cell `http://purl.obolibrary.org/obo/CL_0000068` + +#### Added +- [duct epithelial cell](http://purl.obolibrary.org/obo/CL_0000068) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### duct of seminal vesicle `http://purl.obolibrary.org/obo/UBERON_0005903` +#### Removed +- [duct of seminal vesicle](http://purl.obolibrary.org/obo/UBERON_0005903) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ductus excretorius glandulae vesiculosae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:19473" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [duct of seminal vesicle](http://purl.obolibrary.org/obo/UBERON_0005903) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ductus excretorius glandulae vesiculosae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Excretory_duct_of_seminal_gland" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [duct of seminal vesicle](http://purl.obolibrary.org/obo/UBERON_0005903) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ductus excretorius glandulae vesiculosae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:19473" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [duct of seminal vesicle](http://purl.obolibrary.org/obo/UBERON_0005903) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ductus excretorius glandulae vesiculosae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Excretory_duct_of_seminal_gland" + + +### duodenal gland `http://purl.obolibrary.org/obo/UBERON_0001212` +#### Removed +- [duodenal gland](http://purl.obolibrary.org/obo/UBERON_0001212) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "glandula duodenales Brunneri" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0002376" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [duodenal gland](http://purl.obolibrary.org/obo/UBERON_0001212) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "glandula duodenales" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0002376" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [duodenal gland](http://purl.obolibrary.org/obo/UBERON_0001212) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "glandula duodenales Brunneri" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0002376" + +- [duodenal gland](http://purl.obolibrary.org/obo/UBERON_0001212) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "glandula duodenales" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0002376" + + +### duodenal papilla `http://purl.obolibrary.org/obo/UBERON_0004914` +#### Removed +- [duodenal papilla](http://purl.obolibrary.org/obo/UBERON_0004914) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "papilla duodeni" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Major_duodenal_papilla" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [duodenal papilla](http://purl.obolibrary.org/obo/UBERON_0004914) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "papilla duodeni" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Major_duodenal_papilla" + + +### duodeno-jejunal junction `http://purl.obolibrary.org/obo/UBERON_8410000` +#### Removed +- [duodeno-jejunal junction](http://purl.obolibrary.org/obo/UBERON_8410000) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "flexura duodenojejunalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Duodenojejunal_flexure" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [duodeno-jejunal junction](http://purl.obolibrary.org/obo/UBERON_8410000) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "flexura duodenojejunalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Duodenojejunal_flexure" + + +### duodenum glandular cell `http://purl.obolibrary.org/obo/CL_1001589` + +#### Added +- [duodenum glandular cell](http://purl.obolibrary.org/obo/CL_1001589) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### early T lineage precursor `http://purl.obolibrary.org/obo/CL_0002425` + +#### Added +- [early T lineage precursor](http://purl.obolibrary.org/obo/CL_0002425) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### early lymphoid progenitor `http://purl.obolibrary.org/obo/CL_0000936` + +#### Added +- [early lymphoid progenitor](http://purl.obolibrary.org/obo/CL_0000936) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### early pharyngeal endoderm `http://purl.obolibrary.org/obo/UBERON_0007690` +#### Removed +- [early pharyngeal endoderm](http://purl.obolibrary.org/obo/UBERON_0007690) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "http://dev.biologists.org/content/128/22/4573.full" + +#### Added +- [early pharyngeal endoderm](http://purl.obolibrary.org/obo/UBERON_0007690) [see also](http://www.w3.org/2000/01/rdf-schema#seeAlso) "http://dev.biologists.org/content/128/22/4573.full"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + + +### early pro-B cell `http://purl.obolibrary.org/obo/CL_0002046` + +#### Added +- [early pro-B cell](http://purl.obolibrary.org/obo/CL_0002046) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### early promyelocyte `http://purl.obolibrary.org/obo/CL_0002154` + +#### Added +- [early promyelocyte](http://purl.obolibrary.org/obo/CL_0002154) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### eccrine sweat gland `http://purl.obolibrary.org/obo/UBERON_0000423` +#### Removed +- [eccrine sweat gland](http://purl.obolibrary.org/obo/UBERON_0000423) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "glandula sudorifera merocrina" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Eccrine_sweat_gland" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [eccrine sweat gland](http://purl.obolibrary.org/obo/UBERON_0000423) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "glandula sudorifera eccrina" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Eccrine_sweat_gland" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [eccrine sweat gland](http://purl.obolibrary.org/obo/UBERON_0000423) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "glandula sudorifera eccrina" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Eccrine_sweat_gland" + +- [eccrine sweat gland](http://purl.obolibrary.org/obo/UBERON_0000423) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "glandula sudorifera merocrina" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Eccrine_sweat_gland" + + +### ectocervix `http://purl.obolibrary.org/obo/UBERON_0012249` +#### Removed +- [ectocervix](http://purl.obolibrary.org/obo/UBERON_0012249) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "portio vaginalis cervicis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0001850" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [ectocervix](http://purl.obolibrary.org/obo/UBERON_0012249) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "portio vaginalis cervicis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0001850" + + +### ectoderm `http://purl.obolibrary.org/obo/UBERON_0000924` +#### Removed +- [ectoderm](http://purl.obolibrary.org/obo/UBERON_0000924) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00000111" + +#### Added +- [ectoderm](http://purl.obolibrary.org/obo/UBERON_0000924) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00000111" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### effector CD4-positive, alpha-beta T cell `http://purl.obolibrary.org/obo/CL_0001044` + +#### Added +- [effector CD4-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0001044) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### effector CD8-positive, alpha-beta T cell `http://purl.obolibrary.org/obo/CL_0001050` + +#### Added +- [effector CD8-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0001050) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### effector memory CD4-positive, alpha-beta T cell `http://purl.obolibrary.org/obo/CL_0000905` + +#### Added +- [effector memory CD4-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000905) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### effector memory CD8-positive, alpha-beta T cell `http://purl.obolibrary.org/obo/CL_0000913` + +#### Added +- [effector memory CD8-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000913) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### effector memory CD8-positive, alpha-beta T cell, terminally differentiated `http://purl.obolibrary.org/obo/CL_0001062` + +#### Added +- [effector memory CD8-positive, alpha-beta T cell, terminally differentiated](http://purl.obolibrary.org/obo/CL_0001062) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### efferent duct `http://purl.obolibrary.org/obo/UBERON_0006946` +#### Removed +- [efferent duct](http://purl.obolibrary.org/obo/UBERON_0006946) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ductuli efferentes testis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Efferent_ducts" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [efferent duct](http://purl.obolibrary.org/obo/UBERON_0006946) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ductuli efferentes testis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Efferent_ducts" + + +### ejaculatory duct `http://purl.obolibrary.org/obo/UBERON_0000999` +#### Removed +- [ejaculatory duct](http://purl.obolibrary.org/obo/UBERON_0000999) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ductus ejaculatorii" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Ejaculatory_duct" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [ejaculatory duct](http://purl.obolibrary.org/obo/UBERON_0000999) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ductus ejaculatorii" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Ejaculatory_duct" + + +### elastic tissue `http://purl.obolibrary.org/obo/UBERON_0002521` +#### Removed +- [elastic tissue](http://purl.obolibrary.org/obo/UBERON_0002521) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "textus connectivus elasticus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [elastic tissue](http://purl.obolibrary.org/obo/UBERON_0002521) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "textus connectivus elasticus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### elbow `http://purl.obolibrary.org/obo/UBERON_0001461` +#### Removed +- [elbow](http://purl.obolibrary.org/obo/UBERON_0001461) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "articulatio cubiti" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Elbow" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [elbow](http://purl.obolibrary.org/obo/UBERON_0001461) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "articulatio cubiti" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Elbow" + + +### elbow joint `http://purl.obolibrary.org/obo/UBERON_0001490` +#### Removed +- [elbow joint](http://purl.obolibrary.org/obo/UBERON_0001490) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "articulatio cubiti" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [elbow joint](http://purl.obolibrary.org/obo/UBERON_0001490) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "articulatio cubiti" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### elicited macrophage `http://purl.obolibrary.org/obo/CL_0000861` + +#### Added +- [elicited macrophage](http://purl.obolibrary.org/obo/CL_0000861) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### embryo `http://purl.obolibrary.org/obo/UBERON_0000922` +#### Removed +- [embryo](http://purl.obolibrary.org/obo/UBERON_0000922) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00000052" + +- [embryo](http://purl.obolibrary.org/obo/UBERON_0000922) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IDOMAL:0000646" + - [contributor](http://purl.org/dc/terms/contributor) "https://orcid.org/0000-0003-4423-4370" + +#### Added +- [embryo](http://purl.obolibrary.org/obo/UBERON_0000922) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IDOMAL:0000646" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + - [author_id](https://w3id.org/sssom/author_id) [0000-0003-4423-4370](https://orcid.org/0000-0003-4423-4370) + +- [embryo](http://purl.obolibrary.org/obo/UBERON_0000922) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00000052" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### embryonic fibroblast `http://purl.obolibrary.org/obo/CL_2000042` + +#### Added +- [embryonic fibroblast](http://purl.obolibrary.org/obo/CL_2000042) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### embryonic head `http://purl.obolibrary.org/obo/UBERON_0008816` +#### Removed +- [embryonic head](http://purl.obolibrary.org/obo/UBERON_0008816) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00000155" + +#### Added +- [embryonic head](http://purl.obolibrary.org/obo/UBERON_0008816) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00000155" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### embryonic stem cell `http://purl.obolibrary.org/obo/CL_0002322` + +#### Added +- [embryonic stem cell](http://purl.obolibrary.org/obo/CL_0002322) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### embryonic structure `http://purl.obolibrary.org/obo/UBERON_0002050` +#### Removed +- [embryonic structure](http://purl.obolibrary.org/obo/UBERON_0002050) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00004208" + +#### Added +- [embryonic structure](http://purl.obolibrary.org/obo/UBERON_0002050) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00004208" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### embryonic tagma `http://purl.obolibrary.org/obo/UBERON_6000137` +#### Removed +- [embryonic tagma](http://purl.obolibrary.org/obo/UBERON_6000137) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00000137" + +#### Added +- [embryonic tagma](http://purl.obolibrary.org/obo/UBERON_6000137) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00000137" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### embryonic urethral groove `http://purl.obolibrary.org/obo/UBERON_0013241` +#### Removed +- [embryonic urethral groove](http://purl.obolibrary.org/obo/UBERON_0013241) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sulcus urethralis primarius" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Urethral_groove" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [embryonic urethral groove](http://purl.obolibrary.org/obo/UBERON_0013241) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sulcus urethralis primarius" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Urethral_groove" + + +### endocardial cell `http://purl.obolibrary.org/obo/CL_0002350` + +#### Added +- [endocardial cell](http://purl.obolibrary.org/obo/CL_0002350) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### endocardial cushion `http://purl.obolibrary.org/obo/UBERON_0002062` +#### Removed +- [endocardial cushion](http://purl.obolibrary.org/obo/UBERON_0002062) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D054089" + +#### Added +- [endocardial cushion](http://purl.obolibrary.org/obo/UBERON_0002062) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D054089" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [author_id](https://w3id.org/sssom/author_id) [0000-0001-9439-5346](https://orcid.org/0000-0001-9439-5346) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### endocrine cell `http://purl.obolibrary.org/obo/CL_0000163` + +#### Added +- [endocrine cell](http://purl.obolibrary.org/obo/CL_0000163) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### endocrine gland `http://purl.obolibrary.org/obo/UBERON_0002368` +#### Removed +- [endocrine gland](http://purl.obolibrary.org/obo/UBERON_0002368) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "glandulae endocrinae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Endocrine_gland" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [endocrine gland](http://purl.obolibrary.org/obo/UBERON_0002368) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "glandulae endocrinae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Endocrine_gland" + + +### endocrine pancreas `http://purl.obolibrary.org/obo/UBERON_0000016` + +#### Added +- [endocrine pancreas](http://purl.obolibrary.org/obo/UBERON_0000016) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D007515" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [LexicalMatching](https://w3id.org/semapv/vocab/LexicalMatching) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### endocrine system `http://purl.obolibrary.org/obo/UBERON_0000949` +#### Removed +- [endocrine system](http://purl.obolibrary.org/obo/UBERON_0000949) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005068" + +#### Added +- [endocrine system](http://purl.obolibrary.org/obo/UBERON_0000949) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005068" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### endoderm `http://purl.obolibrary.org/obo/UBERON_0000925` +#### Removed +- [endoderm](http://purl.obolibrary.org/obo/UBERON_0000925) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00000125" + +#### Added +- [endoderm](http://purl.obolibrary.org/obo/UBERON_0000925) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00000125" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### endometrial gland `http://purl.obolibrary.org/obo/UBERON_0002451` +#### Removed +- [endometrial gland](http://purl.obolibrary.org/obo/UBERON_0002451) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "glandulae uterinae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:71647" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [endometrial gland](http://purl.obolibrary.org/obo/UBERON_0002451) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "glandulae uterinae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Uterine_glands" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [endometrial gland](http://purl.obolibrary.org/obo/UBERON_0002451) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "glandulae uterinae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Uterine_glands" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [endometrial gland](http://purl.obolibrary.org/obo/UBERON_0002451) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "glandulae uterinae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:71647" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### endometrial lymphatic vessel `http://purl.obolibrary.org/obo/UBERON_8600042` + +#### Added +- [endometrial lymphatic vessel](http://purl.obolibrary.org/obo/UBERON_8600042) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "uberon" + +- [endometrial lymphatic vessel](http://purl.obolibrary.org/obo/UBERON_8600042) [id](http://www.geneontology.org/formats/oboInOwl#id) "UBERON:8600042" + +- [endometrial lymphatic vessel](http://purl.obolibrary.org/obo/UBERON_8600042) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A lymphatic vessel that is part of an endometrium." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:23054374" + +- [endometrial lymphatic vessel](http://purl.obolibrary.org/obo/UBERON_8600042) [date](http://purl.org/dc/terms/date) "2024-01-16T18:18:36Z"^^[dateTime](http://www.w3.org/2001/XMLSchema#dateTime) + +- [endometrial lymphatic vessel](http://purl.obolibrary.org/obo/UBERON_8600042) [contributor](http://purl.org/dc/terms/contributor) [0000-0001-6677-8489](https://orcid.org/0000-0001-6677-8489) + +- [endometrial lymphatic vessel](http://purl.obolibrary.org/obo/UBERON_8600042) [label](http://www.w3.org/2000/01/rdf-schema#label) "endometrial lymphatic vessel" + +- Class: [endometrial lymphatic vessel](http://purl.obolibrary.org/obo/UBERON_8600042) + +- [endometrial lymphatic vessel](http://purl.obolibrary.org/obo/UBERON_8600042) EquivalentTo [lymphatic vessel](http://purl.obolibrary.org/obo/UBERON_0001473) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [endometrium](http://purl.obolibrary.org/obo/UBERON_0001295)) + +- [endometrial lymphatic vessel](http://purl.obolibrary.org/obo/UBERON_8600042) SubClassOf [reproductive structure](http://purl.obolibrary.org/obo/UBERON_0005156) + +- [endometrial lymphatic vessel](http://purl.obolibrary.org/obo/UBERON_8600042) SubClassOf [lymphatic vessel](http://purl.obolibrary.org/obo/UBERON_0001473) + +- [endometrial lymphatic vessel](http://purl.obolibrary.org/obo/UBERON_8600042) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [endometrium](http://purl.obolibrary.org/obo/UBERON_0001295) + + +### endometrium `http://purl.obolibrary.org/obo/UBERON_0001295` +#### Removed +- [endometrium](http://purl.obolibrary.org/obo/UBERON_0001295) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica mucosa uteri" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Endometrium" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [endometrium](http://purl.obolibrary.org/obo/UBERON_0001295) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica mucosa uteri" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Endometrium" + + +### endosteal cell `http://purl.obolibrary.org/obo/CL_0002157` + +#### Added +- [endosteal cell](http://purl.obolibrary.org/obo/CL_0002157) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### endothelial cell `http://purl.obolibrary.org/obo/CL_0000115` + +#### Added +- [endothelial cell](http://purl.obolibrary.org/obo/CL_0000115) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### endothelial cell of artery `http://purl.obolibrary.org/obo/CL_1000413` + +#### Added +- [endothelial cell of artery](http://purl.obolibrary.org/obo/CL_1000413) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### endothelial cell of coronary artery `http://purl.obolibrary.org/obo/CL_2000018` + +#### Added +- [endothelial cell of coronary artery](http://purl.obolibrary.org/obo/CL_2000018) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### endothelial cell of hepatic sinusoid `http://purl.obolibrary.org/obo/CL_1000398` + +#### Added +- [endothelial cell of hepatic sinusoid](http://purl.obolibrary.org/obo/CL_1000398) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### endothelial cell of lymphatic vessel `http://purl.obolibrary.org/obo/CL_0002138` + +#### Added +- [endothelial cell of lymphatic vessel](http://purl.obolibrary.org/obo/CL_0002138) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### endothelial cell of pericentral hepatic sinusoid `http://purl.obolibrary.org/obo/CL_0019022` + +#### Added +- [endothelial cell of pericentral hepatic sinusoid](http://purl.obolibrary.org/obo/CL_0019022) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### endothelial cell of periportal hepatic sinusoid `http://purl.obolibrary.org/obo/CL_0019021` + +#### Added +- [endothelial cell of periportal hepatic sinusoid](http://purl.obolibrary.org/obo/CL_0019021) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### endothelial cell of placenta `http://purl.obolibrary.org/obo/CL_0009092` + +#### Added +- [endothelial cell of placenta](http://purl.obolibrary.org/obo/CL_0009092) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### endothelial cell of sinusoid `http://purl.obolibrary.org/obo/CL_0002262` + +#### Added +- [endothelial cell of sinusoid](http://purl.obolibrary.org/obo/CL_0002262) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### endothelial cell of uterus `http://purl.obolibrary.org/obo/CL_0009095` + +#### Added +- [endothelial cell of uterus](http://purl.obolibrary.org/obo/CL_0009095) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### endothelial cell of vascular tree `http://purl.obolibrary.org/obo/CL_0002139` + +#### Added +- [endothelial cell of vascular tree](http://purl.obolibrary.org/obo/CL_0002139) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### endothelial cell of venule `http://purl.obolibrary.org/obo/CL_1000414` + +#### Added +- [endothelial cell of venule](http://purl.obolibrary.org/obo/CL_1000414) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### endothelial stalk cell `http://purl.obolibrary.org/obo/CL_0002671` + +#### Added +- [endothelial stalk cell](http://purl.obolibrary.org/obo/CL_0002671) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### endothelial tip cell `http://purl.obolibrary.org/obo/CL_0000704` + +#### Added +- [endothelial tip cell](http://purl.obolibrary.org/obo/CL_0000704) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### endovascular extravillous trophoblast cell `http://purl.obolibrary.org/obo/CL_4033063` + +#### Added +- [endovascular extravillous trophoblast cell](http://purl.obolibrary.org/obo/CL_4033063) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "endovascular extravillous trophoblast" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:37630754" + +- [endovascular extravillous trophoblast cell](http://purl.obolibrary.org/obo/CL_4033063) [contributor](http://purl.org/dc/terms/contributor) [0000-0001-6677-8489](https://orcid.org/0000-0001-6677-8489) + +- [endovascular extravillous trophoblast cell](http://purl.obolibrary.org/obo/CL_4033063) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "Shortly after implantation, the endovascular extravillous trophoblast cells occlude the maternal spiral arteries, preventing premature oxygen delivery to the placental villi and reducing fetal oxidative stress." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:37630754" + +- [endovascular extravillous trophoblast cell](http://purl.obolibrary.org/obo/CL_4033063) [date](http://purl.org/dc/terms/date) "2024-01-08T15:43:32Z"^^[dateTime](http://www.w3.org/2001/XMLSchema#dateTime) + +- [endovascular extravillous trophoblast cell](http://purl.obolibrary.org/obo/CL_4033063) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A trophoblast cell that invades the maternal spiral arteries and replace the endothelial lining, remodeling the vessels and allowing for adequate blood transport into the placenta. An endovascular extravillous trophoblast cell differentiates from an extravillous trophoblast cell. In humans, this cell can be distinguished by the expression of CD56." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:37630754" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "doi:10.1007/978-3-030-84725-8" + +- [endovascular extravillous trophoblast cell](http://purl.obolibrary.org/obo/CL_4033063) [label](http://www.w3.org/2000/01/rdf-schema#label) "endovascular extravillous trophoblast cell" + +- [endovascular extravillous trophoblast cell](http://purl.obolibrary.org/obo/CL_4033063) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "endovascular trophoblast" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:11337369" + +- [endovascular extravillous trophoblast cell](http://purl.obolibrary.org/obo/CL_4033063) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "eEVT" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:37630754" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [abbreviation](http://purl.obolibrary.org/obo/OMO_0003000) + +- Class: [endovascular extravillous trophoblast cell](http://purl.obolibrary.org/obo/CL_4033063) + +- [endovascular extravillous trophoblast cell](http://purl.obolibrary.org/obo/CL_4033063) SubClassOf [trophoblast cell](http://purl.obolibrary.org/obo/CL_0000351) + +- [endovascular extravillous trophoblast cell](http://purl.obolibrary.org/obo/CL_4033063) SubClassOf [develops from](http://purl.obolibrary.org/obo/RO_0002202) some [extravillous trophoblast](http://purl.obolibrary.org/obo/CL_0008036) + + +### enteric ganglion `http://purl.obolibrary.org/obo/UBERON_0001809` +#### Removed +- [enteric ganglion](http://purl.obolibrary.org/obo/UBERON_0001809) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Enteric_ganglia" + + + +### enteric neuron `http://purl.obolibrary.org/obo/CL_0007011` + +#### Added +- [enteric neuron](http://purl.obolibrary.org/obo/CL_0007011) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### enteric plexus `http://purl.obolibrary.org/obo/UBERON_0000429` +#### Removed +- [enteric plexus](http://purl.obolibrary.org/obo/UBERON_0000429) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "plexus nervosus entericus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:77597" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [enteric plexus](http://purl.obolibrary.org/obo/UBERON_0000429) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "plexus nervosus entericus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:77597" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### enteric smooth muscle cell `http://purl.obolibrary.org/obo/CL_0002504` + +#### Added +- [enteric smooth muscle cell](http://purl.obolibrary.org/obo/CL_0002504) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### enterocyte `http://purl.obolibrary.org/obo/CL_0000584` + +#### Added +- [enterocyte](http://purl.obolibrary.org/obo/CL_0000584) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### enterocyte of colon `http://purl.obolibrary.org/obo/CL_1000347` + +#### Added +- [enterocyte of colon](http://purl.obolibrary.org/obo/CL_1000347) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### enterocyte of epithelium of large intestine `http://purl.obolibrary.org/obo/CL_0002071` + +#### Added +- [enterocyte of epithelium of large intestine](http://purl.obolibrary.org/obo/CL_0002071) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### enterocyte of epithelium of small intestine `http://purl.obolibrary.org/obo/CL_1000334` + +#### Added +- [enterocyte of epithelium of small intestine](http://purl.obolibrary.org/obo/CL_1000334) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### enterocyte of epithelium proper of ileum `http://purl.obolibrary.org/obo/CL_1000342` + +#### Added +- [enterocyte of epithelium proper of ileum](http://purl.obolibrary.org/obo/CL_1000342) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### enteroendocrine cell `http://purl.obolibrary.org/obo/CL_0000164` + +#### Added +- [enteroendocrine cell](http://purl.obolibrary.org/obo/CL_0000164) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### enteroendocrine cell of colon `http://purl.obolibrary.org/obo/CL_0009042` + +#### Added +- [enteroendocrine cell of colon](http://purl.obolibrary.org/obo/CL_0009042) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### enteroendocrine cell of small intestine `http://purl.obolibrary.org/obo/CL_0009006` + +#### Added +- [enteroendocrine cell of small intestine](http://purl.obolibrary.org/obo/CL_0009006) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### enucleate erythrocyte `http://purl.obolibrary.org/obo/CL_0000595` + +#### Added +- [enucleate erythrocyte](http://purl.obolibrary.org/obo/CL_0000595) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### enucleated reticulocyte `http://purl.obolibrary.org/obo/CL_0002422` + +#### Added +- [enucleated reticulocyte](http://purl.obolibrary.org/obo/CL_0002422) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### eosinophil `http://purl.obolibrary.org/obo/CL_0000771` + +#### Added +- [eosinophil](http://purl.obolibrary.org/obo/CL_0000771) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### ependymal cell `http://purl.obolibrary.org/obo/CL_0000065` + +#### Added +- [ependymal cell](http://purl.obolibrary.org/obo/CL_0000065) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### epiblast (generic) `http://purl.obolibrary.org/obo/UBERON_0002532` +#### Removed +- [epiblast (generic)](http://purl.obolibrary.org/obo/UBERON_0002532) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "epiblastus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Epiblast" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [epiblast (generic)](http://purl.obolibrary.org/obo/UBERON_0002532) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "epiblastus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Epiblast" + + +### epibranchial ganglion `http://purl.obolibrary.org/obo/UBERON_0009127` +#### Removed +- [epibranchial ganglion](http://purl.obolibrary.org/obo/UBERON_0009127) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0006250" + - [contributor](http://purl.org/dc/terms/contributor) "https://orcid.org/0000-0003-4423-4370" + +#### Added +- [epibranchial ganglion](http://purl.obolibrary.org/obo/UBERON_0009127) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0006250" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + - [author_id](https://w3id.org/sssom/author_id) [0000-0003-4423-4370](https://orcid.org/0000-0003-4423-4370) + + +### epicardial adipocyte `http://purl.obolibrary.org/obo/CL_1000309` + +#### Added +- [epicardial adipocyte](http://purl.obolibrary.org/obo/CL_1000309) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### epicranial aponeurosis `http://purl.obolibrary.org/obo/UBERON_0006661` +#### Removed +- [epicranial aponeurosis](http://purl.obolibrary.org/obo/UBERON_0006661) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "galea aponeurotica; aponeurosis epicranialis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Galea_aponeurotica" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [epicranial aponeurosis](http://purl.obolibrary.org/obo/UBERON_0006661) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "aponeurosis epicranialis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:46768" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [epicranial aponeurosis](http://purl.obolibrary.org/obo/UBERON_0006661) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "aponeurosis epicranialis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:46768" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [epicranial aponeurosis](http://purl.obolibrary.org/obo/UBERON_0006661) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "galea aponeurotica; aponeurosis epicranialis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Galea_aponeurotica" + + +### epidermal Langerhans cell `http://purl.obolibrary.org/obo/CL_0002457` + +#### Added +- [epidermal Langerhans cell](http://purl.obolibrary.org/obo/CL_0002457) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### epidermal cell `http://purl.obolibrary.org/obo/CL_0000362` + +#### Added +- [epidermal cell](http://purl.obolibrary.org/obo/CL_0000362) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### epidural space `http://purl.obolibrary.org/obo/UBERON_0003691` +#### Removed +- [epidural space](http://purl.obolibrary.org/obo/UBERON_0003691) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "spatium epidurale" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Epidural_space" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [epidural space](http://purl.obolibrary.org/obo/UBERON_0003691) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "spatium extradurale" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:71228" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [epidural space](http://purl.obolibrary.org/obo/UBERON_0003691) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cavum epidurale" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Epidural_space" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [epidural space](http://purl.obolibrary.org/obo/UBERON_0003691) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cavum extradurale" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Epidural_space" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [epidural space](http://purl.obolibrary.org/obo/UBERON_0003691) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "spatium extradurale" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:71228" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [epidural space](http://purl.obolibrary.org/obo/UBERON_0003691) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "spatium epidurale" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Epidural_space" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [epidural space](http://purl.obolibrary.org/obo/UBERON_0003691) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cavum extradurale" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Epidural_space" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [epidural space](http://purl.obolibrary.org/obo/UBERON_0003691) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cavum epidurale" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Epidural_space" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### epinephrine binding `http://purl.obolibrary.org/obo/GO_0051379` +#### Removed +- [epinephrine binding](http://purl.obolibrary.org/obo/GO_0051379) SubClassOf [binding](http://purl.obolibrary.org/obo/GO_0005488) + +#### Added +- [epinephrine binding](http://purl.obolibrary.org/obo/GO_0051379) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) "https://github.com/geneontology/go-ontology/issues/21211"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + +- [epinephrine binding](http://purl.obolibrary.org/obo/GO_0051379) SubClassOf [hormone binding](http://purl.obolibrary.org/obo/GO_0042562) + + +### epithalamus `http://purl.obolibrary.org/obo/UBERON_0001899` +#### Removed +- [epithalamus](http://purl.obolibrary.org/obo/UBERON_0001899) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "epithalamus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Epithalamus" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [epithalamus](http://purl.obolibrary.org/obo/UBERON_0001899) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "epithalamus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Epithalamus" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### epithelial cell `http://purl.obolibrary.org/obo/CL_0000066` + +#### Added +- [epithelial cell](http://purl.obolibrary.org/obo/CL_0000066) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### epithelial cell of alveolus of lung `http://purl.obolibrary.org/obo/CL_0010003` + +#### Added +- [epithelial cell of alveolus of lung](http://purl.obolibrary.org/obo/CL_0010003) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### epithelial cell of esophagus `http://purl.obolibrary.org/obo/CL_0002252` + +#### Added +- [epithelial cell of esophagus](http://purl.obolibrary.org/obo/CL_0002252) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### epithelial cell of exocrine pancreas `http://purl.obolibrary.org/obo/CL_1001433` + +#### Added +- [epithelial cell of exocrine pancreas](http://purl.obolibrary.org/obo/CL_1001433) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### epithelial cell of glomerular capsule `http://purl.obolibrary.org/obo/CL_1000450` + +#### Added +- [epithelial cell of glomerular capsule](http://purl.obolibrary.org/obo/CL_1000450) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### epithelial cell of lacrimal sac `http://purl.obolibrary.org/obo/CL_1000436` + +#### Added +- [epithelial cell of lacrimal sac](http://purl.obolibrary.org/obo/CL_1000436) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### epithelial cell of large intestine `http://purl.obolibrary.org/obo/CL_0002253` + +#### Added +- [epithelial cell of large intestine](http://purl.obolibrary.org/obo/CL_0002253) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### epithelial cell of lower respiratory tract `http://purl.obolibrary.org/obo/CL_0002632` + +#### Added +- [epithelial cell of lower respiratory tract](http://purl.obolibrary.org/obo/CL_0002632) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### epithelial cell of lung `http://purl.obolibrary.org/obo/CL_0000082` + +#### Added +- [epithelial cell of lung](http://purl.obolibrary.org/obo/CL_0000082) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### epithelial cell of nephron `http://purl.obolibrary.org/obo/CL_1000449` + +#### Added +- [epithelial cell of nephron](http://purl.obolibrary.org/obo/CL_1000449) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### epithelial cell of prostate `http://purl.obolibrary.org/obo/CL_0002231` + +#### Added +- [epithelial cell of prostate](http://purl.obolibrary.org/obo/CL_0002231) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### epithelial cell of proximal tubule `http://purl.obolibrary.org/obo/CL_0002306` + +#### Added +- [epithelial cell of proximal tubule](http://purl.obolibrary.org/obo/CL_0002306) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### epithelial cell of proximal tubule segment 1 `http://purl.obolibrary.org/obo/CL_4030009` + +#### Added +- [epithelial cell of proximal tubule segment 1](http://purl.obolibrary.org/obo/CL_4030009) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### epithelial cell of proximal tubule segment 3 `http://purl.obolibrary.org/obo/CL_4030011` + +#### Added +- [epithelial cell of proximal tubule segment 3](http://purl.obolibrary.org/obo/CL_4030011) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### epithelial cell of small intestine `http://purl.obolibrary.org/obo/CL_0002254` + +#### Added +- [epithelial cell of small intestine](http://purl.obolibrary.org/obo/CL_0002254) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### epithelial cell of stratum germinativum of esophagus `http://purl.obolibrary.org/obo/CL_1000447` + +#### Added +- [epithelial cell of stratum germinativum of esophagus](http://purl.obolibrary.org/obo/CL_1000447) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### epithelial cell of sweat gland `http://purl.obolibrary.org/obo/CL_1000448` + +#### Added +- [epithelial cell of sweat gland](http://purl.obolibrary.org/obo/CL_1000448) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### epithelial cell of thymus `http://purl.obolibrary.org/obo/CL_0002293` + +#### Added +- [epithelial cell of thymus](http://purl.obolibrary.org/obo/CL_0002293) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### epithelial cell of urethra `http://purl.obolibrary.org/obo/CL_1000296` + +#### Added +- [epithelial cell of urethra](http://purl.obolibrary.org/obo/CL_1000296) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### epithelial cell of uterus `http://purl.obolibrary.org/obo/CL_0002149` + +#### Added +- [epithelial cell of uterus](http://purl.obolibrary.org/obo/CL_0002149) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### epithelial fate stem cell `http://purl.obolibrary.org/obo/CL_0000036` + +#### Added +- [epithelial fate stem cell](http://purl.obolibrary.org/obo/CL_0000036) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### epithelial tube `http://purl.obolibrary.org/obo/UBERON_0003914` +#### Removed +- [epithelial tube](http://purl.obolibrary.org/obo/UBERON_0003914) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007474" + +#### Added +- [epithelial tube](http://purl.obolibrary.org/obo/UBERON_0003914) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007474" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### epithelium `http://purl.obolibrary.org/obo/UBERON_0000483` +#### Removed +- [epithelium](http://purl.obolibrary.org/obo/UBERON_0000483) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007005" + +#### Added +- [epithelium](http://purl.obolibrary.org/obo/UBERON_0000483) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007005" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### epithelium of lens `http://purl.obolibrary.org/obo/UBERON_0001803` +#### Removed +- [epithelium of lens](http://purl.obolibrary.org/obo/UBERON_0001803) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "epithelium lentis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:58871" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [epithelium of lens](http://purl.obolibrary.org/obo/UBERON_0001803) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "epithelium lentis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:58871" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### erythroblast `http://purl.obolibrary.org/obo/CL_0000765` + +#### Added +- [erythroblast](http://purl.obolibrary.org/obo/CL_0000765) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### erythrocyte `http://purl.obolibrary.org/obo/CL_0000232` + +#### Added +- [erythrocyte](http://purl.obolibrary.org/obo/CL_0000232) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### erythroid lineage cell `http://purl.obolibrary.org/obo/CL_0000764` + +#### Added +- [erythroid lineage cell](http://purl.obolibrary.org/obo/CL_0000764) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### erythroid progenitor cell `http://purl.obolibrary.org/obo/CL_0000038` + +#### Added +- [erythroid progenitor cell](http://purl.obolibrary.org/obo/CL_0000038) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### erythroid progenitor cell, mammalian `http://purl.obolibrary.org/obo/CL_0001066` + +#### Added +- [erythroid progenitor cell, mammalian](http://purl.obolibrary.org/obo/CL_0001066) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### esophagus mucosa `http://purl.obolibrary.org/obo/UBERON_0002469` +#### Removed +- [esophagus mucosa](http://purl.obolibrary.org/obo/UBERON_0002469) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D000071041" + +- [esophagus mucosa](http://purl.obolibrary.org/obo/UBERON_0002469) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lamina muscularis mucosae oesophageae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:62996" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [esophagus mucosa](http://purl.obolibrary.org/obo/UBERON_0002469) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica mucosa oesophageae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:62996" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [esophagus mucosa](http://purl.obolibrary.org/obo/UBERON_0002469) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lamina muscularis mucosae oesophageae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:62996" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [esophagus mucosa](http://purl.obolibrary.org/obo/UBERON_0002469) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D000071041" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [author_id](https://w3id.org/sssom/author_id) [0000-0001-9439-5346](https://orcid.org/0000-0001-9439-5346) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + +- [esophagus mucosa](http://purl.obolibrary.org/obo/UBERON_0002469) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica mucosa oesophageae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:62996" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### establishment or maintenance of cell polarity `http://purl.obolibrary.org/obo/GO_0007163` +#### Removed +- [establishment or maintenance of cell polarity](http://purl.obolibrary.org/obo/GO_0007163) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [prokaryote_subset](http://purl.obolibrary.org/obo/go#prokaryote_subset) + +#### Added +- [establishment or maintenance of cell polarity](http://purl.obolibrary.org/obo/GO_0007163) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_prokaryote](http://purl.obolibrary.org/obo/go#goslim_prokaryote) + + +### ethmoid bone `http://purl.obolibrary.org/obo/UBERON_0001679` +#### Removed +- [ethmoid bone](http://purl.obolibrary.org/obo/UBERON_0001679) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "os ethmoidale" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Ethmoid" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:52740" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [ethmoid bone](http://purl.obolibrary.org/obo/UBERON_0001679) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "os ethmoidale" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Ethmoid" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:52740" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### ethmoid foramen `http://purl.obolibrary.org/obo/UBERON_0018415` +#### Removed +- [ethmoid foramen](http://purl.obolibrary.org/obo/UBERON_0018415) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "foramina ethmoidalia" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [ethmoid foramen](http://purl.obolibrary.org/obo/UBERON_0018415) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "foramina ethmoidalia" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### eukaryotic cell `http://purl.obolibrary.org/obo/CL_0000255` + +#### Added +- [eukaryotic cell](http://purl.obolibrary.org/obo/CL_0000255) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### eurydendroid cell `http://purl.obolibrary.org/obo/CL_0000253` + +#### Added +- [eurydendroid cell](http://purl.obolibrary.org/obo/CL_0000253) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### excretory duct `http://purl.obolibrary.org/obo/UBERON_0035050` + +#### Added +- [excretory duct](http://purl.obolibrary.org/obo/UBERON_0035050) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0006341" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + - [author_id](https://w3id.org/sssom/author_id) [0000-0003-4423-4370](https://orcid.org/0000-0003-4423-4370) + + +### excretory system `http://purl.obolibrary.org/obo/UBERON_8450002` +#### Removed +- [excretory system](http://purl.obolibrary.org/obo/UBERON_8450002) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0006338" + - [contributor](http://purl.org/dc/terms/contributor) "https://orcid.org/0000-0003-4423-4370" + +#### Added +- [excretory system](http://purl.obolibrary.org/obo/UBERON_8450002) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0006338" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + - [author_id](https://w3id.org/sssom/author_id) [0000-0003-4423-4370](https://orcid.org/0000-0003-4423-4370) + + +### exhausted T cell `http://purl.obolibrary.org/obo/CL_0011025` + +#### Added +- [exhausted T cell](http://purl.obolibrary.org/obo/CL_0011025) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### exocrine gland `http://purl.obolibrary.org/obo/UBERON_0002365` +#### Removed +- [exocrine gland](http://purl.obolibrary.org/obo/UBERON_0002365) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "glandula exocrina" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Exocrine_gland" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [exocrine gland](http://purl.obolibrary.org/obo/UBERON_0002365) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "glandula exocrina" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Exocrine_gland" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### exocrine pancreas `http://purl.obolibrary.org/obo/UBERON_0000017` +#### Removed +- [exocrine pancreas](http://purl.obolibrary.org/obo/UBERON_0000017) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D046790" + +#### Added +- [exocrine pancreas](http://purl.obolibrary.org/obo/UBERON_0000017) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D046790" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [author_id](https://w3id.org/sssom/author_id) [0000-0001-9439-5346](https://orcid.org/0000-0001-9439-5346) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### external carotid artery `http://purl.obolibrary.org/obo/UBERON_0001070` +#### Removed +- [external carotid artery](http://purl.obolibrary.org/obo/UBERON_0001070) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria carotis externa" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:External_carotid_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [external carotid artery](http://purl.obolibrary.org/obo/UBERON_0001070) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria carotis externa" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:External_carotid_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### external ectoderm `http://purl.obolibrary.org/obo/UBERON_0000076` +#### Removed +- [external ectoderm](http://purl.obolibrary.org/obo/UBERON_0000076) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0006242" + - [contributor](http://purl.org/dc/terms/contributor) "https://orcid.org/0000-0003-4423-4370" + +#### Added +- [external ectoderm](http://purl.obolibrary.org/obo/UBERON_0000076) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0006242" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + - [author_id](https://w3id.org/sssom/author_id) [0000-0003-4423-4370](https://orcid.org/0000-0003-4423-4370) + + +### external iliac artery `http://purl.obolibrary.org/obo/UBERON_0001308` +#### Removed +- [external iliac artery](http://purl.obolibrary.org/obo/UBERON_0001308) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria iliaca externa" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:External_iliac_artery" + +#### Added +- [external iliac artery](http://purl.obolibrary.org/obo/UBERON_0001308) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria iliaca externa" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:External_iliac_artery" + + +### external iliac vein `http://purl.obolibrary.org/obo/UBERON_0001316` +#### Removed +- [external iliac vein](http://purl.obolibrary.org/obo/UBERON_0001316) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vena iliaca externa" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:External_iliac_vein" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [external iliac vein](http://purl.obolibrary.org/obo/UBERON_0001316) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vena iliaca externa" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:External_iliac_vein" + + +### extracellular matrix `http://purl.obolibrary.org/obo/GO_0031012` +#### Removed +- [extracellular matrix](http://purl.obolibrary.org/obo/GO_0031012) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [prokaryote_subset](http://purl.obolibrary.org/obo/go#prokaryote_subset) + +#### Added +- [extracellular matrix](http://purl.obolibrary.org/obo/GO_0031012) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_prokaryote](http://purl.obolibrary.org/obo/go#goslim_prokaryote) + + +### extracellular region `http://purl.obolibrary.org/obo/GO_0005576` +#### Removed +- [extracellular region](http://purl.obolibrary.org/obo/GO_0005576) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [prokaryote_subset](http://purl.obolibrary.org/obo/go#prokaryote_subset) + +#### Added +- [extracellular region](http://purl.obolibrary.org/obo/GO_0005576) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_prokaryote](http://purl.obolibrary.org/obo/go#goslim_prokaryote) + + +### extracellular space `http://purl.obolibrary.org/obo/GO_0005615` +#### Removed +- [extracellular space](http://purl.obolibrary.org/obo/GO_0005615) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [prokaryote_subset](http://purl.obolibrary.org/obo/go#prokaryote_subset) + +#### Added +- [extracellular space](http://purl.obolibrary.org/obo/GO_0005615) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_prokaryote](http://purl.obolibrary.org/obo/go#goslim_prokaryote) + + +### extracellular structure organization `http://purl.obolibrary.org/obo/GO_0043062` +#### Removed +- [extracellular structure organization](http://purl.obolibrary.org/obo/GO_0043062) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [prokaryote_subset](http://purl.obolibrary.org/obo/go#prokaryote_subset) + +#### Added +- [extracellular structure organization](http://purl.obolibrary.org/obo/GO_0043062) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_prokaryote](http://purl.obolibrary.org/obo/go#goslim_prokaryote) + + +### extraembryonic membrane `http://purl.obolibrary.org/obo/UBERON_0005631` +#### Removed +- [extraembryonic membrane](http://purl.obolibrary.org/obo/UBERON_0005631) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D005321" + +#### Added +- [extraembryonic membrane](http://purl.obolibrary.org/obo/UBERON_0005631) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D005321" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [author_id](https://w3id.org/sssom/author_id) [0000-0001-9439-5346](https://orcid.org/0000-0001-9439-5346) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### extraembryonic mesoderm `http://purl.obolibrary.org/obo/UBERON_0005728` +#### Removed +- [extraembryonic mesoderm](http://purl.obolibrary.org/obo/UBERON_0005728) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "http://www.ana.ed.ac.uk/database/humat/notes/extraemb/mesoder.htm" + + + +### extraembryonic structure `http://purl.obolibrary.org/obo/UBERON_0000478` +#### Removed +- [extraembryonic structure](http://purl.obolibrary.org/obo/UBERON_0000478) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005835" + +#### Added +- [extraembryonic structure](http://purl.obolibrary.org/obo/UBERON_0000478) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005835" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### extravillous trophoblast `http://purl.obolibrary.org/obo/CL_0008036` + +#### Added +- [extravillous trophoblast](http://purl.obolibrary.org/obo/CL_0008036) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### eye `http://purl.obolibrary.org/obo/UBERON_0000970` +#### Removed +- [eye](http://purl.obolibrary.org/obo/UBERON_0000970) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005162" + +#### Added +- [eye](http://purl.obolibrary.org/obo/UBERON_0000970) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005162" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### eye photoreceptor cell `http://purl.obolibrary.org/obo/CL_0000287` + +#### Added +- [eye photoreceptor cell](http://purl.obolibrary.org/obo/CL_0000287) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### eye trabecular meshwork `http://purl.obolibrary.org/obo/UBERON_0005969` +#### Removed +- [eye trabecular meshwork](http://purl.obolibrary.org/obo/UBERON_0005969) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "reticulum trabeculare sclerae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Trabecular_meshwork" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [eye trabecular meshwork](http://purl.obolibrary.org/obo/UBERON_0005969) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "reticulum trabeculare sclerae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Trabecular_meshwork" + + +### face `http://purl.obolibrary.org/obo/UBERON_0001456` +#### Removed +- [face](http://purl.obolibrary.org/obo/UBERON_0001456) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "facia/facies" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Face" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [face](http://purl.obolibrary.org/obo/UBERON_0001456) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "facia/facies" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Face" + + +### facial artery `http://purl.obolibrary.org/obo/UBERON_0001612` +#### Removed +- [facial artery](http://purl.obolibrary.org/obo/UBERON_0001612) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria maxillaris externa" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Facial_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [facial artery](http://purl.obolibrary.org/obo/UBERON_0001612) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria maxillaris externa" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Facial_artery" + + +### facial bone `http://purl.obolibrary.org/obo/UBERON_0003462` +#### Removed +- [facial bone](http://purl.obolibrary.org/obo/UBERON_0003462) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D005147" + +#### Added +- [facial bone](http://purl.obolibrary.org/obo/UBERON_0003462) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D005147" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [author_id](https://w3id.org/sssom/author_id) [0000-0001-9439-5346](https://orcid.org/0000-0001-9439-5346) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### facial muscle `http://purl.obolibrary.org/obo/UBERON_0001577` +#### Removed +- [facial muscle](http://purl.obolibrary.org/obo/UBERON_0001577) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "musculi faciei" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Facial_muscles" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [facial muscle](http://purl.obolibrary.org/obo/UBERON_0001577) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "musculi faciei" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Facial_muscles" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### facial nerve `http://purl.obolibrary.org/obo/UBERON_0001647` +#### Removed +- [facial nerve](http://purl.obolibrary.org/obo/UBERON_0001647) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nervus facialis [vii]" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:50868" + +- [facial nerve](http://purl.obolibrary.org/obo/UBERON_0001647) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nervus facialis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Facial_nerve" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [facial nerve](http://purl.obolibrary.org/obo/UBERON_0001647) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nervus facialis [vii]" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:50868" + +- [facial nerve](http://purl.obolibrary.org/obo/UBERON_0001647) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nervus facialis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Facial_nerve" + + +### facial nerve canal `http://purl.obolibrary.org/obo/UBERON_0018413` +#### Removed +- [facial nerve canal](http://purl.obolibrary.org/obo/UBERON_0018413) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "canalis nervi facialis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:54952" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [facial nerve canal](http://purl.obolibrary.org/obo/UBERON_0018413) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "canalis nervi facialis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:54952" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### facial nerve root `http://purl.obolibrary.org/obo/UBERON_0004674` +#### Removed +- [facial nerve root](http://purl.obolibrary.org/obo/UBERON_0004674) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "fibrae nervi facialis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:53418" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [facial nerve root](http://purl.obolibrary.org/obo/UBERON_0004674) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "fibrae nervi facialis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:53418" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### facial skeleton `http://purl.obolibrary.org/obo/UBERON_0011156` +#### Removed +- [facial skeleton](http://purl.obolibrary.org/obo/UBERON_0011156) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ossa faciei" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Facial_skeleton" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [facial skeleton](http://purl.obolibrary.org/obo/UBERON_0011156) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ossa facialia" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Facial_skeleton" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [facial skeleton](http://purl.obolibrary.org/obo/UBERON_0011156) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ossa faciei" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Facial_skeleton" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [facial skeleton](http://purl.obolibrary.org/obo/UBERON_0011156) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ossa facialia" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Facial_skeleton" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### facial vein `http://purl.obolibrary.org/obo/UBERON_0001653` +#### Removed +- [facial vein](http://purl.obolibrary.org/obo/UBERON_0001653) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vena facialis anterior" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Facial_vein" + +#### Added +- [facial vein](http://purl.obolibrary.org/obo/UBERON_0001653) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vena facialis anterior" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Facial_vein" + + +### falciform ligament `http://purl.obolibrary.org/obo/UBERON_0001247` +#### Removed +- [falciform ligament](http://purl.obolibrary.org/obo/UBERON_0001247) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ligamentum falciforme hepatis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:15823" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [falciform ligament](http://purl.obolibrary.org/obo/UBERON_0001247) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ligamentum falciforme hepatis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:15823" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### fallopian tube `http://purl.obolibrary.org/obo/UBERON_0003889` +#### Removed +- [fallopian tube](http://purl.obolibrary.org/obo/UBERON_0003889) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tuba uterina" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Fallopian_tube" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [fallopian tube](http://purl.obolibrary.org/obo/UBERON_0003889) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tuba uterina" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Fallopian_tube" + + +### fast muscle cell `http://purl.obolibrary.org/obo/CL_0000190` + +#### Added +- [fast muscle cell](http://purl.obolibrary.org/obo/CL_0000190) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### feces `http://purl.obolibrary.org/obo/UBERON_0001988` +#### Removed +- [feces](http://purl.obolibrary.org/obo/UBERON_0001988) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "portionem cacas" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [feces](http://purl.obolibrary.org/obo/UBERON_0001988) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "portionem cacas" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### female germ cell `http://purl.obolibrary.org/obo/CL_0000021` + +#### Added +- [female germ cell](http://purl.obolibrary.org/obo/CL_0000021) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### female organism `http://purl.obolibrary.org/obo/UBERON_0003100` +#### Removed +- [female organism](http://purl.obolibrary.org/obo/UBERON_0003100) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007011" + +#### Added +- [female organism](http://purl.obolibrary.org/obo/UBERON_0003100) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007011" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### female reproductive system `http://purl.obolibrary.org/obo/UBERON_0000474` +#### Removed +- [female reproductive system](http://purl.obolibrary.org/obo/UBERON_0000474) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00004864" + +#### Added +- [female reproductive system](http://purl.obolibrary.org/obo/UBERON_0000474) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [human_reference_atlas](http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas) + +- [female reproductive system](http://purl.obolibrary.org/obo/UBERON_0000474) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00004864" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + +- [female reproductive system](http://purl.obolibrary.org/obo/UBERON_0000474) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606) + + +### female urethral meatus `http://purl.obolibrary.org/obo/UBERON_0006565` +#### Removed +- [female urethral meatus](http://purl.obolibrary.org/obo/UBERON_0006565) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ostium urethrae externum (urethra feminina)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:85266" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [female urethral meatus](http://purl.obolibrary.org/obo/UBERON_0006565) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ostium urethrae externum (urethra feminina)" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:85266" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### femoral artery `http://purl.obolibrary.org/obo/UBERON_0002060` +#### Removed +- [femoral artery](http://purl.obolibrary.org/obo/UBERON_0002060) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria femoralis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Femoral_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [femoral artery](http://purl.obolibrary.org/obo/UBERON_0002060) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria femoralis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Femoral_artery" + + +### femoral vein `http://purl.obolibrary.org/obo/UBERON_0001361` +#### Removed +- [femoral vein](http://purl.obolibrary.org/obo/UBERON_0001361) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vena femoralis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Femoral_vein" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [femoral vein](http://purl.obolibrary.org/obo/UBERON_0001361) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vena femoralis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Femoral_vein" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### femur `http://purl.obolibrary.org/obo/UBERON_0000981` +#### Removed +- [femur](http://purl.obolibrary.org/obo/UBERON_0000981) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "os femorale" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0001284" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [femur](http://purl.obolibrary.org/obo/UBERON_0000981) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "os femoris" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0001284" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [femur](http://purl.obolibrary.org/obo/UBERON_0000981) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "os longissimum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Femur" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [femur](http://purl.obolibrary.org/obo/UBERON_0000981) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "os femoris" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0001284" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [femur](http://purl.obolibrary.org/obo/UBERON_0000981) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "os femorale" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0001284" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [femur](http://purl.obolibrary.org/obo/UBERON_0000981) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "os longissimum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Femur" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### fenestrated cell `http://purl.obolibrary.org/obo/CL_0000666` + +#### Added +- [fenestrated cell](http://purl.obolibrary.org/obo/CL_0000666) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### fetal cardiomyocyte `http://purl.obolibrary.org/obo/CL_0002495` + +#### Added +- [fetal cardiomyocyte](http://purl.obolibrary.org/obo/CL_0002495) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### fibro/adipogenic progenitor cell `http://purl.obolibrary.org/obo/CL_0009099` + +#### Added +- [fibro/adipogenic progenitor cell](http://purl.obolibrary.org/obo/CL_0009099) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### fibroblast `http://purl.obolibrary.org/obo/CL_0000057` + +#### Added +- [fibroblast](http://purl.obolibrary.org/obo/CL_0000057) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### fibroblast of breast `http://purl.obolibrary.org/obo/CL_4006000` + +#### Added +- [fibroblast of breast](http://purl.obolibrary.org/obo/CL_4006000) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### fibroblast of cardiac tissue `http://purl.obolibrary.org/obo/CL_0002548` + +#### Added +- [fibroblast of cardiac tissue](http://purl.obolibrary.org/obo/CL_0002548) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### fibroblast of connective tissue of glandular part of prostate `http://purl.obolibrary.org/obo/CL_1000305` + +#### Added +- [fibroblast of connective tissue of glandular part of prostate](http://purl.obolibrary.org/obo/CL_1000305) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### fibroblast of connective tissue of nonglandular part of prostate `http://purl.obolibrary.org/obo/CL_1000304` + +#### Added +- [fibroblast of connective tissue of nonglandular part of prostate](http://purl.obolibrary.org/obo/CL_1000304) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### fibroblast of connective tissue of prostate `http://purl.obolibrary.org/obo/CL_1000299` + +#### Added +- [fibroblast of connective tissue of prostate](http://purl.obolibrary.org/obo/CL_1000299) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### fibroblast of lung `http://purl.obolibrary.org/obo/CL_0002553` + +#### Added +- [fibroblast of lung](http://purl.obolibrary.org/obo/CL_0002553) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### fibroblast of mammary gland `http://purl.obolibrary.org/obo/CL_0002555` + +#### Added +- [fibroblast of mammary gland](http://purl.obolibrary.org/obo/CL_0002555) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### fibrocartilage `http://purl.obolibrary.org/obo/UBERON_0001995` +#### Removed +- [fibrocartilage](http://purl.obolibrary.org/obo/UBERON_0001995) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D051445" + +#### Added +- [fibrocartilage](http://purl.obolibrary.org/obo/UBERON_0001995) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D051445" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [author_id](https://w3id.org/sssom/author_id) [0000-0001-9439-5346](https://orcid.org/0000-0001-9439-5346) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### fibrocyte `http://purl.obolibrary.org/obo/CL_0000135` + +#### Added +- [fibrocyte](http://purl.obolibrary.org/obo/CL_0000135) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### fibrous joint `http://purl.obolibrary.org/obo/UBERON_0002209` +#### Removed +- [fibrous joint](http://purl.obolibrary.org/obo/UBERON_0002209) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "junctura fibrosa" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Fibrous_joint" + +#### Added +- [fibrous joint](http://purl.obolibrary.org/obo/UBERON_0002209) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "junctura fibrosa" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Fibrous_joint" + + +### fibrous pericardium `http://purl.obolibrary.org/obo/UBERON_0002359` +#### Removed +- [fibrous pericardium](http://purl.obolibrary.org/obo/UBERON_0002359) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "pericardium fibrosum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Fibrous_pericardium" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [fibrous pericardium](http://purl.obolibrary.org/obo/UBERON_0002359) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "pericardium fibrosum" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Fibrous_pericardium" + + +### fibrous ring of heart `http://purl.obolibrary.org/obo/UBERON_0006008` +#### Removed +- [fibrous ring of heart](http://purl.obolibrary.org/obo/UBERON_0006008) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "annulus fibrosus cordis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Fibrous_rings_of_heart" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [fibrous ring of heart](http://purl.obolibrary.org/obo/UBERON_0006008) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "annulus fibrosus cordis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Fibrous_rings_of_heart" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### flat bone `http://purl.obolibrary.org/obo/UBERON_0010428` +#### Removed +- [flat bone](http://purl.obolibrary.org/obo/UBERON_0010428) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "os planum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Flat_bone" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [flat bone](http://purl.obolibrary.org/obo/UBERON_0010428) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "os planum" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Flat_bone" + + +### follicular B cell `http://purl.obolibrary.org/obo/CL_0000843` + +#### Added +- [follicular B cell](http://purl.obolibrary.org/obo/CL_0000843) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### follicular antrum `http://purl.obolibrary.org/obo/UBERON_0000039` +#### Removed +- [follicular antrum](http://purl.obolibrary.org/obo/UBERON_0000039) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "antrum follicularum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Follicular_antrum" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [follicular antrum](http://purl.obolibrary.org/obo/UBERON_0000039) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "antrum follicularum" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Follicular_antrum" + + +### follicular dendritic cell `http://purl.obolibrary.org/obo/CL_0000442` + +#### Added +- [follicular dendritic cell](http://purl.obolibrary.org/obo/CL_0000442) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### follicular fluid `http://purl.obolibrary.org/obo/UBERON_0000038` +#### Removed +- [follicular fluid](http://purl.obolibrary.org/obo/UBERON_0000038) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "liquor folliculi" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [follicular fluid](http://purl.obolibrary.org/obo/UBERON_0000038) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "liquor folliculi" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Follicular_fluid" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [follicular fluid](http://purl.obolibrary.org/obo/UBERON_0000038) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "liquor folliculi" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Follicular_fluid" + +- [follicular fluid](http://purl.obolibrary.org/obo/UBERON_0000038) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "liquor folliculi" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### foramen magnum `http://purl.obolibrary.org/obo/UBERON_0003687` +#### Removed +- [foramen magnum](http://purl.obolibrary.org/obo/UBERON_0003687) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0006035" + - [contributor](http://purl.org/dc/terms/contributor) "https://orcid.org/0000-0003-4423-4370" + +#### Added +- [foramen magnum](http://purl.obolibrary.org/obo/UBERON_0003687) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0006035" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + - [author_id](https://w3id.org/sssom/author_id) [0000-0003-4423-4370](https://orcid.org/0000-0003-4423-4370) + + +### foramen rotundum `http://purl.obolibrary.org/obo/UBERON_0005446` +#### Removed +- [foramen rotundum](http://purl.obolibrary.org/obo/UBERON_0005446) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "foramen rotundum ossis sphenoidalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Foramen_rotundum" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [foramen rotundum](http://purl.obolibrary.org/obo/UBERON_0005446) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "foramen rotundum ossis sphenoidalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Foramen_rotundum" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### forebrain radial glial cell `http://purl.obolibrary.org/obo/CL_0013000` + +#### Added +- [forebrain radial glial cell](http://purl.obolibrary.org/obo/CL_0013000) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### foregut `http://purl.obolibrary.org/obo/UBERON_0001041` +#### Removed +- [foregut](http://purl.obolibrary.org/obo/UBERON_0001041) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "praeenteron" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Foregut" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [foregut](http://purl.obolibrary.org/obo/UBERON_0001041) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "proenteron" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Foregut" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [foregut](http://purl.obolibrary.org/obo/UBERON_0001041) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005379" + +#### Added +- [foregut](http://purl.obolibrary.org/obo/UBERON_0001041) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005379" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + +- [foregut](http://purl.obolibrary.org/obo/UBERON_0001041) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "proenteron" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Foregut" + +- [foregut](http://purl.obolibrary.org/obo/UBERON_0001041) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "praeenteron" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Foregut" + + +### forelimb `http://purl.obolibrary.org/obo/UBERON_0002102` +#### Removed +- [forelimb](http://purl.obolibrary.org/obo/UBERON_0002102) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "membrum superius" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:7183" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [forelimb](http://purl.obolibrary.org/obo/UBERON_0002102) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "membrum superius" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:7183" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### forelimb skeleton `http://purl.obolibrary.org/obo/UBERON_0001440` +#### Removed +- [forelimb skeleton](http://purl.obolibrary.org/obo/UBERON_0001440) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ossa membri superioris" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:24139" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [forelimb skeleton](http://purl.obolibrary.org/obo/UBERON_0001440) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ossa membri superioris" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:24139" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### forelimb stylopod `http://purl.obolibrary.org/obo/UBERON_0003822` +#### Removed +- [forelimb stylopod](http://purl.obolibrary.org/obo/UBERON_0003822) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regio brachialis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:24890" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [forelimb stylopod](http://purl.obolibrary.org/obo/UBERON_0003822) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regio brachialis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:24890" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### forelimb zeugopod `http://purl.obolibrary.org/obo/UBERON_0002386` +#### Removed +- [forelimb zeugopod](http://purl.obolibrary.org/obo/UBERON_0002386) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regio antebrachialis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:9663" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [forelimb zeugopod](http://purl.obolibrary.org/obo/UBERON_0002386) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "antebrachium" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Forearm" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [forelimb zeugopod](http://purl.obolibrary.org/obo/UBERON_0002386) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regio antebrachialis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:9663" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [forelimb zeugopod](http://purl.obolibrary.org/obo/UBERON_0002386) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "antebrachium" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Forearm" + + +### fornix of brain `http://purl.obolibrary.org/obo/UBERON_0000052` +#### Removed +- [fornix of brain](http://purl.obolibrary.org/obo/UBERON_0000052) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "fornix cerebri" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:268" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [fornix of brain](http://purl.obolibrary.org/obo/UBERON_0000052) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "fornix cerebri" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:268" + + +### fourth ventricle `http://purl.obolibrary.org/obo/UBERON_0002422` +#### Removed +- [fourth ventricle](http://purl.obolibrary.org/obo/UBERON_0002422) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ventriculus quartus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Fourth_ventricle" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [fourth ventricle](http://purl.obolibrary.org/obo/UBERON_0002422) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ventriculus quartus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Fourth_ventricle" + + +### foveolar cell of stomach `http://purl.obolibrary.org/obo/CL_0002179` + +#### Added +- [foveolar cell of stomach](http://purl.obolibrary.org/obo/CL_0002179) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### fraction A pre-pro B cell `http://purl.obolibrary.org/obo/CL_0002045` + +#### Added +- [fraction A pre-pro B cell](http://purl.obolibrary.org/obo/CL_0002045) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### frontal cortex `http://purl.obolibrary.org/obo/UBERON_0001870` + +#### Added +- [frontal cortex](http://purl.obolibrary.org/obo/UBERON_0001870) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D005625" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [LexicalMatching](https://w3id.org/semapv/vocab/LexicalMatching) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### frontal lobe `http://purl.obolibrary.org/obo/UBERON_0016525` +#### Removed +- [frontal lobe](http://purl.obolibrary.org/obo/UBERON_0016525) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lobi frontales" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:56" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [frontal lobe](http://purl.obolibrary.org/obo/UBERON_0016525) [has_broad_synonym](http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym) "regio frontalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:61824" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [frontal lobe](http://purl.obolibrary.org/obo/UBERON_0016525) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lobus frontalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Frontal_lobe" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [frontal lobe](http://purl.obolibrary.org/obo/UBERON_0016525) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lobi frontales" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:56" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [frontal lobe](http://purl.obolibrary.org/obo/UBERON_0016525) [has_broad_synonym](http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym) "regio frontalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:61824" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [frontal lobe](http://purl.obolibrary.org/obo/UBERON_0016525) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lobus frontalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Frontal_lobe" + + +### frontal suture `http://purl.obolibrary.org/obo/UBERON_0002490` +#### Removed +- [frontal suture](http://purl.obolibrary.org/obo/UBERON_0002490) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "sutura frontalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Frontal_suture" + +- [frontal suture](http://purl.obolibrary.org/obo/UBERON_0002490) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sutura metopica" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:52989" + +#### Added +- [frontal suture](http://purl.obolibrary.org/obo/UBERON_0002490) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sutura metopica" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:52989" + +- [frontal suture](http://purl.obolibrary.org/obo/UBERON_0002490) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "sutura frontalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Frontal_suture" + + +### frontonasal prominence `http://purl.obolibrary.org/obo/UBERON_0004066` +#### Removed +- [frontonasal prominence](http://purl.obolibrary.org/obo/UBERON_0004066) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "prominentia frontonasalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Frontonasal_prominence" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [frontonasal prominence](http://purl.obolibrary.org/obo/UBERON_0004066) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "prominentia frontonasalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Frontonasal_prominence" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### fundic gastric gland `http://purl.obolibrary.org/obo/UBERON_0010038` +#### Removed +- [fundic gastric gland](http://purl.obolibrary.org/obo/UBERON_0010038) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "glandulae gastricae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Fundic_glands" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [fundic gastric gland](http://purl.obolibrary.org/obo/UBERON_0010038) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "glandulae gastricae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Fundic_glands" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### fundus of urinary bladder `http://purl.obolibrary.org/obo/UBERON_0006082` +#### Removed +- [fundus of urinary bladder](http://purl.obolibrary.org/obo/UBERON_0006082) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "fundus vesicae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:15908" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [fundus of urinary bladder](http://purl.obolibrary.org/obo/UBERON_0006082) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "fundus vesicae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:15908" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### gallbladder `http://purl.obolibrary.org/obo/UBERON_0002110` +#### Removed +- [gallbladder](http://purl.obolibrary.org/obo/UBERON_0002110) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vesica fellea" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Gallbladder" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [gallbladder](http://purl.obolibrary.org/obo/UBERON_0002110) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vesica biliaris" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Gallbladder" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [gallbladder](http://purl.obolibrary.org/obo/UBERON_0002110) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vesica fellea" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Gallbladder" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [gallbladder](http://purl.obolibrary.org/obo/UBERON_0002110) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vesica biliaris" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Gallbladder" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### gallbladder serosa `http://purl.obolibrary.org/obo/UBERON_0004783` +#### Removed +- [gallbladder serosa](http://purl.obolibrary.org/obo/UBERON_0004783) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica serosa vesicae biliaris" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:14659" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [gallbladder serosa](http://purl.obolibrary.org/obo/UBERON_0004783) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica serosa vesicae biliaris" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:14659" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### gamma-delta T cell `http://purl.obolibrary.org/obo/CL_0000798` + +#### Added +- [gamma-delta T cell](http://purl.obolibrary.org/obo/CL_0000798) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### ganglion interneuron `http://purl.obolibrary.org/obo/CL_0000397` + +#### Added +- [ganglion interneuron](http://purl.obolibrary.org/obo/CL_0000397) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### ganglionic layer of retina `http://purl.obolibrary.org/obo/UBERON_0001792` +#### Removed +- [ganglionic layer of retina](http://purl.obolibrary.org/obo/UBERON_0001792) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "stratum ganglionicum retinae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Ganglion_cell_layer" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [ganglionic layer of retina](http://purl.obolibrary.org/obo/UBERON_0001792) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "stratum ganglionicum retinae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Ganglion_cell_layer" + + +### gas excreted from digestive tract `http://purl.obolibrary.org/obo/UBERON_0034946` +#### Removed +- [gas excreted from digestive tract](http://purl.obolibrary.org/obo/UBERON_0034946) [has narrow synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "flatus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Flatulence" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [gas excreted from digestive tract](http://purl.obolibrary.org/obo/UBERON_0034946) [has narrow synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "flatus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Flatulence" + + +### gastric juice `http://purl.obolibrary.org/obo/UBERON_0001971` +#### Removed +- [gastric juice](http://purl.obolibrary.org/obo/UBERON_0001971) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Gastric_juice" + + + +### gastroesophageal sphincter `http://purl.obolibrary.org/obo/UBERON_0004550` +#### Removed +- [gastroesophageal sphincter](http://purl.obolibrary.org/obo/UBERON_0004550) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "constrictor cardiae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MP:0010153" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [gastroesophageal sphincter](http://purl.obolibrary.org/obo/UBERON_0004550) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "constrictor cardiae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MP:0010153" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [gastroesophageal sphincter](http://purl.obolibrary.org/obo/UBERON_0004550) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D049630" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [LexicalMatching](https://w3id.org/semapv/vocab/LexicalMatching) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### gastrula `http://purl.obolibrary.org/obo/UBERON_0004734` +#### Removed +- [gastrula](http://purl.obolibrary.org/obo/UBERON_0004734) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005317" + +#### Added +- [gastrula](http://purl.obolibrary.org/obo/UBERON_0004734) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005317" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### generation of precursor metabolites and energy `http://purl.obolibrary.org/obo/GO_0006091` +#### Removed +- [generation of precursor metabolites and energy](http://purl.obolibrary.org/obo/GO_0006091) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [prokaryote_subset](http://purl.obolibrary.org/obo/go#prokaryote_subset) + +#### Added +- [generation of precursor metabolites and energy](http://purl.obolibrary.org/obo/GO_0006091) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_prokaryote](http://purl.obolibrary.org/obo/go#goslim_prokaryote) + + +### geniculate ganglion `http://purl.obolibrary.org/obo/UBERON_0001700` +#### Removed +- [geniculate ganglion](http://purl.obolibrary.org/obo/UBERON_0001700) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ganglion geniculi nervi facialis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Geniculate_ganglion" + +#### Added +- [geniculate ganglion](http://purl.obolibrary.org/obo/UBERON_0001700) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ganglion geniculi nervi facialis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Geniculate_ganglion" + + +### germ cell `http://purl.obolibrary.org/obo/CL_0000586` + +#### Added +- [germ cell](http://purl.obolibrary.org/obo/CL_0000586) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### germ layer `http://purl.obolibrary.org/obo/UBERON_0000923` +#### Removed +- [germ layer](http://purl.obolibrary.org/obo/UBERON_0000923) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00000110" + +#### Added +- [germ layer](http://purl.obolibrary.org/obo/UBERON_0000923) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00000110" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### germinal center B cell `http://purl.obolibrary.org/obo/CL_0000844` + +#### Added +- [germinal center B cell](http://purl.obolibrary.org/obo/CL_0000844) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### germline ring canal `http://purl.obolibrary.org/obo/GO_0045172` +#### Removed +- [germline ring canal](http://purl.obolibrary.org/obo/GO_0045172) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0045172" + +- [germline ring canal](http://purl.obolibrary.org/obo/GO_0045172) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "cellular_component" + +- [germline ring canal](http://purl.obolibrary.org/obo/GO_0045172) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Germline specific intercellular bridge. During cyst formation in insects, ring canals interconnect the cells of the cyst, facilitating the passage of cytoplasmic components between cells." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:9635420" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mtg_sensu" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:9655801" + +- [germline ring canal](http://purl.obolibrary.org/obo/GO_0045172) [label](http://www.w3.org/2000/01/rdf-schema#label) "germline ring canal" + +- Class: [germline ring canal](http://purl.obolibrary.org/obo/GO_0045172) + +- [germline ring canal](http://purl.obolibrary.org/obo/GO_0045172) SubClassOf [intercellular bridge](http://purl.obolibrary.org/obo/GO_0045171) + +- [germline ring canal](http://purl.obolibrary.org/obo/GO_0045172) SubClassOf [only in taxon](http://purl.obolibrary.org/obo/RO_0002160) some [Arthropoda](http://purl.obolibrary.org/obo/NCBITaxon_6656) + +- [germline ring canal](http://purl.obolibrary.org/obo/GO_0045172) SubClassOf [in taxon](http://purl.obolibrary.org/obo/RO_0002162) only [Arthropoda](http://purl.obolibrary.org/obo/NCBITaxon_6656) + + + +### gingival groove `http://purl.obolibrary.org/obo/UBERON_0008805` +#### Removed +- [gingival groove](http://purl.obolibrary.org/obo/UBERON_0008805) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sulcus gingivalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [gingival groove](http://purl.obolibrary.org/obo/UBERON_0008805) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "sulcus gingivalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Gingival_sulcus" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [gingival groove](http://purl.obolibrary.org/obo/UBERON_0008805) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sulcus gingivalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [gingival groove](http://purl.obolibrary.org/obo/UBERON_0008805) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "sulcus gingivalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Gingival_sulcus" + + +### gland `http://purl.obolibrary.org/obo/UBERON_0002530` +#### Removed +- [gland](http://purl.obolibrary.org/obo/UBERON_0002530) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "glandula" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0000522" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Gland" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [gland](http://purl.obolibrary.org/obo/UBERON_0002530) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00100317" + +#### Added +- [gland](http://purl.obolibrary.org/obo/UBERON_0002530) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00100317" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + +- [gland](http://purl.obolibrary.org/obo/UBERON_0002530) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "glandula" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0000522" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Gland" + + +### gland of nasal mucosa `http://purl.obolibrary.org/obo/UBERON_0012278` +#### Removed +- [gland of nasal mucosa](http://purl.obolibrary.org/obo/UBERON_0012278) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "glandula nasalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [gland of nasal mucosa](http://purl.obolibrary.org/obo/UBERON_0012278) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "glandulae nasales" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [gland of nasal mucosa](http://purl.obolibrary.org/obo/UBERON_0012278) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "glandulae nasales" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [gland of nasal mucosa](http://purl.obolibrary.org/obo/UBERON_0012278) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "glandula nasalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### glandular cell of esophagus `http://purl.obolibrary.org/obo/CL_0002657` + +#### Added +- [glandular cell of esophagus](http://purl.obolibrary.org/obo/CL_0002657) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### glandular epithelial cell `http://purl.obolibrary.org/obo/CL_0000150` + +#### Added +- [glandular epithelial cell](http://purl.obolibrary.org/obo/CL_0000150) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### glenohumeral joint `http://purl.obolibrary.org/obo/UBERON_0001470` +#### Removed +- [glenohumeral joint](http://purl.obolibrary.org/obo/UBERON_0001470) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "articulatio humeri" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:25912" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [glenohumeral joint](http://purl.obolibrary.org/obo/UBERON_0001470) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "articulatio humeri" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:25912" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### glenoid fossa `http://purl.obolibrary.org/obo/UBERON_0006657` +#### Removed +- [glenoid fossa](http://purl.obolibrary.org/obo/UBERON_0006657) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cavitas glenoidalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Glenoid_cavity" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [glenoid fossa](http://purl.obolibrary.org/obo/UBERON_0006657) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cavitas glenoidalis scapulae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:23275" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [glenoid fossa](http://purl.obolibrary.org/obo/UBERON_0006657) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cavitas glenoidalis scapulae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:23275" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [glenoid fossa](http://purl.obolibrary.org/obo/UBERON_0006657) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D061165" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [LexicalMatching](https://w3id.org/semapv/vocab/LexicalMatching) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + +- [glenoid fossa](http://purl.obolibrary.org/obo/UBERON_0006657) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cavitas glenoidalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Glenoid_cavity" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### glial blood brain barrier `http://purl.obolibrary.org/obo/UBERON_0000202` + +#### Added +- [glial blood brain barrier](http://purl.obolibrary.org/obo/UBERON_0000202) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007091" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### glial cell `http://purl.obolibrary.org/obo/CL_0000125` + +#### Added +- [glial cell](http://purl.obolibrary.org/obo/CL_0000125) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### glioblast `http://purl.obolibrary.org/obo/CL_0000030` + +#### Added +- [glioblast](http://purl.obolibrary.org/obo/CL_0000030) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### glomerular basement membrane `http://purl.obolibrary.org/obo/UBERON_0005777` +#### Removed +- [glomerular basement membrane](http://purl.obolibrary.org/obo/UBERON_0005777) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D050533" + +#### Added +- [glomerular basement membrane](http://purl.obolibrary.org/obo/UBERON_0005777) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D050533" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [author_id](https://w3id.org/sssom/author_id) [0000-0001-9439-5346](https://orcid.org/0000-0001-9439-5346) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### glomerular capillary endothelial cell `http://purl.obolibrary.org/obo/CL_1001005` + +#### Added +- [glomerular capillary endothelial cell](http://purl.obolibrary.org/obo/CL_1001005) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### glomerular capsule `http://purl.obolibrary.org/obo/UBERON_0001230` +#### Removed +- [glomerular capsule](http://purl.obolibrary.org/obo/UBERON_0001230) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "capsula glomeruli" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [glomerular capsule](http://purl.obolibrary.org/obo/UBERON_0001230) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "capsula glomerularis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [glomerular capsule](http://purl.obolibrary.org/obo/UBERON_0001230) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "capsula glomerularis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [glomerular capsule](http://purl.obolibrary.org/obo/UBERON_0001230) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "capsula glomeruli" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### glomerular endothelial cell `http://purl.obolibrary.org/obo/CL_0002188` + +#### Added +- [glomerular endothelial cell](http://purl.obolibrary.org/obo/CL_0002188) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### glossopharyngeal nerve `http://purl.obolibrary.org/obo/UBERON_0001649` +#### Removed +- [glossopharyngeal nerve](http://purl.obolibrary.org/obo/UBERON_0001649) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nervus glossopharyngeus [ix]" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:50870" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [glossopharyngeal nerve](http://purl.obolibrary.org/obo/UBERON_0001649) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nervus glossopharyngeus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Glossopharyngeal_nerve" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [glossopharyngeal nerve](http://purl.obolibrary.org/obo/UBERON_0001649) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nervus glossopharyngeus [ix]" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:50870" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [glossopharyngeal nerve](http://purl.obolibrary.org/obo/UBERON_0001649) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nervus glossopharyngeus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Glossopharyngeal_nerve" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### glutamatergic neuron `http://purl.obolibrary.org/obo/CL_0000679` + +#### Added +- [glutamatergic neuron](http://purl.obolibrary.org/obo/CL_0000679) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### glycinergic amacrine cell `http://purl.obolibrary.org/obo/CL_4030028` + +#### Added +- [glycinergic amacrine cell](http://purl.obolibrary.org/obo/CL_4030028) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### goblet cell `http://purl.obolibrary.org/obo/CL_0000160` + +#### Added +- [goblet cell](http://purl.obolibrary.org/obo/CL_0000160) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### gonad `http://purl.obolibrary.org/obo/UBERON_0000991` +#### Removed +- [gonad](http://purl.obolibrary.org/obo/UBERON_0000991) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00004858" + +#### Added +- [gonad](http://purl.obolibrary.org/obo/UBERON_0000991) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00004858" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### gonadal ridge `http://purl.obolibrary.org/obo/UBERON_0005294` +#### Removed +- [gonadal ridge](http://purl.obolibrary.org/obo/UBERON_0005294) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "crista gonadalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Gonadal_ridge" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [gonadal ridge](http://purl.obolibrary.org/obo/UBERON_0005294) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "crista gonadalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Gonadal_ridge" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### goslim_prokaryote `http://purl.obolibrary.org/obo/go#goslim_prokaryote` + +#### Added +- AnnotationProperty: [goslim_prokaryote](http://purl.obolibrary.org/obo/go#goslim_prokaryote) + +- [goslim_prokaryote](http://purl.obolibrary.org/obo/go#goslim_prokaryote) SubPropertyOf: [subset_property](http://www.geneontology.org/formats/oboInOwl#SubsetProperty) + + +### granular cell of epidermis `http://purl.obolibrary.org/obo/CL_0002189` + +#### Added +- [granular cell of epidermis](http://purl.obolibrary.org/obo/CL_0002189) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### granular layer of cerebellar cortex `http://purl.obolibrary.org/obo/UBERON_0002956` +#### Removed +- [granular layer of cerebellar cortex](http://purl.obolibrary.org/obo/UBERON_0002956) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "stratum granulosum corticis cerebelli" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:83140" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [granular layer of cerebellar cortex](http://purl.obolibrary.org/obo/UBERON_0002956) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "stratum granulosum corticis cerebelli" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:83140" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### granule cell `http://purl.obolibrary.org/obo/CL_0000120` + +#### Added +- [granule cell](http://purl.obolibrary.org/obo/CL_0000120) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### granulocyte `http://purl.obolibrary.org/obo/CL_0000094` + +#### Added +- [granulocyte](http://purl.obolibrary.org/obo/CL_0000094) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### granulocyte monocyte progenitor cell `http://purl.obolibrary.org/obo/CL_0000557` + +#### Added +- [granulocyte monocyte progenitor cell](http://purl.obolibrary.org/obo/CL_0000557) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### granulocytopoietic cell `http://purl.obolibrary.org/obo/CL_0002191` + +#### Added +- [granulocytopoietic cell](http://purl.obolibrary.org/obo/CL_0002191) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### granulosa cell `http://purl.obolibrary.org/obo/CL_0000501` + +#### Added +- [granulosa cell](http://purl.obolibrary.org/obo/CL_0000501) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### gravid organism `http://purl.obolibrary.org/obo/UBERON_0009097` + +#### Added +- [gravid organism](http://purl.obolibrary.org/obo/UBERON_0009097) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IDOMAL:0000443" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [LexicalMatching](https://w3id.org/semapv/vocab/LexicalMatching) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### gray matter `http://purl.obolibrary.org/obo/UBERON_0002020` +#### Removed +- [gray matter](http://purl.obolibrary.org/obo/UBERON_0002020) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D066128" + +- [gray matter](http://purl.obolibrary.org/obo/UBERON_0002020) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "substantia grisea" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:67242" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [gray matter](http://purl.obolibrary.org/obo/UBERON_0002020) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "grisea" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [gray matter](http://purl.obolibrary.org/obo/UBERON_0002020) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D066128" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [author_id](https://w3id.org/sssom/author_id) [0000-0001-9439-5346](https://orcid.org/0000-0001-9439-5346) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + +- [gray matter](http://purl.obolibrary.org/obo/UBERON_0002020) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "substantia grisea" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:67242" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [gray matter](http://purl.obolibrary.org/obo/UBERON_0002020) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "grisea" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### gray matter of spinal cord `http://purl.obolibrary.org/obo/UBERON_0002315` +#### Removed +- [gray matter of spinal cord](http://purl.obolibrary.org/obo/UBERON_0002315) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "substantia grisea medullae spinalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:256580" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [gray matter of spinal cord](http://purl.obolibrary.org/obo/UBERON_0002315) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "substantia grisea medullae spinalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:256580" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### great saphenous vein `http://purl.obolibrary.org/obo/UBERON_0001363` +#### Removed +- [great saphenous vein](http://purl.obolibrary.org/obo/UBERON_0001363) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vena saphena magna" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Great_saphenous_vein" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [great saphenous vein](http://purl.obolibrary.org/obo/UBERON_0001363) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vena saphena magna" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Great_saphenous_vein" + + +### group 2 innate lymphoid cell `http://purl.obolibrary.org/obo/CL_0001069` + +#### Added +- [group 2 innate lymphoid cell](http://purl.obolibrary.org/obo/CL_0001069) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### group 2 innate lymphoid cell, human `http://purl.obolibrary.org/obo/CL_0001081` + +#### Added +- [group 2 innate lymphoid cell, human](http://purl.obolibrary.org/obo/CL_0001081) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### group 3 innate lymphoid cell `http://purl.obolibrary.org/obo/CL_0001071` + +#### Added +- [group 3 innate lymphoid cell](http://purl.obolibrary.org/obo/CL_0001071) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### group 3 innate lymphoid cell, human `http://purl.obolibrary.org/obo/CL_0001078` + +#### Added +- [group 3 innate lymphoid cell, human](http://purl.obolibrary.org/obo/CL_0001078) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### gustatory organ `http://purl.obolibrary.org/obo/UBERON_0003212` +#### Removed +- [gustatory organ](http://purl.obolibrary.org/obo/UBERON_0003212) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005159" + +#### Added +- [gustatory organ](http://purl.obolibrary.org/obo/UBERON_0003212) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005159" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### gut absorptive cell `http://purl.obolibrary.org/obo/CL_0000677` + +#### Added +- [gut absorptive cell](http://purl.obolibrary.org/obo/CL_0000677) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### gut endothelial cell `http://purl.obolibrary.org/obo/CL_0000131` + +#### Added +- [gut endothelial cell](http://purl.obolibrary.org/obo/CL_0000131) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### hair follicle `http://purl.obolibrary.org/obo/UBERON_0002073` +#### Removed +- [hair follicle](http://purl.obolibrary.org/obo/UBERON_0002073) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "folliculus pili" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Hair_follicle" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [hair follicle](http://purl.obolibrary.org/obo/UBERON_0002073) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "folliculus pili" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Hair_follicle" + + +### hair follicular keratinocyte `http://purl.obolibrary.org/obo/CL_2000092` + +#### Added +- [hair follicular keratinocyte](http://purl.obolibrary.org/obo/CL_2000092) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### hair root sheath `http://purl.obolibrary.org/obo/UBERON_0005933` +#### Removed +- [hair root sheath](http://purl.obolibrary.org/obo/UBERON_0005933) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "https://github.com/obophenotype/mouse-anatomy-ontology/issues/56" + +#### Added +- [hair root sheath](http://purl.obolibrary.org/obo/UBERON_0005933) [see also](http://www.w3.org/2000/01/rdf-schema#seeAlso) "https://github.com/obophenotype/mouse-anatomy-ontology/issues/56"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + + +### head sensillum `http://purl.obolibrary.org/obo/UBERON_0000963` +#### Removed +- [head sensillum](http://purl.obolibrary.org/obo/UBERON_0000963) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00004114" + +#### Added +- [head sensillum](http://purl.obolibrary.org/obo/UBERON_0000963) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00004114" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### heart left ventricle `http://purl.obolibrary.org/obo/UBERON_0002084` +#### Removed +- [heart left ventricle](http://purl.obolibrary.org/obo/UBERON_0002084) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ventriculus sinister cordis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Left_ventricle" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [heart left ventricle](http://purl.obolibrary.org/obo/UBERON_0002084) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ventriculus sinister cordis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Left_ventricle" + + +### heart right ventricle `http://purl.obolibrary.org/obo/UBERON_0002080` +#### Removed +- [heart right ventricle](http://purl.obolibrary.org/obo/UBERON_0002080) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ventriculus dexter" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Right_ventricle" + +#### Added +- [heart right ventricle](http://purl.obolibrary.org/obo/UBERON_0002080) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ventriculus dexter" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Right_ventricle" + + +### helper T cell `http://purl.obolibrary.org/obo/CL_0000912` + +#### Added +- [helper T cell](http://purl.obolibrary.org/obo/CL_0000912) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### hematopoietic cell `http://purl.obolibrary.org/obo/CL_0000988` + +#### Added +- [hematopoietic cell](http://purl.obolibrary.org/obo/CL_0000988) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### hematopoietic multipotent progenitor cell `http://purl.obolibrary.org/obo/CL_0000837` + +#### Added +- [hematopoietic multipotent progenitor cell](http://purl.obolibrary.org/obo/CL_0000837) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### hematopoietic precursor cell `http://purl.obolibrary.org/obo/CL_0008001` + +#### Added +- [hematopoietic precursor cell](http://purl.obolibrary.org/obo/CL_0008001) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### hematopoietic stem cell `http://purl.obolibrary.org/obo/CL_0000037` + +#### Added +- [hematopoietic stem cell](http://purl.obolibrary.org/obo/CL_0000037) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### hepatic artery `http://purl.obolibrary.org/obo/UBERON_0001193` +#### Removed +- [hepatic artery](http://purl.obolibrary.org/obo/UBERON_0001193) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "arteria hepatica propria" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [hepatic artery](http://purl.obolibrary.org/obo/UBERON_0001193) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "arteria hepatica propria" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### hepatic diverticulum `http://purl.obolibrary.org/obo/UBERON_0008835` +#### Removed +- [hepatic diverticulum](http://purl.obolibrary.org/obo/UBERON_0008835) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "diverticulum hepaticum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Hepatic_diverticulum" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [hepatic diverticulum](http://purl.obolibrary.org/obo/UBERON_0008835) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "diverticulum hepaticum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Hepatic_diverticulum" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### hepatic portal vein `http://purl.obolibrary.org/obo/UBERON_0001639` +#### Removed +- [hepatic portal vein](http://purl.obolibrary.org/obo/UBERON_0001639) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vena portae hepatis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Hepatic_portal_vein" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [hepatic portal vein](http://purl.obolibrary.org/obo/UBERON_0001639) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vena portae hepatis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Hepatic_portal_vein" + + +### hepatic sinusoid `http://purl.obolibrary.org/obo/UBERON_0001281` +#### Removed +- [hepatic sinusoid](http://purl.obolibrary.org/obo/UBERON_0001281) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "vas sinusoideum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Hepatic_sinusoid" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [hepatic sinusoid](http://purl.obolibrary.org/obo/UBERON_0001281) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "vas sinusoideum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Hepatic_sinusoid" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### hepatic stellate cell `http://purl.obolibrary.org/obo/CL_0000632` + +#### Added +- [hepatic stellate cell](http://purl.obolibrary.org/obo/CL_0000632) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### hepatic vein `http://purl.obolibrary.org/obo/UBERON_0001143` +#### Removed +- [hepatic vein](http://purl.obolibrary.org/obo/UBERON_0001143) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "vena hepatica" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [hepatic vein](http://purl.obolibrary.org/obo/UBERON_0001143) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "venae hepaticae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Hepatic_vein" + +#### Added +- [hepatic vein](http://purl.obolibrary.org/obo/UBERON_0001143) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "venae hepaticae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Hepatic_vein" + +- [hepatic vein](http://purl.obolibrary.org/obo/UBERON_0001143) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "vena hepatica" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### hepatoblast `http://purl.obolibrary.org/obo/CL_0005026` + +#### Added +- [hepatoblast](http://purl.obolibrary.org/obo/CL_0005026) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### hepatocyte `http://purl.obolibrary.org/obo/CL_0000182` + +#### Added +- [hepatocyte](http://purl.obolibrary.org/obo/CL_0000182) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### hepatopancreatic ampulla `http://purl.obolibrary.org/obo/UBERON_0004913` +#### Removed +- [hepatopancreatic ampulla](http://purl.obolibrary.org/obo/UBERON_0004913) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ampulla Vaterii" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Ampulla_of_Vater" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [hepatopancreatic ampulla](http://purl.obolibrary.org/obo/UBERON_0004913) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ampulla hepatopancreatica" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Ampulla_of_Vater" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [hepatopancreatic ampulla](http://purl.obolibrary.org/obo/UBERON_0004913) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ampulla biliaropancreatica" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:15076" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [hepatopancreatic ampulla](http://purl.obolibrary.org/obo/UBERON_0004913) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ampulla hepatopancreatica" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Ampulla_of_Vater" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [hepatopancreatic ampulla](http://purl.obolibrary.org/obo/UBERON_0004913) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ampulla Vaterii" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Ampulla_of_Vater" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [hepatopancreatic ampulla](http://purl.obolibrary.org/obo/UBERON_0004913) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ampulla biliaropancreatica" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:15076" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### high nuclear/cytoplasmic ratio `http://purl.obolibrary.org/obo/PATO_0040072` + +#### Added +- [high nuclear/cytoplasmic ratio](http://purl.obolibrary.org/obo/PATO_0040072) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "high N:C ratio" + +- [high nuclear/cytoplasmic ratio](http://purl.obolibrary.org/obo/PATO_0040072) [created by](http://www.geneontology.org/formats/oboInOwl#created_by) "http://orcid.org/0000-0001-5208-3432" + +- [high nuclear/cytoplasmic ratio](http://purl.obolibrary.org/obo/PATO_0040072) [label](http://www.w3.org/2000/01/rdf-schema#label) "high nuclear/cytoplasmic ratio" + +- [high nuclear/cytoplasmic ratio](http://purl.obolibrary.org/obo/PATO_0040072) [id](http://www.geneontology.org/formats/oboInOwl#id) "PATO:0040072" + +- [high nuclear/cytoplasmic ratio](http://purl.obolibrary.org/obo/PATO_0040072) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "A high nuclear/cytolasmic ratio is 70% or higher." + +- [high nuclear/cytoplasmic ratio](http://purl.obolibrary.org/obo/PATO_0040072) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A quality inhering in a cell by virtue of the cell having a high nuclear/cytoplasmic ratio." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "http://lymerick.net/blood-cells.pdf" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:NC_ratio&oldid=931936284" + +- [high nuclear/cytoplasmic ratio](http://purl.obolibrary.org/obo/PATO_0040072) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "quality" + +- Class: [high nuclear/cytoplasmic ratio](http://purl.obolibrary.org/obo/PATO_0040072) + +- [high nuclear/cytoplasmic ratio](http://purl.obolibrary.org/obo/PATO_0040072) SubClassOf [cellular quality](http://purl.obolibrary.org/obo/PATO_0001396) + + +### hindgut `http://purl.obolibrary.org/obo/UBERON_0001046` +#### Removed +- [hindgut](http://purl.obolibrary.org/obo/UBERON_0001046) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "metenteron" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Hindgut" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [hindgut](http://purl.obolibrary.org/obo/UBERON_0001046) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005384" + +#### Added +- [hindgut](http://purl.obolibrary.org/obo/UBERON_0001046) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "metenteron" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Hindgut" + +- [hindgut](http://purl.obolibrary.org/obo/UBERON_0001046) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005384" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### hindlimb `http://purl.obolibrary.org/obo/UBERON_0002103` +#### Removed +- [hindlimb](http://purl.obolibrary.org/obo/UBERON_0002103) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "membrum inferius" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:7184" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [hindlimb](http://purl.obolibrary.org/obo/UBERON_0002103) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "membrum inferius" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Lower_limb" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [hindlimb](http://purl.obolibrary.org/obo/UBERON_0002103) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "membrum inferius" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Lower_limb" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [hindlimb](http://purl.obolibrary.org/obo/UBERON_0002103) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "membrum inferius" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:7184" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### hindlimb muscle `http://purl.obolibrary.org/obo/UBERON_0003663` + +#### Added +- [hindlimb muscle](http://purl.obolibrary.org/obo/UBERON_0003663) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [human_reference_atlas](http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas) + +- [hindlimb muscle](http://purl.obolibrary.org/obo/UBERON_0003663) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606) + + +### hindlimb skeleton `http://purl.obolibrary.org/obo/UBERON_0001441` +#### Removed +- [hindlimb skeleton](http://purl.obolibrary.org/obo/UBERON_0001441) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ossa membri inferioris" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:24140" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [hindlimb skeleton](http://purl.obolibrary.org/obo/UBERON_0001441) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ossa membri inferioris" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:24140" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### hindlimb stylopod `http://purl.obolibrary.org/obo/UBERON_0000376` +#### Removed +- [hindlimb stylopod](http://purl.obolibrary.org/obo/UBERON_0000376) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "femur" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Thigh" + +#### Added +- [hindlimb stylopod](http://purl.obolibrary.org/obo/UBERON_0000376) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "femur" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Thigh" + + +### hindlimb zeugopod `http://purl.obolibrary.org/obo/UBERON_0003823` + +#### Added +- [hindlimb zeugopod](http://purl.obolibrary.org/obo/UBERON_0003823) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "VO:0010971" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + - [author_id](https://w3id.org/sssom/author_id) [0000-0003-4423-4370](https://orcid.org/0000-0003-4423-4370) + + +### hindlimb zeugopod muscle `http://purl.obolibrary.org/obo/UBERON_0004256` + +#### Added +- [hindlimb zeugopod muscle](http://purl.obolibrary.org/obo/UBERON_0004256) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606) + +- [hindlimb zeugopod muscle](http://purl.obolibrary.org/obo/UBERON_0004256) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [human_reference_atlas](http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas) + + +### hindlimb zeugopod skeleton `http://purl.obolibrary.org/obo/UBERON_0010720` +#### Removed +- [hindlimb zeugopod skeleton](http://purl.obolibrary.org/obo/UBERON_0010720) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "skeleton cruris" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NominaAnatomicaVeterinaria:2005" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [hindlimb zeugopod skeleton](http://purl.obolibrary.org/obo/UBERON_0010720) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "skeleton cruris" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NominaAnatomicaVeterinaria:2005" + + +### hip `http://purl.obolibrary.org/obo/UBERON_0001464` +#### Removed +- [hip](http://purl.obolibrary.org/obo/UBERON_0001464) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "coxa" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Hip" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [hip](http://purl.obolibrary.org/obo/UBERON_0001464) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "coxa" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Hip" + + +### hippocampal formation `http://purl.obolibrary.org/obo/UBERON_0002421` +#### Removed +- [hippocampal formation](http://purl.obolibrary.org/obo/UBERON_0002421) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "formatio hippocampi" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:177" + +#### Added +- [hippocampal formation](http://purl.obolibrary.org/obo/UBERON_0002421) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "formatio hippocampi" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:177" + + +### hippocampal neuron `http://purl.obolibrary.org/obo/CL_0002608` + +#### Added +- [hippocampal neuron](http://purl.obolibrary.org/obo/CL_0002608) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### hippocampus alveus `http://purl.obolibrary.org/obo/UBERON_0007639` +#### Removed +- [hippocampus alveus](http://purl.obolibrary.org/obo/UBERON_0007639) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "alveus hippocampi" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:186" + +#### Added +- [hippocampus alveus](http://purl.obolibrary.org/obo/UBERON_0007639) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "alveus hippocampi" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:186" + + +### hippocampus fimbria `http://purl.obolibrary.org/obo/UBERON_0002310` +#### Removed +- [hippocampus fimbria](http://purl.obolibrary.org/obo/UBERON_0002310) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "fimbria fornicis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:187" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [hippocampus fimbria](http://purl.obolibrary.org/obo/UBERON_0002310) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "fimbria hippocampi" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Fimbria_of_hippocampus" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:187" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [hippocampus fimbria](http://purl.obolibrary.org/obo/UBERON_0002310) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "fimbria fornicis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:187" + +- [hippocampus fimbria](http://purl.obolibrary.org/obo/UBERON_0002310) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "fimbria hippocampi" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Fimbria_of_hippocampus" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:187" + + +### hippocampus pyramidal layer `http://purl.obolibrary.org/obo/UBERON_0002313` +#### Removed +- [hippocampus pyramidal layer](http://purl.obolibrary.org/obo/UBERON_0002313) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "gyrus occipitalis tertius" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:156" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [hippocampus pyramidal layer](http://purl.obolibrary.org/obo/UBERON_0002313) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "gyrus occipitalis inferior" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:156" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [hippocampus pyramidal layer](http://purl.obolibrary.org/obo/UBERON_0002313) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "gyrus occipitalis inferior" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:156" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [hippocampus pyramidal layer](http://purl.obolibrary.org/obo/UBERON_0002313) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "gyrus occipitalis tertius" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:156" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### hippocampus stratum lucidum `http://purl.obolibrary.org/obo/UBERON_0007637` +#### Removed +- [hippocampus stratum lucidum](http://purl.obolibrary.org/obo/UBERON_0007637) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "stratum lucidum hippocampi" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Stratum_lucidum_of_hippocampus" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [hippocampus stratum lucidum](http://purl.obolibrary.org/obo/UBERON_0007637) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "stratum lucidum hippocampi" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Stratum_lucidum_of_hippocampus" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### hippocampus stratum oriens `http://purl.obolibrary.org/obo/UBERON_0005371` +#### Removed +- [hippocampus stratum oriens](http://purl.obolibrary.org/obo/UBERON_0005371) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "gyrus cuneus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:157" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [hippocampus stratum oriens](http://purl.obolibrary.org/obo/UBERON_0005371) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "stratum oriens hippocampi" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:83893" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [hippocampus stratum oriens](http://purl.obolibrary.org/obo/UBERON_0005371) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "stratum oriens hippocampi" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:83893" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [hippocampus stratum oriens](http://purl.obolibrary.org/obo/UBERON_0005371) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "gyrus cuneus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:157" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### hippocampus stratum radiatum `http://purl.obolibrary.org/obo/UBERON_0005372` +#### Removed +- [hippocampus stratum radiatum](http://purl.obolibrary.org/obo/UBERON_0005372) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "stratum radiatum hippocampi" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:83894" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [hippocampus stratum radiatum](http://purl.obolibrary.org/obo/UBERON_0005372) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "stratum radiatum hippocampi" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:83894" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### humerus diaphysis `http://purl.obolibrary.org/obo/UBERON_0004652` +#### Removed +- [humerus diaphysis](http://purl.obolibrary.org/obo/UBERON_0004652) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "corpus humeri" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:13305" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [humerus diaphysis](http://purl.obolibrary.org/obo/UBERON_0004652) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "corpus humeri" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:13305" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### hydrolase activity `http://purl.obolibrary.org/obo/GO_0016787` +#### Removed +- [hydrolase activity](http://purl.obolibrary.org/obo/GO_0016787) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [prokaryote_subset](http://purl.obolibrary.org/obo/go#prokaryote_subset) + +#### Added +- [hydrolase activity](http://purl.obolibrary.org/obo/GO_0016787) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_prokaryote](http://purl.obolibrary.org/obo/go#goslim_prokaryote) + + +### hydroxyapatite binding `http://purl.obolibrary.org/obo/GO_0046848` +#### Removed +- [hydroxyapatite binding](http://purl.obolibrary.org/obo/GO_0046848) SubClassOf [binding](http://purl.obolibrary.org/obo/GO_0005488) + +#### Added +- [hydroxyapatite binding](http://purl.obolibrary.org/obo/GO_0046848) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) "https://github.com/geneontology/go-ontology/issues/21211"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + +- [hydroxyapatite binding](http://purl.obolibrary.org/obo/GO_0046848) SubClassOf [small molecule binding](http://purl.obolibrary.org/obo/GO_0036094) + + +### hyoid apparatus `http://purl.obolibrary.org/obo/UBERON_0010272` +#### Removed +- [hyoid apparatus](http://purl.obolibrary.org/obo/UBERON_0010272) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "apparatus hyobranchialis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [hyoid apparatus](http://purl.obolibrary.org/obo/UBERON_0010272) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "apparatus hyobranchialis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### hyoid bone `http://purl.obolibrary.org/obo/UBERON_0001685` +#### Removed +- [hyoid bone](http://purl.obolibrary.org/obo/UBERON_0001685) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "os hyoideum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Hyoid_bone" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [hyoid bone](http://purl.obolibrary.org/obo/UBERON_0001685) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "os hyoideum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Hyoid_bone" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### hypendymal cell `http://purl.obolibrary.org/obo/CL_4023181` + +#### Added +- [hypendymal cell](http://purl.obolibrary.org/obo/CL_4023181) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### hypodermis `http://purl.obolibrary.org/obo/UBERON_0002072` +#### Removed +- [hypodermis](http://purl.obolibrary.org/obo/UBERON_0002072) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tela subcutanea" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Hypodermis" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [hypodermis](http://purl.obolibrary.org/obo/UBERON_0002072) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D040521" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [LexicalMatching](https://w3id.org/semapv/vocab/LexicalMatching) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + +- [hypodermis](http://purl.obolibrary.org/obo/UBERON_0002072) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tela subcutanea" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Hypodermis" + + +### hypoglossal canal `http://purl.obolibrary.org/obo/UBERON_0006682` +#### Removed +- [hypoglossal canal](http://purl.obolibrary.org/obo/UBERON_0006682) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "canalis nervi hypoglossi" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Hypoglossal_canal" + +#### Added +- [hypoglossal canal](http://purl.obolibrary.org/obo/UBERON_0006682) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "canalis nervi hypoglossi" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Hypoglossal_canal" + + +### hypoglossal nerve `http://purl.obolibrary.org/obo/UBERON_0001650` +#### Removed +- [hypoglossal nerve](http://purl.obolibrary.org/obo/UBERON_0001650) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nervus hypoglossus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Hypoglossal_nerve" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [hypoglossal nerve](http://purl.obolibrary.org/obo/UBERON_0001650) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nervus hypoglossus [xii]" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:50871" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [hypoglossal nerve](http://purl.obolibrary.org/obo/UBERON_0001650) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nervi hypoglossalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:704" + +#### Added +- [hypoglossal nerve](http://purl.obolibrary.org/obo/UBERON_0001650) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nervus hypoglossus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Hypoglossal_nerve" + +- [hypoglossal nerve](http://purl.obolibrary.org/obo/UBERON_0001650) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nervi hypoglossalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:704" + +- [hypoglossal nerve](http://purl.obolibrary.org/obo/UBERON_0001650) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nervus hypoglossus [xii]" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:50871" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### hypoglossal nerve root `http://purl.obolibrary.org/obo/UBERON_0004675` +#### Removed +- [hypoglossal nerve root](http://purl.obolibrary.org/obo/UBERON_0004675) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "fibrae nervi hypoglossi" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:72632" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [hypoglossal nerve root](http://purl.obolibrary.org/obo/UBERON_0004675) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "fibrae nervi hypoglossi" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:72632" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### hypoglossal nucleus `http://purl.obolibrary.org/obo/UBERON_0002871` +#### Removed +- [hypoglossal nucleus](http://purl.obolibrary.org/obo/UBERON_0002871) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nucleus nervi hypoglossi" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:54505" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [hypoglossal nucleus](http://purl.obolibrary.org/obo/UBERON_0002871) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus hypoglossalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:757" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [hypoglossal nucleus](http://purl.obolibrary.org/obo/UBERON_0002871) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus nervi hypoglossi" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Hypoglossal_nucleus" + +#### Added +- [hypoglossal nucleus](http://purl.obolibrary.org/obo/UBERON_0002871) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nucleus nervi hypoglossi" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:54505" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [hypoglossal nucleus](http://purl.obolibrary.org/obo/UBERON_0002871) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus nervi hypoglossi" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Hypoglossal_nucleus" + +- [hypoglossal nucleus](http://purl.obolibrary.org/obo/UBERON_0002871) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus hypoglossalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:757" + + +### hypothalamus `http://purl.obolibrary.org/obo/UBERON_0001898` +#### Removed +- [hypothalamus](http://purl.obolibrary.org/obo/UBERON_0001898) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "hypothalamus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Hypothalamus" + +#### Added +- [hypothalamus](http://purl.obolibrary.org/obo/UBERON_0001898) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "hypothalamus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Hypothalamus" + + +### ileal goblet cell `http://purl.obolibrary.org/obo/CL_1000326` + +#### Added +- [ileal goblet cell](http://purl.obolibrary.org/obo/CL_1000326) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### ileocolic artery `http://purl.obolibrary.org/obo/UBERON_0001197` +#### Removed +- [ileocolic artery](http://purl.obolibrary.org/obo/UBERON_0001197) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria ileocolica" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Ileocolic_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [ileocolic artery](http://purl.obolibrary.org/obo/UBERON_0001197) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria ileocolica" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Ileocolic_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### ileocolic vein `http://purl.obolibrary.org/obo/UBERON_0001219` +#### Removed +- [ileocolic vein](http://purl.obolibrary.org/obo/UBERON_0001219) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vena ileocolica" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Ileocolic_vein" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [ileocolic vein](http://purl.obolibrary.org/obo/UBERON_0001219) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vena ileocolica" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Ileocolic_vein" + + +### ileum lamina propria `http://purl.obolibrary.org/obo/UBERON_8600035` + +#### Added +- [ileum lamina propria](http://purl.obolibrary.org/obo/UBERON_8600035) [label](http://www.w3.org/2000/01/rdf-schema#label) "ileum lamina propria" + +- [ileum lamina propria](http://purl.obolibrary.org/obo/UBERON_8600035) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "uberon" + +- [ileum lamina propria](http://purl.obolibrary.org/obo/UBERON_8600035) [id](http://www.geneontology.org/formats/oboInOwl#id) "UBERON:8600035" + +- [ileum lamina propria](http://purl.obolibrary.org/obo/UBERON_8600035) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lamina propria of ileum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:36067905" + +- [ileum lamina propria](http://purl.obolibrary.org/obo/UBERON_8600035) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A lamina propria that is part of an ileum." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:29316348" + +- [ileum lamina propria](http://purl.obolibrary.org/obo/UBERON_8600035) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ileal lamina propria" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:37467267" + +- [ileum lamina propria](http://purl.obolibrary.org/obo/UBERON_8600035) [contributor](http://purl.org/dc/terms/contributor) [0000-0001-8134-3037](https://orcid.org/0000-0001-8134-3037) + +- [ileum lamina propria](http://purl.obolibrary.org/obo/UBERON_8600035) [contributor](http://purl.org/dc/terms/contributor) [0000-0001-6677-8489](https://orcid.org/0000-0001-6677-8489) + +- [ileum lamina propria](http://purl.obolibrary.org/obo/UBERON_8600035) [date](http://purl.org/dc/terms/date) "2024-01-09T16:48:17Z"^^[dateTime](http://www.w3.org/2001/XMLSchema#dateTime) + +- Class: [ileum lamina propria](http://purl.obolibrary.org/obo/UBERON_8600035) + +- [ileum lamina propria](http://purl.obolibrary.org/obo/UBERON_8600035) EquivalentTo [lamina propria](http://purl.obolibrary.org/obo/UBERON_0000030) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [ileum](http://purl.obolibrary.org/obo/UBERON_0002116)) + +- [ileum lamina propria](http://purl.obolibrary.org/obo/UBERON_8600035) SubClassOf [lamina propria of small intestine](http://purl.obolibrary.org/obo/UBERON_0001238) + +- [ileum lamina propria](http://purl.obolibrary.org/obo/UBERON_8600035) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [intestinal villus of ileum](http://purl.obolibrary.org/obo/UBERON_0008344) + + +### ilium `http://purl.obolibrary.org/obo/UBERON_0001273` +#### Removed +- [ilium](http://purl.obolibrary.org/obo/UBERON_0001273) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "os ilium" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:16589" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [ilium](http://purl.obolibrary.org/obo/UBERON_0001273) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "os ilium" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:16589" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### imaginal disc `http://purl.obolibrary.org/obo/UBERON_0000939` +#### Removed +- [imaginal disc](http://purl.obolibrary.org/obo/UBERON_0000939) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00001761" + +- [imaginal disc](http://purl.obolibrary.org/obo/UBERON_0000939) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D060227" + +#### Added +- [imaginal disc](http://purl.obolibrary.org/obo/UBERON_0000939) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00001761" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + +- [imaginal disc](http://purl.obolibrary.org/obo/UBERON_0000939) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D060227" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [author_id](https://w3id.org/sssom/author_id) [0000-0001-9439-5346](https://orcid.org/0000-0001-9439-5346) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### immaterial anatomical entity `http://purl.obolibrary.org/obo/UBERON_0000466` +#### Removed +- [immaterial anatomical entity](http://purl.obolibrary.org/obo/UBERON_0000466) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007015" + +#### Added +- [immaterial anatomical entity](http://purl.obolibrary.org/obo/UBERON_0000466) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007015" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### immature B cell `http://purl.obolibrary.org/obo/CL_0000816` + +#### Added +- [immature B cell](http://purl.obolibrary.org/obo/CL_0000816) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### immature NK T cell `http://purl.obolibrary.org/obo/CL_0000914` + +#### Added +- [immature NK T cell](http://purl.obolibrary.org/obo/CL_0000914) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### immature Schwann cell `http://purl.obolibrary.org/obo/CL_0002377` + +#### Added +- [immature Schwann cell](http://purl.obolibrary.org/obo/CL_0002377) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### immature T cell `http://purl.obolibrary.org/obo/CL_0002420` + +#### Added +- [immature T cell](http://purl.obolibrary.org/obo/CL_0002420) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### immature alpha-beta T cell `http://purl.obolibrary.org/obo/CL_0000790` + +#### Added +- [immature alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000790) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### immature innate lymphoid cell `http://purl.obolibrary.org/obo/CL_0001082` + +#### Added +- [immature innate lymphoid cell](http://purl.obolibrary.org/obo/CL_0001082) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### immature natural killer cell `http://purl.obolibrary.org/obo/CL_0000823` + +#### Added +- [immature natural killer cell](http://purl.obolibrary.org/obo/CL_0000823) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### immature neutrophil `http://purl.obolibrary.org/obo/CL_0000776` + +#### Added +- [immature neutrophil](http://purl.obolibrary.org/obo/CL_0000776) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### import across plasma membrane `http://purl.obolibrary.org/obo/GO_0098739` +#### Removed +- [import across plasma membrane](http://purl.obolibrary.org/obo/GO_0098739) SubClassOf [has target start location](http://purl.obolibrary.org/obo/RO_0002338) some [extracellular region](http://purl.obolibrary.org/obo/GO_0005576) + +#### Added +- [import across plasma membrane](http://purl.obolibrary.org/obo/GO_0098739) SubClassOf [import into cell](http://purl.obolibrary.org/obo/GO_0098657) + + +### inferior angle of scapula `http://purl.obolibrary.org/obo/UBERON_0007175` +#### Removed +- [inferior angle of scapula](http://purl.obolibrary.org/obo/UBERON_0007175) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "angulus inferior scapulae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Inferior_angle_of_scapula" + +#### Added +- [inferior angle of scapula](http://purl.obolibrary.org/obo/UBERON_0007175) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "angulus inferior scapulae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Inferior_angle_of_scapula" + + +### inferior mesenteric artery `http://purl.obolibrary.org/obo/UBERON_0001183` +#### Removed +- [inferior mesenteric artery](http://purl.obolibrary.org/obo/UBERON_0001183) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria mesenterica inferior" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Inferior_mesenteric_artery" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0002302" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [inferior mesenteric artery](http://purl.obolibrary.org/obo/UBERON_0001183) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria mesenterica inferior" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Inferior_mesenteric_artery" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0002302" + + +### inferior mesenteric vein `http://purl.obolibrary.org/obo/UBERON_0001215` +#### Removed +- [inferior mesenteric vein](http://purl.obolibrary.org/obo/UBERON_0001215) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vena mesenterica inferior" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Inferior_mesenteric_vein" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [inferior mesenteric vein](http://purl.obolibrary.org/obo/UBERON_0001215) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vena mesenterica inferior" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Inferior_mesenteric_vein" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### inferior suprarenal artery `http://purl.obolibrary.org/obo/UBERON_0002056` +#### Removed +- [inferior suprarenal artery](http://purl.obolibrary.org/obo/UBERON_0002056) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria suprarenalis inferior" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Inferior_suprarenal_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [inferior suprarenal artery](http://purl.obolibrary.org/obo/UBERON_0002056) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria suprarenalis inferior" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Inferior_suprarenal_artery" + + +### inferior vesical artery `http://purl.obolibrary.org/obo/UBERON_0001311` +#### Removed +- [inferior vesical artery](http://purl.obolibrary.org/obo/UBERON_0001311) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria vesicalis inferior" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Inferior_vesical_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [inferior vesical artery](http://purl.obolibrary.org/obo/UBERON_0001311) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "arteria vesicali inferior" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Inferior_vesical_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [inferior vesical artery](http://purl.obolibrary.org/obo/UBERON_0001311) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "arteria vesicalis inferior" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Inferior_vesical_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [inferior vesical artery](http://purl.obolibrary.org/obo/UBERON_0001311) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "arteria vesicali inferior" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Inferior_vesical_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [inferior vesical artery](http://purl.obolibrary.org/obo/UBERON_0001311) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "arteria vesicalis inferior" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Inferior_vesical_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [inferior vesical artery](http://purl.obolibrary.org/obo/UBERON_0001311) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria vesicalis inferior" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Inferior_vesical_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### inflammatory cell `http://purl.obolibrary.org/obo/CL_0009002` + +#### Added +- [inflammatory cell](http://purl.obolibrary.org/obo/CL_0009002) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### inflammatory macrophage `http://purl.obolibrary.org/obo/CL_0000863` + +#### Added +- [inflammatory macrophage](http://purl.obolibrary.org/obo/CL_0000863) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### inhibitory interneuron `http://purl.obolibrary.org/obo/CL_0000498` + +#### Added +- [inhibitory interneuron](http://purl.obolibrary.org/obo/CL_0000498) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### inhibitory motor neuron `http://purl.obolibrary.org/obo/CL_0008015` + +#### Added +- [inhibitory motor neuron](http://purl.obolibrary.org/obo/CL_0008015) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### innate immune response `http://purl.obolibrary.org/obo/GO_0045087` +#### Removed +- [innate immune response](http://purl.obolibrary.org/obo/GO_0045087) SubClassOf [defense response to other organism](http://purl.obolibrary.org/obo/GO_0098542) + +#### Added +- [innate immune response](http://purl.obolibrary.org/obo/GO_0045087) SubClassOf [defense response to symbiont](http://purl.obolibrary.org/obo/GO_0140546) + + +### innate lymphoid cell `http://purl.obolibrary.org/obo/CL_0001065` + +#### Added +- [innate lymphoid cell](http://purl.obolibrary.org/obo/CL_0001065) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### inner cell mass `http://purl.obolibrary.org/obo/UBERON_0000087` +#### Removed +- [inner cell mass](http://purl.obolibrary.org/obo/UBERON_0000087) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "embryoblastus; massa cellularis interna; pluriblastus senior" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Inner_cell_mass" + +#### Added +- [inner cell mass](http://purl.obolibrary.org/obo/UBERON_0000087) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "embryoblastus; massa cellularis interna; pluriblastus senior" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Inner_cell_mass" + + +### inner limiting layer of retina `http://purl.obolibrary.org/obo/UBERON_0001794` +#### Removed +- [inner limiting layer of retina](http://purl.obolibrary.org/obo/UBERON_0001794) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "stratum limitans internum retinae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:58689" + +#### Added +- [inner limiting layer of retina](http://purl.obolibrary.org/obo/UBERON_0001794) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "stratum limitans internum retinae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:58689" + + +### inner medulla of kidney `http://purl.obolibrary.org/obo/UBERON_0001294` +#### Removed +- [inner medulla of kidney](http://purl.obolibrary.org/obo/UBERON_0001294) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "zona interna medullae renalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:17734" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [inner medulla of kidney](http://purl.obolibrary.org/obo/UBERON_0001294) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "zona interna (medullaris renalis)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:17734" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [inner medulla of kidney](http://purl.obolibrary.org/obo/UBERON_0001294) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "zona interna medullae renalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:17734" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [inner medulla of kidney](http://purl.obolibrary.org/obo/UBERON_0001294) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "zona interna (medullaris renalis)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:17734" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### inner nuclear layer of retina `http://purl.obolibrary.org/obo/UBERON_0001791` +#### Removed +- [inner nuclear layer of retina](http://purl.obolibrary.org/obo/UBERON_0001791) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "stratum nucleare internum retinae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:58686" + +#### Added +- [inner nuclear layer of retina](http://purl.obolibrary.org/obo/UBERON_0001791) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "stratum nucleare internum retinae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:58686" + + +### inner plexiform layer of retina `http://purl.obolibrary.org/obo/UBERON_0001795` +#### Removed +- [inner plexiform layer of retina](http://purl.obolibrary.org/obo/UBERON_0001795) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "stratum plexiforme internum retinae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Inner_plexiform_layer" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [inner plexiform layer of retina](http://purl.obolibrary.org/obo/UBERON_0001795) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "stratum plexiforme internum retinae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Inner_plexiform_layer" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### innominate bone `http://purl.obolibrary.org/obo/UBERON_0001272` +#### Removed +- [innominate bone](http://purl.obolibrary.org/obo/UBERON_0001272) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "os coxa" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [innominate bone](http://purl.obolibrary.org/obo/UBERON_0001272) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "os innominatum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Hip_bone" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [innominate bone](http://purl.obolibrary.org/obo/UBERON_0001272) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "os coxae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:16585" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [innominate bone](http://purl.obolibrary.org/obo/UBERON_0001272) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "os coxae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:16585" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [innominate bone](http://purl.obolibrary.org/obo/UBERON_0001272) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "os innominatum" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Hip_bone" + +- [innominate bone](http://purl.obolibrary.org/obo/UBERON_0001272) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "os coxa" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### insect adult head `http://purl.obolibrary.org/obo/UBERON_6003007` +#### Removed +- [insect adult head](http://purl.obolibrary.org/obo/UBERON_6003007) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00003007" + +#### Added +- [insect adult head](http://purl.obolibrary.org/obo/UBERON_6003007) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00003007" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### insect adult tagma `http://purl.obolibrary.org/obo/UBERON_6003005` +#### Removed +- [insect adult tagma](http://purl.obolibrary.org/obo/UBERON_6003005) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00003005" + +#### Added +- [insect adult tagma](http://purl.obolibrary.org/obo/UBERON_6003005) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00003005" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### insect embryonic/larval head sense organ `http://purl.obolibrary.org/obo/UBERON_6007280` +#### Removed +- [insect embryonic/larval head sense organ](http://purl.obolibrary.org/obo/UBERON_6007280) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007280" + +#### Added +- [insect embryonic/larval head sense organ](http://purl.obolibrary.org/obo/UBERON_6007280) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007280" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### insect embryonic/larval head sensillum `http://purl.obolibrary.org/obo/UBERON_6007242` +#### Removed +- [insect embryonic/larval head sensillum](http://purl.obolibrary.org/obo/UBERON_6007242) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007242" + +#### Added +- [insect embryonic/larval head sensillum](http://purl.obolibrary.org/obo/UBERON_6007242) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007242" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### insect embryonic/larval sensillum `http://purl.obolibrary.org/obo/UBERON_6007240` +#### Removed +- [insect embryonic/larval sensillum](http://purl.obolibrary.org/obo/UBERON_6007240) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007240" + +#### Added +- [insect embryonic/larval sensillum](http://purl.obolibrary.org/obo/UBERON_6007240) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007240" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### insect larval head `http://purl.obolibrary.org/obo/UBERON_6001730` +#### Removed +- [insect larval head](http://purl.obolibrary.org/obo/UBERON_6001730) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00001730" + +#### Added +- [insect larval head](http://purl.obolibrary.org/obo/UBERON_6001730) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00001730" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### insect larval sense organ `http://purl.obolibrary.org/obo/UBERON_6002639` +#### Removed +- [insect larval sense organ](http://purl.obolibrary.org/obo/UBERON_6002639) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00002639" + +#### Added +- [insect larval sense organ](http://purl.obolibrary.org/obo/UBERON_6002639) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00002639" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### insect larval tagma `http://purl.obolibrary.org/obo/UBERON_6001728` +#### Removed +- [insect larval tagma](http://purl.obolibrary.org/obo/UBERON_6001728) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00001728" + +#### Added +- [insect larval tagma](http://purl.obolibrary.org/obo/UBERON_6001728) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00001728" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### integument `http://purl.obolibrary.org/obo/UBERON_0002199` +#### Removed +- [integument](http://purl.obolibrary.org/obo/UBERON_0002199) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "integumentum commune" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:74657" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [integument](http://purl.obolibrary.org/obo/UBERON_0002199) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "integumentum commune" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:74657" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### integumental system `http://purl.obolibrary.org/obo/UBERON_0002416` +#### Removed +- [integumental system](http://purl.obolibrary.org/obo/UBERON_0002416) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "integumentum commune" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Integumentary_system" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [integumental system](http://purl.obolibrary.org/obo/UBERON_0002416) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00004969" + +#### Added +- [integumental system](http://purl.obolibrary.org/obo/UBERON_0002416) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00004969" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + +- [integumental system](http://purl.obolibrary.org/obo/UBERON_0002416) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "integumentum commune" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Integumentary_system" + + +### integumentary adnexa `http://purl.obolibrary.org/obo/UBERON_0006003` +#### Removed +- [integumentary adnexa](http://purl.obolibrary.org/obo/UBERON_0006003) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "adnexae cutis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Skin_appendage" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [integumentary adnexa](http://purl.obolibrary.org/obo/UBERON_0006003) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "adnexae cutis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Skin_appendage" + + +### intercarpal joint `http://purl.obolibrary.org/obo/UBERON_0011132` + +#### Added +- [intercarpal joint](http://purl.obolibrary.org/obo/UBERON_0011132) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D050824" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [LexicalMatching](https://w3id.org/semapv/vocab/LexicalMatching) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### intercellular bridge `http://purl.obolibrary.org/obo/GO_0045171` +#### Removed +- [intercellular bridge](http://purl.obolibrary.org/obo/GO_0045171) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "cellular_component" + +- [intercellular bridge](http://purl.obolibrary.org/obo/GO_0045171) [label](http://www.w3.org/2000/01/rdf-schema#label) "intercellular bridge" + +- [intercellular bridge](http://purl.obolibrary.org/obo/GO_0045171) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0045171" + +- [intercellular bridge](http://purl.obolibrary.org/obo/GO_0045171) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A direct connection between the cytoplasm of two cells that is formed following the completion of cleavage furrow ingression during cell division. They are usually present only briefly prior to completion of cytokinesis. However, in some cases, such as the bridges between germ cells during their development, they become stabilised." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:9635420" + +- Class: [intercellular bridge](http://purl.obolibrary.org/obo/GO_0045171) + +- [intercellular bridge](http://purl.obolibrary.org/obo/GO_0045171) SubClassOf [cellular anatomical entity](http://purl.obolibrary.org/obo/GO_0110165) + + + +### intercellular bridge organization `http://purl.obolibrary.org/obo/GO_0043063` +#### Removed +- [intercellular bridge organization](http://purl.obolibrary.org/obo/GO_0043063) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [intercellular bridge organization](http://purl.obolibrary.org/obo/GO_0043063) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the intracellular bridge. An intracellular bridge is a direct link between the cytoplasms of sister cells that allows cells to communicate with one another." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:jid" + +- [intercellular bridge organization](http://purl.obolibrary.org/obo/GO_0043063) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0043063" + +- [intercellular bridge organization](http://purl.obolibrary.org/obo/GO_0043063) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "intercellular bridge organisation" + +- [intercellular bridge organization](http://purl.obolibrary.org/obo/GO_0043063) [label](http://www.w3.org/2000/01/rdf-schema#label) "intercellular bridge organization" + +- [intercellular bridge organization](http://purl.obolibrary.org/obo/GO_0043063) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "intercellular bridge organization and biogenesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- Class: [intercellular bridge organization](http://purl.obolibrary.org/obo/GO_0043063) + +- [intercellular bridge organization](http://purl.obolibrary.org/obo/GO_0043063) EquivalentTo [cellular component organization](http://purl.obolibrary.org/obo/GO_0016043) and ([results in organization of](http://purl.obolibrary.org/obo/RO_0002592) some [intercellular bridge](http://purl.obolibrary.org/obo/GO_0045171)) + +- [intercellular bridge organization](http://purl.obolibrary.org/obo/GO_0043063) SubClassOf [results in organization of](http://purl.obolibrary.org/obo/RO_0002592) some [intercellular bridge](http://purl.obolibrary.org/obo/GO_0045171) + +- [intercellular bridge organization](http://purl.obolibrary.org/obo/GO_0043063) SubClassOf [extracellular structure organization](http://purl.obolibrary.org/obo/GO_0043062) + + + +### intercostal nerve `http://purl.obolibrary.org/obo/UBERON_0003727` +#### Removed +- [intercostal nerve](http://purl.obolibrary.org/obo/UBERON_0003727) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nervi intercostales" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Intercostal_nerves" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [intercostal nerve](http://purl.obolibrary.org/obo/UBERON_0003727) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nervi intercostales" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Intercostal_nerves" + + +### interlobar artery `http://purl.obolibrary.org/obo/UBERON_0009885` +#### Removed +- [interlobar artery](http://purl.obolibrary.org/obo/UBERON_0009885) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteriae interlobares renis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Interlobar_arteries" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [interlobar artery](http://purl.obolibrary.org/obo/UBERON_0009885) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteriae interlobares renis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Interlobar_arteries" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### interlobar vein `http://purl.obolibrary.org/obo/UBERON_0009887` +#### Removed +- [interlobar vein](http://purl.obolibrary.org/obo/UBERON_0009887) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "venae interlobares renis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Interlobar_veins" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [interlobar vein](http://purl.obolibrary.org/obo/UBERON_0009887) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "venae interlobares renis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Interlobar_veins" + + +### interlobular artery `http://purl.obolibrary.org/obo/UBERON_0004723` +#### Removed +- [interlobular artery](http://purl.obolibrary.org/obo/UBERON_0004723) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteriae interlobulares renis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Interlobular_arteries" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [interlobular artery](http://purl.obolibrary.org/obo/UBERON_0004723) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteriae corticales radiatae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Interlobular_arteries" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [interlobular artery](http://purl.obolibrary.org/obo/UBERON_0004723) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteriae interlobulares renis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Interlobular_arteries" + +- [interlobular artery](http://purl.obolibrary.org/obo/UBERON_0004723) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteriae corticales radiatae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Interlobular_arteries" + + +### interlobular duct of salivary gland `http://purl.obolibrary.org/obo/UBERON_0035053` +#### Removed +- [interlobular duct of salivary gland](http://purl.obolibrary.org/obo/UBERON_0035053) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0006341" + - [contributor](http://purl.org/dc/terms/contributor) "https://orcid.org/0000-0003-4423-4370" + + + +### intermediate hypothalamic region `http://purl.obolibrary.org/obo/UBERON_0002555` +#### Removed +- [intermediate hypothalamic region](http://purl.obolibrary.org/obo/UBERON_0002555) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "area hypothalamica intermedia" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:62028" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [intermediate hypothalamic region](http://purl.obolibrary.org/obo/UBERON_0002555) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "regio hypothalamica intermedia" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:392" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [intermediate hypothalamic region](http://purl.obolibrary.org/obo/UBERON_0002555) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "regio hypothalamica intermedia" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:392" + +- [intermediate hypothalamic region](http://purl.obolibrary.org/obo/UBERON_0002555) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "area hypothalamica intermedia" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:62028" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### intermediate mesoderm `http://purl.obolibrary.org/obo/UBERON_0003064` +#### Removed +- [intermediate mesoderm](http://purl.obolibrary.org/obo/UBERON_0003064) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "mesenchyma intermedium" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Intermediate_mesoderm" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [intermediate mesoderm](http://purl.obolibrary.org/obo/UBERON_0003064) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "mesenchyma intermedium" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Intermediate_mesoderm" + + +### intermediate monocyte `http://purl.obolibrary.org/obo/CL_0002393` + +#### Added +- [intermediate monocyte](http://purl.obolibrary.org/obo/CL_0002393) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### internal carotid artery `http://purl.obolibrary.org/obo/UBERON_0001532` +#### Removed +- [internal carotid artery](http://purl.obolibrary.org/obo/UBERON_0001532) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria carotis interna" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Internal_carotid_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [internal carotid artery](http://purl.obolibrary.org/obo/UBERON_0001532) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria carotis interna" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Internal_carotid_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### internal female genitalia `http://purl.obolibrary.org/obo/UBERON_0003975` + +#### Added +- [internal female genitalia](http://purl.obolibrary.org/obo/UBERON_0003975) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [human_reference_atlas](http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas) + +- [internal female genitalia](http://purl.obolibrary.org/obo/UBERON_0003975) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606) + + +### internal genitalia `http://purl.obolibrary.org/obo/UBERON_0004175` + +#### Added +- [internal genitalia](http://purl.obolibrary.org/obo/UBERON_0004175) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [human_reference_atlas](http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas) + +- [internal genitalia](http://purl.obolibrary.org/obo/UBERON_0004175) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606) + + +### internal iliac artery `http://purl.obolibrary.org/obo/UBERON_0001309` +#### Removed +- [internal iliac artery](http://purl.obolibrary.org/obo/UBERON_0001309) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria iliaca interna" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Internal_iliac_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [internal iliac artery](http://purl.obolibrary.org/obo/UBERON_0001309) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria iliaca interna" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Internal_iliac_artery" + + +### internal iliac vein `http://purl.obolibrary.org/obo/UBERON_0001317` +#### Removed +- [internal iliac vein](http://purl.obolibrary.org/obo/UBERON_0001317) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "v. iliaca interna" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Internal_iliac_vein" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [internal iliac vein](http://purl.obolibrary.org/obo/UBERON_0001317) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "v. hypogastrica" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Internal_iliac_vein" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [internal iliac vein](http://purl.obolibrary.org/obo/UBERON_0001317) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "v. hypogastrica" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Internal_iliac_vein" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [internal iliac vein](http://purl.obolibrary.org/obo/UBERON_0001317) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "v. iliaca interna" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Internal_iliac_vein" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### internal jugular vein `http://purl.obolibrary.org/obo/UBERON_0001586` +#### Removed +- [internal jugular vein](http://purl.obolibrary.org/obo/UBERON_0001586) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vena jugularis interna" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Internal_jugular_vein" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [internal jugular vein](http://purl.obolibrary.org/obo/UBERON_0001586) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vena jugularis interna" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Internal_jugular_vein" + + +### internal pudendal vein `http://purl.obolibrary.org/obo/UBERON_0018252` +#### Removed +- [internal pudendal vein](http://purl.obolibrary.org/obo/UBERON_0018252) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "vena pudenda interna" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Internal_pudendal_veins" + +#### Added +- [internal pudendal vein](http://purl.obolibrary.org/obo/UBERON_0018252) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "vena pudenda interna" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Internal_pudendal_veins" + + +### internal thoracic artery `http://purl.obolibrary.org/obo/UBERON_0002456` +#### Removed +- [internal thoracic artery](http://purl.obolibrary.org/obo/UBERON_0002456) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria mammaria interna" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Internal_thoracic_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [internal thoracic artery](http://purl.obolibrary.org/obo/UBERON_0002456) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria thoracica interna" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Internal_thoracic_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [internal thoracic artery](http://purl.obolibrary.org/obo/UBERON_0002456) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria mammaria interna" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Internal_thoracic_artery" + +- [internal thoracic artery](http://purl.obolibrary.org/obo/UBERON_0002456) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria thoracica interna" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Internal_thoracic_artery" + + +### internal urethral orifice `http://purl.obolibrary.org/obo/UBERON_0012242` +#### Removed +- [internal urethral orifice](http://purl.obolibrary.org/obo/UBERON_0012242) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ostium orificium internum" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [internal urethral orifice](http://purl.obolibrary.org/obo/UBERON_0012242) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "orificium urethrae internum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MP:0011782" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [internal urethral orifice](http://purl.obolibrary.org/obo/UBERON_0012242) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ostium urethrae internum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Internal_urethral_orifice" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [internal urethral orifice](http://purl.obolibrary.org/obo/UBERON_0012242) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "orificium urethrae internum" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MP:0011782" + +- [internal urethral orifice](http://purl.obolibrary.org/obo/UBERON_0012242) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ostium orificium internum" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [internal urethral orifice](http://purl.obolibrary.org/obo/UBERON_0012242) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ostium urethrae internum" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Internal_urethral_orifice" + + +### interneuron `http://purl.obolibrary.org/obo/CL_0000099` + +#### Added +- [interneuron](http://purl.obolibrary.org/obo/CL_0000099) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### interstitial cell of Cajal `http://purl.obolibrary.org/obo/CL_0002088` + +#### Added +- [interstitial cell of Cajal](http://purl.obolibrary.org/obo/CL_0002088) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### interstitial cell of ovary `http://purl.obolibrary.org/obo/CL_0002094` + +#### Added +- [interstitial cell of ovary](http://purl.obolibrary.org/obo/CL_0002094) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### interstitial extravillous trophoblast cell `http://purl.obolibrary.org/obo/CL_4033062` + +#### Added +- [interstitial extravillous trophoblast cell](http://purl.obolibrary.org/obo/CL_4033062) [label](http://www.w3.org/2000/01/rdf-schema#label) "interstitial extravillous trophoblast cell" + +- [interstitial extravillous trophoblast cell](http://purl.obolibrary.org/obo/CL_4033062) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A trophoblast cell that invades the uterine wall to anchor the placenta to the uterus. An interstitial extravillous trophoblast cell differentiates from an extravillous trophoblast cell, becoming hyperchromatic and changing its morphology to a fibroblast-like spindle-shaped cell. In humans, this cell can be distinguished by the expression of placental-specific protein 8, which stimulates migration." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:37630754" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "doi:10.1007/978-3-030-84725-8" + +- [interstitial extravillous trophoblast cell](http://purl.obolibrary.org/obo/CL_4033062) [contributor](http://purl.org/dc/terms/contributor) [0000-0001-6677-8489](https://orcid.org/0000-0001-6677-8489) + +- [interstitial extravillous trophoblast cell](http://purl.obolibrary.org/obo/CL_4033062) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "iEVT" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:37630754" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [abbreviation](http://purl.obolibrary.org/obo/OMO_0003000) + +- [interstitial extravillous trophoblast cell](http://purl.obolibrary.org/obo/CL_4033062) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "interstitial extravillous trophoblast" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:37630754" + +- [interstitial extravillous trophoblast cell](http://purl.obolibrary.org/obo/CL_4033062) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "invasive interstitial extravillous trophoblast cell" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "doi:10.1007/978-3-030-84725-8" + +- [interstitial extravillous trophoblast cell](http://purl.obolibrary.org/obo/CL_4033062) [date](http://purl.org/dc/terms/date) "2024-01-08T15:43:15Z"^^[dateTime](http://www.w3.org/2001/XMLSchema#dateTime) + +- [interstitial extravillous trophoblast cell](http://purl.obolibrary.org/obo/CL_4033062) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "interstitial trophoblast" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:11337369" + +- Class: [interstitial extravillous trophoblast cell](http://purl.obolibrary.org/obo/CL_4033062) + +- [interstitial extravillous trophoblast cell](http://purl.obolibrary.org/obo/CL_4033062) SubClassOf [trophoblast cell](http://purl.obolibrary.org/obo/CL_0000351) + +- [interstitial extravillous trophoblast cell](http://purl.obolibrary.org/obo/CL_4033062) SubClassOf [develops from](http://purl.obolibrary.org/obo/RO_0002202) some [extravillous trophoblast](http://purl.obolibrary.org/obo/CL_0008036) + + +### intertarsal joint `http://purl.obolibrary.org/obo/UBERON_0008447` +#### Removed +- [intertarsal joint](http://purl.obolibrary.org/obo/UBERON_0008447) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "articulationes intertarsales" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Intertarsal_articulations" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [intertarsal joint](http://purl.obolibrary.org/obo/UBERON_0008447) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "articulationes intertarsales" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Intertarsal_articulations" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### interventricular septum `http://purl.obolibrary.org/obo/UBERON_0002094` +#### Removed +- [interventricular septum](http://purl.obolibrary.org/obo/UBERON_0002094) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "s. interventriculare cordis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Interventricular_septum" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [interventricular septum](http://purl.obolibrary.org/obo/UBERON_0002094) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "s. interventriculare cordis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Interventricular_septum" + + +### interventricular septum membranous part `http://purl.obolibrary.org/obo/UBERON_0004666` +#### Removed +- [interventricular septum membranous part](http://purl.obolibrary.org/obo/UBERON_0004666) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pars membranacea septi interventricularis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:7135" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [interventricular septum membranous part](http://purl.obolibrary.org/obo/UBERON_0004666) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pars membranacea septi interventricularis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:7135" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### interventricular septum muscular part `http://purl.obolibrary.org/obo/UBERON_0004667` +#### Removed +- [interventricular septum muscular part](http://purl.obolibrary.org/obo/UBERON_0004667) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pars muscularis septi interventricularis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:7134" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [interventricular septum muscular part](http://purl.obolibrary.org/obo/UBERON_0004667) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "septum membranaceum" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [interventricular septum muscular part](http://purl.obolibrary.org/obo/UBERON_0004667) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "septum membranaceum" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [interventricular septum muscular part](http://purl.obolibrary.org/obo/UBERON_0004667) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pars muscularis septi interventricularis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:7134" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### intervertebral disk `http://purl.obolibrary.org/obo/UBERON_0001066` +#### Removed +- [intervertebral disk](http://purl.obolibrary.org/obo/UBERON_0001066) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "discus intervertebralis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:10446" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [intervertebral disk](http://purl.obolibrary.org/obo/UBERON_0001066) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "discus intervertebralis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:10446" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### intestinal crypt stem cell `http://purl.obolibrary.org/obo/CL_0002250` + +#### Added +- [intestinal crypt stem cell](http://purl.obolibrary.org/obo/CL_0002250) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### intestinal crypt stem cell of colon `http://purl.obolibrary.org/obo/CL_0009043` + +#### Added +- [intestinal crypt stem cell of colon](http://purl.obolibrary.org/obo/CL_0009043) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### intestinal crypt stem cell of large intestine `http://purl.obolibrary.org/obo/CL_0009016` + +#### Added +- [intestinal crypt stem cell of large intestine](http://purl.obolibrary.org/obo/CL_0009016) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### intestinal crypt stem cell of small intestine `http://purl.obolibrary.org/obo/CL_0009017` + +#### Added +- [intestinal crypt stem cell of small intestine](http://purl.obolibrary.org/obo/CL_0009017) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### intestinal enteroendocrine cell `http://purl.obolibrary.org/obo/CL_1001516` + +#### Added +- [intestinal enteroendocrine cell](http://purl.obolibrary.org/obo/CL_1001516) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### intestinal epithelial cell `http://purl.obolibrary.org/obo/CL_0002563` + +#### Added +- [intestinal epithelial cell](http://purl.obolibrary.org/obo/CL_0002563) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### intestinal tuft cell `http://purl.obolibrary.org/obo/CL_0019032` + +#### Added +- [intestinal tuft cell](http://purl.obolibrary.org/obo/CL_0019032) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### intestinal villus `http://purl.obolibrary.org/obo/UBERON_0001213` +#### Removed +- [intestinal villus](http://purl.obolibrary.org/obo/UBERON_0001213) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "villi intestinales" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Intestinal_villus" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [intestinal villus](http://purl.obolibrary.org/obo/UBERON_0001213) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "villi intestinales" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Intestinal_villus" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### intestine goblet cell `http://purl.obolibrary.org/obo/CL_0019031` + +#### Added +- [intestine goblet cell](http://purl.obolibrary.org/obo/CL_0019031) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### intracellular nitric oxide homeostasis `http://purl.obolibrary.org/obo/GO_0033484` +#### Removed +- [intracellular nitric oxide homeostasis](http://purl.obolibrary.org/obo/GO_0033484) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0033484" + +- [intracellular nitric oxide homeostasis](http://purl.obolibrary.org/obo/GO_0033484) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) "https://github.com/geneontology/go-ontology/issues/24224"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + +- [intracellular nitric oxide homeostasis](http://purl.obolibrary.org/obo/GO_0033484) [has_broad_synonym](http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym) "NO homeostasis" + +- [intracellular nitric oxide homeostasis](http://purl.obolibrary.org/obo/GO_0033484) [label](http://www.w3.org/2000/01/rdf-schema#label) "intracellular nitric oxide homeostasis" + +- [intracellular nitric oxide homeostasis](http://purl.obolibrary.org/obo/GO_0033484) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cellular nitric oxide homeostasis" + +- [intracellular nitric oxide homeostasis](http://purl.obolibrary.org/obo/GO_0033484) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A homeostatic process involved in the maintenance of a steady state level of nitric oxide within a cell." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- [intracellular nitric oxide homeostasis](http://purl.obolibrary.org/obo/GO_0033484) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [intracellular nitric oxide homeostasis](http://purl.obolibrary.org/obo/GO_0033484) [has_broad_synonym](http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym) "nitric oxide homeostasis" + +- Class: [intracellular nitric oxide homeostasis](http://purl.obolibrary.org/obo/GO_0033484) + +- [intracellular nitric oxide homeostasis](http://purl.obolibrary.org/obo/GO_0033484) EquivalentTo [intracellular chemical homeostasis](http://purl.obolibrary.org/obo/GO_0055082) and ([regulates levels of](http://purl.obolibrary.org/obo/RO_0002332) some [CHEBI_16480](http://purl.obolibrary.org/obo/CHEBI_16480)) + +- [intracellular nitric oxide homeostasis](http://purl.obolibrary.org/obo/GO_0033484) SubClassOf [intracellular chemical homeostasis](http://purl.obolibrary.org/obo/GO_0055082) + +- [intracellular nitric oxide homeostasis](http://purl.obolibrary.org/obo/GO_0033484) SubClassOf [regulates levels of](http://purl.obolibrary.org/obo/RO_0002332) some [CHEBI_16480](http://purl.obolibrary.org/obo/CHEBI_16480) + + + +### intracellular protein transport `http://purl.obolibrary.org/obo/GO_0006886` +#### Removed +- [intracellular protein transport](http://purl.obolibrary.org/obo/GO_0006886) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [prokaryote_subset](http://purl.obolibrary.org/obo/go#prokaryote_subset) + +#### Added +- [intracellular protein transport](http://purl.obolibrary.org/obo/GO_0006886) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_prokaryote](http://purl.obolibrary.org/obo/go#goslim_prokaryote) + + +### intracellular signal transduction `http://purl.obolibrary.org/obo/GO_0035556` +#### Removed +- [intracellular signal transduction](http://purl.obolibrary.org/obo/GO_0035556) [has narrow synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "intracellular protein kinase cascade" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:signaling" + +- [intracellular signal transduction](http://purl.obolibrary.org/obo/GO_0035556) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "intracellular signaling chain" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:3527303782" + +- [intracellular signal transduction](http://purl.obolibrary.org/obo/GO_0035556) [has narrow synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "protein kinase cascade" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:signaling" + +- [intracellular signal transduction](http://purl.obolibrary.org/obo/GO_0035556) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "signal transduction via intracellular signaling cascade" + + + +### intracellular signal transduction involved in positive regulation of cell growth `http://purl.obolibrary.org/obo/GO_1905427` +#### Removed +- [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) [has narrow synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "intracellular signal transduction pathway involved in upregulation of cell growth" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "intracellular signaling cascade involved in positive regulation of cell growth" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) [has narrow synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "intracellular protein kinase cascade involved in stimulation of cell growth" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) [creation date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2016-09-07T18:15:01Z" + +- [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) [has narrow synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "signal transmission via intracellular cascade involved in up regulation of cell growth" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) [has narrow synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "intracellular signal transduction involved in activation of cell growth" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) [has narrow synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "intracellular signal transduction pathway involved in up regulation of cell growth" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "intracellular signal transduction involved in up-regulation of cell growth" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "intracellular signaling chain involved in up-regulation of cell growth" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "intracellular signal transduction involved in up regulation of cell growth" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "intracellular signaling pathway involved in up-regulation of cell growth" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) [has narrow synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "intracellular protein kinase cascade involved in up-regulation of cell growth" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) [has narrow synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "intracellular signaling chain involved in stimulation of cell growth" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) [has narrow synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "intracellular protein kinase cascade involved in up regulation of cell growth" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) [has narrow synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "protein kinase cascade involved in up regulation of cell growth" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) [has narrow synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "intracellular signaling chain involved in activation of cell growth" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "signal transduction via intracellular signaling cascade involved in up regulation of cell growth" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "intracellular signaling cascade involved in up-regulation of cell growth" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) [has narrow synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "intracellular signal transduction pathway involved in positive regulation of cell growth" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) [has narrow synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "intracellular protein kinase cascade involved in upregulation of cell growth" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) [has narrow synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "intracellular signal transduction pathway involved in up-regulation of cell growth" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1905427" + +- [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) [has narrow synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "intracellular protein kinase cascade involved in activation of cell growth" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "intracellular signaling pathway involved in activation of cell growth" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) [label](http://www.w3.org/2000/01/rdf-schema#label) "intracellular signal transduction involved in positive regulation of cell growth" + +- [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any intracellular signal transduction that is involved in positive regulation of cell growth." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GO_REF:0000060" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:15917811" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:vw" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:al" + +- [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "signal transduction via intracellular signaling cascade involved in positive regulation of cell growth" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "intracellular signaling cascade involved in stimulation of cell growth" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) [has narrow synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "protein kinase cascade involved in upregulation of cell growth" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "intracellular signaling cascade involved in activation of cell growth" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) [has narrow synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "intracellular signal transduction pathway involved in activation of cell growth" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) [has narrow synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "intracellular protein kinase cascade involved in positive regulation of cell growth" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) [has narrow synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "protein kinase cascade involved in activation of cell growth" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "intracellular signaling pathway involved in stimulation of cell growth" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "intracellular signaling chain involved in upregulation of cell growth" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) [has narrow synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "protein kinase cascade involved in stimulation of cell growth" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) [has narrow synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "signal transmission via intracellular cascade involved in upregulation of cell growth" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) [created by](http://www.geneontology.org/formats/oboInOwl#created_by) "dph" + +- [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) [has narrow synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "protein kinase cascade involved in positive regulation of cell growth" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "intracellular signaling chain involved in positive regulation of cell growth" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "intracellular signaling cascade involved in up regulation of cell growth" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "intracellular signaling cascade involved in upregulation of cell growth" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "signal transduction via intracellular signaling cascade involved in activation of cell growth" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "intracellular signal transduction involved in upregulation of cell growth" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) [has narrow synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "signal transmission via intracellular cascade involved in activation of cell growth" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) [has narrow synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "intracellular signal transduction pathway involved in stimulation of cell growth" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) [has narrow synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "signal transmission via intracellular cascade involved in positive regulation of cell growth" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "intracellular signaling pathway involved in up regulation of cell growth" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) [has narrow synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "signal transmission via intracellular cascade involved in up-regulation of cell growth" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) [has narrow synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "protein kinase cascade involved in up-regulation of cell growth" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "signal transduction via intracellular signaling cascade involved in upregulation of cell growth" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) [has narrow synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "intracellular signal transduction involved in stimulation of cell growth" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "intracellular signaling chain involved in up regulation of cell growth" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "intracellular signaling pathway involved in upregulation of cell growth" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "signal transduction via intracellular signaling cascade involved in up-regulation of cell growth" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "intracellular signaling pathway involved in positive regulation of cell growth" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "signal transduction via intracellular signaling cascade involved in stimulation of cell growth" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) [has narrow synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "signal transmission via intracellular cascade involved in stimulation of cell growth" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- Class: [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) + +- [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) EquivalentTo [intracellular signal transduction](http://purl.obolibrary.org/obo/GO_0035556) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_0030307)) + +- [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) SubClassOf [intracellular signal transduction](http://purl.obolibrary.org/obo/GO_0035556) + +- [intracellular signal transduction involved in positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_1905427) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [positive regulation of cell growth](http://purl.obolibrary.org/obo/GO_0030307) + + + +### intracellular signaling cassette `http://purl.obolibrary.org/obo/GO_0141124` + +#### Added +- [intracellular signaling cassette](http://purl.obolibrary.org/obo/GO_0141124) [label](http://www.w3.org/2000/01/rdf-schema#label) "intracellular signaling cassette" + +- [intracellular signaling cassette](http://purl.obolibrary.org/obo/GO_0141124) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) "https://github.com/geneontology/go-ontology/issues/26557"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + +- [intracellular signaling cassette](http://purl.obolibrary.org/obo/GO_0141124) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [intracellular signaling cassette](http://purl.obolibrary.org/obo/GO_0141124) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An intracellular signaling module that is part of larger signaling pathways that can be initiated either intracellularly or by cell surface receptors. Intracellular signaling cassettes are discrete signaling units that are often shared by multiple signaling pathways." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:pg" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ha" + +- [intracellular signaling cassette](http://purl.obolibrary.org/obo/GO_0141124) [creation date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2023-12-04T14:13:20Z" + +- [intracellular signaling cassette](http://purl.obolibrary.org/obo/GO_0141124) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0141124" + +- [intracellular signaling cassette](http://purl.obolibrary.org/obo/GO_0141124) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "intracellular signaling module" + +- [intracellular signaling cassette](http://purl.obolibrary.org/obo/GO_0141124) [created by](http://www.geneontology.org/formats/oboInOwl#created_by) "pg" + +- [intracellular signaling cassette](http://purl.obolibrary.org/obo/GO_0141124) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "intracellular signaling cascade" + +- Class: [intracellular signaling cassette](http://purl.obolibrary.org/obo/GO_0141124) + +- [intracellular signaling cassette](http://purl.obolibrary.org/obo/GO_0141124) SubClassOf [intracellular signal transduction](http://purl.obolibrary.org/obo/GO_0035556) + + +### intraepithelial lymphocyte `http://purl.obolibrary.org/obo/CL_0002496` + +#### Added +- [intraepithelial lymphocyte](http://purl.obolibrary.org/obo/CL_0002496) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### intrahepatic cholangiocyte `http://purl.obolibrary.org/obo/CL_0002538` + +#### Added +- [intrahepatic cholangiocyte](http://purl.obolibrary.org/obo/CL_0002538) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### intralobular bile duct `http://purl.obolibrary.org/obo/UBERON_0001282` +#### Removed +- [intralobular bile duct](http://purl.obolibrary.org/obo/UBERON_0001282) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ductus interlobularis bilifer" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:17545" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [intralobular bile duct](http://purl.obolibrary.org/obo/UBERON_0001282) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ductus interlobularis bilifer" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:17545" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### intromittent organ `http://purl.obolibrary.org/obo/UBERON_0008811` +#### Removed +- [intromittent organ](http://purl.obolibrary.org/obo/UBERON_0008811) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00004850" + +#### Added +- [intromittent organ](http://purl.obolibrary.org/obo/UBERON_0008811) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00004850" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### ionocyte `http://purl.obolibrary.org/obo/CL_0005006` + +#### Added +- [ionocyte](http://purl.obolibrary.org/obo/CL_0005006) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### iris epithelium `http://purl.obolibrary.org/obo/UBERON_0002506` +#### Removed +- [iris epithelium](http://purl.obolibrary.org/obo/UBERON_0002506) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "epithelium pigmentosum iridis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:58517" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [iris epithelium](http://purl.obolibrary.org/obo/UBERON_0002506) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "epithelium pigmentosum iridis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:58517" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### irregular bone `http://purl.obolibrary.org/obo/UBERON_0008001` +#### Removed +- [irregular bone](http://purl.obolibrary.org/obo/UBERON_0008001) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "os irregulare" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Irregular_bone" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [irregular bone](http://purl.obolibrary.org/obo/UBERON_0008001) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "os irregulare" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Irregular_bone" + + +### ischium `http://purl.obolibrary.org/obo/UBERON_0001274` +#### Removed +- [ischium](http://purl.obolibrary.org/obo/UBERON_0001274) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "os ischii" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "AAO:0000860" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Ischium" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [ischium](http://purl.obolibrary.org/obo/UBERON_0001274) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "os ischii" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "AAO:0000860" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Ischium" + + +### island of Calleja `http://purl.obolibrary.org/obo/UBERON_0001881` +#### Removed +- [island of Calleja](http://purl.obolibrary.org/obo/UBERON_0001881) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "insula callejae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Islands_of_Calleja" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [island of Calleja](http://purl.obolibrary.org/obo/UBERON_0001881) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "insulae olfactoriae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Islands_of_Calleja" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [island of Calleja](http://purl.obolibrary.org/obo/UBERON_0001881) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "insula callejae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Islands_of_Calleja" + +- [island of Calleja](http://purl.obolibrary.org/obo/UBERON_0001881) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "insulae olfactoriae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Islands_of_Calleja" + + +### jejunal vein `http://purl.obolibrary.org/obo/UBERON_0001216` +#### Removed +- [jejunal vein](http://purl.obolibrary.org/obo/UBERON_0001216) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "venae jejunales" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Jejunal_veins" + +#### Added +- [jejunal vein](http://purl.obolibrary.org/obo/UBERON_0001216) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "venae jejunales" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Jejunal_veins" + + +### jejunum lamina propria `http://purl.obolibrary.org/obo/UBERON_8600034` + +#### Added +- [jejunum lamina propria](http://purl.obolibrary.org/obo/UBERON_8600034) [id](http://www.geneontology.org/formats/oboInOwl#id) "UBERON:8600034" + +- [jejunum lamina propria](http://purl.obolibrary.org/obo/UBERON_8600034) [date](http://purl.org/dc/terms/date) "2024-01-09T16:36:35Z"^^[dateTime](http://www.w3.org/2001/XMLSchema#dateTime) + +- [jejunum lamina propria](http://purl.obolibrary.org/obo/UBERON_8600034) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "uberon" + +- [jejunum lamina propria](http://purl.obolibrary.org/obo/UBERON_8600034) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A lamina propria that is part of a jejunum." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:9394954" + +- [jejunum lamina propria](http://purl.obolibrary.org/obo/UBERON_8600034) [label](http://www.w3.org/2000/01/rdf-schema#label) "jejunum lamina propria" + +- [jejunum lamina propria](http://purl.obolibrary.org/obo/UBERON_8600034) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "jejunal lamina propria" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:1556433" + +- [jejunum lamina propria](http://purl.obolibrary.org/obo/UBERON_8600034) [contributor](http://purl.org/dc/terms/contributor) [0000-0001-6677-8489](https://orcid.org/0000-0001-6677-8489) + +- [jejunum lamina propria](http://purl.obolibrary.org/obo/UBERON_8600034) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lamina propria of jejunum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22763879" + +- [jejunum lamina propria](http://purl.obolibrary.org/obo/UBERON_8600034) [contributor](http://purl.org/dc/terms/contributor) [0000-0001-8134-3037](https://orcid.org/0000-0001-8134-3037) + +- Class: [jejunum lamina propria](http://purl.obolibrary.org/obo/UBERON_8600034) + +- [jejunum lamina propria](http://purl.obolibrary.org/obo/UBERON_8600034) EquivalentTo [lamina propria](http://purl.obolibrary.org/obo/UBERON_0000030) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [jejunum](http://purl.obolibrary.org/obo/UBERON_0002115)) + +- [jejunum lamina propria](http://purl.obolibrary.org/obo/UBERON_8600034) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [intestinal villus of jejunum](http://purl.obolibrary.org/obo/UBERON_0008343) + +- [jejunum lamina propria](http://purl.obolibrary.org/obo/UBERON_8600034) SubClassOf [lamina propria of small intestine](http://purl.obolibrary.org/obo/UBERON_0001238) + + +### jugular foramen `http://purl.obolibrary.org/obo/UBERON_0005456` +#### Removed +- [jugular foramen](http://purl.obolibrary.org/obo/UBERON_0005456) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D000080869" + +#### Added +- [jugular foramen](http://purl.obolibrary.org/obo/UBERON_0005456) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D000080869" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [author_id](https://w3id.org/sssom/author_id) [0000-0001-9439-5346](https://orcid.org/0000-0001-9439-5346) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### juxtaglomerular apparatus `http://purl.obolibrary.org/obo/UBERON_0002303` +#### Removed +- [juxtaglomerular apparatus](http://purl.obolibrary.org/obo/UBERON_0002303) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "complexus juxtaglomerularis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [juxtaglomerular apparatus](http://purl.obolibrary.org/obo/UBERON_0002303) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "complexus juxtaglomerularis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### keratinized stratified squamous epithelium `http://purl.obolibrary.org/obo/UBERON_0012329` +#### Removed +- [keratinized stratified squamous epithelium](http://purl.obolibrary.org/obo/UBERON_0012329) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "epithelium stratificatum squamosum cornificatum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:45568" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [keratinized stratified squamous epithelium](http://purl.obolibrary.org/obo/UBERON_0012329) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "epithelium stratificatum squamosum cornificatum" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:45568" + + +### keratinocyte `http://purl.obolibrary.org/obo/CL_0000312` + +#### Added +- [keratinocyte](http://purl.obolibrary.org/obo/CL_0000312) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### keratinocyte stem cell `http://purl.obolibrary.org/obo/CL_0002337` + +#### Added +- [keratinocyte stem cell](http://purl.obolibrary.org/obo/CL_0002337) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### keratocyte `http://purl.obolibrary.org/obo/CL_0002363` + +#### Added +- [keratocyte](http://purl.obolibrary.org/obo/CL_0002363) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### kidney afferent arteriole endothelial cell `http://purl.obolibrary.org/obo/CL_1001096` + +#### Added +- [kidney afferent arteriole endothelial cell](http://purl.obolibrary.org/obo/CL_1001096) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### kidney arcuate vein `http://purl.obolibrary.org/obo/UBERON_0004719` +#### Removed +- [kidney arcuate vein](http://purl.obolibrary.org/obo/UBERON_0004719) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "venae arcuatae renis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Arcuate_vein" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [kidney arcuate vein](http://purl.obolibrary.org/obo/UBERON_0004719) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "venae arcuatae renis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Arcuate_vein" + + +### kidney capillary endothelial cell `http://purl.obolibrary.org/obo/CL_1000892` + +#### Added +- [kidney capillary endothelial cell](http://purl.obolibrary.org/obo/CL_1000892) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### kidney capsule `http://purl.obolibrary.org/obo/UBERON_0002015` +#### Removed +- [kidney capsule](http://purl.obolibrary.org/obo/UBERON_0002015) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "capsula fibrosa renis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:66610" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [kidney capsule](http://purl.obolibrary.org/obo/UBERON_0002015) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "capsula fibrosa renis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:66610" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### kidney cell `http://purl.obolibrary.org/obo/CL_1000497` + +#### Added +- [kidney cell](http://purl.obolibrary.org/obo/CL_1000497) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### kidney collecting duct cell `http://purl.obolibrary.org/obo/CL_1001225` + +#### Added +- [kidney collecting duct cell](http://purl.obolibrary.org/obo/CL_1001225) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### kidney collecting duct epithelial cell `http://purl.obolibrary.org/obo/CL_1000454` + +#### Added +- [kidney collecting duct epithelial cell](http://purl.obolibrary.org/obo/CL_1000454) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### kidney collecting duct intercalated cell `http://purl.obolibrary.org/obo/CL_1001432` + +#### Added +- [kidney collecting duct intercalated cell](http://purl.obolibrary.org/obo/CL_1001432) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### kidney collecting duct principal cell `http://purl.obolibrary.org/obo/CL_1001431` + +#### Added +- [kidney collecting duct principal cell](http://purl.obolibrary.org/obo/CL_1001431) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### kidney connecting tubule epithelial cell `http://purl.obolibrary.org/obo/CL_1000768` + +#### Added +- [kidney connecting tubule epithelial cell](http://purl.obolibrary.org/obo/CL_1000768) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### kidney connecting tubule principal cell `http://purl.obolibrary.org/obo/CL_4030018` + +#### Added +- [kidney connecting tubule principal cell](http://purl.obolibrary.org/obo/CL_4030018) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### kidney cortex artery cell `http://purl.obolibrary.org/obo/CL_1001045` + +#### Added +- [kidney cortex artery cell](http://purl.obolibrary.org/obo/CL_1001045) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### kidney cortex tubule cell `http://purl.obolibrary.org/obo/CL_1000615` + +#### Added +- [kidney cortex tubule cell](http://purl.obolibrary.org/obo/CL_1000615) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### kidney distal convoluted tubule epithelial cell `http://purl.obolibrary.org/obo/CL_1000849` + +#### Added +- [kidney distal convoluted tubule epithelial cell](http://purl.obolibrary.org/obo/CL_1000849) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### kidney efferent arteriole endothelial cell `http://purl.obolibrary.org/obo/CL_1001099` + +#### Added +- [kidney efferent arteriole endothelial cell](http://purl.obolibrary.org/obo/CL_1001099) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### kidney epithelial cell `http://purl.obolibrary.org/obo/CL_0002518` + +#### Added +- [kidney epithelial cell](http://purl.obolibrary.org/obo/CL_0002518) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### kidney glomerular epithelial cell `http://purl.obolibrary.org/obo/CL_1000510` + +#### Added +- [kidney glomerular epithelial cell](http://purl.obolibrary.org/obo/CL_1000510) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### kidney interstitial cell `http://purl.obolibrary.org/obo/CL_1000500` + +#### Added +- [kidney interstitial cell](http://purl.obolibrary.org/obo/CL_1000500) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### kidney interstitial fibroblast `http://purl.obolibrary.org/obo/CL_1000692` + +#### Added +- [kidney interstitial fibroblast](http://purl.obolibrary.org/obo/CL_1000692) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### kidney loop of Henle ascending limb epithelial cell `http://purl.obolibrary.org/obo/CL_1001016` + +#### Added +- [kidney loop of Henle ascending limb epithelial cell](http://purl.obolibrary.org/obo/CL_1001016) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### kidney loop of Henle cortical thick ascending limb epithelial cell `http://purl.obolibrary.org/obo/CL_1001109` + +#### Added +- [kidney loop of Henle cortical thick ascending limb epithelial cell](http://purl.obolibrary.org/obo/CL_1001109) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### kidney loop of Henle epithelial cell `http://purl.obolibrary.org/obo/CL_1000909` + +#### Added +- [kidney loop of Henle epithelial cell](http://purl.obolibrary.org/obo/CL_1000909) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### kidney loop of Henle medullary thick ascending limb epithelial cell `http://purl.obolibrary.org/obo/CL_1001108` + +#### Added +- [kidney loop of Henle medullary thick ascending limb epithelial cell](http://purl.obolibrary.org/obo/CL_1001108) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### kidney loop of Henle thick ascending limb epithelial cell `http://purl.obolibrary.org/obo/CL_1001106` + +#### Added +- [kidney loop of Henle thick ascending limb epithelial cell](http://purl.obolibrary.org/obo/CL_1001106) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### kidney loop of Henle thin ascending limb epithelial cell `http://purl.obolibrary.org/obo/CL_1001107` + +#### Added +- [kidney loop of Henle thin ascending limb epithelial cell](http://purl.obolibrary.org/obo/CL_1001107) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### kidney loop of Henle thin descending limb epithelial cell `http://purl.obolibrary.org/obo/CL_1001111` + +#### Added +- [kidney loop of Henle thin descending limb epithelial cell](http://purl.obolibrary.org/obo/CL_1001111) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### kidney outer medulla inner stripe `http://purl.obolibrary.org/obo/UBERON_0004201` +#### Removed +- [kidney outer medulla inner stripe](http://purl.obolibrary.org/obo/UBERON_0004201) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "stria interna medullae renalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:76663" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [kidney outer medulla inner stripe](http://purl.obolibrary.org/obo/UBERON_0004201) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "stria interna medullae renalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:76663" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### kidney outer medulla outer stripe `http://purl.obolibrary.org/obo/UBERON_0004202` +#### Removed +- [kidney outer medulla outer stripe](http://purl.obolibrary.org/obo/UBERON_0004202) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "stria externa medullae renalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:76662" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [kidney outer medulla outer stripe](http://purl.obolibrary.org/obo/UBERON_0004202) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "stria externa medullae renalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:76662" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### kidney pelvis urothelial cell `http://purl.obolibrary.org/obo/CL_1000703` + +#### Added +- [kidney pelvis urothelial cell](http://purl.obolibrary.org/obo/CL_1000703) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### kidney proximal convoluted tubule epithelial cell `http://purl.obolibrary.org/obo/CL_1000838` + +#### Added +- [kidney proximal convoluted tubule epithelial cell](http://purl.obolibrary.org/obo/CL_1000838) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### kidney proximal straight tubule epithelial cell `http://purl.obolibrary.org/obo/CL_1000839` + +#### Added +- [kidney proximal straight tubule epithelial cell](http://purl.obolibrary.org/obo/CL_1000839) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### kidney pyramid `http://purl.obolibrary.org/obo/UBERON_0004200` +#### Removed +- [kidney pyramid](http://purl.obolibrary.org/obo/UBERON_0004200) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "pyramides renales" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Renal_pyramids" + +#### Added +- [kidney pyramid](http://purl.obolibrary.org/obo/UBERON_0004200) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "pyramides renales" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Renal_pyramids" + + +### kidney resident macrophage `http://purl.obolibrary.org/obo/CL_1000698` + +#### Added +- [kidney resident macrophage](http://purl.obolibrary.org/obo/CL_1000698) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### kidney rudiment `http://purl.obolibrary.org/obo/UBERON_0005095` +#### Removed +- [kidney rudiment](http://purl.obolibrary.org/obo/UBERON_0005095) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GO:0072003" + +#### Added +- [kidney rudiment](http://purl.obolibrary.org/obo/UBERON_0005095) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Missing definition for term UBERON:0005095. Please replace it using linked reference." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GO:0072003" + + +### knee joint `http://purl.obolibrary.org/obo/UBERON_0001485` +#### Removed +- [knee joint](http://purl.obolibrary.org/obo/UBERON_0001485) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "articulatio genus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Knee" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [knee joint](http://purl.obolibrary.org/obo/UBERON_0001485) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "articulatio genus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Knee" + + +### koniocellular layer of dorsal nucleus of lateral geniculate body `http://purl.obolibrary.org/obo/UBERON_0013615` +#### Removed +- [koniocellular layer of dorsal nucleus of lateral geniculate body](http://purl.obolibrary.org/obo/UBERON_0013615) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "stratum koniocellulare nuclei dorsalis corporis geniculati lateralis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:76988" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [koniocellular layer of dorsal nucleus of lateral geniculate body](http://purl.obolibrary.org/obo/UBERON_0013615) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "stratum koniocellulare nuclei dorsalis corporis geniculati lateralis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:76988" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### lacrimal apparatus `http://purl.obolibrary.org/obo/UBERON_0001750` +#### Removed +- [lacrimal apparatus](http://purl.obolibrary.org/obo/UBERON_0001750) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "apparatus lacrimalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Lacrimal_apparatus" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [lacrimal apparatus](http://purl.obolibrary.org/obo/UBERON_0001750) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "apparatus lacrimalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Lacrimal_apparatus" + + +### lacrimal artery `http://purl.obolibrary.org/obo/UBERON_0001622` +#### Removed +- [lacrimal artery](http://purl.obolibrary.org/obo/UBERON_0001622) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "a. lacrimalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Lacrimal_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [lacrimal artery](http://purl.obolibrary.org/obo/UBERON_0001622) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "a. lacrimalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Lacrimal_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### lacrimal canaliculus `http://purl.obolibrary.org/obo/UBERON_0001770` +#### Removed +- [lacrimal canaliculus](http://purl.obolibrary.org/obo/UBERON_0001770) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "canaliculus lacrimalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Lacrimal_canaliculi" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [lacrimal canaliculus](http://purl.obolibrary.org/obo/UBERON_0001770) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "canaliculus lacrimalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Lacrimal_canaliculi" + + +### lacrimal gland `http://purl.obolibrary.org/obo/UBERON_0001817` +#### Removed +- [lacrimal gland](http://purl.obolibrary.org/obo/UBERON_0001817) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "glandula lacrimalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Lacrimal_gland" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [lacrimal gland](http://purl.obolibrary.org/obo/UBERON_0001817) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "glandula lacrimalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Lacrimal_gland" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### lacrimal nerve `http://purl.obolibrary.org/obo/UBERON_0011096` +#### Removed +- [lacrimal nerve](http://purl.obolibrary.org/obo/UBERON_0011096) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nervus lacrimalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Lacrimal_nerve" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [lacrimal nerve](http://purl.obolibrary.org/obo/UBERON_0011096) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nervus lacrimalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Lacrimal_nerve" + + +### lacrimal punctum `http://purl.obolibrary.org/obo/UBERON_0010284` +#### Removed +- [lacrimal punctum](http://purl.obolibrary.org/obo/UBERON_0010284) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "puncta lacrimalia" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Lacrimal_punctum" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [lacrimal punctum](http://purl.obolibrary.org/obo/UBERON_0010284) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "puncta lacrimalia" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Lacrimal_punctum" + + +### lacrimal sac `http://purl.obolibrary.org/obo/UBERON_0001351` +#### Removed +- [lacrimal sac](http://purl.obolibrary.org/obo/UBERON_0001351) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "saccus lacrimalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Lacrimal_sac" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [lacrimal sac](http://purl.obolibrary.org/obo/UBERON_0001351) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "saccus lacrimalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Lacrimal_sac" + + +### lactocyte `http://purl.obolibrary.org/obo/CL_0002325` + +#### Added +- [lactocyte](http://purl.obolibrary.org/obo/CL_0002325) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### lamp5 GABAergic cortical interneuron `http://purl.obolibrary.org/obo/CL_4023011` + +#### Added +- [lamp5 GABAergic cortical interneuron](http://purl.obolibrary.org/obo/CL_4023011) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### large intestine goblet cell `http://purl.obolibrary.org/obo/CL_1000320` + +#### Added +- [large intestine goblet cell](http://purl.obolibrary.org/obo/CL_1000320) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### large pre-B-II cell `http://purl.obolibrary.org/obo/CL_0000957` + +#### Added +- [large pre-B-II cell](http://purl.obolibrary.org/obo/CL_0000957) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### larva `http://purl.obolibrary.org/obo/UBERON_0002548` +#### Removed +- [larva](http://purl.obolibrary.org/obo/UBERON_0002548) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D007814" + +- [larva](http://purl.obolibrary.org/obo/UBERON_0002548) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00001727" + +#### Added +- [larva](http://purl.obolibrary.org/obo/UBERON_0002548) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D007814" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [author_id](https://w3id.org/sssom/author_id) [0000-0001-9439-5346](https://orcid.org/0000-0001-9439-5346) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + +- [larva](http://purl.obolibrary.org/obo/UBERON_0002548) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00001727" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### late embryo `http://purl.obolibrary.org/obo/UBERON_0000323` +#### Removed +- [late embryo](http://purl.obolibrary.org/obo/UBERON_0000323) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005333" + +#### Added +- [late embryo](http://purl.obolibrary.org/obo/UBERON_0000323) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005333" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### late pro-B cell `http://purl.obolibrary.org/obo/CL_0002048` + +#### Added +- [late pro-B cell](http://purl.obolibrary.org/obo/CL_0002048) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### late promyelocyte `http://purl.obolibrary.org/obo/CL_0002151` + +#### Added +- [late promyelocyte](http://purl.obolibrary.org/obo/CL_0002151) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### lateral border of scapula `http://purl.obolibrary.org/obo/UBERON_0007173` +#### Removed +- [lateral border of scapula](http://purl.obolibrary.org/obo/UBERON_0007173) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "margo lateralis scapulae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:23239" + +#### Added +- [lateral border of scapula](http://purl.obolibrary.org/obo/UBERON_0007173) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "margo lateralis scapulae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:23239" + + +### lateral ganglionic eminence `http://purl.obolibrary.org/obo/UBERON_0004025` + +#### Added +- [lateral ganglionic eminence](http://purl.obolibrary.org/obo/UBERON_0004025) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "uberon" + +- [lateral ganglionic eminence](http://purl.obolibrary.org/obo/UBERON_0004025) [label](http://www.w3.org/2000/01/rdf-schema#label) "lateral ganglionic eminence" + +- [lateral ganglionic eminence](http://purl.obolibrary.org/obo/UBERON_0004025) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "DHBA:10551" + +- [lateral ganglionic eminence](http://purl.obolibrary.org/obo/UBERON_0004025) [has_broad_synonym](http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym) "LGE" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [abbreviation](http://purl.obolibrary.org/obo/OMO_0003000) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:23375746" + +- [lateral ganglionic eminence](http://purl.obolibrary.org/obo/UBERON_0004025) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A distinct elevation of a transient proliferating cell mass of the fetal subventricular zone; this mass contributes most of its cells to the striatum; however, neocortex, thalamus, septum and olfactory bulb neurons are also partly derived from the LGE." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MP:0004277" + +- [lateral ganglionic eminence](http://purl.obolibrary.org/obo/UBERON_0004025) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PBA:128012822" + +- [lateral ganglionic eminence](http://purl.obolibrary.org/obo/UBERON_0004025) [id](http://www.geneontology.org/formats/oboInOwl#id) "UBERON:0004025" + +- [lateral ganglionic eminence](http://purl.obolibrary.org/obo/UBERON_0004025) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "EMAPA:37470" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "MA:th" + +- [lateral ganglionic eminence](http://purl.obolibrary.org/obo/UBERON_0004025) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [pheno_slim](http://purl.obolibrary.org/obo/uberon/core#pheno_slim) + +- Class: [lateral ganglionic eminence](http://purl.obolibrary.org/obo/UBERON_0004025) + +- [lateral ganglionic eminence](http://purl.obolibrary.org/obo/UBERON_0004025) SubClassOf [embryonic structure](http://purl.obolibrary.org/obo/UBERON_0002050) + +- [lateral ganglionic eminence](http://purl.obolibrary.org/obo/UBERON_0004025) SubClassOf [contributes to morphology of](http://purl.obolibrary.org/obo/RO_0002433) some [ganglionic eminence](http://purl.obolibrary.org/obo/UBERON_0004023) + +- [lateral ganglionic eminence](http://purl.obolibrary.org/obo/UBERON_0004025) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [ganglionic eminence](http://purl.obolibrary.org/obo/UBERON_0004023) + + +### lateral ganglionic eminence derived neuron `http://purl.obolibrary.org/obo/CL_4023035` + +#### Added +- [lateral ganglionic eminence derived neuron](http://purl.obolibrary.org/obo/CL_4023035) [contributor](http://purl.org/dc/terms/contributor) "https://orcid.org/0000-0001-7258-9596" + +- [lateral ganglionic eminence derived neuron](http://purl.obolibrary.org/obo/CL_4023035) [label](http://www.w3.org/2000/01/rdf-schema#label) "lateral ganglionic eminence derived neuron"@en + +- [lateral ganglionic eminence derived neuron](http://purl.obolibrary.org/obo/CL_4023035) [contributor](http://purl.org/dc/terms/contributor) "https://orcid.org/0000-0002-7073-9172" + +- [lateral ganglionic eminence derived neuron](http://purl.obolibrary.org/obo/CL_4023035) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "LGE-derived neuron" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:10377350" + +- [lateral ganglionic eminence derived neuron](http://purl.obolibrary.org/obo/CL_4023035) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A neuron that is derived from a precursor cell in the lateral ganglion eminence." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "wikipediaversioned:Ganglionic_eminence&oldid=1186824360" + +- Class: [lateral ganglionic eminence derived neuron](http://purl.obolibrary.org/obo/CL_4023035) + +- [lateral ganglionic eminence derived neuron](http://purl.obolibrary.org/obo/CL_4023035) EquivalentTo [neuron](http://purl.obolibrary.org/obo/CL_0000540) and ([develops from](http://purl.obolibrary.org/obo/RO_0002202) some [lateral ganglionic eminence](http://purl.obolibrary.org/obo/UBERON_0004025)) + +- [lateral ganglionic eminence derived neuron](http://purl.obolibrary.org/obo/CL_4023035) SubClassOf [neuron](http://purl.obolibrary.org/obo/CL_0000540) + +- [lateral ganglionic eminence derived neuron](http://purl.obolibrary.org/obo/CL_4023035) SubClassOf [develops from](http://purl.obolibrary.org/obo/RO_0002202) some [lateral ganglionic eminence](http://purl.obolibrary.org/obo/UBERON_0004025) + + +### lateral geniculate body `http://purl.obolibrary.org/obo/UBERON_0001926` +#### Removed +- [lateral geniculate body](http://purl.obolibrary.org/obo/UBERON_0001926) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus corporis geniculati lateralis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BAMS:LG" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:352" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [lateral geniculate body](http://purl.obolibrary.org/obo/UBERON_0001926) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "corpus geniculatus lateralis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:352" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [lateral geniculate body](http://purl.obolibrary.org/obo/UBERON_0001926) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "corpus geniculatus lateralis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:352" + +- [lateral geniculate body](http://purl.obolibrary.org/obo/UBERON_0001926) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus corporis geniculati lateralis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BAMS:LG" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:352" + + +### lateral line system `http://purl.obolibrary.org/obo/UBERON_0002540` +#### Removed +- [lateral line system](http://purl.obolibrary.org/obo/UBERON_0002540) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D053403" + +#### Added +- [lateral line system](http://purl.obolibrary.org/obo/UBERON_0002540) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D053403" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [author_id](https://w3id.org/sssom/author_id) [0000-0001-9439-5346](https://orcid.org/0000-0001-9439-5346) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### lateral lingual swelling `http://purl.obolibrary.org/obo/UBERON_0006757` +#### Removed +- [lateral lingual swelling](http://purl.obolibrary.org/obo/UBERON_0006757) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tuberculum linguale laterale" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Lateral_lingual_swelling" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [lateral lingual swelling](http://purl.obolibrary.org/obo/UBERON_0006757) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tuberculum linguale laterale" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Lateral_lingual_swelling" + + +### lateral nasal prominence `http://purl.obolibrary.org/obo/UBERON_0004067` +#### Removed +- [lateral nasal prominence](http://purl.obolibrary.org/obo/UBERON_0004067) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "prominentia nasalis lateralis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Lateral_nasal_prominence" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [lateral nasal prominence](http://purl.obolibrary.org/obo/UBERON_0004067) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "prominentia nasalis lateralis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Lateral_nasal_prominence" + + +### lateral olfactory stria `http://purl.obolibrary.org/obo/UBERON_0001888` +#### Removed +- [lateral olfactory stria](http://purl.obolibrary.org/obo/UBERON_0001888) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tractus olfactorius lateralis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:284" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [lateral olfactory stria](http://purl.obolibrary.org/obo/UBERON_0001888) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "stria olfactoria lateralis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Lateral_olfactory_stria" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:284" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [lateral olfactory stria](http://purl.obolibrary.org/obo/UBERON_0001888) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tractus olfactorius lateralis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ZFA:0000229" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [lateral olfactory stria](http://purl.obolibrary.org/obo/UBERON_0001888) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "stria olfactoria lateralis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Lateral_olfactory_stria" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:284" + +- [lateral olfactory stria](http://purl.obolibrary.org/obo/UBERON_0001888) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tractus olfactorius lateralis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:284" + +- [lateral olfactory stria](http://purl.obolibrary.org/obo/UBERON_0001888) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tractus olfactorius lateralis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ZFA:0000229" + + +### lateral plate mesoderm `http://purl.obolibrary.org/obo/UBERON_0003081` +#### Removed +- [lateral plate mesoderm](http://purl.obolibrary.org/obo/UBERON_0003081) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "mesoderma laminae lateralis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Lateral_plate_mesoderm" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [lateral plate mesoderm](http://purl.obolibrary.org/obo/UBERON_0003081) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "mesoderma laminae lateralis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Lateral_plate_mesoderm" + + +### latissimus dorsi muscle `http://purl.obolibrary.org/obo/UBERON_0001112` +#### Removed +- [latissimus dorsi muscle](http://purl.obolibrary.org/obo/UBERON_0001112) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "musculus latissimus dorsi" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Latissimus_dorsi_muscle" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [latissimus dorsi muscle](http://purl.obolibrary.org/obo/UBERON_0001112) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "musculus latissimus dorsi" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Latissimus_dorsi_muscle" + + +### layer of sclera `http://purl.obolibrary.org/obo/UBERON_0010291` +#### Removed +- [layer of sclera](http://purl.obolibrary.org/obo/UBERON_0010291) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Sclera#Histology" + + + +### left adrenal gland `http://purl.obolibrary.org/obo/UBERON_0001234` +#### Removed +- [left adrenal gland](http://purl.obolibrary.org/obo/UBERON_0001234) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "glandula suprarenalis sinister" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [left adrenal gland](http://purl.obolibrary.org/obo/UBERON_0001234) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "glandula suprarenalis sinister" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### left bundle branch `http://purl.obolibrary.org/obo/UBERON_0005986` +#### Removed +- [left bundle branch](http://purl.obolibrary.org/obo/UBERON_0005986) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "crus sinistrum fasciculi atrioventricularis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:9487" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [left bundle branch](http://purl.obolibrary.org/obo/UBERON_0005986) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "crus sinistrum fasciculi atrioventricularis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:9487" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### left cardiac atrium `http://purl.obolibrary.org/obo/UBERON_0002079` +#### Removed +- [left cardiac atrium](http://purl.obolibrary.org/obo/UBERON_0002079) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "atrium sinistrum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Left_atrium" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [left cardiac atrium](http://purl.obolibrary.org/obo/UBERON_0002079) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "atrium sinistrum" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Left_atrium" + + +### left crus of diaphragm `http://purl.obolibrary.org/obo/UBERON_0014767` + +#### Added +- [left crus of diaphragm](http://purl.obolibrary.org/obo/UBERON_0014767) [label](http://www.w3.org/2000/01/rdf-schema#label) "left crus of diaphragm" + +- [left crus of diaphragm](http://purl.obolibrary.org/obo/UBERON_0014767) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "SCTID:244937004" + +- [left crus of diaphragm](http://purl.obolibrary.org/obo/UBERON_0014767) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "left crus of diaphragm" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:58287" + +- [left crus of diaphragm](http://purl.obolibrary.org/obo/UBERON_0014767) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A crus of diaphragm that is in_the_left_side_of a diaphragm." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "OBOL:automatic" + +- [left crus of diaphragm](http://purl.obolibrary.org/obo/UBERON_0014767) [UBPROP_0000006](http://purl.obolibrary.org/obo/UBPROP_0000006) "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + +- [left crus of diaphragm](http://purl.obolibrary.org/obo/UBERON_0014767) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "uberon" + +- [left crus of diaphragm](http://purl.obolibrary.org/obo/UBERON_0014767) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "left crus of lumbar part of diaphragm" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:58287" + +- [left crus of diaphragm](http://purl.obolibrary.org/obo/UBERON_0014767) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "crus sinistrum diaphragmatis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:58287" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [left crus of diaphragm](http://purl.obolibrary.org/obo/UBERON_0014767) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:58287" + +- [left crus of diaphragm](http://purl.obolibrary.org/obo/UBERON_0014767) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "crus sinistrum (Diaphragma)" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:58287" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [left crus of diaphragm](http://purl.obolibrary.org/obo/UBERON_0014767) [id](http://www.geneontology.org/formats/oboInOwl#id) "UBERON:0014767" + +- Class: [left crus of diaphragm](http://purl.obolibrary.org/obo/UBERON_0014767) + +- [left crus of diaphragm](http://purl.obolibrary.org/obo/UBERON_0014767) EquivalentTo [crus of diaphragm](http://purl.obolibrary.org/obo/UBERON_0014765) and ([in left side of](http://purl.obolibrary.org/obo/BSPO_0000120) some [diaphragm](http://purl.obolibrary.org/obo/UBERON_0001103)) + +- [left crus of diaphragm](http://purl.obolibrary.org/obo/UBERON_0014767) SubClassOf [crus of diaphragm](http://purl.obolibrary.org/obo/UBERON_0014765) + +- [left crus of diaphragm](http://purl.obolibrary.org/obo/UBERON_0014767) SubClassOf [in left side of](http://purl.obolibrary.org/obo/BSPO_0000120) some [diaphragm](http://purl.obolibrary.org/obo/UBERON_0001103) + + +### left hepatic artery `http://purl.obolibrary.org/obo/UBERON_0015481` +#### Removed +- [left hepatic artery](http://purl.obolibrary.org/obo/UBERON_0015481) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ramus sinister (arteria hepatica propria)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:14779" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [left hepatic artery](http://purl.obolibrary.org/obo/UBERON_0015481) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ramus sinister (arteria hepatica propria)" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:14779" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### left hepatic duct `http://purl.obolibrary.org/obo/UBERON_0001177` +#### Removed +- [left hepatic duct](http://purl.obolibrary.org/obo/UBERON_0001177) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ductus hepaticus sinister" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [left hepatic duct](http://purl.obolibrary.org/obo/UBERON_0001177) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ductus hepaticus sinister" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### left lobe of liver `http://purl.obolibrary.org/obo/UBERON_0001115` +#### Removed +- [left lobe of liver](http://purl.obolibrary.org/obo/UBERON_0001115) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "lobus hepatis sinister" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Left_lobe_of_liver" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [left lobe of liver](http://purl.obolibrary.org/obo/UBERON_0001115) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lobus hepaticus sinister" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [left lobe of liver](http://purl.obolibrary.org/obo/UBERON_0001115) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lobus hepaticus sinister" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [left lobe of liver](http://purl.obolibrary.org/obo/UBERON_0001115) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "lobus hepatis sinister" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Left_lobe_of_liver" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### left pulmonary artery `http://purl.obolibrary.org/obo/UBERON_0001652` +#### Removed +- [left pulmonary artery](http://purl.obolibrary.org/obo/UBERON_0001652) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria pulmonalis sinistra" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Left_pulmonary_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [left pulmonary artery](http://purl.obolibrary.org/obo/UBERON_0001652) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria pulmonalis sinistra" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Left_pulmonary_artery" + + +### left subclavian artery `http://purl.obolibrary.org/obo/UBERON_0001584` +#### Removed +- [left subclavian artery](http://purl.obolibrary.org/obo/UBERON_0001584) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "arteria subclavia (sinistra)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:4694" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [left subclavian artery](http://purl.obolibrary.org/obo/UBERON_0001584) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "arteria subclavia (sinistra)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:4694" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### left ventricular trabecular myocardium `http://purl.obolibrary.org/obo/UBERON_0005064` +#### Removed +- [left ventricular trabecular myocardium](http://purl.obolibrary.org/obo/UBERON_0005064) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GO:0003225" + +#### Added +- [left ventricular trabecular myocardium](http://purl.obolibrary.org/obo/UBERON_0005064) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Missing definition for term UBERON:0005064. Please replace it using linked reference." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GO:0003225" + + +### lens epithelial cell `http://purl.obolibrary.org/obo/CL_0002224` + +#### Added +- [lens epithelial cell](http://purl.obolibrary.org/obo/CL_0002224) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### lens fiber `http://purl.obolibrary.org/obo/UBERON_0002444` +#### Removed +- [lens fiber](http://purl.obolibrary.org/obo/UBERON_0002444) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "fibrae lentis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:76827" + +#### Added +- [lens fiber](http://purl.obolibrary.org/obo/UBERON_0002444) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "fibrae lentis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:76827" + + +### lens fiber cell `http://purl.obolibrary.org/obo/CL_0011004` + +#### Added +- [lens fiber cell](http://purl.obolibrary.org/obo/CL_0011004) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### lens placode `http://purl.obolibrary.org/obo/UBERON_0003073` +#### Removed +- [lens placode](http://purl.obolibrary.org/obo/UBERON_0003073) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "placoda lentis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Lens_placode" + +#### Added +- [lens placode](http://purl.obolibrary.org/obo/UBERON_0003073) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "placoda lentis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Lens_placode" + + +### leptomeningeal cell `http://purl.obolibrary.org/obo/CL_0000708` + +#### Added +- [leptomeningeal cell](http://purl.obolibrary.org/obo/CL_0000708) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### leukocyte `http://purl.obolibrary.org/obo/CL_0000738` + +#### Added +- [leukocyte](http://purl.obolibrary.org/obo/CL_0000738) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### levator scapulae muscle `http://purl.obolibrary.org/obo/UBERON_0005461` +#### Removed +- [levator scapulae muscle](http://purl.obolibrary.org/obo/UBERON_0005461) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "musculus levator scapulae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Levator_scapulae_muscle" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [levator scapulae muscle](http://purl.obolibrary.org/obo/UBERON_0005461) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "musculus levator scapulae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Levator_scapulae_muscle" + + +### ligament of sternoclavicular joint `http://purl.obolibrary.org/obo/UBERON_0011875` +#### Removed +- [ligament of sternoclavicular joint](http://purl.obolibrary.org/obo/UBERON_0011875) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ligamentum sternoclavicularis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [ligament of sternoclavicular joint](http://purl.obolibrary.org/obo/UBERON_0011875) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ligamentum sternoclavicularis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### limb `http://purl.obolibrary.org/obo/UBERON_0002101` + +#### Added +- [limb](http://purl.obolibrary.org/obo/UBERON_0002101) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D005121" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [LexicalMatching](https://w3id.org/semapv/vocab/LexicalMatching) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### limb bud `http://purl.obolibrary.org/obo/UBERON_0004347` +#### Removed +- [limb bud](http://purl.obolibrary.org/obo/UBERON_0004347) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "gemmae membrorum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Limb_bud" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [limb bud](http://purl.obolibrary.org/obo/UBERON_0004347) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "gemmae membrorum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Limb_bud" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### limb muscle `http://purl.obolibrary.org/obo/UBERON_0003661` + +#### Added +- [limb muscle](http://purl.obolibrary.org/obo/UBERON_0003661) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [human_reference_atlas](http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas) + +- [limb muscle](http://purl.obolibrary.org/obo/UBERON_0003661) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606) + + +### limbic lobe `http://purl.obolibrary.org/obo/UBERON_0002600` +#### Removed +- [limbic lobe](http://purl.obolibrary.org/obo/UBERON_0002600) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D065726" + +- [limbic lobe](http://purl.obolibrary.org/obo/UBERON_0002600) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "gyrus fornicatus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:834" + +- [limbic lobe](http://purl.obolibrary.org/obo/UBERON_0002600) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "lobus limbicus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Limbic_lobe" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [limbic lobe](http://purl.obolibrary.org/obo/UBERON_0002600) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "lobus limbicus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Limbic_lobe" + +- [limbic lobe](http://purl.obolibrary.org/obo/UBERON_0002600) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D065726" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [author_id](https://w3id.org/sssom/author_id) [0000-0001-9439-5346](https://orcid.org/0000-0001-9439-5346) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + +- [limbic lobe](http://purl.obolibrary.org/obo/UBERON_0002600) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "gyrus fornicatus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:834" + + +### lingual artery `http://purl.obolibrary.org/obo/UBERON_0001610` +#### Removed +- [lingual artery](http://purl.obolibrary.org/obo/UBERON_0001610) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria lingualis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Lingual_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [lingual artery](http://purl.obolibrary.org/obo/UBERON_0001610) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria lingualis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Lingual_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### lip `http://purl.obolibrary.org/obo/UBERON_0001833` +#### Removed +- [lip](http://purl.obolibrary.org/obo/UBERON_0001833) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "labia oris" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Lip" + +#### Added +- [lip](http://purl.obolibrary.org/obo/UBERON_0001833) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "labia oris" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Lip" + + +### lipid binding `http://purl.obolibrary.org/obo/GO_0008289` +#### Removed +- [lipid binding](http://purl.obolibrary.org/obo/GO_0008289) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [prokaryote_subset](http://purl.obolibrary.org/obo/go#prokaryote_subset) + +#### Added +- [lipid binding](http://purl.obolibrary.org/obo/GO_0008289) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_prokaryote](http://purl.obolibrary.org/obo/go#goslim_prokaryote) + + +### lipid metabolic process `http://purl.obolibrary.org/obo/GO_0006629` +#### Removed +- [lipid metabolic process](http://purl.obolibrary.org/obo/GO_0006629) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [prokaryote_subset](http://purl.obolibrary.org/obo/go#prokaryote_subset) + +#### Added +- [lipid metabolic process](http://purl.obolibrary.org/obo/GO_0006629) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_prokaryote](http://purl.obolibrary.org/obo/go#goslim_prokaryote) + + +### liver `http://purl.obolibrary.org/obo/UBERON_0002107` +#### Removed +- [liver](http://purl.obolibrary.org/obo/UBERON_0002107) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "jecur" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Liver" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [liver](http://purl.obolibrary.org/obo/UBERON_0002107) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "iecur" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Liver" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [liver](http://purl.obolibrary.org/obo/UBERON_0002107) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "iecur" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Liver" + +- [liver](http://purl.obolibrary.org/obo/UBERON_0002107) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "jecur" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Liver" + + +### liver dendritic cell `http://purl.obolibrary.org/obo/CL_2000055` + +#### Added +- [liver dendritic cell](http://purl.obolibrary.org/obo/CL_2000055) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### liver lobule `http://purl.obolibrary.org/obo/UBERON_0004647` +#### Removed +- [liver lobule](http://purl.obolibrary.org/obo/UBERON_0004647) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "lobuli hepatis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Lobules_of_liver" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [liver lobule](http://purl.obolibrary.org/obo/UBERON_0004647) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lobulus hepaticus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:14471" + +#### Added +- [liver lobule](http://purl.obolibrary.org/obo/UBERON_0004647) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "lobuli hepatis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Lobules_of_liver" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [liver lobule](http://purl.obolibrary.org/obo/UBERON_0004647) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lobulus hepaticus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:14471" + + +### liver serosa `http://purl.obolibrary.org/obo/UBERON_8400021` +#### Removed +- [liver serosa](http://purl.obolibrary.org/obo/UBERON_8400021) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica serosa hepatis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "https://medical-dictionary.thefreedictionary.com/serosa+of+liver" + + - [synonym_type_property](http://www.geneontology.org/formats/oboInOwl#SynonymTypeProperty) "LATIN" + +#### Added +- [liver serosa](http://purl.obolibrary.org/obo/UBERON_8400021) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica serosa hepatis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "https://medical-dictionary.thefreedictionary.com/serosa+of+liver" + + +### lobar bronchus `http://purl.obolibrary.org/obo/UBERON_0002183` +#### Removed +- [lobar bronchus](http://purl.obolibrary.org/obo/UBERON_0002183) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "bronchi lobaris" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Secondary_bronchus" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [lobar bronchus](http://purl.obolibrary.org/obo/UBERON_0002183) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "bronchi lobaris" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Secondary_bronchus" + + +### lobe of cerebral hemisphere `http://purl.obolibrary.org/obo/UBERON_0016526` +#### Removed +- [lobe of cerebral hemisphere](http://purl.obolibrary.org/obo/UBERON_0016526) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lobi cerebri" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:77800" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [lobe of cerebral hemisphere](http://purl.obolibrary.org/obo/UBERON_0016526) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lobi cerebri" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:77800" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### lobe of thyroid gland `http://purl.obolibrary.org/obo/UBERON_0001118` +#### Removed +- [lobe of thyroid gland](http://purl.obolibrary.org/obo/UBERON_0001118) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "lobuli glandulae thyroideae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Lobes_of_thyroid_gland" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [lobe of thyroid gland](http://purl.obolibrary.org/obo/UBERON_0001118) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lobus glandulae thyroideae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:13367" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [lobe of thyroid gland](http://purl.obolibrary.org/obo/UBERON_0001118) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lobus glandulae thyroideae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:13367" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [lobe of thyroid gland](http://purl.obolibrary.org/obo/UBERON_0001118) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "lobuli glandulae thyroideae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Lobes_of_thyroid_gland" + + +### lobule `http://purl.obolibrary.org/obo/UBERON_0009911` +#### Removed +- [lobule](http://purl.obolibrary.org/obo/UBERON_0009911) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lobulus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:45737" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [lobule](http://purl.obolibrary.org/obo/UBERON_0009911) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lobulus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:45737" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### locus ceruleus `http://purl.obolibrary.org/obo/UBERON_0002148` +#### Removed +- [locus ceruleus](http://purl.obolibrary.org/obo/UBERON_0002148) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nucleus caeruleus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:72478" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [locus ceruleus](http://purl.obolibrary.org/obo/UBERON_0002148) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus loci caerulei" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:583" + +#### Added +- [locus ceruleus](http://purl.obolibrary.org/obo/UBERON_0002148) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nucleus caeruleus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:72478" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [locus ceruleus](http://purl.obolibrary.org/obo/UBERON_0002148) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus loci caerulei" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:583" + + +### loop of Henle `http://purl.obolibrary.org/obo/UBERON_0001288` +#### Removed +- [loop of Henle](http://purl.obolibrary.org/obo/UBERON_0001288) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ansa nephroni" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Loop_of_Henle" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [loop of Henle](http://purl.obolibrary.org/obo/UBERON_0001288) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ansa nephroni" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Loop_of_Henle" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### loose connective tissue `http://purl.obolibrary.org/obo/UBERON_0011825` +#### Removed +- [loose connective tissue](http://purl.obolibrary.org/obo/UBERON_0011825) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "textus connectivus collagenosus laxus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:19783" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [loose connective tissue](http://purl.obolibrary.org/obo/UBERON_0011825) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "textus connectivus laxus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:19783" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [loose connective tissue](http://purl.obolibrary.org/obo/UBERON_0011825) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "textus connectivus laxus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:19783" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [loose connective tissue](http://purl.obolibrary.org/obo/UBERON_0011825) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "textus connectivus collagenosus laxus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:19783" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### lower lip `http://purl.obolibrary.org/obo/UBERON_0001835` +#### Removed +- [lower lip](http://purl.obolibrary.org/obo/UBERON_0001835) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "labium inferius oris" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Lower_lip" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [lower lip](http://purl.obolibrary.org/obo/UBERON_0001835) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "labium inferius oris" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Lower_lip" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### lower urinary tract `http://purl.obolibrary.org/obo/UBERON_0001556` + +#### Added +- [lower urinary tract](http://purl.obolibrary.org/obo/UBERON_0001556) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [human_reference_atlas](http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas) + +- [lower urinary tract](http://purl.obolibrary.org/obo/UBERON_0001556) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606) + + +### lumbosacral nerve plexus `http://purl.obolibrary.org/obo/UBERON_0001815` +#### Removed +- [lumbosacral nerve plexus](http://purl.obolibrary.org/obo/UBERON_0001815) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "plexus lumbosacralis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Lumbosacral_plexus" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [lumbosacral nerve plexus](http://purl.obolibrary.org/obo/UBERON_0001815) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "plexus lumbosacralis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:5907" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [lumbosacral nerve plexus](http://purl.obolibrary.org/obo/UBERON_0001815) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "plexus lumbosacralis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:5907" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [lumbosacral nerve plexus](http://purl.obolibrary.org/obo/UBERON_0001815) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "plexus lumbosacralis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Lumbosacral_plexus" + + +### lumen of open tracheal system trachea `http://purl.obolibrary.org/obo/UBERON_0006832` +#### Removed +- [lumen of open tracheal system trachea](http://purl.obolibrary.org/obo/UBERON_0006832) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007410" + +#### Added +- [lumen of open tracheal system trachea](http://purl.obolibrary.org/obo/UBERON_0006832) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007410" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### luminal cell of prostate epithelium `http://purl.obolibrary.org/obo/CL_0002340` + +#### Added +- [luminal cell of prostate epithelium](http://purl.obolibrary.org/obo/CL_0002340) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### luminal epithelial cell of mammary gland `http://purl.obolibrary.org/obo/CL_0002326` + +#### Added +- [luminal epithelial cell of mammary gland](http://purl.obolibrary.org/obo/CL_0002326) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### luminal layer of epithelium `http://purl.obolibrary.org/obo/UBERON_0011945` +#### Removed +- [luminal layer of epithelium](http://purl.obolibrary.org/obo/UBERON_0011945) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [human_reference_atlas](http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas) + +- [luminal layer of epithelium](http://purl.obolibrary.org/obo/UBERON_0011945) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606) + + + +### lung `http://purl.obolibrary.org/obo/UBERON_0002048` +#### Removed +- [lung](http://purl.obolibrary.org/obo/UBERON_0002048) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pulmo" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [lung](http://purl.obolibrary.org/obo/UBERON_0002048) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pulmo" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### lung bud `http://purl.obolibrary.org/obo/UBERON_0000118` +#### Removed +- [lung bud](http://purl.obolibrary.org/obo/UBERON_0000118) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "gemma pulmonalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Lung_buds" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [lung bud](http://purl.obolibrary.org/obo/UBERON_0000118) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "gemma respiratoria" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Lung_buds" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [lung bud](http://purl.obolibrary.org/obo/UBERON_0000118) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "gemma respiratoria" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Lung_buds" + +- [lung bud](http://purl.obolibrary.org/obo/UBERON_0000118) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "gemma pulmonalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Lung_buds" + + +### lung ciliated cell `http://purl.obolibrary.org/obo/CL_1000271` + +#### Added +- [lung ciliated cell](http://purl.obolibrary.org/obo/CL_1000271) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### lung goblet cell `http://purl.obolibrary.org/obo/CL_1000143` + +#### Added +- [lung goblet cell](http://purl.obolibrary.org/obo/CL_1000143) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### lung macrophage `http://purl.obolibrary.org/obo/CL_1001603` + +#### Added +- [lung macrophage](http://purl.obolibrary.org/obo/CL_1001603) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### lung microvascular endothelial cell `http://purl.obolibrary.org/obo/CL_2000016` + +#### Added +- [lung microvascular endothelial cell](http://purl.obolibrary.org/obo/CL_2000016) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### lung neuroendocrine cell `http://purl.obolibrary.org/obo/CL_1000223` + +#### Added +- [lung neuroendocrine cell](http://purl.obolibrary.org/obo/CL_1000223) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### lung pericyte `http://purl.obolibrary.org/obo/CL_0009089` + +#### Added +- [lung pericyte](http://purl.obolibrary.org/obo/CL_0009089) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### lung secretory cell `http://purl.obolibrary.org/obo/CL_1000272` + +#### Added +- [lung secretory cell](http://purl.obolibrary.org/obo/CL_1000272) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### lymph `http://purl.obolibrary.org/obo/UBERON_0002391` +#### Removed +- [lymph](http://purl.obolibrary.org/obo/UBERON_0002391) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "lympha" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Lymph" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [lymph](http://purl.obolibrary.org/obo/UBERON_0002391) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "lympha" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Lymph" + + +### lymph node `http://purl.obolibrary.org/obo/UBERON_0000029` +#### Removed +- [lymph node](http://purl.obolibrary.org/obo/UBERON_0000029) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nodus lymphaticus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Lymph_node" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [lymph node](http://purl.obolibrary.org/obo/UBERON_0000029) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nodus lymphaticus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Lymph_node" + + +### lymph vasculature `http://purl.obolibrary.org/obo/UBERON_0004536` +#### Removed +- [lymph vasculature](http://purl.obolibrary.org/obo/UBERON_0004536) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "trunci et ductus lymphatici" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:63815" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [lymph vasculature](http://purl.obolibrary.org/obo/UBERON_0004536) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "trunci et ductus lymphatici" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:63815" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### lymphatic vessel `http://purl.obolibrary.org/obo/UBERON_0001473` +#### Removed +- [lymphatic vessel](http://purl.obolibrary.org/obo/UBERON_0001473) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D042601" + +- [lymphatic vessel](http://purl.obolibrary.org/obo/UBERON_0001473) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vas lymphaticum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Lymphatic_vessel" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [lymphatic vessel](http://purl.obolibrary.org/obo/UBERON_0001473) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D042601" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [author_id](https://w3id.org/sssom/author_id) [0000-0001-9439-5346](https://orcid.org/0000-0001-9439-5346) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + +- [lymphatic vessel](http://purl.obolibrary.org/obo/UBERON_0001473) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vas lymphaticum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Lymphatic_vessel" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### lymphocyte `http://purl.obolibrary.org/obo/CL_0000542` +#### Removed +- [lymphocyte](http://purl.obolibrary.org/obo/CL_0000542) EquivalentTo [leukocyte](http://purl.obolibrary.org/obo/CL_0000738) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [neutrophillic cytoplasm](http://purl.obolibrary.org/obo/CL_0017500)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [obsolete increased nucleus size](http://purl.obolibrary.org/obo/CL_0017505)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [heterochromatin](http://purl.obolibrary.org/obo/GO_0000792)) and ([bearer of](http://purl.obolibrary.org/obo/RO_0000053) some [mononucleate](http://purl.obolibrary.org/obo/PATO_0001407)) + +- [lymphocyte](http://purl.obolibrary.org/obo/CL_0000542) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [obsolete increased nucleus size](http://purl.obolibrary.org/obo/CL_0017505) + +#### Added +- [lymphocyte](http://purl.obolibrary.org/obo/CL_0000542) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + +- [lymphocyte](http://purl.obolibrary.org/obo/CL_0000542) EquivalentTo [leukocyte](http://purl.obolibrary.org/obo/CL_0000738) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [neutrophillic cytoplasm](http://purl.obolibrary.org/obo/CL_0017500)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [heterochromatin](http://purl.obolibrary.org/obo/GO_0000792)) and ([bearer of](http://purl.obolibrary.org/obo/RO_0000053) some [mononucleate](http://purl.obolibrary.org/obo/PATO_0001407)) and ([bearer of](http://purl.obolibrary.org/obo/RO_0000053) some [high nuclear/cytoplasmic ratio](http://purl.obolibrary.org/obo/PATO_0040072)) + +- [lymphocyte](http://purl.obolibrary.org/obo/CL_0000542) SubClassOf [bearer of](http://purl.obolibrary.org/obo/RO_0000053) some [high nuclear/cytoplasmic ratio](http://purl.obolibrary.org/obo/PATO_0040072) + + +### lymphoid follicle `http://purl.obolibrary.org/obo/UBERON_0000444` +#### Removed +- [lymphoid follicle](http://purl.obolibrary.org/obo/UBERON_0000444) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "https://github.com/obophenotype/uberon/issues/7" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "https://github.com/obophenotype/uberon/issues/6" + +#### Added +- [lymphoid follicle](http://purl.obolibrary.org/obo/UBERON_0000444) [see also](http://www.w3.org/2000/01/rdf-schema#seeAlso) "https://github.com/obophenotype/uberon/issues/6"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + +- [lymphoid follicle](http://purl.obolibrary.org/obo/UBERON_0000444) [see also](http://www.w3.org/2000/01/rdf-schema#seeAlso) "https://github.com/obophenotype/uberon/issues/7"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + + +### lymphoid lineage restricted progenitor cell `http://purl.obolibrary.org/obo/CL_0000838` + +#### Added +- [lymphoid lineage restricted progenitor cell](http://purl.obolibrary.org/obo/CL_0000838) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### lymphoid system `http://purl.obolibrary.org/obo/UBERON_0002465` +#### Removed +- [lymphoid system](http://purl.obolibrary.org/obo/UBERON_0002465) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "systema lymphoideum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Lymphoid_system" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [lymphoid system](http://purl.obolibrary.org/obo/UBERON_0002465) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "systema lymphoideum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Lymphoid_system" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### macroglial cell `http://purl.obolibrary.org/obo/CL_0000126` + +#### Added +- [macroglial cell](http://purl.obolibrary.org/obo/CL_0000126) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### macromolecule metabolic process `http://purl.obolibrary.org/obo/GO_0043170` + +#### Added +- [macromolecule metabolic process](http://purl.obolibrary.org/obo/GO_0043170) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) "https://github.com/geneontology/go-ontology/issues/26424"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + +- [macromolecule metabolic process](http://purl.obolibrary.org/obo/GO_0043170) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [gocheck_do_not_annotate](http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate) + + +### macrophage `http://purl.obolibrary.org/obo/CL_0000235` + +#### Added +- [macrophage](http://purl.obolibrary.org/obo/CL_0000235) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### macrophage dendritic cell progenitor `http://purl.obolibrary.org/obo/CL_0002009` + +#### Added +- [macrophage dendritic cell progenitor](http://purl.obolibrary.org/obo/CL_0002009) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### macula `http://purl.obolibrary.org/obo/UBERON_0000054` +#### Removed +- [macula](http://purl.obolibrary.org/obo/UBERON_0000054) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [human_reference_atlas](http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas) + +- [macula](http://purl.obolibrary.org/obo/UBERON_0000054) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606) + + + +### macula densa epithelial cell `http://purl.obolibrary.org/obo/CL_1000850` + +#### Added +- [macula densa epithelial cell](http://purl.obolibrary.org/obo/CL_1000850) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### macula of saccule of membranous labyrinth `http://purl.obolibrary.org/obo/UBERON_0002212` +#### Removed +- [macula of saccule of membranous labyrinth](http://purl.obolibrary.org/obo/UBERON_0002212) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "macula sacculi" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:74944" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [macula of saccule of membranous labyrinth](http://purl.obolibrary.org/obo/UBERON_0002212) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "macula sacculi" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Macula_of_saccule" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [macula of saccule of membranous labyrinth](http://purl.obolibrary.org/obo/UBERON_0002212) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "macula sacculi" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:74944" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [macula of saccule of membranous labyrinth](http://purl.obolibrary.org/obo/UBERON_0002212) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "macula sacculi" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Macula_of_saccule" + + +### macula of utricle of membranous labyrinth `http://purl.obolibrary.org/obo/UBERON_0002214` +#### Removed +- [macula of utricle of membranous labyrinth](http://purl.obolibrary.org/obo/UBERON_0002214) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "macula utriculi" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:74960" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [macula of utricle of membranous labyrinth](http://purl.obolibrary.org/obo/UBERON_0002214) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "macula utriculi" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Macula_of_utricle" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [macula of utricle of membranous labyrinth](http://purl.obolibrary.org/obo/UBERON_0002214) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "macula utriculi" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:74960" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [macula of utricle of membranous labyrinth](http://purl.obolibrary.org/obo/UBERON_0002214) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "macula utriculi" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Macula_of_utricle" + + +### magnocellular layer of dorsal nucleus of lateral geniculate body `http://purl.obolibrary.org/obo/UBERON_0013606` +#### Removed +- [magnocellular layer of dorsal nucleus of lateral geniculate body](http://purl.obolibrary.org/obo/UBERON_0013606) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "strata magnocellularia nuclei dorsalis corporis geniculati lateralis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:76989" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [magnocellular layer of dorsal nucleus of lateral geniculate body](http://purl.obolibrary.org/obo/UBERON_0013606) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "strata magnocellularia nuclei dorsalis corporis geniculati lateralis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:76989" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### male accessory sex gland `http://purl.obolibrary.org/obo/UBERON_0010147` + +#### Added +- [male accessory sex gland](http://purl.obolibrary.org/obo/UBERON_0010147) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606) + +- [male accessory sex gland](http://purl.obolibrary.org/obo/UBERON_0010147) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [human_reference_atlas](http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas) + + +### male germ cell `http://purl.obolibrary.org/obo/CL_0000015` + +#### Added +- [male germ cell](http://purl.obolibrary.org/obo/CL_0000015) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### male organism `http://purl.obolibrary.org/obo/UBERON_0003101` +#### Removed +- [male organism](http://purl.obolibrary.org/obo/UBERON_0003101) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007004" + +#### Added +- [male organism](http://purl.obolibrary.org/obo/UBERON_0003101) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007004" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### male reproductive system `http://purl.obolibrary.org/obo/UBERON_0000079` +#### Removed +- [male reproductive system](http://purl.obolibrary.org/obo/UBERON_0000079) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00004927" + +#### Added +- [male reproductive system](http://purl.obolibrary.org/obo/UBERON_0000079) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [human_reference_atlas](http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas) + +- [male reproductive system](http://purl.obolibrary.org/obo/UBERON_0000079) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00004927" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + +- [male reproductive system](http://purl.obolibrary.org/obo/UBERON_0000079) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606) + + +### male urethral gland `http://purl.obolibrary.org/obo/UBERON_0010186` +#### Removed +- [male urethral gland](http://purl.obolibrary.org/obo/UBERON_0010186) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "glandulae urethrales urethrae masculinae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Urethral_gland" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [male urethral gland](http://purl.obolibrary.org/obo/UBERON_0010186) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "glandulae urethrales urethrae masculinae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Urethral_gland" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### male urethral meatus `http://purl.obolibrary.org/obo/UBERON_0012241` +#### Removed +- [male urethral meatus](http://purl.obolibrary.org/obo/UBERON_0012241) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ostium urethrae externum (urethra masculina)" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [male urethral meatus](http://purl.obolibrary.org/obo/UBERON_0012241) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ostium urethrae externum (urethra masculina)" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### malignant cell `http://purl.obolibrary.org/obo/CL_0001064` + +#### Added +- [malignant cell](http://purl.obolibrary.org/obo/CL_0001064) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### mammary duct `http://purl.obolibrary.org/obo/UBERON_0001765` +#### Removed +- [mammary duct](http://purl.obolibrary.org/obo/UBERON_0001765) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ductus lactiferi" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0002845" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Lactiferous_duct" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [mammary duct](http://purl.obolibrary.org/obo/UBERON_0001765) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ductus lactiferi" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0002845" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Lactiferous_duct" + + +### mammary gland `http://purl.obolibrary.org/obo/UBERON_0001911` +#### Removed +- [mammary gland](http://purl.obolibrary.org/obo/UBERON_0001911) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "glandula mammaria" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Mammary_gland" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [mammary gland](http://purl.obolibrary.org/obo/UBERON_0001911) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "glandula mammaria" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:57983" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [mammary gland](http://purl.obolibrary.org/obo/UBERON_0001911) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "glandula mammaria" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:57983" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [mammary gland](http://purl.obolibrary.org/obo/UBERON_0001911) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "glandula mammaria" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Mammary_gland" + + +### mammary gland epithelial cell `http://purl.obolibrary.org/obo/CL_0002327` + +#### Added +- [mammary gland epithelial cell](http://purl.obolibrary.org/obo/CL_0002327) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### mammillary body `http://purl.obolibrary.org/obo/UBERON_0002206` +#### Removed +- [mammillary body](http://purl.obolibrary.org/obo/UBERON_0002206) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "corpus mammillare" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:412" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [mammillary body](http://purl.obolibrary.org/obo/UBERON_0002206) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "corpora mamillaria" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:412" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [mammillary body](http://purl.obolibrary.org/obo/UBERON_0002206) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "corpus mamillaris" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:412" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [mammillary body](http://purl.obolibrary.org/obo/UBERON_0002206) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "corpus mamillare" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Mammillary_body" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [mammillary body](http://purl.obolibrary.org/obo/UBERON_0002206) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "corpora mammillaria" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:412" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [mammillary body](http://purl.obolibrary.org/obo/UBERON_0002206) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "corpus mammillare" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:412" + +- [mammillary body](http://purl.obolibrary.org/obo/UBERON_0002206) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "corpus mamillare" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Mammillary_body" + +- [mammillary body](http://purl.obolibrary.org/obo/UBERON_0002206) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "corpora mamillaria" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:412" + +- [mammillary body](http://purl.obolibrary.org/obo/UBERON_0002206) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "corpora mammillaria" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:412" + +- [mammillary body](http://purl.obolibrary.org/obo/UBERON_0002206) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "corpus mamillaris" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:412" + + +### mandibular nerve `http://purl.obolibrary.org/obo/UBERON_0000375` +#### Removed +- [mandibular nerve](http://purl.obolibrary.org/obo/UBERON_0000375) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nervus mandibularis [v3]" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:52996" + +- [mandibular nerve](http://purl.obolibrary.org/obo/UBERON_0000375) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nervus mandibularis [vc]" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:52996" + +- [mandibular nerve](http://purl.obolibrary.org/obo/UBERON_0000375) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "n. mandibularis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Mandibular_nerve" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [mandibular nerve](http://purl.obolibrary.org/obo/UBERON_0000375) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "n. mandibularis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Mandibular_nerve" + +- [mandibular nerve](http://purl.obolibrary.org/obo/UBERON_0000375) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nervus mandibularis [v3]" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:52996" + +- [mandibular nerve](http://purl.obolibrary.org/obo/UBERON_0000375) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nervus mandibularis [vc]" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:52996" + + +### mandibular prominence `http://purl.obolibrary.org/obo/UBERON_0005867` +#### Removed +- [mandibular prominence](http://purl.obolibrary.org/obo/UBERON_0005867) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "prominentia mandibularis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Mandibular_prominence" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [mandibular prominence](http://purl.obolibrary.org/obo/UBERON_0005867) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "prominentia mandibularis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Mandibular_prominence" + + +### mandibular symphysis `http://purl.obolibrary.org/obo/UBERON_0006606` +#### Removed +- [mandibular symphysis](http://purl.obolibrary.org/obo/UBERON_0006606) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "symphysis mandibulae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Symphysis_menti" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [mandibular symphysis](http://purl.obolibrary.org/obo/UBERON_0006606) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "symphysis mandibulae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Symphysis_menti" + + +### manus joint `http://purl.obolibrary.org/obo/UBERON_0001489` +#### Removed +- [manus joint](http://purl.obolibrary.org/obo/UBERON_0001489) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "articulationes manus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:71345" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [manus joint](http://purl.obolibrary.org/obo/UBERON_0001489) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "articulationes manus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:71345" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### mapping_justification `https://w3id.org/sssom/mapping_justification` + +#### Added +- AnnotationProperty: [mapping_justification](https://w3id.org/sssom/mapping_justification) + + +### mapping_provider `https://w3id.org/sssom/mapping_provider` + +#### Added +- AnnotationProperty: [mapping_provider](https://w3id.org/sssom/mapping_provider) + + +### mast cell `http://purl.obolibrary.org/obo/CL_0000097` + +#### Added +- [mast cell](http://purl.obolibrary.org/obo/CL_0000097) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### material anatomical entity `http://purl.obolibrary.org/obo/UBERON_0000465` +#### Removed +- [material anatomical entity](http://purl.obolibrary.org/obo/UBERON_0000465) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007016" + +#### Added +- [material anatomical entity](http://purl.obolibrary.org/obo/UBERON_0000465) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007016" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### mature B cell `http://purl.obolibrary.org/obo/CL_0000785` + +#### Added +- [mature B cell](http://purl.obolibrary.org/obo/CL_0000785) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### mature NK T cell `http://purl.obolibrary.org/obo/CL_0000814` + +#### Added +- [mature NK T cell](http://purl.obolibrary.org/obo/CL_0000814) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### mature T cell `http://purl.obolibrary.org/obo/CL_0002419` + +#### Added +- [mature T cell](http://purl.obolibrary.org/obo/CL_0002419) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### mature alpha-beta T cell `http://purl.obolibrary.org/obo/CL_0000791` + +#### Added +- [mature alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000791) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### mature astrocyte `http://purl.obolibrary.org/obo/CL_0002627` + +#### Added +- [mature astrocyte](http://purl.obolibrary.org/obo/CL_0002627) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### mature conventional dendritic cell `http://purl.obolibrary.org/obo/CL_0000841` + +#### Added +- [mature conventional dendritic cell](http://purl.obolibrary.org/obo/CL_0000841) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### mature gamma-delta T cell `http://purl.obolibrary.org/obo/CL_0000800` + +#### Added +- [mature gamma-delta T cell](http://purl.obolibrary.org/obo/CL_0000800) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### mature microglial cell `http://purl.obolibrary.org/obo/CL_0002629` + +#### Added +- [mature microglial cell](http://purl.obolibrary.org/obo/CL_0002629) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### maxillary artery `http://purl.obolibrary.org/obo/UBERON_0001616` +#### Removed +- [maxillary artery](http://purl.obolibrary.org/obo/UBERON_0001616) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria maxillaris" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Maxillary_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [maxillary artery](http://purl.obolibrary.org/obo/UBERON_0001616) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria maxillaris" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Maxillary_artery" + + +### maxillary nerve `http://purl.obolibrary.org/obo/UBERON_0000377` +#### Removed +- [maxillary nerve](http://purl.obolibrary.org/obo/UBERON_0000377) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nervus maxillaris [v2]" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:52724" + +- [maxillary nerve](http://purl.obolibrary.org/obo/UBERON_0000377) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nervus maxillaris [vb]" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:52724" + +- [maxillary nerve](http://purl.obolibrary.org/obo/UBERON_0000377) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "n. maxillaris" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Maxillary_nerve" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [maxillary nerve](http://purl.obolibrary.org/obo/UBERON_0000377) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nervus maxillaris [vb]" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:52724" + +- [maxillary nerve](http://purl.obolibrary.org/obo/UBERON_0000377) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nervus maxillaris [v2]" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:52724" + +- [maxillary nerve](http://purl.obolibrary.org/obo/UBERON_0000377) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "n. maxillaris" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Maxillary_nerve" + + +### maxillary prominence `http://purl.obolibrary.org/obo/UBERON_0005868` +#### Removed +- [maxillary prominence](http://purl.obolibrary.org/obo/UBERON_0005868) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "prominentia maxilaris" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Maxillary_prominence" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [maxillary prominence](http://purl.obolibrary.org/obo/UBERON_0005868) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "prominentia maxilaris" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Maxillary_prominence" + + +### medial border of scapula `http://purl.obolibrary.org/obo/UBERON_0007174` +#### Removed +- [medial border of scapula](http://purl.obolibrary.org/obo/UBERON_0007174) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "margo medialis scapulae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:23242" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [medial border of scapula](http://purl.obolibrary.org/obo/UBERON_0007174) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "margo medialis scapulae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:23242" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### medial circumflex femoral artery `http://purl.obolibrary.org/obo/UBERON_0001356` +#### Removed +- [medial circumflex femoral artery](http://purl.obolibrary.org/obo/UBERON_0001356) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria circumflexa femoris medialis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Medial_circumflex_femoral_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [medial circumflex femoral artery](http://purl.obolibrary.org/obo/UBERON_0001356) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria circumflexa femoris medialis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Medial_circumflex_femoral_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### medial ganglionic eminence `http://purl.obolibrary.org/obo/UBERON_0004024` + +#### Added +- [medial ganglionic eminence](http://purl.obolibrary.org/obo/UBERON_0004024) DisjointWith [lateral ganglionic eminence](http://purl.obolibrary.org/obo/UBERON_0004025) + - [source](http://www.geneontology.org/formats/oboInOwl#source) "lexical" + + +### medial ligament of ankle joint `http://purl.obolibrary.org/obo/UBERON_0011972` +#### Removed +- [medial ligament of ankle joint](http://purl.obolibrary.org/obo/UBERON_0011972) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ligamentum collaterale mediale articulationis talocruralis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:44055" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [medial ligament of ankle joint](http://purl.obolibrary.org/obo/UBERON_0011972) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ligamentum collaterale mediale articulationis talocruralis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:44055" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### medial marginal vein `http://purl.obolibrary.org/obo/UBERON_0001550` +#### Removed +- [medial marginal vein](http://purl.obolibrary.org/obo/UBERON_0001550) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "vena marginalis medialis pedis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:44420" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [medial marginal vein](http://purl.obolibrary.org/obo/UBERON_0001550) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "vena marginalis medialis pedis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:44420" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### medial nasal prominence `http://purl.obolibrary.org/obo/UBERON_0004068` +#### Removed +- [medial nasal prominence](http://purl.obolibrary.org/obo/UBERON_0004068) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "prominentia nasalis medialis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Medial_nasal_prominence" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [medial nasal prominence](http://purl.obolibrary.org/obo/UBERON_0004068) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "prominentia nasalis medialis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Medial_nasal_prominence" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### medial zone of hypothalamus `http://purl.obolibrary.org/obo/UBERON_0002272` +#### Removed +- [medial zone of hypothalamus](http://purl.obolibrary.org/obo/UBERON_0002272) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "zona medialis hypothalamicae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:77683" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [medial zone of hypothalamus](http://purl.obolibrary.org/obo/UBERON_0002272) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "zona medialis hypothalamicae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:77683" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### median preoptic nucleus `http://purl.obolibrary.org/obo/UBERON_0002625` +#### Removed +- [median preoptic nucleus](http://purl.obolibrary.org/obo/UBERON_0002625) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus praeopticus medianus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:378" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [median preoptic nucleus](http://purl.obolibrary.org/obo/UBERON_0002625) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus preopticus medianus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:378" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [median preoptic nucleus](http://purl.obolibrary.org/obo/UBERON_0002625) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0006168" + - [contributor](http://purl.org/dc/terms/contributor) "https://orcid.org/0000-0003-4423-4370" + +#### Added +- [median preoptic nucleus](http://purl.obolibrary.org/obo/UBERON_0002625) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0006168" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + - [author_id](https://w3id.org/sssom/author_id) [0000-0003-4423-4370](https://orcid.org/0000-0003-4423-4370) + +- [median preoptic nucleus](http://purl.obolibrary.org/obo/UBERON_0002625) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus preopticus medianus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:378" + +- [median preoptic nucleus](http://purl.obolibrary.org/obo/UBERON_0002625) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus praeopticus medianus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:378" + + +### mediastinal pleura `http://purl.obolibrary.org/obo/UBERON_0035431` +#### Removed +- [mediastinal pleura](http://purl.obolibrary.org/obo/UBERON_0035431) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pars mediastinalis pleurae parietalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:9736" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [mediastinal pleura](http://purl.obolibrary.org/obo/UBERON_0035431) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pars mediastinalis pleurae parietalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:9736" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### medium spiny neuron `http://purl.obolibrary.org/obo/CL_1001474` + +#### Added +- [medium spiny neuron](http://purl.obolibrary.org/obo/CL_1001474) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### medulla oblongata `http://purl.obolibrary.org/obo/UBERON_0001896` +#### Removed +- [medulla oblongata](http://purl.obolibrary.org/obo/UBERON_0001896) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "bulbus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:62004" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [medulla oblongata](http://purl.obolibrary.org/obo/UBERON_0001896) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "medulla oblonzata" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Medulla_oblongata" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [medulla oblongata](http://purl.obolibrary.org/obo/UBERON_0001896) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "medulla oblonzata" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Medulla_oblongata" + +- [medulla oblongata](http://purl.obolibrary.org/obo/UBERON_0001896) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "bulbus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:62004" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### medulla of lymph node `http://purl.obolibrary.org/obo/UBERON_0002007` +#### Removed +- [medulla of lymph node](http://purl.obolibrary.org/obo/UBERON_0002007) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "medulla nodi lymphoidei" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Medulla_of_lymph_node" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [medulla of lymph node](http://purl.obolibrary.org/obo/UBERON_0002007) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "medulla nodi lymphoidei" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Medulla_of_lymph_node" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### medullary thymic epithelial cell `http://purl.obolibrary.org/obo/CL_0002365` + +#### Added +- [medullary thymic epithelial cell](http://purl.obolibrary.org/obo/CL_0002365) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### megakaryocyte `http://purl.obolibrary.org/obo/CL_0000556` + +#### Added +- [megakaryocyte](http://purl.obolibrary.org/obo/CL_0000556) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### megakaryocyte progenitor cell `http://purl.obolibrary.org/obo/CL_0000553` + +#### Added +- [megakaryocyte progenitor cell](http://purl.obolibrary.org/obo/CL_0000553) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### megakaryocyte-erythroid progenitor cell `http://purl.obolibrary.org/obo/CL_0000050` + +#### Added +- [megakaryocyte-erythroid progenitor cell](http://purl.obolibrary.org/obo/CL_0000050) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### meis2 expressing cortical GABAergic cell `http://purl.obolibrary.org/obo/CL_4023065` + +#### Added +- [meis2 expressing cortical GABAergic cell](http://purl.obolibrary.org/obo/CL_4023065) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### melanocyte `http://purl.obolibrary.org/obo/CL_0000148` + +#### Added +- [melanocyte](http://purl.obolibrary.org/obo/CL_0000148) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### melanocyte of skin `http://purl.obolibrary.org/obo/CL_1000458` + +#### Added +- [melanocyte of skin](http://purl.obolibrary.org/obo/CL_1000458) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### membrane organization `http://purl.obolibrary.org/obo/GO_0061024` +#### Removed +- [membrane organization](http://purl.obolibrary.org/obo/GO_0061024) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [prokaryote_subset](http://purl.obolibrary.org/obo/go#prokaryote_subset) + +#### Added +- [membrane organization](http://purl.obolibrary.org/obo/GO_0061024) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_prokaryote](http://purl.obolibrary.org/obo/go#goslim_prokaryote) + + +### membranous labyrinth `http://purl.obolibrary.org/obo/UBERON_0001849` +#### Removed +- [membranous labyrinth](http://purl.obolibrary.org/obo/UBERON_0001849) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "labyrinthus membranaceus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Membranous_labyrinth" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [membranous labyrinth](http://purl.obolibrary.org/obo/UBERON_0001849) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "labyrinthus membranaceus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Membranous_labyrinth" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### memory B cell `http://purl.obolibrary.org/obo/CL_0000787` + +#### Added +- [memory B cell](http://purl.obolibrary.org/obo/CL_0000787) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### memory T cell `http://purl.obolibrary.org/obo/CL_0000813` + +#### Added +- [memory T cell](http://purl.obolibrary.org/obo/CL_0000813) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### memory regulatory T cell `http://purl.obolibrary.org/obo/CL_0002678` + +#### Added +- [memory regulatory T cell](http://purl.obolibrary.org/obo/CL_0002678) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### mesangial cell `http://purl.obolibrary.org/obo/CL_0000650` + +#### Added +- [mesangial cell](http://purl.obolibrary.org/obo/CL_0000650) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### mesenchymal cell `http://purl.obolibrary.org/obo/CL_0008019` + +#### Added +- [mesenchymal cell](http://purl.obolibrary.org/obo/CL_0008019) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### mesenchymal lymphangioblast `http://purl.obolibrary.org/obo/CL_0005021` + +#### Added +- [mesenchymal lymphangioblast](http://purl.obolibrary.org/obo/CL_0005021) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### mesenchymal stem cell `http://purl.obolibrary.org/obo/CL_0000134` + +#### Added +- [mesenchymal stem cell](http://purl.obolibrary.org/obo/CL_0000134) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### mesenchymal stem cell of adipose tissue `http://purl.obolibrary.org/obo/CL_0002570` + +#### Added +- [mesenchymal stem cell of adipose tissue](http://purl.obolibrary.org/obo/CL_0002570) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### mesenchyme `http://purl.obolibrary.org/obo/UBERON_0003104` +#### Removed +- [mesenchyme](http://purl.obolibrary.org/obo/UBERON_0003104) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "mesenchyma" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Mesenchyme" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [mesenchyme](http://purl.obolibrary.org/obo/UBERON_0003104) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "mesenchyma" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Mesenchyme" + + +### mesenteric lymph node `http://purl.obolibrary.org/obo/UBERON_0002509` +#### Removed +- [mesenteric lymph node](http://purl.obolibrary.org/obo/UBERON_0002509) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nodi lymphoidei mesenterici" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0000767" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [mesenteric lymph node](http://purl.obolibrary.org/obo/UBERON_0002509) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nodi lymphoidei mesenterici" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0000767" + + +### mesoderm `http://purl.obolibrary.org/obo/UBERON_0000926` +#### Removed +- [mesoderm](http://purl.obolibrary.org/obo/UBERON_0000926) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00000126" + +#### Added +- [mesoderm](http://purl.obolibrary.org/obo/UBERON_0000926) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00000126" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### mesodermal cell `http://purl.obolibrary.org/obo/CL_0000222` + +#### Added +- [mesodermal cell](http://purl.obolibrary.org/obo/CL_0000222) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### mesonephric duct `http://purl.obolibrary.org/obo/UBERON_0003074` +#### Removed +- [mesonephric duct](http://purl.obolibrary.org/obo/UBERON_0003074) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ductus mesonephricus; ductus Wolffi" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Mesonephric_duct" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [mesonephric duct](http://purl.obolibrary.org/obo/UBERON_0003074) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0005990" + - [contributor](http://purl.org/dc/terms/contributor) "https://orcid.org/0000-0003-4423-4370" + +#### Added +- [mesonephric duct](http://purl.obolibrary.org/obo/UBERON_0003074) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ductus mesonephricus; ductus Wolffi" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Mesonephric_duct" + +- [mesonephric duct](http://purl.obolibrary.org/obo/UBERON_0003074) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0005990" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + - [author_id](https://w3id.org/sssom/author_id) [0000-0003-4423-4370](https://orcid.org/0000-0003-4423-4370) + + +### mesonephric glomerular capillary `http://purl.obolibrary.org/obo/UBERON_0006183` +#### Removed +- [mesonephric glomerular capillary](http://purl.obolibrary.org/obo/UBERON_0006183) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GO:0061249" + +#### Added +- [mesonephric glomerular capillary](http://purl.obolibrary.org/obo/UBERON_0006183) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Missing definition for term UBERON:0006183. Please replace it using linked reference." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GO:0061249" + + +### mesonephric smooth muscle tissue `http://purl.obolibrary.org/obo/UBERON_0005321` +#### Removed +- [mesonephric smooth muscle tissue](http://purl.obolibrary.org/obo/UBERON_0005321) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GO:0061214" + +#### Added +- [mesonephric smooth muscle tissue](http://purl.obolibrary.org/obo/UBERON_0005321) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Missing definition for term UBERON:0005321. Please replace it using linked reference." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GO:0061214" + + +### mesonephric tubule `http://purl.obolibrary.org/obo/UBERON_0000083` +#### Removed +- [mesonephric tubule](http://purl.obolibrary.org/obo/UBERON_0000083) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tubuli mesonephrici" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Mesonephric_tubules" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [mesonephric tubule](http://purl.obolibrary.org/obo/UBERON_0000083) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tubuli mesonephrici" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Mesonephric_tubules" + + +### mesothelial cell `http://purl.obolibrary.org/obo/CL_0000077` + +#### Added +- [mesothelial cell](http://purl.obolibrary.org/obo/CL_0000077) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### mesothelial cell of epicardium `http://purl.obolibrary.org/obo/CL_0011019` + +#### Added +- [mesothelial cell of epicardium](http://purl.obolibrary.org/obo/CL_0011019) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### mesothelial cell of pleura `http://purl.obolibrary.org/obo/CL_1000491` + +#### Added +- [mesothelial cell of pleura](http://purl.obolibrary.org/obo/CL_1000491) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### mesothelial cell of visceral pleura `http://purl.obolibrary.org/obo/CL_1000493` + +#### Added +- [mesothelial cell of visceral pleura](http://purl.obolibrary.org/obo/CL_1000493) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### mesothelial fibroblast `http://purl.obolibrary.org/obo/CL_4023054` + +#### Added +- [mesothelial fibroblast](http://purl.obolibrary.org/obo/CL_4023054) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### metacarpophalangeal joint `http://purl.obolibrary.org/obo/UBERON_0003695` +#### Removed +- [metacarpophalangeal joint](http://purl.obolibrary.org/obo/UBERON_0003695) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "articulationes metacarpophalangeae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Metacarpophalangeal_joint" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [metacarpophalangeal joint](http://purl.obolibrary.org/obo/UBERON_0003695) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "articulationes metacarpophalangeae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Metacarpophalangeal_joint" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### metacarpus skeleton `http://purl.obolibrary.org/obo/UBERON_0010544` +#### Removed +- [metacarpus skeleton](http://purl.obolibrary.org/obo/UBERON_0010544) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ossa metacarpi [I-V]" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:71336" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [metacarpus skeleton](http://purl.obolibrary.org/obo/UBERON_0010544) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "metacarpalia" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Metacarpus" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [metacarpus skeleton](http://purl.obolibrary.org/obo/UBERON_0010544) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ossa metacarpalia [I-V]" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:71336" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [metacarpus skeleton](http://purl.obolibrary.org/obo/UBERON_0010544) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ossa metacarpi [I-V]" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:71336" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [metacarpus skeleton](http://purl.obolibrary.org/obo/UBERON_0010544) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ossa metacarpalia [I-V]" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:71336" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [metacarpus skeleton](http://purl.obolibrary.org/obo/UBERON_0010544) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "metacarpalia" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Metacarpus" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### metanephros induced blastemal cells `http://purl.obolibrary.org/obo/UBERON_0010531` +#### Removed +- [metanephros induced blastemal cells](http://purl.obolibrary.org/obo/UBERON_0010531) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "http://www.embryology.ch/anglais/turinary/urinhaute03.html" + + + +### metatarsophalangeal joint `http://purl.obolibrary.org/obo/UBERON_0003696` +#### Removed +- [metatarsophalangeal joint](http://purl.obolibrary.org/obo/UBERON_0003696) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "articulationes metatarsophalangeae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Metatarsophalangeal_articulations" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [metatarsophalangeal joint](http://purl.obolibrary.org/obo/UBERON_0003696) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "articulationes metatarsophalangeae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Metatarsophalangeal_articulations" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### metatarsus region `http://purl.obolibrary.org/obo/UBERON_0000983` +#### Removed +- [metatarsus region](http://purl.obolibrary.org/obo/UBERON_0000983) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regio metatarsalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:24997" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [metatarsus region](http://purl.obolibrary.org/obo/UBERON_0000983) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regio metatarsalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:24997" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### metatarsus skeleton `http://purl.obolibrary.org/obo/UBERON_0010545` +#### Removed +- [metatarsus skeleton](http://purl.obolibrary.org/obo/UBERON_0010545) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ossa metatarsalia" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Metatarsus" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [metatarsus skeleton](http://purl.obolibrary.org/obo/UBERON_0010545) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ossa metatarsalia [I-V]" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:71340" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [metatarsus skeleton](http://purl.obolibrary.org/obo/UBERON_0010545) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ossa metatarsi[I-V]" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:71340" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [metatarsus skeleton](http://purl.obolibrary.org/obo/UBERON_0010545) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ossa metatarsi[I-V]" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:71340" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [metatarsus skeleton](http://purl.obolibrary.org/obo/UBERON_0010545) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ossa metatarsalia" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Metatarsus" + +- [metatarsus skeleton](http://purl.obolibrary.org/obo/UBERON_0010545) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ossa metatarsalia [I-V]" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:71340" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### metathalamus `http://purl.obolibrary.org/obo/UBERON_0002704` +#### Removed +- [metathalamus](http://purl.obolibrary.org/obo/UBERON_0002704) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "corpora geniculata" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Metathalamus" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [metathalamus](http://purl.obolibrary.org/obo/UBERON_0002704) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "corpora geniculata" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Metathalamus" + +- [metathalamus](http://purl.obolibrary.org/obo/UBERON_0002704) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D005829" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [LexicalMatching](https://w3id.org/semapv/vocab/LexicalMatching) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### microfold cell of epithelium of small intestine `http://purl.obolibrary.org/obo/CL_1000353` + +#### Added +- [microfold cell of epithelium of small intestine](http://purl.obolibrary.org/obo/CL_1000353) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### microglial cell `http://purl.obolibrary.org/obo/CL_0000129` + +#### Added +- [microglial cell](http://purl.obolibrary.org/obo/CL_0000129) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### midbrain `http://purl.obolibrary.org/obo/UBERON_0001891` +#### Removed +- [midbrain](http://purl.obolibrary.org/obo/UBERON_0001891) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "mesencephalon" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Midbrain" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [midbrain](http://purl.obolibrary.org/obo/UBERON_0001891) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "mesencephalon" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Midbrain" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### midbrain tectum `http://purl.obolibrary.org/obo/UBERON_0002314` +#### Removed +- [midbrain tectum](http://purl.obolibrary.org/obo/UBERON_0002314) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "t. mesencephali" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Midbrain_tectum" + +- [midbrain tectum](http://purl.obolibrary.org/obo/UBERON_0002314) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tectum mesencephalicum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:465" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [midbrain tectum](http://purl.obolibrary.org/obo/UBERON_0002314) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "t. mesencephali" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Midbrain_tectum" + +- [midbrain tectum](http://purl.obolibrary.org/obo/UBERON_0002314) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tectum mesencephalicum" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:465" + + +### midbrain tegmentum `http://purl.obolibrary.org/obo/UBERON_0001943` +#### Removed +- [midbrain tegmentum](http://purl.obolibrary.org/obo/UBERON_0001943) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tegmentum mesencephalicum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:491" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [midbrain tegmentum](http://purl.obolibrary.org/obo/UBERON_0001943) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tegmentum mesencephali" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Midbrain_tegmentum" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [midbrain tegmentum](http://purl.obolibrary.org/obo/UBERON_0001943) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tegmentum mesencephalicum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:491" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [midbrain tegmentum](http://purl.obolibrary.org/obo/UBERON_0001943) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tegmentum mesencephali" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Midbrain_tegmentum" + +- [midbrain tegmentum](http://purl.obolibrary.org/obo/UBERON_0001943) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D013681" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [LexicalMatching](https://w3id.org/semapv/vocab/LexicalMatching) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### middle colic artery `http://purl.obolibrary.org/obo/UBERON_0001196` +#### Removed +- [middle colic artery](http://purl.obolibrary.org/obo/UBERON_0001196) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria colica media" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Middle_colic_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [middle colic artery](http://purl.obolibrary.org/obo/UBERON_0001196) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria colica media" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Middle_colic_artery" + + +### middle colic vein `http://purl.obolibrary.org/obo/UBERON_0001218` +#### Removed +- [middle colic vein](http://purl.obolibrary.org/obo/UBERON_0001218) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vena colica media" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Middle_colic_vein" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [middle colic vein](http://purl.obolibrary.org/obo/UBERON_0001218) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vena colica media" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Middle_colic_vein" + + +### middle ear `http://purl.obolibrary.org/obo/UBERON_0001756` +#### Removed +- [middle ear](http://purl.obolibrary.org/obo/UBERON_0001756) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "auris media" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0002099" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Middle_ear" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [middle ear](http://purl.obolibrary.org/obo/UBERON_0001756) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "auris media" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0002099" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Middle_ear" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### middle phalanx of manus `http://purl.obolibrary.org/obo/UBERON_0003864` +#### Removed +- [middle phalanx of manus](http://purl.obolibrary.org/obo/UBERON_0003864) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "phalanx media manus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:75817" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [middle phalanx of manus](http://purl.obolibrary.org/obo/UBERON_0003864) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "phalanx media manus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:75817" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### middle phalanx of pes `http://purl.obolibrary.org/obo/UBERON_0003866` +#### Removed +- [middle phalanx of pes](http://purl.obolibrary.org/obo/UBERON_0003866) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "phalanx media pedis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:75829" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [middle phalanx of pes](http://purl.obolibrary.org/obo/UBERON_0003866) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "phalanx media pedis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:75829" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### midgut `http://purl.obolibrary.org/obo/UBERON_0001045` +#### Removed +- [midgut](http://purl.obolibrary.org/obo/UBERON_0001045) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005383" + +- [midgut](http://purl.obolibrary.org/obo/UBERON_0001045) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "mesenteron" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Midgut" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [midgut](http://purl.obolibrary.org/obo/UBERON_0001045) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005383" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + +- [midgut](http://purl.obolibrary.org/obo/UBERON_0001045) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "mesenteron" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Midgut" + + +### midzonal region hepatocyte `http://purl.obolibrary.org/obo/CL_0019028` + +#### Added +- [midzonal region hepatocyte](http://purl.obolibrary.org/obo/CL_0019028) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### migratory enteric neural crest cell `http://purl.obolibrary.org/obo/CL_0002607` + +#### Added +- [migratory enteric neural crest cell](http://purl.obolibrary.org/obo/CL_0002607) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### molecular adaptor activity `http://purl.obolibrary.org/obo/GO_0060090` +#### Removed +- [molecular adaptor activity](http://purl.obolibrary.org/obo/GO_0060090) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [prokaryote_subset](http://purl.obolibrary.org/obo/go#prokaryote_subset) + +#### Added +- [molecular adaptor activity](http://purl.obolibrary.org/obo/GO_0060090) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_prokaryote](http://purl.obolibrary.org/obo/go#goslim_prokaryote) + + +### molecular layer of cerebellar cortex `http://purl.obolibrary.org/obo/UBERON_0002974` +#### Removed +- [molecular layer of cerebellar cortex](http://purl.obolibrary.org/obo/UBERON_0002974) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "stratum moleculare corticis cerebelli" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:83897" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [molecular layer of cerebellar cortex](http://purl.obolibrary.org/obo/UBERON_0002974) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "fasciculi thalami" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:366" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [molecular layer of cerebellar cortex](http://purl.obolibrary.org/obo/UBERON_0002974) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "fasciculi thalami" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:366" + +- [molecular layer of cerebellar cortex](http://purl.obolibrary.org/obo/UBERON_0002974) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "stratum moleculare corticis cerebelli" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:83897" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### molecular transducer activity `http://purl.obolibrary.org/obo/GO_0060089` +#### Removed +- [molecular transducer activity](http://purl.obolibrary.org/obo/GO_0060089) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [prokaryote_subset](http://purl.obolibrary.org/obo/go#prokaryote_subset) + +#### Added +- [molecular transducer activity](http://purl.obolibrary.org/obo/GO_0060089) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_prokaryote](http://purl.obolibrary.org/obo/go#goslim_prokaryote) + + +### monocyte `http://purl.obolibrary.org/obo/CL_0000576` + +#### Added +- [monocyte](http://purl.obolibrary.org/obo/CL_0000576) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### mononuclear cell `http://purl.obolibrary.org/obo/CL_0000842` + +#### Added +- [mononuclear cell](http://purl.obolibrary.org/obo/CL_0000842) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### mononuclear phagocyte `http://purl.obolibrary.org/obo/CL_0000113` + +#### Added +- [mononuclear phagocyte](http://purl.obolibrary.org/obo/CL_0000113) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### motor neuron `http://purl.obolibrary.org/obo/CL_0000100` + +#### Added +- [motor neuron](http://purl.obolibrary.org/obo/CL_0000100) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### mouth `http://purl.obolibrary.org/obo/UBERON_0000165` +#### Removed +- [mouth](http://purl.obolibrary.org/obo/UBERON_0000165) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cavital oralis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Mouth" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [mouth](http://purl.obolibrary.org/obo/UBERON_0000165) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regio oralis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:49184" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0004698" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [mouth](http://purl.obolibrary.org/obo/UBERON_0000165) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00003126" + +#### Added +- [mouth](http://purl.obolibrary.org/obo/UBERON_0000165) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regio oralis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:49184" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0004698" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [mouth](http://purl.obolibrary.org/obo/UBERON_0000165) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00003126" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + +- [mouth](http://purl.obolibrary.org/obo/UBERON_0000165) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cavital oralis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Mouth" + + +### mouth mucosa `http://purl.obolibrary.org/obo/UBERON_0003729` +#### Removed +- [mouth mucosa](http://purl.obolibrary.org/obo/UBERON_0003729) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tunica mucosa oris" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Oral_mucosa" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [mouth mucosa](http://purl.obolibrary.org/obo/UBERON_0003729) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica mucosa oris" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:59660" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [mouth mucosa](http://purl.obolibrary.org/obo/UBERON_0003729) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica mucosa oris" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:59660" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [mouth mucosa](http://purl.obolibrary.org/obo/UBERON_0003729) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tunica mucosa oris" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Oral_mucosa" + + +### mucosa `http://purl.obolibrary.org/obo/UBERON_0000344` +#### Removed +- [mucosa](http://purl.obolibrary.org/obo/UBERON_0000344) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tunica mucosa" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0000886" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Mucous_membrane" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [mucosa](http://purl.obolibrary.org/obo/UBERON_0000344) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tunica mucosa" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0000886" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Mucous_membrane" + + +### mucosa of deferent duct `http://purl.obolibrary.org/obo/UBERON_0004986` +#### Removed +- [mucosa of deferent duct](http://purl.obolibrary.org/obo/UBERON_0004986) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica mucosa ductus deferentis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:19240" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [mucosa of deferent duct](http://purl.obolibrary.org/obo/UBERON_0004986) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica mucosa ductus deferentis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:19240" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### mucosa of gallbladder `http://purl.obolibrary.org/obo/UBERON_0005033` +#### Removed +- [mucosa of gallbladder](http://purl.obolibrary.org/obo/UBERON_0005033) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica mucosa vesicae biliaris" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:14662" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [mucosa of gallbladder](http://purl.obolibrary.org/obo/UBERON_0005033) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica mucosa vesicae biliaris" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:14662" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### mucosa of large intestine `http://purl.obolibrary.org/obo/UBERON_0001207` +#### Removed +- [mucosa of large intestine](http://purl.obolibrary.org/obo/UBERON_0001207) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica mucosa intestini crassi" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:14969" + +#### Added +- [mucosa of large intestine](http://purl.obolibrary.org/obo/UBERON_0001207) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica mucosa intestini crassi" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:14969" + + +### mucosa of larynx `http://purl.obolibrary.org/obo/UBERON_0001824` +#### Removed +- [mucosa of larynx](http://purl.obolibrary.org/obo/UBERON_0001824) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica mucosa laryngis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:59662" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [mucosa of larynx](http://purl.obolibrary.org/obo/UBERON_0001824) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica mucosa laryngis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:59662" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### mucosa of middle ear `http://purl.obolibrary.org/obo/UBERON_0005026` +#### Removed +- [mucosa of middle ear](http://purl.obolibrary.org/obo/UBERON_0005026) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica mucosa cavitatis tympanicae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:59663" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [mucosa of middle ear](http://purl.obolibrary.org/obo/UBERON_0005026) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica mucosa cavitatis tympanicae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:59663" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### mucosa of prostatic urethra `http://purl.obolibrary.org/obo/UBERON_0005015` +#### Removed +- [mucosa of prostatic urethra](http://purl.obolibrary.org/obo/UBERON_0005015) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica mucosa urethrae prosticae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:77079" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [mucosa of prostatic urethra](http://purl.obolibrary.org/obo/UBERON_0005015) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica mucosa urethrae prosticae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:77079" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### mucosa of renal pelvis `http://purl.obolibrary.org/obo/UBERON_0005006` +#### Removed +- [mucosa of renal pelvis](http://purl.obolibrary.org/obo/UBERON_0005006) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica mucosa pelvis renalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:17931" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [mucosa of renal pelvis](http://purl.obolibrary.org/obo/UBERON_0005006) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica mucosa pelvis renalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:17931" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### mucosa of seminal vesicle `http://purl.obolibrary.org/obo/UBERON_0004984` +#### Removed +- [mucosa of seminal vesicle](http://purl.obolibrary.org/obo/UBERON_0004984) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica mucosa glandulae vesiculosae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:19405" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [mucosa of seminal vesicle](http://purl.obolibrary.org/obo/UBERON_0004984) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica mucosa glandulae vesiculosae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:19405" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### mucosa of small intestine `http://purl.obolibrary.org/obo/UBERON_0001204` +#### Removed +- [mucosa of small intestine](http://purl.obolibrary.org/obo/UBERON_0001204) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica mucosa intestini tenuis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:14933" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [mucosa of small intestine](http://purl.obolibrary.org/obo/UBERON_0001204) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica mucosa intestini tenuis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:14933" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### mucosa of stomach `http://purl.obolibrary.org/obo/UBERON_0001199` +#### Removed +- [mucosa of stomach](http://purl.obolibrary.org/obo/UBERON_0001199) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica mucosa gastricae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:14907" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [mucosa of stomach](http://purl.obolibrary.org/obo/UBERON_0001199) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tunica mucosa gastris" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0001308" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Gastric_mucosa" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [mucosa of stomach](http://purl.obolibrary.org/obo/UBERON_0001199) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica mucosa gastricae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:14907" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [mucosa of stomach](http://purl.obolibrary.org/obo/UBERON_0001199) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tunica mucosa gastris" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0001308" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Gastric_mucosa" + + +### mucosa of tongue `http://purl.obolibrary.org/obo/UBERON_0005020` +#### Removed +- [mucosa of tongue](http://purl.obolibrary.org/obo/UBERON_0005020) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica mucosa linguae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:54807" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [mucosa of tongue](http://purl.obolibrary.org/obo/UBERON_0005020) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica mucosa linguae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:54807" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### mucosa of ureter `http://purl.obolibrary.org/obo/UBERON_0004980` +#### Removed +- [mucosa of ureter](http://purl.obolibrary.org/obo/UBERON_0004980) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica mucosa ureteris" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:15894" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [mucosa of ureter](http://purl.obolibrary.org/obo/UBERON_0004980) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica mucosa ureteris" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:15894" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### mucosa of urinary bladder `http://purl.obolibrary.org/obo/UBERON_0001259` +#### Removed +- [mucosa of urinary bladder](http://purl.obolibrary.org/obo/UBERON_0001259) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica mucosa (vesica urinaria)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:15928" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [mucosa of urinary bladder](http://purl.obolibrary.org/obo/UBERON_0001259) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica mucosa vesicae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:15928" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [mucosa of urinary bladder](http://purl.obolibrary.org/obo/UBERON_0001259) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica mucosa (vesica urinaria)" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:15928" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [mucosa of urinary bladder](http://purl.obolibrary.org/obo/UBERON_0001259) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica mucosa vesicae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:15928" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### mucosa of uterine tube `http://purl.obolibrary.org/obo/UBERON_0005048` +#### Removed +- [mucosa of uterine tube](http://purl.obolibrary.org/obo/UBERON_0005048) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica mucosa tubae uterinae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:18319" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [mucosa of uterine tube](http://purl.obolibrary.org/obo/UBERON_0005048) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica mucosa tubae uterinae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:18319" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### mucosa of vagina `http://purl.obolibrary.org/obo/UBERON_0004983` +#### Removed +- [mucosa of vagina](http://purl.obolibrary.org/obo/UBERON_0004983) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica mucosa vaginae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:19975" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [mucosa of vagina](http://purl.obolibrary.org/obo/UBERON_0004983) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica mucosa vaginae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:19975" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### mucosal invariant T cell `http://purl.obolibrary.org/obo/CL_0000940` + +#### Added +- [mucosal invariant T cell](http://purl.obolibrary.org/obo/CL_0000940) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### mucous gland `http://purl.obolibrary.org/obo/UBERON_0000414` +#### Removed +- [mucous gland](http://purl.obolibrary.org/obo/UBERON_0000414) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "glandula mucosa" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Mucous_gland" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [mucous gland](http://purl.obolibrary.org/obo/UBERON_0000414) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "glandula mucosa" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Mucous_gland" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### mucous neck cell `http://purl.obolibrary.org/obo/CL_0000651` + +#### Added +- [mucous neck cell](http://purl.obolibrary.org/obo/CL_0000651) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### mucus secreting cell `http://purl.obolibrary.org/obo/CL_0000319` + +#### Added +- [mucus secreting cell](http://purl.obolibrary.org/obo/CL_0000319) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### multi cell part structure `http://purl.obolibrary.org/obo/UBERON_0005162` +#### Removed +- [multi cell part structure](http://purl.obolibrary.org/obo/UBERON_0005162) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007060" + +#### Added +- [multi cell part structure](http://purl.obolibrary.org/obo/UBERON_0005162) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007060" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### multi-ciliated epithelial cell `http://purl.obolibrary.org/obo/CL_0005012` + +#### Added +- [multi-ciliated epithelial cell](http://purl.obolibrary.org/obo/CL_0005012) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### multi-tissue structure `http://purl.obolibrary.org/obo/UBERON_0000481` +#### Removed +- [multi-tissue structure](http://purl.obolibrary.org/obo/UBERON_0000481) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007010" + +#### Added +- [multi-tissue structure](http://purl.obolibrary.org/obo/UBERON_0000481) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007010" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### multicellular anatomical structure `http://purl.obolibrary.org/obo/UBERON_0010000` +#### Removed +- [multicellular anatomical structure](http://purl.obolibrary.org/obo/UBERON_0010000) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00100313" + +#### Added +- [multicellular anatomical structure](http://purl.obolibrary.org/obo/UBERON_0010000) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00100313" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### multicellular organism `http://purl.obolibrary.org/obo/UBERON_0000468` +#### Removed +- [multicellular organism](http://purl.obolibrary.org/obo/UBERON_0000468) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00000001" + +#### Added +- [multicellular organism](http://purl.obolibrary.org/obo/UBERON_0000468) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00000001" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### mural cell `http://purl.obolibrary.org/obo/CL_0008034` + +#### Added +- [mural cell](http://purl.obolibrary.org/obo/CL_0008034) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### muscle cell `http://purl.obolibrary.org/obo/CL_0000187` + +#### Added +- [muscle cell](http://purl.obolibrary.org/obo/CL_0000187) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### muscle layer of esophagus `http://purl.obolibrary.org/obo/UBERON_0011878` +#### Removed +- [muscle layer of esophagus](http://purl.obolibrary.org/obo/UBERON_0011878) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica muscularis oesophageae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [muscle layer of esophagus](http://purl.obolibrary.org/obo/UBERON_0011878) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tela muscularis (oesophagus)" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:62998" + +- [muscle layer of esophagus](http://purl.obolibrary.org/obo/UBERON_0011878) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica muscularis esophagi" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [muscle layer of esophagus](http://purl.obolibrary.org/obo/UBERON_0011878) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica muscularis oesophageae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [muscle layer of esophagus](http://purl.obolibrary.org/obo/UBERON_0011878) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica muscularis esophagi" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [muscle layer of esophagus](http://purl.obolibrary.org/obo/UBERON_0011878) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tela muscularis (oesophagus)" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:62998" + + +### muscle layer of large intestine `http://purl.obolibrary.org/obo/UBERON_0011198` +#### Removed +- [muscle layer of large intestine](http://purl.obolibrary.org/obo/UBERON_0011198) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica muscularis intestini crassi" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [muscle layer of large intestine](http://purl.obolibrary.org/obo/UBERON_0011198) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica muscularis intestini crassi" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### muscle layer of oviduct `http://purl.obolibrary.org/obo/UBERON_0006642` +#### Removed +- [muscle layer of oviduct](http://purl.obolibrary.org/obo/UBERON_0006642) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica muscularis tubae uterinae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:18318" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [muscle layer of oviduct](http://purl.obolibrary.org/obo/UBERON_0006642) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica muscularis tubae uterinae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:18318" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### muscle layer of small intestine `http://purl.obolibrary.org/obo/UBERON_0011201` +#### Removed +- [muscle layer of small intestine](http://purl.obolibrary.org/obo/UBERON_0011201) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica muscularis intestini tenuis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [muscle layer of small intestine](http://purl.obolibrary.org/obo/UBERON_0011201) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica muscularis intestini tenuis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### muscle of iris `http://purl.obolibrary.org/obo/UBERON_0001606` +#### Removed +- [muscle of iris](http://purl.obolibrary.org/obo/UBERON_0001606) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Iris_muscle" + + + +### muscle precursor cell `http://purl.obolibrary.org/obo/CL_0000680` + +#### Added +- [muscle precursor cell](http://purl.obolibrary.org/obo/CL_0000680) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### muscular coat `http://purl.obolibrary.org/obo/UBERON_0006660` +#### Removed +- [muscular coat](http://purl.obolibrary.org/obo/UBERON_0006660) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica muscularis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0004838" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [muscular coat](http://purl.obolibrary.org/obo/UBERON_0006660) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica muscularis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0004838" + + +### muscular coat of seminal vesicle `http://purl.obolibrary.org/obo/UBERON_0004665` +#### Removed +- [muscular coat of seminal vesicle](http://purl.obolibrary.org/obo/UBERON_0004665) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica muscularis glandulae vesiculosae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:19404" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [muscular coat of seminal vesicle](http://purl.obolibrary.org/obo/UBERON_0004665) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica muscularis glandulae vesiculosae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:19404" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### muscular coat of ureter `http://purl.obolibrary.org/obo/UBERON_0006855` +#### Removed +- [muscular coat of ureter](http://purl.obolibrary.org/obo/UBERON_0006855) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica muscularis ureteris" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [muscular coat of ureter](http://purl.obolibrary.org/obo/UBERON_0006855) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica muscularis (ureter)" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [muscular coat of ureter](http://purl.obolibrary.org/obo/UBERON_0006855) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica muscularis ureteris" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [muscular coat of ureter](http://purl.obolibrary.org/obo/UBERON_0006855) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica muscularis (ureter)" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### muscular coat of vas deferens `http://purl.obolibrary.org/obo/UBERON_0004224` +#### Removed +- [muscular coat of vas deferens](http://purl.obolibrary.org/obo/UBERON_0004224) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica muscularis ductus deferentis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:19239" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [muscular coat of vas deferens](http://purl.obolibrary.org/obo/UBERON_0004224) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica muscularis ductus deferentis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:19239" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### muscular layer of vagina `http://purl.obolibrary.org/obo/UBERON_0006652` +#### Removed +- [muscular layer of vagina](http://purl.obolibrary.org/obo/UBERON_0006652) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica muscularis vaginae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:19976" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [muscular layer of vagina](http://purl.obolibrary.org/obo/UBERON_0006652) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica muscularis vaginae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:19976" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### musculature `http://purl.obolibrary.org/obo/UBERON_0001015` +#### Removed +- [musculature](http://purl.obolibrary.org/obo/UBERON_0001015) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "musculi" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:32558" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [musculature](http://purl.obolibrary.org/obo/UBERON_0001015) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "musculi" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:32558" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### musculature of back `http://purl.obolibrary.org/obo/UBERON_0004469` +#### Removed +- [musculature of back](http://purl.obolibrary.org/obo/UBERON_0004469) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "musculi dorsi" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:71291" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [musculature of back](http://purl.obolibrary.org/obo/UBERON_0004469) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "musculi dorsi" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:71291" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### musculature of face `http://purl.obolibrary.org/obo/UBERON_0004473` +#### Removed +- [musculature of face](http://purl.obolibrary.org/obo/UBERON_0004473) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "musculi faciei" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:71288" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [musculature of face](http://purl.obolibrary.org/obo/UBERON_0004473) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "musculi faciei" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:71288" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### musculature of neck `http://purl.obolibrary.org/obo/UBERON_0004465` +#### Removed +- [musculature of neck](http://purl.obolibrary.org/obo/UBERON_0004465) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "musculi colli" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:71290" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [musculature of neck](http://purl.obolibrary.org/obo/UBERON_0004465) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "musculi cervicis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:71290" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [musculature of neck](http://purl.obolibrary.org/obo/UBERON_0004465) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "musculi colli" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:71290" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [musculature of neck](http://purl.obolibrary.org/obo/UBERON_0004465) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "musculi cervicis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:71290" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### musculature of thorax `http://purl.obolibrary.org/obo/UBERON_0004464` +#### Removed +- [musculature of thorax](http://purl.obolibrary.org/obo/UBERON_0004464) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "musculi thoracis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:71293" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [musculature of thorax](http://purl.obolibrary.org/obo/UBERON_0004464) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "musculi thoracis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:71293" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### mushroom body `http://purl.obolibrary.org/obo/UBERON_0001058` +#### Removed +- [mushroom body](http://purl.obolibrary.org/obo/UBERON_0001058) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005801" + +#### Added +- [mushroom body](http://purl.obolibrary.org/obo/UBERON_0001058) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005801" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### myelencephalon `http://purl.obolibrary.org/obo/UBERON_0005290` +#### Removed +- [myelencephalon](http://purl.obolibrary.org/obo/UBERON_0005290) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D054024" + +#### Added +- [myelencephalon](http://purl.obolibrary.org/obo/UBERON_0005290) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D054024" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [author_id](https://w3id.org/sssom/author_id) [0000-0001-9439-5346](https://orcid.org/0000-0001-9439-5346) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### myeloblast `http://purl.obolibrary.org/obo/CL_0000835` +#### Removed +- [myeloblast](http://purl.obolibrary.org/obo/CL_0000835) EquivalentTo [granulocytopoietic cell](http://purl.obolibrary.org/obo/CL_0002191) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [basophilic cytoplasm](http://purl.obolibrary.org/obo/CL_0017503)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [obsolete increased nucleus size](http://purl.obolibrary.org/obo/CL_0017505)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [euchromatin](http://purl.obolibrary.org/obo/GO_0000791)) and ([lacks_part](http://purl.obolibrary.org/obo/CL_4030045) some [azurophil granule](http://purl.obolibrary.org/obo/GO_0042582)) + +- [myeloblast](http://purl.obolibrary.org/obo/CL_0000835) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [obsolete increased nucleus size](http://purl.obolibrary.org/obo/CL_0017505) + +#### Added +- [myeloblast](http://purl.obolibrary.org/obo/CL_0000835) EquivalentTo [granulocytopoietic cell](http://purl.obolibrary.org/obo/CL_0002191) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [basophilic cytoplasm](http://purl.obolibrary.org/obo/CL_0017503)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [euchromatin](http://purl.obolibrary.org/obo/GO_0000791)) and ([lacks_part](http://purl.obolibrary.org/obo/CL_4030045) some [azurophil granule](http://purl.obolibrary.org/obo/GO_0042582)) and ([bearer of](http://purl.obolibrary.org/obo/RO_0000053) some [high nuclear/cytoplasmic ratio](http://purl.obolibrary.org/obo/PATO_0040072)) + +- [myeloblast](http://purl.obolibrary.org/obo/CL_0000835) SubClassOf [bearer of](http://purl.obolibrary.org/obo/RO_0000053) some [high nuclear/cytoplasmic ratio](http://purl.obolibrary.org/obo/PATO_0040072) + + +### myelocyte `http://purl.obolibrary.org/obo/CL_0002193` + +#### Added +- [myelocyte](http://purl.obolibrary.org/obo/CL_0002193) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### myeloid cell `http://purl.obolibrary.org/obo/CL_0000763` + +#### Added +- [myeloid cell](http://purl.obolibrary.org/obo/CL_0000763) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### myeloid dendritic cell `http://purl.obolibrary.org/obo/CL_0000782` + +#### Added +- [myeloid dendritic cell](http://purl.obolibrary.org/obo/CL_0000782) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### myeloid dendritic cell, human `http://purl.obolibrary.org/obo/CL_0001057` + +#### Added +- [myeloid dendritic cell, human](http://purl.obolibrary.org/obo/CL_0001057) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### myeloid leukocyte `http://purl.obolibrary.org/obo/CL_0000766` + +#### Added +- [myeloid leukocyte](http://purl.obolibrary.org/obo/CL_0000766) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### myeloid lineage restricted progenitor cell `http://purl.obolibrary.org/obo/CL_0000839` + +#### Added +- [myeloid lineage restricted progenitor cell](http://purl.obolibrary.org/obo/CL_0000839) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### myoepithelial cell `http://purl.obolibrary.org/obo/CL_0000185` + +#### Added +- [myoepithelial cell](http://purl.obolibrary.org/obo/CL_0000185) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### myoepithelial cell of mammary gland `http://purl.obolibrary.org/obo/CL_0002324` + +#### Added +- [myoepithelial cell of mammary gland](http://purl.obolibrary.org/obo/CL_0002324) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### myoepithelium `http://purl.obolibrary.org/obo/UBERON_0000420` +#### Removed +- [myoepithelium](http://purl.obolibrary.org/obo/UBERON_0000420) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "myoepitheliocytus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Myoepithelial_cell" + +#### Added +- [myoepithelium](http://purl.obolibrary.org/obo/UBERON_0000420) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "myoepitheliocytus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Myoepithelial_cell" + + +### myofibroblast cell `http://purl.obolibrary.org/obo/CL_0000186` + +#### Added +- [myofibroblast cell](http://purl.obolibrary.org/obo/CL_0000186) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### myometrial cell `http://purl.obolibrary.org/obo/CL_0002366` + +#### Added +- [myometrial cell](http://purl.obolibrary.org/obo/CL_0002366) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### myometrium `http://purl.obolibrary.org/obo/UBERON_0001296` +#### Removed +- [myometrium](http://purl.obolibrary.org/obo/UBERON_0001296) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tunica muscularis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Myometrium" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [myometrium](http://purl.obolibrary.org/obo/UBERON_0001296) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tunica muscularis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Myometrium" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### myotome `http://purl.obolibrary.org/obo/UBERON_0003082` +#### Removed +- [myotome](http://purl.obolibrary.org/obo/UBERON_0003082) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "myotomus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Myotome" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [myotome](http://purl.obolibrary.org/obo/UBERON_0003082) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "myotomus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Myotome" + + +### nail plate `http://purl.obolibrary.org/obo/UBERON_0008198` +#### Removed +- [nail plate](http://purl.obolibrary.org/obo/UBERON_0008198) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "lamina unguis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Nail_plate" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [nail plate](http://purl.obolibrary.org/obo/UBERON_0008198) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "lamina unguis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Nail_plate" + + +### naive B cell `http://purl.obolibrary.org/obo/CL_0000788` + +#### Added +- [naive B cell](http://purl.obolibrary.org/obo/CL_0000788) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### naive T cell `http://purl.obolibrary.org/obo/CL_0000898` + +#### Added +- [naive T cell](http://purl.obolibrary.org/obo/CL_0000898) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### naive regulatory T cell `http://purl.obolibrary.org/obo/CL_0002677` + +#### Added +- [naive regulatory T cell](http://purl.obolibrary.org/obo/CL_0002677) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### naive thymus-derived CD4-positive, alpha-beta T cell `http://purl.obolibrary.org/obo/CL_0000895` + +#### Added +- [naive thymus-derived CD4-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000895) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### naive thymus-derived CD8-positive, alpha-beta T cell `http://purl.obolibrary.org/obo/CL_0000900` + +#### Added +- [naive thymus-derived CD8-positive, alpha-beta T cell](http://purl.obolibrary.org/obo/CL_0000900) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### nasal cartilage `http://purl.obolibrary.org/obo/UBERON_0001823` +#### Removed +- [nasal cartilage](http://purl.obolibrary.org/obo/UBERON_0001823) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D055171" + +#### Added +- [nasal cartilage](http://purl.obolibrary.org/obo/UBERON_0001823) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D055171" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [author_id](https://w3id.org/sssom/author_id) [0000-0001-9439-5346](https://orcid.org/0000-0001-9439-5346) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### nasal cavity `http://purl.obolibrary.org/obo/UBERON_0001707` +#### Removed +- [nasal cavity](http://purl.obolibrary.org/obo/UBERON_0001707) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cavitas nasi" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0002096" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Nasal_cavity" + +- [nasal cavity](http://purl.obolibrary.org/obo/UBERON_0001707) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cavum nasi" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Nasal_cavity" + +#### Added +- [nasal cavity](http://purl.obolibrary.org/obo/UBERON_0001707) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cavum nasi" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Nasal_cavity" + +- [nasal cavity](http://purl.obolibrary.org/obo/UBERON_0001707) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cavitas nasi" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0002096" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Nasal_cavity" + + +### nasal cavity mucosa `http://purl.obolibrary.org/obo/UBERON_0001826` +#### Removed +- [nasal cavity mucosa](http://purl.obolibrary.org/obo/UBERON_0001826) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica mucosa nasi" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:59684" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [nasal cavity mucosa](http://purl.obolibrary.org/obo/UBERON_0001826) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica mucosa nasi" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:59684" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### nasal mucosa goblet cell `http://purl.obolibrary.org/obo/CL_0002480` + +#### Added +- [nasal mucosa goblet cell](http://purl.obolibrary.org/obo/CL_0002480) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### nasal vestibule `http://purl.obolibrary.org/obo/UBERON_0000402` +#### Removed +- [nasal vestibule](http://purl.obolibrary.org/obo/UBERON_0000402) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vestibulum nasi" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Nasal_vestibule" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0001761" + +#### Added +- [nasal vestibule](http://purl.obolibrary.org/obo/UBERON_0000402) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vestibulum nasi" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Nasal_vestibule" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0001761" + + +### nasolacrimal duct `http://purl.obolibrary.org/obo/UBERON_0002392` +#### Removed +- [nasolacrimal duct](http://purl.obolibrary.org/obo/UBERON_0002392) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "d. nasolacrimalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Nasolacrimal_duct" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [nasolacrimal duct](http://purl.obolibrary.org/obo/UBERON_0002392) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "d. nasolacrimalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Nasolacrimal_duct" + + +### nasolacrimal groove `http://purl.obolibrary.org/obo/UBERON_0006266` +#### Removed +- [nasolacrimal groove](http://purl.obolibrary.org/obo/UBERON_0006266) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "s. lacrimalis maxillae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Lacrimal_groove" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [nasolacrimal groove](http://purl.obolibrary.org/obo/UBERON_0006266) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "s. lacrimalis maxillae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Lacrimal_groove" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### nasopharynx `http://purl.obolibrary.org/obo/UBERON_0001728` +#### Removed +- [nasopharynx](http://purl.obolibrary.org/obo/UBERON_0001728) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "pars nasalis pharyngis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Nasopharynx" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [nasopharynx](http://purl.obolibrary.org/obo/UBERON_0001728) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "pars nasalis pharyngis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Nasopharynx" + + +### natural T-regulatory cell `http://purl.obolibrary.org/obo/CL_0000903` + +#### Added +- [natural T-regulatory cell](http://purl.obolibrary.org/obo/CL_0000903) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### natural killer cell `http://purl.obolibrary.org/obo/CL_0000623` + +#### Added +- [natural killer cell](http://purl.obolibrary.org/obo/CL_0000623) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### near-projecting glutamatergic cortical neuron `http://purl.obolibrary.org/obo/CL_4023012` + +#### Added +- [near-projecting glutamatergic cortical neuron](http://purl.obolibrary.org/obo/CL_4023012) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### neck `http://purl.obolibrary.org/obo/UBERON_0000974` +#### Removed +- [neck](http://purl.obolibrary.org/obo/UBERON_0000974) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "collum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Neck" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [neck](http://purl.obolibrary.org/obo/UBERON_0000974) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "collum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Neck" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### neck of femur `http://purl.obolibrary.org/obo/UBERON_0007119` +#### Removed +- [neck of femur](http://purl.obolibrary.org/obo/UBERON_0007119) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "collum femoris" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Femur_neck" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [neck of femur](http://purl.obolibrary.org/obo/UBERON_0007119) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "collum femoris" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Femur_neck" + + +### neck of humerus `http://purl.obolibrary.org/obo/UBERON_4200172` +#### Removed +- [neck of humerus](http://purl.obolibrary.org/obo/UBERON_4200172) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "collum anatomicum humeri" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:23356" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [neck of humerus](http://purl.obolibrary.org/obo/UBERON_4200172) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "collum anatomicum humeri" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:23356" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### neck of rib `http://purl.obolibrary.org/obo/UBERON_0003253` +#### Removed +- [neck of rib](http://purl.obolibrary.org/obo/UBERON_0003253) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "collum costae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Neck_of_rib" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [neck of rib](http://purl.obolibrary.org/obo/UBERON_0003253) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "collum costae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Neck_of_rib" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [neck of rib](http://purl.obolibrary.org/obo/UBERON_0003253) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "collum costae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Neck_of_rib" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [neck of rib](http://purl.obolibrary.org/obo/UBERON_0003253) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "collum costae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Neck_of_rib" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### neck of tooth `http://purl.obolibrary.org/obo/UBERON_0015181` +#### Removed +- [neck of tooth](http://purl.obolibrary.org/obo/UBERON_0015181) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cervix dentis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [neck of tooth](http://purl.obolibrary.org/obo/UBERON_0015181) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "collumn dentis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ncithesaurus:Collum_Dentis" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [neck of tooth](http://purl.obolibrary.org/obo/UBERON_0015181) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cervix dentis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [neck of tooth](http://purl.obolibrary.org/obo/UBERON_0015181) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "collumn dentis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ncithesaurus:Collum_Dentis" + + +### neck of urinary bladder `http://purl.obolibrary.org/obo/UBERON_0001258` +#### Removed +- [neck of urinary bladder](http://purl.obolibrary.org/obo/UBERON_0001258) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cervix vesicae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:15912" + +- [neck of urinary bladder](http://purl.obolibrary.org/obo/UBERON_0001258) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "collum vesicae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:15912" + +- [neck of urinary bladder](http://purl.obolibrary.org/obo/UBERON_0001258) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cervix vesicae urinariae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Neck_of_urinary_bladder" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [neck of urinary bladder](http://purl.obolibrary.org/obo/UBERON_0001258) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cervix vesicae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:15912" + +- [neck of urinary bladder](http://purl.obolibrary.org/obo/UBERON_0001258) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cervix vesicae urinariae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Neck_of_urinary_bladder" + +- [neck of urinary bladder](http://purl.obolibrary.org/obo/UBERON_0001258) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "collum vesicae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:15912" + + +### negative regulation of amino acid biosynthetic process `http://purl.obolibrary.org/obo/GO_2000283` +#### Removed +- [negative regulation of amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_2000283) [created by](http://www.geneontology.org/formats/oboInOwl#created_by) "vw" + +- [negative regulation of amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_2000283) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of amino acid biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:obol" + +- [negative regulation of amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_2000283) [creation date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2010-12-10T11:54:23Z" + +- [negative regulation of amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_2000283) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of amino acid formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:obol" + +- [negative regulation of amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_2000283) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that stops, prevents or reduces the frequency, rate or extent of an amino acid biosynthetic process." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:obol" + +- [negative regulation of amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_2000283) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of cellular amino acid biosynthetic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:obol" + +- [negative regulation of amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_2000283) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [negative regulation of amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_2000283) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:2000283" + +- [negative regulation of amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_2000283) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of amino acid anabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:obol" + +- [negative regulation of amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_2000283) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of amino acid synthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:obol" + +- [negative regulation of amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_2000283) [label](http://www.w3.org/2000/01/rdf-schema#label) "negative regulation of amino acid biosynthetic process" + +- Class: [negative regulation of amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_2000283) + +- [negative regulation of amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_2000283) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0008652)) + +- [negative regulation of amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_2000283) SubClassOf [negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0008652) + +- [negative regulation of amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_2000283) SubClassOf [negative regulation of cellular amino acid metabolic process](http://purl.obolibrary.org/obo/GO_0045763) + +- [negative regulation of amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_2000283) SubClassOf [negative regulation of biosynthetic process](http://purl.obolibrary.org/obo/GO_0009890) + +- [negative regulation of amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_2000283) SubClassOf [regulation of cellular amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_2000282) + + + +### negative regulation of calcium ion import `http://purl.obolibrary.org/obo/GO_0090281` + +#### Added +- [negative regulation of calcium ion import](http://purl.obolibrary.org/obo/GO_0090281) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "negative regulation of transmembrane calcium influx" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:tb" + +- [negative regulation of calcium ion import](http://purl.obolibrary.org/obo/GO_0090281) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that decreases the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:BHF" + +- [negative regulation of calcium ion import](http://purl.obolibrary.org/obo/GO_0090281) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0090281" + +- [negative regulation of calcium ion import](http://purl.obolibrary.org/obo/GO_0090281) [label](http://www.w3.org/2000/01/rdf-schema#label) "negative regulation of calcium ion import" + +- [negative regulation of calcium ion import](http://purl.obolibrary.org/obo/GO_0090281) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [negative regulation of calcium ion import](http://purl.obolibrary.org/obo/GO_0090281) [creation date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2010-02-08T05:11:20Z" + +- [negative regulation of calcium ion import](http://purl.obolibrary.org/obo/GO_0090281) [created by](http://www.geneontology.org/formats/oboInOwl#created_by) "tb" + +- Class: [negative regulation of calcium ion import](http://purl.obolibrary.org/obo/GO_0090281) + +- [negative regulation of calcium ion import](http://purl.obolibrary.org/obo/GO_0090281) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [calcium ion import](http://purl.obolibrary.org/obo/GO_0070509)) + +- [negative regulation of calcium ion import](http://purl.obolibrary.org/obo/GO_0090281) SubClassOf [negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [calcium ion import](http://purl.obolibrary.org/obo/GO_0070509) + +- [negative regulation of calcium ion import](http://purl.obolibrary.org/obo/GO_0090281) SubClassOf [negative regulation of calcium ion transport](http://purl.obolibrary.org/obo/GO_0051926) + +- [negative regulation of calcium ion import](http://purl.obolibrary.org/obo/GO_0090281) SubClassOf [regulation of calcium ion import](http://purl.obolibrary.org/obo/GO_0090279) + + +### negative regulation of calcium ion import across plasma membrane `http://purl.obolibrary.org/obo/GO_1905949` + +#### Added +- [negative regulation of calcium ion import across plasma membrane](http://purl.obolibrary.org/obo/GO_1905949) SubClassOf [negative regulation of calcium ion import](http://purl.obolibrary.org/obo/GO_0090281) + + +### negative regulation of cellular amino acid metabolic process `http://purl.obolibrary.org/obo/GO_0045763` +#### Removed +- [negative regulation of cellular amino acid metabolic process](http://purl.obolibrary.org/obo/GO_0045763) SubClassOf [negative regulation of nitrogen compound metabolic process](http://purl.obolibrary.org/obo/GO_0051172) + +- [negative regulation of cellular amino acid metabolic process](http://purl.obolibrary.org/obo/GO_0045763) SubClassOf [negative regulation of small molecule metabolic process](http://purl.obolibrary.org/obo/GO_0062014) + +- [negative regulation of cellular amino acid metabolic process](http://purl.obolibrary.org/obo/GO_0045763) SubClassOf [negative regulation of cellular metabolic process](http://purl.obolibrary.org/obo/GO_0031324) + + + +### negative regulation of cytoplasmic transport `http://purl.obolibrary.org/obo/GO_1903650` +#### Removed +- [negative regulation of cytoplasmic transport](http://purl.obolibrary.org/obo/GO_1903650) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of cytoplasmic transport" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of cytoplasmic transport](http://purl.obolibrary.org/obo/GO_1903650) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic transport." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:25049409" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GO_REF:0000058" + +- [negative regulation of cytoplasmic transport](http://purl.obolibrary.org/obo/GO_1903650) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [negative regulation of cytoplasmic transport](http://purl.obolibrary.org/obo/GO_1903650) [has narrow synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "down regulation of cytoplasmic streaming" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of cytoplasmic transport](http://purl.obolibrary.org/obo/GO_1903650) [has narrow synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "inhibition of cytoplasmic streaming" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of cytoplasmic transport](http://purl.obolibrary.org/obo/GO_1903650) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of cytoplasmic transport" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of cytoplasmic transport](http://purl.obolibrary.org/obo/GO_1903650) [has narrow synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "negative regulation of cytoplasmic streaming" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of cytoplasmic transport](http://purl.obolibrary.org/obo/GO_1903650) [label](http://www.w3.org/2000/01/rdf-schema#label) "negative regulation of cytoplasmic transport" + +- [negative regulation of cytoplasmic transport](http://purl.obolibrary.org/obo/GO_1903650) [has narrow synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "down-regulation of cytoplasmic streaming" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of cytoplasmic transport](http://purl.obolibrary.org/obo/GO_1903650) [has narrow synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "inhibition of cytoplasmic transport" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of cytoplasmic transport](http://purl.obolibrary.org/obo/GO_1903650) [creation date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2014-11-24T13:38:26Z" + +- [negative regulation of cytoplasmic transport](http://purl.obolibrary.org/obo/GO_1903650) [created by](http://www.geneontology.org/formats/oboInOwl#created_by) "jl" + +- [negative regulation of cytoplasmic transport](http://purl.obolibrary.org/obo/GO_1903650) [has narrow synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "downregulation of cytoplasmic streaming" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of cytoplasmic transport](http://purl.obolibrary.org/obo/GO_1903650) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of cytoplasmic transport" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of cytoplasmic transport](http://purl.obolibrary.org/obo/GO_1903650) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1903650" + +- Class: [negative regulation of cytoplasmic transport](http://purl.obolibrary.org/obo/GO_1903650) + +- [negative regulation of cytoplasmic transport](http://purl.obolibrary.org/obo/GO_1903650) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [cytosolic transport](http://purl.obolibrary.org/obo/GO_0016482)) + +- [negative regulation of cytoplasmic transport](http://purl.obolibrary.org/obo/GO_1903650) SubClassOf [regulation of cytoplasmic transport](http://purl.obolibrary.org/obo/GO_1903649) + +- [negative regulation of cytoplasmic transport](http://purl.obolibrary.org/obo/GO_1903650) SubClassOf [negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [cytosolic transport](http://purl.obolibrary.org/obo/GO_0016482) + +- [negative regulation of cytoplasmic transport](http://purl.obolibrary.org/obo/GO_1903650) SubClassOf [negative regulation of intracellular transport](http://purl.obolibrary.org/obo/GO_0032387) + + + +### negative regulation of dense core granule transport `http://purl.obolibrary.org/obo/GO_1904810` +#### Removed +- [negative regulation of dense core granule transport](http://purl.obolibrary.org/obo/GO_1904810) SubClassOf [negative regulation of cytoplasmic transport](http://purl.obolibrary.org/obo/GO_1903650) + +#### Added +- [negative regulation of dense core granule transport](http://purl.obolibrary.org/obo/GO_1904810) SubClassOf [negative regulation of intracellular transport](http://purl.obolibrary.org/obo/GO_0032387) + + +### negative regulation of gamma-aminobutyric acid catabolic process `http://purl.obolibrary.org/obo/GO_1901716` + +#### Added +- [negative regulation of gamma-aminobutyric acid catabolic process](http://purl.obolibrary.org/obo/GO_1901716) SubClassOf [negative regulation of cellular metabolic process](http://purl.obolibrary.org/obo/GO_0031324) + +- [negative regulation of gamma-aminobutyric acid catabolic process](http://purl.obolibrary.org/obo/GO_1901716) SubClassOf [negative regulation of small molecule metabolic process](http://purl.obolibrary.org/obo/GO_0062014) + + +### negative regulation of glutamate metabolic process `http://purl.obolibrary.org/obo/GO_2000212` + +#### Added +- [negative regulation of glutamate metabolic process](http://purl.obolibrary.org/obo/GO_2000212) SubClassOf [negative regulation of small molecule metabolic process](http://purl.obolibrary.org/obo/GO_0062014) + +- [negative regulation of glutamate metabolic process](http://purl.obolibrary.org/obo/GO_2000212) SubClassOf [negative regulation of cellular metabolic process](http://purl.obolibrary.org/obo/GO_0031324) + + +### negative regulation of nitric oxide biosynthetic process `http://purl.obolibrary.org/obo/GO_0045019` +#### Removed +- [negative regulation of nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0045019) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of nitric oxide synthesis" + +- [negative regulation of nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0045019) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of nitric oxide biosynthetic process" + +- [negative regulation of nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0045019) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of nitric oxide anabolism" + +- [negative regulation of nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0045019) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0045019" + +- [negative regulation of nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0045019) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of nitric oxide biosynthetic process" + +- [negative regulation of nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0045019) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of nitric oxide biosynthesis" + +- [negative regulation of nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0045019) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of nitric oxide biosynthetic process" + +- [negative regulation of nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0045019) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [negative regulation of nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0045019) [has narrow synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "inhibition of nitric oxide biosynthetic process" + +- [negative regulation of nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0045019) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:go_curators" + +- [negative regulation of nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0045019) [label](http://www.w3.org/2000/01/rdf-schema#label) "negative regulation of nitric oxide biosynthetic process" + +- [negative regulation of nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0045019) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of nitric oxide formation" + +- Class: [negative regulation of nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0045019) + +- [negative regulation of nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0045019) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0006809)) + +- [negative regulation of nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0045019) SubClassOf [negative regulation of cellular biosynthetic process](http://purl.obolibrary.org/obo/GO_0031327) + +- [negative regulation of nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0045019) SubClassOf [regulation of nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0045428) + +- [negative regulation of nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0045019) SubClassOf [negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0006809) + +- [negative regulation of nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0045019) SubClassOf [negative regulation of nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_1904406) + +- [negative regulation of nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0045019) SubClassOf [negative regulation of nitrogen compound metabolic process](http://purl.obolibrary.org/obo/GO_0051172) + + + +### negative regulation of nitric oxide metabolic process `http://purl.obolibrary.org/obo/GO_1904406` +#### Removed +- [negative regulation of nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_1904406) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of nitric oxide metabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_1904406) [has narrow synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "inhibition of nitric oxide metabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_1904406) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of nitric oxide metabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_1904406) [created by](http://www.geneontology.org/formats/oboInOwl#created_by) "sl" + +- [negative regulation of nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_1904406) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [negative regulation of nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_1904406) [has narrow synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "inhibition of nitric oxide metabolic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_1904406) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1904406" + +- [negative regulation of nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_1904406) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that stops, prevents or reduces the frequency, rate or extent of nitric oxide metabolic process." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:11991626" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GO_REF:0000058" + +- [negative regulation of nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_1904406) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of nitric oxide metabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_1904406) [label](http://www.w3.org/2000/01/rdf-schema#label) "negative regulation of nitric oxide metabolic process" + +- [negative regulation of nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_1904406) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "downregulation of nitric oxide metabolic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_1904406) [creation date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2015-06-24T20:56:41Z" + +- [negative regulation of nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_1904406) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down-regulation of nitric oxide metabolic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_1904406) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "negative regulation of nitric oxide metabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [negative regulation of nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_1904406) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "down regulation of nitric oxide metabolic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- Class: [negative regulation of nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_1904406) + +- [negative regulation of nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_1904406) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_0046209)) + +- [negative regulation of nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_1904406) SubClassOf [negatively regulates](http://purl.obolibrary.org/obo/RO_0002212) some [nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_0046209) + +- [negative regulation of nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_1904406) SubClassOf [negative regulation of metabolic process](http://purl.obolibrary.org/obo/GO_0009892) + +- [negative regulation of nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_1904406) SubClassOf [regulation of nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_0080164) + + + +### neocortex `http://purl.obolibrary.org/obo/UBERON_0001950` +#### Removed +- [neocortex](http://purl.obolibrary.org/obo/UBERON_0001950) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus hypoglossalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:757" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [neocortex](http://purl.obolibrary.org/obo/UBERON_0001950) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus hypoglossalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:757" + + +### neoplastic cell `http://purl.obolibrary.org/obo/CL_0001063` + +#### Added +- [neoplastic cell](http://purl.obolibrary.org/obo/CL_0001063) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### nephrogenic cord `http://purl.obolibrary.org/obo/UBERON_0004875` +#### Removed +- [nephrogenic cord](http://purl.obolibrary.org/obo/UBERON_0004875) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "chorda nephrogenica" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Nephrogenic_cord" + +#### Added +- [nephrogenic cord](http://purl.obolibrary.org/obo/UBERON_0004875) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "chorda nephrogenica" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Nephrogenic_cord" + + +### nephron `http://purl.obolibrary.org/obo/UBERON_0001285` +#### Removed +- [nephron](http://purl.obolibrary.org/obo/UBERON_0001285) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tubulus renalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Nephron" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [nephron](http://purl.obolibrary.org/obo/UBERON_0001285) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nephroneum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Nephron" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [nephron](http://purl.obolibrary.org/obo/UBERON_0001285) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tubulus renalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Nephron" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [nephron](http://purl.obolibrary.org/obo/UBERON_0001285) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nephroneum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Nephron" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### nephron tubule epithelial cell `http://purl.obolibrary.org/obo/CL_1000494` + +#### Added +- [nephron tubule epithelial cell](http://purl.obolibrary.org/obo/CL_1000494) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### nerve `http://purl.obolibrary.org/obo/UBERON_0001021` +#### Removed +- [nerve](http://purl.obolibrary.org/obo/UBERON_0001021) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005105" + +#### Added +- [nerve](http://purl.obolibrary.org/obo/UBERON_0001021) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005105" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### nerve fasciculus `http://purl.obolibrary.org/obo/UBERON_0001019` +#### Removed +- [nerve fasciculus](http://purl.obolibrary.org/obo/UBERON_0001019) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "fasciculus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [nerve fasciculus](http://purl.obolibrary.org/obo/UBERON_0001019) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "fasciculus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### nerve fiber `http://purl.obolibrary.org/obo/UBERON_0006134` +#### Removed +- [nerve fiber](http://purl.obolibrary.org/obo/UBERON_0006134) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "neurofibra" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Nerve_fiber" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [nerve fiber](http://purl.obolibrary.org/obo/UBERON_0006134) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "neurofibra" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:5914" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [nerve fiber](http://purl.obolibrary.org/obo/UBERON_0006134) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "neurofibra" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Nerve_fiber" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [nerve fiber](http://purl.obolibrary.org/obo/UBERON_0006134) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "neurofibra" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:5914" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### nerve fiber layer of retina `http://purl.obolibrary.org/obo/UBERON_0001793` +#### Removed +- [nerve fiber layer of retina](http://purl.obolibrary.org/obo/UBERON_0001793) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "stratum neurofibrum retinae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Nerve_fiber_layer" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [nerve fiber layer of retina](http://purl.obolibrary.org/obo/UBERON_0001793) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "stratum neurofibrarum retinae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:58688" + +#### Added +- [nerve fiber layer of retina](http://purl.obolibrary.org/obo/UBERON_0001793) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "stratum neurofibrum retinae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Nerve_fiber_layer" + +- [nerve fiber layer of retina](http://purl.obolibrary.org/obo/UBERON_0001793) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "stratum neurofibrarum retinae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:58688" + + +### nerve of cervical vertebra `http://purl.obolibrary.org/obo/UBERON_0000962` +#### Removed +- [nerve of cervical vertebra](http://purl.obolibrary.org/obo/UBERON_0000962) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nervus cervicalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:5859" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [nerve of cervical vertebra](http://purl.obolibrary.org/obo/UBERON_0000962) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nervus cervicalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:5859" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### nerve root `http://purl.obolibrary.org/obo/UBERON_0002211` +#### Removed +- [nerve root](http://purl.obolibrary.org/obo/UBERON_0002211) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "radix nervi" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [nerve root](http://purl.obolibrary.org/obo/UBERON_0002211) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "radix nervi" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### nervous system `http://purl.obolibrary.org/obo/UBERON_0001016` +#### Removed +- [nervous system](http://purl.obolibrary.org/obo/UBERON_0001016) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "systema nervosum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Nervous_system" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [nervous system](http://purl.obolibrary.org/obo/UBERON_0001016) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005093" + +#### Added +- [nervous system](http://purl.obolibrary.org/obo/UBERON_0001016) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "systema nervosum" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Nervous_system" + +- [nervous system](http://purl.obolibrary.org/obo/UBERON_0001016) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005093" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + +- [nervous system](http://purl.obolibrary.org/obo/UBERON_0001016) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606) + +- [nervous system](http://purl.obolibrary.org/obo/UBERON_0001016) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [human_reference_atlas](http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas) + + +### neural arch `http://purl.obolibrary.org/obo/UBERON_0003861` +#### Removed +- [neural arch](http://purl.obolibrary.org/obo/UBERON_0003861) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arcus vertebrae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Vertebral_arch" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [neural arch](http://purl.obolibrary.org/obo/UBERON_0003861) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arcus vertebrae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Vertebral_arch" + + +### neural cell `http://purl.obolibrary.org/obo/CL_0002319` + +#### Added +- [neural cell](http://purl.obolibrary.org/obo/CL_0002319) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### neural crest `http://purl.obolibrary.org/obo/UBERON_0002342` +#### Removed +- [neural crest](http://purl.obolibrary.org/obo/UBERON_0002342) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "crista neuralis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Neural_crest" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [neural crest](http://purl.obolibrary.org/obo/UBERON_0002342) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "crista neuralis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Neural_crest" + + +### neural crest cell `http://purl.obolibrary.org/obo/CL_0011012` + +#### Added +- [neural crest cell](http://purl.obolibrary.org/obo/CL_0011012) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### neural plate `http://purl.obolibrary.org/obo/UBERON_0003075` +#### Removed +- [neural plate](http://purl.obolibrary.org/obo/UBERON_0003075) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D054258" + +- [neural plate](http://purl.obolibrary.org/obo/UBERON_0003075) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "lamina neuralis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Neural_plate" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [neural plate](http://purl.obolibrary.org/obo/UBERON_0003075) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "lamina neuralis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Neural_plate" + +- [neural plate](http://purl.obolibrary.org/obo/UBERON_0003075) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D054258" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [author_id](https://w3id.org/sssom/author_id) [0000-0001-9439-5346](https://orcid.org/0000-0001-9439-5346) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### neural progenitor cell `http://purl.obolibrary.org/obo/CL_0011020` + +#### Added +- [neural progenitor cell](http://purl.obolibrary.org/obo/CL_0011020) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### neural stem cell `http://purl.obolibrary.org/obo/CL_0000047` + +#### Added +- [neural stem cell](http://purl.obolibrary.org/obo/CL_0000047) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### neural tube `http://purl.obolibrary.org/obo/UBERON_0001049` +#### Removed +- [neural tube](http://purl.obolibrary.org/obo/UBERON_0001049) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D054259" + +- [neural tube](http://purl.obolibrary.org/obo/UBERON_0001049) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tubus neuralis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Neural_tube" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [neural tube](http://purl.obolibrary.org/obo/UBERON_0001049) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tubus neuralis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Neural_tube" + +- [neural tube](http://purl.obolibrary.org/obo/UBERON_0001049) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D054259" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [author_id](https://w3id.org/sssom/author_id) [0000-0001-9439-5346](https://orcid.org/0000-0001-9439-5346) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### neural tube alar plate `http://purl.obolibrary.org/obo/UBERON_0005882` +#### Removed +- [neural tube alar plate](http://purl.obolibrary.org/obo/UBERON_0005882) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "lamina dorsolateralis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Alar_plate" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [neural tube alar plate](http://purl.obolibrary.org/obo/UBERON_0005882) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "lamina alaris" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Alar_plate" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [neural tube alar plate](http://purl.obolibrary.org/obo/UBERON_0005882) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "lamina alaris" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Alar_plate" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [neural tube alar plate](http://purl.obolibrary.org/obo/UBERON_0005882) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "lamina dorsolateralis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Alar_plate" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### neurectoderm `http://purl.obolibrary.org/obo/UBERON_0002346` +#### Removed +- [neurectoderm](http://purl.obolibrary.org/obo/UBERON_0002346) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "epithelium tubi neuralis; neuroectoderma" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Neuroectoderm" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [neurectoderm](http://purl.obolibrary.org/obo/UBERON_0002346) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00001057" + +#### Added +- [neurectoderm](http://purl.obolibrary.org/obo/UBERON_0002346) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00001057" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + +- [neurectoderm](http://purl.obolibrary.org/obo/UBERON_0002346) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "epithelium tubi neuralis; neuroectoderma" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Neuroectoderm" + + +### neuroblast (sensu Vertebrata) `http://purl.obolibrary.org/obo/CL_0000031` + +#### Added +- [neuroblast (sensu Vertebrata)](http://purl.obolibrary.org/obo/CL_0000031) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### neuroendocrine cell `http://purl.obolibrary.org/obo/CL_0000165` + +#### Added +- [neuroendocrine cell](http://purl.obolibrary.org/obo/CL_0000165) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### neuroepithelial stem cell `http://purl.obolibrary.org/obo/CL_0002259` + +#### Added +- [neuroepithelial stem cell](http://purl.obolibrary.org/obo/CL_0002259) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### neurogenic placode `http://purl.obolibrary.org/obo/UBERON_0009955` +#### Removed +- [neurogenic placode](http://purl.obolibrary.org/obo/UBERON_0009955) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "placodae neurogenicae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Neurogenic_placodes" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [neurogenic placode](http://purl.obolibrary.org/obo/UBERON_0009955) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "placodae neurogenicae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Neurogenic_placodes" + + +### neurohypophysis `http://purl.obolibrary.org/obo/UBERON_0002198` +#### Removed +- [neurohypophysis](http://purl.obolibrary.org/obo/UBERON_0002198) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lobus posterior (glandula pituitaria)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:74628" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [neurohypophysis](http://purl.obolibrary.org/obo/UBERON_0002198) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "lobus nervosus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:401" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [neurohypophysis](http://purl.obolibrary.org/obo/UBERON_0002198) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lobus nervosus neurohypophysis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:74628" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [neurohypophysis](http://purl.obolibrary.org/obo/UBERON_0002198) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lobus posterior hypophysis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:74628" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [neurohypophysis](http://purl.obolibrary.org/obo/UBERON_0002198) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "lobus posterior" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:401" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [neurohypophysis](http://purl.obolibrary.org/obo/UBERON_0002198) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lobus posterior (glandula pituitaria)" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:74628" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [neurohypophysis](http://purl.obolibrary.org/obo/UBERON_0002198) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "lobus nervosus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:401" + +- [neurohypophysis](http://purl.obolibrary.org/obo/UBERON_0002198) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lobus nervosus neurohypophysis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:74628" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [neurohypophysis](http://purl.obolibrary.org/obo/UBERON_0002198) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lobus posterior hypophysis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:74628" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [neurohypophysis](http://purl.obolibrary.org/obo/UBERON_0002198) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "lobus posterior" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:401" + + +### neuromast `http://purl.obolibrary.org/obo/UBERON_0008904` +#### Removed +- [neuromast](http://purl.obolibrary.org/obo/UBERON_0008904) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0006219" + - [contributor](http://purl.org/dc/terms/contributor) "https://orcid.org/0000-0003-4423-4370" + +#### Added +- [neuromast](http://purl.obolibrary.org/obo/UBERON_0008904) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0006219" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + - [author_id](https://w3id.org/sssom/author_id) [0000-0003-4423-4370](https://orcid.org/0000-0003-4423-4370) + + +### neuron `http://purl.obolibrary.org/obo/CL_0000540` + +#### Added +- [neuron](http://purl.obolibrary.org/obo/CL_0000540) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### neuron associated cell `http://purl.obolibrary.org/obo/CL_0000095` + +#### Added +- [neuron associated cell](http://purl.obolibrary.org/obo/CL_0000095) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### neuron associated cell (sensu Vertebrata) `http://purl.obolibrary.org/obo/CL_0000123` + +#### Added +- [neuron associated cell (sensu Vertebrata)](http://purl.obolibrary.org/obo/CL_0000123) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### neuron projection bundle `http://purl.obolibrary.org/obo/UBERON_0000122` +#### Removed +- [neuron projection bundle](http://purl.obolibrary.org/obo/UBERON_0000122) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005099" + +#### Added +- [neuron projection bundle](http://purl.obolibrary.org/obo/UBERON_0000122) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005099" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### neuron projection bundle connecting eye with brain `http://purl.obolibrary.org/obo/UBERON_0004904` +#### Removed +- [neuron projection bundle connecting eye with brain](http://purl.obolibrary.org/obo/UBERON_0004904) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00001956" + +#### Added +- [neuron projection bundle connecting eye with brain](http://purl.obolibrary.org/obo/UBERON_0004904) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00001956" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### neuronal brush cell `http://purl.obolibrary.org/obo/CL_0000555` + +#### Added +- [neuronal brush cell](http://purl.obolibrary.org/obo/CL_0000555) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### neuronal receptor cell `http://purl.obolibrary.org/obo/CL_0000006` + +#### Added +- [neuronal receptor cell](http://purl.obolibrary.org/obo/CL_0000006) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### neutrophil `http://purl.obolibrary.org/obo/CL_0000775` + +#### Added +- [neutrophil](http://purl.obolibrary.org/obo/CL_0000775) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### neutrophil progenitor cell `http://purl.obolibrary.org/obo/CL_0000834` + +#### Added +- [neutrophil progenitor cell](http://purl.obolibrary.org/obo/CL_0000834) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### nipple `http://purl.obolibrary.org/obo/UBERON_0002030` +#### Removed +- [nipple](http://purl.obolibrary.org/obo/UBERON_0002030) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "papilla mammaria" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Nipple" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [nipple](http://purl.obolibrary.org/obo/UBERON_0002030) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "papilla mammaria" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Nipple" + + +### nitric oxide biosynthetic process `http://purl.obolibrary.org/obo/GO_0006809` +#### Removed +- [nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0006809) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nitric oxide formation" + +- [nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0006809) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0006809) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nitric oxide anabolism" + +- [nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0006809) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0006809" + +- [nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0006809) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the formation of nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" + +- [nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0006809) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nitric oxide biosynthesis" + +- [nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0006809) [label](http://www.w3.org/2000/01/rdf-schema#label) "nitric oxide biosynthetic process" + +- [nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0006809) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nitric oxide synthesis" + +- Class: [nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0006809) + +- [nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0006809) EquivalentTo [biosynthetic process](http://purl.obolibrary.org/obo/GO_0009058) and ([has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [CHEBI_16480](http://purl.obolibrary.org/obo/CHEBI_16480)) + +- [nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0006809) SubClassOf [nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_0046209) + +- [nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0006809) SubClassOf [cellular nitrogen compound biosynthetic process](http://purl.obolibrary.org/obo/GO_0044271) + +- [nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0006809) SubClassOf [has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [CHEBI_16480](http://purl.obolibrary.org/obo/CHEBI_16480) + + + +### nitric oxide catabolic process `http://purl.obolibrary.org/obo/GO_0046210` +#### Removed +- [nitric oxide catabolic process](http://purl.obolibrary.org/obo/GO_0046210) [label](http://www.w3.org/2000/01/rdf-schema#label) "nitric oxide catabolic process" + +- [nitric oxide catabolic process](http://purl.obolibrary.org/obo/GO_0046210) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [nitric oxide catabolic process](http://purl.obolibrary.org/obo/GO_0046210) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nitric oxide degradation" + +- [nitric oxide catabolic process](http://purl.obolibrary.org/obo/GO_0046210) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nitric oxide breakdown" + +- [nitric oxide catabolic process](http://purl.obolibrary.org/obo/GO_0046210) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0046210" + +- [nitric oxide catabolic process](http://purl.obolibrary.org/obo/GO_0046210) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nitric oxide catabolism" + +- [nitric oxide catabolic process](http://purl.obolibrary.org/obo/GO_0046210) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways resulting in the breakdown of nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" + +- Class: [nitric oxide catabolic process](http://purl.obolibrary.org/obo/GO_0046210) + +- [nitric oxide catabolic process](http://purl.obolibrary.org/obo/GO_0046210) EquivalentTo [catabolic process](http://purl.obolibrary.org/obo/GO_0009056) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [CHEBI_16480](http://purl.obolibrary.org/obo/CHEBI_16480)) + +- [nitric oxide catabolic process](http://purl.obolibrary.org/obo/GO_0046210) SubClassOf [nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_0046209) + +- [nitric oxide catabolic process](http://purl.obolibrary.org/obo/GO_0046210) SubClassOf [cellular nitrogen compound catabolic process](http://purl.obolibrary.org/obo/GO_0044270) + +- [nitric oxide catabolic process](http://purl.obolibrary.org/obo/GO_0046210) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [CHEBI_16480](http://purl.obolibrary.org/obo/CHEBI_16480) + + + +### nitric oxide metabolic process `http://purl.obolibrary.org/obo/GO_0046209` +#### Removed +- [nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_0046209) [label](http://www.w3.org/2000/01/rdf-schema#label) "nitric oxide metabolic process" + +- [nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_0046209) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_0046209) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The chemical reactions and pathways involving nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:ai" + +- [nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_0046209) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0046209" + +- [nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_0046209) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nitric oxide metabolism" + +- Class: [nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_0046209) + +- [nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_0046209) EquivalentTo [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) and ([has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [CHEBI_16480](http://purl.obolibrary.org/obo/CHEBI_16480)) + +- [nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_0046209) SubClassOf [metabolic process](http://purl.obolibrary.org/obo/GO_0008152) + +- [nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_0046209) SubClassOf [has primary input or output](http://purl.obolibrary.org/obo/RO_0004007) some [CHEBI_16480](http://purl.obolibrary.org/obo/CHEBI_16480) + + + +### nitric oxide production involved in inflammatory response `http://purl.obolibrary.org/obo/GO_0002537` +#### Removed +- [nitric oxide production involved in inflammatory response](http://purl.obolibrary.org/obo/GO_0002537) SubClassOf [has primary output](http://purl.obolibrary.org/obo/RO_0004008) some [CHEBI_16480](http://purl.obolibrary.org/obo/CHEBI_16480) + + + +### nitric oxide transmembrane transporter activity `http://purl.obolibrary.org/obo/GO_0030184` +#### Removed +- [nitric oxide transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0030184) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Enables the transfer of nitric oxide, nitrogen monoxide, from one side of a membrane to the other." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- [nitric oxide transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0030184) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "molecular_function" + +- [nitric oxide transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0030184) [label](http://www.w3.org/2000/01/rdf-schema#label) "nitric oxide transmembrane transporter activity" + +- [nitric oxide transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0030184) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0030184" + +- Class: [nitric oxide transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0030184) + +- [nitric oxide transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0030184) EquivalentTo [transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022857) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [CHEBI_16480](http://purl.obolibrary.org/obo/CHEBI_16480)) + +- [nitric oxide transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0030184) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [nitric oxide transport](http://purl.obolibrary.org/obo/GO_0030185) + +- [nitric oxide transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0030184) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [CHEBI_16480](http://purl.obolibrary.org/obo/CHEBI_16480) + +- [nitric oxide transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0030184) SubClassOf [transmembrane transporter activity](http://purl.obolibrary.org/obo/GO_0022857) + + + +### nitric oxide transport `http://purl.obolibrary.org/obo/GO_0030185` +#### Removed +- [nitric oxide transport](http://purl.obolibrary.org/obo/GO_0030185) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [nitric oxide transport](http://purl.obolibrary.org/obo/GO_0030185) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0030185" + +- [nitric oxide transport](http://purl.obolibrary.org/obo/GO_0030185) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The directed movement of nitric oxide, nitrogen monoxide, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + +- [nitric oxide transport](http://purl.obolibrary.org/obo/GO_0030185) [label](http://www.w3.org/2000/01/rdf-schema#label) "nitric oxide transport" + +- Class: [nitric oxide transport](http://purl.obolibrary.org/obo/GO_0030185) + +- [nitric oxide transport](http://purl.obolibrary.org/obo/GO_0030185) EquivalentTo [transport](http://purl.obolibrary.org/obo/GO_0006810) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [CHEBI_16480](http://purl.obolibrary.org/obo/CHEBI_16480)) + +- [nitric oxide transport](http://purl.obolibrary.org/obo/GO_0030185) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [CHEBI_16480](http://purl.obolibrary.org/obo/CHEBI_16480) + +- [nitric oxide transport](http://purl.obolibrary.org/obo/GO_0030185) SubClassOf [transport](http://purl.obolibrary.org/obo/GO_0006810) + + + +### nitrogen compound metabolic process `http://purl.obolibrary.org/obo/GO_0006807` + +#### Added +- [nitrogen compound metabolic process](http://purl.obolibrary.org/obo/GO_0006807) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) "https://github.com/geneontology/go-ontology/issues/26424"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + +- [nitrogen compound metabolic process](http://purl.obolibrary.org/obo/GO_0006807) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [gocheck_do_not_annotate](http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate) + + +### nitrogen cycle metabolic process `http://purl.obolibrary.org/obo/GO_0071941` +#### Removed +- [nitrogen cycle metabolic process](http://purl.obolibrary.org/obo/GO_0071941) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [prokaryote_subset](http://purl.obolibrary.org/obo/go#prokaryote_subset) + +#### Added +- [nitrogen cycle metabolic process](http://purl.obolibrary.org/obo/GO_0071941) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_prokaryote](http://purl.obolibrary.org/obo/go#goslim_prokaryote) + + +### non-classical monocyte `http://purl.obolibrary.org/obo/CL_0000875` + +#### Added +- [non-classical monocyte](http://purl.obolibrary.org/obo/CL_0000875) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### non-connected functional system `http://purl.obolibrary.org/obo/UBERON_0015203` +#### Removed +- [non-connected functional system](http://purl.obolibrary.org/obo/UBERON_0015203) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007278" + +#### Added +- [non-connected functional system](http://purl.obolibrary.org/obo/UBERON_0015203) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007278" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### non-pigmented ciliary epithelial cell `http://purl.obolibrary.org/obo/CL_0002304` + +#### Added +- [non-pigmented ciliary epithelial cell](http://purl.obolibrary.org/obo/CL_0002304) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### non-terminally differentiated cell `http://purl.obolibrary.org/obo/CL_0000055` + +#### Added +- [non-terminally differentiated cell](http://purl.obolibrary.org/obo/CL_0000055) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### nose `http://purl.obolibrary.org/obo/UBERON_0000004` +#### Removed +- [nose](http://purl.obolibrary.org/obo/UBERON_0000004) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nasus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Nose" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [nose](http://purl.obolibrary.org/obo/UBERON_0000004) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nasus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Nose" + + +### notochord `http://purl.obolibrary.org/obo/UBERON_0002328` +#### Removed +- [notochord](http://purl.obolibrary.org/obo/UBERON_0002328) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "notochorda" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Notochord" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [notochord](http://purl.obolibrary.org/obo/UBERON_0002328) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "notochorda" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Notochord" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### nuchal ligament `http://purl.obolibrary.org/obo/UBERON_0000351` +#### Removed +- [nuchal ligament](http://purl.obolibrary.org/obo/UBERON_0000351) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ligamentum nuchae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:13427" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [nuchal ligament](http://purl.obolibrary.org/obo/UBERON_0000351) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ligamentum nuchae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:13427" + + +### nucleus accumbens `http://purl.obolibrary.org/obo/UBERON_0001882` +#### Removed +- [nucleus accumbens](http://purl.obolibrary.org/obo/UBERON_0001882) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "colliculus nuclei caudati" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:277" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [nucleus accumbens](http://purl.obolibrary.org/obo/UBERON_0001882) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "colliculus nuclei caudati" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:277" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### nucleus of lateral olfactory tract `http://purl.obolibrary.org/obo/UBERON_0002893` +#### Removed +- [nucleus of lateral olfactory tract](http://purl.obolibrary.org/obo/UBERON_0002893) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus striae olfactoriae lateralis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:242" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [nucleus of lateral olfactory tract](http://purl.obolibrary.org/obo/UBERON_0002893) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus of tractus olfactorius lateralis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:242" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [nucleus of lateral olfactory tract](http://purl.obolibrary.org/obo/UBERON_0002893) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus striae olfactoriae lateralis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:242" + +- [nucleus of lateral olfactory tract](http://purl.obolibrary.org/obo/UBERON_0002893) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus of tractus olfactorius lateralis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:242" + + +### nucleus pulposus `http://purl.obolibrary.org/obo/UBERON_0002242` +#### Removed +- [nucleus pulposus](http://purl.obolibrary.org/obo/UBERON_0002242) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D000070614" + +#### Added +- [nucleus pulposus](http://purl.obolibrary.org/obo/UBERON_0002242) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D000070614" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [author_id](https://w3id.org/sssom/author_id) [0000-0001-9439-5346](https://orcid.org/0000-0001-9439-5346) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### obsolete L2/3 pvalb-like sst GABAergic cortical interneuron (Mus musculus) `http://purl.obolibrary.org/obo/CL_4023034` +#### Removed +- [obsolete L2/3 pvalb-like sst GABAergic cortical interneuron (Mus musculus)](http://purl.obolibrary.org/obo/CL_4023034) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "Moved to PCL - see https://github.com/obophenotype/brain_data_standards_ontologies/issues/231. Use PCL:1000002 instead." + +#### Added +- [obsolete L2/3 pvalb-like sst GABAergic cortical interneuron (Mus musculus)](http://purl.obolibrary.org/obo/CL_4023034) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "Moved to PCL. Use PCL:1000002 instead." + +- [obsolete L2/3 pvalb-like sst GABAergic cortical interneuron (Mus musculus)](http://purl.obolibrary.org/obo/CL_4023034) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) [231](https://github.com/obophenotype/brain_data_standards_ontologies/issues/231) + + +### obsolete Martinotti morphology L2/3 pvalb-like sst GABAergic cortical interneuron (Mus musculus) `http://purl.obolibrary.org/obo/CL_4023067` +#### Removed +- [obsolete Martinotti morphology L2/3 pvalb-like sst GABAergic cortical interneuron (Mus musculus)](http://purl.obolibrary.org/obo/CL_4023067) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "Moved to PCL - see https://github.com/obophenotype/brain_data_standards_ontologies/issues/231. Use PCL:1000004 instead." + +#### Added +- [obsolete Martinotti morphology L2/3 pvalb-like sst GABAergic cortical interneuron (Mus musculus)](http://purl.obolibrary.org/obo/CL_4023067) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "Moved to PCL. Use PCL:1000004 instead." + +- [obsolete Martinotti morphology L2/3 pvalb-like sst GABAergic cortical interneuron (Mus musculus)](http://purl.obolibrary.org/obo/CL_4023067) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) [231](https://github.com/obophenotype/brain_data_standards_ontologies/issues/231) + + +### obsolete acid secreting cell `http://purl.obolibrary.org/obo/CL_0000161` +#### Removed +- [obsolete acid secreting cell](http://purl.obolibrary.org/obo/CL_0000161) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "https://github.com/obophenotype/cell-ontology/issues/427" + +#### Added +- [obsolete acid secreting cell](http://purl.obolibrary.org/obo/CL_0000161) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) [427](https://github.com/obophenotype/cell-ontology/issues/427) + + +### obsolete animal cell `http://purl.obolibrary.org/obo/CL_0000548` +#### Removed +- [obsolete animal cell](http://purl.obolibrary.org/obo/CL_0000548) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "https://github.com/obophenotype/cell-ontology/issues/2124" + +#### Added +- [obsolete animal cell](http://purl.obolibrary.org/obo/CL_0000548) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + +- [obsolete animal cell](http://purl.obolibrary.org/obo/CL_0000548) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) [2124](https://github.com/obophenotype/cell-ontology/issues/2124) + + +### obsolete barrier epithelial cell `http://purl.obolibrary.org/obo/CL_0000073` +#### Removed +- [obsolete barrier epithelial cell](http://purl.obolibrary.org/obo/CL_0000073) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "https://github.com/obophenotype/cell-ontology/issues/1149" + +#### Added +- [obsolete barrier epithelial cell](http://purl.obolibrary.org/obo/CL_0000073) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) [1149](https://github.com/obophenotype/cell-ontology/issues/1149) + + +### obsolete basket morphology L2/3 pvalb-like sst GABAergic cortical interneuron (Mus musculus) `http://purl.obolibrary.org/obo/CL_4023078` +#### Removed +- [obsolete basket morphology L2/3 pvalb-like sst GABAergic cortical interneuron (Mus musculus)](http://purl.obolibrary.org/obo/CL_4023078) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "Moved to PCL - see https://github.com/obophenotype/brain_data_standards_ontologies/issues/231. Use PCL:1000003 instead." + +#### Added +- [obsolete basket morphology L2/3 pvalb-like sst GABAergic cortical interneuron (Mus musculus)](http://purl.obolibrary.org/obo/CL_4023078) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "Moved to PCL. Use PCL:1000003 instead." + +- [obsolete basket morphology L2/3 pvalb-like sst GABAergic cortical interneuron (Mus musculus)](http://purl.obolibrary.org/obo/CL_4023078) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) [231](https://github.com/obophenotype/brain_data_standards_ontologies/issues/231) + + +### obsolete bronchioalveolar stem cells `http://purl.obolibrary.org/obo/CL_1001566` +#### Removed +- [obsolete bronchioalveolar stem cells](http://purl.obolibrary.org/obo/CL_1001566) [see also](http://www.w3.org/2000/01/rdf-schema#seeAlso) "https://github.com/obophenotype/cell-ontology/issues/1443" + +#### Added +- [obsolete bronchioalveolar stem cells](http://purl.obolibrary.org/obo/CL_1001566) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) [1443](https://github.com/obophenotype/cell-ontology/issues/1443) + + +### obsolete choroid plexus cell `http://purl.obolibrary.org/obo/CL_4023073` +#### Removed +- [obsolete choroid plexus cell](http://purl.obolibrary.org/obo/CL_4023073) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "https://github.com/obophenotype/cell-ontology/issues/2043" + +#### Added +- [obsolete choroid plexus cell](http://purl.obolibrary.org/obo/CL_4023073) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) [2043](https://github.com/obophenotype/cell-ontology/issues/2043) + + +### obsolete closable valve cell `http://purl.obolibrary.org/obo/CL_0000664` +#### Removed +- [obsolete closable valve cell](http://purl.obolibrary.org/obo/CL_0000664) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "https://github.com/obophenotype/cell-ontology/issues/726" + +#### Added +- [obsolete closable valve cell](http://purl.obolibrary.org/obo/CL_0000664) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) [726](https://github.com/obophenotype/cell-ontology/issues/726) + + +### obsolete excitatory neuron `http://purl.obolibrary.org/obo/CL_0008030` +#### Removed +- [obsolete excitatory neuron](http://purl.obolibrary.org/obo/CL_0008030) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "See https://github.com/obophenotype/cell-ontology/issues/1540. Consider using glutamatergic neuron instead. Do note that not all glutamatergic neurons are excitatory and replacing excitatory neuron with glutamatergic neuron should be done with caution." + +#### Added +- [obsolete excitatory neuron](http://purl.obolibrary.org/obo/CL_0008030) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) [1540](https://github.com/obophenotype/cell-ontology/issues/1540) + +- [obsolete excitatory neuron](http://purl.obolibrary.org/obo/CL_0008030) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "Consider using glutamatergic neuron instead. Do note that not all glutamatergic neurons are excitatory and replacing excitatory neuron with glutamatergic neuron should be done with caution." + + +### obsolete female germ line stem cell (sensu Nematoda and Protostomia) `http://purl.obolibrary.org/obo/CL_0000088` +#### Removed +- [obsolete female germ line stem cell (sensu Nematoda and Protostomia)](http://purl.obolibrary.org/obo/CL_0000088) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) "https://github.com/obophenotype/cell-ontology/issues/1935" + +#### Added +- [obsolete female germ line stem cell (sensu Nematoda and Protostomia)](http://purl.obolibrary.org/obo/CL_0000088) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) [1935](https://github.com/obophenotype/cell-ontology/issues/1935) + + +### obsolete female germ line stem cell (sensu Vertebrata) `http://purl.obolibrary.org/obo/CL_0000090` +#### Removed +- [obsolete female germ line stem cell (sensu Vertebrata)](http://purl.obolibrary.org/obo/CL_0000090) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) "https://github.com/obophenotype/cell-ontology/issues/1935" + +#### Added +- [obsolete female germ line stem cell (sensu Vertebrata)](http://purl.obolibrary.org/obo/CL_0000090) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) [1935](https://github.com/obophenotype/cell-ontology/issues/1935) + + +### obsolete fusimotor neuron `http://purl.obolibrary.org/obo/CL_0000717` +#### Removed +- [obsolete fusimotor neuron](http://purl.obolibrary.org/obo/CL_0000717) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "Term merged into CL:0008037. Refer to https://github.com/obophenotype/cell-ontology/issues/1364" + +#### Added +- [obsolete fusimotor neuron](http://purl.obolibrary.org/obo/CL_0000717) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) [1364](https://github.com/obophenotype/cell-ontology/issues/1364) + +- [obsolete fusimotor neuron](http://purl.obolibrary.org/obo/CL_0000717) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "Term merged into CL:0008037." + + +### obsolete germ line stem cell (sensu Nematoda and Protostomia) `http://purl.obolibrary.org/obo/CL_0000086` +#### Removed +- [obsolete germ line stem cell (sensu Nematoda and Protostomia)](http://purl.obolibrary.org/obo/CL_0000086) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) "https://github.com/obophenotype/cell-ontology/issues/1935" + +#### Added +- [obsolete germ line stem cell (sensu Nematoda and Protostomia)](http://purl.obolibrary.org/obo/CL_0000086) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) [1935](https://github.com/obophenotype/cell-ontology/issues/1935) + + +### obsolete germ line stem cell (sensu Vertebrata) `http://purl.obolibrary.org/obo/CL_0000085` +#### Removed +- [obsolete germ line stem cell (sensu Vertebrata)](http://purl.obolibrary.org/obo/CL_0000085) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) "https://github.com/obophenotype/cell-ontology/issues/1935" + +#### Added +- [obsolete germ line stem cell (sensu Vertebrata)](http://purl.obolibrary.org/obo/CL_0000085) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) [1935](https://github.com/obophenotype/cell-ontology/issues/1935) + + +### obsolete glial cell (sensu Nematoda and Protostomia) `http://purl.obolibrary.org/obo/CL_0000124` +#### Removed +- [obsolete glial cell (sensu Nematoda and Protostomia)](http://purl.obolibrary.org/obo/CL_0000124) [see also](http://www.w3.org/2000/01/rdf-schema#seeAlso) "https://github.com/obophenotype/cell-ontology/issues/715" + +#### Added +- [obsolete glial cell (sensu Nematoda and Protostomia)](http://purl.obolibrary.org/obo/CL_0000124) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) [715](https://github.com/obophenotype/cell-ontology/issues/715) + + +### obsolete glial cell (sensu Vertebrata) `http://purl.obolibrary.org/obo/CL_0000243` +#### Removed +- [obsolete glial cell (sensu Vertebrata)](http://purl.obolibrary.org/obo/CL_0000243) [see also](http://www.w3.org/2000/01/rdf-schema#seeAlso) "https://github.com/obophenotype/cell-ontology/issues/715" + +#### Added +- [obsolete glial cell (sensu Vertebrata)](http://purl.obolibrary.org/obo/CL_0000243) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) [715](https://github.com/obophenotype/cell-ontology/issues/715) + + +### obsolete has_high_plasma_membrane_amount `http://purl.obolibrary.org/obo/cl#has_high_plasma_membrane_amount` +#### Removed +- [obsolete has_high_plasma_membrane_amount](http://purl.obolibrary.org/obo/cl#has_high_plasma_membrane_amount) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "Replaced with RO:0015015, see https://github.com/obophenotype/cell-ontology/issues/1481" + +#### Added +- [obsolete has_high_plasma_membrane_amount](http://purl.obolibrary.org/obo/cl#has_high_plasma_membrane_amount) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) [1481](https://github.com/obophenotype/cell-ontology/issues/1481) + + +### obsolete has_low_plasma_membrane_amount `http://purl.obolibrary.org/obo/cl#has_low_plasma_membrane_amount` +#### Removed +- [obsolete has_low_plasma_membrane_amount](http://purl.obolibrary.org/obo/cl#has_low_plasma_membrane_amount) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "Replaced with RO:0015016, see https://github.com/obophenotype/cell-ontology/issues/1481" + +#### Added +- [obsolete has_low_plasma_membrane_amount](http://purl.obolibrary.org/obo/cl#has_low_plasma_membrane_amount) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) [1481](https://github.com/obophenotype/cell-ontology/issues/1481) + + +### obsolete increased nucleus size `http://purl.obolibrary.org/obo/CL_0017505` +#### Removed +- [obsolete increased nucleus size](http://purl.obolibrary.org/obo/CL_0017505) [label](http://www.w3.org/2000/01/rdf-schema#label) "increased nucleus size" + +- [obsolete increased nucleus size](http://purl.obolibrary.org/obo/CL_0017505) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A nucleus size quality which is relatively high compared to the amount of cytoplasm present in the same cell." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:tfm" + +- [obsolete increased nucleus size](http://purl.obolibrary.org/obo/CL_0017505) EquivalentTo [nucleus](http://purl.obolibrary.org/obo/GO_0005634) and ([bearer of](http://purl.obolibrary.org/obo/RO_0000053) some [increased size](http://purl.obolibrary.org/obo/PATO_0000586)) + +- [obsolete increased nucleus size](http://purl.obolibrary.org/obo/CL_0017505) SubClassOf [bearer of](http://purl.obolibrary.org/obo/RO_0000053) some [increased size](http://purl.obolibrary.org/obo/PATO_0000586) + +- [obsolete increased nucleus size](http://purl.obolibrary.org/obo/CL_0017505) SubClassOf [nucleus](http://purl.obolibrary.org/obo/GO_0005634) + +#### Added +- [obsolete increased nucleus size](http://purl.obolibrary.org/obo/CL_0017505) [deprecated](http://www.w3.org/2002/07/owl#deprecated) true + +- [obsolete increased nucleus size](http://purl.obolibrary.org/obo/CL_0017505) [term replaced by](http://purl.obolibrary.org/obo/IAO_0100001) [high nuclear/cytoplasmic ratio](http://purl.obolibrary.org/obo/PATO_0040072) + +- [obsolete increased nucleus size](http://purl.obolibrary.org/obo/CL_0017505) [label](http://www.w3.org/2000/01/rdf-schema#label) "obsolete increased nucleus size" + +- [obsolete increased nucleus size](http://purl.obolibrary.org/obo/CL_0017505) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "OBSOLETE. A nucleus size quality which is relatively high compared to the amount of cytoplasm present in the same cell." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:tfm" + +- [obsolete increased nucleus size](http://purl.obolibrary.org/obo/CL_0017505) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) [2251](https://github.com/obophenotype/cell-ontology/issues/2251) + +- [obsolete increased nucleus size](http://purl.obolibrary.org/obo/CL_0017505) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "This class was a phenotype, not a cell type." + + +### obsolete inhibitory neuron `http://purl.obolibrary.org/obo/CL_0008029` +#### Removed +- [obsolete inhibitory neuron](http://purl.obolibrary.org/obo/CL_0008029) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "See https://github.com/obophenotype/cell-ontology/issues/1540. Consider GABAergic neuron or inhibitory interneuron instead. Do note that not all GABAergic neurons are inhibitory (see PMID:12209121) and replacing inhibitory neuron with GABAergic neuron should be done with caution." + +#### Added +- [obsolete inhibitory neuron](http://purl.obolibrary.org/obo/CL_0008029) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "Consider GABAergic neuron or inhibitory interneuron instead. Do note that not all GABAergic neurons are inhibitory (see PMID:12209121) and replacing inhibitory neuron with GABAergic neuron should be done with caution." + +- [obsolete inhibitory neuron](http://purl.obolibrary.org/obo/CL_0008029) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) [1540](https://github.com/obophenotype/cell-ontology/issues/1540) + + +### obsolete lobed nucleus `http://purl.obolibrary.org/obo/CL_0017501` +#### Removed +- [obsolete lobed nucleus](http://purl.obolibrary.org/obo/CL_0017501) [see also](http://www.w3.org/2000/01/rdf-schema#seeAlso) "https://github.com/obophenotype/cell-ontology/issues/734" + +#### Added +- [obsolete lobed nucleus](http://purl.obolibrary.org/obo/CL_0017501) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) [734](https://github.com/obophenotype/cell-ontology/issues/734) + + +### obsolete macrophage (sensu Diptera) `http://purl.obolibrary.org/obo/CL_0000401` +#### Removed +- [obsolete macrophage (sensu Diptera)](http://purl.obolibrary.org/obo/CL_0000401) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) "https://github.com/obophenotype/cell-ontology/issues/1949" + +#### Added +- [obsolete macrophage (sensu Diptera)](http://purl.obolibrary.org/obo/CL_0000401) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) [1949](https://github.com/obophenotype/cell-ontology/issues/1949) + + +### obsolete male germ line stem cell (sensu Nematoda and Protostomia) `http://purl.obolibrary.org/obo/CL_0000087` +#### Removed +- [obsolete male germ line stem cell (sensu Nematoda and Protostomia)](http://purl.obolibrary.org/obo/CL_0000087) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) "https://github.com/obophenotype/cell-ontology/issues/1935" + +#### Added +- [obsolete male germ line stem cell (sensu Nematoda and Protostomia)](http://purl.obolibrary.org/obo/CL_0000087) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) [1935](https://github.com/obophenotype/cell-ontology/issues/1935) + + +### obsolete male germ line stem cell (sensu Vertebrata) `http://purl.obolibrary.org/obo/CL_0000089` +#### Removed +- [obsolete male germ line stem cell (sensu Vertebrata)](http://purl.obolibrary.org/obo/CL_0000089) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) "https://github.com/obophenotype/cell-ontology/issues/1935" + +#### Added +- [obsolete male germ line stem cell (sensu Vertebrata)](http://purl.obolibrary.org/obo/CL_0000089) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) [1935](https://github.com/obophenotype/cell-ontology/issues/1935) + + +### obsolete metabolising cell `http://purl.obolibrary.org/obo/CL_0000181` +#### Removed +- [obsolete metabolising cell](http://purl.obolibrary.org/obo/CL_0000181) [see also](http://www.w3.org/2000/01/rdf-schema#seeAlso) "https://github.com/obophenotype/cell-ontology/issues/720" + +#### Added +- [obsolete metabolising cell](http://purl.obolibrary.org/obo/CL_0000181) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) [720](https://github.com/obophenotype/cell-ontology/issues/720) + + +### obsolete native cell `http://purl.obolibrary.org/obo/CL_0000003` +#### Removed +- [obsolete native cell](http://purl.obolibrary.org/obo/CL_0000003) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "https://github.com/obophenotype/cell-ontology/issues/2124" + +#### Added +- [obsolete native cell](http://purl.obolibrary.org/obo/CL_0000003) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) [2124](https://github.com/obophenotype/cell-ontology/issues/2124) + +- [obsolete native cell](http://purl.obolibrary.org/obo/CL_0000003) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### obsolete neuroepidermoblast `http://purl.obolibrary.org/obo/CL_0000405` +#### Removed +- [obsolete neuroepidermoblast](http://purl.obolibrary.org/obo/CL_0000405) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) "https://github.com/FlyBase/drosophila-anatomy-developmental-ontology/issues/1621" + +#### Added +- [obsolete neuroepidermoblast](http://purl.obolibrary.org/obo/CL_0000405) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) [1621](https://github.com/FlyBase/drosophila-anatomy-developmental-ontology/issues/1621) + + +### obsolete neurosecretory neuron `http://purl.obolibrary.org/obo/CL_0000381` +#### Removed +- [obsolete neurosecretory neuron](http://purl.obolibrary.org/obo/CL_0000381) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "https://github.com/obophenotype/cell-ontology/issues/1784 +'neuroendocrine cell' (which has exact synonym "neurosecretory cell") and 'neurosecretory neuron' may all refer to the same cell type." + +#### Added +- [obsolete neurosecretory neuron](http://purl.obolibrary.org/obo/CL_0000381) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) [1784](https://github.com/obophenotype/cell-ontology/issues/1784) + +- [obsolete neurosecretory neuron](http://purl.obolibrary.org/obo/CL_0000381) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "'neuroendocrine cell' (which has exact synonym "neurosecretory cell") and 'neurosecretory neuron' may all refer to the same cell type." + + +### obsolete peripheral neuron `http://purl.obolibrary.org/obo/CL_0000111` +#### Removed +- [obsolete peripheral neuron](http://purl.obolibrary.org/obo/CL_0000111) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "Merging into CL:2000032, see https://github.com/obophenotype/cell-ontology/issues/1069" + +#### Added +- [obsolete peripheral neuron](http://purl.obolibrary.org/obo/CL_0000111) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "Merging into CL:2000032." + +- [obsolete peripheral neuron](http://purl.obolibrary.org/obo/CL_0000111) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) [1069](https://github.com/obophenotype/cell-ontology/issues/1069) + + +### obsolete permanently open valve cell `http://purl.obolibrary.org/obo/CL_0000665` +#### Removed +- [obsolete permanently open valve cell](http://purl.obolibrary.org/obo/CL_0000665) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "https://github.com/obophenotype/cell-ontology/issues/726" + +#### Added +- [obsolete permanently open valve cell](http://purl.obolibrary.org/obo/CL_0000665) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) [726](https://github.com/obophenotype/cell-ontology/issues/726) + + +### obsolete podocyte (sensu Diptera) `http://purl.obolibrary.org/obo/CL_0000391` +#### Removed +- [obsolete podocyte (sensu Diptera)](http://purl.obolibrary.org/obo/CL_0000391) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) "https://github.com/obophenotype/cell-ontology/issues/1949" + +#### Added +- [obsolete podocyte (sensu Diptera)](http://purl.obolibrary.org/obo/CL_0000391) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) [1949](https://github.com/obophenotype/cell-ontology/issues/1949) + + +### obsolete polygonal cell `http://purl.obolibrary.org/obo/CL_0000398` +#### Removed +- [obsolete polygonal cell](http://purl.obolibrary.org/obo/CL_0000398) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) "https://github.com/obophenotype/cell-ontology/issues/1949" + +#### Added +- [obsolete polygonal cell](http://purl.obolibrary.org/obo/CL_0000398) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) [1949](https://github.com/obophenotype/cell-ontology/issues/1949) + + +### obsolete primary pigment cell `http://purl.obolibrary.org/obo/CL_0000727` +#### Removed +- [obsolete primary pigment cell](http://purl.obolibrary.org/obo/CL_0000727) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) "https://github.com/obophenotype/cell-ontology/issues/1930" + +#### Added +- [obsolete primary pigment cell](http://purl.obolibrary.org/obo/CL_0000727) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) [1930](https://github.com/obophenotype/cell-ontology/issues/1930) + + +### obsolete scaffold cell `http://purl.obolibrary.org/obo/CL_0000426` +#### Removed +- [obsolete scaffold cell](http://purl.obolibrary.org/obo/CL_0000426) [see also](http://www.w3.org/2000/01/rdf-schema#seeAlso) "https://github.com/obophenotype/cell-ontology/issues/708" + +#### Added +- [obsolete scaffold cell](http://purl.obolibrary.org/obo/CL_0000426) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) [708](https://github.com/obophenotype/cell-ontology/issues/708) + + +### obsolete secondary pigment cell `http://purl.obolibrary.org/obo/CL_0000728` +#### Removed +- [obsolete secondary pigment cell](http://purl.obolibrary.org/obo/CL_0000728) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) "https://github.com/obophenotype/cell-ontology/issues/1930" + +#### Added +- [obsolete secondary pigment cell](http://purl.obolibrary.org/obo/CL_0000728) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) [1930](https://github.com/obophenotype/cell-ontology/issues/1930) + + +### obsolete seminal fluid secreting cell `http://purl.obolibrary.org/obo/CL_0000321` +#### Removed +- [obsolete seminal fluid secreting cell](http://purl.obolibrary.org/obo/CL_0000321) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "https://github.com/obophenotype/cell-ontology/issues/1149" + +#### Added +- [obsolete seminal fluid secreting cell](http://purl.obolibrary.org/obo/CL_0000321) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) [1149](https://github.com/obophenotype/cell-ontology/issues/1149) + + +### obsolete somatic cell `http://purl.obolibrary.org/obo/CL_0002371` +#### Removed +- [obsolete somatic cell](http://purl.obolibrary.org/obo/CL_0002371) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "https://github.com/obophenotype/cell-ontology/issues/1150" + +#### Added +- [obsolete somatic cell](http://purl.obolibrary.org/obo/CL_0002371) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) [1150](https://github.com/obophenotype/cell-ontology/issues/1150) + +- [obsolete somatic cell](http://purl.obolibrary.org/obo/CL_0002371) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### obsolete tertiary pigment cell `http://purl.obolibrary.org/obo/CL_0000729` +#### Removed +- [obsolete tertiary pigment cell](http://purl.obolibrary.org/obo/CL_0000729) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) "https://github.com/obophenotype/cell-ontology/issues/1930" + +#### Added +- [obsolete tertiary pigment cell](http://purl.obolibrary.org/obo/CL_0000729) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) [1930](https://github.com/obophenotype/cell-ontology/issues/1930) + + +### obsolete valve cell `http://purl.obolibrary.org/obo/CL_0000663` +#### Removed +- [obsolete valve cell](http://purl.obolibrary.org/obo/CL_0000663) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "https://github.com/obophenotype/cell-ontology/issues/726" + +#### Added +- [obsolete valve cell](http://purl.obolibrary.org/obo/CL_0000663) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) [726](https://github.com/obophenotype/cell-ontology/issues/726) + + +### occipital artery `http://purl.obolibrary.org/obo/UBERON_0001613` +#### Removed +- [occipital artery](http://purl.obolibrary.org/obo/UBERON_0001613) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria occipitalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Occipital_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [occipital artery](http://purl.obolibrary.org/obo/UBERON_0001613) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria occipitalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Occipital_artery" + + +### occipital bone `http://purl.obolibrary.org/obo/UBERON_0001676` +#### Removed +- [occipital bone](http://purl.obolibrary.org/obo/UBERON_0001676) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "os occipitale" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Occipital_bone" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [occipital bone](http://purl.obolibrary.org/obo/UBERON_0001676) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "os occipitale" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Occipital_bone" + + +### occipital region `http://purl.obolibrary.org/obo/UBERON_0005902` + +#### Added +- [occipital region](http://purl.obolibrary.org/obo/UBERON_0005902) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D009778" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [LexicalMatching](https://w3id.org/semapv/vocab/LexicalMatching) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### ocular adnexa `http://purl.obolibrary.org/obo/UBERON_0035639` +#### Removed +- [ocular adnexa](http://purl.obolibrary.org/obo/UBERON_0035639) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "adnexa oculi" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "http://medical-dictionary.thefreedictionary.com/ocular+adnexa" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [ocular adnexa](http://purl.obolibrary.org/obo/UBERON_0035639) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "structurae oculi accessoriae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Accessory_visual_structures" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [ocular adnexa](http://purl.obolibrary.org/obo/UBERON_0035639) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "structurae oculi accessoriae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Accessory_visual_structures" + +- [ocular adnexa](http://purl.obolibrary.org/obo/UBERON_0035639) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "adnexa oculi" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "http://medical-dictionary.thefreedictionary.com/ocular+adnexa" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### odontogenic papilla `http://purl.obolibrary.org/obo/UBERON_0001763` +#### Removed +- [odontogenic papilla](http://purl.obolibrary.org/obo/UBERON_0001763) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "papilla dentis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Dental_papilla" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [odontogenic papilla](http://purl.obolibrary.org/obo/UBERON_0001763) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "papilla dentis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Dental_papilla" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### olfactory bulb `http://purl.obolibrary.org/obo/UBERON_0002264` +#### Removed +- [olfactory bulb](http://purl.obolibrary.org/obo/UBERON_0002264) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "bulbus olfactorius (Morgagni)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:279" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [olfactory bulb](http://purl.obolibrary.org/obo/UBERON_0002264) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "bulbus olfactorius" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Olfactory_bulb" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [olfactory bulb](http://purl.obolibrary.org/obo/UBERON_0002264) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "bulbus olfactorius (Morgagni)" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:279" + +- [olfactory bulb](http://purl.obolibrary.org/obo/UBERON_0002264) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "bulbus olfactorius" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Olfactory_bulb" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### olfactory bulb layer `http://purl.obolibrary.org/obo/UBERON_0004001` +#### Removed +- [olfactory bulb layer](http://purl.obolibrary.org/obo/UBERON_0004001) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MP:0009946" + +#### Added +- [olfactory bulb layer](http://purl.obolibrary.org/obo/UBERON_0004001) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Missing definition for term UBERON:0004001. Please replace it using linked reference." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MP:0009946" + + +### olfactory nerve `http://purl.obolibrary.org/obo/UBERON_0001579` +#### Removed +- [olfactory nerve](http://purl.obolibrary.org/obo/UBERON_0001579) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nervus olfactorius" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0003648" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Olfactory_nerve" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [olfactory nerve](http://purl.obolibrary.org/obo/UBERON_0001579) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nervus olfactorius [i]" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:46787" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [olfactory nerve](http://purl.obolibrary.org/obo/UBERON_0001579) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nervus olfactorius" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0003648" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Olfactory_nerve" + +- [olfactory nerve](http://purl.obolibrary.org/obo/UBERON_0001579) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nervus olfactorius [i]" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:46787" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### olfactory organ `http://purl.obolibrary.org/obo/UBERON_0002268` +#### Removed +- [olfactory organ](http://purl.obolibrary.org/obo/UBERON_0002268) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005158" + +#### Added +- [olfactory organ](http://purl.obolibrary.org/obo/UBERON_0002268) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005158" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### olfactory placode `http://purl.obolibrary.org/obo/UBERON_0003050` +#### Removed +- [olfactory placode](http://purl.obolibrary.org/obo/UBERON_0003050) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "placoda nasalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [olfactory placode](http://purl.obolibrary.org/obo/UBERON_0003050) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "placoda olfactoria" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [olfactory placode](http://purl.obolibrary.org/obo/UBERON_0003050) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0006222" + - [contributor](http://purl.org/dc/terms/contributor) "https://orcid.org/0000-0003-4423-4370" + +#### Added +- [olfactory placode](http://purl.obolibrary.org/obo/UBERON_0003050) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0006222" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + - [author_id](https://w3id.org/sssom/author_id) [0000-0003-4423-4370](https://orcid.org/0000-0003-4423-4370) + +- [olfactory placode](http://purl.obolibrary.org/obo/UBERON_0003050) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "placoda olfactoria" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [olfactory placode](http://purl.obolibrary.org/obo/UBERON_0003050) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "placoda nasalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### olfactory segment of nasal mucosa `http://purl.obolibrary.org/obo/UBERON_0005386` +#### Removed +- [olfactory segment of nasal mucosa](http://purl.obolibrary.org/obo/UBERON_0005386) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pars olfactoria tunicae mucosae nasi" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:77199" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [olfactory segment of nasal mucosa](http://purl.obolibrary.org/obo/UBERON_0005386) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "pars olfactoria tunicae mucosae nasi" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Olfactory_mucosa" + +#### Added +- [olfactory segment of nasal mucosa](http://purl.obolibrary.org/obo/UBERON_0005386) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "pars olfactoria tunicae mucosae nasi" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Olfactory_mucosa" + +- [olfactory segment of nasal mucosa](http://purl.obolibrary.org/obo/UBERON_0005386) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pars olfactoria tunicae mucosae nasi" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:77199" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### olfactory tract `http://purl.obolibrary.org/obo/UBERON_0002265` +#### Removed +- [olfactory tract](http://purl.obolibrary.org/obo/UBERON_0002265) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tractus olfactorium" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:283" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [olfactory tract](http://purl.obolibrary.org/obo/UBERON_0002265) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tractus olfactorius" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Olfactory_tract" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0003647" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [olfactory tract](http://purl.obolibrary.org/obo/UBERON_0002265) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "pedunclulus olfactorius" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:283" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [olfactory tract](http://purl.obolibrary.org/obo/UBERON_0002265) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "pedunclulus olfactorius" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:283" + +- [olfactory tract](http://purl.obolibrary.org/obo/UBERON_0002265) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tractus olfactorius" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Olfactory_tract" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0003647" + +- [olfactory tract](http://purl.obolibrary.org/obo/UBERON_0002265) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tractus olfactorium" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:283" + + +### olfactory tubercle `http://purl.obolibrary.org/obo/UBERON_0001883` +#### Removed +- [olfactory tubercle](http://purl.obolibrary.org/obo/UBERON_0001883) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tuberculum olfactorium" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [olfactory tubercle](http://purl.obolibrary.org/obo/UBERON_0001883) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tuberculum olfactorium" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### oligodendrocyte `http://purl.obolibrary.org/obo/CL_0000128` + +#### Added +- [oligodendrocyte](http://purl.obolibrary.org/obo/CL_0000128) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### oligodendrocyte precursor cell `http://purl.obolibrary.org/obo/CL_0002453` + +#### Added +- [oligodendrocyte precursor cell](http://purl.obolibrary.org/obo/CL_0002453) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### ommatidium `http://purl.obolibrary.org/obo/UBERON_0000971` +#### Removed +- [ommatidium](http://purl.obolibrary.org/obo/UBERON_0000971) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00004510" + +#### Added +- [ommatidium](http://purl.obolibrary.org/obo/UBERON_0000971) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00004510" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### oocyte `http://purl.obolibrary.org/obo/CL_0000023` + +#### Added +- [oocyte](http://purl.obolibrary.org/obo/CL_0000023) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### oogonial cell `http://purl.obolibrary.org/obo/CL_0000024` + +#### Added +- [oogonial cell](http://purl.obolibrary.org/obo/CL_0000024) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### open tracheal system `http://purl.obolibrary.org/obo/UBERON_0005155` +#### Removed +- [open tracheal system](http://purl.obolibrary.org/obo/UBERON_0005155) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005024" + +#### Added +- [open tracheal system](http://purl.obolibrary.org/obo/UBERON_0005155) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005024" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### ophthalmic artery `http://purl.obolibrary.org/obo/UBERON_0001619` +#### Removed +- [ophthalmic artery](http://purl.obolibrary.org/obo/UBERON_0001619) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria ophthalmica" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Ophthalmic_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [ophthalmic artery](http://purl.obolibrary.org/obo/UBERON_0001619) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria ophthalmica" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Ophthalmic_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### ophthalmic nerve `http://purl.obolibrary.org/obo/UBERON_0000348` +#### Removed +- [ophthalmic nerve](http://purl.obolibrary.org/obo/UBERON_0000348) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nervus ophthalmicus [va]" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:52621" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [ophthalmic nerve](http://purl.obolibrary.org/obo/UBERON_0000348) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nervus ophthalmicus [v1]" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:52621" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [ophthalmic nerve](http://purl.obolibrary.org/obo/UBERON_0000348) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nervus ophthalmicus [v1]" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:52621" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [ophthalmic nerve](http://purl.obolibrary.org/obo/UBERON_0000348) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nervus ophthalmicus [va]" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:52621" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### optic chiasma `http://purl.obolibrary.org/obo/UBERON_0000959` +#### Removed +- [optic chiasma](http://purl.obolibrary.org/obo/UBERON_0000959) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "chiasma opticum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Optic_chiasm" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [optic chiasma](http://purl.obolibrary.org/obo/UBERON_0000959) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "chiasma" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:459" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [optic chiasma](http://purl.obolibrary.org/obo/UBERON_0000959) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "chiasma nervorum opticorum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:459" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [optic chiasma](http://purl.obolibrary.org/obo/UBERON_0000959) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "chiasma nervorum opticorum" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:459" + +- [optic chiasma](http://purl.obolibrary.org/obo/UBERON_0000959) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "chiasma" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:459" + +- [optic chiasma](http://purl.obolibrary.org/obo/UBERON_0000959) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "chiasma opticum" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Optic_chiasm" + + +### optic choroid `http://purl.obolibrary.org/obo/UBERON_0001776` +#### Removed +- [optic choroid](http://purl.obolibrary.org/obo/UBERON_0001776) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "choroidea" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Choroid" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [optic choroid](http://purl.obolibrary.org/obo/UBERON_0001776) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "choroidea" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Choroid" + + +### optic foramen `http://purl.obolibrary.org/obo/UBERON_0005745` +#### Removed +- [optic foramen](http://purl.obolibrary.org/obo/UBERON_0005745) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "foramen opticum ossis sphenoidalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Optic_canal" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [optic foramen](http://purl.obolibrary.org/obo/UBERON_0005745) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "canalis opticus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Optic_canal" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [optic foramen](http://purl.obolibrary.org/obo/UBERON_0005745) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "foramen opticum ossis sphenoidalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Optic_canal" + +- [optic foramen](http://purl.obolibrary.org/obo/UBERON_0005745) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "canalis opticus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Optic_canal" + + +### optic stalk `http://purl.obolibrary.org/obo/UBERON_0003098` +#### Removed +- [optic stalk](http://purl.obolibrary.org/obo/UBERON_0003098) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "pedunculus opticus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Optic_stalk" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [optic stalk](http://purl.obolibrary.org/obo/UBERON_0003098) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "pedunculus opticus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Optic_stalk" + + +### optic tract `http://purl.obolibrary.org/obo/UBERON_0001908` +#### Removed +- [optic tract](http://purl.obolibrary.org/obo/UBERON_0001908) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tractus opticus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Optic_tract" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [optic tract](http://purl.obolibrary.org/obo/UBERON_0001908) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tractus optici" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:460" + +#### Added +- [optic tract](http://purl.obolibrary.org/obo/UBERON_0001908) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tractus optici" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:460" + +- [optic tract](http://purl.obolibrary.org/obo/UBERON_0001908) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tractus opticus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Optic_tract" + + +### oral cavity `http://purl.obolibrary.org/obo/UBERON_0000167` + +#### Added +- [oral cavity](http://purl.obolibrary.org/obo/UBERON_0000167) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D009055" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [LexicalMatching](https://w3id.org/semapv/vocab/LexicalMatching) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### orbitosphenoid `http://purl.obolibrary.org/obo/UBERON_0002478` +#### Removed +- [orbitosphenoid](http://purl.obolibrary.org/obo/UBERON_0002478) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ala minor ossis sphenoidalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:52869" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [orbitosphenoid](http://purl.obolibrary.org/obo/UBERON_0002478) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "alae parvae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Lesser_wing_of_sphenoid_bone" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [orbitosphenoid](http://purl.obolibrary.org/obo/UBERON_0002478) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ala minor ossis sphenoidalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:52869" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [orbitosphenoid](http://purl.obolibrary.org/obo/UBERON_0002478) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "alae parvae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Lesser_wing_of_sphenoid_bone" + + +### organ system subdivision `http://purl.obolibrary.org/obo/UBERON_0011216` +#### Removed +- [organ system subdivision](http://purl.obolibrary.org/obo/UBERON_0011216) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007330" + +#### Added +- [organ system subdivision](http://purl.obolibrary.org/obo/UBERON_0011216) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007330" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + +- [organ system subdivision](http://purl.obolibrary.org/obo/UBERON_0011216) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606) + +- [organ system subdivision](http://purl.obolibrary.org/obo/UBERON_0011216) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [human_reference_atlas](http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas) + + +### organelle `http://purl.obolibrary.org/obo/GO_0043226` +#### Removed +- [organelle](http://purl.obolibrary.org/obo/GO_0043226) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [prokaryote_subset](http://purl.obolibrary.org/obo/go#prokaryote_subset) + +#### Added +- [organelle](http://purl.obolibrary.org/obo/GO_0043226) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_prokaryote](http://purl.obolibrary.org/obo/go#goslim_prokaryote) + + +### organic substance metabolic process `http://purl.obolibrary.org/obo/GO_0071704` + +#### Added +- [organic substance metabolic process](http://purl.obolibrary.org/obo/GO_0071704) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [gocheck_do_not_annotate](http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate) + +- [organic substance metabolic process](http://purl.obolibrary.org/obo/GO_0071704) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) "https://github.com/geneontology/go-ontology/issues/26424"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + + +### organism subdivision `http://purl.obolibrary.org/obo/UBERON_0000475` +#### Removed +- [organism subdivision](http://purl.obolibrary.org/obo/UBERON_0000475) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007009" + +#### Added +- [organism subdivision](http://purl.obolibrary.org/obo/UBERON_0000475) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007009" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### organism substance `http://purl.obolibrary.org/obo/UBERON_0000463` +#### Removed +- [organism substance](http://purl.obolibrary.org/obo/UBERON_0000463) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007019" + +#### Added +- [organism substance](http://purl.obolibrary.org/obo/UBERON_0000463) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007019" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### organonitrogen compound metabolic process `http://purl.obolibrary.org/obo/GO_1901564` + +#### Added +- [organonitrogen compound metabolic process](http://purl.obolibrary.org/obo/GO_1901564) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) "https://github.com/geneontology/go-ontology/issues/26424"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + +- [organonitrogen compound metabolic process](http://purl.obolibrary.org/obo/GO_1901564) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [gocheck_do_not_annotate](http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate) + + +### ossification center `http://purl.obolibrary.org/obo/UBERON_0010355` +#### Removed +- [ossification center](http://purl.obolibrary.org/obo/UBERON_0010355) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "centrum ossificationis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [ossification center](http://purl.obolibrary.org/obo/UBERON_0010355) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "centrum ossificationis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Ossification_center" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [ossification center](http://purl.obolibrary.org/obo/UBERON_0010355) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "centrum ossificationis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [ossification center](http://purl.obolibrary.org/obo/UBERON_0010355) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "centrum ossificationis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Ossification_center" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### osteoblast `http://purl.obolibrary.org/obo/CL_0000062` + +#### Added +- [osteoblast](http://purl.obolibrary.org/obo/CL_0000062) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### osteoclast `http://purl.obolibrary.org/obo/CL_0000092` + +#### Added +- [osteoclast](http://purl.obolibrary.org/obo/CL_0000092) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### otic capsule `http://purl.obolibrary.org/obo/UBERON_0004637` +#### Removed +- [otic capsule](http://purl.obolibrary.org/obo/UBERON_0004637) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0005981" + - [contributor](http://purl.org/dc/terms/contributor) "https://orcid.org/0000-0003-4423-4370" + +#### Added +- [otic capsule](http://purl.obolibrary.org/obo/UBERON_0004637) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0005981" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + - [author_id](https://w3id.org/sssom/author_id) [0000-0003-4423-4370](https://orcid.org/0000-0003-4423-4370) + + +### otic placode `http://purl.obolibrary.org/obo/UBERON_0003069` +#### Removed +- [otic placode](http://purl.obolibrary.org/obo/UBERON_0003069) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "placoda otica" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [otic placode](http://purl.obolibrary.org/obo/UBERON_0003069) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "placoda otica" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### outer epithelium `http://purl.obolibrary.org/obo/UBERON_0007376` +#### Removed +- [outer epithelium](http://purl.obolibrary.org/obo/UBERON_0007376) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00004993" + +#### Added +- [outer epithelium](http://purl.obolibrary.org/obo/UBERON_0007376) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00004993" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### outer limiting layer of retina `http://purl.obolibrary.org/obo/UBERON_0001788` +#### Removed +- [outer limiting layer of retina](http://purl.obolibrary.org/obo/UBERON_0001788) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "stratum limitans externum retinae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:58683" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [outer limiting layer of retina](http://purl.obolibrary.org/obo/UBERON_0001788) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "stratum limitans externum retinae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:58683" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### outer medulla of kidney `http://purl.obolibrary.org/obo/UBERON_0001293` +#### Removed +- [outer medulla of kidney](http://purl.obolibrary.org/obo/UBERON_0001293) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "zona externa medullae renalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:17733" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [outer medulla of kidney](http://purl.obolibrary.org/obo/UBERON_0001293) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "zona externa (medullaris renalis)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:17733" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [outer medulla of kidney](http://purl.obolibrary.org/obo/UBERON_0001293) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "zona externa (medullaris renalis)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:17733" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [outer medulla of kidney](http://purl.obolibrary.org/obo/UBERON_0001293) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "zona externa medullae renalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:17733" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### outer nuclear layer of retina `http://purl.obolibrary.org/obo/UBERON_0001789` +#### Removed +- [outer nuclear layer of retina](http://purl.obolibrary.org/obo/UBERON_0001789) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "stratum nucleare externum retinae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:58684" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [outer nuclear layer of retina](http://purl.obolibrary.org/obo/UBERON_0001789) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "stratum nucleare externum retinae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:58684" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### outer plexiform layer of retina `http://purl.obolibrary.org/obo/UBERON_0001790` +#### Removed +- [outer plexiform layer of retina](http://purl.obolibrary.org/obo/UBERON_0001790) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "stratum plexiforme externum retinae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:58685" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [outer plexiform layer of retina](http://purl.obolibrary.org/obo/UBERON_0001790) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "stratum plexiforme externum retinae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:58685" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### outflow part of left ventricle `http://purl.obolibrary.org/obo/UBERON_0005956` +#### Removed +- [outflow part of left ventricle](http://purl.obolibrary.org/obo/UBERON_0005956) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "vestibulum aortae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:9473" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [outflow part of left ventricle](http://purl.obolibrary.org/obo/UBERON_0005956) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "vestibulum aortae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:9473" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### ovarian artery `http://purl.obolibrary.org/obo/UBERON_0001190` +#### Removed +- [ovarian artery](http://purl.obolibrary.org/obo/UBERON_0001190) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria ovarica" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Ovarian_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [ovarian artery](http://purl.obolibrary.org/obo/UBERON_0001190) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria ovarica" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Ovarian_artery" + + +### ovarian follicle `http://purl.obolibrary.org/obo/UBERON_0001305` +#### Removed +- [ovarian follicle](http://purl.obolibrary.org/obo/UBERON_0001305) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "folliculi ovarici primarii" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Ovarian_follicle" + +- [ovarian follicle](http://purl.obolibrary.org/obo/UBERON_0001305) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "folliculi ovarici vesiculosi" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Ovarian_follicle" + +#### Added +- [ovarian follicle](http://purl.obolibrary.org/obo/UBERON_0001305) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "folliculi ovarici vesiculosi" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Ovarian_follicle" + +- [ovarian follicle](http://purl.obolibrary.org/obo/UBERON_0001305) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "folliculi ovarici primarii" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Ovarian_follicle" + + +### ovarian nurse cell to oocyte transport `http://purl.obolibrary.org/obo/GO_0007300` +#### Removed +- [ovarian nurse cell to oocyte transport](http://purl.obolibrary.org/obo/GO_0007300) [has_broad_synonym](http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym) "nurse cell to oocyte transport" + +- [ovarian nurse cell to oocyte transport](http://purl.obolibrary.org/obo/GO_0007300) [label](http://www.w3.org/2000/01/rdf-schema#label) "ovarian nurse cell to oocyte transport" + +- [ovarian nurse cell to oocyte transport](http://purl.obolibrary.org/obo/GO_0007300) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0007300" + +- [ovarian nurse cell to oocyte transport](http://purl.obolibrary.org/obo/GO_0007300) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [ovarian nurse cell to oocyte transport](http://purl.obolibrary.org/obo/GO_0007300) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Transfer of constituents synthesized in the ovarian nurse cells to the oocyte, through the ring canals, as the egg chamber is growing. An example of this is found in Drosophila melanogaster." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mtg_sensu" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0879694238" + +- Class: [ovarian nurse cell to oocyte transport](http://purl.obolibrary.org/obo/GO_0007300) + +- [ovarian nurse cell to oocyte transport](http://purl.obolibrary.org/obo/GO_0007300) EquivalentTo [transport](http://purl.obolibrary.org/obo/GO_0006810) and ([has target start location](http://purl.obolibrary.org/obo/RO_0002338) some [invertebrate nurse cell](http://purl.obolibrary.org/obo/CL_0000026)) and ([has target end location](http://purl.obolibrary.org/obo/RO_0002339) some [oocyte](http://purl.obolibrary.org/obo/CL_0000023)) and ([results in transport along](http://purl.obolibrary.org/obo/RO_0002341) some [germline ring canal](http://purl.obolibrary.org/obo/GO_0045172)) + +- [ovarian nurse cell to oocyte transport](http://purl.obolibrary.org/obo/GO_0007300) SubClassOf [results in transport along](http://purl.obolibrary.org/obo/RO_0002341) some [germline ring canal](http://purl.obolibrary.org/obo/GO_0045172) + +- [ovarian nurse cell to oocyte transport](http://purl.obolibrary.org/obo/GO_0007300) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [oogenesis](http://purl.obolibrary.org/obo/GO_0048477) + +- [ovarian nurse cell to oocyte transport](http://purl.obolibrary.org/obo/GO_0007300) SubClassOf [has target start location](http://purl.obolibrary.org/obo/RO_0002338) some [invertebrate nurse cell](http://purl.obolibrary.org/obo/CL_0000026) + +- [ovarian nurse cell to oocyte transport](http://purl.obolibrary.org/obo/GO_0007300) SubClassOf [only in taxon](http://purl.obolibrary.org/obo/RO_0002160) some [Insecta](http://purl.obolibrary.org/obo/NCBITaxon_50557) + +- [ovarian nurse cell to oocyte transport](http://purl.obolibrary.org/obo/GO_0007300) SubClassOf [in taxon](http://purl.obolibrary.org/obo/RO_0002162) only [Insecta](http://purl.obolibrary.org/obo/NCBITaxon_50557) + +- [ovarian nurse cell to oocyte transport](http://purl.obolibrary.org/obo/GO_0007300) SubClassOf [has target end location](http://purl.obolibrary.org/obo/RO_0002339) some [oocyte](http://purl.obolibrary.org/obo/CL_0000023) + +- [ovarian nurse cell to oocyte transport](http://purl.obolibrary.org/obo/GO_0007300) SubClassOf [reproductive process](http://purl.obolibrary.org/obo/GO_0022414) + +- [ovarian nurse cell to oocyte transport](http://purl.obolibrary.org/obo/GO_0007300) SubClassOf [transport](http://purl.obolibrary.org/obo/GO_0006810) + + + +### ovarian surface epithelial cell `http://purl.obolibrary.org/obo/CL_2000064` + +#### Added +- [ovarian surface epithelial cell](http://purl.obolibrary.org/obo/CL_2000064) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### ovarian vein `http://purl.obolibrary.org/obo/UBERON_0001145` +#### Removed +- [ovarian vein](http://purl.obolibrary.org/obo/UBERON_0001145) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vena ovarica sinistra" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Ovarian_vein" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [ovarian vein](http://purl.obolibrary.org/obo/UBERON_0001145) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vena ovarica dextra" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Ovarian_vein" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [ovarian vein](http://purl.obolibrary.org/obo/UBERON_0001145) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vena ovarica sinistra" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Ovarian_vein" + +- [ovarian vein](http://purl.obolibrary.org/obo/UBERON_0001145) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vena ovarica dextra" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Ovarian_vein" + + +### ovary `http://purl.obolibrary.org/obo/UBERON_0000992` +#### Removed +- [ovary](http://purl.obolibrary.org/obo/UBERON_0000992) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00004865" + +- [ovary](http://purl.obolibrary.org/obo/UBERON_0000992) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ovarium" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Ovary" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [ovary](http://purl.obolibrary.org/obo/UBERON_0000992) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00004865" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + +- [ovary](http://purl.obolibrary.org/obo/UBERON_0000992) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ovarium" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Ovary" + + +### ovary stroma `http://purl.obolibrary.org/obo/UBERON_0006960` +#### Removed +- [ovary stroma](http://purl.obolibrary.org/obo/UBERON_0006960) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "stroma ovarii" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Stroma_of_ovary" + +#### Added +- [ovary stroma](http://purl.obolibrary.org/obo/UBERON_0006960) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "stroma ovarii" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Stroma_of_ovary" + + +### pair of dorsal aortae `http://purl.obolibrary.org/obo/UBERON_0010190` + +#### Added +- [pair of dorsal aortae](http://purl.obolibrary.org/obo/UBERON_0010190) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MA:0000476" + +- [pair of dorsal aortae](http://purl.obolibrary.org/obo/UBERON_0010190) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "uberon" + +- [pair of dorsal aortae](http://purl.obolibrary.org/obo/UBERON_0010190) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "paired dorsal aortae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "EHDAA2:0000410" + +- [pair of dorsal aortae](http://purl.obolibrary.org/obo/UBERON_0010190) [label](http://www.w3.org/2000/01/rdf-schema#label) "pair of dorsal aortae" + +- [pair of dorsal aortae](http://purl.obolibrary.org/obo/UBERON_0010190) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "EHDAA2:0000410" + +- [pair of dorsal aortae](http://purl.obolibrary.org/obo/UBERON_0010190) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [pheno_slim](http://purl.obolibrary.org/obo/uberon/core#pheno_slim) + +- [pair of dorsal aortae](http://purl.obolibrary.org/obo/UBERON_0010190) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The paired arterial structures of the embryo that supplies each developing somite via efferent segmental arteries; the dorsal aortae articulate with the umbilical arteries, which return mixed blood to the villi of the chorion for reoxygenation." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MP:0004787" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0-914294-08-3" + +- [pair of dorsal aortae](http://purl.obolibrary.org/obo/UBERON_0010190) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "EMAPA:18606" + +- [pair of dorsal aortae](http://purl.obolibrary.org/obo/UBERON_0010190) [id](http://www.geneontology.org/formats/oboInOwl#id) "UBERON:0010190" + +- Class: [pair of dorsal aortae](http://purl.obolibrary.org/obo/UBERON_0010190) + +- [pair of dorsal aortae](http://purl.obolibrary.org/obo/UBERON_0010190) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [dorsal aorta](http://purl.obolibrary.org/obo/UBERON_0005805) + +- [pair of dorsal aortae](http://purl.obolibrary.org/obo/UBERON_0010190) SubClassOf [protein-containing material entity](http://purl.obolibrary.org/obo/PR_000050567) + +- [pair of dorsal aortae](http://purl.obolibrary.org/obo/UBERON_0010190) SubClassOf [multi-tissue structure](http://purl.obolibrary.org/obo/UBERON_0000481) + - [source](http://www.geneontology.org/formats/oboInOwl#source) "EHDAA2" + +- [pair of dorsal aortae](http://purl.obolibrary.org/obo/UBERON_0010190) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [aortic system](http://purl.obolibrary.org/obo/UBERON_0010191) + - [source](http://www.geneontology.org/formats/oboInOwl#source) "EHDAA2" + + +### pair of lungs `http://purl.obolibrary.org/obo/UBERON_0000170` +#### Removed +- [pair of lungs](http://purl.obolibrary.org/obo/UBERON_0000170) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pulmones" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:68877" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [pair of lungs](http://purl.obolibrary.org/obo/UBERON_0000170) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [human_reference_atlas](http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas) + +- [pair of lungs](http://purl.obolibrary.org/obo/UBERON_0000170) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606) + +- [pair of lungs](http://purl.obolibrary.org/obo/UBERON_0000170) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pulmones" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:68877" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### palpebral vein `http://purl.obolibrary.org/obo/UBERON_0014769` +#### Removed +- [palpebral vein](http://purl.obolibrary.org/obo/UBERON_0014769) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "venae palpebrales" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [palpebral vein](http://purl.obolibrary.org/obo/UBERON_0014769) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "venae palpebrales" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### pampiniform plexus `http://purl.obolibrary.org/obo/UBERON_0001330` +#### Removed +- [pampiniform plexus](http://purl.obolibrary.org/obo/UBERON_0001330) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "plexus venosus pampiniformis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:19607" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [pampiniform plexus](http://purl.obolibrary.org/obo/UBERON_0001330) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "plexus venosus pampiniformis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:19607" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### panarthropod head `http://purl.obolibrary.org/obo/UBERON_6000004` +#### Removed +- [panarthropod head](http://purl.obolibrary.org/obo/UBERON_6000004) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00000004" + +#### Added +- [panarthropod head](http://purl.obolibrary.org/obo/UBERON_6000004) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00000004" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### pancreatic A cell `http://purl.obolibrary.org/obo/CL_0000171` + +#### Added +- [pancreatic A cell](http://purl.obolibrary.org/obo/CL_0000171) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### pancreatic D cell `http://purl.obolibrary.org/obo/CL_0000173` + +#### Added +- [pancreatic D cell](http://purl.obolibrary.org/obo/CL_0000173) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### pancreatic PP cell `http://purl.obolibrary.org/obo/CL_0002275` + +#### Added +- [pancreatic PP cell](http://purl.obolibrary.org/obo/CL_0002275) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### pancreatic acinar cell `http://purl.obolibrary.org/obo/CL_0002064` + +#### Added +- [pancreatic acinar cell](http://purl.obolibrary.org/obo/CL_0002064) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### pancreatic acinus `http://purl.obolibrary.org/obo/UBERON_0001263` +#### Removed +- [pancreatic acinus](http://purl.obolibrary.org/obo/UBERON_0001263) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "acinus pancreaticus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:16011" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [pancreatic acinus](http://purl.obolibrary.org/obo/UBERON_0001263) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0000028" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + - [author_id](https://w3id.org/sssom/author_id) [0000-0003-4423-4370](https://orcid.org/0000-0003-4423-4370) + +- [pancreatic acinus](http://purl.obolibrary.org/obo/UBERON_0001263) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "acinus pancreaticus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:16011" + + +### pancreatic duct `http://purl.obolibrary.org/obo/UBERON_0007329` +#### Removed +- [pancreatic duct](http://purl.obolibrary.org/obo/UBERON_0007329) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D010183" + +- [pancreatic duct](http://purl.obolibrary.org/obo/UBERON_0007329) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ductus pancreaticus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Pancreatic_duct" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [pancreatic duct](http://purl.obolibrary.org/obo/UBERON_0007329) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D010183" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [author_id](https://w3id.org/sssom/author_id) [0000-0001-9439-5346](https://orcid.org/0000-0001-9439-5346) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + +- [pancreatic duct](http://purl.obolibrary.org/obo/UBERON_0007329) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ductus pancreaticus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Pancreatic_duct" + + +### pancreatic ductal cell `http://purl.obolibrary.org/obo/CL_0002079` + +#### Added +- [pancreatic ductal cell](http://purl.obolibrary.org/obo/CL_0002079) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### pancreatic endocrine cell `http://purl.obolibrary.org/obo/CL_0008024` + +#### Added +- [pancreatic endocrine cell](http://purl.obolibrary.org/obo/CL_0008024) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### pancreatic epsilon cell `http://purl.obolibrary.org/obo/CL_0005019` + +#### Added +- [pancreatic epsilon cell](http://purl.obolibrary.org/obo/CL_0005019) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### pancreatic stellate cell `http://purl.obolibrary.org/obo/CL_0002410` + +#### Added +- [pancreatic stellate cell](http://purl.obolibrary.org/obo/CL_0002410) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### paneth cell `http://purl.obolibrary.org/obo/CL_0000510` + +#### Added +- [paneth cell](http://purl.obolibrary.org/obo/CL_0000510) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### paneth cell of colon `http://purl.obolibrary.org/obo/CL_0009009` + +#### Added +- [paneth cell of colon](http://purl.obolibrary.org/obo/CL_0009009) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### paneth cell of epithelium of small intestine `http://purl.obolibrary.org/obo/CL_1000343` + +#### Added +- [paneth cell of epithelium of small intestine](http://purl.obolibrary.org/obo/CL_1000343) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### papillary layer of dermis `http://purl.obolibrary.org/obo/UBERON_0001992` +#### Removed +- [papillary layer of dermis](http://purl.obolibrary.org/obo/UBERON_0001992) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "stratum papillare dermis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:64776" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [papillary layer of dermis](http://purl.obolibrary.org/obo/UBERON_0001992) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "stratum papillare (dermis)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:64776" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [papillary layer of dermis](http://purl.obolibrary.org/obo/UBERON_0001992) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "stratum papillare" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Papillary_dermis" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [papillary layer of dermis](http://purl.obolibrary.org/obo/UBERON_0001992) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "stratum papillare (dermis)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:64776" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [papillary layer of dermis](http://purl.obolibrary.org/obo/UBERON_0001992) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "stratum papillare dermis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:64776" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [papillary layer of dermis](http://purl.obolibrary.org/obo/UBERON_0001992) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "stratum papillare" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Papillary_dermis" + + +### papillary tips cell `http://purl.obolibrary.org/obo/CL_1000597` + +#### Added +- [papillary tips cell](http://purl.obolibrary.org/obo/CL_1000597) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### parasympathetic ganglion `http://purl.obolibrary.org/obo/UBERON_0001808` +#### Removed +- [parasympathetic ganglion](http://purl.obolibrary.org/obo/UBERON_0001808) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D005726" + +- [parasympathetic ganglion](http://purl.obolibrary.org/obo/UBERON_0001808) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ganglion parasympathicum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0001256" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Parasympathetic_ganglion" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [parasympathetic ganglion](http://purl.obolibrary.org/obo/UBERON_0001808) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ganglion parasympathicum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0001256" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Parasympathetic_ganglion" + +- [parasympathetic ganglion](http://purl.obolibrary.org/obo/UBERON_0001808) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D005726" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [author_id](https://w3id.org/sssom/author_id) [0000-0001-9439-5346](https://orcid.org/0000-0001-9439-5346) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### parasympathetic nervous system `http://purl.obolibrary.org/obo/UBERON_0000011` +#### Removed +- [parasympathetic nervous system](http://purl.obolibrary.org/obo/UBERON_0000011) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pars parasympathica divisionis autonomici systematis nervosi" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:9907" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [parasympathetic nervous system](http://purl.obolibrary.org/obo/UBERON_0000011) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "pars parasympathica divisionis autonomici systematis nervosi" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Parasympathetic_nervous_system" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [parasympathetic nervous system](http://purl.obolibrary.org/obo/UBERON_0000011) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "pars parasympathica divisionis autonomici systematis nervosi" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Parasympathetic_nervous_system" + +- [parasympathetic nervous system](http://purl.obolibrary.org/obo/UBERON_0000011) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pars parasympathica divisionis autonomici systematis nervosi" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:9907" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### paraventricular nucleus of hypothalamus `http://purl.obolibrary.org/obo/UBERON_0001930` +#### Removed +- [paraventricular nucleus of hypothalamus](http://purl.obolibrary.org/obo/UBERON_0001930) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nuclei paraventriculares" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:387" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [paraventricular nucleus of hypothalamus](http://purl.obolibrary.org/obo/UBERON_0001930) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus hypothalami paraventricularis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:387" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [paraventricular nucleus of hypothalamus](http://purl.obolibrary.org/obo/UBERON_0001930) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus hypothalami filiformis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:387" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [paraventricular nucleus of hypothalamus](http://purl.obolibrary.org/obo/UBERON_0001930) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nuclei paraventricularis hypothalami" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Paraventricular_nucleus_of_hypothalamus" + +- [paraventricular nucleus of hypothalamus](http://purl.obolibrary.org/obo/UBERON_0001930) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus filiformis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:387" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [paraventricular nucleus of hypothalamus](http://purl.obolibrary.org/obo/UBERON_0001930) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus filiformis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:387" + +- [paraventricular nucleus of hypothalamus](http://purl.obolibrary.org/obo/UBERON_0001930) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nuclei paraventricularis hypothalami" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Paraventricular_nucleus_of_hypothalamus" + +- [paraventricular nucleus of hypothalamus](http://purl.obolibrary.org/obo/UBERON_0001930) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus hypothalami filiformis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:387" + +- [paraventricular nucleus of hypothalamus](http://purl.obolibrary.org/obo/UBERON_0001930) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nuclei paraventriculares" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:387" + +- [paraventricular nucleus of hypothalamus](http://purl.obolibrary.org/obo/UBERON_0001930) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus hypothalami paraventricularis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:387" + + +### paravertebral ganglion `http://purl.obolibrary.org/obo/UBERON_0001807` +#### Removed +- [paravertebral ganglion](http://purl.obolibrary.org/obo/UBERON_0001807) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ganglia trunci sympathici" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Paravertebral_ganglia" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [paravertebral ganglion](http://purl.obolibrary.org/obo/UBERON_0001807) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ganglion trunci sympathici" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:5891" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [paravertebral ganglion](http://purl.obolibrary.org/obo/UBERON_0001807) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ganglion trunci sympathetici" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [paravertebral ganglion](http://purl.obolibrary.org/obo/UBERON_0001807) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ganglion trunci sympathetici" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [paravertebral ganglion](http://purl.obolibrary.org/obo/UBERON_0001807) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ganglion trunci sympathici" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:5891" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [paravertebral ganglion](http://purl.obolibrary.org/obo/UBERON_0001807) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ganglia trunci sympathici" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Paravertebral_ganglia" + + +### paraxial mesoderm `http://purl.obolibrary.org/obo/UBERON_0003077` +#### Removed +- [paraxial mesoderm](http://purl.obolibrary.org/obo/UBERON_0003077) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "mesoderma paraxiale" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Paraxial_mesoderm" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [paraxial mesoderm](http://purl.obolibrary.org/obo/UBERON_0003077) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "mesoderma paraxiale" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Paraxial_mesoderm" + + +### parenchyma `http://purl.obolibrary.org/obo/UBERON_0000353` +#### Removed +- [parenchyma](http://purl.obolibrary.org/obo/UBERON_0000353) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0001539" + - [contributor](http://purl.org/dc/terms/contributor) "https://orcid.org/0000-0003-4423-4370" + +#### Added +- [parenchyma](http://purl.obolibrary.org/obo/UBERON_0000353) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0001539" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + - [author_id](https://w3id.org/sssom/author_id) [0000-0003-4423-4370](https://orcid.org/0000-0003-4423-4370) + +- [parenchyma](http://purl.obolibrary.org/obo/UBERON_0000353) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0000999" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + - [author_id](https://w3id.org/sssom/author_id) [0000-0003-4423-4370](https://orcid.org/0000-0003-4423-4370) + + +### parietal cell `http://purl.obolibrary.org/obo/CL_0000162` + +#### Added +- [parietal cell](http://purl.obolibrary.org/obo/CL_0000162) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### parietal cortex `http://purl.obolibrary.org/obo/UBERON_0016530` + +#### Added +- [parietal cortex](http://purl.obolibrary.org/obo/UBERON_0016530) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D010296" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [LexicalMatching](https://w3id.org/semapv/vocab/LexicalMatching) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### parietal epithelial cell `http://purl.obolibrary.org/obo/CL_1000452` + +#### Added +- [parietal epithelial cell](http://purl.obolibrary.org/obo/CL_1000452) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### parietal lobe `http://purl.obolibrary.org/obo/UBERON_0001872` +#### Removed +- [parietal lobe](http://purl.obolibrary.org/obo/UBERON_0001872) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regio parietalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:61826" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [parietal lobe](http://purl.obolibrary.org/obo/UBERON_0001872) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "lobus parietalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Parietal_lobe" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [parietal lobe](http://purl.obolibrary.org/obo/UBERON_0001872) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regio parietalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:61826" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [parietal lobe](http://purl.obolibrary.org/obo/UBERON_0001872) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "lobus parietalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Parietal_lobe" + + +### parietal pleura `http://purl.obolibrary.org/obo/UBERON_0002400` +#### Removed +- [parietal pleura](http://purl.obolibrary.org/obo/UBERON_0002400) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "pleura parietalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Parietal_pleura" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [parietal pleura](http://purl.obolibrary.org/obo/UBERON_0002400) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "pleura parietalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Parietal_pleura" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### parietal serous pericardium `http://purl.obolibrary.org/obo/UBERON_0002408` +#### Removed +- [parietal serous pericardium](http://purl.obolibrary.org/obo/UBERON_0002408) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lamina parietalis pericardii" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:9870" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [parietal serous pericardium](http://purl.obolibrary.org/obo/UBERON_0002408) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lamina parietalis pericardii" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:9870" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### pars distalis of adenohypophysis `http://purl.obolibrary.org/obo/UBERON_0006964` +#### Removed +- [pars distalis of adenohypophysis](http://purl.obolibrary.org/obo/UBERON_0006964) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pars distalis adenohypophysis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:74630" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [pars distalis of adenohypophysis](http://purl.obolibrary.org/obo/UBERON_0006964) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "pars distalis (hypophysis)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:410" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [pars distalis of adenohypophysis](http://purl.obolibrary.org/obo/UBERON_0006964) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pars distalis (glandula pituitaria)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:74630" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [pars distalis of adenohypophysis](http://purl.obolibrary.org/obo/UBERON_0006964) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pars distalis adenohypophysis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:74630" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [pars distalis of adenohypophysis](http://purl.obolibrary.org/obo/UBERON_0006964) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "pars distalis (hypophysis)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:410" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [pars distalis of adenohypophysis](http://purl.obolibrary.org/obo/UBERON_0006964) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pars distalis (glandula pituitaria)" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:74630" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### parvocellular layer of dorsal nucleus of lateral geniculate body `http://purl.obolibrary.org/obo/UBERON_0013607` +#### Removed +- [parvocellular layer of dorsal nucleus of lateral geniculate body](http://purl.obolibrary.org/obo/UBERON_0013607) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "strata parvocellularia nuclei dorsalis corporis geniculati lateralis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:76992" + +#### Added +- [parvocellular layer of dorsal nucleus of lateral geniculate body](http://purl.obolibrary.org/obo/UBERON_0013607) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "strata parvocellularia nuclei dorsalis corporis geniculati lateralis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:76992" + + +### patella `http://purl.obolibrary.org/obo/UBERON_0002446` +#### Removed +- [patella](http://purl.obolibrary.org/obo/UBERON_0002446) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "patella" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Patella" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [patella](http://purl.obolibrary.org/obo/UBERON_0002446) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "patella" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Patella" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### pectinate line `http://purl.obolibrary.org/obo/UBERON_0006574` +#### Removed +- [pectinate line](http://purl.obolibrary.org/obo/UBERON_0006574) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "linea pectinata canalis analis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:75383" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [pectinate line](http://purl.obolibrary.org/obo/UBERON_0006574) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "linea anocutanea" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Pectinate_line" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [pectinate line](http://purl.obolibrary.org/obo/UBERON_0006574) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "linea pectinata canalis analis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:75383" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [pectinate line](http://purl.obolibrary.org/obo/UBERON_0006574) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "linea anocutanea" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Pectinate_line" + + +### pectoral girdle region `http://purl.obolibrary.org/obo/UBERON_0001421` +#### Removed +- [pectoral girdle region](http://purl.obolibrary.org/obo/UBERON_0001421) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cingulum membri superioris" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:23217" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [pectoral girdle region](http://purl.obolibrary.org/obo/UBERON_0001421) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cingulum membri superioris" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:23217" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### pectoral girdle skeleton `http://purl.obolibrary.org/obo/UBERON_0007831` +#### Removed +- [pectoral girdle skeleton](http://purl.obolibrary.org/obo/UBERON_0007831) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cingulum pectorale" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Pectoral_girdle" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [pectoral girdle skeleton](http://purl.obolibrary.org/obo/UBERON_0007831) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cingulum pectorale" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Pectoral_girdle" + + +### pectoralis major `http://purl.obolibrary.org/obo/UBERON_0002381` +#### Removed +- [pectoralis major](http://purl.obolibrary.org/obo/UBERON_0002381) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "musculus pectoralis major" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Pectoralis_major_muscle" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [pectoralis major](http://purl.obolibrary.org/obo/UBERON_0002381) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "musculus pectoralis major" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Pectoralis_major_muscle" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### pectoralis minor `http://purl.obolibrary.org/obo/UBERON_0001100` +#### Removed +- [pectoralis minor](http://purl.obolibrary.org/obo/UBERON_0001100) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "musculus pectoralis minor" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Pectoralis_minor_muscle" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [pectoralis minor](http://purl.obolibrary.org/obo/UBERON_0001100) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "musculus pectoralis minor" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Pectoralis_minor_muscle" + + +### pedal digit `http://purl.obolibrary.org/obo/UBERON_0001466` +#### Removed +- [pedal digit](http://purl.obolibrary.org/obo/UBERON_0001466) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "digiti pedis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Toe" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [pedal digit](http://purl.obolibrary.org/obo/UBERON_0001466) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "digiti pedis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Toe" + + +### pelvic cavity `http://purl.obolibrary.org/obo/UBERON_0008203` +#### Removed +- [pelvic cavity](http://purl.obolibrary.org/obo/UBERON_0008203) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cavitas pelvis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Pelvic_cavity" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [pelvic cavity](http://purl.obolibrary.org/obo/UBERON_0008203) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cavitas pelvis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Pelvic_cavity" + + +### peptic cell `http://purl.obolibrary.org/obo/CL_0000155` + +#### Added +- [peptic cell](http://purl.obolibrary.org/obo/CL_0000155) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### pericardial cavity `http://purl.obolibrary.org/obo/UBERON_0001074` +#### Removed +- [pericardial cavity](http://purl.obolibrary.org/obo/UBERON_0001074) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cavitas pericardiaca" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Pericardial_cavity" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [pericardial cavity](http://purl.obolibrary.org/obo/UBERON_0001074) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cavitas pericardiaca" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Pericardial_cavity" + + +### pericardial fluid `http://purl.obolibrary.org/obo/UBERON_0002409` +#### Removed +- [pericardial fluid](http://purl.obolibrary.org/obo/UBERON_0002409) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D000069236" + +#### Added +- [pericardial fluid](http://purl.obolibrary.org/obo/UBERON_0002409) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D000069236" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [author_id](https://w3id.org/sssom/author_id) [0000-0001-9439-5346](https://orcid.org/0000-0001-9439-5346) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### pericranium `http://purl.obolibrary.org/obo/UBERON_0013687` +#### Removed +- [pericranium](http://purl.obolibrary.org/obo/UBERON_0013687) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "periosteum externum cranii" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:76623" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [pericranium](http://purl.obolibrary.org/obo/UBERON_0013687) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "periosteum externum cranii" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:76623" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### pericyte `http://purl.obolibrary.org/obo/CL_0000669` + +#### Added +- [pericyte](http://purl.obolibrary.org/obo/CL_0000669) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### periderm `http://purl.obolibrary.org/obo/UBERON_0003055` +#### Removed +- [periderm](http://purl.obolibrary.org/obo/UBERON_0003055) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0003377" + - [contributor](http://purl.org/dc/terms/contributor) "https://orcid.org/0000-0003-4423-4370" + +#### Added +- [periderm](http://purl.obolibrary.org/obo/UBERON_0003055) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0003377" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + - [author_id](https://w3id.org/sssom/author_id) [0000-0003-4423-4370](https://orcid.org/0000-0003-4423-4370) + + +### perilymph `http://purl.obolibrary.org/obo/UBERON_0001845` +#### Removed +- [perilymph](http://purl.obolibrary.org/obo/UBERON_0001845) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "liquor cotunnii" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Perilymph" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [perilymph](http://purl.obolibrary.org/obo/UBERON_0001845) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "liquor cotunnii" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Perilymph" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### periodontal ligament `http://purl.obolibrary.org/obo/UBERON_0008266` +#### Removed +- [periodontal ligament](http://purl.obolibrary.org/obo/UBERON_0008266) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D010513" + +- [periodontal ligament](http://purl.obolibrary.org/obo/UBERON_0008266) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "periodontal fiber" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Periodontal_ligament" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [periodontal ligament](http://purl.obolibrary.org/obo/UBERON_0008266) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "periodontal fibre" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Periodontal_ligament" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [periodontal ligament](http://purl.obolibrary.org/obo/UBERON_0008266) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "fibra periodontalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Periodontal_ligament" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [periodontal ligament](http://purl.obolibrary.org/obo/UBERON_0008266) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "fibra periodontalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Periodontal_ligament" + +- [periodontal ligament](http://purl.obolibrary.org/obo/UBERON_0008266) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "periodontal fibre" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Periodontal_ligament" + +- [periodontal ligament](http://purl.obolibrary.org/obo/UBERON_0008266) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "periodontal fiber" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Periodontal_ligament" + +- [periodontal ligament](http://purl.obolibrary.org/obo/UBERON_0008266) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D010513" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [author_id](https://w3id.org/sssom/author_id) [0000-0001-9439-5346](https://orcid.org/0000-0001-9439-5346) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### peripheral blood mononuclear cell `http://purl.obolibrary.org/obo/CL_2000001` + +#### Added +- [peripheral blood mononuclear cell](http://purl.obolibrary.org/obo/CL_2000001) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### peripheral nervous system `http://purl.obolibrary.org/obo/UBERON_0000010` +#### Removed +- [peripheral nervous system](http://purl.obolibrary.org/obo/UBERON_0000010) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pars peripherica" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Peripheral_nervous_system" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:9903" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [peripheral nervous system](http://purl.obolibrary.org/obo/UBERON_0000010) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005098" + +- [peripheral nervous system](http://purl.obolibrary.org/obo/UBERON_0000010) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "systema nervosum periphericum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Peripheral_nervous_system" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:9903" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [peripheral nervous system](http://purl.obolibrary.org/obo/UBERON_0000010) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pars peripherica" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Peripheral_nervous_system" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:9903" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [peripheral nervous system](http://purl.obolibrary.org/obo/UBERON_0000010) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "systema nervosum periphericum" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Peripheral_nervous_system" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:9903" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [peripheral nervous system](http://purl.obolibrary.org/obo/UBERON_0000010) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005098" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### peripheral nervous system neuron `http://purl.obolibrary.org/obo/CL_2000032` + +#### Added +- [peripheral nervous system neuron](http://purl.obolibrary.org/obo/CL_2000032) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### periportal region hepatocyte `http://purl.obolibrary.org/obo/CL_0019026` + +#### Added +- [periportal region hepatocyte](http://purl.obolibrary.org/obo/CL_0019026) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### perirenal fat `http://purl.obolibrary.org/obo/UBERON_0005406` +#### Removed +- [perirenal fat](http://purl.obolibrary.org/obo/UBERON_0005406) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "capsula adiposa renis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Adipose_capsule_of_kidney" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [perirenal fat](http://purl.obolibrary.org/obo/UBERON_0005406) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "capsula adiposa renis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Adipose_capsule_of_kidney" + + +### peritoneal cavity `http://purl.obolibrary.org/obo/UBERON_0001179` +#### Removed +- [peritoneal cavity](http://purl.obolibrary.org/obo/UBERON_0001179) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cavitas peritonealis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0001782" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Peritoneal_cavity" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [peritoneal cavity](http://purl.obolibrary.org/obo/UBERON_0001179) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "saccus serosus peritonei" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Peritoneal_cavity" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [peritoneal cavity](http://purl.obolibrary.org/obo/UBERON_0001179) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "saccus serosus peritonei" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Peritoneal_cavity" + +- [peritoneal cavity](http://purl.obolibrary.org/obo/UBERON_0001179) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cavitas peritonealis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0001782" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Peritoneal_cavity" + + +### peritoneal fluid `http://purl.obolibrary.org/obo/UBERON_0001268` + +#### Added +- [peritoneal fluid](http://purl.obolibrary.org/obo/UBERON_0001268) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D001202" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [LexicalMatching](https://w3id.org/semapv/vocab/LexicalMatching) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### peritubular capillary endothelial cell `http://purl.obolibrary.org/obo/CL_1001033` + +#### Added +- [peritubular capillary endothelial cell](http://purl.obolibrary.org/obo/CL_1001033) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### periventricular zone of hypothalamus `http://purl.obolibrary.org/obo/UBERON_0002271` +#### Removed +- [periventricular zone of hypothalamus](http://purl.obolibrary.org/obo/UBERON_0002271) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "zona periventricularis hypothalamicae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:77682" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [periventricular zone of hypothalamus](http://purl.obolibrary.org/obo/UBERON_0002271) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "zona periventricularis hypothalamicae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:77682" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### pes connective tissue `http://purl.obolibrary.org/obo/UBERON_0003595` +#### Removed +- [pes connective tissue](http://purl.obolibrary.org/obo/UBERON_0003595) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "textus connectivus of pes" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "OBOL:automatic" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [pes connective tissue](http://purl.obolibrary.org/obo/UBERON_0003595) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "textus connectivus of pes" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "OBOL:automatic" + + +### pes joint `http://purl.obolibrary.org/obo/UBERON_0001487` +#### Removed +- [pes joint](http://purl.obolibrary.org/obo/UBERON_0001487) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "articulationes pedis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:71349" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [pes joint](http://purl.obolibrary.org/obo/UBERON_0001487) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "articulationes pedis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:71349" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### phagocyte `http://purl.obolibrary.org/obo/CL_0000234` + +#### Added +- [phagocyte](http://purl.obolibrary.org/obo/CL_0000234) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### pharyngeal arch `http://purl.obolibrary.org/obo/UBERON_0002539` +#### Removed +- [pharyngeal arch](http://purl.obolibrary.org/obo/UBERON_0002539) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arcus pharyngei" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Pharyngeal_arch" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [pharyngeal arch](http://purl.obolibrary.org/obo/UBERON_0002539) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arcus pharyngei" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Pharyngeal_arch" + + +### pharyngeal arch 1 `http://purl.obolibrary.org/obo/UBERON_0004362` +#### Removed +- [pharyngeal arch 1](http://purl.obolibrary.org/obo/UBERON_0004362) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arcus pharyngeus primus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:First_pharyngeal_arch" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [pharyngeal arch 1](http://purl.obolibrary.org/obo/UBERON_0004362) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arcus pharyngeus primus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:First_pharyngeal_arch" + + +### pharyngeal arch 2 `http://purl.obolibrary.org/obo/UBERON_0003066` +#### Removed +- [pharyngeal arch 2](http://purl.obolibrary.org/obo/UBERON_0003066) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "arcus pharyngeus secundus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Second_pharyngeal_arch" + +#### Added +- [pharyngeal arch 2](http://purl.obolibrary.org/obo/UBERON_0003066) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "arcus pharyngeus secundus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Second_pharyngeal_arch" + + +### pharyngeal arch artery `http://purl.obolibrary.org/obo/UBERON_0004363` +#### Removed +- [pharyngeal arch artery](http://purl.obolibrary.org/obo/UBERON_0004363) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "a. arcuum pharyngeorum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Aortic_arches" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [pharyngeal arch artery](http://purl.obolibrary.org/obo/UBERON_0004363) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteriae arcuum pharyngeorum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Aortic_arches" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [pharyngeal arch artery](http://purl.obolibrary.org/obo/UBERON_0004363) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "a. arcuum pharyngeorum" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Aortic_arches" + +- [pharyngeal arch artery](http://purl.obolibrary.org/obo/UBERON_0004363) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteriae arcuum pharyngeorum" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Aortic_arches" + + +### pharyngeal arch cartilage `http://purl.obolibrary.org/obo/UBERON_0011004` +#### Removed +- [pharyngeal arch cartilage](http://purl.obolibrary.org/obo/UBERON_0011004) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0006051" + - [contributor](http://purl.org/dc/terms/contributor) "https://orcid.org/0000-0003-4423-4370" + +#### Added +- [pharyngeal arch cartilage](http://purl.obolibrary.org/obo/UBERON_0011004) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0006051" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + - [author_id](https://w3id.org/sssom/author_id) [0000-0003-4423-4370](https://orcid.org/0000-0003-4423-4370) + + +### pharyngeal cleft `http://purl.obolibrary.org/obo/UBERON_0005879` +#### Removed +- [pharyngeal cleft](http://purl.obolibrary.org/obo/UBERON_0005879) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "sulcus pharyngei" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Pharyngeal_groove" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [pharyngeal cleft](http://purl.obolibrary.org/obo/UBERON_0005879) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "sulcus pharyngei" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Pharyngeal_groove" + + +### pharyngeal mucosa `http://purl.obolibrary.org/obo/UBERON_0000355` +#### Removed +- [pharyngeal mucosa](http://purl.obolibrary.org/obo/UBERON_0000355) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica mucosa pharyngea" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:55031" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [pharyngeal mucosa](http://purl.obolibrary.org/obo/UBERON_0000355) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica mucosa pharyngea" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:55031" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### photoreceptor array `http://purl.obolibrary.org/obo/UBERON_0005388` +#### Removed +- [photoreceptor array](http://purl.obolibrary.org/obo/UBERON_0005388) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00004200" + +#### Added +- [photoreceptor array](http://purl.obolibrary.org/obo/UBERON_0005388) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00004200" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### photoreceptor cell `http://purl.obolibrary.org/obo/CL_0000210` + +#### Added +- [photoreceptor cell](http://purl.obolibrary.org/obo/CL_0000210) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### photoreceptor layer of retina `http://purl.obolibrary.org/obo/UBERON_0001787` +#### Removed +- [photoreceptor layer of retina](http://purl.obolibrary.org/obo/UBERON_0001787) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "stratum segmentorum externorum et internorum retinae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:58680" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [photoreceptor layer of retina](http://purl.obolibrary.org/obo/UBERON_0001787) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "stratum segmentorum externorum et internorum retinae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:58680" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### photosynthesis `http://purl.obolibrary.org/obo/GO_0015979` +#### Removed +- [photosynthesis](http://purl.obolibrary.org/obo/GO_0015979) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [prokaryote_subset](http://purl.obolibrary.org/obo/go#prokaryote_subset) + +#### Added +- [photosynthesis](http://purl.obolibrary.org/obo/GO_0015979) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_prokaryote](http://purl.obolibrary.org/obo/go#goslim_prokaryote) + + +### phrenic nerve `http://purl.obolibrary.org/obo/UBERON_0001884` +#### Removed +- [phrenic nerve](http://purl.obolibrary.org/obo/UBERON_0001884) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nervus phrenicus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0001063" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Phrenic_nerve" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [phrenic nerve](http://purl.obolibrary.org/obo/UBERON_0001884) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nervus phrenicus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0001063" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Phrenic_nerve" + + +### pigmented ciliary epithelial cell `http://purl.obolibrary.org/obo/CL_0002303` + +#### Added +- [pigmented ciliary epithelial cell](http://purl.obolibrary.org/obo/CL_0002303) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### pigmented epithelial cell `http://purl.obolibrary.org/obo/CL_0000529` + +#### Added +- [pigmented epithelial cell](http://purl.obolibrary.org/obo/CL_0000529) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### pigmented layer of retina `http://purl.obolibrary.org/obo/UBERON_0001782` +#### Removed +- [pigmented layer of retina](http://purl.obolibrary.org/obo/UBERON_0001782) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "stratum pigmentosum retinae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:58627" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [pigmented layer of retina](http://purl.obolibrary.org/obo/UBERON_0001782) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "p. pigmentosa retinae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Retinal_pigment_epithelium" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [pigmented layer of retina](http://purl.obolibrary.org/obo/UBERON_0001782) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "stratum pigmentosa retinae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Retinal_pigment_epithelium" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [pigmented layer of retina](http://purl.obolibrary.org/obo/UBERON_0001782) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "stratum pigmentosum retinae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:58627" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [pigmented layer of retina](http://purl.obolibrary.org/obo/UBERON_0001782) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "p. pigmentosa retinae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Retinal_pigment_epithelium" + +- [pigmented layer of retina](http://purl.obolibrary.org/obo/UBERON_0001782) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "stratum pigmentosa retinae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Retinal_pigment_epithelium" + + +### pineal body `http://purl.obolibrary.org/obo/UBERON_0001905` +#### Removed +- [pineal body](http://purl.obolibrary.org/obo/UBERON_0001905) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "glandula pinealis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:62033" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [pineal body](http://purl.obolibrary.org/obo/UBERON_0001905) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "glandula pinealis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:62033" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### piriform cortex `http://purl.obolibrary.org/obo/UBERON_0004725` +#### Removed +- [piriform cortex](http://purl.obolibrary.org/obo/UBERON_0004725) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cortex piriformis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Piriform_cortex" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [piriform cortex](http://purl.obolibrary.org/obo/UBERON_0004725) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "eupalaeocortex" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:165" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [piriform cortex](http://purl.obolibrary.org/obo/UBERON_0004725) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "regio praepiriformis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:165" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [piriform cortex](http://purl.obolibrary.org/obo/UBERON_0004725) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "area prepiriformis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:165" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [piriform cortex](http://purl.obolibrary.org/obo/UBERON_0004725) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "palaeocortex II" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:165" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [piriform cortex](http://purl.obolibrary.org/obo/UBERON_0004725) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "eupalaeocortex" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:165" + +- [piriform cortex](http://purl.obolibrary.org/obo/UBERON_0004725) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "regio praepiriformis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:165" + +- [piriform cortex](http://purl.obolibrary.org/obo/UBERON_0004725) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cortex piriformis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Piriform_cortex" + +- [piriform cortex](http://purl.obolibrary.org/obo/UBERON_0004725) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "area prepiriformis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:165" + +- [piriform cortex](http://purl.obolibrary.org/obo/UBERON_0004725) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "palaeocortex II" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:165" + + +### pituitary gland `http://purl.obolibrary.org/obo/UBERON_0000007` +#### Removed +- [pituitary gland](http://purl.obolibrary.org/obo/UBERON_0000007) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "glandula pituitaria" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Pituitary_gland" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [pituitary gland](http://purl.obolibrary.org/obo/UBERON_0000007) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "glandula pituitaria" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Pituitary_gland" + + +### pituitary gland cell `http://purl.obolibrary.org/obo/CL_2000004` + +#### Added +- [pituitary gland cell](http://purl.obolibrary.org/obo/CL_2000004) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### placental disc `http://purl.obolibrary.org/obo/UBERON_8600038` + +#### Added +- [placental disc](http://purl.obolibrary.org/obo/UBERON_8600038) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A disc-shaped structure that is part of the placenta. A placental disc supports fetal development through the exchange of nutrients between maternal and fetal bloodstreams. The placental disc is structured to keep the blood streams separate, while maximizing surface area for the transport of nutrients between them, to maintain an immunological barrier." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:35496035" + +- [placental disc](http://purl.obolibrary.org/obo/UBERON_8600038) [contributor](http://purl.org/dc/terms/contributor) [0000-0001-6677-8489](https://orcid.org/0000-0001-6677-8489) + +- [placental disc](http://purl.obolibrary.org/obo/UBERON_8600038) [label](http://www.w3.org/2000/01/rdf-schema#label) "placental disc" + +- [placental disc](http://purl.obolibrary.org/obo/UBERON_8600038) [date](http://purl.org/dc/terms/date) "2024-01-16T17:50:20Z"^^[dateTime](http://www.w3.org/2001/XMLSchema#dateTime) + +- [placental disc](http://purl.obolibrary.org/obo/UBERON_8600038) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "placental disk" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:30133439" + +- [placental disc](http://purl.obolibrary.org/obo/UBERON_8600038) [id](http://www.geneontology.org/formats/oboInOwl#id) "UBERON:8600038" + +- [placental disc](http://purl.obolibrary.org/obo/UBERON_8600038) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "uberon" + +- Class: [placental disc](http://purl.obolibrary.org/obo/UBERON_8600038) + +- [placental disc](http://purl.obolibrary.org/obo/UBERON_8600038) SubClassOf [anatomical structure](http://purl.obolibrary.org/obo/UBERON_0000061) + +- [placental disc](http://purl.obolibrary.org/obo/UBERON_8600038) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [placenta](http://purl.obolibrary.org/obo/UBERON_0001987) + + +### placental villous stroma `http://purl.obolibrary.org/obo/UBERON_8600023` + +#### Added +- [placental villous stroma](http://purl.obolibrary.org/obo/UBERON_8600023) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "uberon" + +- [placental villous stroma](http://purl.obolibrary.org/obo/UBERON_8600023) [date](http://purl.org/dc/terms/date) "2023-07-04T10:46:17Z"^^[dateTime](http://www.w3.org/2001/XMLSchema#dateTime) + +- [placental villous stroma](http://purl.obolibrary.org/obo/UBERON_8600023) [label](http://www.w3.org/2000/01/rdf-schema#label) "placental villous stroma" + +- [placental villous stroma](http://purl.obolibrary.org/obo/UBERON_8600023) [contributor](http://purl.org/dc/terms/contributor) [0000-0001-6677-8489](https://orcid.org/0000-0001-6677-8489) + +- [placental villous stroma](http://purl.obolibrary.org/obo/UBERON_8600023) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "chorionic villous stroma" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:12624135" + +- [placental villous stroma](http://purl.obolibrary.org/obo/UBERON_8600023) [contributor](http://purl.org/dc/terms/contributor) [0000-0001-7655-4833](https://orcid.org/0000-0001-7655-4833) + +- [placental villous stroma](http://purl.obolibrary.org/obo/UBERON_8600023) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "CVS" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:12624135" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [abbreviation](http://purl.obolibrary.org/obo/OMO_0003000) + +- [placental villous stroma](http://purl.obolibrary.org/obo/UBERON_8600023) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A stroma that is part of a chorionic villus (placental villus). A placental villous stroma supports the fetal capillaries and villous trophoblast." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:31512233" + +- [placental villous stroma](http://purl.obolibrary.org/obo/UBERON_8600023) [id](http://www.geneontology.org/formats/oboInOwl#id) "UBERON:8600023" + +- Class: [placental villous stroma](http://purl.obolibrary.org/obo/UBERON_8600023) + +- [placental villous stroma](http://purl.obolibrary.org/obo/UBERON_8600023) EquivalentTo [stroma](http://purl.obolibrary.org/obo/UBERON_0003891) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [chorionic villus](http://purl.obolibrary.org/obo/UBERON_0007106)) + +- [placental villous stroma](http://purl.obolibrary.org/obo/UBERON_8600023) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [chorionic villus](http://purl.obolibrary.org/obo/UBERON_0007106) + +- [placental villous stroma](http://purl.obolibrary.org/obo/UBERON_8600023) SubClassOf [stroma](http://purl.obolibrary.org/obo/UBERON_0003891) + + +### placental villous trophoblast `http://purl.obolibrary.org/obo/CL_2000060` + +#### Added +- [placental villous trophoblast](http://purl.obolibrary.org/obo/CL_2000060) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### plantar part of pes `http://purl.obolibrary.org/obo/UBERON_0008338` +#### Removed +- [plantar part of pes](http://purl.obolibrary.org/obo/UBERON_0008338) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regio plantaris" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [plantar part of pes](http://purl.obolibrary.org/obo/UBERON_0008338) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "planta" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Sole_(foot)" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [plantar part of pes](http://purl.obolibrary.org/obo/UBERON_0008338) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "planta" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [plantar part of pes](http://purl.obolibrary.org/obo/UBERON_0008338) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "planta" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [plantar part of pes](http://purl.obolibrary.org/obo/UBERON_0008338) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "planta" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Sole_(foot)" + +- [plantar part of pes](http://purl.obolibrary.org/obo/UBERON_0008338) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regio plantaris" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### plasma cell `http://purl.obolibrary.org/obo/CL_0000786` + +#### Added +- [plasma cell](http://purl.obolibrary.org/obo/CL_0000786) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### plasma membrane `http://purl.obolibrary.org/obo/GO_0005886` +#### Removed +- [plasma membrane](http://purl.obolibrary.org/obo/GO_0005886) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [prokaryote_subset](http://purl.obolibrary.org/obo/go#prokaryote_subset) + +#### Added +- [plasma membrane](http://purl.obolibrary.org/obo/GO_0005886) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_prokaryote](http://purl.obolibrary.org/obo/go#goslim_prokaryote) + + +### plasmablast `http://purl.obolibrary.org/obo/CL_0000980` + +#### Added +- [plasmablast](http://purl.obolibrary.org/obo/CL_0000980) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### plasmacytoid dendritic cell `http://purl.obolibrary.org/obo/CL_0000784` + +#### Added +- [plasmacytoid dendritic cell](http://purl.obolibrary.org/obo/CL_0000784) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### plasmacytoid dendritic cell, human `http://purl.obolibrary.org/obo/CL_0001058` + +#### Added +- [plasmacytoid dendritic cell, human](http://purl.obolibrary.org/obo/CL_0001058) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### plasmatocyte `http://purl.obolibrary.org/obo/CL_0000394` + +#### Added +- [plasmatocyte](http://purl.obolibrary.org/obo/CL_0000394) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### platelet `http://purl.obolibrary.org/obo/CL_0000233` + +#### Added +- [platelet](http://purl.obolibrary.org/obo/CL_0000233) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### pleural cavity `http://purl.obolibrary.org/obo/UBERON_0002402` +#### Removed +- [pleural cavity](http://purl.obolibrary.org/obo/UBERON_0002402) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cavitum pleurale" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Pleural_cavity" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [pleural cavity](http://purl.obolibrary.org/obo/UBERON_0002402) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cavitas pleuralis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Pleural_cavity" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [pleural cavity](http://purl.obolibrary.org/obo/UBERON_0002402) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cavitum pleuralae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Pleural_cavity" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [pleural cavity](http://purl.obolibrary.org/obo/UBERON_0002402) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cavitum pleuralae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Pleural_cavity" + +- [pleural cavity](http://purl.obolibrary.org/obo/UBERON_0002402) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cavitum pleurale" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Pleural_cavity" + +- [pleural cavity](http://purl.obolibrary.org/obo/UBERON_0002402) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cavitas pleuralis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Pleural_cavity" + + +### pneumocyte `http://purl.obolibrary.org/obo/CL_0000322` + +#### Added +- [pneumocyte](http://purl.obolibrary.org/obo/CL_0000322) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### podocyte `http://purl.obolibrary.org/obo/CL_0000653` + +#### Added +- [podocyte](http://purl.obolibrary.org/obo/CL_0000653) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### pons `http://purl.obolibrary.org/obo/UBERON_0000988` +#### Removed +- [pons](http://purl.obolibrary.org/obo/UBERON_0000988) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "pons cerebri" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:547" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [pons](http://purl.obolibrary.org/obo/UBERON_0000988) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "pons cerebri" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:547" + + +### pontine raphe nucleus `http://purl.obolibrary.org/obo/UBERON_0002047` +#### Removed +- [pontine raphe nucleus](http://purl.obolibrary.org/obo/UBERON_0002047) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus raphe pontis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:589" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [pontine raphe nucleus](http://purl.obolibrary.org/obo/UBERON_0002047) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus raphes pontis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Pontine_raphe_nucleus" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [pontine raphe nucleus](http://purl.obolibrary.org/obo/UBERON_0002047) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "raphe (mediana pontina)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:589" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [pontine raphe nucleus](http://purl.obolibrary.org/obo/UBERON_0002047) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "raphe pontis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:68875" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [pontine raphe nucleus](http://purl.obolibrary.org/obo/UBERON_0002047) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus raphe pontis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:589" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [pontine raphe nucleus](http://purl.obolibrary.org/obo/UBERON_0002047) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "raphe pontis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:68875" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [pontine raphe nucleus](http://purl.obolibrary.org/obo/UBERON_0002047) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "raphe (mediana pontina)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:589" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [pontine raphe nucleus](http://purl.obolibrary.org/obo/UBERON_0002047) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus raphes pontis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Pontine_raphe_nucleus" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### pontine tegmentum `http://purl.obolibrary.org/obo/UBERON_0003023` +#### Removed +- [pontine tegmentum](http://purl.obolibrary.org/obo/UBERON_0003023) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "pars posterior pontis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:557" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [pontine tegmentum](http://purl.obolibrary.org/obo/UBERON_0003023) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tegmentum pontis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Pontine_tegmentum" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [pontine tegmentum](http://purl.obolibrary.org/obo/UBERON_0003023) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tegmentum pontis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:71108" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [pontine tegmentum](http://purl.obolibrary.org/obo/UBERON_0003023) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "pars dorsalis pontis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:557" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [pontine tegmentum](http://purl.obolibrary.org/obo/UBERON_0003023) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D065821" + +#### Added +- [pontine tegmentum](http://purl.obolibrary.org/obo/UBERON_0003023) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tegmentum pontis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Pontine_tegmentum" + +- [pontine tegmentum](http://purl.obolibrary.org/obo/UBERON_0003023) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "pars dorsalis pontis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:557" + +- [pontine tegmentum](http://purl.obolibrary.org/obo/UBERON_0003023) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tegmentum pontis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:71108" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [pontine tegmentum](http://purl.obolibrary.org/obo/UBERON_0003023) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "pars posterior pontis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:557" + +- [pontine tegmentum](http://purl.obolibrary.org/obo/UBERON_0003023) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D065821" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [author_id](https://w3id.org/sssom/author_id) [0000-0001-9439-5346](https://orcid.org/0000-0001-9439-5346) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### popliteal vein `http://purl.obolibrary.org/obo/UBERON_0001544` +#### Removed +- [popliteal vein](http://purl.obolibrary.org/obo/UBERON_0001544) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vena poplitea" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Popliteal_vein" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [popliteal vein](http://purl.obolibrary.org/obo/UBERON_0001544) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vena poplitea" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Popliteal_vein" + + +### portal triad `http://purl.obolibrary.org/obo/UBERON_0001279` +#### Removed +- [portal triad](http://purl.obolibrary.org/obo/UBERON_0001279) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "trias hepatica" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Portal_triad" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [portal triad](http://purl.obolibrary.org/obo/UBERON_0001279) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "trias hepatica" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Portal_triad" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### positive regulation of amino acid biosynthetic process `http://purl.obolibrary.org/obo/GO_2000284` +#### Removed +- [positive regulation of amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_2000284) [created by](http://www.geneontology.org/formats/oboInOwl#created_by) "vw" + +- [positive regulation of amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_2000284) [label](http://www.w3.org/2000/01/rdf-schema#label) "positive regulation of amino acid biosynthetic process" + +- [positive regulation of amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_2000284) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that activates or increases the frequency, rate or extent of cellular amino acid biosynthetic process." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:obol" + +- [positive regulation of amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_2000284) [creation date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2010-12-10T11:54:27Z" + +- [positive regulation of amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_2000284) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:2000284" + +- [positive regulation of amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_2000284) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of amino acid anabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:obol" + +- [positive regulation of amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_2000284) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of cellular amino acid biosynthetic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:obol" + +- [positive regulation of amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_2000284) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of amino acid formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:obol" + +- [positive regulation of amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_2000284) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of amino acid biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:obol" + +- [positive regulation of amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_2000284) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of amino acid synthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:obol" + +- [positive regulation of amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_2000284) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- Class: [positive regulation of amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_2000284) + +- [positive regulation of amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_2000284) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0008652)) + +- [positive regulation of amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_2000284) SubClassOf [positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0008652) + +- [positive regulation of amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_2000284) SubClassOf [regulation of cellular amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_2000282) + +- [positive regulation of amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_2000284) SubClassOf [positive regulation of amino acid metabolic process](http://purl.obolibrary.org/obo/GO_0045764) + +- [positive regulation of amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_2000284) SubClassOf [positive regulation of biosynthetic process](http://purl.obolibrary.org/obo/GO_0009891) + + + +### positive regulation of amino acid metabolic process `http://purl.obolibrary.org/obo/GO_0045764` +#### Removed +- [positive regulation of amino acid metabolic process](http://purl.obolibrary.org/obo/GO_0045764) SubClassOf [positive regulation of nitrogen compound metabolic process](http://purl.obolibrary.org/obo/GO_0051173) + +- [positive regulation of amino acid metabolic process](http://purl.obolibrary.org/obo/GO_0045764) SubClassOf [positive regulation of cellular metabolic process](http://purl.obolibrary.org/obo/GO_0031325) + +- [positive regulation of amino acid metabolic process](http://purl.obolibrary.org/obo/GO_0045764) SubClassOf [positive regulation of small molecule metabolic process](http://purl.obolibrary.org/obo/GO_0062013) + + + +### positive regulation of calcium ion import `http://purl.obolibrary.org/obo/GO_0090280` + +#### Added +- [positive regulation of calcium ion import](http://purl.obolibrary.org/obo/GO_0090280) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that increases the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:BHF" + +- [positive regulation of calcium ion import](http://purl.obolibrary.org/obo/GO_0090280) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0090280" + +- [positive regulation of calcium ion import](http://purl.obolibrary.org/obo/GO_0090280) [label](http://www.w3.org/2000/01/rdf-schema#label) "positive regulation of calcium ion import" + +- [positive regulation of calcium ion import](http://purl.obolibrary.org/obo/GO_0090280) [creation date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2010-02-08T05:11:20Z" + +- [positive regulation of calcium ion import](http://purl.obolibrary.org/obo/GO_0090280) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "positive regulation of transmembrane calcium influx" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:tb" + +- [positive regulation of calcium ion import](http://purl.obolibrary.org/obo/GO_0090280) [created by](http://www.geneontology.org/formats/oboInOwl#created_by) "tb" + +- [positive regulation of calcium ion import](http://purl.obolibrary.org/obo/GO_0090280) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- Class: [positive regulation of calcium ion import](http://purl.obolibrary.org/obo/GO_0090280) + +- [positive regulation of calcium ion import](http://purl.obolibrary.org/obo/GO_0090280) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [calcium ion import](http://purl.obolibrary.org/obo/GO_0070509)) + +- [positive regulation of calcium ion import](http://purl.obolibrary.org/obo/GO_0090280) SubClassOf [positive regulation of calcium ion transport](http://purl.obolibrary.org/obo/GO_0051928) + +- [positive regulation of calcium ion import](http://purl.obolibrary.org/obo/GO_0090280) SubClassOf [regulation of calcium ion import](http://purl.obolibrary.org/obo/GO_0090279) + +- [positive regulation of calcium ion import](http://purl.obolibrary.org/obo/GO_0090280) SubClassOf [positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [calcium ion import](http://purl.obolibrary.org/obo/GO_0070509) + + +### positive regulation of calcium ion import across plasma membrane `http://purl.obolibrary.org/obo/GO_1905665` + +#### Added +- [positive regulation of calcium ion import across plasma membrane](http://purl.obolibrary.org/obo/GO_1905665) SubClassOf [positive regulation of calcium ion import](http://purl.obolibrary.org/obo/GO_0090280) + + +### positive regulation of cytoplasmic transport `http://purl.obolibrary.org/obo/GO_1903651` +#### Removed +- [positive regulation of cytoplasmic transport](http://purl.obolibrary.org/obo/GO_1903651) [has narrow synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "up regulation of cytoplasmic streaming" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of cytoplasmic transport](http://purl.obolibrary.org/obo/GO_1903651) [has narrow synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "activation of cytoplasmic transport" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of cytoplasmic transport](http://purl.obolibrary.org/obo/GO_1903651) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that activates or increases the frequency, rate or extent of cytoplasmic transport." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:25049409" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GO_REF:0000058" + +- [positive regulation of cytoplasmic transport](http://purl.obolibrary.org/obo/GO_1903651) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of cytoplasmic transport" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of cytoplasmic transport](http://purl.obolibrary.org/obo/GO_1903651) [created by](http://www.geneontology.org/formats/oboInOwl#created_by) "jl" + +- [positive regulation of cytoplasmic transport](http://purl.obolibrary.org/obo/GO_1903651) [has narrow synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "activation of cytoplasmic streaming" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of cytoplasmic transport](http://purl.obolibrary.org/obo/GO_1903651) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of cytoplasmic transport" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of cytoplasmic transport](http://purl.obolibrary.org/obo/GO_1903651) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [positive regulation of cytoplasmic transport](http://purl.obolibrary.org/obo/GO_1903651) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of cytoplasmic transport" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of cytoplasmic transport](http://purl.obolibrary.org/obo/GO_1903651) [creation date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2014-11-24T13:38:34Z" + +- [positive regulation of cytoplasmic transport](http://purl.obolibrary.org/obo/GO_1903651) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1903651" + +- [positive regulation of cytoplasmic transport](http://purl.obolibrary.org/obo/GO_1903651) [label](http://www.w3.org/2000/01/rdf-schema#label) "positive regulation of cytoplasmic transport" + +- [positive regulation of cytoplasmic transport](http://purl.obolibrary.org/obo/GO_1903651) [has narrow synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "upregulation of cytoplasmic streaming" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of cytoplasmic transport](http://purl.obolibrary.org/obo/GO_1903651) [has narrow synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "positive regulation of cytoplasmic streaming" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of cytoplasmic transport](http://purl.obolibrary.org/obo/GO_1903651) [has narrow synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "up-regulation of cytoplasmic streaming" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- Class: [positive regulation of cytoplasmic transport](http://purl.obolibrary.org/obo/GO_1903651) + +- [positive regulation of cytoplasmic transport](http://purl.obolibrary.org/obo/GO_1903651) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [cytosolic transport](http://purl.obolibrary.org/obo/GO_0016482)) + +- [positive regulation of cytoplasmic transport](http://purl.obolibrary.org/obo/GO_1903651) SubClassOf [regulation of cytoplasmic transport](http://purl.obolibrary.org/obo/GO_1903649) + +- [positive regulation of cytoplasmic transport](http://purl.obolibrary.org/obo/GO_1903651) SubClassOf [positive regulation of intracellular transport](http://purl.obolibrary.org/obo/GO_0032388) + +- [positive regulation of cytoplasmic transport](http://purl.obolibrary.org/obo/GO_1903651) SubClassOf [positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [cytosolic transport](http://purl.obolibrary.org/obo/GO_0016482) + + + +### positive regulation of dense core granule transport `http://purl.obolibrary.org/obo/GO_1904811` +#### Removed +- [positive regulation of dense core granule transport](http://purl.obolibrary.org/obo/GO_1904811) SubClassOf [positive regulation of cytoplasmic transport](http://purl.obolibrary.org/obo/GO_1903651) + +#### Added +- [positive regulation of dense core granule transport](http://purl.obolibrary.org/obo/GO_1904811) SubClassOf [positive regulation of intracellular transport](http://purl.obolibrary.org/obo/GO_0032388) + + +### positive regulation of gamma-aminobutyric acid catabolic process `http://purl.obolibrary.org/obo/GO_1901717` + +#### Added +- [positive regulation of gamma-aminobutyric acid catabolic process](http://purl.obolibrary.org/obo/GO_1901717) SubClassOf [positive regulation of cellular metabolic process](http://purl.obolibrary.org/obo/GO_0031325) + +- [positive regulation of gamma-aminobutyric acid catabolic process](http://purl.obolibrary.org/obo/GO_1901717) SubClassOf [positive regulation of small molecule metabolic process](http://purl.obolibrary.org/obo/GO_0062013) + + +### positive regulation of glutamate metabolic process `http://purl.obolibrary.org/obo/GO_2000213` + +#### Added +- [positive regulation of glutamate metabolic process](http://purl.obolibrary.org/obo/GO_2000213) SubClassOf [positive regulation of small molecule metabolic process](http://purl.obolibrary.org/obo/GO_0062013) + +- [positive regulation of glutamate metabolic process](http://purl.obolibrary.org/obo/GO_2000213) SubClassOf [positive regulation of cellular metabolic process](http://purl.obolibrary.org/obo/GO_0031325) + + +### positive regulation of nitric oxide biosynthetic process `http://purl.obolibrary.org/obo/GO_0045429` +#### Removed +- [positive regulation of nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0045429) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of nitric oxide biosynthetic process" + +- [positive regulation of nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0045429) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:go_curators" + +- [positive regulation of nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0045429) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0045429" + +- [positive regulation of nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0045429) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of nitric oxide biosynthesis" + +- [positive regulation of nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0045429) [label](http://www.w3.org/2000/01/rdf-schema#label) "positive regulation of nitric oxide biosynthetic process" + +- [positive regulation of nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0045429) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [positive regulation of nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0045429) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of nitric oxide formation" + +- [positive regulation of nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0045429) [has narrow synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "stimulation of nitric oxide biosynthetic process" + +- [positive regulation of nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0045429) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of nitric oxide anabolism" + +- [positive regulation of nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0045429) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of nitric oxide synthesis" + +- [positive regulation of nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0045429) [has narrow synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "activation of nitric oxide biosynthetic process" + +- [positive regulation of nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0045429) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of nitric oxide biosynthetic process" + +- [positive regulation of nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0045429) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of nitric oxide biosynthetic process" + +- Class: [positive regulation of nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0045429) + +- [positive regulation of nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0045429) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0006809)) + +- [positive regulation of nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0045429) SubClassOf [positive regulation of nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_1904407) + +- [positive regulation of nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0045429) SubClassOf [positive regulation of nitrogen compound metabolic process](http://purl.obolibrary.org/obo/GO_0051173) + +- [positive regulation of nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0045429) SubClassOf [positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0006809) + +- [positive regulation of nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0045429) SubClassOf [regulation of nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0045428) + +- [positive regulation of nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0045429) SubClassOf [positive regulation of cellular biosynthetic process](http://purl.obolibrary.org/obo/GO_0031328) + + + +### positive regulation of nitric oxide metabolic process `http://purl.obolibrary.org/obo/GO_1904407` +#### Removed +- [positive regulation of nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_1904407) [created by](http://www.geneontology.org/formats/oboInOwl#created_by) "sl" + +- [positive regulation of nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_1904407) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of nitric oxide metabolic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_1904407) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [positive regulation of nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_1904407) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of nitric oxide metabolic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_1904407) [creation date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2015-06-24T20:56:47Z" + +- [positive regulation of nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_1904407) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of nitric oxide metabolic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_1904407) [has narrow synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "activation of nitric oxide metabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_1904407) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1904407" + +- [positive regulation of nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_1904407) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that activates or increases the frequency, rate or extent of nitric oxide metabolic process." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:11991626" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GO_REF:0000058" + +- [positive regulation of nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_1904407) [has narrow synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "activation of nitric oxide metabolic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_1904407) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "upregulation of nitric oxide metabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_1904407) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up-regulation of nitric oxide metabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_1904407) [label](http://www.w3.org/2000/01/rdf-schema#label) "positive regulation of nitric oxide metabolic process" + +- [positive regulation of nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_1904407) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "up regulation of nitric oxide metabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [positive regulation of nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_1904407) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "positive regulation of nitric oxide metabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- Class: [positive regulation of nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_1904407) + +- [positive regulation of nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_1904407) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_0046209)) + +- [positive regulation of nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_1904407) SubClassOf [regulation of nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_0080164) + +- [positive regulation of nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_1904407) SubClassOf [positively regulates](http://purl.obolibrary.org/obo/RO_0002213) some [nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_0046209) + +- [positive regulation of nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_1904407) SubClassOf [positive regulation of metabolic process](http://purl.obolibrary.org/obo/GO_0009893) + + + +### postcranial axial skeleton `http://purl.obolibrary.org/obo/UBERON_0002090` + +#### Added +- [postcranial axial skeleton](http://purl.obolibrary.org/obo/UBERON_0002090) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D013131" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [LexicalMatching](https://w3id.org/semapv/vocab/LexicalMatching) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### posterior communicating artery `http://purl.obolibrary.org/obo/UBERON_0001628` +#### Removed +- [posterior communicating artery](http://purl.obolibrary.org/obo/UBERON_0001628) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria cerebri communicans posterior" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Posterior_communicating_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [posterior communicating artery](http://purl.obolibrary.org/obo/UBERON_0001628) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria cerebri communicans posterior" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Posterior_communicating_artery" + + +### posterior hypothalamic region `http://purl.obolibrary.org/obo/UBERON_0002770` +#### Removed +- [posterior hypothalamic region](http://purl.obolibrary.org/obo/UBERON_0002770) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "regio hypothalamica posterior" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:411" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [posterior hypothalamic region](http://purl.obolibrary.org/obo/UBERON_0002770) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "hypothalamus posterior" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:411" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [posterior hypothalamic region](http://purl.obolibrary.org/obo/UBERON_0002770) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "regio hypothalamica posterior" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:411" + +- [posterior hypothalamic region](http://purl.obolibrary.org/obo/UBERON_0002770) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "hypothalamus posterior" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:411" + + +### posterior segment of eyeball `http://purl.obolibrary.org/obo/UBERON_0001802` +#### Removed +- [posterior segment of eyeball](http://purl.obolibrary.org/obo/UBERON_0001802) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "segmentum posterius bulbi oculi" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Posterior_segment_of_eyeball" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [posterior segment of eyeball](http://purl.obolibrary.org/obo/UBERON_0001802) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "segmentum posterius bulbi oculi" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Posterior_segment_of_eyeball" + + +### posterior surface of kidney `http://purl.obolibrary.org/obo/UBERON_0035471` +#### Removed +- [posterior surface of kidney](http://purl.obolibrary.org/obo/UBERON_0035471) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "facies posterior renis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:15590" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [posterior surface of kidney](http://purl.obolibrary.org/obo/UBERON_0035471) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "facies posterior renis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:15590" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### posterior surface of prostate `http://purl.obolibrary.org/obo/UBERON_0035165` +#### Removed +- [posterior surface of prostate](http://purl.obolibrary.org/obo/UBERON_0035165) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "facies posterior prostatae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:19592" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [posterior surface of prostate](http://purl.obolibrary.org/obo/UBERON_0035165) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "facies posterior prostatae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:19592" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### posterior vena cava `http://purl.obolibrary.org/obo/UBERON_0001072` +#### Removed +- [posterior vena cava](http://purl.obolibrary.org/obo/UBERON_0001072) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vena cava inferior" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Inferior_vena_cava" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0002682" + +#### Added +- [posterior vena cava](http://purl.obolibrary.org/obo/UBERON_0001072) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vena cava inferior" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Inferior_vena_cava" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0002682" + + +### posteroventral cochlear nucleus `http://purl.obolibrary.org/obo/UBERON_0002831` +#### Removed +- [posteroventral cochlear nucleus](http://purl.obolibrary.org/obo/UBERON_0002831) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus cochlearis posteroventralis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:724" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [posteroventral cochlear nucleus](http://purl.obolibrary.org/obo/UBERON_0002831) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus cochlearis posteroventralis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:724" + + +### pre-B-I cell `http://purl.obolibrary.org/obo/CL_0000956` + +#### Added +- [pre-B-I cell](http://purl.obolibrary.org/obo/CL_0000956) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### pre-conventional dendritic cell `http://purl.obolibrary.org/obo/CL_0002010` + +#### Added +- [pre-conventional dendritic cell](http://purl.obolibrary.org/obo/CL_0002010) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### pre-natural killer cell `http://purl.obolibrary.org/obo/CL_0000937` + +#### Added +- [pre-natural killer cell](http://purl.obolibrary.org/obo/CL_0000937) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### precursor B cell `http://purl.obolibrary.org/obo/CL_0000817` + +#### Added +- [precursor B cell](http://purl.obolibrary.org/obo/CL_0000817) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### precursor cell `http://purl.obolibrary.org/obo/CL_0011115` + +#### Added +- [precursor cell](http://purl.obolibrary.org/obo/CL_0011115) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### premacula segment of distal straight tubule `http://purl.obolibrary.org/obo/UBERON_0006376` +#### Removed +- [premacula segment of distal straight tubule](http://purl.obolibrary.org/obo/UBERON_0006376) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "https://sourceforge.net/tracker/?func=detail&aid=3123600&group_id=76834&atid=1205376" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:14595018" + +#### Added +- [premacula segment of distal straight tubule](http://purl.obolibrary.org/obo/UBERON_0006376) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Missing definition for term UBERON:0006376. Please replace it using linked reference." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:14595018" + +- [premacula segment of distal straight tubule](http://purl.obolibrary.org/obo/UBERON_0006376) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) "https://sourceforge.net/tracker/?func=detail&aid=3123600&group_id=76834&atid=1205376"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + + +### preoptic area `http://purl.obolibrary.org/obo/UBERON_0001928` +#### Removed +- [preoptic area](http://purl.obolibrary.org/obo/UBERON_0001928) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "area preoptica" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Preoptic_area" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [preoptic area](http://purl.obolibrary.org/obo/UBERON_0001928) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nuclei preoptici" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:377" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [preoptic area](http://purl.obolibrary.org/obo/UBERON_0001928) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "area preoptica" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Preoptic_area" + +- [preoptic area](http://purl.obolibrary.org/obo/UBERON_0001928) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nuclei preoptici" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:377" + + +### preoptic nucleus `http://purl.obolibrary.org/obo/UBERON_0007251` + +#### Added +- [preoptic nucleus](http://purl.obolibrary.org/obo/UBERON_0007251) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D011301" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [LexicalMatching](https://w3id.org/semapv/vocab/LexicalMatching) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### preoptic periventricular nucleus `http://purl.obolibrary.org/obo/UBERON_0002622` +#### Removed +- [preoptic periventricular nucleus](http://purl.obolibrary.org/obo/UBERON_0002622) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus periventricularis preopticus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:379" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [preoptic periventricular nucleus](http://purl.obolibrary.org/obo/UBERON_0002622) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus periventricularis praeopticus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:379" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [preoptic periventricular nucleus](http://purl.obolibrary.org/obo/UBERON_0002622) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus periventricularis hypothalami, pars dorsalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:379" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [preoptic periventricular nucleus](http://purl.obolibrary.org/obo/UBERON_0002622) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nucleus preopticus periventricularis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:62324" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [preoptic periventricular nucleus](http://purl.obolibrary.org/obo/UBERON_0002622) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus periventricularis hypothalami, pars dorsalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:379" + +- [preoptic periventricular nucleus](http://purl.obolibrary.org/obo/UBERON_0002622) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus periventricularis praeopticus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:379" + +- [preoptic periventricular nucleus](http://purl.obolibrary.org/obo/UBERON_0002622) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus periventricularis preopticus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:379" + +- [preoptic periventricular nucleus](http://purl.obolibrary.org/obo/UBERON_0002622) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nucleus preopticus periventricularis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:62324" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### preosteoblast `http://purl.obolibrary.org/obo/CL_0007010` + +#### Added +- [preosteoblast](http://purl.obolibrary.org/obo/CL_0007010) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### prepuce of penis `http://purl.obolibrary.org/obo/UBERON_0001332` +#### Removed +- [prepuce of penis](http://purl.obolibrary.org/obo/UBERON_0001332) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "prepucium" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Foreskin" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [prepuce of penis](http://purl.obolibrary.org/obo/UBERON_0001332) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "praeputium" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Foreskin" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [prepuce of penis](http://purl.obolibrary.org/obo/UBERON_0001332) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "preputium penis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:19639" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [prepuce of penis](http://purl.obolibrary.org/obo/UBERON_0001332) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "praeputium" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Foreskin" + +- [prepuce of penis](http://purl.obolibrary.org/obo/UBERON_0001332) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "preputium penis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:19639" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [prepuce of penis](http://purl.obolibrary.org/obo/UBERON_0001332) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "prepucium" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Foreskin" + + +### prickle cell `http://purl.obolibrary.org/obo/CL_0000649` + +#### Added +- [prickle cell](http://purl.obolibrary.org/obo/CL_0000649) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### primary cultured cell `http://purl.obolibrary.org/obo/CL_0000001` + +#### Added +- [primary cultured cell](http://purl.obolibrary.org/obo/CL_0000001) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### primary metabolic process `http://purl.obolibrary.org/obo/GO_0044238` + +#### Added +- [primary metabolic process](http://purl.obolibrary.org/obo/GO_0044238) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [gocheck_do_not_annotate](http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate) + +- [primary metabolic process](http://purl.obolibrary.org/obo/GO_0044238) [term tracker item](http://purl.obolibrary.org/obo/IAO_0000233) "https://github.com/geneontology/go-ontology/issues/26424"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + + +### primary motor cortex `http://purl.obolibrary.org/obo/UBERON_0001384` +#### Removed +- [primary motor cortex](http://purl.obolibrary.org/obo/UBERON_0001384) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "gyrus precentralis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Primary_motor_cortex" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [primary motor cortex](http://purl.obolibrary.org/obo/UBERON_0001384) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "gyrus precentralis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Primary_motor_cortex" + + +### primary ovarian follicle `http://purl.obolibrary.org/obo/UBERON_0000035` +#### Removed +- [primary ovarian follicle](http://purl.obolibrary.org/obo/UBERON_0000035) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "folliculus ovaricus primarius" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:18634" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [primary ovarian follicle](http://purl.obolibrary.org/obo/UBERON_0000035) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "folliculus ovaricus primarius" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:18634" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### primary sensory neuron (sensu Teleostei) `http://purl.obolibrary.org/obo/CL_0000531` + +#### Added +- [primary sensory neuron (sensu Teleostei)](http://purl.obolibrary.org/obo/CL_0000531) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### primitive heart tube `http://purl.obolibrary.org/obo/UBERON_0005498` +#### Removed +- [primitive heart tube](http://purl.obolibrary.org/obo/UBERON_0005498) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0006179" + - [contributor](http://purl.org/dc/terms/contributor) "https://orcid.org/0000-0003-4423-4370" + +#### Added +- [primitive heart tube](http://purl.obolibrary.org/obo/UBERON_0005498) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0006179" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + - [author_id](https://w3id.org/sssom/author_id) [0000-0003-4423-4370](https://orcid.org/0000-0003-4423-4370) + + +### primitive red blood cell `http://purl.obolibrary.org/obo/CL_0002355` + +#### Added +- [primitive red blood cell](http://purl.obolibrary.org/obo/CL_0002355) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### primitive streak `http://purl.obolibrary.org/obo/UBERON_0004341` +#### Removed +- [primitive streak](http://purl.obolibrary.org/obo/UBERON_0004341) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D054240" + +#### Added +- [primitive streak](http://purl.obolibrary.org/obo/UBERON_0004341) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D054240" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [author_id](https://w3id.org/sssom/author_id) [0000-0001-9439-5346](https://orcid.org/0000-0001-9439-5346) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### primitive urogenital sinus `http://purl.obolibrary.org/obo/UBERON_0000164` +#### Removed +- [primitive urogenital sinus](http://purl.obolibrary.org/obo/UBERON_0000164) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sinus urogenitalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [primitive urogenital sinus](http://purl.obolibrary.org/obo/UBERON_0000164) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sinus urogenitalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### primordial germ cell `http://purl.obolibrary.org/obo/CL_0000670` + +#### Added +- [primordial germ cell](http://purl.obolibrary.org/obo/CL_0000670) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### primordium `http://purl.obolibrary.org/obo/UBERON_0001048` +#### Removed +- [primordium](http://purl.obolibrary.org/obo/UBERON_0001048) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005495" + +#### Added +- [primordium](http://purl.obolibrary.org/obo/UBERON_0001048) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005495" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### pro-B cell `http://purl.obolibrary.org/obo/CL_0000826` + +#### Added +- [pro-B cell](http://purl.obolibrary.org/obo/CL_0000826) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### pro-T cell `http://purl.obolibrary.org/obo/CL_0000827` + +#### Added +- [pro-T cell](http://purl.obolibrary.org/obo/CL_0000827) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### proctodeum `http://purl.obolibrary.org/obo/UBERON_0000931` +#### Removed +- [proctodeum](http://purl.obolibrary.org/obo/UBERON_0000931) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00000123" + +#### Added +- [proctodeum](http://purl.obolibrary.org/obo/UBERON_0000931) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00000123" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### proerythroblast `http://purl.obolibrary.org/obo/CL_0000547` +#### Removed +- [proerythroblast](http://purl.obolibrary.org/obo/CL_0000547) EquivalentTo [erythroid lineage cell](http://purl.obolibrary.org/obo/CL_0000764) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [basophilic cytoplasm](http://purl.obolibrary.org/obo/CL_0017503)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [obsolete increased nucleus size](http://purl.obolibrary.org/obo/CL_0017505)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [nucleolus](http://purl.obolibrary.org/obo/GO_0005730)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD2 molecule](http://purl.obolibrary.org/obo/PR_000001083)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6G](http://purl.obolibrary.org/obo/PR_000002978)) and ([bearer of](http://purl.obolibrary.org/obo/RO_0000053) some [nucleated](http://purl.obolibrary.org/obo/PATO_0002505)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [transferrin receptor protein 1](http://purl.obolibrary.org/obo/PR_000001945)) + +- [proerythroblast](http://purl.obolibrary.org/obo/CL_0000547) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [obsolete increased nucleus size](http://purl.obolibrary.org/obo/CL_0017505) + +#### Added +- [proerythroblast](http://purl.obolibrary.org/obo/CL_0000547) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + +- [proerythroblast](http://purl.obolibrary.org/obo/CL_0000547) EquivalentTo [erythroid lineage cell](http://purl.obolibrary.org/obo/CL_0000764) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [basophilic cytoplasm](http://purl.obolibrary.org/obo/CL_0017503)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [nucleolus](http://purl.obolibrary.org/obo/GO_0005730)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD19 molecule](http://purl.obolibrary.org/obo/PR_000001002)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD4 molecule](http://purl.obolibrary.org/obo/PR_000001004)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD3 epsilon](http://purl.obolibrary.org/obo/PR_000001020)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [neural cell adhesion molecule 1](http://purl.obolibrary.org/obo/PR_000001024)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD2 molecule](http://purl.obolibrary.org/obo/PR_000001083)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD8 alpha chain](http://purl.obolibrary.org/obo/PR_000001084)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [membrane-spanning 4-domains subfamily A member 1](http://purl.obolibrary.org/obo/PR_000001289)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [T-cell surface glycoprotein CD5](http://purl.obolibrary.org/obo/PR_000001839)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [CD14 molecule](http://purl.obolibrary.org/obo/PR_000001889)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [lymphocyte antigen 6G](http://purl.obolibrary.org/obo/PR_000002978)) and ([bearer of](http://purl.obolibrary.org/obo/RO_0000053) some [nucleated](http://purl.obolibrary.org/obo/PATO_0002505)) and ([bearer of](http://purl.obolibrary.org/obo/RO_0000053) some [high nuclear/cytoplasmic ratio](http://purl.obolibrary.org/obo/PATO_0040072)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [transferrin receptor protein 1](http://purl.obolibrary.org/obo/PR_000001945)) + +- [proerythroblast](http://purl.obolibrary.org/obo/CL_0000547) SubClassOf [bearer of](http://purl.obolibrary.org/obo/RO_0000053) some [high nuclear/cytoplasmic ratio](http://purl.obolibrary.org/obo/PATO_0040072) + + +### professional antigen presenting cell `http://purl.obolibrary.org/obo/CL_0000145` + +#### Added +- [professional antigen presenting cell](http://purl.obolibrary.org/obo/CL_0000145) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### progenitor cell `http://purl.obolibrary.org/obo/CL_0011026` + +#### Added +- [progenitor cell](http://purl.obolibrary.org/obo/CL_0011026) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### progenitor cell of endocrine pancreas `http://purl.obolibrary.org/obo/CL_0002351` + +#### Added +- [progenitor cell of endocrine pancreas](http://purl.obolibrary.org/obo/CL_0002351) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### progenitor cell of mammary luminal epithelium `http://purl.obolibrary.org/obo/CL_0009116` + +#### Added +- [progenitor cell of mammary luminal epithelium](http://purl.obolibrary.org/obo/CL_0009116) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### programmed cell death `http://purl.obolibrary.org/obo/GO_0012501` +#### Removed +- [programmed cell death](http://purl.obolibrary.org/obo/GO_0012501) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [prokaryote_subset](http://purl.obolibrary.org/obo/go#prokaryote_subset) + +#### Added +- [programmed cell death](http://purl.obolibrary.org/obo/GO_0012501) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_prokaryote](http://purl.obolibrary.org/obo/go#goslim_prokaryote) + + +### prokaryote_subset `http://purl.obolibrary.org/obo/go#prokaryote_subset` +#### Removed +- AnnotationProperty: [prokaryote_subset](http://purl.obolibrary.org/obo/go#prokaryote_subset) + +- [prokaryote_subset](http://purl.obolibrary.org/obo/go#prokaryote_subset) SubPropertyOf: [subset_property](http://www.geneontology.org/formats/oboInOwl#SubsetProperty) + + + +### promonocyte `http://purl.obolibrary.org/obo/CL_0000559` + +#### Added +- [promonocyte](http://purl.obolibrary.org/obo/CL_0000559) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### promyelocyte `http://purl.obolibrary.org/obo/CL_0000836` +#### Removed +- [promyelocyte](http://purl.obolibrary.org/obo/CL_0000836) EquivalentTo [myeloid lineage restricted progenitor cell](http://purl.obolibrary.org/obo/CL_0000839) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [basophilic cytoplasm](http://purl.obolibrary.org/obo/CL_0017503)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [obsolete increased nucleus size](http://purl.obolibrary.org/obo/CL_0017505)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [nucleolus](http://purl.obolibrary.org/obo/GO_0005730)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [azurophil granule](http://purl.obolibrary.org/obo/GO_0042582)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [low affinity immunoglobulin gamma Fc region receptor III](http://purl.obolibrary.org/obo/PR_000001483)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [signal transducer CD24](http://purl.obolibrary.org/obo/PR_000001932)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [alpha-(1,3)-fucosyltransferase 4](http://purl.obolibrary.org/obo/PR_000001456)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD33 molecule](http://purl.obolibrary.org/obo/PR_000001892)) + +- [promyelocyte](http://purl.obolibrary.org/obo/CL_0000836) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [obsolete increased nucleus size](http://purl.obolibrary.org/obo/CL_0017505) + +#### Added +- [promyelocyte](http://purl.obolibrary.org/obo/CL_0000836) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + +- [promyelocyte](http://purl.obolibrary.org/obo/CL_0000836) EquivalentTo [myeloid lineage restricted progenitor cell](http://purl.obolibrary.org/obo/CL_0000839) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [basophilic cytoplasm](http://purl.obolibrary.org/obo/CL_0017503)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [nucleolus](http://purl.obolibrary.org/obo/GO_0005730)) and ([has part](http://purl.obolibrary.org/obo/BFO_0000051) some [azurophil granule](http://purl.obolibrary.org/obo/GO_0042582)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [integrin alpha-M](http://purl.obolibrary.org/obo/PR_000001012)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [low affinity immunoglobulin gamma Fc region receptor III](http://purl.obolibrary.org/obo/PR_000001483)) and ([lacks_plasma_membrane_part](http://purl.obolibrary.org/obo/CL_4030046) some [signal transducer CD24](http://purl.obolibrary.org/obo/PR_000001932)) and ([bearer of](http://purl.obolibrary.org/obo/RO_0000053) some [high nuclear/cytoplasmic ratio](http://purl.obolibrary.org/obo/PATO_0040072)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [alpha-(1,3)-fucosyltransferase 4](http://purl.obolibrary.org/obo/PR_000001456)) and ([has plasma membrane part](http://purl.obolibrary.org/obo/RO_0002104) some [CD33 molecule](http://purl.obolibrary.org/obo/PR_000001892)) + +- [promyelocyte](http://purl.obolibrary.org/obo/CL_0000836) SubClassOf [bearer of](http://purl.obolibrary.org/obo/RO_0000053) some [high nuclear/cytoplasmic ratio](http://purl.obolibrary.org/obo/PATO_0040072) + + +### pronephric duct `http://purl.obolibrary.org/obo/UBERON_0003060` +#### Removed +- [pronephric duct](http://purl.obolibrary.org/obo/UBERON_0003060) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ductus pronephricus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Pronephric_duct" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [pronephric duct](http://purl.obolibrary.org/obo/UBERON_0003060) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0005991" + - [contributor](http://purl.org/dc/terms/contributor) "https://orcid.org/0000-0003-4423-4370" + +#### Added +- [pronephric duct](http://purl.obolibrary.org/obo/UBERON_0003060) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ductus pronephricus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Pronephric_duct" + +- [pronephric duct](http://purl.obolibrary.org/obo/UBERON_0003060) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0005991" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + - [author_id](https://w3id.org/sssom/author_id) [0000-0003-4423-4370](https://orcid.org/0000-0003-4423-4370) + + +### pronephros `http://purl.obolibrary.org/obo/UBERON_0002120` +#### Removed +- [pronephros](http://purl.obolibrary.org/obo/UBERON_0002120) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D060910" + +#### Added +- [pronephros](http://purl.obolibrary.org/obo/UBERON_0002120) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D060910" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [author_id](https://w3id.org/sssom/author_id) [0000-0001-9439-5346](https://orcid.org/0000-0001-9439-5346) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### prostate gland `http://purl.obolibrary.org/obo/UBERON_0002367` +#### Removed +- [prostate gland](http://purl.obolibrary.org/obo/UBERON_0002367) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "prostata" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Prostate" + +#### Added +- [prostate gland](http://purl.obolibrary.org/obo/UBERON_0002367) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "prostata" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Prostate" + + +### prostate gland microvascular endothelial cell `http://purl.obolibrary.org/obo/CL_2000059` + +#### Added +- [prostate gland microvascular endothelial cell](http://purl.obolibrary.org/obo/CL_2000059) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### prostate gland smooth muscle `http://purl.obolibrary.org/obo/UBERON_0004243` +#### Removed +- [prostate gland smooth muscle](http://purl.obolibrary.org/obo/UBERON_0004243) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "substantia muscularis prostatae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:74245" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [prostate gland smooth muscle](http://purl.obolibrary.org/obo/UBERON_0004243) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "substantia muscularis prostatae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:74245" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### prostate stromal cell `http://purl.obolibrary.org/obo/CL_0002622` + +#### Added +- [prostate stromal cell](http://purl.obolibrary.org/obo/CL_0002622) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### prostatic urethra `http://purl.obolibrary.org/obo/UBERON_0001335` +#### Removed +- [prostatic urethra](http://purl.obolibrary.org/obo/UBERON_0001335) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pars prostatica urethrae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MP:0011777" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Prostatic_urethra" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [prostatic urethra](http://purl.obolibrary.org/obo/UBERON_0001335) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pars prostatica urethrae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MP:0011777" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Prostatic_urethra" + + +### prostatic venous plexus `http://purl.obolibrary.org/obo/UBERON_0009042` +#### Removed +- [prostatic venous plexus](http://purl.obolibrary.org/obo/UBERON_0009042) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "plexus venosus prostaticus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Prostatic_venous_plexus" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [prostatic venous plexus](http://purl.obolibrary.org/obo/UBERON_0009042) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "plexus venosus prostaticus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Prostatic_venous_plexus" + + +### protein catabolic process `http://purl.obolibrary.org/obo/GO_0030163` +#### Removed +- [protein catabolic process](http://purl.obolibrary.org/obo/GO_0030163) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [prokaryote_subset](http://purl.obolibrary.org/obo/go#prokaryote_subset) + +#### Added +- [protein catabolic process](http://purl.obolibrary.org/obo/GO_0030163) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_prokaryote](http://purl.obolibrary.org/obo/go#goslim_prokaryote) + + +### protein localization to membrane `http://purl.obolibrary.org/obo/GO_0072657` +#### Removed +- [protein localization to membrane](http://purl.obolibrary.org/obo/GO_0072657) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [prokaryote_subset](http://purl.obolibrary.org/obo/go#prokaryote_subset) + +#### Added +- [protein localization to membrane](http://purl.obolibrary.org/obo/GO_0072657) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_prokaryote](http://purl.obolibrary.org/obo/go#goslim_prokaryote) + + +### protein maturation `http://purl.obolibrary.org/obo/GO_0051604` +#### Removed +- [protein maturation](http://purl.obolibrary.org/obo/GO_0051604) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [prokaryote_subset](http://purl.obolibrary.org/obo/go#prokaryote_subset) + +#### Added +- [protein maturation](http://purl.obolibrary.org/obo/GO_0051604) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_prokaryote](http://purl.obolibrary.org/obo/go#goslim_prokaryote) + + +### protein modification process `http://purl.obolibrary.org/obo/GO_0036211` +#### Removed +- [protein modification process](http://purl.obolibrary.org/obo/GO_0036211) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [prokaryote_subset](http://purl.obolibrary.org/obo/go#prokaryote_subset) + +#### Added +- [protein modification process](http://purl.obolibrary.org/obo/GO_0036211) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_prokaryote](http://purl.obolibrary.org/obo/go#goslim_prokaryote) + + +### protein-containing complex assembly `http://purl.obolibrary.org/obo/GO_0065003` +#### Removed +- [protein-containing complex assembly](http://purl.obolibrary.org/obo/GO_0065003) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [prokaryote_subset](http://purl.obolibrary.org/obo/go#prokaryote_subset) + +#### Added +- [protein-containing complex assembly](http://purl.obolibrary.org/obo/GO_0065003) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_prokaryote](http://purl.obolibrary.org/obo/go#goslim_prokaryote) + + +### proximal convoluted tubule `http://purl.obolibrary.org/obo/UBERON_0001287` +#### Removed +- [proximal convoluted tubule](http://purl.obolibrary.org/obo/UBERON_0001287) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tubulus contortus proximalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Proximal_convoluted_tubule" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [proximal convoluted tubule](http://purl.obolibrary.org/obo/UBERON_0001287) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tubulus convolutus proximalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [proximal convoluted tubule](http://purl.obolibrary.org/obo/UBERON_0001287) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tubulus convolutus proximalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [proximal convoluted tubule](http://purl.obolibrary.org/obo/UBERON_0001287) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tubulus contortus proximalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Proximal_convoluted_tubule" + + +### proximal epiphysis of fibula `http://purl.obolibrary.org/obo/UBERON_0008775` +#### Removed +- [proximal epiphysis of fibula](http://purl.obolibrary.org/obo/UBERON_0008775) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "caput fibulae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Head_of_fibula" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [proximal epiphysis of fibula](http://purl.obolibrary.org/obo/UBERON_0008775) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "caput fibulae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Head_of_fibula" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### proximal epiphysis of metacarpal bone `http://purl.obolibrary.org/obo/UBERON_0004416` +#### Removed +- [proximal epiphysis of metacarpal bone](http://purl.obolibrary.org/obo/UBERON_0004416) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "basis ossis metacarpi" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:33795" + +#### Added +- [proximal epiphysis of metacarpal bone](http://purl.obolibrary.org/obo/UBERON_0004416) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "basis ossis metacarpi" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:33795" + + +### proximal epiphysis of metatarsal bone `http://purl.obolibrary.org/obo/UBERON_0004415` +#### Removed +- [proximal epiphysis of metatarsal bone](http://purl.obolibrary.org/obo/UBERON_0004415) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "basis ossis metatarsi" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:33817" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [proximal epiphysis of metatarsal bone](http://purl.obolibrary.org/obo/UBERON_0004415) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "basis ossis metatarsi" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:33817" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### proximal epiphysis of phalanx of manus `http://purl.obolibrary.org/obo/UBERON_0004414` +#### Removed +- [proximal epiphysis of phalanx of manus](http://purl.obolibrary.org/obo/UBERON_0004414) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "basis phalangis manus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:226482" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [proximal epiphysis of phalanx of manus](http://purl.obolibrary.org/obo/UBERON_0004414) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "basis phalangis manus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:226482" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### proximal phalanx of manus `http://purl.obolibrary.org/obo/UBERON_0002234` +#### Removed +- [proximal phalanx of manus](http://purl.obolibrary.org/obo/UBERON_0002234) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "phalanx proximalis manus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:75816" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [proximal phalanx of manus](http://purl.obolibrary.org/obo/UBERON_0002234) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "phalanx proximalis manus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:75816" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### proximal phalanx of pes `http://purl.obolibrary.org/obo/UBERON_0003868` +#### Removed +- [proximal phalanx of pes](http://purl.obolibrary.org/obo/UBERON_0003868) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "phalanx proximalis pedis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:75828" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [proximal phalanx of pes](http://purl.obolibrary.org/obo/UBERON_0003868) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "phalanx proximalis pedis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:75828" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### pudendal vein `http://purl.obolibrary.org/obo/UBERON_0009029` +#### Removed +- [pudendal vein](http://purl.obolibrary.org/obo/UBERON_0009029) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "vena pudendales" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "doi:10.1002/ca.23705" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [pudendal vein](http://purl.obolibrary.org/obo/UBERON_0009029) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "vena pudendae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "doi:10.1002/ca.23705" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [pudendal vein](http://purl.obolibrary.org/obo/UBERON_0009029) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "vena pudendales" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "doi:10.1002/ca.23705" + +- [pudendal vein](http://purl.obolibrary.org/obo/UBERON_0009029) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "vena pudendae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "doi:10.1002/ca.23705" + + +### pulmonary acinus `http://purl.obolibrary.org/obo/UBERON_0008874` +#### Removed +- [pulmonary acinus](http://purl.obolibrary.org/obo/UBERON_0008874) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "acinus pulmonaris" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:7313" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [pulmonary acinus](http://purl.obolibrary.org/obo/UBERON_0008874) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "arbor alveolaris" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:7313" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [pulmonary acinus](http://purl.obolibrary.org/obo/UBERON_0008874) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "arbor alveolaris" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:7313" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [pulmonary acinus](http://purl.obolibrary.org/obo/UBERON_0008874) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "acinus pulmonaris" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:7313" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### pulmonary alveolar duct `http://purl.obolibrary.org/obo/UBERON_0002173` +#### Removed +- [pulmonary alveolar duct](http://purl.obolibrary.org/obo/UBERON_0002173) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ductus alveolaris" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:7341" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [pulmonary alveolar duct](http://purl.obolibrary.org/obo/UBERON_0002173) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ductus alveolaris" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:7341" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### pulmonary artery `http://purl.obolibrary.org/obo/UBERON_0002012` +#### Removed +- [pulmonary artery](http://purl.obolibrary.org/obo/UBERON_0002012) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria pulmonalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Pulmonary_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [pulmonary artery](http://purl.obolibrary.org/obo/UBERON_0002012) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "truncus pulmonalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Pulmonary_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [pulmonary artery](http://purl.obolibrary.org/obo/UBERON_0002012) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria pulmonalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Pulmonary_artery" + +- [pulmonary artery](http://purl.obolibrary.org/obo/UBERON_0002012) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "truncus pulmonalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Pulmonary_artery" + + +### pulmonary artery endothelial cell `http://purl.obolibrary.org/obo/CL_1001568` + +#### Added +- [pulmonary artery endothelial cell](http://purl.obolibrary.org/obo/CL_1001568) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### pulmonary interstitial fibroblast `http://purl.obolibrary.org/obo/CL_0002241` + +#### Added +- [pulmonary interstitial fibroblast](http://purl.obolibrary.org/obo/CL_0002241) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### pulmonary ionocyte `http://purl.obolibrary.org/obo/CL_0017000` + +#### Added +- [pulmonary ionocyte](http://purl.obolibrary.org/obo/CL_0017000) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### pulmonary lobule `http://purl.obolibrary.org/obo/UBERON_0010368` +#### Removed +- [pulmonary lobule](http://purl.obolibrary.org/obo/UBERON_0010368) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lobulus pulmonis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:75739" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [pulmonary lobule](http://purl.obolibrary.org/obo/UBERON_0010368) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lobulus pulmonis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:75739" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### pulmonary surfactant `http://purl.obolibrary.org/obo/UBERON_0008826` +#### Removed +- [pulmonary surfactant](http://purl.obolibrary.org/obo/UBERON_0008826) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D011663" + +#### Added +- [pulmonary surfactant](http://purl.obolibrary.org/obo/UBERON_0008826) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D011663" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [author_id](https://w3id.org/sssom/author_id) [0000-0001-9439-5346](https://orcid.org/0000-0001-9439-5346) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### pulmonary vein `http://purl.obolibrary.org/obo/UBERON_0002016` +#### Removed +- [pulmonary vein](http://purl.obolibrary.org/obo/UBERON_0002016) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "venae pulmonales" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Pulmonary_vein" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [pulmonary vein](http://purl.obolibrary.org/obo/UBERON_0002016) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "venae pulmonales" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Pulmonary_vein" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### pvalb GABAergic cortical interneuron `http://purl.obolibrary.org/obo/CL_4023018` + +#### Added +- [pvalb GABAergic cortical interneuron](http://purl.obolibrary.org/obo/CL_4023018) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### pyloric antrum `http://purl.obolibrary.org/obo/UBERON_0001165` +#### Removed +- [pyloric antrum](http://purl.obolibrary.org/obo/UBERON_0001165) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "antrum pyloricum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Pyloric_antrum" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0001732" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [pyloric antrum](http://purl.obolibrary.org/obo/UBERON_0001165) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "antrum pyloricum" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Pyloric_antrum" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0001732" + + +### pyloric canal `http://purl.obolibrary.org/obo/UBERON_0008858` +#### Removed +- [pyloric canal](http://purl.obolibrary.org/obo/UBERON_0008858) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "canalis pyloricus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Pyloric_canal" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [pyloric canal](http://purl.obolibrary.org/obo/UBERON_0008858) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "canalis pyloricus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Pyloric_canal" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### pylorus `http://purl.obolibrary.org/obo/UBERON_0001166` +#### Removed +- [pylorus](http://purl.obolibrary.org/obo/UBERON_0001166) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "valvula pylori" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Pylorus" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [pylorus](http://purl.obolibrary.org/obo/UBERON_0001166) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pars pylorica" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [pylorus](http://purl.obolibrary.org/obo/UBERON_0001166) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pars pylorica gastricae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:14581" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [pylorus](http://purl.obolibrary.org/obo/UBERON_0001166) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "valvula pylori" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Pylorus" + +- [pylorus](http://purl.obolibrary.org/obo/UBERON_0001166) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pars pylorica" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [pylorus](http://purl.obolibrary.org/obo/UBERON_0001166) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pars pylorica gastricae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:14581" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### pyramidal neuron `http://purl.obolibrary.org/obo/CL_0000598` + +#### Added +- [pyramidal neuron](http://purl.obolibrary.org/obo/CL_0000598) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### radial glial cell `http://purl.obolibrary.org/obo/CL_0000681` + +#### Added +- [radial glial cell](http://purl.obolibrary.org/obo/CL_0000681) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### raphe nuclei `http://purl.obolibrary.org/obo/UBERON_0004684` +#### Removed +- [raphe nuclei](http://purl.obolibrary.org/obo/UBERON_0004684) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nuclei raphes" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Raphe_nuclei" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [raphe nuclei](http://purl.obolibrary.org/obo/UBERON_0004684) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nuclei raphes" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:84017" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [raphe nuclei](http://purl.obolibrary.org/obo/UBERON_0004684) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nuclei raphes" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:84017" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [raphe nuclei](http://purl.obolibrary.org/obo/UBERON_0004684) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nuclei raphes" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Raphe_nuclei" + + +### rectal venous plexus `http://purl.obolibrary.org/obo/UBERON_0008887` +#### Removed +- [rectal venous plexus](http://purl.obolibrary.org/obo/UBERON_0008887) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "plexus venosus rectalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Rectal_venous_plexus" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [rectal venous plexus](http://purl.obolibrary.org/obo/UBERON_0008887) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "plexus haemorrhoidalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Rectal_venous_plexus" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [rectal venous plexus](http://purl.obolibrary.org/obo/UBERON_0008887) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "plexus venosus rectalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Rectal_venous_plexus" + +- [rectal venous plexus](http://purl.obolibrary.org/obo/UBERON_0008887) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "plexus haemorrhoidalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Rectal_venous_plexus" + + +### recurrent laryngeal nerve `http://purl.obolibrary.org/obo/UBERON_0003716` +#### Removed +- [recurrent laryngeal nerve](http://purl.obolibrary.org/obo/UBERON_0003716) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nervus laryngeus recurrens" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Recurrent_laryngeal_nerve" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [recurrent laryngeal nerve](http://purl.obolibrary.org/obo/UBERON_0003716) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nervus laryngeus recurrens" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Recurrent_laryngeal_nerve" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### red bone marrow `http://purl.obolibrary.org/obo/UBERON_0000361` +#### Removed +- [red bone marrow](http://purl.obolibrary.org/obo/UBERON_0000361) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "medulla ossium rubra" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0001160" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [red bone marrow](http://purl.obolibrary.org/obo/UBERON_0000361) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "medulla ossium rubra" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0001160" + + +### red pulp of spleen `http://purl.obolibrary.org/obo/UBERON_0001250` +#### Removed +- [red pulp of spleen](http://purl.obolibrary.org/obo/UBERON_0001250) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pulpa rubra" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:15844" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [red pulp of spleen](http://purl.obolibrary.org/obo/UBERON_0001250) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "pulpa splenica" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Red_pulp" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [red pulp of spleen](http://purl.obolibrary.org/obo/UBERON_0001250) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "pulpa splenica" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Red_pulp" + +- [red pulp of spleen](http://purl.obolibrary.org/obo/UBERON_0001250) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pulpa rubra" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:15844" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### regular atrial cardiac myocyte `http://purl.obolibrary.org/obo/CL_0002129` + +#### Added +- [regular atrial cardiac myocyte](http://purl.obolibrary.org/obo/CL_0002129) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### regular ventricular cardiac myocyte `http://purl.obolibrary.org/obo/CL_0002131` + +#### Added +- [regular ventricular cardiac myocyte](http://purl.obolibrary.org/obo/CL_0002131) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### regulation of calcium ion import `http://purl.obolibrary.org/obo/GO_0090279` + +#### Added +- [regulation of calcium ion import](http://purl.obolibrary.org/obo/GO_0090279) [label](http://www.w3.org/2000/01/rdf-schema#label) "regulation of calcium ion import" + +- [regulation of calcium ion import](http://purl.obolibrary.org/obo/GO_0090279) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [regulation of calcium ion import](http://purl.obolibrary.org/obo/GO_0090279) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0090279" + +- [regulation of calcium ion import](http://purl.obolibrary.org/obo/GO_0090279) [creation date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2010-02-08T05:11:20Z" + +- [regulation of calcium ion import](http://purl.obolibrary.org/obo/GO_0090279) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that modulates the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:BHF" + +- [regulation of calcium ion import](http://purl.obolibrary.org/obo/GO_0090279) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "regulation of transmembrane calcium influx" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:tb" + +- [regulation of calcium ion import](http://purl.obolibrary.org/obo/GO_0090279) [created by](http://www.geneontology.org/formats/oboInOwl#created_by) "tb" + +- Class: [regulation of calcium ion import](http://purl.obolibrary.org/obo/GO_0090279) + +- [regulation of calcium ion import](http://purl.obolibrary.org/obo/GO_0090279) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([regulates](http://purl.obolibrary.org/obo/RO_0002211) some [calcium ion import](http://purl.obolibrary.org/obo/GO_0070509)) + +- [regulation of calcium ion import](http://purl.obolibrary.org/obo/GO_0090279) SubClassOf [regulation of calcium ion transport](http://purl.obolibrary.org/obo/GO_0051924) + +- [regulation of calcium ion import](http://purl.obolibrary.org/obo/GO_0090279) SubClassOf [regulates](http://purl.obolibrary.org/obo/RO_0002211) some [calcium ion import](http://purl.obolibrary.org/obo/GO_0070509) + + +### regulation of calcium ion import across plasma membrane `http://purl.obolibrary.org/obo/GO_1905664` + +#### Added +- [regulation of calcium ion import across plasma membrane](http://purl.obolibrary.org/obo/GO_1905664) SubClassOf [regulation of calcium ion import](http://purl.obolibrary.org/obo/GO_0090279) + + +### regulation of cellular amino acid biosynthetic process `http://purl.obolibrary.org/obo/GO_2000282` +#### Removed +- [regulation of cellular amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_2000282) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [regulation of cellular amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_2000282) [label](http://www.w3.org/2000/01/rdf-schema#label) "regulation of cellular amino acid biosynthetic process" + +- [regulation of cellular amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_2000282) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:2000282" + +- [regulation of cellular amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_2000282) [creation date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2010-12-10T11:54:19Z" + +- [regulation of cellular amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_2000282) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of cellular amino acid anabolism" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:obol" + +- [regulation of cellular amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_2000282) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of cellular amino acid biosynthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:obol" + +- [regulation of cellular amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_2000282) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of cellular amino acid synthesis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:obol" + +- [regulation of cellular amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_2000282) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of cellular amino acid formation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:obol" + +- [regulation of cellular amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_2000282) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of amino acid biosynthetic process" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:obol" + +- [regulation of cellular amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_2000282) [created by](http://www.geneontology.org/formats/oboInOwl#created_by) "vw" + +- [regulation of cellular amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_2000282) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that modulates the frequency, rate or extent of cellular amino acid biosynthetic process." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:obol" + +- Class: [regulation of cellular amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_2000282) + +- [regulation of cellular amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_2000282) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([regulates](http://purl.obolibrary.org/obo/RO_0002211) some [amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0008652)) + +- [regulation of cellular amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_2000282) SubClassOf [regulation of cellular amino acid metabolic process](http://purl.obolibrary.org/obo/GO_0006521) + +- [regulation of cellular amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_2000282) SubClassOf [regulation of biosynthetic process](http://purl.obolibrary.org/obo/GO_0009889) + +- [regulation of cellular amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_2000282) SubClassOf [regulates](http://purl.obolibrary.org/obo/RO_0002211) some [amino acid biosynthetic process](http://purl.obolibrary.org/obo/GO_0008652) + + + +### regulation of cellular amino acid metabolic process `http://purl.obolibrary.org/obo/GO_0006521` +#### Removed +- [regulation of cellular amino acid metabolic process](http://purl.obolibrary.org/obo/GO_0006521) SubClassOf [regulation of nitrogen compound metabolic process](http://purl.obolibrary.org/obo/GO_0051171) + + + +### regulation of cytoplasmic transport `http://purl.obolibrary.org/obo/GO_1903649` +#### Removed +- [regulation of cytoplasmic transport](http://purl.obolibrary.org/obo/GO_1903649) [created by](http://www.geneontology.org/formats/oboInOwl#created_by) "jl" + +- [regulation of cytoplasmic transport](http://purl.obolibrary.org/obo/GO_1903649) [label](http://www.w3.org/2000/01/rdf-schema#label) "regulation of cytoplasmic transport" + +- [regulation of cytoplasmic transport](http://purl.obolibrary.org/obo/GO_1903649) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that modulates the frequency, rate or extent of cytoplasmic transport." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:25049409" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GO_REF:0000058" + +- [regulation of cytoplasmic transport](http://purl.obolibrary.org/obo/GO_1903649) [has narrow synonym](http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym) "regulation of cytoplasmic streaming" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:TermGenie" + +- [regulation of cytoplasmic transport](http://purl.obolibrary.org/obo/GO_1903649) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:1903649" + +- [regulation of cytoplasmic transport](http://purl.obolibrary.org/obo/GO_1903649) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [regulation of cytoplasmic transport](http://purl.obolibrary.org/obo/GO_1903649) [creation date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2014-11-24T13:38:17Z" + +- Class: [regulation of cytoplasmic transport](http://purl.obolibrary.org/obo/GO_1903649) + +- [regulation of cytoplasmic transport](http://purl.obolibrary.org/obo/GO_1903649) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([regulates](http://purl.obolibrary.org/obo/RO_0002211) some [cytosolic transport](http://purl.obolibrary.org/obo/GO_0016482)) + +- [regulation of cytoplasmic transport](http://purl.obolibrary.org/obo/GO_1903649) SubClassOf [regulates](http://purl.obolibrary.org/obo/RO_0002211) some [cytosolic transport](http://purl.obolibrary.org/obo/GO_0016482) + +- [regulation of cytoplasmic transport](http://purl.obolibrary.org/obo/GO_1903649) SubClassOf [regulation of intracellular transport](http://purl.obolibrary.org/obo/GO_0032386) + + + +### regulation of dense core granule transport `http://purl.obolibrary.org/obo/GO_1904809` +#### Removed +- [regulation of dense core granule transport](http://purl.obolibrary.org/obo/GO_1904809) SubClassOf [regulation of cytoplasmic transport](http://purl.obolibrary.org/obo/GO_1903649) + +#### Added +- [regulation of dense core granule transport](http://purl.obolibrary.org/obo/GO_1904809) SubClassOf [regulation of intracellular transport](http://purl.obolibrary.org/obo/GO_0032386) + + +### regulation of nitric oxide biosynthetic process `http://purl.obolibrary.org/obo/GO_0045428` +#### Removed +- [regulation of nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0045428) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of nitric oxide biosynthesis" + +- [regulation of nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0045428) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of nitric oxide synthesis" + +- [regulation of nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0045428) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:go_curators" + +- [regulation of nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0045428) [label](http://www.w3.org/2000/01/rdf-schema#label) "regulation of nitric oxide biosynthetic process" + +- [regulation of nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0045428) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of nitric oxide anabolism" + +- [regulation of nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0045428) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regulation of nitric oxide formation" + +- [regulation of nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0045428) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [regulation of nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0045428) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0045428" + +- Class: [regulation of nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0045428) + +- [regulation of nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0045428) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([regulates](http://purl.obolibrary.org/obo/RO_0002211) some [nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0006809)) + +- [regulation of nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0045428) SubClassOf [regulation of nitrogen compound metabolic process](http://purl.obolibrary.org/obo/GO_0051171) + +- [regulation of nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0045428) SubClassOf [regulates](http://purl.obolibrary.org/obo/RO_0002211) some [nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0006809) + +- [regulation of nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0045428) SubClassOf [regulation of cellular biosynthetic process](http://purl.obolibrary.org/obo/GO_0031326) + +- [regulation of nitric oxide biosynthetic process](http://purl.obolibrary.org/obo/GO_0045428) SubClassOf [regulation of nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_0080164) + + + +### regulation of nitric oxide metabolic process `http://purl.obolibrary.org/obo/GO_0080164` +#### Removed +- [regulation of nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_0080164) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [regulation of nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_0080164) [created by](http://www.geneontology.org/formats/oboInOwl#created_by) "dhl" + +- [regulation of nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_0080164) [label](http://www.w3.org/2000/01/rdf-schema#label) "regulation of nitric oxide metabolic process" + +- [regulation of nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_0080164) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0080164" + +- [regulation of nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_0080164) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:DHL" + +- [regulation of nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_0080164) [creation date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2010-09-23T04:02:50Z" + +- Class: [regulation of nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_0080164) + +- [regulation of nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_0080164) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([regulates](http://purl.obolibrary.org/obo/RO_0002211) some [nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_0046209)) + +- [regulation of nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_0080164) SubClassOf [regulates](http://purl.obolibrary.org/obo/RO_0002211) some [nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_0046209) + +- [regulation of nitric oxide metabolic process](http://purl.obolibrary.org/obo/GO_0080164) SubClassOf [regulation of metabolic process](http://purl.obolibrary.org/obo/GO_0019222) + + + +### regulation of synaptic signaling by nitric oxide `http://purl.obolibrary.org/obo/GO_0150045` +#### Removed +- [regulation of synaptic signaling by nitric oxide](http://purl.obolibrary.org/obo/GO_0150045) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0150045" + +- [regulation of synaptic signaling by nitric oxide](http://purl.obolibrary.org/obo/GO_0150045) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that modulates the frequency, rate or extent of synaptic signaling by nitric oxide." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:26311509" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:bc" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:aruk" + +- [regulation of synaptic signaling by nitric oxide](http://purl.obolibrary.org/obo/GO_0150045) [label](http://www.w3.org/2000/01/rdf-schema#label) "regulation of synaptic signaling by nitric oxide" + +- [regulation of synaptic signaling by nitric oxide](http://purl.obolibrary.org/obo/GO_0150045) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_synapse](http://purl.obolibrary.org/obo/go#goslim_synapse) + +- [regulation of synaptic signaling by nitric oxide](http://purl.obolibrary.org/obo/GO_0150045) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [regulation of synaptic signaling by nitric oxide](http://purl.obolibrary.org/obo/GO_0150045) [created by](http://www.geneontology.org/formats/oboInOwl#created_by) "bc" + +- [regulation of synaptic signaling by nitric oxide](http://purl.obolibrary.org/obo/GO_0150045) [creation date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2018-04-23T09:42:25Z" + +- Class: [regulation of synaptic signaling by nitric oxide](http://purl.obolibrary.org/obo/GO_0150045) + +- [regulation of synaptic signaling by nitric oxide](http://purl.obolibrary.org/obo/GO_0150045) EquivalentTo [biological regulation](http://purl.obolibrary.org/obo/GO_0065007) and ([regulates](http://purl.obolibrary.org/obo/RO_0002211) some [synaptic signaling by nitric oxide](http://purl.obolibrary.org/obo/GO_0099163)) + +- [regulation of synaptic signaling by nitric oxide](http://purl.obolibrary.org/obo/GO_0150045) SubClassOf [regulation of cell communication](http://purl.obolibrary.org/obo/GO_0010646) + +- [regulation of synaptic signaling by nitric oxide](http://purl.obolibrary.org/obo/GO_0150045) SubClassOf [regulates](http://purl.obolibrary.org/obo/RO_0002211) some [synaptic signaling by nitric oxide](http://purl.obolibrary.org/obo/GO_0099163) + +- [regulation of synaptic signaling by nitric oxide](http://purl.obolibrary.org/obo/GO_0150045) SubClassOf [regulation of signaling](http://purl.obolibrary.org/obo/GO_0023051) + + + +### regulatory T cell `http://purl.obolibrary.org/obo/CL_0000815` + +#### Added +- [regulatory T cell](http://purl.obolibrary.org/obo/CL_0000815) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### renal afferent arteriole `http://purl.obolibrary.org/obo/UBERON_0004639` +#### Removed +- [renal afferent arteriole](http://purl.obolibrary.org/obo/UBERON_0004639) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteriola glomerularis afferens" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Afferent_arterioles" + +- [renal afferent arteriole](http://purl.obolibrary.org/obo/UBERON_0004639) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "arteriola glomerularis afferens renis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:77042" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [renal afferent arteriole](http://purl.obolibrary.org/obo/UBERON_0004639) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "arteriola glomerularis afferens renis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:77042" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [renal afferent arteriole](http://purl.obolibrary.org/obo/UBERON_0004639) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteriola glomerularis afferens" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Afferent_arterioles" + + +### renal alpha-intercalated cell `http://purl.obolibrary.org/obo/CL_0005011` + +#### Added +- [renal alpha-intercalated cell](http://purl.obolibrary.org/obo/CL_0005011) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### renal artery `http://purl.obolibrary.org/obo/UBERON_0001184` +#### Removed +- [renal artery](http://purl.obolibrary.org/obo/UBERON_0001184) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria renalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Renal_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [renal artery](http://purl.obolibrary.org/obo/UBERON_0001184) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria renalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Renal_artery" + + +### renal beta-intercalated cell `http://purl.obolibrary.org/obo/CL_0002201` + +#### Added +- [renal beta-intercalated cell](http://purl.obolibrary.org/obo/CL_0002201) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### renal collecting system `http://purl.obolibrary.org/obo/UBERON_0004100` +#### Removed +- [renal collecting system](http://purl.obolibrary.org/obo/UBERON_0004100) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tubulus renalis colligens" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Collecting_duct_system" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [renal collecting system](http://purl.obolibrary.org/obo/UBERON_0004100) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tubulus renalis colligens" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Collecting_duct_system" + + +### renal connecting tubule `http://purl.obolibrary.org/obo/UBERON_0005097` +#### Removed +- [renal connecting tubule](http://purl.obolibrary.org/obo/UBERON_0005097) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tubulus renalis arcuatus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Connecting_tubule" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [renal connecting tubule](http://purl.obolibrary.org/obo/UBERON_0005097) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tubulus renalis arcuatus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Connecting_tubule" + + +### renal corpuscle `http://purl.obolibrary.org/obo/UBERON_0001229` +#### Removed +- [renal corpuscle](http://purl.obolibrary.org/obo/UBERON_0001229) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "corpusculum renis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Renal_corpuscle" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [renal corpuscle](http://purl.obolibrary.org/obo/UBERON_0001229) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "corpusculum renale" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [renal corpuscle](http://purl.obolibrary.org/obo/UBERON_0001229) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "corpusculum renale" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [renal corpuscle](http://purl.obolibrary.org/obo/UBERON_0001229) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "corpusculum renis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Renal_corpuscle" + + +### renal efferent arteriole `http://purl.obolibrary.org/obo/UBERON_0004640` +#### Removed +- [renal efferent arteriole](http://purl.obolibrary.org/obo/UBERON_0004640) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteriola glomerularis efferens capsulae renalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Efferent_arteriole" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [renal efferent arteriole](http://purl.obolibrary.org/obo/UBERON_0004640) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "arteriola glomerularis efferens renis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:77043" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [renal efferent arteriole](http://purl.obolibrary.org/obo/UBERON_0004640) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteriola glomerularis efferens capsulae renalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Efferent_arteriole" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [renal efferent arteriole](http://purl.obolibrary.org/obo/UBERON_0004640) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "arteriola glomerularis efferens renis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:77043" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### renal glomerulus `http://purl.obolibrary.org/obo/UBERON_0000074` +#### Removed +- [renal glomerulus](http://purl.obolibrary.org/obo/UBERON_0000074) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "glomerulus renis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Glomerulus" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [renal glomerulus](http://purl.obolibrary.org/obo/UBERON_0000074) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "glomerulus renis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Glomerulus" + + +### renal intercalated cell `http://purl.obolibrary.org/obo/CL_0005010` + +#### Added +- [renal intercalated cell](http://purl.obolibrary.org/obo/CL_0005010) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### renal interlobular vein `http://purl.obolibrary.org/obo/UBERON_0005168` +#### Removed +- [renal interlobular vein](http://purl.obolibrary.org/obo/UBERON_0005168) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "venae interlobulares renis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Interlobular_veins" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [renal interlobular vein](http://purl.obolibrary.org/obo/UBERON_0005168) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "venae interlobulares renis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:71634" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [renal interlobular vein](http://purl.obolibrary.org/obo/UBERON_0005168) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "venae interlobulares renis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Interlobular_veins" + +- [renal interlobular vein](http://purl.obolibrary.org/obo/UBERON_0005168) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "venae interlobulares renis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:71634" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### renal interstitial pericyte `http://purl.obolibrary.org/obo/CL_1001318` + +#### Added +- [renal interstitial pericyte](http://purl.obolibrary.org/obo/CL_1001318) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### renal lobe `http://purl.obolibrary.org/obo/UBERON_0009913` +#### Removed +- [renal lobe](http://purl.obolibrary.org/obo/UBERON_0009913) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "lobi renales" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Renal_lobe" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [renal lobe](http://purl.obolibrary.org/obo/UBERON_0009913) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "lobi renales" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Renal_lobe" + + +### renal lobule `http://purl.obolibrary.org/obo/UBERON_0009914` +#### Removed +- [renal lobule](http://purl.obolibrary.org/obo/UBERON_0009914) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "lobuli corticales renis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Cortical_lobule" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [renal lobule](http://purl.obolibrary.org/obo/UBERON_0009914) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "lobuli corticales renis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Cortical_lobule" + + +### renal medulla `http://purl.obolibrary.org/obo/UBERON_0000362` +#### Removed +- [renal medulla](http://purl.obolibrary.org/obo/UBERON_0000362) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "medulla renalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:74268" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [renal medulla](http://purl.obolibrary.org/obo/UBERON_0000362) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pyramides renales" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:74268" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [renal medulla](http://purl.obolibrary.org/obo/UBERON_0000362) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pyramides renales" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:74268" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [renal medulla](http://purl.obolibrary.org/obo/UBERON_0000362) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "medulla renalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:74268" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### renal pelvis `http://purl.obolibrary.org/obo/UBERON_0001224` +#### Removed +- [renal pelvis](http://purl.obolibrary.org/obo/UBERON_0001224) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "p. renallis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Renal_pelvis" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [renal pelvis](http://purl.obolibrary.org/obo/UBERON_0001224) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "p. renallis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Renal_pelvis" + + +### renal pelvis/ureter `http://purl.obolibrary.org/obo/UBERON_0036295` + +#### Added +- [renal pelvis/ureter](http://purl.obolibrary.org/obo/UBERON_0036295) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [human_reference_atlas](http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas) + +- [renal pelvis/ureter](http://purl.obolibrary.org/obo/UBERON_0036295) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606) + + +### renal principal cell `http://purl.obolibrary.org/obo/CL_0005009` + +#### Added +- [renal principal cell](http://purl.obolibrary.org/obo/CL_0005009) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### renal system `http://purl.obolibrary.org/obo/UBERON_0001008` +#### Removed +- [renal system](http://purl.obolibrary.org/obo/UBERON_0001008) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005056" + +#### Added +- [renal system](http://purl.obolibrary.org/obo/UBERON_0001008) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005056" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### renal vein `http://purl.obolibrary.org/obo/UBERON_0001140` +#### Removed +- [renal vein](http://purl.obolibrary.org/obo/UBERON_0001140) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "venae renales" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Renal_vein" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [renal vein](http://purl.obolibrary.org/obo/UBERON_0001140) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "venae renales" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Renal_vein" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### reproductive gland `http://purl.obolibrary.org/obo/UBERON_0003937` +#### Removed +- [reproductive gland](http://purl.obolibrary.org/obo/UBERON_0003937) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0006162" + - [contributor](http://purl.org/dc/terms/contributor) "https://orcid.org/0000-0003-4423-4370" + +#### Added +- [reproductive gland](http://purl.obolibrary.org/obo/UBERON_0003937) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0006162" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + - [author_id](https://w3id.org/sssom/author_id) [0000-0003-4423-4370](https://orcid.org/0000-0003-4423-4370) + + +### reproductive system `http://purl.obolibrary.org/obo/UBERON_0000990` +#### Removed +- [reproductive system](http://purl.obolibrary.org/obo/UBERON_0000990) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00004857" + +- [reproductive system](http://purl.obolibrary.org/obo/UBERON_0000990) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "systemata genitalia" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Reproductive_system" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [reproductive system](http://purl.obolibrary.org/obo/UBERON_0000990) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606) + +- [reproductive system](http://purl.obolibrary.org/obo/UBERON_0000990) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00004857" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + +- [reproductive system](http://purl.obolibrary.org/obo/UBERON_0000990) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [human_reference_atlas](http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas) + +- [reproductive system](http://purl.obolibrary.org/obo/UBERON_0000990) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D005835" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [LexicalMatching](https://w3id.org/semapv/vocab/LexicalMatching) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + +- [reproductive system](http://purl.obolibrary.org/obo/UBERON_0000990) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "systemata genitalia" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Reproductive_system" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### respiratory basal cell `http://purl.obolibrary.org/obo/CL_0002633` + +#### Added +- [respiratory basal cell](http://purl.obolibrary.org/obo/CL_0002633) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### respiratory bronchiole `http://purl.obolibrary.org/obo/UBERON_0002188` +#### Removed +- [respiratory bronchiole](http://purl.obolibrary.org/obo/UBERON_0002188) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "bronchiolus respiratorii" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Respiratory_bronchiole" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [respiratory bronchiole](http://purl.obolibrary.org/obo/UBERON_0002188) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "bronchiolus respiratorius" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:7412" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [respiratory bronchiole](http://purl.obolibrary.org/obo/UBERON_0002188) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "bronchiolus respiratorii" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Respiratory_bronchiole" + +- [respiratory bronchiole](http://purl.obolibrary.org/obo/UBERON_0002188) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "bronchiolus respiratorius" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:7412" + + +### respiratory epithelial cell `http://purl.obolibrary.org/obo/CL_0002368` + +#### Added +- [respiratory epithelial cell](http://purl.obolibrary.org/obo/CL_0002368) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### respiratory goblet cell `http://purl.obolibrary.org/obo/CL_0002370` + +#### Added +- [respiratory goblet cell](http://purl.obolibrary.org/obo/CL_0002370) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### respiratory hillock cell `http://purl.obolibrary.org/obo/CL_4030023` + +#### Added +- [respiratory hillock cell](http://purl.obolibrary.org/obo/CL_4030023) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### respiratory muscle `http://purl.obolibrary.org/obo/UBERON_0014398` +#### Removed +- [respiratory muscle](http://purl.obolibrary.org/obo/UBERON_0014398) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D012132" + +#### Added +- [respiratory muscle](http://purl.obolibrary.org/obo/UBERON_0014398) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D012132" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [author_id](https://w3id.org/sssom/author_id) [0000-0001-9439-5346](https://orcid.org/0000-0001-9439-5346) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### respiratory segment of nasal mucosa `http://purl.obolibrary.org/obo/UBERON_0015786` +#### Removed +- [respiratory segment of nasal mucosa](http://purl.obolibrary.org/obo/UBERON_0015786) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pars respiratoria tunicae mucosae nasi" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:77198" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [respiratory segment of nasal mucosa](http://purl.obolibrary.org/obo/UBERON_0015786) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pars respiratoria tunicae mucosae nasi" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:77198" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### respiratory system `http://purl.obolibrary.org/obo/UBERON_0001004` +#### Removed +- [respiratory system](http://purl.obolibrary.org/obo/UBERON_0001004) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "systema respiratorium" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Respiratory_system" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [respiratory system](http://purl.obolibrary.org/obo/UBERON_0001004) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "systema respiratorium" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Respiratory_system" + + +### response to nitric oxide `http://purl.obolibrary.org/obo/GO_0071731` +#### Removed +- [response to nitric oxide](http://purl.obolibrary.org/obo/GO_0071731) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0071731" + +- [response to nitric oxide](http://purl.obolibrary.org/obo/GO_0071731) [created by](http://www.geneontology.org/formats/oboInOwl#created_by) "mah" + +- [response to nitric oxide](http://purl.obolibrary.org/obo/GO_0071731) [creation date](http://www.geneontology.org/formats/oboInOwl#creation_date) "2010-03-17T04:03:38Z" + +- [response to nitric oxide](http://purl.obolibrary.org/obo/GO_0071731) [label](http://www.w3.org/2000/01/rdf-schema#label) "response to nitric oxide" + +- [response to nitric oxide](http://purl.obolibrary.org/obo/GO_0071731) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitric oxide stimulus." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:mah" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:yaf" + +- [response to nitric oxide](http://purl.obolibrary.org/obo/GO_0071731) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- Class: [response to nitric oxide](http://purl.obolibrary.org/obo/GO_0071731) + +- [response to nitric oxide](http://purl.obolibrary.org/obo/GO_0071731) EquivalentTo [response to stimulus](http://purl.obolibrary.org/obo/GO_0050896) and ([has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [CHEBI_16480](http://purl.obolibrary.org/obo/CHEBI_16480)) + +- [response to nitric oxide](http://purl.obolibrary.org/obo/GO_0071731) SubClassOf [has primary input](http://purl.obolibrary.org/obo/RO_0004009) some [CHEBI_16480](http://purl.obolibrary.org/obo/CHEBI_16480) + +- [response to nitric oxide](http://purl.obolibrary.org/obo/GO_0071731) SubClassOf [response to stimulus](http://purl.obolibrary.org/obo/GO_0050896) + + + +### response to stimulus `http://purl.obolibrary.org/obo/GO_0050896` +#### Removed +- [response to stimulus](http://purl.obolibrary.org/obo/GO_0050896) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [prokaryote_subset](http://purl.obolibrary.org/obo/go#prokaryote_subset) + +#### Added +- [response to stimulus](http://purl.obolibrary.org/obo/GO_0050896) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_prokaryote](http://purl.obolibrary.org/obo/go#goslim_prokaryote) + + +### reticular cell `http://purl.obolibrary.org/obo/CL_0000432` + +#### Added +- [reticular cell](http://purl.obolibrary.org/obo/CL_0000432) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### reticular layer of dermis `http://purl.obolibrary.org/obo/UBERON_0001993` +#### Removed +- [reticular layer of dermis](http://purl.obolibrary.org/obo/UBERON_0001993) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "stratum reticulare" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Reticular_dermis" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [reticular layer of dermis](http://purl.obolibrary.org/obo/UBERON_0001993) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "stratum reticulare dermis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:64778" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [reticular layer of dermis](http://purl.obolibrary.org/obo/UBERON_0001993) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "stratum reticulare dermis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:64778" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [reticular layer of dermis](http://purl.obolibrary.org/obo/UBERON_0001993) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "stratum reticulare" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Reticular_dermis" + + +### reticulocyte `http://purl.obolibrary.org/obo/CL_0000558` + +#### Added +- [reticulocyte](http://purl.obolibrary.org/obo/CL_0000558) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### retina horizontal cell `http://purl.obolibrary.org/obo/CL_0000745` + +#### Added +- [retina horizontal cell](http://purl.obolibrary.org/obo/CL_0000745) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### retinal bipolar neuron `http://purl.obolibrary.org/obo/CL_0000748` + +#### Added +- [retinal bipolar neuron](http://purl.obolibrary.org/obo/CL_0000748) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### retinal blood vessel endothelial cell `http://purl.obolibrary.org/obo/CL_0002585` + +#### Added +- [retinal blood vessel endothelial cell](http://purl.obolibrary.org/obo/CL_0002585) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### retinal cone cell `http://purl.obolibrary.org/obo/CL_0000573` + +#### Added +- [retinal cone cell](http://purl.obolibrary.org/obo/CL_0000573) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### retinal ganglion cell `http://purl.obolibrary.org/obo/CL_0000740` + +#### Added +- [retinal ganglion cell](http://purl.obolibrary.org/obo/CL_0000740) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### retinal neural layer `http://purl.obolibrary.org/obo/UBERON_0003902` +#### Removed +- [retinal neural layer](http://purl.obolibrary.org/obo/UBERON_0003902) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "stratum nervosum retinae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:58628" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [retinal neural layer](http://purl.obolibrary.org/obo/UBERON_0003902) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "stratum nervosum retinae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:58628" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### retinal pigment epithelial cell `http://purl.obolibrary.org/obo/CL_0002586` + +#### Added +- [retinal pigment epithelial cell](http://purl.obolibrary.org/obo/CL_0002586) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### retinal rod cell `http://purl.obolibrary.org/obo/CL_0000604` + +#### Added +- [retinal rod cell](http://purl.obolibrary.org/obo/CL_0000604) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### retrograde trans-synaptic signaling by nitric oxide `http://purl.obolibrary.org/obo/GO_0098924` +#### Removed +- [retrograde trans-synaptic signaling by nitric oxide](http://purl.obolibrary.org/obo/GO_0098924) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0098924" + +- [retrograde trans-synaptic signaling by nitric oxide](http://purl.obolibrary.org/obo/GO_0098924) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [retrograde trans-synaptic signaling by nitric oxide](http://purl.obolibrary.org/obo/GO_0098924) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by nitric oxide." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:dos" + +- [retrograde trans-synaptic signaling by nitric oxide](http://purl.obolibrary.org/obo/GO_0098924) [label](http://www.w3.org/2000/01/rdf-schema#label) "retrograde trans-synaptic signaling by nitric oxide" + +- [retrograde trans-synaptic signaling by nitric oxide](http://purl.obolibrary.org/obo/GO_0098924) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_synapse](http://purl.obolibrary.org/obo/go#goslim_synapse) + +- Class: [retrograde trans-synaptic signaling by nitric oxide](http://purl.obolibrary.org/obo/GO_0098924) + +- [retrograde trans-synaptic signaling by nitric oxide](http://purl.obolibrary.org/obo/GO_0098924) EquivalentTo [trans-synaptic signaling](http://purl.obolibrary.org/obo/GO_0099537) and ([has start location](http://purl.obolibrary.org/obo/RO_0002231) some [postsynapse](http://purl.obolibrary.org/obo/GO_0098794)) and ([has end location](http://purl.obolibrary.org/obo/RO_0002232) some [presynapse](http://purl.obolibrary.org/obo/GO_0098793)) and ([process has causal agent](http://purl.obolibrary.org/obo/RO_0002608) some [CHEBI_16480](http://purl.obolibrary.org/obo/CHEBI_16480)) + +- [retrograde trans-synaptic signaling by nitric oxide](http://purl.obolibrary.org/obo/GO_0098924) SubClassOf [trans-synaptic signaling by nitric oxide](http://purl.obolibrary.org/obo/GO_0099548) + +- [retrograde trans-synaptic signaling by nitric oxide](http://purl.obolibrary.org/obo/GO_0098924) SubClassOf [retrograde trans-synaptic signaling by soluble gas](http://purl.obolibrary.org/obo/GO_0098923) + + + +### retrograde trans-synaptic signaling by nitric oxide, modulating synaptic transmission `http://purl.obolibrary.org/obo/GO_0098925` +#### Removed +- [retrograde trans-synaptic signaling by nitric oxide, modulating synaptic transmission](http://purl.obolibrary.org/obo/GO_0098925) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_synapse](http://purl.obolibrary.org/obo/go#goslim_synapse) + +- [retrograde trans-synaptic signaling by nitric oxide, modulating synaptic transmission](http://purl.obolibrary.org/obo/GO_0098925) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua." + +- [retrograde trans-synaptic signaling by nitric oxide, modulating synaptic transmission](http://purl.obolibrary.org/obo/GO_0098925) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [retrograde trans-synaptic signaling by nitric oxide, modulating synaptic transmission](http://purl.obolibrary.org/obo/GO_0098925) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0098925" + +- [retrograde trans-synaptic signaling by nitric oxide, modulating synaptic transmission](http://purl.obolibrary.org/obo/GO_0098925) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Modulation of synaptic transmission by cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by nitric oxide." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:dos" + +- [retrograde trans-synaptic signaling by nitric oxide, modulating synaptic transmission](http://purl.obolibrary.org/obo/GO_0098925) [label](http://www.w3.org/2000/01/rdf-schema#label) "retrograde trans-synaptic signaling by nitric oxide, modulating synaptic transmission" + +- Class: [retrograde trans-synaptic signaling by nitric oxide, modulating synaptic transmission](http://purl.obolibrary.org/obo/GO_0098925) + +- [retrograde trans-synaptic signaling by nitric oxide, modulating synaptic transmission](http://purl.obolibrary.org/obo/GO_0098925) EquivalentTo [trans-synaptic signaling](http://purl.obolibrary.org/obo/GO_0099537) and ([regulates](http://purl.obolibrary.org/obo/RO_0002211) some [chemical synaptic transmission](http://purl.obolibrary.org/obo/GO_0007268)) and ([has start location](http://purl.obolibrary.org/obo/RO_0002231) some [postsynapse](http://purl.obolibrary.org/obo/GO_0098794)) and ([has end location](http://purl.obolibrary.org/obo/RO_0002232) some [presynapse](http://purl.obolibrary.org/obo/GO_0098793)) and ([process has causal agent](http://purl.obolibrary.org/obo/RO_0002608) some [CHEBI_16480](http://purl.obolibrary.org/obo/CHEBI_16480)) + +- [retrograde trans-synaptic signaling by nitric oxide, modulating synaptic transmission](http://purl.obolibrary.org/obo/GO_0098925) SubClassOf [trans-synaptic signaling by nitric oxide, modulating synaptic transmission](http://purl.obolibrary.org/obo/GO_0099555) + +- [retrograde trans-synaptic signaling by nitric oxide, modulating synaptic transmission](http://purl.obolibrary.org/obo/GO_0098925) SubClassOf [retrograde trans-synaptic signaling by nitric oxide](http://purl.obolibrary.org/obo/GO_0098924) + + + +### retrograde trans-synaptic signaling by soluble gas `http://purl.obolibrary.org/obo/GO_0098923` +#### Removed +- [retrograde trans-synaptic signaling by soluble gas](http://purl.obolibrary.org/obo/GO_0098923) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by an soluble gas ligand." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:dos" + +- [retrograde trans-synaptic signaling by soluble gas](http://purl.obolibrary.org/obo/GO_0098923) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0098923" + +- [retrograde trans-synaptic signaling by soluble gas](http://purl.obolibrary.org/obo/GO_0098923) [label](http://www.w3.org/2000/01/rdf-schema#label) "retrograde trans-synaptic signaling by soluble gas" + +- [retrograde trans-synaptic signaling by soluble gas](http://purl.obolibrary.org/obo/GO_0098923) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_synapse](http://purl.obolibrary.org/obo/go#goslim_synapse) + +- [retrograde trans-synaptic signaling by soluble gas](http://purl.obolibrary.org/obo/GO_0098923) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- Class: [retrograde trans-synaptic signaling by soluble gas](http://purl.obolibrary.org/obo/GO_0098923) + +- [retrograde trans-synaptic signaling by soluble gas](http://purl.obolibrary.org/obo/GO_0098923) EquivalentTo [trans-synaptic signaling by soluble gas](http://purl.obolibrary.org/obo/GO_0099543) and ([has start location](http://purl.obolibrary.org/obo/RO_0002231) some [postsynapse](http://purl.obolibrary.org/obo/GO_0098794)) and ([has end location](http://purl.obolibrary.org/obo/RO_0002232) some [presynapse](http://purl.obolibrary.org/obo/GO_0098793)) + +- [retrograde trans-synaptic signaling by soluble gas](http://purl.obolibrary.org/obo/GO_0098923) SubClassOf [trans-synaptic signaling by soluble gas](http://purl.obolibrary.org/obo/GO_0099543) + +- [retrograde trans-synaptic signaling by soluble gas](http://purl.obolibrary.org/obo/GO_0098923) SubClassOf [retrograde trans-synaptic signaling](http://purl.obolibrary.org/obo/GO_0098917) + + + +### rib `http://purl.obolibrary.org/obo/UBERON_0002228` + +#### Added +- [rib](http://purl.obolibrary.org/obo/UBERON_0002228) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "VO:0012403" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + - [author_id](https://w3id.org/sssom/author_id) [0000-0003-4423-4370](https://orcid.org/0000-0003-4423-4370) + + +### ribosome `http://purl.obolibrary.org/obo/GO_0005840` +#### Removed +- [ribosome](http://purl.obolibrary.org/obo/GO_0005840) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [prokaryote_subset](http://purl.obolibrary.org/obo/go#prokaryote_subset) + +#### Added +- [ribosome](http://purl.obolibrary.org/obo/GO_0005840) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_prokaryote](http://purl.obolibrary.org/obo/go#goslim_prokaryote) + + +### ribosome biogenesis `http://purl.obolibrary.org/obo/GO_0042254` +#### Removed +- [ribosome biogenesis](http://purl.obolibrary.org/obo/GO_0042254) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [prokaryote_subset](http://purl.obolibrary.org/obo/go#prokaryote_subset) + +#### Added +- [ribosome biogenesis](http://purl.obolibrary.org/obo/GO_0042254) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_prokaryote](http://purl.obolibrary.org/obo/go#goslim_prokaryote) + + +### right adrenal gland `http://purl.obolibrary.org/obo/UBERON_0001233` +#### Removed +- [right adrenal gland](http://purl.obolibrary.org/obo/UBERON_0001233) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "glandula suprarenalis dexter" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [right adrenal gland](http://purl.obolibrary.org/obo/UBERON_0001233) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "glandula suprarenalis dexter" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### right bundle branch `http://purl.obolibrary.org/obo/UBERON_0005987` +#### Removed +- [right bundle branch](http://purl.obolibrary.org/obo/UBERON_0005987) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "crus dextrum fasciculi atrioventricularis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:9486" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [right bundle branch](http://purl.obolibrary.org/obo/UBERON_0005987) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "crus dextrum fasciculi atrioventricularis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:9486" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### right cardiac atrium `http://purl.obolibrary.org/obo/UBERON_0002078` +#### Removed +- [right cardiac atrium](http://purl.obolibrary.org/obo/UBERON_0002078) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "atrium dextrum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Right_atrium" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [right cardiac atrium](http://purl.obolibrary.org/obo/UBERON_0002078) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "atrium dextrum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Right_atrium" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### right crus of diaphragm `http://purl.obolibrary.org/obo/UBERON_0014766` + +#### Added +- [right crus of diaphragm](http://purl.obolibrary.org/obo/UBERON_0014766) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "right crus of diaphragm" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:58286" + +- [right crus of diaphragm](http://purl.obolibrary.org/obo/UBERON_0014766) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "crus dextrum diaphragmatis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:58286" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [right crus of diaphragm](http://purl.obolibrary.org/obo/UBERON_0014766) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "uberon" + +- [right crus of diaphragm](http://purl.obolibrary.org/obo/UBERON_0014766) [UBPROP_0000006](http://purl.obolibrary.org/obo/UBPROP_0000006) "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + +- [right crus of diaphragm](http://purl.obolibrary.org/obo/UBERON_0014766) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "SCTID:362690009" + +- [right crus of diaphragm](http://purl.obolibrary.org/obo/UBERON_0014766) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "crus dextrum (Diaphragma)" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:58286" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [right crus of diaphragm](http://purl.obolibrary.org/obo/UBERON_0014766) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "external sphincter of esophagus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:58286" + +- [right crus of diaphragm](http://purl.obolibrary.org/obo/UBERON_0014766) [label](http://www.w3.org/2000/01/rdf-schema#label) "right crus of diaphragm" + +- [right crus of diaphragm](http://purl.obolibrary.org/obo/UBERON_0014766) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A crus of diaphragm that is in_the_right_side_of a diaphragm." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "OBOL:automatic" + +- [right crus of diaphragm](http://purl.obolibrary.org/obo/UBERON_0014766) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "right crus of lumbar part of diaphragm" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:58286" + +- [right crus of diaphragm](http://purl.obolibrary.org/obo/UBERON_0014766) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:58286" + +- [right crus of diaphragm](http://purl.obolibrary.org/obo/UBERON_0014766) [id](http://www.geneontology.org/formats/oboInOwl#id) "UBERON:0014766" + +- Class: [right crus of diaphragm](http://purl.obolibrary.org/obo/UBERON_0014766) + +- [right crus of diaphragm](http://purl.obolibrary.org/obo/UBERON_0014766) EquivalentTo [crus of diaphragm](http://purl.obolibrary.org/obo/UBERON_0014765) and ([in right side of](http://purl.obolibrary.org/obo/BSPO_0000121) some [diaphragm](http://purl.obolibrary.org/obo/UBERON_0001103)) + +- [right crus of diaphragm](http://purl.obolibrary.org/obo/UBERON_0014766) SubClassOf [crus of diaphragm](http://purl.obolibrary.org/obo/UBERON_0014765) + +- [right crus of diaphragm](http://purl.obolibrary.org/obo/UBERON_0014766) SubClassOf [in right side of](http://purl.obolibrary.org/obo/BSPO_0000121) some [diaphragm](http://purl.obolibrary.org/obo/UBERON_0001103) + + +### right hepatic artery `http://purl.obolibrary.org/obo/UBERON_0015482` +#### Removed +- [right hepatic artery](http://purl.obolibrary.org/obo/UBERON_0015482) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ramus dexter (arteria hepatica propria)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:14778" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [right hepatic artery](http://purl.obolibrary.org/obo/UBERON_0015482) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ramus dexter (arteria hepatica propria)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:14778" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### right hepatic duct `http://purl.obolibrary.org/obo/UBERON_0001176` +#### Removed +- [right hepatic duct](http://purl.obolibrary.org/obo/UBERON_0001176) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ductus hepaticus dexter" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [right hepatic duct](http://purl.obolibrary.org/obo/UBERON_0001176) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ductus hepaticus dexter" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### right lobe of liver `http://purl.obolibrary.org/obo/UBERON_0001114` +#### Removed +- [right lobe of liver](http://purl.obolibrary.org/obo/UBERON_0001114) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "lobus hepatis dexter" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Right_lobe_of_liver" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [right lobe of liver](http://purl.obolibrary.org/obo/UBERON_0001114) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lobus hepaticus dexter" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [right lobe of liver](http://purl.obolibrary.org/obo/UBERON_0001114) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "lobus hepatis dexter" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Right_lobe_of_liver" + +- [right lobe of liver](http://purl.obolibrary.org/obo/UBERON_0001114) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lobus hepaticus dexter" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### right pulmonary artery `http://purl.obolibrary.org/obo/UBERON_0001651` +#### Removed +- [right pulmonary artery](http://purl.obolibrary.org/obo/UBERON_0001651) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria pulmonalis dextra" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Right_pulmonary_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [right pulmonary artery](http://purl.obolibrary.org/obo/UBERON_0001651) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria pulmonalis dextra" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Right_pulmonary_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### right subclavian artery `http://purl.obolibrary.org/obo/UBERON_0001534` +#### Removed +- [right subclavian artery](http://purl.obolibrary.org/obo/UBERON_0001534) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "arteria subclavia dextra" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:3953" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [right subclavian artery](http://purl.obolibrary.org/obo/UBERON_0001534) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "arteria subclavia dextra" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:3953" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### right ventricular trabecular myocardium `http://purl.obolibrary.org/obo/UBERON_0005066` +#### Removed +- [right ventricular trabecular myocardium](http://purl.obolibrary.org/obo/UBERON_0005066) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GO:0003227" + +#### Added +- [right ventricular trabecular myocardium](http://purl.obolibrary.org/obo/UBERON_0005066) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Missing definition for term UBERON:0005066. Please replace it using linked reference." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GO:0003227" + + +### rod bipolar cell `http://purl.obolibrary.org/obo/CL_0000751` + +#### Added +- [rod bipolar cell](http://purl.obolibrary.org/obo/CL_0000751) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### saccule of membranous labyrinth `http://purl.obolibrary.org/obo/UBERON_0001854` +#### Removed +- [saccule of membranous labyrinth](http://purl.obolibrary.org/obo/UBERON_0001854) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "sacculus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Saccule" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [saccule of membranous labyrinth](http://purl.obolibrary.org/obo/UBERON_0001854) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "sacculus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Saccule" + + +### saliva `http://purl.obolibrary.org/obo/UBERON_0001836` +#### Removed +- [saliva](http://purl.obolibrary.org/obo/UBERON_0001836) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "saliva molecularis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Saliva" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [saliva](http://purl.obolibrary.org/obo/UBERON_0001836) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "saliva atomaris" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Saliva" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [saliva](http://purl.obolibrary.org/obo/UBERON_0001836) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "sailva normalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Saliva" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [saliva](http://purl.obolibrary.org/obo/UBERON_0001836) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "saliva molecularis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Saliva" + +- [saliva](http://purl.obolibrary.org/obo/UBERON_0001836) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "sailva normalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Saliva" + +- [saliva](http://purl.obolibrary.org/obo/UBERON_0001836) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "saliva atomaris" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Saliva" + + +### saliva-secreting gland `http://purl.obolibrary.org/obo/UBERON_0001044` +#### Removed +- [saliva-secreting gland](http://purl.obolibrary.org/obo/UBERON_0001044) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "glandulae salivariae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Salivary_gland" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [saliva-secreting gland](http://purl.obolibrary.org/obo/UBERON_0001044) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005382" + +#### Added +- [saliva-secreting gland](http://purl.obolibrary.org/obo/UBERON_0001044) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005382" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + +- [saliva-secreting gland](http://purl.obolibrary.org/obo/UBERON_0001044) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "glandulae salivariae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Salivary_gland" + + +### salivary gland cell `http://purl.obolibrary.org/obo/CL_0009005` + +#### Added +- [salivary gland cell](http://purl.obolibrary.org/obo/CL_0009005) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### salivatory nucleus `http://purl.obolibrary.org/obo/UBERON_0004133` +#### Removed +- [salivatory nucleus](http://purl.obolibrary.org/obo/UBERON_0004133) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GO:0021751" + +#### Added +- [salivatory nucleus](http://purl.obolibrary.org/obo/UBERON_0004133) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Missing definition for term UBERON:0004133. Please replace it using linked reference." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GO:0021751" + + +### scala media `http://purl.obolibrary.org/obo/UBERON_0002295` + +#### Added +- [scala media](http://purl.obolibrary.org/obo/UBERON_0002295) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D003053" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [LexicalMatching](https://w3id.org/semapv/vocab/LexicalMatching) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### scalp `http://purl.obolibrary.org/obo/UBERON_0000403` +#### Removed +- [scalp](http://purl.obolibrary.org/obo/UBERON_0000403) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "scalpus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Scalp" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [scalp](http://purl.obolibrary.org/obo/UBERON_0000403) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "scalpus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Scalp" + + +### sciatic nerve `http://purl.obolibrary.org/obo/UBERON_0001322` +#### Removed +- [sciatic nerve](http://purl.obolibrary.org/obo/UBERON_0001322) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nervus ischiadicus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Sciatic_nerve" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0001221" + +#### Added +- [sciatic nerve](http://purl.obolibrary.org/obo/UBERON_0001322) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nervus ischiadicus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Sciatic_nerve" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0001221" + + +### sclerotome `http://purl.obolibrary.org/obo/UBERON_0003089` +#### Removed +- [sclerotome](http://purl.obolibrary.org/obo/UBERON_0003089) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "sclerotomus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Sclerotome" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [sclerotome](http://purl.obolibrary.org/obo/UBERON_0003089) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0006255" + - [contributor](http://purl.org/dc/terms/contributor) "https://orcid.org/0000-0003-4423-4370" + +#### Added +- [sclerotome](http://purl.obolibrary.org/obo/UBERON_0003089) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0006255" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + - [author_id](https://w3id.org/sssom/author_id) [0000-0003-4423-4370](https://orcid.org/0000-0003-4423-4370) + +- [sclerotome](http://purl.obolibrary.org/obo/UBERON_0003089) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "sclerotomus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Sclerotome" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### sebaceous gland `http://purl.obolibrary.org/obo/UBERON_0001821` +#### Removed +- [sebaceous gland](http://purl.obolibrary.org/obo/UBERON_0001821) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "glandula sebacea" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Sebaceous_gland" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [sebaceous gland](http://purl.obolibrary.org/obo/UBERON_0001821) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "glandula sebacea" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Sebaceous_gland" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### sebaceous gland cell `http://purl.obolibrary.org/obo/CL_2000021` + +#### Added +- [sebaceous gland cell](http://purl.obolibrary.org/obo/CL_2000021) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### second-messenger-mediated signaling `http://purl.obolibrary.org/obo/GO_0019932` +#### Removed +- [second-messenger-mediated signaling](http://purl.obolibrary.org/obo/GO_0019932) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "second-messenger-mediated signalling" + +- [second-messenger-mediated signaling](http://purl.obolibrary.org/obo/GO_0019932) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "second messenger-mediated signalling" + +- [second-messenger-mediated signaling](http://purl.obolibrary.org/obo/GO_0019932) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "second messenger mediated signalling" + +- [second-messenger-mediated signaling](http://purl.obolibrary.org/obo/GO_0019932) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0019932" + +- [second-messenger-mediated signaling](http://purl.obolibrary.org/obo/GO_0019932) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [second-messenger-mediated signaling](http://purl.obolibrary.org/obo/GO_0019932) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "second messenger-mediated signaling" + +- [second-messenger-mediated signaling](http://purl.obolibrary.org/obo/GO_0019932) [label](http://www.w3.org/2000/01/rdf-schema#label) "second-messenger-mediated signaling" + +- [second-messenger-mediated signaling](http://purl.obolibrary.org/obo/GO_0019932) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Any intracellular signal transduction in which the signal is passed on within the cell via a second messenger; a small molecule or ion that can be quickly generated or released from intracellular stores, and can diffuse within the cell. Second-messenger signaling includes production or release of the second messenger, and effectors downstream of the second messenger that further transmit the signal within the cell." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Second_messenger_system" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:15221855" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:signaling" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0815316194" + +- [second-messenger-mediated signaling](http://purl.obolibrary.org/obo/GO_0019932) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "second-messenger-mediated signal transduction" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:signaling" + +- [second-messenger-mediated signaling](http://purl.obolibrary.org/obo/GO_0019932) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "second messenger mediated signaling" + +- Class: [second-messenger-mediated signaling](http://purl.obolibrary.org/obo/GO_0019932) + +- [second-messenger-mediated signaling](http://purl.obolibrary.org/obo/GO_0019932) SubClassOf [intracellular signal transduction](http://purl.obolibrary.org/obo/GO_0035556) + + + +### secondary lens fiber `http://purl.obolibrary.org/obo/CL_0002225` + +#### Added +- [secondary lens fiber](http://purl.obolibrary.org/obo/CL_0002225) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### secondary pulmonary lobule `http://purl.obolibrary.org/obo/UBERON_0010369` +#### Removed +- [secondary pulmonary lobule](http://purl.obolibrary.org/obo/UBERON_0010369) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lobulus pulmonis secondarius" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:7414" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [secondary pulmonary lobule](http://purl.obolibrary.org/obo/UBERON_0010369) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lobulus pulmonis secondarius" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:7414" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### secretory cell `http://purl.obolibrary.org/obo/CL_0000151` + +#### Added +- [secretory cell](http://purl.obolibrary.org/obo/CL_0000151) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### segment of manus `http://purl.obolibrary.org/obo/UBERON_0005451` +#### Removed +- [segment of manus](http://purl.obolibrary.org/obo/UBERON_0005451) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regio manus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [segment of manus](http://purl.obolibrary.org/obo/UBERON_0005451) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regio manus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### segment of pes `http://purl.obolibrary.org/obo/UBERON_0005445` +#### Removed +- [segment of pes](http://purl.obolibrary.org/obo/UBERON_0005445) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regio pedis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:24993" + +#### Added +- [segment of pes](http://purl.obolibrary.org/obo/UBERON_0005445) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "regio pedis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:24993" + + +### semicircular canal `http://purl.obolibrary.org/obo/UBERON_0001840` +#### Removed +- [semicircular canal](http://purl.obolibrary.org/obo/UBERON_0001840) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "canalis semicircularis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Semicircular_canal" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [semicircular canal](http://purl.obolibrary.org/obo/UBERON_0001840) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "canalis semicircularis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Semicircular_canal" + + +### semicircular canal ampulla `http://purl.obolibrary.org/obo/UBERON_0004043` +#### Removed +- [semicircular canal ampulla](http://purl.obolibrary.org/obo/UBERON_0004043) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ampullae osseae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Osseous_ampullae" + +#### Added +- [semicircular canal ampulla](http://purl.obolibrary.org/obo/UBERON_0004043) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ampullae osseae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Osseous_ampullae" + + +### semicircular duct `http://purl.obolibrary.org/obo/UBERON_0001856` +#### Removed +- [semicircular duct](http://purl.obolibrary.org/obo/UBERON_0001856) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D054776" + +#### Added +- [semicircular duct](http://purl.obolibrary.org/obo/UBERON_0001856) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D054776" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [author_id](https://w3id.org/sssom/author_id) [0000-0001-9439-5346](https://orcid.org/0000-0001-9439-5346) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### seminal fluid secreting gland `http://purl.obolibrary.org/obo/UBERON_0006868` +#### Removed +- [seminal fluid secreting gland](http://purl.obolibrary.org/obo/UBERON_0006868) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00004958" + +#### Added +- [seminal fluid secreting gland](http://purl.obolibrary.org/obo/UBERON_0006868) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00004958" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### seminal vesicle `http://purl.obolibrary.org/obo/UBERON_0000998` +#### Removed +- [seminal vesicle](http://purl.obolibrary.org/obo/UBERON_0000998) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vesiculae seminales" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Seminal_vesicle" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [seminal vesicle](http://purl.obolibrary.org/obo/UBERON_0000998) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vesiculae seminales" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Seminal_vesicle" + + +### seminal vesicle glandular cell `http://purl.obolibrary.org/obo/CL_1001597` + +#### Added +- [seminal vesicle glandular cell](http://purl.obolibrary.org/obo/CL_1001597) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### seminiferous tubule of testis `http://purl.obolibrary.org/obo/UBERON_0001343` +#### Removed +- [seminiferous tubule of testis](http://purl.obolibrary.org/obo/UBERON_0001343) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tubuli seminiferi" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Seminiferous_tubule" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [seminiferous tubule of testis](http://purl.obolibrary.org/obo/UBERON_0001343) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tubuli seminiferi" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Seminiferous_tubule" + + +### sense organ `http://purl.obolibrary.org/obo/UBERON_0000020` +#### Removed +- [sense organ](http://purl.obolibrary.org/obo/UBERON_0000020) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005155" + +#### Added +- [sense organ](http://purl.obolibrary.org/obo/UBERON_0000020) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005155" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### sensory ganglion `http://purl.obolibrary.org/obo/UBERON_0001800` +#### Removed +- [sensory ganglion](http://purl.obolibrary.org/obo/UBERON_0001800) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ganglion sensorium" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [sensory ganglion](http://purl.obolibrary.org/obo/UBERON_0001800) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ganglion sensorium" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### sensory nerve `http://purl.obolibrary.org/obo/UBERON_0001027` +#### Removed +- [sensory nerve](http://purl.obolibrary.org/obo/UBERON_0001027) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005136" + +- [sensory nerve](http://purl.obolibrary.org/obo/UBERON_0001027) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nervus sensorius" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Sensory_nerve" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [sensory nerve](http://purl.obolibrary.org/obo/UBERON_0001027) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005136" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + +- [sensory nerve](http://purl.obolibrary.org/obo/UBERON_0001027) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nervus sensorius" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Sensory_nerve" + + +### sensory system `http://purl.obolibrary.org/obo/UBERON_0001032` +#### Removed +- [sensory system](http://purl.obolibrary.org/obo/UBERON_0001032) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007692" + +- [sensory system](http://purl.obolibrary.org/obo/UBERON_0001032) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "organa sensuum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Sensory_system" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [sensory system](http://purl.obolibrary.org/obo/UBERON_0001032) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "organa sensuum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:75259" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [sensory system](http://purl.obolibrary.org/obo/UBERON_0001032) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "organa sensuum" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:75259" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [sensory system](http://purl.obolibrary.org/obo/UBERON_0001032) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007692" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + +- [sensory system](http://purl.obolibrary.org/obo/UBERON_0001032) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "organa sensuum" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Sensory_system" + + +### septal nuclear complex `http://purl.obolibrary.org/obo/UBERON_0002663` +#### Removed +- [septal nuclear complex](http://purl.obolibrary.org/obo/UBERON_0002663) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nuclei septales" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Septal_nuclei" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [septal nuclear complex](http://purl.obolibrary.org/obo/UBERON_0002663) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nuclei septales" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Septal_nuclei" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### septum of telencephalon `http://purl.obolibrary.org/obo/UBERON_0000446` +#### Removed +- [septum of telencephalon](http://purl.obolibrary.org/obo/UBERON_0000446) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "massa praecommissuralis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:255" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [septum of telencephalon](http://purl.obolibrary.org/obo/UBERON_0000446) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "septum pellucidum (BNA,PNA)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:255" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [septum of telencephalon](http://purl.obolibrary.org/obo/UBERON_0000446) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "septum telencephali" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:255" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [septum of telencephalon](http://purl.obolibrary.org/obo/UBERON_0000446) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "area septalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:61842" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [septum of telencephalon](http://purl.obolibrary.org/obo/UBERON_0000446) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "area septalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:61842" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [septum of telencephalon](http://purl.obolibrary.org/obo/UBERON_0000446) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "massa praecommissuralis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:255" + +- [septum of telencephalon](http://purl.obolibrary.org/obo/UBERON_0000446) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "septum pellucidum (BNA,PNA)" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:255" + +- [septum of telencephalon](http://purl.obolibrary.org/obo/UBERON_0000446) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "septum telencephali" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:255" + + +### serosa of esophagus `http://purl.obolibrary.org/obo/UBERON_0001975` +#### Removed +- [serosa of esophagus](http://purl.obolibrary.org/obo/UBERON_0001975) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica serosa oesophageae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:63057" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [serosa of esophagus](http://purl.obolibrary.org/obo/UBERON_0001975) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica serosa oesophageae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:63057" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### serosa of large intestine `http://purl.obolibrary.org/obo/UBERON_0001209` +#### Removed +- [serosa of large intestine](http://purl.obolibrary.org/obo/UBERON_0001209) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica serosa intestini crassi" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:14975" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [serosa of large intestine](http://purl.obolibrary.org/obo/UBERON_0001209) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica serosa intestini crassi" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:14975" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### serosa of small intestine `http://purl.obolibrary.org/obo/UBERON_0001206` +#### Removed +- [serosa of small intestine](http://purl.obolibrary.org/obo/UBERON_0001206) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica serosa intestini tenuis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:14938" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [serosa of small intestine](http://purl.obolibrary.org/obo/UBERON_0001206) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica serosa intestini tenuis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:14938" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### serosa of stomach `http://purl.obolibrary.org/obo/UBERON_0001201` +#### Removed +- [serosa of stomach](http://purl.obolibrary.org/obo/UBERON_0001201) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica serosa gastricae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:14914" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [serosa of stomach](http://purl.obolibrary.org/obo/UBERON_0001201) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica serosa gastricae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:14914" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### serosa of urinary bladder `http://purl.obolibrary.org/obo/UBERON_0001260` +#### Removed +- [serosa of urinary bladder](http://purl.obolibrary.org/obo/UBERON_0001260) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica serosa (vesica urinaria)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:15932" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [serosa of urinary bladder](http://purl.obolibrary.org/obo/UBERON_0001260) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica serosa vesicae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:15932" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [serosa of urinary bladder](http://purl.obolibrary.org/obo/UBERON_0001260) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica serosa (vesica urinaria)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:15932" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [serosa of urinary bladder](http://purl.obolibrary.org/obo/UBERON_0001260) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica serosa vesicae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:15932" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### serosa of uterus `http://purl.obolibrary.org/obo/UBERON_0001297` +#### Removed +- [serosa of uterus](http://purl.obolibrary.org/obo/UBERON_0001297) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica serosa uteri" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:17744" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [serosa of uterus](http://purl.obolibrary.org/obo/UBERON_0001297) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica serosa uteri" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:17744" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### serous cell of epithelium of bronchus `http://purl.obolibrary.org/obo/CL_1000331` + +#### Added +- [serous cell of epithelium of bronchus](http://purl.obolibrary.org/obo/CL_1000331) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### serous cell of epithelium of trachea `http://purl.obolibrary.org/obo/CL_1000330` + +#### Added +- [serous cell of epithelium of trachea](http://purl.obolibrary.org/obo/CL_1000330) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### serous membrane `http://purl.obolibrary.org/obo/UBERON_0000042` +#### Removed +- [serous membrane](http://purl.obolibrary.org/obo/UBERON_0000042) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica serosa" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:9581" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [serous membrane](http://purl.obolibrary.org/obo/UBERON_0000042) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica serosa" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:9581" + + +### serous pericardium `http://purl.obolibrary.org/obo/UBERON_0002357` +#### Removed +- [serous pericardium](http://purl.obolibrary.org/obo/UBERON_0002357) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "pericardium serosum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Serous_pericardium" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [serous pericardium](http://purl.obolibrary.org/obo/UBERON_0002357) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "pericardium serosum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Serous_pericardium" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### serous secreting cell `http://purl.obolibrary.org/obo/CL_0000313` + +#### Added +- [serous secreting cell](http://purl.obolibrary.org/obo/CL_0000313) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### serratus ventralis `http://purl.obolibrary.org/obo/UBERON_0001125` +#### Removed +- [serratus ventralis](http://purl.obolibrary.org/obo/UBERON_0001125) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "serratus lateralis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Serratus_anterior_muscle" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [serratus ventralis](http://purl.obolibrary.org/obo/UBERON_0001125) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "musculus serratus anterior" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Serratus_anterior_muscle" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [serratus ventralis](http://purl.obolibrary.org/obo/UBERON_0001125) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "musculus serratus anterior" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Serratus_anterior_muscle" + +- [serratus ventralis](http://purl.obolibrary.org/obo/UBERON_0001125) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "serratus lateralis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Serratus_anterior_muscle" + + +### sesamoid bone `http://purl.obolibrary.org/obo/UBERON_0001479` +#### Removed +- [sesamoid bone](http://purl.obolibrary.org/obo/UBERON_0001479) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ossa sesamoidea" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Sesamoid_bone" + +#### Added +- [sesamoid bone](http://purl.obolibrary.org/obo/UBERON_0001479) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ossa sesamoidea" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Sesamoid_bone" + + +### set of lower jaw teeth `http://purl.obolibrary.org/obo/UBERON_0009679` +#### Removed +- [set of lower jaw teeth](http://purl.obolibrary.org/obo/UBERON_0009679) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "arcus dentalis inferior" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [set of lower jaw teeth](http://purl.obolibrary.org/obo/UBERON_0009679) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "arcus dentalis inferior" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### set of upper jaw teeth `http://purl.obolibrary.org/obo/UBERON_0009680` +#### Removed +- [set of upper jaw teeth](http://purl.obolibrary.org/obo/UBERON_0009680) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "arcus dentalis superior" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [set of upper jaw teeth](http://purl.obolibrary.org/obo/UBERON_0009680) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "arcus dentalis superior" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### shoulder `http://purl.obolibrary.org/obo/UBERON_0001467` +#### Removed +- [shoulder](http://purl.obolibrary.org/obo/UBERON_0001467) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "articulatio humeri" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Shoulder" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [shoulder](http://purl.obolibrary.org/obo/UBERON_0001467) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "articulatio humeri" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Shoulder" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### shoulder joint `http://purl.obolibrary.org/obo/UBERON_0016884` +#### Removed +- [shoulder joint](http://purl.obolibrary.org/obo/UBERON_0016884) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D012785" + +#### Added +- [shoulder joint](http://purl.obolibrary.org/obo/UBERON_0016884) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D012785" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [author_id](https://w3id.org/sssom/author_id) [0000-0001-9439-5346](https://orcid.org/0000-0001-9439-5346) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### sigmoid colon `http://purl.obolibrary.org/obo/UBERON_0001159` +#### Removed +- [sigmoid colon](http://purl.obolibrary.org/obo/UBERON_0001159) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "colon sigmoideum" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Sigmoid_colon" + +#### Added +- [sigmoid colon](http://purl.obolibrary.org/obo/UBERON_0001159) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "colon sigmoideum" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Sigmoid_colon" + + +### signaling `http://purl.obolibrary.org/obo/GO_0023052` +#### Removed +- [signaling](http://purl.obolibrary.org/obo/GO_0023052) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [prokaryote_subset](http://purl.obolibrary.org/obo/go#prokaryote_subset) + +#### Added +- [signaling](http://purl.obolibrary.org/obo/GO_0023052) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_prokaryote](http://purl.obolibrary.org/obo/go#goslim_prokaryote) + + +### simple columnar epithelium `http://purl.obolibrary.org/obo/UBERON_0000485` +#### Removed +- [simple columnar epithelium](http://purl.obolibrary.org/obo/UBERON_0000485) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007027" + +#### Added +- [simple columnar epithelium](http://purl.obolibrary.org/obo/UBERON_0000485) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007027" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### sinoatrial node `http://purl.obolibrary.org/obo/UBERON_0002351` +#### Removed +- [sinoatrial node](http://purl.obolibrary.org/obo/UBERON_0002351) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nodus sinuatrialis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Sinoatrial_node" + +- [sinoatrial node](http://purl.obolibrary.org/obo/UBERON_0002351) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nodus sinuatrialis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:9477" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [sinoatrial node](http://purl.obolibrary.org/obo/UBERON_0002351) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nodus sinuatrialis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Sinoatrial_node" + +- [sinoatrial node](http://purl.obolibrary.org/obo/UBERON_0002351) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nodus sinuatrialis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:9477" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### sinus venosus `http://purl.obolibrary.org/obo/UBERON_0002063` +#### Removed +- [sinus venosus](http://purl.obolibrary.org/obo/UBERON_0002063) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "sinus venosus cordis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Sinus_venosus" + +#### Added +- [sinus venosus](http://purl.obolibrary.org/obo/UBERON_0002063) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "sinus venosus cordis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Sinus_venosus" + + +### skeletal muscle fiber `http://purl.obolibrary.org/obo/CL_0008002` + +#### Added +- [skeletal muscle fiber](http://purl.obolibrary.org/obo/CL_0008002) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### skeletal muscle fibroblast `http://purl.obolibrary.org/obo/CL_0011027` + +#### Added +- [skeletal muscle fibroblast](http://purl.obolibrary.org/obo/CL_0011027) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### skeletal muscle organ, vertebrate `http://purl.obolibrary.org/obo/UBERON_0014892` + +#### Added +- [skeletal muscle organ, vertebrate](http://purl.obolibrary.org/obo/UBERON_0014892) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [human_reference_atlas](http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas) + +- [skeletal muscle organ, vertebrate](http://purl.obolibrary.org/obo/UBERON_0014892) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606) + + +### skeletal muscle satellite cell `http://purl.obolibrary.org/obo/CL_0000594` + +#### Added +- [skeletal muscle satellite cell](http://purl.obolibrary.org/obo/CL_0000594) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### skeletal muscle satellite stem cell `http://purl.obolibrary.org/obo/CL_0008011` + +#### Added +- [skeletal muscle satellite stem cell](http://purl.obolibrary.org/obo/CL_0008011) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### skeletal musculature `http://purl.obolibrary.org/obo/UBERON_0018254` + +#### Added +- [skeletal musculature](http://purl.obolibrary.org/obo/UBERON_0018254) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606) + +- [skeletal musculature](http://purl.obolibrary.org/obo/UBERON_0018254) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [human_reference_atlas](http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas) + + +### skeletal musculature of head `http://purl.obolibrary.org/obo/UBERON_0004461` +#### Removed +- [skeletal musculature of head](http://purl.obolibrary.org/obo/UBERON_0004461) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "musculi capitis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:71287" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [skeletal musculature of head](http://purl.obolibrary.org/obo/UBERON_0004461) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "musculi capitis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:71287" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### skeleton of manus `http://purl.obolibrary.org/obo/UBERON_0001442` +#### Removed +- [skeleton of manus](http://purl.obolibrary.org/obo/UBERON_0001442) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ossa manus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:24159" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [skeleton of manus](http://purl.obolibrary.org/obo/UBERON_0001442) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ossa manus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:24159" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### skin fibroblast `http://purl.obolibrary.org/obo/CL_0002620` + +#### Added +- [skin fibroblast](http://purl.obolibrary.org/obo/CL_0002620) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### skin gland `http://purl.obolibrary.org/obo/UBERON_0002419` +#### Removed +- [skin gland](http://purl.obolibrary.org/obo/UBERON_0002419) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "glandulae cutis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:71878" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [skin gland](http://purl.obolibrary.org/obo/UBERON_0002419) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "glandulae cutis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:71878" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### skin of trunk `http://purl.obolibrary.org/obo/UBERON_0001085` +#### Removed +- [skin of trunk](http://purl.obolibrary.org/obo/UBERON_0001085) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [human_reference_atlas](http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas) + +- [skin of trunk](http://purl.obolibrary.org/obo/UBERON_0001085) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606) + + + +### slow muscle cell `http://purl.obolibrary.org/obo/CL_0000189` + +#### Added +- [slow muscle cell](http://purl.obolibrary.org/obo/CL_0000189) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### small intestine `http://purl.obolibrary.org/obo/UBERON_0002108` +#### Removed +- [small intestine](http://purl.obolibrary.org/obo/UBERON_0002108) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "intestinum tenue" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0000651" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Small_intestine" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [small intestine](http://purl.obolibrary.org/obo/UBERON_0002108) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "intestinum tenue" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0000651" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Small_intestine" + + +### small intestine Peyer's patch `http://purl.obolibrary.org/obo/UBERON_0003454` +#### Removed +- [small intestine Peyer's patch](http://purl.obolibrary.org/obo/UBERON_0003454) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "noduli lymphoidei aggregati intestini tenuis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:76466" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [small intestine Peyer's patch](http://purl.obolibrary.org/obo/UBERON_0003454) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "noduli lymphoidei aggregati intestini tenuis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:76466" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### small intestine goblet cell `http://purl.obolibrary.org/obo/CL_1000495` + +#### Added +- [small intestine goblet cell](http://purl.obolibrary.org/obo/CL_1000495) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### small intestine smooth muscle circular layer `http://purl.obolibrary.org/obo/UBERON_0012401` +#### Removed +- [small intestine smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_0012401) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "stratum circulare tunicae muscularis intestini tenuis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:14935" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [small intestine smooth muscle circular layer](http://purl.obolibrary.org/obo/UBERON_0012401) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "stratum circulare tunicae muscularis intestini tenuis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:14935" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### small intestine smooth muscle longitudinal layer `http://purl.obolibrary.org/obo/UBERON_0012402` +#### Removed +- [small intestine smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/UBERON_0012402) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "stratum longitudinale tunicae muscularis intestini tenuis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:14936" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [small intestine smooth muscle longitudinal layer](http://purl.obolibrary.org/obo/UBERON_0012402) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "stratum longitudinale tunicae muscularis intestini tenuis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:14936" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### small molecule biosynthetic process `http://purl.obolibrary.org/obo/GO_0044283` +#### Removed +- [small molecule biosynthetic process](http://purl.obolibrary.org/obo/GO_0044283) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [prokaryote_subset](http://purl.obolibrary.org/obo/go#prokaryote_subset) + +#### Added +- [small molecule biosynthetic process](http://purl.obolibrary.org/obo/GO_0044283) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_prokaryote](http://purl.obolibrary.org/obo/go#goslim_prokaryote) + + +### small pre-B-II cell `http://purl.obolibrary.org/obo/CL_0000954` + +#### Added +- [small pre-B-II cell](http://purl.obolibrary.org/obo/CL_0000954) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### small saphenous vein `http://purl.obolibrary.org/obo/UBERON_0001547` +#### Removed +- [small saphenous vein](http://purl.obolibrary.org/obo/UBERON_0001547) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "vena saphena parva" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Small_saphenous_vein" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [small saphenous vein](http://purl.obolibrary.org/obo/UBERON_0001547) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "vena saphena parva" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Small_saphenous_vein" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### smooth muscle cell `http://purl.obolibrary.org/obo/CL_0000192` + +#### Added +- [smooth muscle cell](http://purl.obolibrary.org/obo/CL_0000192) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### smooth muscle cell of large intestine `http://purl.obolibrary.org/obo/CL_1000279` + +#### Added +- [smooth muscle cell of large intestine](http://purl.obolibrary.org/obo/CL_1000279) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### smooth muscle cell of prostate `http://purl.obolibrary.org/obo/CL_1000487` + +#### Added +- [smooth muscle cell of prostate](http://purl.obolibrary.org/obo/CL_1000487) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### smooth muscle cell of small intestine `http://purl.obolibrary.org/obo/CL_1000275` + +#### Added +- [smooth muscle cell of small intestine](http://purl.obolibrary.org/obo/CL_1000275) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### smooth muscle cell of sphincter of pupil `http://purl.obolibrary.org/obo/CL_0002243` + +#### Added +- [smooth muscle cell of sphincter of pupil](http://purl.obolibrary.org/obo/CL_0002243) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### smooth muscle cell of the pulmonary artery `http://purl.obolibrary.org/obo/CL_0002591` + +#### Added +- [smooth muscle cell of the pulmonary artery](http://purl.obolibrary.org/obo/CL_0002591) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### smooth muscle cell of trachea `http://purl.obolibrary.org/obo/CL_0002600` + +#### Added +- [smooth muscle cell of trachea](http://purl.obolibrary.org/obo/CL_0002600) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### smooth muscle fiber of ileum `http://purl.obolibrary.org/obo/CL_1000278` + +#### Added +- [smooth muscle fiber of ileum](http://purl.obolibrary.org/obo/CL_1000278) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### smooth muscle layer in fatty layer of subcutaneous tissue `http://purl.obolibrary.org/obo/UBERON_0015783` +#### Removed +- [smooth muscle layer in fatty layer of subcutaneous tissue](http://purl.obolibrary.org/obo/UBERON_0015783) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "stratum musculosum panniculi adiposi telae subcutaneae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:77862" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [smooth muscle layer in fatty layer of subcutaneous tissue](http://purl.obolibrary.org/obo/UBERON_0015783) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "stratum musculosum panniculi adiposi telae subcutaneae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:77862" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### smooth muscle myoblast `http://purl.obolibrary.org/obo/CL_0000514` + +#### Added +- [smooth muscle myoblast](http://purl.obolibrary.org/obo/CL_0000514) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### smooth muscle tissue `http://purl.obolibrary.org/obo/UBERON_0001135` +#### Removed +- [smooth muscle tissue](http://purl.obolibrary.org/obo/UBERON_0001135) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "textus muscularis levis; textus muscularis nonstriatus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Smooth_muscle_tissue" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [smooth muscle tissue](http://purl.obolibrary.org/obo/UBERON_0001135) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "textus muscularis nonstriatus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:14070" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [smooth muscle tissue](http://purl.obolibrary.org/obo/UBERON_0001135) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "textus muscularis levis; textus muscularis nonstriatus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Smooth_muscle_tissue" + +- [smooth muscle tissue](http://purl.obolibrary.org/obo/UBERON_0001135) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "textus muscularis nonstriatus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:14070" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### sncg GABAergic cortical interneuron `http://purl.obolibrary.org/obo/CL_4023015` + +#### Added +- [sncg GABAergic cortical interneuron](http://purl.obolibrary.org/obo/CL_4023015) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### somite `http://purl.obolibrary.org/obo/UBERON_0002329` +#### Removed +- [somite](http://purl.obolibrary.org/obo/UBERON_0002329) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "somitus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Somite" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [somite](http://purl.obolibrary.org/obo/UBERON_0002329) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "somitus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Somite" + + +### sperm `http://purl.obolibrary.org/obo/CL_0000019` + +#### Added +- [sperm](http://purl.obolibrary.org/obo/CL_0000019) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### spermatic cord `http://purl.obolibrary.org/obo/UBERON_0005352` +#### Removed +- [spermatic cord](http://purl.obolibrary.org/obo/UBERON_0005352) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "funiculus spermaticus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Spermatic_cord" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [spermatic cord](http://purl.obolibrary.org/obo/UBERON_0005352) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "funiculus spermaticus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Spermatic_cord" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### sphenofrontal suture `http://purl.obolibrary.org/obo/UBERON_0010156` +#### Removed +- [sphenofrontal suture](http://purl.obolibrary.org/obo/UBERON_0010156) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "sutura sphenofrontalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Sphenofrontal_suture" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [sphenofrontal suture](http://purl.obolibrary.org/obo/UBERON_0010156) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "sutura sphenofrontalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Sphenofrontal_suture" + + +### sphenoid bone `http://purl.obolibrary.org/obo/UBERON_0001677` +#### Removed +- [sphenoid bone](http://purl.obolibrary.org/obo/UBERON_0001677) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "os sphenoidale" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:52736" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [sphenoid bone](http://purl.obolibrary.org/obo/UBERON_0001677) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "os sphenoidale" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Sphenoid_bone" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [sphenoid bone](http://purl.obolibrary.org/obo/UBERON_0001677) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "os sphenoidale" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Sphenoid_bone" + +- [sphenoid bone](http://purl.obolibrary.org/obo/UBERON_0001677) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "os sphenoidale" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:52736" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### sphincter of hepatopancreatic ampulla `http://purl.obolibrary.org/obo/UBERON_0004915` +#### Removed +- [sphincter of hepatopancreatic ampulla](http://purl.obolibrary.org/obo/UBERON_0004915) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "musculus sphincter ampullae hepatopancreatica" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:15077" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [sphincter of hepatopancreatic ampulla](http://purl.obolibrary.org/obo/UBERON_0004915) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "musculus sphincter ampullae hepatopancreatica" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:15077" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### sphincter pupillae `http://purl.obolibrary.org/obo/UBERON_0001607` +#### Removed +- [sphincter pupillae](http://purl.obolibrary.org/obo/UBERON_0001607) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "m. sphincter pupillae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Iris_sphincter_muscle" + +#### Added +- [sphincter pupillae](http://purl.obolibrary.org/obo/UBERON_0001607) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "m. sphincter pupillae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Iris_sphincter_muscle" + + +### spinal cord `http://purl.obolibrary.org/obo/UBERON_0002240` +#### Removed +- [spinal cord](http://purl.obolibrary.org/obo/UBERON_0002240) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "fissura cerebro-cerebellaris" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:22" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [spinal cord](http://purl.obolibrary.org/obo/UBERON_0002240) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "fissura cerebrocerebellaris" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:22" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [spinal cord](http://purl.obolibrary.org/obo/UBERON_0002240) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "medulla spinalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Spinal_cord" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0001279" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [spinal cord](http://purl.obolibrary.org/obo/UBERON_0002240) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "fissura cerebrocerebellaris" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:22" + +- [spinal cord](http://purl.obolibrary.org/obo/UBERON_0002240) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "medulla spinalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Spinal_cord" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0001279" + +- [spinal cord](http://purl.obolibrary.org/obo/UBERON_0002240) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "fissura cerebro-cerebellaris" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:22" + + +### spinal nerve `http://purl.obolibrary.org/obo/UBERON_0001780` +#### Removed +- [spinal nerve](http://purl.obolibrary.org/obo/UBERON_0001780) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nervi spinales" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Spinal_nerve" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [spinal nerve](http://purl.obolibrary.org/obo/UBERON_0001780) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nervi spinales" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Spinal_nerve" + + +### spinal nerve plexus `http://purl.obolibrary.org/obo/UBERON_0001813` +#### Removed +- [spinal nerve plexus](http://purl.obolibrary.org/obo/UBERON_0001813) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "plexus nervorum spinalium" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:5903" + +#### Added +- [spinal nerve plexus](http://purl.obolibrary.org/obo/UBERON_0001813) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "plexus nervorum spinalium" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:5903" + + +### spinal vein `http://purl.obolibrary.org/obo/UBERON_0006686` +#### Removed +- [spinal vein](http://purl.obolibrary.org/obo/UBERON_0006686) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "vena spinalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:76735" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [spinal vein](http://purl.obolibrary.org/obo/UBERON_0006686) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "vena spinalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:76735" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### spiral ligament `http://purl.obolibrary.org/obo/UBERON_0006725` +#### Removed +- [spiral ligament](http://purl.obolibrary.org/obo/UBERON_0006725) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ligamentum spirale ductus cochlearis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Spiral_ligament" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [spiral ligament](http://purl.obolibrary.org/obo/UBERON_0006725) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "spiral cochlear ligament" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [spiral ligament](http://purl.obolibrary.org/obo/UBERON_0006725) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ligamentum spirale ductus cochlearis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Spiral_ligament" + +- [spiral ligament](http://purl.obolibrary.org/obo/UBERON_0006725) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "spiral cochlear ligament" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### spiral organ of cochlea `http://purl.obolibrary.org/obo/UBERON_0002227` +#### Removed +- [spiral organ of cochlea](http://purl.obolibrary.org/obo/UBERON_0002227) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "organum spirale" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Organ_of_Corti" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [spiral organ of cochlea](http://purl.obolibrary.org/obo/UBERON_0002227) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "organum spirale" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Organ_of_Corti" + + +### spleen `http://purl.obolibrary.org/obo/UBERON_0002106` +#### Removed +- [spleen](http://purl.obolibrary.org/obo/UBERON_0002106) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "lien" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Spleen" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [spleen](http://purl.obolibrary.org/obo/UBERON_0002106) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "lien" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Spleen" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### spleen capsule `http://purl.obolibrary.org/obo/UBERON_0004641` +#### Removed +- [spleen capsule](http://purl.obolibrary.org/obo/UBERON_0004641) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "capsula splenica" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:15849" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [spleen capsule](http://purl.obolibrary.org/obo/UBERON_0004641) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica fibrosa splenica" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:15849" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [spleen capsule](http://purl.obolibrary.org/obo/UBERON_0004641) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica fibrosa splenica" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:15849" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [spleen capsule](http://purl.obolibrary.org/obo/UBERON_0004641) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "capsula splenica" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:15849" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### spleen venous sinus `http://purl.obolibrary.org/obo/UBERON_0009967` +#### Removed +- [spleen venous sinus](http://purl.obolibrary.org/obo/UBERON_0009967) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sinus lienalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [spleen venous sinus](http://purl.obolibrary.org/obo/UBERON_0009967) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sinus splenicus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [spleen venous sinus](http://purl.obolibrary.org/obo/UBERON_0009967) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sinus lienalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [spleen venous sinus](http://purl.obolibrary.org/obo/UBERON_0009967) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "sinus splenicus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### splenic artery `http://purl.obolibrary.org/obo/UBERON_0001194` +#### Removed +- [splenic artery](http://purl.obolibrary.org/obo/UBERON_0001194) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria lienalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Splenic_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [splenic artery](http://purl.obolibrary.org/obo/UBERON_0001194) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "arteria splenica" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Splenic_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [splenic artery](http://purl.obolibrary.org/obo/UBERON_0001194) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria lienalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Splenic_artery" + +- [splenic artery](http://purl.obolibrary.org/obo/UBERON_0001194) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "arteria splenica" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Splenic_artery" + + +### splenic vein `http://purl.obolibrary.org/obo/UBERON_0003713` +#### Removed +- [splenic vein](http://purl.obolibrary.org/obo/UBERON_0003713) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vena lienalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Splenic_vein" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [splenic vein](http://purl.obolibrary.org/obo/UBERON_0003713) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "vena splenica" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:14331" + +#### Added +- [splenic vein](http://purl.obolibrary.org/obo/UBERON_0003713) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vena lienalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Splenic_vein" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [splenic vein](http://purl.obolibrary.org/obo/UBERON_0003713) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "vena splenica" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:14331" + + +### squamous epithelial cell `http://purl.obolibrary.org/obo/CL_0000076` + +#### Added +- [squamous epithelial cell](http://purl.obolibrary.org/obo/CL_0000076) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### sst GABAergic cortical interneuron `http://purl.obolibrary.org/obo/CL_4023017` + +#### Added +- [sst GABAergic cortical interneuron](http://purl.obolibrary.org/obo/CL_4023017) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### sst chodl GABAergic cortical interneuron `http://purl.obolibrary.org/obo/CL_4023121` + +#### Added +- [sst chodl GABAergic cortical interneuron](http://purl.obolibrary.org/obo/CL_4023121) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### starburst amacrine cell `http://purl.obolibrary.org/obo/CL_0004232` + +#### Added +- [starburst amacrine cell](http://purl.obolibrary.org/obo/CL_0004232) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### stellate neuron `http://purl.obolibrary.org/obo/CL_0000122` + +#### Added +- [stellate neuron](http://purl.obolibrary.org/obo/CL_0000122) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### stem cell `http://purl.obolibrary.org/obo/CL_0000034` + +#### Added +- [stem cell](http://purl.obolibrary.org/obo/CL_0000034) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### stem cell of epidermis `http://purl.obolibrary.org/obo/CL_1000428` + +#### Added +- [stem cell of epidermis](http://purl.obolibrary.org/obo/CL_1000428) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### sternoclavicular joint `http://purl.obolibrary.org/obo/UBERON_0001469` +#### Removed +- [sternoclavicular joint](http://purl.obolibrary.org/obo/UBERON_0001469) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "articulatio sternoclavicularis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Sternoclavicular_articulation" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [sternoclavicular joint](http://purl.obolibrary.org/obo/UBERON_0001469) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "articulatio sternoclavicularis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Sternoclavicular_articulation" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### stomach `http://purl.obolibrary.org/obo/UBERON_0000945` +#### Removed +- [stomach](http://purl.obolibrary.org/obo/UBERON_0000945) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ventriculus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Stomach" + +#### Added +- [stomach](http://purl.obolibrary.org/obo/UBERON_0000945) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ventriculus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Stomach" + + +### stomodeum `http://purl.obolibrary.org/obo/UBERON_0000930` +#### Removed +- [stomodeum](http://purl.obolibrary.org/obo/UBERON_0000930) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00000439" + +#### Added +- [stomodeum](http://purl.obolibrary.org/obo/UBERON_0000930) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00000439" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### stratified epithelial cell `http://purl.obolibrary.org/obo/CL_0000079` + +#### Added +- [stratified epithelial cell](http://purl.obolibrary.org/obo/CL_0000079) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### stratum basale of epidermis `http://purl.obolibrary.org/obo/UBERON_0002025` +#### Removed +- [stratum basale of epidermis](http://purl.obolibrary.org/obo/UBERON_0002025) [has_broad_synonym](http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym) "stratum Malpighi" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Malpighian_layer" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [stratum basale of epidermis](http://purl.obolibrary.org/obo/UBERON_0002025) [has_broad_synonym](http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym) "stratum Malpighi" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Malpighian_layer" + + +### stratum corneum of epidermis `http://purl.obolibrary.org/obo/UBERON_0002027` +#### Removed +- [stratum corneum of epidermis](http://purl.obolibrary.org/obo/UBERON_0002027) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "stratum corneum epidermidis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Stratum_corneum" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [stratum corneum of epidermis](http://purl.obolibrary.org/obo/UBERON_0002027) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "stratum corneum epidermidis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Stratum_corneum" + + +### stratum spinosum of epidermis `http://purl.obolibrary.org/obo/UBERON_0002026` +#### Removed +- [stratum spinosum of epidermis](http://purl.obolibrary.org/obo/UBERON_0002026) [has_broad_synonym](http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym) "stratum Malpighii" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Malpighian" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [stratum spinosum of epidermis](http://purl.obolibrary.org/obo/UBERON_0002026) [has_broad_synonym](http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym) "stratum Malpighii" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Malpighian" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### stria vascularis of cochlear duct `http://purl.obolibrary.org/obo/UBERON_0002282` +#### Removed +- [stria vascularis of cochlear duct](http://purl.obolibrary.org/obo/UBERON_0002282) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "stria vascularis ductus cochlearis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0001819" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [stria vascularis of cochlear duct](http://purl.obolibrary.org/obo/UBERON_0002282) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "stria vascularis ductus cochlearis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0001819" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### striatum `http://purl.obolibrary.org/obo/UBERON_0002435` +#### Removed +- [striatum](http://purl.obolibrary.org/obo/UBERON_0002435) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "corpus striatum (Zilles)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:225" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [striatum](http://purl.obolibrary.org/obo/UBERON_0002435) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "corpus striatum (Zilles)" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:225" + + +### stromal cell `http://purl.obolibrary.org/obo/CL_0000499` + +#### Added +- [stromal cell](http://purl.obolibrary.org/obo/CL_0000499) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### stromal cell of lamina propria of small intestine `http://purl.obolibrary.org/obo/CL_0009022` + +#### Added +- [stromal cell of lamina propria of small intestine](http://purl.obolibrary.org/obo/CL_0009022) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### stromal cell of ovary `http://purl.obolibrary.org/obo/CL_0002132` + +#### Added +- [stromal cell of ovary](http://purl.obolibrary.org/obo/CL_0002132) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### subarachnoid space `http://purl.obolibrary.org/obo/UBERON_0000315` +#### Removed +- [subarachnoid space](http://purl.obolibrary.org/obo/UBERON_0000315) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "spatium leptomeningeum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0000230" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [subarachnoid space](http://purl.obolibrary.org/obo/UBERON_0000315) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "spatium subarachnoideum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Subarachnoid_space" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0000230" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [subarachnoid space](http://purl.obolibrary.org/obo/UBERON_0000315) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cavitas subarachnoidea" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0000230" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [subarachnoid space](http://purl.obolibrary.org/obo/UBERON_0000315) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cavum subarachnoideale" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Subarachnoid_space" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [subarachnoid space](http://purl.obolibrary.org/obo/UBERON_0000315) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cavum subarachnoideale" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Subarachnoid_space" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [subarachnoid space](http://purl.obolibrary.org/obo/UBERON_0000315) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "spatium subarachnoideum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Subarachnoid_space" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0000230" + +- [subarachnoid space](http://purl.obolibrary.org/obo/UBERON_0000315) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cavitas subarachnoidea" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0000230" + +- [subarachnoid space](http://purl.obolibrary.org/obo/UBERON_0000315) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "spatium leptomeningeum" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0000230" + + +### subclavian artery `http://purl.obolibrary.org/obo/UBERON_0001533` +#### Removed +- [subclavian artery](http://purl.obolibrary.org/obo/UBERON_0001533) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria subclavia" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Subclavian_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [subclavian artery](http://purl.obolibrary.org/obo/UBERON_0001533) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "arteria subclavia" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "XAO:0000365" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [subclavian artery](http://purl.obolibrary.org/obo/UBERON_0001533) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "arteria subclavia" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "XAO:0000365" + +- [subclavian artery](http://purl.obolibrary.org/obo/UBERON_0001533) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria subclavia" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Subclavian_artery" + + +### subclavian vein `http://purl.obolibrary.org/obo/UBERON_0001587` +#### Removed +- [subclavian vein](http://purl.obolibrary.org/obo/UBERON_0001587) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "vena subclavia" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Subclavian_vein" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [subclavian vein](http://purl.obolibrary.org/obo/UBERON_0001587) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "vena subclavia" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Subclavian_vein" + + +### subcommissural organ `http://purl.obolibrary.org/obo/UBERON_0002139` +#### Removed +- [subcommissural organ](http://purl.obolibrary.org/obo/UBERON_0002139) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "organum subcommissurale" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Subcommissural_organ" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [subcommissural organ](http://purl.obolibrary.org/obo/UBERON_0002139) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "corpus subcommissurale" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:483" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [subcommissural organ](http://purl.obolibrary.org/obo/UBERON_0002139) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "organum subcommissurale" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Subcommissural_organ" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [subcommissural organ](http://purl.obolibrary.org/obo/UBERON_0002139) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "corpus subcommissurale" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:483" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### subcutaneous adipocyte `http://purl.obolibrary.org/obo/CL_0002521` + +#### Added +- [subcutaneous adipocyte](http://purl.obolibrary.org/obo/CL_0002521) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### subcutaneous adipose tissue `http://purl.obolibrary.org/obo/UBERON_0002190` +#### Removed +- [subcutaneous adipose tissue](http://purl.obolibrary.org/obo/UBERON_0002190) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "panniculus adiposus (tela subcutanea)" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:74315" + +- [subcutaneous adipose tissue](http://purl.obolibrary.org/obo/UBERON_0002190) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "panniculus adiposus telae subcutaneae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:74315" + +#### Added +- [subcutaneous adipose tissue](http://purl.obolibrary.org/obo/UBERON_0002190) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "panniculus adiposus (tela subcutanea)" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:74315" + +- [subcutaneous adipose tissue](http://purl.obolibrary.org/obo/UBERON_0002190) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "panniculus adiposus telae subcutaneae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:74315" + +- [subcutaneous adipose tissue](http://purl.obolibrary.org/obo/UBERON_0002190) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D015434" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [LexicalMatching](https://w3id.org/semapv/vocab/LexicalMatching) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### subdivision of digestive tract `http://purl.obolibrary.org/obo/UBERON_0004921` +#### Removed +- [subdivision of digestive tract](http://purl.obolibrary.org/obo/UBERON_0004921) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00100315" + +#### Added +- [subdivision of digestive tract](http://purl.obolibrary.org/obo/UBERON_0004921) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00100315" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### subdivision of organism along appendicular axis `http://purl.obolibrary.org/obo/UBERON_0010758` +#### Removed +- [subdivision of organism along appendicular axis](http://purl.obolibrary.org/obo/UBERON_0010758) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007018" + +#### Added +- [subdivision of organism along appendicular axis](http://purl.obolibrary.org/obo/UBERON_0010758) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007018" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### subiculum `http://purl.obolibrary.org/obo/UBERON_0002191` + +#### Added +- [subiculum](http://purl.obolibrary.org/obo/UBERON_0002191) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Subiculum" + +- [subiculum](http://purl.obolibrary.org/obo/UBERON_0002191) [RO_0002171](http://purl.obolibrary.org/obo/RO_0002171) [UBERON_0004683](http://purl.obolibrary.org/obo/UBERON_0004683) + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ABA" + +- [subiculum](http://purl.obolibrary.org/obo/UBERON_0002191) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "DMBA:16163" + +- [subiculum](http://purl.obolibrary.org/obo/UBERON_0002191) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PBA:128012354" + +- [subiculum](http://purl.obolibrary.org/obo/UBERON_0002191) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BAMS:S" + +- [subiculum](http://purl.obolibrary.org/obo/UBERON_0002191) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UMLS:C0152316" + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ncithesaurus:Subiculum" + +- [subiculum](http://purl.obolibrary.org/obo/UBERON_0002191) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PBA:10054" + +- [subiculum](http://purl.obolibrary.org/obo/UBERON_0002191) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "SCTID:369097009" + +- [subiculum](http://purl.obolibrary.org/obo/UBERON_0002191) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BM:Tel-Cx-SB" + +- [subiculum](http://purl.obolibrary.org/obo/UBERON_0002191) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "subiculum cornu ammonis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0003087" + +- [subiculum](http://purl.obolibrary.org/obo/UBERON_0002191) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BIRNLEX:1305" + +- [subiculum](http://purl.obolibrary.org/obo/UBERON_0002191) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "EMAPA:35832" + +- [subiculum](http://purl.obolibrary.org/obo/UBERON_0002191) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "HBA:12896" + +- [subiculum](http://purl.obolibrary.org/obo/UBERON_0002191) [RO_0002171](http://purl.obolibrary.org/obo/RO_0002171) [UBERON_0002728](http://purl.obolibrary.org/obo/UBERON_0002728) + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ABA" + +- [subiculum](http://purl.obolibrary.org/obo/UBERON_0002191) [RO_0002171](http://purl.obolibrary.org/obo/RO_0002171) [UBERON_0001953](http://purl.obolibrary.org/obo/UBERON_0001953) + - [source](http://www.geneontology.org/formats/oboInOwl#source) "ABA" + +- [subiculum](http://purl.obolibrary.org/obo/UBERON_0002191) [UBPROP_0000009](http://purl.obolibrary.org/obo/UBPROP_0000009) "The pyramidal neurons in the subiculum exhibit transitions between two modes of action potential output: bursting and single spiking. The transitions between these two modes is thought to be important for routing information out of the hippocampus. It is the site responsible for ictal activity in some cases of human epilepsy. It has also been implicated in working memory and drug addiction.[Wikipedia:Subiculum]" + +- [subiculum](http://purl.obolibrary.org/obo/UBERON_0002191) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MA:0000960" + +- [subiculum](http://purl.obolibrary.org/obo/UBERON_0002191) [label](http://www.w3.org/2000/01/rdf-schema#label) "subiculum" + +- [subiculum](http://purl.obolibrary.org/obo/UBERON_0002191) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [pheno_slim](http://purl.obolibrary.org/obo/uberon/core#pheno_slim) + +- [subiculum](http://purl.obolibrary.org/obo/UBERON_0002191) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "gyrus parahippocampalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0003087" + +- [subiculum](http://purl.obolibrary.org/obo/UBERON_0002191) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "DHBA:10301" + +- [subiculum](http://purl.obolibrary.org/obo/UBERON_0002191) [depiction](http://xmlns.com/foaf/0.1/depiction) "https://upload.wikimedia.org/wikipedia/commons/9/99/Hippocampus.gif"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + +- [subiculum](http://purl.obolibrary.org/obo/UBERON_0002191) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0003087" + +- [subiculum](http://purl.obolibrary.org/obo/UBERON_0002191) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MBA:502" + +- [subiculum](http://purl.obolibrary.org/obo/UBERON_0002191) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "subiculum hippocampi" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:74414" + +- [subiculum](http://purl.obolibrary.org/obo/UBERON_0002191) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "neuronames:188" + +- [subiculum](http://purl.obolibrary.org/obo/UBERON_0002191) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Part of the hippocampal formation that is bounded by the entorhinal cortex and area CA1. It is characterized on the CA1 border by an abrupt widening of the pyramidal cell layer. A molecular layer is present that is continuous with that of CA1, although the stratum radiatum is no longer present. The stratum oriens is also not present. adapted from Paxinos, G. The rat central nervous system, 2nd ed, Academic Press, San Diego, 1995, pg. 468)." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BIRNLEX:1305" + +- [subiculum](http://purl.obolibrary.org/obo/UBERON_0002191) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "DHBA:10302" + +- [subiculum](http://purl.obolibrary.org/obo/UBERON_0002191) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [uberon_slim](http://purl.obolibrary.org/obo/uberon/core#uberon_slim) + +- [subiculum](http://purl.obolibrary.org/obo/UBERON_0002191) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NCIT:C33648" + +- [subiculum](http://purl.obolibrary.org/obo/UBERON_0002191) [id](http://www.geneontology.org/formats/oboInOwl#id) "UBERON:0002191" + +- [subiculum](http://purl.obolibrary.org/obo/UBERON_0002191) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:74414" + +- [subiculum](http://purl.obolibrary.org/obo/UBERON_0002191) [UBPROP_0000012](http://purl.obolibrary.org/obo/UBPROP_0000012) "In ABA SUB is part of the retrohippocampal region, along with the entorhinal area. this is in the hippocampal formation but not the hippocampal region" + - [external_ontology](http://www.geneontology.org/formats/oboInOwl#external_ontology) "ABA" + +- [subiculum](http://purl.obolibrary.org/obo/UBERON_0002191) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "subicular cortex" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BIRNLEX:1305" + +- [subiculum](http://purl.obolibrary.org/obo/UBERON_0002191) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BAMS:SUB" + +- [subiculum](http://purl.obolibrary.org/obo/UBERON_0002191) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "uberon" + +- [subiculum](http://purl.obolibrary.org/obo/UBERON_0002191) [UBPROP_0000012](http://purl.obolibrary.org/obo/UBPROP_0000012) "in DHBA subicular cortex is divided into subiculum, prosubiculum and supracallosal subiculum" + +- [subiculum](http://purl.obolibrary.org/obo/UBERON_0002191) [UBPROP_0000007](http://purl.obolibrary.org/obo/UBPROP_0000007) "subicular" + +- Class: [subiculum](http://purl.obolibrary.org/obo/UBERON_0002191) + +- [subiculum](http://purl.obolibrary.org/obo/UBERON_0002191) SubClassOf [regional part of brain](http://purl.obolibrary.org/obo/UBERON_0002616) + +- [subiculum](http://purl.obolibrary.org/obo/UBERON_0002191) SubClassOf [capable of part of](http://purl.obolibrary.org/obo/RO_0002216) some [memory](http://purl.obolibrary.org/obo/GO_0007613) + - [source](http://www.geneontology.org/formats/oboInOwl#source) "Wikipedia" + +- [subiculum](http://purl.obolibrary.org/obo/UBERON_0002191) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [hippocampal formation](http://purl.obolibrary.org/obo/UBERON_0002421) + - [source](http://www.geneontology.org/formats/oboInOwl#source) "NIFSTD" + + +### submucosa of bronchus `http://purl.obolibrary.org/obo/UBERON_0001957` +#### Removed +- [submucosa of bronchus](http://purl.obolibrary.org/obo/UBERON_0001957) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tela submucosa bronchi" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:62653" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [submucosa of bronchus](http://purl.obolibrary.org/obo/UBERON_0001957) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tela submucosa bronchi" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:62653" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### submucosa of esophagus `http://purl.obolibrary.org/obo/UBERON_0001972` +#### Removed +- [submucosa of esophagus](http://purl.obolibrary.org/obo/UBERON_0001972) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tela submucosa (oesophagus)" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:62997" + +- [submucosa of esophagus](http://purl.obolibrary.org/obo/UBERON_0001972) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tela submucosa oesophageae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:62997" + +- [submucosa of esophagus](http://purl.obolibrary.org/obo/UBERON_0001972) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tela submucosa esophagi" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0002109" + +#### Added +- [submucosa of esophagus](http://purl.obolibrary.org/obo/UBERON_0001972) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tela submucosa esophagi" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0002109" + +- [submucosa of esophagus](http://purl.obolibrary.org/obo/UBERON_0001972) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tela submucosa oesophageae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:62997" + +- [submucosa of esophagus](http://purl.obolibrary.org/obo/UBERON_0001972) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tela submucosa (oesophagus)" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:62997" + + +### submucosa of large intestine `http://purl.obolibrary.org/obo/UBERON_0001208` +#### Removed +- [submucosa of large intestine](http://purl.obolibrary.org/obo/UBERON_0001208) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tela submucosa intestini crassi" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:14970" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [submucosa of large intestine](http://purl.obolibrary.org/obo/UBERON_0001208) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tela submucosa intestini crassi" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:14970" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### submucosa of pharynx `http://purl.obolibrary.org/obo/UBERON_0004924` +#### Removed +- [submucosa of pharynx](http://purl.obolibrary.org/obo/UBERON_0004924) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tela submucosa pharyngea" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:75144" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [submucosa of pharynx](http://purl.obolibrary.org/obo/UBERON_0004924) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tela submucosa pharyngis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0002113" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [submucosa of pharynx](http://purl.obolibrary.org/obo/UBERON_0004924) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tela submucosa pharyngea" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:75144" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [submucosa of pharynx](http://purl.obolibrary.org/obo/UBERON_0004924) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tela submucosa pharyngis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0002113" + + +### submucosa of rectum `http://purl.obolibrary.org/obo/UBERON_0003330` +#### Removed +- [submucosa of rectum](http://purl.obolibrary.org/obo/UBERON_0003330) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tela submucosa recti" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0002114" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [submucosa of rectum](http://purl.obolibrary.org/obo/UBERON_0003330) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tela submucosa recti" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0002114" + + +### submucosa of small intestine `http://purl.obolibrary.org/obo/UBERON_0001205` +#### Removed +- [submucosa of small intestine](http://purl.obolibrary.org/obo/UBERON_0001205) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tela submucosa intestini tenuis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0002112" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [submucosa of small intestine](http://purl.obolibrary.org/obo/UBERON_0001205) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tela submucosa intestini tenuis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0002112" + + +### submucosa of stomach `http://purl.obolibrary.org/obo/UBERON_0001200` +#### Removed +- [submucosa of stomach](http://purl.obolibrary.org/obo/UBERON_0001200) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tela submucosa gastricae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:14908" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [submucosa of stomach](http://purl.obolibrary.org/obo/UBERON_0001200) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tela submucosa gastricae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:14908" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### submucosa of urinary bladder `http://purl.obolibrary.org/obo/UBERON_0004943` +#### Removed +- [submucosa of urinary bladder](http://purl.obolibrary.org/obo/UBERON_0004943) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tela submucosa vesicae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:15929" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [submucosa of urinary bladder](http://purl.obolibrary.org/obo/UBERON_0004943) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tela submucosa (vesica urinaria)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:15929" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [submucosa of urinary bladder](http://purl.obolibrary.org/obo/UBERON_0004943) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tela submucosa vesicae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:15929" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [submucosa of urinary bladder](http://purl.obolibrary.org/obo/UBERON_0004943) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tela submucosa (vesica urinaria)" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:15929" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### submucosa of uterine tube `http://purl.obolibrary.org/obo/UBERON_0011298` +#### Removed +- [submucosa of uterine tube](http://purl.obolibrary.org/obo/UBERON_0011298) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tela submucosa tubae uterinae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0002116" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [submucosa of uterine tube](http://purl.obolibrary.org/obo/UBERON_0011298) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tela submucosa tubae uterinae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0002116" + + +### subscapular artery `http://purl.obolibrary.org/obo/UBERON_0001397` +#### Removed +- [subscapular artery](http://purl.obolibrary.org/obo/UBERON_0001397) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria subscapularis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Subscapular_artery" + +#### Added +- [subscapular artery](http://purl.obolibrary.org/obo/UBERON_0001397) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria subscapularis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Subscapular_artery" + + +### substantia nigra `http://purl.obolibrary.org/obo/UBERON_0002038` +#### Removed +- [substantia nigra](http://purl.obolibrary.org/obo/UBERON_0002038) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "substantia nigra (Soemmerringi)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:536" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [substantia nigra](http://purl.obolibrary.org/obo/UBERON_0002038) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus pigmentosus subthalamo-peduncularis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:536" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [substantia nigra](http://purl.obolibrary.org/obo/UBERON_0002038) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "substantia nigra (Soemmerringi)" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:536" + +- [substantia nigra](http://purl.obolibrary.org/obo/UBERON_0002038) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus pigmentosus subthalamo-peduncularis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:536" + + +### substantia propria of cornea `http://purl.obolibrary.org/obo/UBERON_0001777` +#### Removed +- [substantia propria of cornea](http://purl.obolibrary.org/obo/UBERON_0001777) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "substantia propria corneae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:58306" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [substantia propria of cornea](http://purl.obolibrary.org/obo/UBERON_0001777) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "substantia propria corneae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:58306" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### substantia propria of sclera `http://purl.obolibrary.org/obo/UBERON_0010295` +#### Removed +- [substantia propria of sclera](http://purl.obolibrary.org/obo/UBERON_0010295) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "substantia propria sclerae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:58365" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [substantia propria of sclera](http://purl.obolibrary.org/obo/UBERON_0010295) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "substantia propria sclerae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:58365" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### substratum of layer of retina `http://purl.obolibrary.org/obo/UBERON_0008921` +#### Removed +- [substratum of layer of retina](http://purl.obolibrary.org/obo/UBERON_0008921) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "http://retina.anatomy.upenn.edu/~lance/eye/retina_gross.html" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UBERON:CL_meeting_20110725" + +#### Added +- [substratum of layer of retina](http://purl.obolibrary.org/obo/UBERON_0008921) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Missing definition for term UBERON:0008921. Please replace it using linked reference." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UBERON:CL_meeting_20110725" + + +### superior mesenteric artery `http://purl.obolibrary.org/obo/UBERON_0001182` +#### Removed +- [superior mesenteric artery](http://purl.obolibrary.org/obo/UBERON_0001182) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria mesenterica superior" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Superior_mesenteric_artery" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0002303" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [superior mesenteric artery](http://purl.obolibrary.org/obo/UBERON_0001182) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria mesenterica superior" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Superior_mesenteric_artery" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0002303" + + +### superior mesenteric vein `http://purl.obolibrary.org/obo/UBERON_0001138` +#### Removed +- [superior mesenteric vein](http://purl.obolibrary.org/obo/UBERON_0001138) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vena mesenterica superior" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Superior_mesenteric_vein" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [superior mesenteric vein](http://purl.obolibrary.org/obo/UBERON_0001138) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vena mesenterica superior" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Superior_mesenteric_vein" + + +### superior olivary complex `http://purl.obolibrary.org/obo/UBERON_0002128` +#### Removed +- [superior olivary complex](http://purl.obolibrary.org/obo/UBERON_0002128) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D065832" + +- [superior olivary complex](http://purl.obolibrary.org/obo/UBERON_0002128) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "regio olivaris superioris" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:569" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [superior olivary complex](http://purl.obolibrary.org/obo/UBERON_0002128) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nucleus olivaris superior" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:72247" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [superior olivary complex](http://purl.obolibrary.org/obo/UBERON_0002128) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nucleus olivaris superior" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:72247" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [superior olivary complex](http://purl.obolibrary.org/obo/UBERON_0002128) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "regio olivaris superioris" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:569" + +- [superior olivary complex](http://purl.obolibrary.org/obo/UBERON_0002128) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D065832" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [author_id](https://w3id.org/sssom/author_id) [0000-0001-9439-5346](https://orcid.org/0000-0001-9439-5346) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### superior salivatory nucleus `http://purl.obolibrary.org/obo/UBERON_0002149` +#### Removed +- [superior salivatory nucleus](http://purl.obolibrary.org/obo/UBERON_0002149) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus salivatorius cranialis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:590" + +- [superior salivatory nucleus](http://purl.obolibrary.org/obo/UBERON_0002149) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus salivatorius superior" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:590" + +- [superior salivatory nucleus](http://purl.obolibrary.org/obo/UBERON_0002149) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus salivatorius rostralis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:590" + +- [superior salivatory nucleus](http://purl.obolibrary.org/obo/UBERON_0002149) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus salivarius superior" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:590" + +#### Added +- [superior salivatory nucleus](http://purl.obolibrary.org/obo/UBERON_0002149) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus salivarius superior" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:590" + +- [superior salivatory nucleus](http://purl.obolibrary.org/obo/UBERON_0002149) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus salivatorius cranialis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:590" + +- [superior salivatory nucleus](http://purl.obolibrary.org/obo/UBERON_0002149) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus salivatorius rostralis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:590" + +- [superior salivatory nucleus](http://purl.obolibrary.org/obo/UBERON_0002149) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus salivatorius superior" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:590" + + +### superior vesical artery `http://purl.obolibrary.org/obo/UBERON_0001312` +#### Removed +- [superior vesical artery](http://purl.obolibrary.org/obo/UBERON_0001312) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "arteria vesicalis superior" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Superior_vesical_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [superior vesical artery](http://purl.obolibrary.org/obo/UBERON_0001312) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "arteria vesicali superior" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Superior_vesical_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [superior vesical artery](http://purl.obolibrary.org/obo/UBERON_0001312) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteriae vesicales superiores" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Superior_vesical_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [superior vesical artery](http://purl.obolibrary.org/obo/UBERON_0001312) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteriae vesicales superiores" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Superior_vesical_artery" + +- [superior vesical artery](http://purl.obolibrary.org/obo/UBERON_0001312) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "arteria vesicali superior" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Superior_vesical_artery" + +- [superior vesical artery](http://purl.obolibrary.org/obo/UBERON_0001312) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "arteria vesicalis superior" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Superior_vesical_artery" + + +### supporting cell `http://purl.obolibrary.org/obo/CL_0000630` + +#### Added +- [supporting cell](http://purl.obolibrary.org/obo/CL_0000630) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### surface ectodermal cell `http://purl.obolibrary.org/obo/CL_0000114` + +#### Added +- [surface ectodermal cell](http://purl.obolibrary.org/obo/CL_0000114) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### sympathetic ganglion `http://purl.obolibrary.org/obo/UBERON_0001806` +#### Removed +- [sympathetic ganglion](http://purl.obolibrary.org/obo/UBERON_0001806) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D005728" + +- [sympathetic ganglion](http://purl.obolibrary.org/obo/UBERON_0001806) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ganglion sympathicum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0001333" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Sympathetic_ganglion" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [sympathetic ganglion](http://purl.obolibrary.org/obo/UBERON_0001806) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ganglion sympathicum" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0001333" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Sympathetic_ganglion" + +- [sympathetic ganglion](http://purl.obolibrary.org/obo/UBERON_0001806) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D005728" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [author_id](https://w3id.org/sssom/author_id) [0000-0001-9439-5346](https://orcid.org/0000-0001-9439-5346) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### sympathetic nervous system `http://purl.obolibrary.org/obo/UBERON_0000013` +#### Removed +- [sympathetic nervous system](http://purl.obolibrary.org/obo/UBERON_0000013) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pars sympathica divisionis autonomici systematis nervosi" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:9906" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [sympathetic nervous system](http://purl.obolibrary.org/obo/UBERON_0000013) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "pars sympathica divisionis autonomici systematis nervosi" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Sympathetic_nervous_system" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [sympathetic nervous system](http://purl.obolibrary.org/obo/UBERON_0000013) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "pars sympathica divisionis autonomici systematis nervosi" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Sympathetic_nervous_system" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [sympathetic nervous system](http://purl.obolibrary.org/obo/UBERON_0000013) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pars sympathica divisionis autonomici systematis nervosi" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:9906" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### sympathetic neuron `http://purl.obolibrary.org/obo/CL_0011103` + +#### Added +- [sympathetic neuron](http://purl.obolibrary.org/obo/CL_0011103) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### sympathetic trunk `http://purl.obolibrary.org/obo/UBERON_0000407` +#### Removed +- [sympathetic trunk](http://purl.obolibrary.org/obo/UBERON_0000407) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "truncus sympathicus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Sympathetic_trunk" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [sympathetic trunk](http://purl.obolibrary.org/obo/UBERON_0000407) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "truncus sympathicus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Sympathetic_trunk" + + +### synaptic signaling by nitric oxide `http://purl.obolibrary.org/obo/GO_0099163` +#### Removed +- [synaptic signaling by nitric oxide](http://purl.obolibrary.org/obo/GO_0099163) [label](http://www.w3.org/2000/01/rdf-schema#label) "synaptic signaling by nitric oxide" + +- [synaptic signaling by nitric oxide](http://purl.obolibrary.org/obo/GO_0099163) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Cell-cell signaling to or from a synapse, mediated by nitric oxide." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:dos" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:19038221" + +- [synaptic signaling by nitric oxide](http://purl.obolibrary.org/obo/GO_0099163) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [synaptic signaling by nitric oxide](http://purl.obolibrary.org/obo/GO_0099163) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0099163" + +- [synaptic signaling by nitric oxide](http://purl.obolibrary.org/obo/GO_0099163) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_synapse](http://purl.obolibrary.org/obo/go#goslim_synapse) + +- Class: [synaptic signaling by nitric oxide](http://purl.obolibrary.org/obo/GO_0099163) + +- [synaptic signaling by nitric oxide](http://purl.obolibrary.org/obo/GO_0099163) EquivalentTo [synaptic signaling](http://purl.obolibrary.org/obo/GO_0099536) and ([process has causal agent](http://purl.obolibrary.org/obo/RO_0002608) some [CHEBI_16480](http://purl.obolibrary.org/obo/CHEBI_16480)) + +- [synaptic signaling by nitric oxide](http://purl.obolibrary.org/obo/GO_0099163) SubClassOf [process has causal agent](http://purl.obolibrary.org/obo/RO_0002608) some [CHEBI_16480](http://purl.obolibrary.org/obo/CHEBI_16480) + +- [synaptic signaling by nitric oxide](http://purl.obolibrary.org/obo/GO_0099163) SubClassOf [synaptic signaling](http://purl.obolibrary.org/obo/GO_0099536) + + + +### synchondrosis `http://purl.obolibrary.org/obo/UBERON_0002215` +#### Removed +- [synchondrosis](http://purl.obolibrary.org/obo/UBERON_0002215) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cartilago epiphysialis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:7497" + +#### Added +- [synchondrosis](http://purl.obolibrary.org/obo/UBERON_0002215) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cartilago epiphysialis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:7497" + + +### syncytiotrophoblast `http://purl.obolibrary.org/obo/UBERON_0000371` +#### Removed +- [syncytiotrophoblast](http://purl.obolibrary.org/obo/UBERON_0000371) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "syncitiotrophoblastus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Syncytiotrophoblast" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [syncytiotrophoblast](http://purl.obolibrary.org/obo/UBERON_0000371) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "syncitiotrophoblastus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Syncytiotrophoblast" + + +### syncytiotrophoblast cell `http://purl.obolibrary.org/obo/CL_0000525` + +#### Added +- [syncytiotrophoblast cell](http://purl.obolibrary.org/obo/CL_0000525) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### synovial membrane of synovial joint `http://purl.obolibrary.org/obo/UBERON_0002018` +#### Removed +- [synovial membrane of synovial joint](http://purl.obolibrary.org/obo/UBERON_0002018) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "stratum synoviale (capsula articularis)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:9865" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [synovial membrane of synovial joint](http://purl.obolibrary.org/obo/UBERON_0002018) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "membrana synovialis capsulae articularis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Synovial_membrane" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [synovial membrane of synovial joint](http://purl.obolibrary.org/obo/UBERON_0002018) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "stratum synoviale" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:66762" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [synovial membrane of synovial joint](http://purl.obolibrary.org/obo/UBERON_0002018) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "membrana synovialis (capsula articularis)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:9865" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [synovial membrane of synovial joint](http://purl.obolibrary.org/obo/UBERON_0002018) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "membrana synovialis capsulae articularis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Synovial_membrane" + +- [synovial membrane of synovial joint](http://purl.obolibrary.org/obo/UBERON_0002018) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "membrana synovialis (capsula articularis)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:9865" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [synovial membrane of synovial joint](http://purl.obolibrary.org/obo/UBERON_0002018) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "stratum synoviale" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:66762" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [synovial membrane of synovial joint](http://purl.obolibrary.org/obo/UBERON_0002018) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "stratum synoviale (capsula articularis)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:9865" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### tanycyte `http://purl.obolibrary.org/obo/CL_0002085` + +#### Added +- [tanycyte](http://purl.obolibrary.org/obo/CL_0002085) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### tarsal region `http://purl.obolibrary.org/obo/UBERON_0004454` +#### Removed +- [tarsal region](http://purl.obolibrary.org/obo/UBERON_0004454) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "articulatio talocruralis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Ankle" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [tarsal region](http://purl.obolibrary.org/obo/UBERON_0004454) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "articulatio talocruralis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Ankle" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### tarsometatarsal joint `http://purl.obolibrary.org/obo/UBERON_0011118` +#### Removed +- [tarsometatarsal joint](http://purl.obolibrary.org/obo/UBERON_0011118) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "articulationes tarsometatarsales" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Tarsometatarsal_articulations" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [tarsometatarsal joint](http://purl.obolibrary.org/obo/UBERON_0011118) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "articulationes tarsometatarsales" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Tarsometatarsal_articulations" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### taste receptor cell `http://purl.obolibrary.org/obo/CL_0000209` + +#### Added +- [taste receptor cell](http://purl.obolibrary.org/obo/CL_0000209) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### tela choroidea of fourth ventricle `http://purl.obolibrary.org/obo/UBERON_0005287` +#### Removed +- [tela choroidea of fourth ventricle](http://purl.obolibrary.org/obo/UBERON_0005287) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tela choroidea ventriculi quarti" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Tela_chorioidea_of_fourth_ventricle" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [tela choroidea of fourth ventricle](http://purl.obolibrary.org/obo/UBERON_0005287) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tela choroidea ventriculi quarti" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:78493" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [tela choroidea of fourth ventricle](http://purl.obolibrary.org/obo/UBERON_0005287) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tela choroidea ventriculi quarti" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:78493" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [tela choroidea of fourth ventricle](http://purl.obolibrary.org/obo/UBERON_0005287) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tela choroidea ventriculi quarti" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Tela_chorioidea_of_fourth_ventricle" + + +### tela choroidea of telencephalic ventricle `http://purl.obolibrary.org/obo/UBERON_0005289` +#### Removed +- [tela choroidea of telencephalic ventricle](http://purl.obolibrary.org/obo/UBERON_0005289) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tela choroidea (ventriculi lateralis)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:83712" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [tela choroidea of telencephalic ventricle](http://purl.obolibrary.org/obo/UBERON_0005289) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tela choroidea (ventriculi lateralis)" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:83712" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### temporal bone `http://purl.obolibrary.org/obo/UBERON_0001678` +#### Removed +- [temporal bone](http://purl.obolibrary.org/obo/UBERON_0001678) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "os temporale" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Temporal_bone" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [temporal bone](http://purl.obolibrary.org/obo/UBERON_0001678) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "os temporale" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Temporal_bone" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### temporal cortex `http://purl.obolibrary.org/obo/UBERON_0016538` + +#### Added +- [temporal cortex](http://purl.obolibrary.org/obo/UBERON_0016538) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D013702" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [LexicalMatching](https://w3id.org/semapv/vocab/LexicalMatching) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### temporal lobe `http://purl.obolibrary.org/obo/UBERON_0001871` +#### Removed +- [temporal lobe](http://purl.obolibrary.org/obo/UBERON_0001871) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lobus temporalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Temporal_lobe" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [temporal lobe](http://purl.obolibrary.org/obo/UBERON_0001871) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lobus temporalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Temporal_lobe" + + +### tendon `http://purl.obolibrary.org/obo/UBERON_0000043` +#### Removed +- [tendon](http://purl.obolibrary.org/obo/UBERON_0000043) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tendo" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Tendon" + +#### Added +- [tendon](http://purl.obolibrary.org/obo/UBERON_0000043) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tendo" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Tendon" + + +### tendon cell `http://purl.obolibrary.org/obo/CL_0000388` + +#### Added +- [tendon cell](http://purl.obolibrary.org/obo/CL_0000388) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### tendon sheath `http://purl.obolibrary.org/obo/UBERON_0000304` +#### Removed +- [tendon sheath](http://purl.obolibrary.org/obo/UBERON_0000304) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vagina tendinis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Tendon_sheath" + +#### Added +- [tendon sheath](http://purl.obolibrary.org/obo/UBERON_0000304) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vagina tendinis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Tendon_sheath" + + +### terminal bronchiole `http://purl.obolibrary.org/obo/UBERON_0002187` +#### Removed +- [terminal bronchiole](http://purl.obolibrary.org/obo/UBERON_0002187) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "bronchioli terminalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Terminal_bronchiole" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [terminal bronchiole](http://purl.obolibrary.org/obo/UBERON_0002187) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "bronchiolus terminalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [terminal bronchiole](http://purl.obolibrary.org/obo/UBERON_0002187) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "bronchiolus terminalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [terminal bronchiole](http://purl.obolibrary.org/obo/UBERON_0002187) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "bronchioli terminalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Terminal_bronchiole" + + +### terminal part of digestive tract `http://purl.obolibrary.org/obo/UBERON_0006866` +#### Removed +- [terminal part of digestive tract](http://purl.obolibrary.org/obo/UBERON_0006866) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005756" + +#### Added +- [terminal part of digestive tract](http://purl.obolibrary.org/obo/UBERON_0006866) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00005756" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### tertiary ovarian follicle `http://purl.obolibrary.org/obo/UBERON_0000037` +#### Removed +- [tertiary ovarian follicle](http://purl.obolibrary.org/obo/UBERON_0000037) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "folliculi ovarici vesiculosi" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:18641" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [tertiary ovarian follicle](http://purl.obolibrary.org/obo/UBERON_0000037) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "folliculi ovarici vesiculosi" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:18641" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### testicular artery `http://purl.obolibrary.org/obo/UBERON_0001187` +#### Removed +- [testicular artery](http://purl.obolibrary.org/obo/UBERON_0001187) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria testicularis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Testicular_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [testicular artery](http://purl.obolibrary.org/obo/UBERON_0001187) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria testicularis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Testicular_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### testicular vein `http://purl.obolibrary.org/obo/UBERON_0001144` +#### Removed +- [testicular vein](http://purl.obolibrary.org/obo/UBERON_0001144) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vena testicularis sinistra" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Testicular_vein" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [testicular vein](http://purl.obolibrary.org/obo/UBERON_0001144) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vena testicularis dextra" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Testicular_vein" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [testicular vein](http://purl.obolibrary.org/obo/UBERON_0001144) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "venae spermaticae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Testicular_vein" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [testicular vein](http://purl.obolibrary.org/obo/UBERON_0001144) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vena testicularis dextra" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Testicular_vein" + +- [testicular vein](http://purl.obolibrary.org/obo/UBERON_0001144) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vena testicularis sinistra" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Testicular_vein" + +- [testicular vein](http://purl.obolibrary.org/obo/UBERON_0001144) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "venae spermaticae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Testicular_vein" + + +### testis `http://purl.obolibrary.org/obo/UBERON_0000473` +#### Removed +- [testis](http://purl.obolibrary.org/obo/UBERON_0000473) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "testiculus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0001363" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [testis](http://purl.obolibrary.org/obo/UBERON_0000473) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00004928" + +#### Added +- [testis](http://purl.obolibrary.org/obo/UBERON_0000473) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00004928" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + +- [testis](http://purl.obolibrary.org/obo/UBERON_0000473) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "testiculus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0001363" + + +### tetrapod frontal bone `http://purl.obolibrary.org/obo/UBERON_0000209` +#### Removed +- [tetrapod frontal bone](http://purl.obolibrary.org/obo/UBERON_0000209) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "os frontale" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Frontal_bone" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [tetrapod frontal bone](http://purl.obolibrary.org/obo/UBERON_0000209) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "os frontale" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Frontal_bone" + + +### theca cell `http://purl.obolibrary.org/obo/CL_0000503` + +#### Added +- [theca cell](http://purl.obolibrary.org/obo/CL_0000503) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### theca cell layer `http://purl.obolibrary.org/obo/UBERON_0000155` +#### Removed +- [theca cell layer](http://purl.obolibrary.org/obo/UBERON_0000155) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "theca folliculi" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Theca_of_follicle" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [theca cell layer](http://purl.obolibrary.org/obo/UBERON_0000155) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "theca folliculi" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Theca_of_follicle" + + +### thick ascending limb of loop of Henle `http://purl.obolibrary.org/obo/UBERON_0001291` +#### Removed +- [thick ascending limb of loop of Henle](http://purl.obolibrary.org/obo/UBERON_0001291) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tubulus rectus distalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Thick_ascending_limb_of_loop_of_Henle" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [thick ascending limb of loop of Henle](http://purl.obolibrary.org/obo/UBERON_0001291) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tubulus rectus distalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Thick_ascending_limb_of_loop_of_Henle" + + +### thoracic aorta `http://purl.obolibrary.org/obo/UBERON_0001515` +#### Removed +- [thoracic aorta](http://purl.obolibrary.org/obo/UBERON_0001515) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "aorta thoracica" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:3786" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [thoracic aorta](http://purl.obolibrary.org/obo/UBERON_0001515) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "aorta thoracalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Thoracic_aorta" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [thoracic aorta](http://purl.obolibrary.org/obo/UBERON_0001515) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "pars thoracica aortae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Thoracic_aorta" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [thoracic aorta](http://purl.obolibrary.org/obo/UBERON_0001515) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "aorta thoracica" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:3786" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [thoracic aorta](http://purl.obolibrary.org/obo/UBERON_0001515) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "aorta thoracalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Thoracic_aorta" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [thoracic aorta](http://purl.obolibrary.org/obo/UBERON_0001515) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "pars thoracica aortae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Thoracic_aorta" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### thoracic cavity `http://purl.obolibrary.org/obo/UBERON_0002224` +#### Removed +- [thoracic cavity](http://purl.obolibrary.org/obo/UBERON_0002224) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cavitas thoracis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Thoracic_cavity" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [thoracic cavity](http://purl.obolibrary.org/obo/UBERON_0002224) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cavitas thoracis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Thoracic_cavity" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### thoracic ganglion `http://purl.obolibrary.org/obo/UBERON_0000961` +#### Removed +- [thoracic ganglion](http://purl.obolibrary.org/obo/UBERON_0000961) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ganglion thoracicum splanchnicum" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:6471" + +#### Added +- [thoracic ganglion](http://purl.obolibrary.org/obo/UBERON_0000961) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ganglion thoracicum splanchnicum" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:6471" + + +### thoracic nerve `http://purl.obolibrary.org/obo/UBERON_0003726` +#### Removed +- [thoracic nerve](http://purl.obolibrary.org/obo/UBERON_0003726) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nervus thoracis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:5860" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [thoracic nerve](http://purl.obolibrary.org/obo/UBERON_0003726) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nervi thoracici" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Thoracic_nerves" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [thoracic nerve](http://purl.obolibrary.org/obo/UBERON_0003726) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nervi thoracici" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Thoracic_nerves" + +- [thoracic nerve](http://purl.obolibrary.org/obo/UBERON_0003726) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nervus thoracis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:5860" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### thoracic rib cage `http://purl.obolibrary.org/obo/UBERON_0003252` +#### Removed +- [thoracic rib cage](http://purl.obolibrary.org/obo/UBERON_0003252) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cavea thoracis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:7480" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [thoracic rib cage](http://purl.obolibrary.org/obo/UBERON_0003252) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cavea thoracis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Human_rib_cage" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [thoracic rib cage](http://purl.obolibrary.org/obo/UBERON_0003252) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cavea thoracis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:7480" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [thoracic rib cage](http://purl.obolibrary.org/obo/UBERON_0003252) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cavea thoracis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Human_rib_cage" + + +### thoracic spinal cord `http://purl.obolibrary.org/obo/UBERON_0003038` +#### Removed +- [thoracic spinal cord](http://purl.obolibrary.org/obo/UBERON_0003038) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pars thoracica medullae spinalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:71167" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [thoracic spinal cord](http://purl.obolibrary.org/obo/UBERON_0003038) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "segmenta thoracica medullae spinalis [1-12]" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:71167" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [thoracic spinal cord](http://purl.obolibrary.org/obo/UBERON_0003038) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "segmenta thoracica medullae spinalis [1-12]" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:71167" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +- [thoracic spinal cord](http://purl.obolibrary.org/obo/UBERON_0003038) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pars thoracica medullae spinalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:71167" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### thoracodorsal artery `http://purl.obolibrary.org/obo/UBERON_0002011` +#### Removed +- [thoracodorsal artery](http://purl.obolibrary.org/obo/UBERON_0002011) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria thoracodorsalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Thoracodorsal_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [thoracodorsal artery](http://purl.obolibrary.org/obo/UBERON_0002011) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteria thoracodorsalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Thoracodorsal_artery" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### thymic vein `http://purl.obolibrary.org/obo/UBERON_0001591` +#### Removed +- [thymic vein](http://purl.obolibrary.org/obo/UBERON_0001591) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "venae thymicae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Thymic_veins" + +- [thymic vein](http://purl.obolibrary.org/obo/UBERON_0001591) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "vena thymica" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Thymic_veins" + +#### Added +- [thymic vein](http://purl.obolibrary.org/obo/UBERON_0001591) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "venae thymicae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Thymic_veins" + +- [thymic vein](http://purl.obolibrary.org/obo/UBERON_0001591) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "vena thymica" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Thymic_veins" + + +### thymocyte `http://purl.obolibrary.org/obo/CL_0000893` + +#### Added +- [thymocyte](http://purl.obolibrary.org/obo/CL_0000893) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### thyroid diverticulum `http://purl.obolibrary.org/obo/UBERON_0007689` +#### Removed +- [thyroid diverticulum](http://purl.obolibrary.org/obo/UBERON_0007689) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "diverticulum thyroideum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Thyroid_diverticulum" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [thyroid diverticulum](http://purl.obolibrary.org/obo/UBERON_0007689) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "saccus thyroideus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Thyroid_diverticulum" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [thyroid diverticulum](http://purl.obolibrary.org/obo/UBERON_0007689) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "saccus thyroideus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Thyroid_diverticulum" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [thyroid diverticulum](http://purl.obolibrary.org/obo/UBERON_0007689) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "diverticulum thyroideum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Thyroid_diverticulum" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### thyroid follicular cell `http://purl.obolibrary.org/obo/CL_0002258` + +#### Added +- [thyroid follicular cell](http://purl.obolibrary.org/obo/CL_0002258) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### thyroid gland `http://purl.obolibrary.org/obo/UBERON_0002046` +#### Removed +- [thyroid gland](http://purl.obolibrary.org/obo/UBERON_0002046) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "glandula thyroidea" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Thyroid" + +#### Added +- [thyroid gland](http://purl.obolibrary.org/obo/UBERON_0002046) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "glandula thyroidea" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Thyroid" + + +### tibial nerve `http://purl.obolibrary.org/obo/UBERON_0001323` +#### Removed +- [tibial nerve](http://purl.obolibrary.org/obo/UBERON_0001323) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "n. tibialis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Tibial_nerve" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [tibial nerve](http://purl.obolibrary.org/obo/UBERON_0001323) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "n. tibialis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Tibial_nerve" + + +### tissue `http://purl.obolibrary.org/obo/UBERON_0000479` +#### Removed +- [tissue](http://purl.obolibrary.org/obo/UBERON_0000479) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007003" + +#### Added +- [tissue](http://purl.obolibrary.org/obo/UBERON_0000479) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00007003" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + +### tissue-resident macrophage `http://purl.obolibrary.org/obo/CL_0000864` + +#### Added +- [tissue-resident macrophage](http://purl.obolibrary.org/obo/CL_0000864) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### tongue muscle `http://purl.obolibrary.org/obo/UBERON_0000378` +#### Removed +- [tongue muscle](http://purl.obolibrary.org/obo/UBERON_0000378) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "musculi linguae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Muscles_of_tongue" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [tongue muscle](http://purl.obolibrary.org/obo/UBERON_0000378) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "musculi linguae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Muscles_of_tongue" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### tongue muscle cell `http://purl.obolibrary.org/obo/CL_0002673` + +#### Added +- [tongue muscle cell](http://purl.obolibrary.org/obo/CL_0002673) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### tonsil germinal center B cell `http://purl.obolibrary.org/obo/CL_2000006` + +#### Added +- [tonsil germinal center B cell](http://purl.obolibrary.org/obo/CL_2000006) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### tonsillar ring `http://purl.obolibrary.org/obo/UBERON_0001735` +#### Removed +- [tonsillar ring](http://purl.obolibrary.org/obo/UBERON_0001735) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "anulus lymphoideus pharyngis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:55070" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [tonsillar ring](http://purl.obolibrary.org/obo/UBERON_0001735) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "anulus lymphoideus pharyngis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:55070" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### tooth enamel organ `http://purl.obolibrary.org/obo/UBERON_0005176` +#### Removed +- [tooth enamel organ](http://purl.obolibrary.org/obo/UBERON_0005176) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "organum enameleum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Enamel_organ" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [tooth enamel organ](http://purl.obolibrary.org/obo/UBERON_0005176) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "organum enameleum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Enamel_organ" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + +### trabecula carnea `http://purl.obolibrary.org/obo/UBERON_0002511` +#### Removed +- [trabecula carnea](http://purl.obolibrary.org/obo/UBERON_0002511) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "columnae carneae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Trabeculae_carneae" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [trabecula carnea](http://purl.obolibrary.org/obo/UBERON_0002511) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "trabeculae carneae cordis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Trabeculae_carneae" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [trabecula carnea](http://purl.obolibrary.org/obo/UBERON_0002511) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "trabeculae carneae cordis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Trabeculae_carneae" + +- [trabecula carnea](http://purl.obolibrary.org/obo/UBERON_0002511) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "columnae carneae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Trabeculae_carneae" + + +### trachea cartilage `http://purl.obolibrary.org/obo/UBERON_0003604` +#### Removed +- [trachea cartilage](http://purl.obolibrary.org/obo/UBERON_0003604) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cartilagines tracheales" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Tracheal_rings" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [trachea cartilage](http://purl.obolibrary.org/obo/UBERON_0003604) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cartilagines tracheales" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Tracheal_rings" + + +### tracheal goblet cell `http://purl.obolibrary.org/obo/CL_1000329` + +#### Added +- [tracheal goblet cell](http://purl.obolibrary.org/obo/CL_1000329) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### tracheal mucosa `http://purl.obolibrary.org/obo/UBERON_0000379` +#### Removed +- [tracheal mucosa](http://purl.obolibrary.org/obo/UBERON_0000379) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica mucosa tracheae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:7471" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [tracheal mucosa](http://purl.obolibrary.org/obo/UBERON_0000379) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica mucosa tracheae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:7471" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### tracheobronchial goblet cell `http://purl.obolibrary.org/obo/CL_0019003` + +#### Added +- [tracheobronchial goblet cell](http://purl.obolibrary.org/obo/CL_0019003) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### tracheobronchial serous cell `http://purl.obolibrary.org/obo/CL_0019001` + +#### Added +- [tracheobronchial serous cell](http://purl.obolibrary.org/obo/CL_0019001) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### tracheobronchial smooth muscle cell `http://purl.obolibrary.org/obo/CL_0019019` + +#### Added +- [tracheobronchial smooth muscle cell](http://purl.obolibrary.org/obo/CL_0019019) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### tracheobronchial tree `http://purl.obolibrary.org/obo/UBERON_0007196` +#### Removed +- [tracheobronchial tree](http://purl.obolibrary.org/obo/UBERON_0007196) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "arbor tracheobronchialis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:7393" + +#### Added +- [tracheobronchial tree](http://purl.obolibrary.org/obo/UBERON_0007196) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "arbor tracheobronchialis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:7393" + + +### trans-synaptic signaling by nitric oxide `http://purl.obolibrary.org/obo/GO_0099548` +#### Removed +- [trans-synaptic signaling by nitric oxide](http://purl.obolibrary.org/obo/GO_0099548) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Cell-cell signaling between presynapse and postsynapse mediated by nitric oxide." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:dos" + +- [trans-synaptic signaling by nitric oxide](http://purl.obolibrary.org/obo/GO_0099548) [label](http://www.w3.org/2000/01/rdf-schema#label) "trans-synaptic signaling by nitric oxide" + +- [trans-synaptic signaling by nitric oxide](http://purl.obolibrary.org/obo/GO_0099548) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [trans-synaptic signaling by nitric oxide](http://purl.obolibrary.org/obo/GO_0099548) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_synapse](http://purl.obolibrary.org/obo/go#goslim_synapse) + +- [trans-synaptic signaling by nitric oxide](http://purl.obolibrary.org/obo/GO_0099548) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0099548" + +- Class: [trans-synaptic signaling by nitric oxide](http://purl.obolibrary.org/obo/GO_0099548) + +- [trans-synaptic signaling by nitric oxide](http://purl.obolibrary.org/obo/GO_0099548) EquivalentTo [trans-synaptic signaling](http://purl.obolibrary.org/obo/GO_0099537) and ([process has causal agent](http://purl.obolibrary.org/obo/RO_0002608) some [CHEBI_16480](http://purl.obolibrary.org/obo/CHEBI_16480)) + +- [trans-synaptic signaling by nitric oxide](http://purl.obolibrary.org/obo/GO_0099548) SubClassOf [trans-synaptic signaling by soluble gas](http://purl.obolibrary.org/obo/GO_0099543) + +- [trans-synaptic signaling by nitric oxide](http://purl.obolibrary.org/obo/GO_0099548) SubClassOf [synaptic signaling by nitric oxide](http://purl.obolibrary.org/obo/GO_0099163) + + + +### trans-synaptic signaling by nitric oxide, modulating synaptic transmission `http://purl.obolibrary.org/obo/GO_0099555` +#### Removed +- [trans-synaptic signaling by nitric oxide, modulating synaptic transmission](http://purl.obolibrary.org/obo/GO_0099555) [label](http://www.w3.org/2000/01/rdf-schema#label) "trans-synaptic signaling by nitric oxide, modulating synaptic transmission" + +- [trans-synaptic signaling by nitric oxide, modulating synaptic transmission](http://purl.obolibrary.org/obo/GO_0099555) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_synapse](http://purl.obolibrary.org/obo/go#goslim_synapse) + +- [trans-synaptic signaling by nitric oxide, modulating synaptic transmission](http://purl.obolibrary.org/obo/GO_0099555) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua." + +- [trans-synaptic signaling by nitric oxide, modulating synaptic transmission](http://purl.obolibrary.org/obo/GO_0099555) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [trans-synaptic signaling by nitric oxide, modulating synaptic transmission](http://purl.obolibrary.org/obo/GO_0099555) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Cell-cell signaling between presynapse and postsynapse, via the release and reception of nitric oxide molecules, that modulates the synaptic transmission properties of the synapse." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:dos" + +- [trans-synaptic signaling by nitric oxide, modulating synaptic transmission](http://purl.obolibrary.org/obo/GO_0099555) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0099555" + +- Class: [trans-synaptic signaling by nitric oxide, modulating synaptic transmission](http://purl.obolibrary.org/obo/GO_0099555) + +- [trans-synaptic signaling by nitric oxide, modulating synaptic transmission](http://purl.obolibrary.org/obo/GO_0099555) EquivalentTo [trans-synaptic signaling](http://purl.obolibrary.org/obo/GO_0099537) and ([regulates](http://purl.obolibrary.org/obo/RO_0002211) some [chemical synaptic transmission](http://purl.obolibrary.org/obo/GO_0007268)) and ([process has causal agent](http://purl.obolibrary.org/obo/RO_0002608) some [CHEBI_16480](http://purl.obolibrary.org/obo/CHEBI_16480)) + +- [trans-synaptic signaling by nitric oxide, modulating synaptic transmission](http://purl.obolibrary.org/obo/GO_0099555) SubClassOf [trans-synaptic signaling by nitric oxide](http://purl.obolibrary.org/obo/GO_0099548) + +- [trans-synaptic signaling by nitric oxide, modulating synaptic transmission](http://purl.obolibrary.org/obo/GO_0099555) SubClassOf [trans-synaptic signaling by soluble gas, modulating synaptic transmission](http://purl.obolibrary.org/obo/GO_0099554) + + + +### trans-synaptic signaling by soluble gas `http://purl.obolibrary.org/obo/GO_0099543` +#### Removed +- [trans-synaptic signaling by soluble gas](http://purl.obolibrary.org/obo/GO_0099543) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [trans-synaptic signaling by soluble gas](http://purl.obolibrary.org/obo/GO_0099543) [label](http://www.w3.org/2000/01/rdf-schema#label) "trans-synaptic signaling by soluble gas" + +- [trans-synaptic signaling by soluble gas](http://purl.obolibrary.org/obo/GO_0099543) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Cell-cell signaling between presynapse and postsynapse mediated by a soluble gas ligand crossing the synaptic cleft." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:dos" + +- [trans-synaptic signaling by soluble gas](http://purl.obolibrary.org/obo/GO_0099543) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0099543" + +- [trans-synaptic signaling by soluble gas](http://purl.obolibrary.org/obo/GO_0099543) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_synapse](http://purl.obolibrary.org/obo/go#goslim_synapse) + +- Class: [trans-synaptic signaling by soluble gas](http://purl.obolibrary.org/obo/GO_0099543) + +- [trans-synaptic signaling by soluble gas](http://purl.obolibrary.org/obo/GO_0099543) SubClassOf [trans-synaptic signaling](http://purl.obolibrary.org/obo/GO_0099537) + + + +### trans-synaptic signaling by soluble gas, modulating synaptic transmission `http://purl.obolibrary.org/obo/GO_0099554` +#### Removed +- [trans-synaptic signaling by soluble gas, modulating synaptic transmission](http://purl.obolibrary.org/obo/GO_0099554) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_synapse](http://purl.obolibrary.org/obo/go#goslim_synapse) + +- [trans-synaptic signaling by soluble gas, modulating synaptic transmission](http://purl.obolibrary.org/obo/GO_0099554) [id](http://www.geneontology.org/formats/oboInOwl#id) "GO:0099554" + +- [trans-synaptic signaling by soluble gas, modulating synaptic transmission](http://purl.obolibrary.org/obo/GO_0099554) [label](http://www.w3.org/2000/01/rdf-schema#label) "trans-synaptic signaling by soluble gas, modulating synaptic transmission" + +- [trans-synaptic signaling by soluble gas, modulating synaptic transmission](http://purl.obolibrary.org/obo/GO_0099554) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua." + +- [trans-synaptic signaling by soluble gas, modulating synaptic transmission](http://purl.obolibrary.org/obo/GO_0099554) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "biological_process" + +- [trans-synaptic signaling by soluble gas, modulating synaptic transmission](http://purl.obolibrary.org/obo/GO_0099554) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "Cell-cell signaling between presynapse and postsynapse, via the release and reception of gaseous molecules, that modulates the synaptic transmission properties of the synapse." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:dos" + +- Class: [trans-synaptic signaling by soluble gas, modulating synaptic transmission](http://purl.obolibrary.org/obo/GO_0099554) + +- [trans-synaptic signaling by soluble gas, modulating synaptic transmission](http://purl.obolibrary.org/obo/GO_0099554) SubClassOf [trans-synaptic signaling by soluble gas](http://purl.obolibrary.org/obo/GO_0099543) + +- [trans-synaptic signaling by soluble gas, modulating synaptic transmission](http://purl.obolibrary.org/obo/GO_0099554) SubClassOf [trans-synaptic signaling, modulating synaptic transmission](http://purl.obolibrary.org/obo/GO_0099550) + + + +### transferase activity `http://purl.obolibrary.org/obo/GO_0016740` +#### Removed +- [transferase activity](http://purl.obolibrary.org/obo/GO_0016740) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [prokaryote_subset](http://purl.obolibrary.org/obo/go#prokaryote_subset) + +#### Added +- [transferase activity](http://purl.obolibrary.org/obo/GO_0016740) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_prokaryote](http://purl.obolibrary.org/obo/go#goslim_prokaryote) + + +### transit amplifying cell `http://purl.obolibrary.org/obo/CL_0009010` + +#### Added +- [transit amplifying cell](http://purl.obolibrary.org/obo/CL_0009010) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### transit amplifying cell of colon `http://purl.obolibrary.org/obo/CL_0009011` + +#### Added +- [transit amplifying cell of colon](http://purl.obolibrary.org/obo/CL_0009011) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### transit amplifying cell of small intestine `http://purl.obolibrary.org/obo/CL_0009012` + +#### Added +- [transit amplifying cell of small intestine](http://purl.obolibrary.org/obo/CL_0009012) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### transitional stage B cell `http://purl.obolibrary.org/obo/CL_0000818` + +#### Added +- [transitional stage B cell](http://purl.obolibrary.org/obo/CL_0000818) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### transitively anteriorly connected to `http://purl.obolibrary.org/obo/uberon/core#transitively_anteriorly_connected_to` +#### Removed +- [transitively anteriorly connected to](http://purl.obolibrary.org/obo/uberon/core#transitively_anteriorly_connected_to) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" + +#### Added +- [transitively anteriorly connected to](http://purl.obolibrary.org/obo/uberon/core#transitively_anteriorly_connected_to) [see also](http://www.w3.org/2000/01/rdf-schema#seeAlso) "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + + +### transitively distally connected to `http://purl.obolibrary.org/obo/uberon/core#transitively_distally_connected_to` +#### Removed +- [transitively distally connected to](http://purl.obolibrary.org/obo/uberon/core#transitively_distally_connected_to) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" + +#### Added +- [transitively distally connected to](http://purl.obolibrary.org/obo/uberon/core#transitively_distally_connected_to) [see also](http://www.w3.org/2000/01/rdf-schema#seeAlso) "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + + +### transitively proximally connected to `http://purl.obolibrary.org/obo/uberon/core#transitively_proximally_connected_to` +#### Removed +- [transitively proximally connected to](http://purl.obolibrary.org/obo/uberon/core#transitively_proximally_connected_to) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" + +#### Added +- [transitively proximally connected to](http://purl.obolibrary.org/obo/uberon/core#transitively_proximally_connected_to) [see also](http://www.w3.org/2000/01/rdf-schema#seeAlso) "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + + +### translation `http://purl.obolibrary.org/obo/GO_0006412` +#### Removed +- [translation](http://purl.obolibrary.org/obo/GO_0006412) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [prokaryote_subset](http://purl.obolibrary.org/obo/go#prokaryote_subset) + +#### Added +- [translation](http://purl.obolibrary.org/obo/GO_0006412) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_prokaryote](http://purl.obolibrary.org/obo/go#goslim_prokaryote) + + +### transport `http://purl.obolibrary.org/obo/GO_0006810` +#### Removed +- [transport](http://purl.obolibrary.org/obo/GO_0006810) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [prokaryote_subset](http://purl.obolibrary.org/obo/go#prokaryote_subset) + +#### Added +- [transport](http://purl.obolibrary.org/obo/GO_0006810) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_prokaryote](http://purl.obolibrary.org/obo/go#goslim_prokaryote) + + +### transporter activity `http://purl.obolibrary.org/obo/GO_0005215` +#### Removed +- [transporter activity](http://purl.obolibrary.org/obo/GO_0005215) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [prokaryote_subset](http://purl.obolibrary.org/obo/go#prokaryote_subset) + +#### Added +- [transporter activity](http://purl.obolibrary.org/obo/GO_0005215) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [goslim_prokaryote](http://purl.obolibrary.org/obo/go#goslim_prokaryote) + + +### transverse colon `http://purl.obolibrary.org/obo/UBERON_0001157` +#### Removed +- [transverse colon](http://purl.obolibrary.org/obo/UBERON_0001157) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D044684" + +- [transverse colon](http://purl.obolibrary.org/obo/UBERON_0001157) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "colon transversum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Transverse_colon" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [transverse colon](http://purl.obolibrary.org/obo/UBERON_0001157) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "colon transversum" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Transverse_colon" + +- [transverse colon](http://purl.obolibrary.org/obo/UBERON_0001157) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D044684" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [author_id](https://w3id.org/sssom/author_id) [0000-0001-9439-5346](https://orcid.org/0000-0001-9439-5346) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + + +### trapezius muscle `http://purl.obolibrary.org/obo/UBERON_0002380` +#### Removed +- [trapezius muscle](http://purl.obolibrary.org/obo/UBERON_0002380) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "musculus trapezius" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Trapezius_muscle" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [trapezius muscle](http://purl.obolibrary.org/obo/UBERON_0002380) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "musculus trapezius" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Trapezius_muscle" + + +### trigeminal ganglion `http://purl.obolibrary.org/obo/UBERON_0001675` +#### Removed +- [trigeminal ganglion](http://purl.obolibrary.org/obo/UBERON_0001675) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ganglion semilunare" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Trigeminal_ganglion" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [trigeminal ganglion](http://purl.obolibrary.org/obo/UBERON_0001675) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ganglion trigeminale" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Trigeminal_ganglion" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0001231" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [trigeminal ganglion](http://purl.obolibrary.org/obo/UBERON_0001675) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ganglion semilunare" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Trigeminal_ganglion" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [trigeminal ganglion](http://purl.obolibrary.org/obo/UBERON_0001675) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ganglion trigeminale" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Trigeminal_ganglion" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0001231" + + +### trigeminal nerve `http://purl.obolibrary.org/obo/UBERON_0001645` +#### Removed +- [trigeminal nerve](http://purl.obolibrary.org/obo/UBERON_0001645) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nervus trigeminus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Trigeminal_nerve" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [trigeminal nerve](http://purl.obolibrary.org/obo/UBERON_0001645) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nervus trigeminus [v]" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:50866" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + +#### Added +- [trigeminal nerve](http://purl.obolibrary.org/obo/UBERON_0001645) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nervus trigeminus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Trigeminal_nerve" + +- [trigeminal nerve](http://purl.obolibrary.org/obo/UBERON_0001645) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nervus trigeminus [v]" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:50866" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + +### trigeminal nerve fibers `http://purl.obolibrary.org/obo/UBERON_0003041` +#### Removed +- [trigeminal nerve fibers](http://purl.obolibrary.org/obo/UBERON_0003041) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "fibrae nervi trigemini" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:607" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [trigeminal nerve fibers](http://purl.obolibrary.org/obo/UBERON_0003041) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "fibrae nervi trigemini" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:607" + + +### trigeminal nerve root `http://purl.obolibrary.org/obo/UBERON_0004673` +#### Removed +- [trigeminal nerve root](http://purl.obolibrary.org/obo/UBERON_0004673) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "radix descendens nervi trigemini" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ZFA:0000192" + +#### Added +- [trigeminal nerve root](http://purl.obolibrary.org/obo/UBERON_0004673) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "radix descendens nervi trigemini" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ZFA:0000192" + + +### trigeminal nuclear complex `http://purl.obolibrary.org/obo/UBERON_0007641` +#### Removed +- [trigeminal nuclear complex](http://purl.obolibrary.org/obo/UBERON_0007641) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nuclei trigemini" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Trigeminal_nerve_nuclei" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [trigeminal nuclear complex](http://purl.obolibrary.org/obo/UBERON_0007641) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D014278" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [LexicalMatching](https://w3id.org/semapv/vocab/LexicalMatching) + + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + +- [trigeminal nuclear complex](http://purl.obolibrary.org/obo/UBERON_0007641) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nuclei trigemini" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Trigeminal_nerve_nuclei" + + +### trigone of urinary bladder `http://purl.obolibrary.org/obo/UBERON_0001257` +#### Removed +- [trigone of urinary bladder](http://purl.obolibrary.org/obo/UBERON_0001257) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "musculus trigoni vesicae profundus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:15910" + +- [trigone of urinary bladder](http://purl.obolibrary.org/obo/UBERON_0001257) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "trigonum vesicae urinariae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Trigone_of_urinary_bladder" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [trigone of urinary bladder](http://purl.obolibrary.org/obo/UBERON_0001257) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "trigonum vesicae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:15910" + +#### Added +- [trigone of urinary bladder](http://purl.obolibrary.org/obo/UBERON_0001257) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "trigonum vesicae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:15910" + +- [trigone of urinary bladder](http://purl.obolibrary.org/obo/UBERON_0001257) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "trigonum vesicae urinariae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Trigone_of_urinary_bladder" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + +- [trigone of urinary bladder](http://purl.obolibrary.org/obo/UBERON_0001257) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "musculus trigoni vesicae profundus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:15910" + + +### trophoblast `http://purl.obolibrary.org/obo/UBERON_0000088` +#### Removed +- [trophoblast](http://purl.obolibrary.org/obo/UBERON_0000088) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "trophoblastus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Trophoblast" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [trophoblast](http://purl.obolibrary.org/obo/UBERON_0000088) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "massa cellularis externa" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Trophoblast" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [trophoblast](http://purl.obolibrary.org/obo/UBERON_0000088) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "massa cellularis externa" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Trophoblast" + +- [trophoblast](http://purl.obolibrary.org/obo/UBERON_0000088) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "trophoblastus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Trophoblast" + + +### trophoblast giant cell `http://purl.obolibrary.org/obo/CL_0002488` + +#### Added +- [trophoblast giant cell](http://purl.obolibrary.org/obo/CL_0002488) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### tuft cell of colon `http://purl.obolibrary.org/obo/CL_0009041` + +#### Added +- [tuft cell of colon](http://purl.obolibrary.org/obo/CL_0009041) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) + + +### tunica adventitia of blood vessel `http://purl.obolibrary.org/obo/UBERON_0005734` +#### Removed +- [tunica adventitia of blood vessel](http://purl.obolibrary.org/obo/UBERON_0005734) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tunica externa vasorum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Tunica_externa_(vessels)" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [tunica adventitia of blood vessel](http://purl.obolibrary.org/obo/UBERON_0005734) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tunica adventitia vasorum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Tunica_externa_(vessels)" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +#### Added +- [tunica adventitia of blood vessel](http://purl.obolibrary.org/obo/UBERON_0005734) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tunica externa vasorum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Tunica_externa_(vessels)" -- [Callithrix jacchus](http://purl.obolibrary.org/obo/NCBITaxon_9483) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "common marmoset" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [common_name](http://purl.obolibrary.org/obo/ncbitaxon#common_name) + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) -#### Added -- [Callithrix jacchus](http://purl.obolibrary.org/obo/NCBITaxon_9483) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "white ear-tufted marmoset" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003003](http://purl.obolibrary.org/obo/OMO_0003003) +- [tunica adventitia of blood vessel](http://purl.obolibrary.org/obo/UBERON_0005734) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tunica adventitia vasorum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Tunica_externa_(vessels)" -- [Callithrix jacchus](http://purl.obolibrary.org/obo/NCBITaxon_9483) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "common marmoset" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003003](http://purl.obolibrary.org/obo/OMO_0003003) + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) -### Cnidaria `http://purl.obolibrary.org/obo/NCBITaxon_6073` +### tunica media `http://purl.obolibrary.org/obo/UBERON_0002522` #### Removed -- [Cnidaria](http://purl.obolibrary.org/obo/NCBITaxon_6073) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "coelenterates" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [common_name](http://purl.obolibrary.org/obo/ncbitaxon#common_name) - -#### Added -- [Cnidaria](http://purl.obolibrary.org/obo/NCBITaxon_6073) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "coelenterates" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003003](http://purl.obolibrary.org/obo/OMO_0003003) +- [tunica media](http://purl.obolibrary.org/obo/UBERON_0002522) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tunica media vasorum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Tunica_media" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) -### Deuterostomia `http://purl.obolibrary.org/obo/NCBITaxon_33511` -#### Removed -- [Deuterostomia](http://purl.obolibrary.org/obo/NCBITaxon_33511) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "deuterostomes" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [common_name](http://purl.obolibrary.org/obo/ncbitaxon#common_name) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0002011" #### Added -- [Deuterostomia](http://purl.obolibrary.org/obo/NCBITaxon_33511) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "deuterostomes" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003003](http://purl.obolibrary.org/obo/OMO_0003003) +- [tunica media](http://purl.obolibrary.org/obo/UBERON_0002522) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tunica media vasorum" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Tunica_media" -### Dinosauria `http://purl.obolibrary.org/obo/NCBITaxon_436486` + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0002011" + + +### tympanic cavity `http://purl.obolibrary.org/obo/UBERON_0004114` #### Removed -- [Dinosauria](http://purl.obolibrary.org/obo/NCBITaxon_436486) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "dinosaurs" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [common_name](http://purl.obolibrary.org/obo/ncbitaxon#common_name) +- [tympanic cavity](http://purl.obolibrary.org/obo/UBERON_0004114) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cavitas tympani" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Tympanic_cavity" -- [Dinosauria](http://purl.obolibrary.org/obo/NCBITaxon_436486) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "dinosaur" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [common_name](http://purl.obolibrary.org/obo/ncbitaxon#common_name) + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) #### Added -- [Dinosauria](http://purl.obolibrary.org/obo/NCBITaxon_436486) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "dinosaurs" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003003](http://purl.obolibrary.org/obo/OMO_0003003) +- [tympanic cavity](http://purl.obolibrary.org/obo/UBERON_0004114) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cavitas tympani" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) -- [Dinosauria](http://purl.obolibrary.org/obo/NCBITaxon_436486) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "dinosaur" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003003](http://purl.obolibrary.org/obo/OMO_0003003) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Tympanic_cavity" -### Embryophyta `http://purl.obolibrary.org/obo/NCBITaxon_3193` +### tympanic membrane `http://purl.obolibrary.org/obo/UBERON_0002364` #### Removed -- [Embryophyta](http://purl.obolibrary.org/obo/NCBITaxon_3193) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "plants" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [common_name](http://purl.obolibrary.org/obo/ncbitaxon#common_name) +- [tympanic membrane](http://purl.obolibrary.org/obo/UBERON_0002364) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "paries membranaceus cavi tympani" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:9595" -- [Embryophyta](http://purl.obolibrary.org/obo/NCBITaxon_3193) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "land plants" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [common_name](http://purl.obolibrary.org/obo/ncbitaxon#common_name) + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) -- [Embryophyta](http://purl.obolibrary.org/obo/NCBITaxon_3193) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "higher plants" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [common_name](http://purl.obolibrary.org/obo/ncbitaxon#common_name) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" #### Added -- [Embryophyta](http://purl.obolibrary.org/obo/NCBITaxon_3193) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "plants" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003003](http://purl.obolibrary.org/obo/OMO_0003003) +- [tympanic membrane](http://purl.obolibrary.org/obo/UBERON_0002364) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "paries membranaceus cavi tympani" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) -- [Embryophyta](http://purl.obolibrary.org/obo/NCBITaxon_3193) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "land plants" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003003](http://purl.obolibrary.org/obo/OMO_0003003) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:9595" -- [Embryophyta](http://purl.obolibrary.org/obo/NCBITaxon_3193) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "higher plants" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003003](http://purl.obolibrary.org/obo/OMO_0003003) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" -### Eukaryota `http://purl.obolibrary.org/obo/NCBITaxon_2759` -#### Removed -- [Eukaryota](http://purl.obolibrary.org/obo/NCBITaxon_2759) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "eukaryotes" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [common_name](http://purl.obolibrary.org/obo/ncbitaxon#common_name) +### type B pancreatic cell `http://purl.obolibrary.org/obo/CL_0000169` #### Added -- [Eukaryota](http://purl.obolibrary.org/obo/NCBITaxon_2759) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "eukaryotes" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003003](http://purl.obolibrary.org/obo/OMO_0003003) - +- [type B pancreatic cell](http://purl.obolibrary.org/obo/CL_0000169) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) -### Eutheria `http://purl.obolibrary.org/obo/NCBITaxon_9347` -#### Removed -- [Eutheria](http://purl.obolibrary.org/obo/NCBITaxon_9347) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "placental mammals" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [common_name](http://purl.obolibrary.org/obo/ncbitaxon#common_name) -- [Eutheria](http://purl.obolibrary.org/obo/NCBITaxon_9347) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "eutherian mammals" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [common_name](http://purl.obolibrary.org/obo/ncbitaxon#common_name) +### type D enteroendocrine cell `http://purl.obolibrary.org/obo/CL_0000502` #### Added -- [Eutheria](http://purl.obolibrary.org/obo/NCBITaxon_9347) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "eutherian mammals" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003003](http://purl.obolibrary.org/obo/OMO_0003003) +- [type D enteroendocrine cell](http://purl.obolibrary.org/obo/CL_0000502) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) -- [Eutheria](http://purl.obolibrary.org/obo/NCBITaxon_9347) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "placental mammals" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003003](http://purl.obolibrary.org/obo/OMO_0003003) +### type EC enteroendocrine cell `http://purl.obolibrary.org/obo/CL_0000577` -### Felis catus `http://purl.obolibrary.org/obo/NCBITaxon_9685` -#### Removed -- [Felis catus](http://purl.obolibrary.org/obo/NCBITaxon_9685) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cat" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [common_name](http://purl.obolibrary.org/obo/ncbitaxon#common_name) +#### Added +- [type EC enteroendocrine cell](http://purl.obolibrary.org/obo/CL_0000577) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) -- [Felis catus](http://purl.obolibrary.org/obo/NCBITaxon_9685) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cats" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [common_name](http://purl.obolibrary.org/obo/ncbitaxon#common_name) -#### Added -- [Felis catus](http://purl.obolibrary.org/obo/NCBITaxon_9685) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cat" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003003](http://purl.obolibrary.org/obo/OMO_0003003) +### type G enteroendocrine cell `http://purl.obolibrary.org/obo/CL_0000508` -- [Felis catus](http://purl.obolibrary.org/obo/NCBITaxon_9685) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cats" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003003](http://purl.obolibrary.org/obo/OMO_0003003) +#### Added +- [type G enteroendocrine cell](http://purl.obolibrary.org/obo/CL_0000508) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) -### GCIs +### type I NK T cell `http://purl.obolibrary.org/obo/CL_0000921` #### Added -- [cranial suture](http://purl.obolibrary.org/obo/UBERON_0003685) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [Mammalia](http://purl.obolibrary.org/obo/NCBITaxon_40674)) SubClassOf [developmentally induced by](http://purl.obolibrary.org/obo/RO_0002256) some [dura mater](http://purl.obolibrary.org/obo/UBERON_0002363) - - [source](http://www.geneontology.org/formats/oboInOwl#source) "PMID:16496288" +- [type I NK T cell](http://purl.obolibrary.org/obo/CL_0000921) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) -### Glaucocystophyceae `http://purl.obolibrary.org/obo/NCBITaxon_38254` -#### Removed -- [Glaucocystophyceae](http://purl.obolibrary.org/obo/NCBITaxon_38254) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "glaucocystophytes" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [common_name](http://purl.obolibrary.org/obo/ncbitaxon#common_name) +### type I enteroendocrine cell `http://purl.obolibrary.org/obo/CL_0002277` #### Added -- [Glaucocystophyceae](http://purl.obolibrary.org/obo/NCBITaxon_38254) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "glaucocystophytes" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003003](http://purl.obolibrary.org/obo/OMO_0003003) +- [type I enteroendocrine cell](http://purl.obolibrary.org/obo/CL_0002277) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) -### Hominoidea `http://purl.obolibrary.org/obo/NCBITaxon_314295` -#### Removed -- [Hominoidea](http://purl.obolibrary.org/obo/NCBITaxon_314295) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ape" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [common_name](http://purl.obolibrary.org/obo/ncbitaxon#common_name) +### type I pneumocyte `http://purl.obolibrary.org/obo/CL_0002062` #### Added -- [Hominoidea](http://purl.obolibrary.org/obo/NCBITaxon_314295) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ape" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003003](http://purl.obolibrary.org/obo/OMO_0003003) +- [type I pneumocyte](http://purl.obolibrary.org/obo/CL_0002062) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) -### Homo `http://purl.obolibrary.org/obo/NCBITaxon_9605` -#### Removed -- [Homo](http://purl.obolibrary.org/obo/NCBITaxon_9605) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "humans" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [common_name](http://purl.obolibrary.org/obo/ncbitaxon#common_name) +### type II NK T cell `http://purl.obolibrary.org/obo/CL_0000922` #### Added -- [Homo](http://purl.obolibrary.org/obo/NCBITaxon_9605) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "humans" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003003](http://purl.obolibrary.org/obo/OMO_0003003) +- [type II NK T cell](http://purl.obolibrary.org/obo/CL_0000922) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) -### Magnoliopsida `http://purl.obolibrary.org/obo/NCBITaxon_3398` -#### Removed -- [Magnoliopsida](http://purl.obolibrary.org/obo/NCBITaxon_3398) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "angiosperms" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [common_name](http://purl.obolibrary.org/obo/ncbitaxon#common_name) +### type II pneumocyte `http://purl.obolibrary.org/obo/CL_0002063` #### Added -- [Magnoliopsida](http://purl.obolibrary.org/obo/NCBITaxon_3398) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "angiosperms" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003003](http://purl.obolibrary.org/obo/OMO_0003003) +- [type II pneumocyte](http://purl.obolibrary.org/obo/CL_0002063) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) -### Mandibulata `http://purl.obolibrary.org/obo/NCBITaxon_197563` -#### Removed -- [Mandibulata](http://purl.obolibrary.org/obo/NCBITaxon_197563) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "mandibulates" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [common_name](http://purl.obolibrary.org/obo/ncbitaxon#common_name) +### type L enteroendocrine cell `http://purl.obolibrary.org/obo/CL_0002279` #### Added -- [Mandibulata](http://purl.obolibrary.org/obo/NCBITaxon_197563) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "mandibulates" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003003](http://purl.obolibrary.org/obo/OMO_0003003) +- [type L enteroendocrine cell](http://purl.obolibrary.org/obo/CL_0002279) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) -### Metazoa `http://purl.obolibrary.org/obo/NCBITaxon_33208` -#### Removed -- [Metazoa](http://purl.obolibrary.org/obo/NCBITaxon_33208) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "multicellular animals" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [common_name](http://purl.obolibrary.org/obo/ncbitaxon#common_name) +### type N enteroendocrine cell `http://purl.obolibrary.org/obo/CL_0002280` #### Added -- [Metazoa](http://purl.obolibrary.org/obo/NCBITaxon_33208) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "multicellular animals" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003003](http://purl.obolibrary.org/obo/OMO_0003003) +- [type N enteroendocrine cell](http://purl.obolibrary.org/obo/CL_0002280) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) -### Mus `http://purl.obolibrary.org/obo/NCBITaxon_10088` +### umbilical artery `http://purl.obolibrary.org/obo/UBERON_0001310` #### Removed -- [Mus ](http://purl.obolibrary.org/obo/NCBITaxon_10088) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "mice" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [common_name](http://purl.obolibrary.org/obo/ncbitaxon#common_name) +- [umbilical artery](http://purl.obolibrary.org/obo/UBERON_0001310) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "a. umbilicalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Umbilical_artery" -- [Mus ](http://purl.obolibrary.org/obo/NCBITaxon_10088) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "mouse" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [common_name](http://purl.obolibrary.org/obo/ncbitaxon#common_name) + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) #### Added -- [Mus ](http://purl.obolibrary.org/obo/NCBITaxon_10088) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "mice" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003003](http://purl.obolibrary.org/obo/OMO_0003003) +- [umbilical artery](http://purl.obolibrary.org/obo/UBERON_0001310) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "a. umbilicalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) -- [Mus ](http://purl.obolibrary.org/obo/NCBITaxon_10088) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "mouse" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003003](http://purl.obolibrary.org/obo/OMO_0003003) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Umbilical_artery" -### Mus musculus `http://purl.obolibrary.org/obo/NCBITaxon_10090` +### umbilical cord `http://purl.obolibrary.org/obo/UBERON_0002331` #### Removed -- [Mus musculus](http://purl.obolibrary.org/obo/NCBITaxon_10090) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "mouse" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [common_name](http://purl.obolibrary.org/obo/ncbitaxon#common_name) +- [umbilical cord](http://purl.obolibrary.org/obo/UBERON_0002331) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "funiculus umbilicalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MP:0012134" -#### Added -- [Mus musculus](http://purl.obolibrary.org/obo/NCBITaxon_10090) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "mouse" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003003](http://purl.obolibrary.org/obo/OMO_0003003) + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) +- [umbilical cord](http://purl.obolibrary.org/obo/UBERON_0002331) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "chorda umbilicalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MP:0012134" -### Nematoda `http://purl.obolibrary.org/obo/NCBITaxon_6231` -#### Removed -- [Nematoda](http://purl.obolibrary.org/obo/NCBITaxon_6231) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "roundworm" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [common_name](http://purl.obolibrary.org/obo/ncbitaxon#common_name) + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) -- [Nematoda](http://purl.obolibrary.org/obo/NCBITaxon_6231) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nematodes" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [common_name](http://purl.obolibrary.org/obo/ncbitaxon#common_name) +- [umbilical cord](http://purl.obolibrary.org/obo/UBERON_0002331) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "funiculus umbilicalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Umbilical_cord" -- [Nematoda](http://purl.obolibrary.org/obo/NCBITaxon_6231) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nematode" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [common_name](http://purl.obolibrary.org/obo/ncbitaxon#common_name) + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) #### Added -- [Nematoda](http://purl.obolibrary.org/obo/NCBITaxon_6231) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nematode" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003003](http://purl.obolibrary.org/obo/OMO_0003003) +- [umbilical cord](http://purl.obolibrary.org/obo/UBERON_0002331) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "chorda umbilicalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MP:0012134" -- [Nematoda](http://purl.obolibrary.org/obo/NCBITaxon_6231) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nematodes" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003003](http://purl.obolibrary.org/obo/OMO_0003003) + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) -- [Nematoda](http://purl.obolibrary.org/obo/NCBITaxon_6231) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "roundworm" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003003](http://purl.obolibrary.org/obo/OMO_0003003) +- [umbilical cord](http://purl.obolibrary.org/obo/UBERON_0002331) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "funiculus umbilicalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Umbilical_cord" -### OMO_0003003 `http://purl.obolibrary.org/obo/OMO_0003003` - -#### Added -- AnnotationProperty: [OMO_0003003](http://purl.obolibrary.org/obo/OMO_0003003) +- [umbilical cord](http://purl.obolibrary.org/obo/UBERON_0002331) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "funiculus umbilicalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MP:0012134" -- [OMO_0003003](http://purl.obolibrary.org/obo/OMO_0003003) SubPropertyOf: [synonym_type_property](http://www.geneontology.org/formats/oboInOwl#SynonymTypeProperty) + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) -### Platyhelminthes `http://purl.obolibrary.org/obo/NCBITaxon_6157` +### umbilical vein `http://purl.obolibrary.org/obo/UBERON_0002066` #### Removed -- [Platyhelminthes](http://purl.obolibrary.org/obo/NCBITaxon_6157) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "flatworm" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [common_name](http://purl.obolibrary.org/obo/ncbitaxon#common_name) +- [umbilical vein](http://purl.obolibrary.org/obo/UBERON_0002066) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vena umbilicalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Umbilical_vein" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) #### Added -- [Platyhelminthes](http://purl.obolibrary.org/obo/NCBITaxon_6157) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "flatworm" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003003](http://purl.obolibrary.org/obo/OMO_0003003) +- [umbilical vein](http://purl.obolibrary.org/obo/UBERON_0002066) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vena umbilicalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Umbilical_vein" -### Platyrrhini `http://purl.obolibrary.org/obo/NCBITaxon_9479` +### undifferentiated genital tubercle `http://purl.obolibrary.org/obo/UBERON_0005876` #### Removed -- [Platyrrhini](http://purl.obolibrary.org/obo/NCBITaxon_9479) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "monkeys" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [common_name](http://purl.obolibrary.org/obo/ncbitaxon#common_name) +- [undifferentiated genital tubercle](http://purl.obolibrary.org/obo/UBERON_0005876) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tuberculum phallicum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Genital_tubercle" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + +- [undifferentiated genital tubercle](http://purl.obolibrary.org/obo/UBERON_0005876) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tuberculum genitale" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Genital_tubercle" -- [Platyrrhini](http://purl.obolibrary.org/obo/NCBITaxon_9479) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "monkey" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [common_name](http://purl.obolibrary.org/obo/ncbitaxon#common_name) + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) #### Added -- [Platyrrhini](http://purl.obolibrary.org/obo/NCBITaxon_9479) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "monkey" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003003](http://purl.obolibrary.org/obo/OMO_0003003) +- [undifferentiated genital tubercle](http://purl.obolibrary.org/obo/UBERON_0005876) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tuberculum phallicum" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) -- [Platyrrhini](http://purl.obolibrary.org/obo/NCBITaxon_9479) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "monkeys" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003003](http://purl.obolibrary.org/obo/OMO_0003003) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Genital_tubercle" +- [undifferentiated genital tubercle](http://purl.obolibrary.org/obo/UBERON_0005876) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tuberculum genitale" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) -### Rhabditida `http://purl.obolibrary.org/obo/NCBITaxon_6236` + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Genital_tubercle" -#### Added -- [Rhabditida](http://purl.obolibrary.org/obo/NCBITaxon_6236) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "NCBITaxon:6308" -- [Rhabditida](http://purl.obolibrary.org/obo/NCBITaxon_6236) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Strongylida" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [synonym](http://purl.obolibrary.org/obo/ncbitaxon#synonym) +### unswitched memory B cell `http://purl.obolibrary.org/obo/CL_0000970` + +#### Added +- [unswitched memory B cell](http://purl.obolibrary.org/obo/CL_0000970) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) -### Saccharomyces cerevisiae `http://purl.obolibrary.org/obo/NCBITaxon_4932` +### upper lip `http://purl.obolibrary.org/obo/UBERON_0001834` #### Removed -- [Saccharomyces cerevisiae](http://purl.obolibrary.org/obo/NCBITaxon_4932) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "baker's yeast" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [genbank_common_name](http://purl.obolibrary.org/obo/ncbitaxon#genbank_common_name) - -- [Saccharomyces cerevisiae](http://purl.obolibrary.org/obo/NCBITaxon_4932) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "brewer's yeast" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [common_name](http://purl.obolibrary.org/obo/ncbitaxon#common_name) +- [upper lip](http://purl.obolibrary.org/obo/UBERON_0001834) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "labium superius oris" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) -- [Saccharomyces cerevisiae](http://purl.obolibrary.org/obo/NCBITaxon_4932) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "S. cerevisiae" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [common_name](http://purl.obolibrary.org/obo/ncbitaxon#common_name) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Upper_lip" #### Added -- [Saccharomyces cerevisiae](http://purl.obolibrary.org/obo/NCBITaxon_4932) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "Saccharomyces diastaticus" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [synonym](http://purl.obolibrary.org/obo/ncbitaxon#synonym) +- [upper lip](http://purl.obolibrary.org/obo/UBERON_0001834) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "labium superius oris" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) -- [Saccharomyces cerevisiae](http://purl.obolibrary.org/obo/NCBITaxon_4932) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "Saccharomyces cerevisiae 'var. diastaticus'" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [equivalent_name](http://purl.obolibrary.org/obo/ncbitaxon#equivalent_name) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Upper_lip" -- [Saccharomyces cerevisiae](http://purl.obolibrary.org/obo/NCBITaxon_4932) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "baker's yeast" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003003](http://purl.obolibrary.org/obo/OMO_0003003) -- [Saccharomyces cerevisiae](http://purl.obolibrary.org/obo/NCBITaxon_4932) [has_alternative_id](http://www.geneontology.org/formats/oboInOwl#hasAlternativeId) "NCBITaxon:41870" +### ureteric bud `http://purl.obolibrary.org/obo/UBERON_0000084` +#### Removed +- [ureteric bud](http://purl.obolibrary.org/obo/UBERON_0000084) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "gemma ureterica" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Ureteric_bud" -- [Saccharomyces cerevisiae](http://purl.obolibrary.org/obo/NCBITaxon_4932) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "brewer's yeast" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [genbank_common_name](http://purl.obolibrary.org/obo/ncbitaxon#genbank_common_name) + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) +- [ureteric bud](http://purl.obolibrary.org/obo/UBERON_0000084) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "diverticulum metanephricum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Ureteric_bud" -### Spermatophyta `http://purl.obolibrary.org/obo/NCBITaxon_58024` -#### Removed -- [Spermatophyta](http://purl.obolibrary.org/obo/NCBITaxon_58024) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "seed plants" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [common_name](http://purl.obolibrary.org/obo/ncbitaxon#common_name) + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) #### Added -- [Spermatophyta](http://purl.obolibrary.org/obo/NCBITaxon_58024) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "seed plants" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003003](http://purl.obolibrary.org/obo/OMO_0003003) +- [ureteric bud](http://purl.obolibrary.org/obo/UBERON_0000084) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "gemma ureterica" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Ureteric_bud" -### Tracheophyta `http://purl.obolibrary.org/obo/NCBITaxon_58023` -#### Removed -- [Tracheophyta](http://purl.obolibrary.org/obo/NCBITaxon_58023) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "vascular plants" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [common_name](http://purl.obolibrary.org/obo/ncbitaxon#common_name) +- [ureteric bud](http://purl.obolibrary.org/obo/UBERON_0000084) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "diverticulum metanephricum" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) -#### Added -- [Tracheophyta](http://purl.obolibrary.org/obo/NCBITaxon_58023) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "vascular plants" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003003](http://purl.obolibrary.org/obo/OMO_0003003) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Ureteric_bud" -### Viridiplantae `http://purl.obolibrary.org/obo/NCBITaxon_33090` +### urethra smooth muscle layer `http://purl.obolibrary.org/obo/UBERON_0004219` #### Removed -- [Viridiplantae](http://purl.obolibrary.org/obo/NCBITaxon_33090) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "green plants" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [common_name](http://purl.obolibrary.org/obo/ncbitaxon#common_name) +- [urethra smooth muscle layer](http://purl.obolibrary.org/obo/UBERON_0004219) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica muscularis urethrae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" #### Added -- [Viridiplantae](http://purl.obolibrary.org/obo/NCBITaxon_33090) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "green plants" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003003](http://purl.obolibrary.org/obo/OMO_0003003) +- [urethra smooth muscle layer](http://purl.obolibrary.org/obo/UBERON_0004219) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "tunica muscularis urethrae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" -### Zygnemophyceae `http://purl.obolibrary.org/obo/NCBITaxon_131209` -#### Removed -- [Zygnemophyceae](http://purl.obolibrary.org/obo/NCBITaxon_131209) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "gamophytes" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [common_name](http://purl.obolibrary.org/obo/ncbitaxon#common_name) + +### urethra urothelial cell `http://purl.obolibrary.org/obo/CL_1001430` #### Added -- [Zygnemophyceae](http://purl.obolibrary.org/obo/NCBITaxon_131209) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "gamophytes" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003003](http://purl.obolibrary.org/obo/OMO_0003003) +- [urethra urothelial cell](http://purl.obolibrary.org/obo/CL_1001430) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) -### adrenal tissue `http://purl.obolibrary.org/obo/UBERON_0018303` +### urethral artery `http://purl.obolibrary.org/obo/UBERON_0039355` #### Removed -- [adrenal tissue](http://purl.obolibrary.org/obo/UBERON_0018303) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UBERONTEMP:a7bf197b-0db2-467e-824e-be45b39e2672" - +- [urethral artery](http://purl.obolibrary.org/obo/UBERON_0039355) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "arteria urethralis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "A12.2.15.042" - -### anatomical entity `http://purl.obolibrary.org/obo/UBERON_0001062` + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) #### Added -- [anatomical entity](http://purl.obolibrary.org/obo/UBERON_0001062) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BFO:0000004" +- [urethral artery](http://purl.obolibrary.org/obo/UBERON_0039355) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "arteria urethralis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "A12.2.15.042" -### anatomical surface region `http://purl.obolibrary.org/obo/UBERON_0036215` + +### urethral meatus `http://purl.obolibrary.org/obo/UBERON_0012240` #### Removed -- [anatomical surface region](http://purl.obolibrary.org/obo/UBERON_0036215) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "AEO:0000154" +- [urethral meatus](http://purl.obolibrary.org/obo/UBERON_0012240) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "orificium urethrae externum" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) +- [urethral meatus](http://purl.obolibrary.org/obo/UBERON_0012240) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "orificium urethræ externum" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) +- [urethral meatus](http://purl.obolibrary.org/obo/UBERON_0012240) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "meatus urinarius" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) -### artery of lower lip `http://purl.obolibrary.org/obo/UBERON_0003471` -#### Removed -- [artery of lower lip](http://purl.obolibrary.org/obo/UBERON_0003471) SubClassOf [systemic artery](http://purl.obolibrary.org/obo/UBERON_0004573) +#### Added +- [urethral meatus](http://purl.obolibrary.org/obo/UBERON_0012240) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "orificium urethræ externum" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) -- [artery of lower lip](http://purl.obolibrary.org/obo/UBERON_0003471) SubClassOf [branching part of](http://purl.obolibrary.org/obo/RO_0002380) some [facial artery](http://purl.obolibrary.org/obo/UBERON_0001612) - - [source](http://www.geneontology.org/formats/oboInOwl#source) "FMA" +- [urethral meatus](http://purl.obolibrary.org/obo/UBERON_0012240) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "meatus urinarius" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) -#### Added -- [artery of lower lip](http://purl.obolibrary.org/obo/UBERON_0003471) SubClassOf [connecting branch of](http://purl.obolibrary.org/obo/RO_0002252) some [facial artery](http://purl.obolibrary.org/obo/UBERON_0001612) - - [source](http://www.geneontology.org/formats/oboInOwl#source) "FMA" +- [urethral meatus](http://purl.obolibrary.org/obo/UBERON_0012240) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "orificium urethrae externum" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) -### artery of upper lip `http://purl.obolibrary.org/obo/UBERON_0003470` +### urinary bladder `http://purl.obolibrary.org/obo/UBERON_0001255` #### Removed -- [artery of upper lip](http://purl.obolibrary.org/obo/UBERON_0003470) SubClassOf [systemic artery](http://purl.obolibrary.org/obo/UBERON_0004573) +- [urinary bladder](http://purl.obolibrary.org/obo/UBERON_0001255) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "vesica urinaria" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Urinary_bladder" -- [artery of upper lip](http://purl.obolibrary.org/obo/UBERON_0003470) SubClassOf [branching part of](http://purl.obolibrary.org/obo/RO_0002380) some [facial artery](http://purl.obolibrary.org/obo/UBERON_0001612) - - [source](http://www.geneontology.org/formats/oboInOwl#source) "FMA" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) #### Added -- [artery of upper lip](http://purl.obolibrary.org/obo/UBERON_0003470) SubClassOf [connecting branch of](http://purl.obolibrary.org/obo/RO_0002252) some [facial artery](http://purl.obolibrary.org/obo/UBERON_0001612) - - [source](http://www.geneontology.org/formats/oboInOwl#source) "FMA" +- [urinary bladder](http://purl.obolibrary.org/obo/UBERON_0001255) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "vesica urinaria" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Urinary_bladder" - -### axial skeletal system `http://purl.obolibrary.org/obo/UBERON_0011137` -#### Removed -- [axial skeletal system](http://purl.obolibrary.org/obo/UBERON_0011137) SubClassOf [has part](http://purl.obolibrary.org/obo/BFO_0000051) some [axial skeleton plus cranial skeleton](http://purl.obolibrary.org/obo/UBERON_0005944) + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) +### urorectal septum `http://purl.obolibrary.org/obo/UBERON_0005760` +#### Removed +- [urorectal septum](http://purl.obolibrary.org/obo/UBERON_0005760) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "septum urorectale" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) -### axillary artery `http://purl.obolibrary.org/obo/UBERON_0001394` + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Urorectal_septum" #### Added -- [axillary artery](http://purl.obolibrary.org/obo/UBERON_0001394) SubClassOf [connecting branch of](http://purl.obolibrary.org/obo/RO_0002252) some [axillary artery](http://purl.obolibrary.org/obo/UBERON_0001394) +- [urorectal septum](http://purl.obolibrary.org/obo/UBERON_0005760) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "septum urorectale" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Urorectal_septum" -### branch of external carotid artery `http://purl.obolibrary.org/obo/UBERON_0035398` -#### Removed -- [branch of external carotid artery](http://purl.obolibrary.org/obo/UBERON_0035398) EquivalentTo [artery](http://purl.obolibrary.org/obo/UBERON_0001637) and ([branching part of](http://purl.obolibrary.org/obo/RO_0002380) some [external carotid artery](http://purl.obolibrary.org/obo/UBERON_0001070)) - -- [branch of external carotid artery](http://purl.obolibrary.org/obo/UBERON_0035398) SubClassOf [systemic artery](http://purl.obolibrary.org/obo/UBERON_0004573) -- [branch of external carotid artery](http://purl.obolibrary.org/obo/UBERON_0035398) SubClassOf [branching part of](http://purl.obolibrary.org/obo/RO_0002380) some [external carotid artery](http://purl.obolibrary.org/obo/UBERON_0001070) +### urothelial cell `http://purl.obolibrary.org/obo/CL_0000731` #### Added -- [branch of external carotid artery](http://purl.obolibrary.org/obo/UBERON_0035398) EquivalentTo [artery](http://purl.obolibrary.org/obo/UBERON_0001637) and ([connecting branch of](http://purl.obolibrary.org/obo/RO_0002252) some [external carotid artery](http://purl.obolibrary.org/obo/UBERON_0001070)) +- [urothelial cell](http://purl.obolibrary.org/obo/CL_0000731) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) -- [branch of external carotid artery](http://purl.obolibrary.org/obo/UBERON_0035398) SubClassOf [connecting branch of](http://purl.obolibrary.org/obo/RO_0002252) some [external carotid artery](http://purl.obolibrary.org/obo/UBERON_0001070) -- [branch of external carotid artery](http://purl.obolibrary.org/obo/UBERON_0035398) SubClassOf [artery](http://purl.obolibrary.org/obo/UBERON_0001637) +### uterine cervix `http://purl.obolibrary.org/obo/UBERON_0000002` +#### Removed +- [uterine cervix](http://purl.obolibrary.org/obo/UBERON_0000002) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cervix uteri" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "EMAPA:29927" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) -### branch of internal carotid artery `http://purl.obolibrary.org/obo/UBERON_0035237` -#### Removed -- [branch of internal carotid artery](http://purl.obolibrary.org/obo/UBERON_0035237) EquivalentTo [carotid artery segment](http://purl.obolibrary.org/obo/UBERON_0005396) and ([branching part of](http://purl.obolibrary.org/obo/RO_0002380) some [internal carotid artery](http://purl.obolibrary.org/obo/UBERON_0001532)) +- [uterine cervix](http://purl.obolibrary.org/obo/UBERON_0000002) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "canalis cervicis uteri" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:17740" -- [branch of internal carotid artery](http://purl.obolibrary.org/obo/UBERON_0035237) SubClassOf [branching part of](http://purl.obolibrary.org/obo/RO_0002380) some [internal carotid artery](http://purl.obolibrary.org/obo/UBERON_0001532) + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) -- [branch of internal carotid artery](http://purl.obolibrary.org/obo/UBERON_0035237) SubClassOf [head blood vessel](http://purl.obolibrary.org/obo/UBERON_0003496) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" #### Added -- [branch of internal carotid artery](http://purl.obolibrary.org/obo/UBERON_0035237) EquivalentTo [carotid artery segment](http://purl.obolibrary.org/obo/UBERON_0005396) and ([connecting branch of](http://purl.obolibrary.org/obo/RO_0002252) some [internal carotid artery](http://purl.obolibrary.org/obo/UBERON_0001532)) +- [uterine cervix](http://purl.obolibrary.org/obo/UBERON_0000002) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "canalis cervicis uteri" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) -- [branch of internal carotid artery](http://purl.obolibrary.org/obo/UBERON_0035237) SubClassOf [connecting branch of](http://purl.obolibrary.org/obo/RO_0002252) some [internal carotid artery](http://purl.obolibrary.org/obo/UBERON_0001532) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:17740" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" -### bronchus `http://purl.obolibrary.org/obo/UBERON_0002185` -#### Removed -- [bronchus](http://purl.obolibrary.org/obo/UBERON_0002185) [depiction](http://xmlns.com/foaf/0.1/depiction) "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Lung.glb"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) +- [uterine cervix](http://purl.obolibrary.org/obo/UBERON_0000002) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "cervix uteri" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "EMAPA:29927" -- [bronchus](http://purl.obolibrary.org/obo/UBERON_0002185) [depiction](http://xmlns.com/foaf/0.1/depiction) "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Lung.glb"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) +### uterine resident macrophage `http://purl.obolibrary.org/obo/CL_4033064` -### caudal artery `http://purl.obolibrary.org/obo/UBERON_0003086` -#### Removed -- [caudal artery](http://purl.obolibrary.org/obo/UBERON_0003086) EquivalentTo [artery](http://purl.obolibrary.org/obo/UBERON_0001637) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [post-anal tail](http://purl.obolibrary.org/obo/UBERON_0007812)) and ([branching part of](http://purl.obolibrary.org/obo/RO_0002380) some [dorsal aorta](http://purl.obolibrary.org/obo/UBERON_0005805)) +#### Added +- [uterine resident macrophage](http://purl.obolibrary.org/obo/CL_4033064) [comment](http://www.w3.org/2000/01/rdf-schema#comment) "Uterine macrophages are reported to be evenly distributed throughout the endometrial stroma but with aggregations observed close to the lumen of superficial secretory glands." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:36113384" -- [caudal artery](http://purl.obolibrary.org/obo/UBERON_0003086) SubClassOf [branching part of](http://purl.obolibrary.org/obo/RO_0002380) some [dorsal aorta](http://purl.obolibrary.org/obo/UBERON_0005805) +- [uterine resident macrophage](http://purl.obolibrary.org/obo/CL_4033064) [has_broad_synonym](http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym) "uterine macrophage" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:36113384" -- [caudal artery](http://purl.obolibrary.org/obo/UBERON_0003086) SubClassOf [trunk blood vessel](http://purl.obolibrary.org/obo/UBERON_0003513) +- [uterine resident macrophage](http://purl.obolibrary.org/obo/CL_4033064) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A tissue-resident macrophage that is part of the uterus." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:36113384" -- [caudal artery](http://purl.obolibrary.org/obo/UBERON_0003086) SubClassOf [systemic artery](http://purl.obolibrary.org/obo/UBERON_0004573) +- [uterine resident macrophage](http://purl.obolibrary.org/obo/CL_4033064) [label](http://www.w3.org/2000/01/rdf-schema#label) "uterine resident macrophage" -#### Added -- [caudal artery](http://purl.obolibrary.org/obo/UBERON_0003086) EquivalentTo [artery](http://purl.obolibrary.org/obo/UBERON_0001637) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [post-anal tail](http://purl.obolibrary.org/obo/UBERON_0007812)) and ([connecting branch of](http://purl.obolibrary.org/obo/RO_0002252) some [dorsal aorta](http://purl.obolibrary.org/obo/UBERON_0005805)) +- [uterine resident macrophage](http://purl.obolibrary.org/obo/CL_4033064) [date](http://purl.org/dc/terms/date) "2024-01-08T16:05:09Z"^^[dateTime](http://www.w3.org/2001/XMLSchema#dateTime) -- [caudal artery](http://purl.obolibrary.org/obo/UBERON_0003086) SubClassOf [artery](http://purl.obolibrary.org/obo/UBERON_0001637) +- [uterine resident macrophage](http://purl.obolibrary.org/obo/CL_4033064) [contributor](http://purl.org/dc/terms/contributor) [0000-0001-6677-8489](https://orcid.org/0000-0001-6677-8489) -- [caudal artery](http://purl.obolibrary.org/obo/UBERON_0003086) SubClassOf [connecting branch of](http://purl.obolibrary.org/obo/RO_0002252) some [dorsal aorta](http://purl.obolibrary.org/obo/UBERON_0005805) +- Class: [uterine resident macrophage](http://purl.obolibrary.org/obo/CL_4033064) +- [uterine resident macrophage](http://purl.obolibrary.org/obo/CL_4033064) EquivalentTo [tissue-resident macrophage](http://purl.obolibrary.org/obo/CL_0000864) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [uterus](http://purl.obolibrary.org/obo/UBERON_0000995)) -### cavernous artery `http://purl.obolibrary.org/obo/UBERON_0000457` -#### Removed -- [cavernous artery](http://purl.obolibrary.org/obo/UBERON_0000457) EquivalentTo [artery](http://purl.obolibrary.org/obo/UBERON_0001637) and ([supplies](http://purl.obolibrary.org/obo/RO_0002178) some [trigeminal ganglion](http://purl.obolibrary.org/obo/UBERON_0001675)) and ([branching part of](http://purl.obolibrary.org/obo/RO_0002380) some [internal carotid artery](http://purl.obolibrary.org/obo/UBERON_0001532)) +- [uterine resident macrophage](http://purl.obolibrary.org/obo/CL_4033064) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [uterus](http://purl.obolibrary.org/obo/UBERON_0000995) -- [cavernous artery](http://purl.obolibrary.org/obo/UBERON_0000457) SubClassOf [branching part of](http://purl.obolibrary.org/obo/RO_0002380) some [internal carotid artery](http://purl.obolibrary.org/obo/UBERON_0001532) +- [uterine resident macrophage](http://purl.obolibrary.org/obo/CL_4033064) SubClassOf [tissue-resident macrophage](http://purl.obolibrary.org/obo/CL_0000864) -- [cavernous artery](http://purl.obolibrary.org/obo/UBERON_0000457) SubClassOf [systemic artery](http://purl.obolibrary.org/obo/UBERON_0004573) -- [cavernous artery](http://purl.obolibrary.org/obo/UBERON_0000457) SubClassOf [head blood vessel](http://purl.obolibrary.org/obo/UBERON_0003496) +### uterine smooth muscle cell `http://purl.obolibrary.org/obo/CL_0002601` #### Added -- [cavernous artery](http://purl.obolibrary.org/obo/UBERON_0000457) EquivalentTo [artery](http://purl.obolibrary.org/obo/UBERON_0001637) and ([supplies](http://purl.obolibrary.org/obo/RO_0002178) some [trigeminal ganglion](http://purl.obolibrary.org/obo/UBERON_0001675)) and ([connecting branch of](http://purl.obolibrary.org/obo/RO_0002252) some [internal carotid artery](http://purl.obolibrary.org/obo/UBERON_0001532)) +- [uterine smooth muscle cell](http://purl.obolibrary.org/obo/CL_0002601) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) -- [cavernous artery](http://purl.obolibrary.org/obo/UBERON_0000457) SubClassOf [connecting branch of](http://purl.obolibrary.org/obo/RO_0002252) some [internal carotid artery](http://purl.obolibrary.org/obo/UBERON_0001532) -- [cavernous artery](http://purl.obolibrary.org/obo/UBERON_0000457) SubClassOf [artery](http://purl.obolibrary.org/obo/UBERON_0001637) +### uterine tube infundibulum `http://purl.obolibrary.org/obo/UBERON_0003984` +#### Removed +- [uterine tube infundibulum](http://purl.obolibrary.org/obo/UBERON_0003984) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "infundibulum tubae uterinae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Infundibulum_of_uterine_tube" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) -### cervical rib `http://purl.obolibrary.org/obo/UBERON_0018144` -#### Removed -- [cervical rib](http://purl.obolibrary.org/obo/UBERON_0018144) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UBERONTEMP:d522e981-3a43-4cab-9862-4344b5c3ff22" +#### Added +- [uterine tube infundibulum](http://purl.obolibrary.org/obo/UBERON_0003984) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "infundibulum tubae uterinae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Infundibulum_of_uterine_tube" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) -### chorionic plate blood vessel `http://purl.obolibrary.org/obo/UBERON_8600021` +### uterus or analog `http://purl.obolibrary.org/obo/UBERON_0006834` #### Added -- [chorionic plate blood vessel](http://purl.obolibrary.org/obo/UBERON_8600021) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606) +- [uterus or analog](http://purl.obolibrary.org/obo/UBERON_0006834) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00004924" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) -- [chorionic plate blood vessel](http://purl.obolibrary.org/obo/UBERON_8600021) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [human_reference_atlas](http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas) - -### ciliary processes `http://purl.obolibrary.org/obo/UBERON_0010427` +### uvea `http://purl.obolibrary.org/obo/UBERON_0001768` #### Removed -- [ciliary processes](http://purl.obolibrary.org/obo/UBERON_0010427) [depiction](http://xmlns.com/foaf/0.1/depiction) "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Eye_L.glb"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) +- [uvea](http://purl.obolibrary.org/obo/UBERON_0001768) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tunica vasculosa bulbi" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Uvea" -- [ciliary processes](http://purl.obolibrary.org/obo/UBERON_0010427) [depiction](http://xmlns.com/foaf/0.1/depiction) "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Eye_L.glb"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) -- [ciliary processes](http://purl.obolibrary.org/obo/UBERON_0010427) [depiction](http://xmlns.com/foaf/0.1/depiction) "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Eye_R.glb"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) - -- [ciliary processes](http://purl.obolibrary.org/obo/UBERON_0010427) [depiction](http://xmlns.com/foaf/0.1/depiction) "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Eye_R.glb"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) +#### Added +- [uvea](http://purl.obolibrary.org/obo/UBERON_0001768) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "tunica vasculosa bulbi" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Uvea" -### committed double negative thymocyte (Homo sapiens) `http://purl.obolibrary.org/obo/CL_0009082` +### vaginal fluid `http://purl.obolibrary.org/obo/UBERON_0036243` +#### Removed +- [vaginal fluid](http://purl.obolibrary.org/obo/UBERON_0036243) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0003084" + - [contributor](http://purl.org/dc/terms/contributor) "https://orcid.org/0000-0003-4423-4370" #### Added -- [committed double negative thymocyte (Homo sapiens)](http://purl.obolibrary.org/obo/CL_0009082) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [human_reference_atlas](http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas) +- [vaginal fluid](http://purl.obolibrary.org/obo/UBERON_0036243) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0003084" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" -### common hepatic artery `http://purl.obolibrary.org/obo/UBERON_0005436` + - [author_id](https://w3id.org/sssom/author_id) [0000-0003-4423-4370](https://orcid.org/0000-0003-4423-4370) + + +### vaginal venous plexus `http://purl.obolibrary.org/obo/UBERON_0001472` #### Removed -- [common hepatic artery](http://purl.obolibrary.org/obo/UBERON_0005436) SubClassOf [branching part of](http://purl.obolibrary.org/obo/RO_0002380) some [celiac artery](http://purl.obolibrary.org/obo/UBERON_0001640) +- [vaginal venous plexus](http://purl.obolibrary.org/obo/UBERON_0001472) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "plexus venosus vaginalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Vaginal_venous_plexus" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) #### Added -- [common hepatic artery](http://purl.obolibrary.org/obo/UBERON_0005436) SubClassOf [connecting branch of](http://purl.obolibrary.org/obo/RO_0002252) some [celiac artery](http://purl.obolibrary.org/obo/UBERON_0001640) +- [vaginal venous plexus](http://purl.obolibrary.org/obo/UBERON_0001472) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "plexus venosus vaginalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Vaginal_venous_plexus" -### common_name `http://purl.obolibrary.org/obo/ncbitaxon#common_name` +### vagus nerve `http://purl.obolibrary.org/obo/UBERON_0001759` #### Removed -- AnnotationProperty: [common_name](http://purl.obolibrary.org/obo/ncbitaxon#common_name) +- [vagus nerve](http://purl.obolibrary.org/obo/UBERON_0001759) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nervus vagus [x]" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:5731" -- [common_name](http://purl.obolibrary.org/obo/ncbitaxon#common_name) SubPropertyOf: [synonym_type_property](http://www.geneontology.org/formats/oboInOwl#SynonymTypeProperty) + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" +- [vagus nerve](http://purl.obolibrary.org/obo/UBERON_0001759) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nervus vagus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Vagus_nerve" -### connecting branch of `http://purl.obolibrary.org/obo/RO_0002252` + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0003472" #### Added -- [connecting branch of](http://purl.obolibrary.org/obo/RO_0002252) [RO_0004036](http://purl.obolibrary.org/obo/RO_0004036) [part_of](http://purl.obolibrary.org/obo/BFO_0000050) +- [vagus nerve](http://purl.obolibrary.org/obo/UBERON_0001759) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nervus vagus [x]" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) -- [connecting branch of](http://purl.obolibrary.org/obo/RO_0002252) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "b connecting-branch-of s iff b is connected to s, and there exists some tree-like structure t such that the mereological sum of b plus s is either the same as t or a branching-part-of t." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:5731" -- [connecting branch of](http://purl.obolibrary.org/obo/RO_0002252) [see also](http://www.w3.org/2000/01/rdf-schema#seeAlso) [2212](https://github.com/obophenotype/uberon/issues/2212) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" -- [connecting branch of](http://purl.obolibrary.org/obo/RO_0002252) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "uberon" +- [vagus nerve](http://purl.obolibrary.org/obo/UBERON_0001759) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nervus vagus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) -- [connecting branch of](http://purl.obolibrary.org/obo/RO_0002252) [IAO_0000112](http://purl.obolibrary.org/obo/IAO_0000112) "In the tree T depicted in https://oborel.github.io/obo-relations/branching_part_of.png, B1 is connecting branch of S, and B1-1 as a connecting branch of B1." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Vagus_nerve" -- [connecting branch of](http://purl.obolibrary.org/obo/RO_0002252) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "RO:0002252" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0003472" -- [connecting branch of](http://purl.obolibrary.org/obo/RO_0002252) [label](http://www.w3.org/2000/01/rdf-schema#label) "connecting branch of" -- [connecting branch of](http://purl.obolibrary.org/obo/RO_0002252) [shorthand](http://www.geneontology.org/formats/oboInOwl#shorthand) "connecting_branch_of" +### vasa recta `http://purl.obolibrary.org/obo/UBERON_0004726` +#### Removed +- [vasa recta](http://purl.obolibrary.org/obo/UBERON_0004726) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "vasa recta renis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:72006" -- [connecting branch of](http://purl.obolibrary.org/obo/RO_0002252) [id](http://www.geneontology.org/formats/oboInOwl#id) "connecting_branch_of" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) -- ObjectProperty: [connecting branch of](http://purl.obolibrary.org/obo/RO_0002252) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" -- [connecting branch of](http://purl.obolibrary.org/obo/RO_0002252) InverseOf [has connecting branch](http://purl.obolibrary.org/obo/RO_0002253) +- [vasa recta](http://purl.obolibrary.org/obo/UBERON_0004726) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "arteriolae rectae renis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:72006" -- [connecting branch of](http://purl.obolibrary.org/obo/RO_0002252) SubPropertyOf: [connected to](http://purl.obolibrary.org/obo/RO_0002170) + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) -- [connecting branch of](http://purl.obolibrary.org/obo/RO_0002252) SubPropertyOf: [in branching relationship with](http://purl.obolibrary.org/obo/RO_0002375) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" +- [vasa recta](http://purl.obolibrary.org/obo/UBERON_0004726) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteriolae rectae renis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Vasa_recta" -### corpus luteum `http://purl.obolibrary.org/obo/UBERON_0002512` -#### Removed -- [corpus luteum](http://purl.obolibrary.org/obo/UBERON_0002512) SubClassOf [only in taxon](http://purl.obolibrary.org/obo/RO_0002160) some [Mammalia](http://purl.obolibrary.org/obo/NCBITaxon_40674) - - [source](http://www.geneontology.org/formats/oboInOwl#source) "Wikipedia" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) #### Added -- [corpus luteum](http://purl.obolibrary.org/obo/UBERON_0002512) SubClassOf [only in taxon](http://purl.obolibrary.org/obo/RO_0002160) some [Vertebrata ](http://purl.obolibrary.org/obo/NCBITaxon_7742) +- [vasa recta](http://purl.obolibrary.org/obo/UBERON_0004726) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "arteriolae rectae renis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:72006" -### cranial bone `http://purl.obolibrary.org/obo/UBERON_0004766` -#### Removed -- [cranial bone](http://purl.obolibrary.org/obo/UBERON_0004766) SubClassOf [head bone](http://purl.obolibrary.org/obo/UBERON_0003457) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" -#### Added -- [cranial bone](http://purl.obolibrary.org/obo/UBERON_0004766) SubClassOf [bone element](http://purl.obolibrary.org/obo/UBERON_0001474) +- [vasa recta](http://purl.obolibrary.org/obo/UBERON_0004726) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "vasa recta renis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:72006" -### cranial suture `http://purl.obolibrary.org/obo/UBERON_0003685` -#### Removed -- [cranial suture](http://purl.obolibrary.org/obo/UBERON_0003685) SubClassOf [developmentally induced by](http://purl.obolibrary.org/obo/RO_0002256) some [dura mater](http://purl.obolibrary.org/obo/UBERON_0002363) - - [source](http://www.geneontology.org/formats/oboInOwl#source) "PMID:16496288" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" +- [vasa recta](http://purl.obolibrary.org/obo/UBERON_0004726) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "arteriolae rectae renis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Vasa_recta" -### cranium `http://purl.obolibrary.org/obo/UBERON_0003128` -#### Removed -- [cranium](http://purl.obolibrary.org/obo/UBERON_0003128) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [skull](http://purl.obolibrary.org/obo/UBERON_0003129) + +### vasa recta ascending limb cell `http://purl.obolibrary.org/obo/CL_1001131` #### Added -- [cranium](http://purl.obolibrary.org/obo/UBERON_0003128) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [NCBITaxon_7762](http://purl.obolibrary.org/obo/NCBITaxon_7762) +- [vasa recta ascending limb cell](http://purl.obolibrary.org/obo/CL_1001131) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) -### deep auricular artery `http://purl.obolibrary.org/obo/UBERON_0014695` -#### Removed -- [deep auricular artery](http://purl.obolibrary.org/obo/UBERON_0014695) SubClassOf [branching part of](http://purl.obolibrary.org/obo/RO_0002380) some [maxillary artery](http://purl.obolibrary.org/obo/UBERON_0001616) - - [source](http://www.geneontology.org/formats/oboInOwl#source) "FMA" +### vasa recta descending limb cell `http://purl.obolibrary.org/obo/CL_1001285` #### Added -- [deep auricular artery](http://purl.obolibrary.org/obo/UBERON_0014695) SubClassOf [connecting branch of](http://purl.obolibrary.org/obo/RO_0002252) some [maxillary artery](http://purl.obolibrary.org/obo/UBERON_0001616) - - [source](http://www.geneontology.org/formats/oboInOwl#source) "FMA" +- [vasa recta descending limb cell](http://purl.obolibrary.org/obo/CL_1001285) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) -### deep cervical artery `http://purl.obolibrary.org/obo/UBERON_0012321` -#### Removed -- [deep cervical artery](http://purl.obolibrary.org/obo/UBERON_0012321) SubClassOf [branching part of](http://purl.obolibrary.org/obo/RO_0002380) some [costo-cervical trunk](http://purl.obolibrary.org/obo/UBERON_0004688) - - [source](http://www.geneontology.org/formats/oboInOwl#source) "FMA" +### vascular associated smooth muscle cell `http://purl.obolibrary.org/obo/CL_0000359` #### Added -- [deep cervical artery](http://purl.obolibrary.org/obo/UBERON_0012321) SubClassOf [connecting branch of](http://purl.obolibrary.org/obo/RO_0002252) some [costo-cervical trunk](http://purl.obolibrary.org/obo/UBERON_0004688) - - [source](http://www.geneontology.org/formats/oboInOwl#source) "FMA" - - -### deep femoral artery `http://purl.obolibrary.org/obo/UBERON_0001355` -#### Removed -- [deep femoral artery](http://purl.obolibrary.org/obo/UBERON_0001355) EquivalentTo [artery](http://purl.obolibrary.org/obo/UBERON_0001637) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [deep vasculature](http://purl.obolibrary.org/obo/UBERON_0035551)) and ([branching part of](http://purl.obolibrary.org/obo/RO_0002380) some [femoral artery](http://purl.obolibrary.org/obo/UBERON_0002060)) +- [vascular associated smooth muscle cell](http://purl.obolibrary.org/obo/CL_0000359) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) -- [deep femoral artery](http://purl.obolibrary.org/obo/UBERON_0001355) SubClassOf [branching part of](http://purl.obolibrary.org/obo/RO_0002380) some [femoral artery](http://purl.obolibrary.org/obo/UBERON_0002060) -- [deep femoral artery](http://purl.obolibrary.org/obo/UBERON_0001355) SubClassOf [systemic artery](http://purl.obolibrary.org/obo/UBERON_0004573) +### vascular leptomeningeal cell `http://purl.obolibrary.org/obo/CL_4023051` #### Added -- [deep femoral artery](http://purl.obolibrary.org/obo/UBERON_0001355) EquivalentTo [artery](http://purl.obolibrary.org/obo/UBERON_0001637) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [deep vasculature](http://purl.obolibrary.org/obo/UBERON_0035551)) and ([connecting branch of](http://purl.obolibrary.org/obo/RO_0002252) some [femoral artery](http://purl.obolibrary.org/obo/UBERON_0002060)) - -- [deep femoral artery](http://purl.obolibrary.org/obo/UBERON_0001355) SubClassOf [connecting branch of](http://purl.obolibrary.org/obo/RO_0002252) some [femoral artery](http://purl.obolibrary.org/obo/UBERON_0002060) +- [vascular leptomeningeal cell](http://purl.obolibrary.org/obo/CL_4023051) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) -- [deep femoral artery](http://purl.obolibrary.org/obo/UBERON_0001355) SubClassOf [artery](http://purl.obolibrary.org/obo/UBERON_0001637) +### vascular leptomeningeal cell (Mmus) `http://purl.obolibrary.org/obo/CL_4023056` -### deferent duct artery `http://purl.obolibrary.org/obo/UBERON_0005192` -#### Removed -- [deferent duct artery](http://purl.obolibrary.org/obo/UBERON_0005192) SubClassOf [systemic artery](http://purl.obolibrary.org/obo/UBERON_0004573) +#### Added +- [vascular leptomeningeal cell (Mmus)](http://purl.obolibrary.org/obo/CL_4023056) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) -- [deferent duct artery](http://purl.obolibrary.org/obo/UBERON_0005192) SubClassOf [branching part of](http://purl.obolibrary.org/obo/RO_0002380) some [superior vesical artery](http://purl.obolibrary.org/obo/UBERON_0001312) - - [source](http://www.geneontology.org/formats/oboInOwl#source) "Wikipedia" -- [deferent duct artery](http://purl.obolibrary.org/obo/UBERON_0005192) SubClassOf [branching part of](http://purl.obolibrary.org/obo/RO_0002380) some [umbilical artery](http://purl.obolibrary.org/obo/UBERON_0001310) - - [source](http://www.geneontology.org/formats/oboInOwl#source) "FMA" +### vascular lymphangioblast `http://purl.obolibrary.org/obo/CL_0005022` #### Added -- [deferent duct artery](http://purl.obolibrary.org/obo/UBERON_0005192) SubClassOf [artery](http://purl.obolibrary.org/obo/UBERON_0001637) - -- [deferent duct artery](http://purl.obolibrary.org/obo/UBERON_0005192) SubClassOf [connecting branch of](http://purl.obolibrary.org/obo/RO_0002252) some [superior vesical artery](http://purl.obolibrary.org/obo/UBERON_0001312) - - [source](http://www.geneontology.org/formats/oboInOwl#source) "Wikipedia" +- [vascular lymphangioblast](http://purl.obolibrary.org/obo/CL_0005022) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) -### dermatocranium `http://purl.obolibrary.org/obo/UBERON_0003113` +### vascular plexus `http://purl.obolibrary.org/obo/UBERON_0005629` #### Removed -- [dermatocranium](http://purl.obolibrary.org/obo/UBERON_0003113) SubClassOf [only in taxon](http://purl.obolibrary.org/obo/RO_0002160) some [Gnathostomata ](http://purl.obolibrary.org/obo/NCBITaxon_7776) +- [vascular plexus](http://purl.obolibrary.org/obo/UBERON_0005629) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "plexus vasculosus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) #### Added -- [dermatocranium](http://purl.obolibrary.org/obo/UBERON_0003113) SubClassOf [only in taxon](http://purl.obolibrary.org/obo/RO_0002160) some [Vertebrata ](http://purl.obolibrary.org/obo/NCBITaxon_7742) +- [vascular plexus](http://purl.obolibrary.org/obo/UBERON_0005629) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "plexus vasculosus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) -### digestive tract epithelium `http://purl.obolibrary.org/obo/UBERON_0003929` +### vasculature of retina `http://purl.obolibrary.org/obo/UBERON_0004864` #### Removed -- [digestive tract epithelium](http://purl.obolibrary.org/obo/UBERON_0003929) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FBbt:00047143" - +- [vasculature of retina](http://purl.obolibrary.org/obo/UBERON_0004864) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "vasa sanguinea retinae" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:76552" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) -### endothelial cell of central vein of liver `http://purl.obolibrary.org/obo/CL_4033061` + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" #### Added -- [endothelial cell of central vein of liver](http://purl.obolibrary.org/obo/CL_4033061) [has_broad_synonym](http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym) "endothelial cell of central vein" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:28287163" +- [vasculature of retina](http://purl.obolibrary.org/obo/UBERON_0004864) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "vasa sanguinea retinae" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) -- [endothelial cell of central vein of liver](http://purl.obolibrary.org/obo/CL_4033061) [contributor](http://purl.org/dc/terms/contributor) [0000-0001-6677-8489](https://orcid.org/0000-0001-6677-8489) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:76552" -- [endothelial cell of central vein of liver](http://purl.obolibrary.org/obo/CL_4033061) [label](http://www.w3.org/2000/01/rdf-schema#label) "endothelial cell of central vein of liver" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" -- [endothelial cell of central vein of liver](http://purl.obolibrary.org/obo/CL_4033061) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "An endothelial cell that is part of a central vein of liver." - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:28287163" -- Class: [endothelial cell of central vein of liver](http://purl.obolibrary.org/obo/CL_4033061) +### vein `http://purl.obolibrary.org/obo/UBERON_0001638` +#### Removed +- [vein](http://purl.obolibrary.org/obo/UBERON_0001638) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vena" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Vein" -- [endothelial cell of central vein of liver](http://purl.obolibrary.org/obo/CL_4033061) EquivalentTo [endothelial cell](http://purl.obolibrary.org/obo/CL_0000115) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [central vein of liver](http://purl.obolibrary.org/obo/UBERON_0006841)) + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) -- [endothelial cell of central vein of liver](http://purl.obolibrary.org/obo/CL_4033061) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [central vein of liver](http://purl.obolibrary.org/obo/UBERON_0006841) +#### Added +- [vein](http://purl.obolibrary.org/obo/UBERON_0001638) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vena" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Vein" -- [endothelial cell of central vein of liver](http://purl.obolibrary.org/obo/CL_4033061) SubClassOf [endothelial cell](http://purl.obolibrary.org/obo/CL_0000115) + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) -### epithelium `http://purl.obolibrary.org/obo/UBERON_0000483` -#### Removed -- [epithelium](http://purl.obolibrary.org/obo/UBERON_0000483) SubClassOf [only in taxon](http://purl.obolibrary.org/obo/RO_0002160) some [Eumetazoa](http://purl.obolibrary.org/obo/NCBITaxon_6072) +### vein endothelial cell `http://purl.obolibrary.org/obo/CL_0002543` #### Added -- [epithelium](http://purl.obolibrary.org/obo/UBERON_0000483) SubClassOf [only in taxon](http://purl.obolibrary.org/obo/RO_0002160) some [Metazoa](http://purl.obolibrary.org/obo/NCBITaxon_33208) - - [source](http://www.geneontology.org/formats/oboInOwl#source) "http://palaeos.com/metazoa/porifera/homoscleromorpha.html" +- [vein endothelial cell](http://purl.obolibrary.org/obo/CL_0002543) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) -### extraembryonic portion of umbilical artery `http://purl.obolibrary.org/obo/UBERON_0011693` +### vein of lip `http://purl.obolibrary.org/obo/UBERON_0013136` #### Removed -- [extraembryonic portion of umbilical artery](http://purl.obolibrary.org/obo/UBERON_0011693) SubClassOf [branching part of](http://purl.obolibrary.org/obo/RO_0002380) some [internal iliac artery](http://purl.obolibrary.org/obo/UBERON_0001309) - - [source](http://www.geneontology.org/formats/oboInOwl#source) "FMA" - -- [extraembryonic portion of umbilical artery](http://purl.obolibrary.org/obo/UBERON_0011693) SubClassOf [systemic artery](http://purl.obolibrary.org/obo/UBERON_0004573) +- [vein of lip](http://purl.obolibrary.org/obo/UBERON_0013136) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "vena labialis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) #### Added -- [extraembryonic portion of umbilical artery](http://purl.obolibrary.org/obo/UBERON_0011693) SubClassOf [artery](http://purl.obolibrary.org/obo/UBERON_0001637) - -- [extraembryonic portion of umbilical artery](http://purl.obolibrary.org/obo/UBERON_0011693) SubClassOf [connecting branch of](http://purl.obolibrary.org/obo/RO_0002252) some [internal iliac artery](http://purl.obolibrary.org/obo/UBERON_0001309) - - [source](http://www.geneontology.org/formats/oboInOwl#source) "FMA" +- [vein of lip](http://purl.obolibrary.org/obo/UBERON_0013136) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "vena labialis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) -### eye trabecular meshwork `http://purl.obolibrary.org/obo/UBERON_0005969` +### vein of lower lip `http://purl.obolibrary.org/obo/UBERON_0003478` #### Removed -- [eye trabecular meshwork](http://purl.obolibrary.org/obo/UBERON_0005969) [depiction](http://xmlns.com/foaf/0.1/depiction) "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Eye_L.glb"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) +- [vein of lower lip](http://purl.obolibrary.org/obo/UBERON_0003478) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "venae labiales inferiores" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Inferior_labial_vein" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) -- [eye trabecular meshwork](http://purl.obolibrary.org/obo/UBERON_0005969) [depiction](http://xmlns.com/foaf/0.1/depiction) "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Eye_L.glb"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) +- [vein of lower lip](http://purl.obolibrary.org/obo/UBERON_0003478) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "vena labialis inferior" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) -- [eye trabecular meshwork](http://purl.obolibrary.org/obo/UBERON_0005969) [depiction](http://xmlns.com/foaf/0.1/depiction) "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Eye_R.glb"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) +#### Added +- [vein of lower lip](http://purl.obolibrary.org/obo/UBERON_0003478) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "vena labialis inferior" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) -- [eye trabecular meshwork](http://purl.obolibrary.org/obo/UBERON_0005969) [depiction](http://xmlns.com/foaf/0.1/depiction) "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Eye_R.glb"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) +- [vein of lower lip](http://purl.obolibrary.org/obo/UBERON_0003478) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "venae labiales inferiores" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Inferior_labial_vein" -### facial artery `http://purl.obolibrary.org/obo/UBERON_0001612` +### vein of upper lip `http://purl.obolibrary.org/obo/UBERON_0003477` #### Removed -- [facial artery](http://purl.obolibrary.org/obo/UBERON_0001612) EquivalentTo [artery](http://purl.obolibrary.org/obo/UBERON_0001637) and ([supplies](http://purl.obolibrary.org/obo/RO_0002178) some [face](http://purl.obolibrary.org/obo/UBERON_0001456)) and ([branching part of](http://purl.obolibrary.org/obo/RO_0002380) some [external carotid artery](http://purl.obolibrary.org/obo/UBERON_0001070)) +- [vein of upper lip](http://purl.obolibrary.org/obo/UBERON_0003477) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "vena labialis superior" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) #### Added -- [facial artery](http://purl.obolibrary.org/obo/UBERON_0001612) EquivalentTo [artery](http://purl.obolibrary.org/obo/UBERON_0001637) and ([supplies](http://purl.obolibrary.org/obo/RO_0002178) some [face](http://purl.obolibrary.org/obo/UBERON_0001456)) and ([connecting branch of](http://purl.obolibrary.org/obo/RO_0002252) some [external carotid artery](http://purl.obolibrary.org/obo/UBERON_0001070)) +- [vein of upper lip](http://purl.obolibrary.org/obo/UBERON_0003477) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "vena labialis superior" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) -### femoral artery `http://purl.obolibrary.org/obo/UBERON_0002060` +### venous blood `http://purl.obolibrary.org/obo/UBERON_0013756` #### Removed -- [femoral artery](http://purl.obolibrary.org/obo/UBERON_0002060) SubClassOf [branching part of](http://purl.obolibrary.org/obo/RO_0002380) some [external iliac artery](http://purl.obolibrary.org/obo/UBERON_0001308) - - [source](http://www.geneontology.org/formats/oboInOwl#source) "FMA" - - - [source](http://www.geneontology.org/formats/oboInOwl#source) "WP" - -- [femoral artery](http://purl.obolibrary.org/obo/UBERON_0002060) SubClassOf [systemic artery](http://purl.obolibrary.org/obo/UBERON_0004573) +- [venous blood](http://purl.obolibrary.org/obo/UBERON_0013756) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0006187" + - [contributor](http://purl.org/dc/terms/contributor) "https://orcid.org/0000-0003-4423-4370" #### Added -- [femoral artery](http://purl.obolibrary.org/obo/UBERON_0002060) SubClassOf [connecting branch of](http://purl.obolibrary.org/obo/RO_0002252) some [external iliac artery](http://purl.obolibrary.org/obo/UBERON_0001308) - - [source](http://www.geneontology.org/formats/oboInOwl#source) "FMA" +- [venous blood](http://purl.obolibrary.org/obo/UBERON_0013756) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0006187" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) - - [source](http://www.geneontology.org/formats/oboInOwl#source) "WP" + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" -- [femoral artery](http://purl.obolibrary.org/obo/UBERON_0002060) SubClassOf [artery](http://purl.obolibrary.org/obo/UBERON_0001637) + - [author_id](https://w3id.org/sssom/author_id) [0000-0003-4423-4370](https://orcid.org/0000-0003-4423-4370) -### foramen for glossopharyngeal nerve `http://purl.obolibrary.org/obo/UBERON_0018321` +### venous dural sinus `http://purl.obolibrary.org/obo/UBERON_0005486` #### Removed -- [foramen for glossopharyngeal nerve](http://purl.obolibrary.org/obo/UBERON_0018321) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UBERONTEMP:9ca0bda7-9111-4f59-bc72-5d47bc3d7d61" +- [venous dural sinus](http://purl.obolibrary.org/obo/UBERON_0005486) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "s. durae matris" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Dural_venous_sinuses" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) +#### Added +- [venous dural sinus](http://purl.obolibrary.org/obo/UBERON_0005486) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "s. durae matris" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Dural_venous_sinuses" -### glial cell `http://purl.obolibrary.org/obo/CL_0000125` + +### venous plexus `http://purl.obolibrary.org/obo/UBERON_0001593` #### Removed -- [glial cell](http://purl.obolibrary.org/obo/CL_0000125) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [human_reference_atlas](http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas) +- [venous plexus](http://purl.obolibrary.org/obo/UBERON_0001593) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "plexus venosus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) -- [glial cell](http://purl.obolibrary.org/obo/CL_0000125) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Venous_plexus" +- [venous plexus](http://purl.obolibrary.org/obo/UBERON_0001593) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "rete venosum" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Venous_plexus" -### haploid cell `http://purl.obolibrary.org/obo/CL_0000413` -#### Removed -- [haploid cell](http://purl.obolibrary.org/obo/CL_0000413) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606) +#### Added +- [venous plexus](http://purl.obolibrary.org/obo/UBERON_0001593) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "plexus venosus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Venous_plexus" -- [haploid cell](http://purl.obolibrary.org/obo/CL_0000413) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [human_reference_atlas](http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas) +- [venous plexus](http://purl.obolibrary.org/obo/UBERON_0001593) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "rete venosum" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Venous_plexus" -### has connecting branch `http://purl.obolibrary.org/obo/RO_0002253` +### venous valve `http://purl.obolibrary.org/obo/UBERON_0006675` +#### Removed +- [venous valve](http://purl.obolibrary.org/obo/UBERON_0006675) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D055422" #### Added -- [has connecting branch](http://purl.obolibrary.org/obo/RO_0002253) [label](http://www.w3.org/2000/01/rdf-schema#label) "has connecting branch" +- [venous valve](http://purl.obolibrary.org/obo/UBERON_0006675) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D055422" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) -- [has connecting branch](http://purl.obolibrary.org/obo/RO_0002253) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [RO_0002259](http://purl.obolibrary.org/obo/RO_0002259) + - [author_id](https://w3id.org/sssom/author_id) [0000-0001-9439-5346](https://orcid.org/0000-0001-9439-5346) -- [has connecting branch](http://purl.obolibrary.org/obo/RO_0002253) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "inverse of connecting branch of" + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" -- [has connecting branch](http://purl.obolibrary.org/obo/RO_0002253) [RO_0004036](http://purl.obolibrary.org/obo/RO_0004036) [has part](http://purl.obolibrary.org/obo/BFO_0000051) -- ObjectProperty: [has connecting branch](http://purl.obolibrary.org/obo/RO_0002253) +### ventral cochlear nucleus `http://purl.obolibrary.org/obo/UBERON_0002828` +#### Removed +- [ventral cochlear nucleus](http://purl.obolibrary.org/obo/UBERON_0002828) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus acustici accessorici" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:722" -- [has connecting branch](http://purl.obolibrary.org/obo/RO_0002253) SubPropertyOf: [in branching relationship with](http://purl.obolibrary.org/obo/RO_0002375) + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) +- [ventral cochlear nucleus](http://purl.obolibrary.org/obo/UBERON_0002828) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus cochlearis anterior" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:722" -### ileocolic artery `http://purl.obolibrary.org/obo/UBERON_0001197` -#### Removed -- [ileocolic artery](http://purl.obolibrary.org/obo/UBERON_0001197) EquivalentTo [artery](http://purl.obolibrary.org/obo/UBERON_0001637) and ([supplies](http://purl.obolibrary.org/obo/RO_0002178) some [caecum](http://purl.obolibrary.org/obo/UBERON_0001153)) and ([supplies](http://purl.obolibrary.org/obo/RO_0002178) some [vermiform appendix](http://purl.obolibrary.org/obo/UBERON_0001154)) and ([supplies](http://purl.obolibrary.org/obo/RO_0002178) some [ileum](http://purl.obolibrary.org/obo/UBERON_0002116)) and ([branching part of](http://purl.obolibrary.org/obo/RO_0002380) some [superior mesenteric artery](http://purl.obolibrary.org/obo/UBERON_0001182)) + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) -- [ileocolic artery](http://purl.obolibrary.org/obo/UBERON_0001197) SubClassOf [systemic artery](http://purl.obolibrary.org/obo/UBERON_0004573) +- [ventral cochlear nucleus](http://purl.obolibrary.org/obo/UBERON_0002828) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus cochlearis ventralis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:722" -- [ileocolic artery](http://purl.obolibrary.org/obo/UBERON_0001197) SubClassOf [branching part of](http://purl.obolibrary.org/obo/RO_0002380) some [superior mesenteric artery](http://purl.obolibrary.org/obo/UBERON_0001182) + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) #### Added -- [ileocolic artery](http://purl.obolibrary.org/obo/UBERON_0001197) EquivalentTo [artery](http://purl.obolibrary.org/obo/UBERON_0001637) and ([supplies](http://purl.obolibrary.org/obo/RO_0002178) some [caecum](http://purl.obolibrary.org/obo/UBERON_0001153)) and ([supplies](http://purl.obolibrary.org/obo/RO_0002178) some [vermiform appendix](http://purl.obolibrary.org/obo/UBERON_0001154)) and ([supplies](http://purl.obolibrary.org/obo/RO_0002178) some [ileum](http://purl.obolibrary.org/obo/UBERON_0002116)) and ([connecting branch of](http://purl.obolibrary.org/obo/RO_0002252) some [superior mesenteric artery](http://purl.obolibrary.org/obo/UBERON_0001182)) +- [ventral cochlear nucleus](http://purl.obolibrary.org/obo/UBERON_0002828) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus cochlearis anterior" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) -- [ileocolic artery](http://purl.obolibrary.org/obo/UBERON_0001197) SubClassOf [artery](http://purl.obolibrary.org/obo/UBERON_0001637) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:722" -- [ileocolic artery](http://purl.obolibrary.org/obo/UBERON_0001197) SubClassOf [connecting branch of](http://purl.obolibrary.org/obo/RO_0002252) some [superior mesenteric artery](http://purl.obolibrary.org/obo/UBERON_0001182) +- [ventral cochlear nucleus](http://purl.obolibrary.org/obo/UBERON_0002828) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus cochlearis ventralis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:722" -### ilioischiadic foramen `http://purl.obolibrary.org/obo/UBERON_0018326` -#### Removed -- [ilioischiadic foramen](http://purl.obolibrary.org/obo/UBERON_0018326) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UBERONTEMP:63e09c69-ac98-49ba-b232-2da5c7b19019" +- [ventral cochlear nucleus](http://purl.obolibrary.org/obo/UBERON_0002828) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus acustici accessorici" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:722" -### inferior suprarenal artery `http://purl.obolibrary.org/obo/UBERON_0002056` +### ventral funiculus of spinal cord `http://purl.obolibrary.org/obo/UBERON_0002180` #### Removed -- [inferior suprarenal artery](http://purl.obolibrary.org/obo/UBERON_0002056) EquivalentTo [suprarenal artery](http://purl.obolibrary.org/obo/UBERON_0005624) and ([branching part of](http://purl.obolibrary.org/obo/RO_0002380) some [renal artery](http://purl.obolibrary.org/obo/UBERON_0001184)) +- [ventral funiculus of spinal cord](http://purl.obolibrary.org/obo/UBERON_0002180) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "funiculus anterior medullae spinalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:74003" -- [inferior suprarenal artery](http://purl.obolibrary.org/obo/UBERON_0002056) SubClassOf [systemic artery](http://purl.obolibrary.org/obo/UBERON_0004573) + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) -- [inferior suprarenal artery](http://purl.obolibrary.org/obo/UBERON_0002056) SubClassOf [branching part of](http://purl.obolibrary.org/obo/RO_0002380) some [renal artery](http://purl.obolibrary.org/obo/UBERON_0001184) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" #### Added -- [inferior suprarenal artery](http://purl.obolibrary.org/obo/UBERON_0002056) EquivalentTo [suprarenal artery](http://purl.obolibrary.org/obo/UBERON_0005624) and ([connecting branch of](http://purl.obolibrary.org/obo/RO_0002252) some [renal artery](http://purl.obolibrary.org/obo/UBERON_0001184)) +- [ventral funiculus of spinal cord](http://purl.obolibrary.org/obo/UBERON_0002180) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "funiculus anterior medullae spinalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) -- [inferior suprarenal artery](http://purl.obolibrary.org/obo/UBERON_0002056) SubClassOf [connecting branch of](http://purl.obolibrary.org/obo/RO_0002252) some [renal artery](http://purl.obolibrary.org/obo/UBERON_0001184) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:74003" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" -### inferior vesical artery `http://purl.obolibrary.org/obo/UBERON_0001311` + +### ventral horn of spinal cord `http://purl.obolibrary.org/obo/UBERON_0002257` #### Removed -- [inferior vesical artery](http://purl.obolibrary.org/obo/UBERON_0001311) SubClassOf [systemic artery](http://purl.obolibrary.org/obo/UBERON_0004573) +- [ventral horn of spinal cord](http://purl.obolibrary.org/obo/UBERON_0002257) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cornu anterius medullae spinalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Anterior_horn_of_spinal_cord" -- [inferior vesical artery](http://purl.obolibrary.org/obo/UBERON_0001311) SubClassOf [branching part of](http://purl.obolibrary.org/obo/RO_0002380) some [internal iliac artery](http://purl.obolibrary.org/obo/UBERON_0001309) + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) -#### Added -- [inferior vesical artery](http://purl.obolibrary.org/obo/UBERON_0001311) SubClassOf [connecting branch of](http://purl.obolibrary.org/obo/RO_0002252) some [internal iliac artery](http://purl.obolibrary.org/obo/UBERON_0001309) +- [ventral horn of spinal cord](http://purl.obolibrary.org/obo/UBERON_0002257) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "columna grisea anterior medullae spinalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" -### intermediate cell of urothelium `http://purl.obolibrary.org/obo/CL_4030055` -#### Removed -- [intermediate cell of urothelium](http://purl.obolibrary.org/obo/CL_4030055) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:256541" -- [intermediate cell of urothelium](http://purl.obolibrary.org/obo/CL_4030055) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [human_reference_atlas](http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas) +#### Added +- [ventral horn of spinal cord](http://purl.obolibrary.org/obo/UBERON_0002257) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "cornu anterius medullae spinalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Anterior_horn_of_spinal_cord" +- [ventral horn of spinal cord](http://purl.obolibrary.org/obo/UBERON_0002257) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "columna grisea anterior medullae spinalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) -### internal thoracic artery `http://purl.obolibrary.org/obo/UBERON_0002456` -#### Removed -- [internal thoracic artery](http://purl.obolibrary.org/obo/UBERON_0002456) SubClassOf [branching part of](http://purl.obolibrary.org/obo/RO_0002380) some [subclavian artery](http://purl.obolibrary.org/obo/UBERON_0001533) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" -#### Added -- [internal thoracic artery](http://purl.obolibrary.org/obo/UBERON_0002456) SubClassOf [connecting branch of](http://purl.obolibrary.org/obo/RO_0002252) some [subclavian artery](http://purl.obolibrary.org/obo/UBERON_0001533) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:256541" -### jaw mesenchyme `http://purl.obolibrary.org/obo/UBERON_0034995` +### ventral striatum `http://purl.obolibrary.org/obo/UBERON_0005403` #### Removed -- [jaw mesenchyme](http://purl.obolibrary.org/obo/UBERON_0034995) SubClassOf [head mesenchyme](http://purl.obolibrary.org/obo/UBERON_0005253) +- [ventral striatum](http://purl.obolibrary.org/obo/UBERON_0005403) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D066328" #### Added -- [jaw mesenchyme](http://purl.obolibrary.org/obo/UBERON_0034995) SubClassOf [mesenchyme](http://purl.obolibrary.org/obo/UBERON_0003104) +- [ventral striatum](http://purl.obolibrary.org/obo/UBERON_0005403) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D066328" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + - [author_id](https://w3id.org/sssom/author_id) [0000-0001-9439-5346](https://orcid.org/0000-0001-9439-5346) -### jejunal artery `http://purl.obolibrary.org/obo/UBERON_0018255` -#### Removed -- [jejunal artery](http://purl.obolibrary.org/obo/UBERON_0018255) EquivalentTo [artery](http://purl.obolibrary.org/obo/UBERON_0001637) and ([supplies](http://purl.obolibrary.org/obo/RO_0002178) some [jejunum](http://purl.obolibrary.org/obo/UBERON_0002115)) and ([branching part of](http://purl.obolibrary.org/obo/RO_0002380) some [superior mesenteric artery](http://purl.obolibrary.org/obo/UBERON_0001182)) + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" -- [jejunal artery](http://purl.obolibrary.org/obo/UBERON_0018255) SubClassOf [branching part of](http://purl.obolibrary.org/obo/RO_0002380) some [superior mesenteric artery](http://purl.obolibrary.org/obo/UBERON_0001182) -- [jejunal artery](http://purl.obolibrary.org/obo/UBERON_0018255) SubClassOf [systemic artery](http://purl.obolibrary.org/obo/UBERON_0004573) +### ventricular cardiac muscle cell `http://purl.obolibrary.org/obo/CL_2000046` #### Added -- [jejunal artery](http://purl.obolibrary.org/obo/UBERON_0018255) EquivalentTo [artery](http://purl.obolibrary.org/obo/UBERON_0001637) and ([supplies](http://purl.obolibrary.org/obo/RO_0002178) some [jejunum](http://purl.obolibrary.org/obo/UBERON_0002115)) and ([connecting branch of](http://purl.obolibrary.org/obo/RO_0002252) some [superior mesenteric artery](http://purl.obolibrary.org/obo/UBERON_0001182)) - -- [jejunal artery](http://purl.obolibrary.org/obo/UBERON_0018255) SubClassOf [artery](http://purl.obolibrary.org/obo/UBERON_0001637) +- [ventricular cardiac muscle cell](http://purl.obolibrary.org/obo/CL_2000046) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) -- [jejunal artery](http://purl.obolibrary.org/obo/UBERON_0018255) SubClassOf [connecting branch of](http://purl.obolibrary.org/obo/RO_0002252) some [superior mesenteric artery](http://purl.obolibrary.org/obo/UBERON_0001182) - -### keratocyte `http://purl.obolibrary.org/obo/CL_0002363` +### ventricular system of central nervous system `http://purl.obolibrary.org/obo/UBERON_0005281` #### Removed -- [keratocyte](http://purl.obolibrary.org/obo/CL_0002363) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A keratocyte is a specialized fibroblast residing in the cornea stroma that has a flattened, dendritic cell located between the lamellae with a large flattened nucleus and lengthy processes which communicate with neighboring cells. This corneal layer, representing about 85-90% of corneal thickness, is built up from highly regular collagenous lamellae and extracellular matrix components. Keratocytes play the major role in keeping it transparent, healing its wounds, and synthesizing its components. This cell type secretes collagen I, V, VI, and keratin sulfate." - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:tfm" +- [ventricular system of central nervous system](http://purl.obolibrary.org/obo/UBERON_0005281) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ventriculi cerebri" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Ventricular_system" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:978-0-7020-2958-5" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) #### Added -- [keratocyte](http://purl.obolibrary.org/obo/CL_0002363) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A keratocyte is a specialized fibroblast residing in the cornea stroma that has a flattened, dendritic morphology; located between the lamellae with a large flattened nucleus, and lengthy processes which communicate with neighboring cells. This corneal layer, representing about 85-90% of corneal thickness, is built up from highly regular collagenous lamellae and extracellular matrix components. Keratocytes play the major role in keeping it transparent, healing its wounds, and synthesizing its components. This cell type secretes collagen I, V, VI, and keratan sulfate." - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "GOC:tfm" +- [ventricular system of central nervous system](http://purl.obolibrary.org/obo/UBERON_0005281) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "ventriculi cerebri" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Ventricular_system" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:9780702029585" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) -### kidney afferent arteriole endothelial cell `http://purl.obolibrary.org/obo/CL_1001096` +### venule `http://purl.obolibrary.org/obo/UBERON_0001979` #### Removed -- [kidney afferent arteriole endothelial cell](http://purl.obolibrary.org/obo/CL_1001096) SubClassOf [interlobulary artery endothelial cell](http://purl.obolibrary.org/obo/CL_1001216) +- [venule](http://purl.obolibrary.org/obo/UBERON_0001979) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "venula" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Venule" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) #### Added -- [kidney afferent arteriole endothelial cell](http://purl.obolibrary.org/obo/CL_1001096) SubClassOf [endothelial cell of artery](http://purl.obolibrary.org/obo/CL_1000413) +- [venule](http://purl.obolibrary.org/obo/UBERON_0001979) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "venula" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Venule" -### kidney afferent arteriole smooth muscle cell `http://purl.obolibrary.org/obo/CL_1001097` -#### Removed -- [kidney afferent arteriole smooth muscle cell](http://purl.obolibrary.org/obo/CL_1001097) SubClassOf [interlobulary artery smooth muscle cell](http://purl.obolibrary.org/obo/CL_1001217) +### vermiform appendix `http://purl.obolibrary.org/obo/UBERON_0001154` +#### Removed +- [vermiform appendix](http://purl.obolibrary.org/obo/UBERON_0001154) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "appendix vermiformis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Vermiform_appendix" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) -### kidney arcuate artery `http://purl.obolibrary.org/obo/UBERON_0001552` -#### Removed -- [kidney arcuate artery](http://purl.obolibrary.org/obo/UBERON_0001552) SubClassOf [branching part of](http://purl.obolibrary.org/obo/RO_0002380) some [interlobar artery](http://purl.obolibrary.org/obo/UBERON_0009885) +- [vermiform appendix](http://purl.obolibrary.org/obo/UBERON_0001154) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "appendix vermiformis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:14542" -#### Added -- [kidney arcuate artery](http://purl.obolibrary.org/obo/UBERON_0001552) SubClassOf [connecting branch of](http://purl.obolibrary.org/obo/RO_0002252) some [interlobar artery](http://purl.obolibrary.org/obo/UBERON_0009885) + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" -### lacrimal artery `http://purl.obolibrary.org/obo/UBERON_0001622` -#### Removed -- [lacrimal artery](http://purl.obolibrary.org/obo/UBERON_0001622) SubClassOf [branching part of](http://purl.obolibrary.org/obo/RO_0002380) some [ophthalmic artery](http://purl.obolibrary.org/obo/UBERON_0001619) - - [source](http://www.geneontology.org/formats/oboInOwl#source) "FMA" +#### Added +- [vermiform appendix](http://purl.obolibrary.org/obo/UBERON_0001154) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "appendix vermiformis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Vermiform_appendix" -- [lacrimal artery](http://purl.obolibrary.org/obo/UBERON_0001622) SubClassOf [systemic artery](http://purl.obolibrary.org/obo/UBERON_0004573) + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) -- [lacrimal artery](http://purl.obolibrary.org/obo/UBERON_0001622) SubClassOf [head blood vessel](http://purl.obolibrary.org/obo/UBERON_0003496) +- [vermiform appendix](http://purl.obolibrary.org/obo/UBERON_0001154) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "appendix vermiformis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:14542" -#### Added -- [lacrimal artery](http://purl.obolibrary.org/obo/UBERON_0001622) SubClassOf [connecting branch of](http://purl.obolibrary.org/obo/RO_0002252) some [ophthalmic artery](http://purl.obolibrary.org/obo/UBERON_0001619) - - [source](http://www.geneontology.org/formats/oboInOwl#source) "FMA" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) -- [lacrimal artery](http://purl.obolibrary.org/obo/UBERON_0001622) SubClassOf [artery](http://purl.obolibrary.org/obo/UBERON_0001637) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" -### lacrimal canaliculus `http://purl.obolibrary.org/obo/UBERON_0001770` +### vertebra `http://purl.obolibrary.org/obo/UBERON_0002412` #### Removed -- [lacrimal canaliculus](http://purl.obolibrary.org/obo/UBERON_0001770) [editor note](http://purl.obolibrary.org/obo/IAO_0000116) "TODO - resolve lacrimal canaliculus vs lacrimal duct" +- [vertebra](http://purl.obolibrary.org/obo/UBERON_0002412) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0006196" + - [contributor](http://purl.org/dc/terms/contributor) "https://orcid.org/0000-0003-4423-4370" #### Added -- [lacrimal canaliculus](http://purl.obolibrary.org/obo/UBERON_0001770) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "lacrimal duct" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:1587341026" +- [vertebra](http://purl.obolibrary.org/obo/UBERON_0002412) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0006196" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "https://www.bartleby.com/lit-hub/anatomy-of-the-human-body/fig-896/" + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" + - [author_id](https://w3id.org/sssom/author_id) [0000-0003-4423-4370](https://orcid.org/0000-0003-4423-4370) -### lacrimal drainage system `http://purl.obolibrary.org/obo/UBERON_0001850` + +### vertebral bone 1 `http://purl.obolibrary.org/obo/UBERON_0001092` #### Removed -- [lacrimal drainage system](http://purl.obolibrary.org/obo/UBERON_0001850) [editor note](http://purl.obolibrary.org/obo/IAO_0000116) "TODO - resolve lacrimal canaliculus vs larcimal duct" +- [vertebral bone 1](http://purl.obolibrary.org/obo/UBERON_0001092) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "atlas [C I]" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:12519" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" -### left eye `http://purl.obolibrary.org/obo/UBERON_0004548` -#### Removed -- [left eye](http://purl.obolibrary.org/obo/UBERON_0004548) [depiction](http://xmlns.com/foaf/0.1/depiction) "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Eye_L.glb"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) +#### Added +- [vertebral bone 1](http://purl.obolibrary.org/obo/UBERON_0001092) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "atlas [C I]" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) -- [left eye](http://purl.obolibrary.org/obo/UBERON_0004548) [depiction](http://xmlns.com/foaf/0.1/depiction) "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Eye_L.glb"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:12519" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" -### left lung `http://purl.obolibrary.org/obo/UBERON_0002168` +### vertebral bone 2 `http://purl.obolibrary.org/obo/UBERON_0001093` #### Removed -- [left lung](http://purl.obolibrary.org/obo/UBERON_0002168) [depiction](http://xmlns.com/foaf/0.1/depiction) "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Lung.glb"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) - -- [left lung](http://purl.obolibrary.org/obo/UBERON_0002168) [depiction](http://xmlns.com/foaf/0.1/depiction) "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Lung.glb"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) +- [vertebral bone 2](http://purl.obolibrary.org/obo/UBERON_0001093) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "axis [C II]" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:12520" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" -### lobar bronchus of left lung `http://purl.obolibrary.org/obo/UBERON_0003405` -#### Removed -- [lobar bronchus of left lung](http://purl.obolibrary.org/obo/UBERON_0003405) [depiction](http://xmlns.com/foaf/0.1/depiction) "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Lung.glb"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) +#### Added +- [vertebral bone 2](http://purl.obolibrary.org/obo/UBERON_0001093) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "axis [C II]" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) -- [lobar bronchus of left lung](http://purl.obolibrary.org/obo/UBERON_0003405) [depiction](http://xmlns.com/foaf/0.1/depiction) "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Lung.glb"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:12520" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" -### lobar bronchus of right lung `http://purl.obolibrary.org/obo/UBERON_0003404` +### vertebral canal `http://purl.obolibrary.org/obo/UBERON_0006692` #### Removed -- [lobar bronchus of right lung](http://purl.obolibrary.org/obo/UBERON_0003404) [depiction](http://xmlns.com/foaf/0.1/depiction) "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Lung.glb"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) - -- [lobar bronchus of right lung](http://purl.obolibrary.org/obo/UBERON_0003404) [depiction](http://xmlns.com/foaf/0.1/depiction) "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Lung.glb"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) +- [vertebral canal](http://purl.obolibrary.org/obo/UBERON_0006692) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "c. vertebralis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Spinal_canal" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) +#### Added +- [vertebral canal](http://purl.obolibrary.org/obo/UBERON_0006692) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D013115" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [LexicalMatching](https://w3id.org/semapv/vocab/LexicalMatching) -### lung `http://purl.obolibrary.org/obo/UBERON_0002048` -#### Removed -- [lung](http://purl.obolibrary.org/obo/UBERON_0002048) [depiction](http://xmlns.com/foaf/0.1/depiction) "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Lung.glb"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" -- [lung](http://purl.obolibrary.org/obo/UBERON_0002048) [depiction](http://xmlns.com/foaf/0.1/depiction) "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Lung.glb"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) +- [vertebral canal](http://purl.obolibrary.org/obo/UBERON_0006692) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "c. vertebralis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Spinal_canal" -### medial circumflex femoral artery `http://purl.obolibrary.org/obo/UBERON_0001356` +### vertebral foramen `http://purl.obolibrary.org/obo/UBERON_0001131` #### Removed -- [medial circumflex femoral artery](http://purl.obolibrary.org/obo/UBERON_0001356) SubClassOf [branching part of](http://purl.obolibrary.org/obo/RO_0002380) some [deep femoral artery](http://purl.obolibrary.org/obo/UBERON_0001355) - - [source](http://www.geneontology.org/formats/oboInOwl#source) "FMA" +- [vertebral foramen](http://purl.obolibrary.org/obo/UBERON_0001131) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "foramen vertebrale" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Vertebral_foramen" -- [medial circumflex femoral artery](http://purl.obolibrary.org/obo/UBERON_0001356) SubClassOf [systemic artery](http://purl.obolibrary.org/obo/UBERON_0004573) + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) #### Added -- [medial circumflex femoral artery](http://purl.obolibrary.org/obo/UBERON_0001356) SubClassOf [artery](http://purl.obolibrary.org/obo/UBERON_0001637) +- [vertebral foramen](http://purl.obolibrary.org/obo/UBERON_0001131) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "foramen vertebrale" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Vertebral_foramen" -- [medial circumflex femoral artery](http://purl.obolibrary.org/obo/UBERON_0001356) SubClassOf [connecting branch of](http://purl.obolibrary.org/obo/RO_0002252) some [deep femoral artery](http://purl.obolibrary.org/obo/UBERON_0001355) - - [source](http://www.geneontology.org/formats/oboInOwl#source) "FMA" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) -### medullary arteriole of lymph node `http://purl.obolibrary.org/obo/UBERON_8410035` +### vertebral foramen of atlas `http://purl.obolibrary.org/obo/UBERON_0000219` #### Removed -- [medullary arteriole of lymph node](http://purl.obolibrary.org/obo/UBERON_8410035) SubClassOf [branching part of](http://purl.obolibrary.org/obo/RO_0002380) some [lymph node artery](http://purl.obolibrary.org/obo/UBERON_8410034) +- [vertebral foramen of atlas](http://purl.obolibrary.org/obo/UBERON_0000219) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "." + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Atlas_(anatomy)#Vertebral_foramen" -#### Added -- [medullary arteriole of lymph node](http://purl.obolibrary.org/obo/UBERON_8410035) SubClassOf [connecting branch of](http://purl.obolibrary.org/obo/RO_0002252) some [lymph node artery](http://purl.obolibrary.org/obo/UBERON_8410034) -### mesenchyme of tongue `http://purl.obolibrary.org/obo/UBERON_0003416` +### vesical artery `http://purl.obolibrary.org/obo/UBERON_0009027` #### Removed -- [mesenchyme of tongue](http://purl.obolibrary.org/obo/UBERON_0003416) SubClassOf [head mesenchyme](http://purl.obolibrary.org/obo/UBERON_0005253) +- [vesical artery](http://purl.obolibrary.org/obo/UBERON_0009027) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "arteria vesicali" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) #### Added -- [mesenchyme of tongue](http://purl.obolibrary.org/obo/UBERON_0003416) SubClassOf [mesenchyme](http://purl.obolibrary.org/obo/UBERON_0003104) +- [vesical artery](http://purl.obolibrary.org/obo/UBERON_0009027) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "arteria vesicali" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) -### middle colic artery `http://purl.obolibrary.org/obo/UBERON_0001196` +### vesical vein `http://purl.obolibrary.org/obo/UBERON_0002460` #### Removed -- [middle colic artery](http://purl.obolibrary.org/obo/UBERON_0001196) EquivalentTo [artery](http://purl.obolibrary.org/obo/UBERON_0001637) and ([supplies](http://purl.obolibrary.org/obo/RO_0002178) some [transverse colon](http://purl.obolibrary.org/obo/UBERON_0001157)) and ([branching part of](http://purl.obolibrary.org/obo/RO_0002380) some [superior mesenteric artery](http://purl.obolibrary.org/obo/UBERON_0001182)) +- [vesical vein](http://purl.obolibrary.org/obo/UBERON_0002460) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "venae vesicales" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:70911" -- [middle colic artery](http://purl.obolibrary.org/obo/UBERON_0001196) SubClassOf [branching part of](http://purl.obolibrary.org/obo/RO_0002380) some [superior mesenteric artery](http://purl.obolibrary.org/obo/UBERON_0001182) + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) -- [middle colic artery](http://purl.obolibrary.org/obo/UBERON_0001196) SubClassOf [systemic artery](http://purl.obolibrary.org/obo/UBERON_0004573) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" #### Added -- [middle colic artery](http://purl.obolibrary.org/obo/UBERON_0001196) EquivalentTo [artery](http://purl.obolibrary.org/obo/UBERON_0001637) and ([supplies](http://purl.obolibrary.org/obo/RO_0002178) some [transverse colon](http://purl.obolibrary.org/obo/UBERON_0001157)) and ([connecting branch of](http://purl.obolibrary.org/obo/RO_0002252) some [superior mesenteric artery](http://purl.obolibrary.org/obo/UBERON_0001182)) +- [vesical vein](http://purl.obolibrary.org/obo/UBERON_0002460) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "venae vesicales" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) -- [middle colic artery](http://purl.obolibrary.org/obo/UBERON_0001196) SubClassOf [connecting branch of](http://purl.obolibrary.org/obo/RO_0002252) some [superior mesenteric artery](http://purl.obolibrary.org/obo/UBERON_0001182) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:70911" -- [middle colic artery](http://purl.obolibrary.org/obo/UBERON_0001196) SubClassOf [artery](http://purl.obolibrary.org/obo/UBERON_0001637) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" -### mouth `http://purl.obolibrary.org/obo/UBERON_0000165` +### vestibular labyrinth `http://purl.obolibrary.org/obo/UBERON_0001862` #### Removed -- [mouth](http://purl.obolibrary.org/obo/UBERON_0000165) SubClassOf [overlaps](http://purl.obolibrary.org/obo/RO_0002131) some [respiratory system](http://purl.obolibrary.org/obo/UBERON_0001004) - - [notes](http://www.geneontology.org/formats/oboInOwl#notes) "exceptions in some taxa" +- [vestibular labyrinth](http://purl.obolibrary.org/obo/UBERON_0001862) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D014722" -- [mouth](http://purl.obolibrary.org/obo/UBERON_0000165) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [head](http://purl.obolibrary.org/obo/UBERON_0000033) +#### Added +- [vestibular labyrinth](http://purl.obolibrary.org/obo/UBERON_0001862) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D014722" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [author_id](https://w3id.org/sssom/author_id) [0000-0001-9439-5346](https://orcid.org/0000-0001-9439-5346) + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" -### musculo-phrenic artery `http://purl.obolibrary.org/obo/UBERON_0006632` +### vestibulocochlear ganglion `http://purl.obolibrary.org/obo/UBERON_0002827` #### Removed -- [musculo-phrenic artery](http://purl.obolibrary.org/obo/UBERON_0006632) EquivalentTo [artery](http://purl.obolibrary.org/obo/UBERON_0001637) and ([supplies](http://purl.obolibrary.org/obo/RO_0002178) some [diaphragm](http://purl.obolibrary.org/obo/UBERON_0001103)) and ([branching part of](http://purl.obolibrary.org/obo/RO_0002380) some [internal thoracic artery](http://purl.obolibrary.org/obo/UBERON_0002456)) +- [vestibulocochlear ganglion](http://purl.obolibrary.org/obo/UBERON_0002827) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus nervi oculomotorii, pars ventralis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:496" -- [musculo-phrenic artery](http://purl.obolibrary.org/obo/UBERON_0006632) SubClassOf [branching part of](http://purl.obolibrary.org/obo/RO_0002380) some [internal thoracic artery](http://purl.obolibrary.org/obo/UBERON_0002456) + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) -#### Added -- [musculo-phrenic artery](http://purl.obolibrary.org/obo/UBERON_0006632) EquivalentTo [artery](http://purl.obolibrary.org/obo/UBERON_0001637) and ([supplies](http://purl.obolibrary.org/obo/RO_0002178) some [diaphragm](http://purl.obolibrary.org/obo/UBERON_0001103)) and ([connecting branch of](http://purl.obolibrary.org/obo/RO_0002252) some [internal thoracic artery](http://purl.obolibrary.org/obo/UBERON_0002456)) +- [vestibulocochlear ganglion](http://purl.obolibrary.org/obo/UBERON_0002827) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus nervi oculomotorii ventrolateralis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:496" -- [musculo-phrenic artery](http://purl.obolibrary.org/obo/UBERON_0006632) SubClassOf [connecting branch of](http://purl.obolibrary.org/obo/RO_0002252) some [internal thoracic artery](http://purl.obolibrary.org/obo/UBERON_0002456) + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) +#### Added +- [vestibulocochlear ganglion](http://purl.obolibrary.org/obo/UBERON_0002827) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus nervi oculomotorii, pars ventralis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) -### myeloid lineage restricted progenitor cell `http://purl.obolibrary.org/obo/CL_0000839` + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:496" -#### Added -- [myeloid lineage restricted progenitor cell](http://purl.obolibrary.org/obo/CL_0000839) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606) +- [vestibulocochlear ganglion](http://purl.obolibrary.org/obo/UBERON_0002827) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nucleus nervi oculomotorii ventrolateralis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) -- [myeloid lineage restricted progenitor cell](http://purl.obolibrary.org/obo/CL_0000839) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [human_reference_atlas](http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:496" -### nasal skeleton `http://purl.obolibrary.org/obo/UBERON_0006813` +### vestibulocochlear nerve `http://purl.obolibrary.org/obo/UBERON_0001648` #### Removed -- [nasal skeleton](http://purl.obolibrary.org/obo/UBERON_0006813) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [facial skeleton](http://purl.obolibrary.org/obo/UBERON_0011156) +- [vestibulocochlear nerve](http://purl.obolibrary.org/obo/UBERON_0001648) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nervus vestibulocochlearis [viii]" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:50869" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" -### nasolacrimal duct `http://purl.obolibrary.org/obo/UBERON_0002392` +- [vestibulocochlear nerve](http://purl.obolibrary.org/obo/UBERON_0001648) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nervus octavus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:553" -#### Added -- [nasolacrimal duct](http://purl.obolibrary.org/obo/UBERON_0002392) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "lacrimal duct" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:30285382" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) +- [vestibulocochlear nerve](http://purl.obolibrary.org/obo/UBERON_0001648) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nervus statoacusticus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:553" -### neocortex `http://purl.obolibrary.org/obo/UBERON_0001950` -#### Removed -- [neocortex](http://purl.obolibrary.org/obo/UBERON_0001950) SubClassOf [only in taxon](http://purl.obolibrary.org/obo/RO_0002160) some [Mammalia](http://purl.obolibrary.org/obo/NCBITaxon_40674) - - [source](http://www.geneontology.org/formats/oboInOwl#source) "Wikipedia" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) #### Added -- [neocortex](http://purl.obolibrary.org/obo/UBERON_0001950) SubClassOf [only in taxon](http://purl.obolibrary.org/obo/RO_0002160) some [Vertebrata ](http://purl.obolibrary.org/obo/NCBITaxon_7742) - - [source](http://www.geneontology.org/formats/oboInOwl#source) "Wikipedia" +- [vestibulocochlear nerve](http://purl.obolibrary.org/obo/UBERON_0001648) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "nervus vestibulocochlearis [viii]" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:50869" -### neurocranium bone `http://purl.obolibrary.org/obo/UBERON_0011164` + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" -#### Added -- [neurocranium bone](http://purl.obolibrary.org/obo/UBERON_0011164) SubClassOf [head bone](http://purl.obolibrary.org/obo/UBERON_0003457) +- [vestibulocochlear nerve](http://purl.obolibrary.org/obo/UBERON_0001648) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nervus octavus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:553" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) -### occipital artery `http://purl.obolibrary.org/obo/UBERON_0001613` -#### Removed -- [occipital artery](http://purl.obolibrary.org/obo/UBERON_0001613) EquivalentTo [artery](http://purl.obolibrary.org/obo/UBERON_0001637) and ([supplies](http://purl.obolibrary.org/obo/RO_0002178) some [scalp](http://purl.obolibrary.org/obo/UBERON_0000403)) and ([supplies](http://purl.obolibrary.org/obo/RO_0002178) some [muscle of neck](http://purl.obolibrary.org/obo/UBERON_0002377)) and ([branching part of](http://purl.obolibrary.org/obo/RO_0002380) some [external carotid artery](http://purl.obolibrary.org/obo/UBERON_0001070)) +- [vestibulocochlear nerve](http://purl.obolibrary.org/obo/UBERON_0001648) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "nervus statoacusticus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:553" -#### Added -- [occipital artery](http://purl.obolibrary.org/obo/UBERON_0001613) EquivalentTo [artery](http://purl.obolibrary.org/obo/UBERON_0001637) and ([supplies](http://purl.obolibrary.org/obo/RO_0002178) some [scalp](http://purl.obolibrary.org/obo/UBERON_0000403)) and ([supplies](http://purl.obolibrary.org/obo/RO_0002178) some [muscle of neck](http://purl.obolibrary.org/obo/UBERON_0002377)) and ([connecting branch of](http://purl.obolibrary.org/obo/RO_0002252) some [external carotid artery](http://purl.obolibrary.org/obo/UBERON_0001070)) + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) -### ophthalmic artery `http://purl.obolibrary.org/obo/UBERON_0001619` +### vestibulocochlear nerve root `http://purl.obolibrary.org/obo/UBERON_0002731` #### Removed -- [ophthalmic artery](http://purl.obolibrary.org/obo/UBERON_0001619) SubClassOf [systemic artery](http://purl.obolibrary.org/obo/UBERON_0004573) +- [vestibulocochlear nerve root](http://purl.obolibrary.org/obo/UBERON_0002731) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "fibrae nervi statoacustici" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:72499" -- [ophthalmic artery](http://purl.obolibrary.org/obo/UBERON_0001619) SubClassOf [branching part of](http://purl.obolibrary.org/obo/RO_0002380) some [internal carotid artery](http://purl.obolibrary.org/obo/UBERON_0001532) + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) -- [ophthalmic artery](http://purl.obolibrary.org/obo/UBERON_0001619) SubClassOf [head blood vessel](http://purl.obolibrary.org/obo/UBERON_0003496) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" #### Added -- [ophthalmic artery](http://purl.obolibrary.org/obo/UBERON_0001619) SubClassOf [artery](http://purl.obolibrary.org/obo/UBERON_0001637) +- [vestibulocochlear nerve root](http://purl.obolibrary.org/obo/UBERON_0002731) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "fibrae nervi statoacustici" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) -- [ophthalmic artery](http://purl.obolibrary.org/obo/UBERON_0001619) SubClassOf [connecting branch of](http://purl.obolibrary.org/obo/RO_0002252) some [internal carotid artery](http://purl.obolibrary.org/obo/UBERON_0001532) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:72499" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" -### outer epithelium `http://purl.obolibrary.org/obo/UBERON_0007376` + +### vip GABAergic cortical interneuron `http://purl.obolibrary.org/obo/CL_4023016` #### Added -- [outer epithelium](http://purl.obolibrary.org/obo/UBERON_0007376) SubClassOf [only in taxon](http://purl.obolibrary.org/obo/RO_0002160) some [Eumetazoa](http://purl.obolibrary.org/obo/NCBITaxon_6072) - - [source](http://www.geneontology.org/formats/oboInOwl#source) "Wikipedia:Epidermis_(zoology)" +- [vip GABAergic cortical interneuron](http://purl.obolibrary.org/obo/CL_4023016) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) -### pancreatic artery `http://purl.obolibrary.org/obo/UBERON_0039261` +### visceral pleura `http://purl.obolibrary.org/obo/UBERON_0002401` #### Removed -- [pancreatic artery](http://purl.obolibrary.org/obo/UBERON_0039261) SubClassOf [systemic artery](http://purl.obolibrary.org/obo/UBERON_0004573) +- [visceral pleura](http://purl.obolibrary.org/obo/UBERON_0002401) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pleura pulmonalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:9734" -- [pancreatic artery](http://purl.obolibrary.org/obo/UBERON_0039261) SubClassOf [branching part of](http://purl.obolibrary.org/obo/RO_0002380) some [splenic artery](http://purl.obolibrary.org/obo/UBERON_0001194) + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) -#### Added -- [pancreatic artery](http://purl.obolibrary.org/obo/UBERON_0039261) SubClassOf [connecting branch of](http://purl.obolibrary.org/obo/RO_0002252) some [splenic artery](http://purl.obolibrary.org/obo/UBERON_0001194) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" -- [pancreatic artery](http://purl.obolibrary.org/obo/UBERON_0039261) SubClassOf [artery](http://purl.obolibrary.org/obo/UBERON_0001637) +- [visceral pleura](http://purl.obolibrary.org/obo/UBERON_0002401) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pleura visceralis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Visceral_pleura" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) -### pericardial cavity `http://purl.obolibrary.org/obo/UBERON_0001074` -#### Removed -- [pericardial cavity](http://purl.obolibrary.org/obo/UBERON_0001074) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [NCBITaxon_7718](http://purl.obolibrary.org/obo/NCBITaxon_7718) - - [source](http://www.geneontology.org/formats/oboInOwl#source) "PMID:20959416" +#### Added +- [visceral pleura](http://purl.obolibrary.org/obo/UBERON_0002401) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pleura pulmonalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:9734" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" -### placental blood `http://purl.obolibrary.org/obo/UBERON_8470000` -#### Removed -- [placental blood](http://purl.obolibrary.org/obo/UBERON_8470000) [contributor](http://purl.org/dc/terms/contributor) [0000-0002-1773-2692](https://orcid.org/0000-0002-1773-2692) +- [visceral pleura](http://purl.obolibrary.org/obo/UBERON_0002401) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pleura visceralis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Visceral_pleura" -### posterior communicating artery `http://purl.obolibrary.org/obo/UBERON_0001628` +### visceral serous pericardium `http://purl.obolibrary.org/obo/UBERON_0002425` #### Removed -- [posterior communicating artery](http://purl.obolibrary.org/obo/UBERON_0001628) EquivalentTo [communicating artery](http://purl.obolibrary.org/obo/UBERON_0006347) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [circle of Willis](http://purl.obolibrary.org/obo/UBERON_0003709)) and ([branching part of](http://purl.obolibrary.org/obo/RO_0002380) some [internal carotid artery](http://purl.obolibrary.org/obo/UBERON_0001532)) - -- [posterior communicating artery](http://purl.obolibrary.org/obo/UBERON_0001628) SubClassOf [branching part of](http://purl.obolibrary.org/obo/RO_0002380) some [internal carotid artery](http://purl.obolibrary.org/obo/UBERON_0001532) - - [source](http://www.geneontology.org/formats/oboInOwl#source) "ZFA" +- [visceral serous pericardium](http://purl.obolibrary.org/obo/UBERON_0002425) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lamina visceralis pericardii serosi" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Epicardium" - - [source](http://www.geneontology.org/formats/oboInOwl#source) "FMA" - -- [posterior communicating artery](http://purl.obolibrary.org/obo/UBERON_0001628) SubClassOf [head blood vessel](http://purl.obolibrary.org/obo/UBERON_0003496) + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) #### Added -- [posterior communicating artery](http://purl.obolibrary.org/obo/UBERON_0001628) EquivalentTo [communicating artery](http://purl.obolibrary.org/obo/UBERON_0006347) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [circle of Willis](http://purl.obolibrary.org/obo/UBERON_0003709)) and ([connecting branch of](http://purl.obolibrary.org/obo/RO_0002252) some [internal carotid artery](http://purl.obolibrary.org/obo/UBERON_0001532)) - -- [posterior communicating artery](http://purl.obolibrary.org/obo/UBERON_0001628) SubClassOf [connecting branch of](http://purl.obolibrary.org/obo/RO_0002252) some [internal carotid artery](http://purl.obolibrary.org/obo/UBERON_0001532) - - [source](http://www.geneontology.org/formats/oboInOwl#source) "ZFA" +- [visceral serous pericardium](http://purl.obolibrary.org/obo/UBERON_0002425) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "lamina visceralis pericardii serosi" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) - - [source](http://www.geneontology.org/formats/oboInOwl#source) "FMA" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Epicardium" -### posterior lateral line `http://purl.obolibrary.org/obo/UBERON_0006334` -#### Removed -- [posterior lateral line](http://purl.obolibrary.org/obo/UBERON_0006334) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "HBA:4413" +### visceromotor neuron `http://purl.obolibrary.org/obo/CL_0005025` +#### Added +- [visceromotor neuron](http://purl.obolibrary.org/obo/CL_0005025) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [cellxgene_subset](http://purl.obolibrary.org/obo/cl#cellxgene_subset) -### posterior nasal aperture `http://purl.obolibrary.org/obo/UBERON_0004771` +### vitelline vein `http://purl.obolibrary.org/obo/UBERON_0005487` #### Removed -- [posterior nasal aperture](http://purl.obolibrary.org/obo/UBERON_0004771) SubClassOf [orifice of skull](http://purl.obolibrary.org/obo/UBERON_0036253) - - +- [vitelline vein](http://purl.obolibrary.org/obo/UBERON_0005487) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "vena vitellina" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Vitelline_veins" -### processual entity `http://purl.obolibrary.org/obo/UBERON_0000000` + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) #### Added -- [processual entity](http://purl.obolibrary.org/obo/UBERON_0000000) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BFO:0000003" +- [vitelline vein](http://purl.obolibrary.org/obo/UBERON_0005487) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "vena vitellina" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Vitelline_veins" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) -### proper hepatic artery `http://purl.obolibrary.org/obo/UBERON_0015480` -#### Removed -- [proper hepatic artery](http://purl.obolibrary.org/obo/UBERON_0015480) SubClassOf [systemic artery](http://purl.obolibrary.org/obo/UBERON_0004573) - -- [proper hepatic artery](http://purl.obolibrary.org/obo/UBERON_0015480) SubClassOf [branching part of](http://purl.obolibrary.org/obo/RO_0002380) some [common hepatic artery](http://purl.obolibrary.org/obo/UBERON_0005436) - - [source](http://www.geneontology.org/formats/oboInOwl#source) "FMA" -#### Added -- [proper hepatic artery](http://purl.obolibrary.org/obo/UBERON_0015480) SubClassOf [connecting branch of](http://purl.obolibrary.org/obo/RO_0002252) some [common hepatic artery](http://purl.obolibrary.org/obo/UBERON_0005436) - - [source](http://www.geneontology.org/formats/oboInOwl#source) "FMA" +### vitreous chamber of eyeball `http://purl.obolibrary.org/obo/UBERON_0001799` +#### Removed +- [vitreous chamber of eyeball](http://purl.obolibrary.org/obo/UBERON_0001799) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "camera postrema bulbi oculi" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:58848" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) -### pulmonary venous system `http://purl.obolibrary.org/obo/UBERON_0013127` + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" #### Added -- [pulmonary venous system](http://purl.obolibrary.org/obo/UBERON_0013127) [label](http://www.w3.org/2000/01/rdf-schema#label) "pulmonary venous system" +- [vitreous chamber of eyeball](http://purl.obolibrary.org/obo/UBERON_0001799) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "camera postrema bulbi oculi" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) -- [pulmonary venous system](http://purl.obolibrary.org/obo/UBERON_0013127) [UBPROP_0000001](http://purl.obolibrary.org/obo/UBPROP_0000001) "Pulmonary circulation is the half portion of the cardiovascular system which carries oxygen-depleted blood away from the heart, to the lungs, and returns oxygenated (oxygen-rich) blood back to the heart. The term pulmonary circulation is readily paired and contrasted with the systemic circulation. A separate system known as the bronchial circulation supplies blood to the tissue of the larger airways of the lung." - - [source](http://www.geneontology.org/formats/oboInOwl#source) "Wikipedia:Pulmonary_circulation" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:58848" -- [pulmonary venous system](http://purl.obolibrary.org/obo/UBERON_0013127) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pulmonary venous circulatory system" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" -- [pulmonary venous system](http://purl.obolibrary.org/obo/UBERON_0013127) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "The part of the venous system that drains the lungs[Kardong]." - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "ISBN:0073040584" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Pulmonary_venous_system" +### vitreous humor `http://purl.obolibrary.org/obo/UBERON_0001797` +#### Removed +- [vitreous humor](http://purl.obolibrary.org/obo/UBERON_0001797) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "humor vitreus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) -- [pulmonary venous system](http://purl.obolibrary.org/obo/UBERON_0013127) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "uberon" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" -- [pulmonary venous system](http://purl.obolibrary.org/obo/UBERON_0013127) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Pulmonary_venous_system" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:58822" -- [pulmonary venous system](http://purl.obolibrary.org/obo/UBERON_0013127) [id](http://www.geneontology.org/formats/oboInOwl#id) "UBERON:0013127" +#### Added +- [vitreous humor](http://purl.obolibrary.org/obo/UBERON_0001797) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "humor vitreus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) -- Class: [pulmonary venous system](http://purl.obolibrary.org/obo/UBERON_0013127) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" -- [pulmonary venous system](http://purl.obolibrary.org/obo/UBERON_0013127) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [venous system](http://purl.obolibrary.org/obo/UBERON_0004582) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:58822" -- [pulmonary venous system](http://purl.obolibrary.org/obo/UBERON_0013127) SubClassOf [channels_from](http://purl.obolibrary.org/obo/uberon/core#channels_from) some [lung vasculature](http://purl.obolibrary.org/obo/UBERON_0000102) +- [vitreous humor](http://purl.obolibrary.org/obo/UBERON_0001797) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D014822" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [LexicalMatching](https://w3id.org/semapv/vocab/LexicalMatching) -- [pulmonary venous system](http://purl.obolibrary.org/obo/UBERON_0013127) SubClassOf [vasculature](http://purl.obolibrary.org/obo/UBERON_0002049) + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" -### pulmonary venule `http://purl.obolibrary.org/obo/UBERON_8600024` +### vomer `http://purl.obolibrary.org/obo/UBERON_0002396` +#### Removed +- [vomer](http://purl.obolibrary.org/obo/UBERON_0002396) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D055172" #### Added -- [pulmonary venule](http://purl.obolibrary.org/obo/UBERON_8600024) [date](http://purl.org/dc/terms/date) "2023-10-24T11:26:27Z"^^[dateTime](http://www.w3.org/2001/XMLSchema#dateTime) +- [vomer](http://purl.obolibrary.org/obo/UBERON_0002396) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D055172" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + + - [author_id](https://w3id.org/sssom/author_id) [0000-0001-9439-5346](https://orcid.org/0000-0001-9439-5346) -- [pulmonary venule](http://purl.obolibrary.org/obo/UBERON_8600024) [label](http://www.w3.org/2000/01/rdf-schema#label) "pulmonary venule" + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" -- [pulmonary venule](http://purl.obolibrary.org/obo/UBERON_8600024) [definition](http://purl.obolibrary.org/obo/IAO_0000115) "A venule that is part of a lung and drains oxygenated blood from pulmonary capillaries. A pulmonary venule merges into a pulmonary vein branch that runs in the pulmonary interlobular septa." - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:30247823" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "PMID:22283705" +### vomeronasal organ `http://purl.obolibrary.org/obo/UBERON_0002255` +#### Removed +- [vomeronasal organ](http://purl.obolibrary.org/obo/UBERON_0002255) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "organum vomeronasale" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Vomeronasal_organ" -- [pulmonary venule](http://purl.obolibrary.org/obo/UBERON_8600024) [has_obo_namespace](http://www.geneontology.org/formats/oboInOwl#hasOBONamespace) "uberon" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) -- [pulmonary venule](http://purl.obolibrary.org/obo/UBERON_8600024) [contributor](http://purl.org/dc/terms/contributor) [0000-0001-6677-8489](https://orcid.org/0000-0001-6677-8489) +- [vomeronasal organ](http://purl.obolibrary.org/obo/UBERON_0002255) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "organon vomeronasale" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) -- [pulmonary venule](http://purl.obolibrary.org/obo/UBERON_8600024) [id](http://www.geneontology.org/formats/oboInOwl#id) "UBERON:8600024" +#### Added +- [vomeronasal organ](http://purl.obolibrary.org/obo/UBERON_0002255) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "organon vomeronasale" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) -- Class: [pulmonary venule](http://purl.obolibrary.org/obo/UBERON_8600024) +- [vomeronasal organ](http://purl.obolibrary.org/obo/UBERON_0002255) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "organum vomeronasale" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) -- [pulmonary venule](http://purl.obolibrary.org/obo/UBERON_8600024) EquivalentTo [venule](http://purl.obolibrary.org/obo/UBERON_0001979) and ([part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [lung](http://purl.obolibrary.org/obo/UBERON_0002048)) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Vomeronasal_organ" -- [pulmonary venule](http://purl.obolibrary.org/obo/UBERON_8600024) SubClassOf [thoracic vein](http://purl.obolibrary.org/obo/UBERON_0005194) -- [pulmonary venule](http://purl.obolibrary.org/obo/UBERON_8600024) SubClassOf [drains](http://purl.obolibrary.org/obo/RO_0002179) some [pulmonary capillary](http://purl.obolibrary.org/obo/UBERON_0016405) +### white adipose tissue `http://purl.obolibrary.org/obo/UBERON_0001347` +#### Removed +- [white adipose tissue](http://purl.obolibrary.org/obo/UBERON_0001347) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D052436" -- [pulmonary venule](http://purl.obolibrary.org/obo/UBERON_8600024) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [pulmonary venous system](http://purl.obolibrary.org/obo/UBERON_0013127) +- [white adipose tissue](http://purl.obolibrary.org/obo/UBERON_0001347) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "textus adiposus albus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:White_adipose_tissue" -- [pulmonary venule](http://purl.obolibrary.org/obo/UBERON_8600024) SubClassOf [connected to](http://purl.obolibrary.org/obo/RO_0002170) some [pulmonary vein](http://purl.obolibrary.org/obo/UBERON_0002016) + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) -- [pulmonary venule](http://purl.obolibrary.org/obo/UBERON_8600024) SubClassOf [lung blood vessel](http://purl.obolibrary.org/obo/UBERON_0003512) +#### Added +- [white adipose tissue](http://purl.obolibrary.org/obo/UBERON_0001347) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D052436" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) -- [pulmonary venule](http://purl.obolibrary.org/obo/UBERON_8600024) SubClassOf [respiratory system venule](http://purl.obolibrary.org/obo/UBERON_0003494) + - [author_id](https://w3id.org/sssom/author_id) [0000-0001-9439-5346](https://orcid.org/0000-0001-9439-5346) + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" -### renal afferent arteriole `http://purl.obolibrary.org/obo/UBERON_0004639` -#### Removed -- [renal afferent arteriole](http://purl.obolibrary.org/obo/UBERON_0004639) SubClassOf [branching part of](http://purl.obolibrary.org/obo/RO_0002380) some [interlobular artery](http://purl.obolibrary.org/obo/UBERON_0004723) +- [white adipose tissue](http://purl.obolibrary.org/obo/UBERON_0001347) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "textus adiposus albus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) -#### Added -- [renal afferent arteriole](http://purl.obolibrary.org/obo/UBERON_0004639) SubClassOf [connecting branch of](http://purl.obolibrary.org/obo/RO_0002252) some [interlobular artery](http://purl.obolibrary.org/obo/UBERON_0004723) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:White_adipose_tissue" -### right eye `http://purl.obolibrary.org/obo/UBERON_0004549` +### white matter `http://purl.obolibrary.org/obo/UBERON_0002316` #### Removed -- [right eye](http://purl.obolibrary.org/obo/UBERON_0004549) [depiction](http://xmlns.com/foaf/0.1/depiction) "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Eye_R.glb"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) +- [white matter](http://purl.obolibrary.org/obo/UBERON_0002316) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "substantia alba" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:White_matter" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) -- [right eye](http://purl.obolibrary.org/obo/UBERON_0004549) [depiction](http://xmlns.com/foaf/0.1/depiction) "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Eye_R.glb"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) +- [white matter](http://purl.obolibrary.org/obo/UBERON_0002316) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D066127" +#### Added +- [white matter](http://purl.obolibrary.org/obo/UBERON_0002316) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "MESH:D066127" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) + - [author_id](https://w3id.org/sssom/author_id) [0000-0001-9439-5346](https://orcid.org/0000-0001-9439-5346) -### right lung `http://purl.obolibrary.org/obo/UBERON_0002167` -#### Removed -- [right lung](http://purl.obolibrary.org/obo/UBERON_0002167) [depiction](http://xmlns.com/foaf/0.1/depiction) "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Lung.glb"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" -- [right lung](http://purl.obolibrary.org/obo/UBERON_0002167) [depiction](http://xmlns.com/foaf/0.1/depiction) "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Lung.glb"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) +- [white matter](http://purl.obolibrary.org/obo/UBERON_0002316) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "substantia alba" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:White_matter" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) -### segmental bronchus `http://purl.obolibrary.org/obo/UBERON_0002184` +### white matter lamina of cerebellum `http://purl.obolibrary.org/obo/UBERON_0014540` #### Removed -- [segmental bronchus](http://purl.obolibrary.org/obo/UBERON_0002184) [depiction](http://xmlns.com/foaf/0.1/depiction) "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Lung.glb"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) +- [white matter lamina of cerebellum](http://purl.obolibrary.org/obo/UBERON_0014540) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "isthmus cinguli" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:163" -- [segmental bronchus](http://purl.obolibrary.org/obo/UBERON_0002184) [depiction](http://xmlns.com/foaf/0.1/depiction) "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Lung.glb"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) +- [white matter lamina of cerebellum](http://purl.obolibrary.org/obo/UBERON_0014540) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "isthmus gyri cinguli" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:163" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) -### skeletal muscle organ `http://purl.obolibrary.org/obo/UBERON_0014892` -#### Removed -- [skeletal muscle organ](http://purl.obolibrary.org/obo/UBERON_0014892) [label](http://www.w3.org/2000/01/rdf-schema#label) "skeletal muscle organ" +- [white matter lamina of cerebellum](http://purl.obolibrary.org/obo/UBERON_0014540) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "isthmus gyri cingulatus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:163" -#### Added -- [skeletal muscle organ](http://purl.obolibrary.org/obo/UBERON_0014892) [label](http://www.w3.org/2000/01/rdf-schema#label) "skeletal muscle organ, vertebrate" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) -- [skeletal muscle organ](http://purl.obolibrary.org/obo/UBERON_0014892) SubClassOf [only in taxon](http://purl.obolibrary.org/obo/RO_0002160) some [Vertebrata ](http://purl.obolibrary.org/obo/NCBITaxon_7742) +- [white matter lamina of cerebellum](http://purl.obolibrary.org/obo/UBERON_0014540) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "isthmus of gyrus fornicatus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:163" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) -### skin bony tubercle `http://purl.obolibrary.org/obo/UBERON_0017163` -#### Removed -- [skin bony tubercle](http://purl.obolibrary.org/obo/UBERON_0017163) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "bony tubercles" - - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "UBERONTEMP:3b77fb04-1e62-43af-a84b-5d5eb7388525" +- [white matter lamina of cerebellum](http://purl.obolibrary.org/obo/UBERON_0014540) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "isthmus-2" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:163" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [plural form](http://purl.obolibrary.org/obo/OMO_0003004) + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) #### Added -- [skin bony tubercle](http://purl.obolibrary.org/obo/UBERON_0017163) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "bony tubercles" - - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [plural form](http://purl.obolibrary.org/obo/OMO_0003004) +- [white matter lamina of cerebellum](http://purl.obolibrary.org/obo/UBERON_0014540) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "isthmus gyri cinguli" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:163" -### skin of body `http://purl.obolibrary.org/obo/UBERON_0002097` -#### Removed -- [skin of body](http://purl.obolibrary.org/obo/UBERON_0002097) [depiction](http://xmlns.com/foaf/0.1/depiction) "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Skin.glb"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) +- [white matter lamina of cerebellum](http://purl.obolibrary.org/obo/UBERON_0014540) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "isthmus-2" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:163" +- [white matter lamina of cerebellum](http://purl.obolibrary.org/obo/UBERON_0014540) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "isthmus gyri cingulatus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) -### skin of lip `http://purl.obolibrary.org/obo/UBERON_0001458` -#### Removed -- [skin of lip](http://purl.obolibrary.org/obo/UBERON_0001458) SubClassOf [skin of head](http://purl.obolibrary.org/obo/UBERON_0001084) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:163" -#### Added -- [skin of lip](http://purl.obolibrary.org/obo/UBERON_0001458) SubClassOf [zone of skin](http://purl.obolibrary.org/obo/UBERON_0000014) +- [white matter lamina of cerebellum](http://purl.obolibrary.org/obo/UBERON_0014540) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "isthmus of gyrus fornicatus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:163" -### skull `http://purl.obolibrary.org/obo/UBERON_0003129` -#### Removed -- [skull](http://purl.obolibrary.org/obo/UBERON_0003129) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [NCBITaxon_7762](http://purl.obolibrary.org/obo/NCBITaxon_7762) +- [white matter lamina of cerebellum](http://purl.obolibrary.org/obo/UBERON_0014540) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "isthmus cinguli" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NeuroNames:163" -### spleen trabecular artery `http://purl.obolibrary.org/obo/UBERON_0010399` +### white matter of spinal cord `http://purl.obolibrary.org/obo/UBERON_0002318` #### Removed -- [spleen trabecular artery](http://purl.obolibrary.org/obo/UBERON_0010399) SubClassOf [systemic artery](http://purl.obolibrary.org/obo/UBERON_0004573) +- [white matter of spinal cord](http://purl.obolibrary.org/obo/UBERON_0002318) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "substantia alba medullae spinalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:83945" + + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) -- [spleen trabecular artery](http://purl.obolibrary.org/obo/UBERON_0010399) SubClassOf [branching part of](http://purl.obolibrary.org/obo/RO_0002380) some [splenic artery](http://purl.obolibrary.org/obo/UBERON_0001194) - - [source](http://www.geneontology.org/formats/oboInOwl#source) "MP" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" #### Added -- [spleen trabecular artery](http://purl.obolibrary.org/obo/UBERON_0010399) SubClassOf [artery](http://purl.obolibrary.org/obo/UBERON_0001637) +- [white matter of spinal cord](http://purl.obolibrary.org/obo/UBERON_0002318) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "substantia alba medullae spinalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) -- [spleen trabecular artery](http://purl.obolibrary.org/obo/UBERON_0010399) SubClassOf [connecting branch of](http://purl.obolibrary.org/obo/RO_0002252) some [splenic artery](http://purl.obolibrary.org/obo/UBERON_0001194) - - [source](http://www.geneontology.org/formats/oboInOwl#source) "MP" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:83945" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" -### splenic artery `http://purl.obolibrary.org/obo/UBERON_0001194` -#### Removed -- [splenic artery](http://purl.obolibrary.org/obo/UBERON_0001194) SubClassOf [branching part of](http://purl.obolibrary.org/obo/RO_0002380) some [celiac artery](http://purl.obolibrary.org/obo/UBERON_0001640) -- [splenic artery](http://purl.obolibrary.org/obo/UBERON_0001194) SubClassOf [systemic artery](http://purl.obolibrary.org/obo/UBERON_0004573) +### white pulp of spleen `http://purl.obolibrary.org/obo/UBERON_0001959` +#### Removed +- [white pulp of spleen](http://purl.obolibrary.org/obo/UBERON_0001959) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "noduli lymphoidei splenici" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) -#### Added -- [splenic artery](http://purl.obolibrary.org/obo/UBERON_0001194) SubClassOf [artery](http://purl.obolibrary.org/obo/UBERON_0001637) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:White_pulp" -- [splenic artery](http://purl.obolibrary.org/obo/UBERON_0001194) SubClassOf [connecting branch of](http://purl.obolibrary.org/obo/RO_0002252) some [celiac artery](http://purl.obolibrary.org/obo/UBERON_0001640) +- [white pulp of spleen](http://purl.obolibrary.org/obo/UBERON_0001959) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pulpa alba" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:62805" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) -### superior vesical artery `http://purl.obolibrary.org/obo/UBERON_0001312` + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" #### Added -- [superior vesical artery](http://purl.obolibrary.org/obo/UBERON_0001312) SubClassOf [connecting branch of](http://purl.obolibrary.org/obo/RO_0002252) some [umbilical artery](http://purl.obolibrary.org/obo/UBERON_0001310) - +- [white pulp of spleen](http://purl.obolibrary.org/obo/UBERON_0001959) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "noduli lymphoidei splenici" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) -### thymic artery `http://purl.obolibrary.org/obo/UBERON_0018243` -#### Removed -- [thymic artery](http://purl.obolibrary.org/obo/UBERON_0018243) SubClassOf [branching part of](http://purl.obolibrary.org/obo/RO_0002380) some [internal thoracic artery](http://purl.obolibrary.org/obo/UBERON_0002456) - - [source](http://www.geneontology.org/formats/oboInOwl#source) "FMA" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:White_pulp" -- [thymic artery](http://purl.obolibrary.org/obo/UBERON_0018243) SubClassOf [systemic artery](http://purl.obolibrary.org/obo/UBERON_0004573) +- [white pulp of spleen](http://purl.obolibrary.org/obo/UBERON_0001959) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "pulpa alba" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) -#### Added -- [thymic artery](http://purl.obolibrary.org/obo/UBERON_0018243) SubClassOf [connecting branch of](http://purl.obolibrary.org/obo/RO_0002252) some [internal thoracic artery](http://purl.obolibrary.org/obo/UBERON_0002456) - - [source](http://www.geneontology.org/formats/oboInOwl#source) "FMA" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:62805" -- [thymic artery](http://purl.obolibrary.org/obo/UBERON_0018243) SubClassOf [artery](http://purl.obolibrary.org/obo/UBERON_0001637) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" -### tongue muscle `http://purl.obolibrary.org/obo/UBERON_0000378` +### yellow bone marrow `http://purl.obolibrary.org/obo/UBERON_0000332` #### Removed -- [tongue muscle](http://purl.obolibrary.org/obo/UBERON_0000378) SubClassOf [craniocervical muscle](http://purl.obolibrary.org/obo/UBERON_0010959) - -#### Added -- [tongue muscle](http://purl.obolibrary.org/obo/UBERON_0000378) SubClassOf [skeletal muscle organ](http://purl.obolibrary.org/obo/UBERON_0014892) - - [source](http://www.geneontology.org/formats/oboInOwl#source) "FEED:rd" +- [yellow bone marrow](http://purl.obolibrary.org/obo/UBERON_0000332) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "medulla ossium flava" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0000635" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) -### trachea `http://purl.obolibrary.org/obo/UBERON_0003126` -#### Removed -- [trachea](http://purl.obolibrary.org/obo/UBERON_0003126) [depiction](http://xmlns.com/foaf/0.1/depiction) "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Lung.glb"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) +#### Added +- [yellow bone marrow](http://purl.obolibrary.org/obo/UBERON_0000332) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "medulla ossium flava" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "BTO:0000635" -### trachea cartilage `http://purl.obolibrary.org/obo/UBERON_0003604` +### yolk sac `http://purl.obolibrary.org/obo/UBERON_0001040` #### Removed -- [trachea cartilage](http://purl.obolibrary.org/obo/UBERON_0003604) [depiction](http://xmlns.com/foaf/0.1/depiction) "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Lung.glb"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) - -- [trachea cartilage](http://purl.obolibrary.org/obo/UBERON_0003604) [depiction](http://xmlns.com/foaf/0.1/depiction) "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Lung.glb"^^[anyURI](http://www.w3.org/2001/XMLSchema#anyURI) - +- [yolk sac](http://purl.obolibrary.org/obo/UBERON_0001040) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "saccus vitellinus" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Yolk_sac" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) -### umbrella cell of urothelium `http://purl.obolibrary.org/obo/CL_4030056` -#### Removed -- [umbrella cell of urothelium](http://purl.obolibrary.org/obo/CL_4030056) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606) - -- [umbrella cell of urothelium](http://purl.obolibrary.org/obo/CL_4030056) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [human_reference_atlas](http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas) +- [yolk sac](http://purl.obolibrary.org/obo/UBERON_0001040) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vesicula umbilicalis" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Yolk_sac" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) +#### Added +- [yolk sac](http://purl.obolibrary.org/obo/UBERON_0001040) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "vesicula umbilicalis" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) -### ureter smooth muscle cell `http://purl.obolibrary.org/obo/CL_1000979` -#### Removed -- [ureter smooth muscle cell](http://purl.obolibrary.org/obo/CL_1000979) [in_subset](http://www.geneontology.org/formats/oboInOwl#inSubset) [human_reference_atlas](http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Yolk_sac" -- [ureter smooth muscle cell](http://purl.obolibrary.org/obo/CL_1000979) [present_in_taxon](http://purl.obolibrary.org/obo/RO_0002175) [Homo sapiens](http://purl.obolibrary.org/obo/NCBITaxon_9606) +- [yolk sac](http://purl.obolibrary.org/obo/UBERON_0001040) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "saccus vitellinus" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Yolk_sac" -### ureteric segment of renal artery `http://purl.obolibrary.org/obo/UBERON_0003468` +### zygomaticotemporal nerve `http://purl.obolibrary.org/obo/UBERON_0036264` #### Removed -- [ureteric segment of renal artery](http://purl.obolibrary.org/obo/UBERON_0003468) SubClassOf [branching part of](http://purl.obolibrary.org/obo/RO_0002380) some [renal artery](http://purl.obolibrary.org/obo/UBERON_0001184) - - [source](http://www.geneontology.org/formats/oboInOwl#source) "FMA" +- [zygomaticotemporal nerve](http://purl.obolibrary.org/obo/UBERON_0036264) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ramus zygomaticotemporalis nervus zygomatici" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) -#### Added -- [ureteric segment of renal artery](http://purl.obolibrary.org/obo/UBERON_0003468) SubClassOf [connecting branch of](http://purl.obolibrary.org/obo/RO_0002252) some [renal artery](http://purl.obolibrary.org/obo/UBERON_0001184) - - [source](http://www.geneontology.org/formats/oboInOwl#source) "FMA" - - -### vertebra `http://purl.obolibrary.org/obo/UBERON_0002412` + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" #### Added -- [vertebra](http://purl.obolibrary.org/obo/UBERON_0002412) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [vertebral column](http://purl.obolibrary.org/obo/UBERON_0001130) +- [zygomaticotemporal nerve](http://purl.obolibrary.org/obo/UBERON_0036264) [has exact synonym](http://www.geneontology.org/formats/oboInOwl#hasExactSynonym) "ramus zygomaticotemporalis nervus zygomatici" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "FMA:TA" -### vertebral element `http://purl.obolibrary.org/obo/UBERON_0010913` + +### zygote stage `http://purl.obolibrary.org/obo/UBERON_0000106` #### Removed -- [vertebral element](http://purl.obolibrary.org/obo/UBERON_0010913) SubClassOf [part_of](http://purl.obolibrary.org/obo/BFO_0000050) some [vertebral column](http://purl.obolibrary.org/obo/UBERON_0001130) - - [source](http://www.geneontology.org/formats/oboInOwl#source) "VSAO" +- [zygote stage](http://purl.obolibrary.org/obo/UBERON_0000106) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IDOMAL:0000302" + - [contributor](http://purl.org/dc/terms/contributor) "https://orcid.org/0000-0003-4423-4370" +- [zygote stage](http://purl.obolibrary.org/obo/UBERON_0000106) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "zygotum" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Zygote" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [LATIN](http://purl.obolibrary.org/obo/uberon/core#LATIN) -### vitelline artery `http://purl.obolibrary.org/obo/UBERON_0006002` -#### Removed -- [vitelline artery](http://purl.obolibrary.org/obo/UBERON_0006002) SubClassOf [trunk blood vessel](http://purl.obolibrary.org/obo/UBERON_0003513) +#### Added +- [zygote stage](http://purl.obolibrary.org/obo/UBERON_0000106) [has_related_synonym](http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym) "zygotum" + - [has_synonym_type](http://www.geneontology.org/formats/oboInOwl#hasSynonymType) [OMO_0003011](http://purl.obolibrary.org/obo/OMO_0003011) -- [vitelline artery](http://purl.obolibrary.org/obo/UBERON_0006002) SubClassOf [branching part of](http://purl.obolibrary.org/obo/RO_0002380) some [dorsal aorta](http://purl.obolibrary.org/obo/UBERON_0005805) - - [notes](http://www.geneontology.org/formats/oboInOwl#notes) "ventral branch" + - [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "Wikipedia:Zygote" -- [vitelline artery](http://purl.obolibrary.org/obo/UBERON_0006002) SubClassOf [systemic artery](http://purl.obolibrary.org/obo/UBERON_0004573) +- [zygote stage](http://purl.obolibrary.org/obo/UBERON_0000106) [database_cross_reference](http://www.geneontology.org/formats/oboInOwl#hasDbXref) "IDOMAL:0000302" + - [mapping_justification](https://w3id.org/sssom/mapping_justification) [ManualMappingCuration](https://w3id.org/semapv/vocab/ManualMappingCuration) -#### Added -- [vitelline artery](http://purl.obolibrary.org/obo/UBERON_0006002) SubClassOf [connecting branch of](http://purl.obolibrary.org/obo/RO_0002252) some [dorsal aorta](http://purl.obolibrary.org/obo/UBERON_0005805) - - [notes](http://www.geneontology.org/formats/oboInOwl#notes) "ventral branch" + - [mapping_provider](https://w3id.org/sssom/mapping_provider) "https://github.com/biopragmatics/biomappings" -- [vitelline artery](http://purl.obolibrary.org/obo/UBERON_0006002) SubClassOf [artery](http://purl.obolibrary.org/obo/UBERON_0001637) + - [author_id](https://w3id.org/sssom/author_id) [0000-0003-4423-4370](https://orcid.org/0000-0003-4423-4370) diff --git a/src/ontology/reports/cl-edit.owl-obo-report.tsv b/src/ontology/reports/cl-edit.owl-obo-report.tsv index 355548e8f..72c59aee6 100644 --- a/src/ontology/reports/cl-edit.owl-obo-report.tsv +++ b/src/ontology/reports/cl-edit.owl-obo-report.tsv @@ -299,6 +299,7 @@ WARN missing_definition oboInOwl:hasSynonymType IAO:0000115 WARN missing_definition oboInOwl:inSubset IAO:0000115 WARN missing_definition oboInOwl:shorthand IAO:0000115 WARN missing_obsolete_label CL:0000736 rdfs:label embryonic gland hemocyte +WARN missing_subset_declaration obo:cl#cellxgene_subset rdfs:subPropertyOf WARN missing_synonymtype_declaration OMO:0003000 rdfs:subPropertyOf WARN missing_synonymtype_declaration OMO:0003004 rdfs:subPropertyOf WARN missing_synonymtype_declaration obo:uberon/core#MISSPELLING rdfs:subPropertyOf @@ -760,6 +761,7 @@ INFO missing_superclass CL:4023016 rdfs:subClassOf INFO missing_superclass CL:4023017 rdfs:subClassOf INFO missing_superclass CL:4023018 rdfs:subClassOf INFO missing_superclass CL:4023019 rdfs:subClassOf +INFO missing_superclass CL:4023035 rdfs:subClassOf INFO missing_superclass CL:4023038 rdfs:subClassOf INFO missing_superclass CL:4023039 rdfs:subClassOf INFO missing_superclass CL:4023043 rdfs:subClassOf @@ -864,4 +866,5 @@ INFO missing_superclass CL:4033052 rdfs:subClassOf INFO missing_superclass CL:4033054 rdfs:subClassOf INFO missing_superclass CL:4033055 rdfs:subClassOf INFO missing_superclass CL:4033061 rdfs:subClassOf +INFO missing_superclass CL:4033064 rdfs:subClassOf INFO missing_superclass CL:4040004 rdfs:subClassOf diff --git a/src/ontology/subsets/blood_and_immune_upper_slim.json b/src/ontology/subsets/blood_and_immune_upper_slim.json index a642004a5..f2b3e3a5d 100644 --- a/src/ontology/subsets/blood_and_immune_upper_slim.json +++ b/src/ontology/subsets/blood_and_immune_upper_slim.json @@ -4,9 +4,9 @@ "meta" : { "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2002/07/owl#versionInfo", - "val" : "2024-01-04" + "val" : "2024-02-13" } ], - "version" : "http://purl.obolibrary.org/obo/cl/releases/2024-01-04/subsets/blood_and_immune_upper_slim.owl" + "version" : "http://purl.obolibrary.org/obo/cl/releases/2024-02-13/subsets/blood_and_immune_upper_slim.owl" }, "nodes" : [ { "id" : "http://purl.obolibrary.org/obo/BFO_0000002", @@ -731,7 +731,7 @@ "xrefs" : [ "CARO:mah" ] }, "comments" : [ "The definition of cell is intended to represent all cells, and thus a cell is defined as a material entity and not an anatomical structure, which implies that it is part of an organism (or the entirety of one)." ], - "subsets" : [ "http://purl.obolibrary.org/obo/ubprop#_upper_level" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/ubprop#_upper_level" ], "xrefs" : [ { "val" : "CALOHA:TS-2035" }, { @@ -772,7 +772,7 @@ "xrefs" : [ "GOC:tfm", "MESH:D013234" ] }, "comments" : [ "This term applies to metazoan. For plant stem cells, consider using PO:0004011 ‘initial cell’ or its parent PO:0004010 ‘meristematic cell’." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "animal stem cell" @@ -797,7 +797,7 @@ "xrefs" : [ "GOC:add", "GOC:dsd", "GOC:tfm", "PMID:19022770", "http://en.wikipedia.org/wiki/Hematopoietic_stem_cell" ] }, "comments" : [ "Markers differ between species, and two sets of markers have been described for mice. HSCs are reportedly CD34-positive, CD45-positive, CD48-negative, CD150-positive, CD133-positive, and CD244-negative." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "blood forming stem cell" @@ -837,7 +837,7 @@ "val" : "A progenitor cell committed to the erythroid lineage.", "xrefs" : [ "GOC:add", "ISBN:0721601464" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003000", "pred" : "hasRelatedSynonym", @@ -929,7 +929,7 @@ "xrefs" : [ "GOC:add", "ISBN:0878932437", "MESH:D023461" ] }, "comments" : [ "This cell type is intended to be compatible with any vertebrate common myeloid progenitor. For mammalian CMP known to be CD34-positive, please use the term 'common myeloid progenitor, CD34-positive' (CL_0001059)." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "common myeloid precursor" @@ -983,7 +983,7 @@ "xrefs" : [ "GOC:add", "GOC:dsd", "GOC:tfm", "MESH:D055015", "PMID:16647566", "http://en.wikipedia.org/wiki/Megakaryocyte-erythroid_progenitor_cell" ] }, "comments" : [ "MEPs are reportedly CD19-negative, CD34-negative, CD45RA-negative, CD110-positive, CD117-positive, and SCA1-negative and reportedly express the transcription factors GATA-1 and NF-E2." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "CFU-EM" @@ -1021,7 +1021,7 @@ "xrefs" : [ "GOC:add", "GOC:dsd", "GOC:tfm", "PMID:10407577", "PMID:16551251" ] }, "comments" : [ "CLP are CD7-positive, CD10-positive, CD19-negative, CD34-positive, CD45RA-positive, CD79a-negative, CD127-positive, AA4.1-positive, RAG-negative, Sca-1-low, sIgM-negative, sIgD-negative, TdT-negative, Vpre-B-negative, and pre-BCR-negative. Expression of transcription factors include E2A-positive, EBF-positive, Ikaros-negative, PU.1-negative, and Pax5-negative." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "common lymphocyte precursor" @@ -1086,6 +1086,7 @@ "xrefs" : [ "SANBI:mhl" ] }, "comments" : [ "define using PATO mulit-potent or oligopotent?" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "blast cell" @@ -1127,7 +1128,7 @@ "xrefs" : [ "ISBN:0517223651", "MESH:D005347", "http://en.wikipedia.org/wiki/Fibroblast" ] }, "comments" : [ "These cells may be vimentin-positive, fibronectin-positive, fsp1-positive, MMP-1-positive, collagen I-positive, collagen III-positive, and alpha-SMA-negative." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { "val" : "BTO:0000452" }, { @@ -1153,7 +1154,7 @@ "val" : "A cell that is usually found in a two-dimensional sheet with a free surface. The cell has a cytoskeleton that allows for tight cell to cell contact and for cell polarity where apical part is directed towards the lumen and the basal part to the basal lamina.", "xrefs" : [ "FB:ma", "GOC:tfm", "MESH:D004847" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "epitheliocyte" @@ -1188,7 +1189,7 @@ "val" : "An endothelial cell that lines the vasculature.", "xrefs" : [ "GOC:tfm" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cuboidal endothelial cell of vascular tree" @@ -1203,6 +1204,7 @@ "lbl" : "squamous epithelial cell", "type" : "CLASS", "meta" : { + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "CALOHA:TS-1249" } ] @@ -1226,7 +1228,7 @@ "val" : "A cell found predominately in the blood.", "xrefs" : [ "GOC:add", "GOC:tfm" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim" ], "xrefs" : [ { "val" : "FMA:62844" }, { @@ -1242,7 +1244,7 @@ "val" : "A type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex.", "xrefs" : [ "GOC:add", "GOC:tfm", "ISBN:0781735149" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "T lymphocyte" @@ -1285,6 +1287,7 @@ "xrefs" : [ "GOC:add", "GOC:tfm", "GO_REF:0000031", "ISBN:0781735149", "PMID:10428500", "PMID:15055519", "PMID:17380158" ] }, "comments" : [ "Morphology: Highly vesicular; markers: Surface: RANK, cFMS (MCSF receptor); Secreted: cathepsin K and TRAP (tartate resistant acid phosphatase); transcription factors: PU.1, cFOS, MITF, NFkB (p52); role or process: tissue remodelling: bone resorption; lineage: hematopoietic, myeloid." ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "chondroclast" @@ -1308,7 +1311,7 @@ "val" : "A leukocyte with abundant granules in the cytoplasm.", "xrefs" : [ "GOC:amm", "GOC:tfm", "MESH:D006098", "http://en.wikipedia.org/wiki/Granulocyte" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "granular leucocyte" @@ -1343,7 +1346,7 @@ "xrefs" : [ "GOC:add", "GOC:dsd", "GOC:tfm", "ISBN:068340007X", "MESH:D008407", "PMCID:PMC1312421", "PMCID:PMC2855166", "PMID:15153310", "PMID:16455980", "PMID:19671378", "PMID:212366338", "PMID:9354811" ] }, "comments" : [ "Mast cells are generally integrin beta-7-negative and positive for TLR2, TLR3, TLR4, TLR5, TLR7, TLR9, C3aR, C5aR, CR3, CR4, VEGF, FGF2, and renin. They can express MHC Class I and II on their surface. Activated murine mast cells (IgE+Antigen) were capable of expressing the following co-stimulatory molecules: CD95 (Fas), CD120b, CD137 (4-1BB), CD153 (CD30L), CD154 (CD40L), GITR, ICOSL, OX40L, PD-L1, and PD-L2. Note that there was some mouse strain variation. Mast cells have also been demonstrated to produce bFGF, CCL2, CCL4, CCL5, CCL11, CCL20, CXCL2, CXCL8, CXCL10, GM-CSF, IFN-gamma, IL-1, IL-2, IL-3, IL-8, IL-10, IL-11, IL-12, IL-13, IL-16, IL-25, IL-18, MIP-1, prostaglandin D2, SCF, TGF-beta, TNF-alpha, TSLP, VEGF, and XCL1. They express the transcription factors Transcription factors AP-1, GATA1, MITF, Notch2, PIAS3, PU.1, and STAT5." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "histaminocyte" @@ -1381,7 +1384,7 @@ "val" : "A vertebrate phagocyte with a single nucleus.", "xrefs" : [ "GOC:add", "GOC:tfm", "ISBN:0781735149" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { "val" : "BTO:0001433" } ], @@ -1400,7 +1403,7 @@ "xrefs" : [ "GOC:tfm", "MESH:D042783", "PMID:21275341", "http://en.wikipedia.org/wiki/Endothelial_cell", "https://sourceforge.net/tracker/?func=detail&atid=440764&aid=3364936&group_id=36855" ] }, "comments" : [ "From FMA: 9.07.2001: Endothelial cell has always been classified as a kind of epithelial cell, specifically a squamous cell but that is not true. First, endothelial cell can either be squamous or cuboidal (e.g. high-endothelial cell) and secondly, it has different embryological derivation (mesodermal) than a true epithelial cell (ectodermal and endodermal). The basis for present classification is the fact that it comprises the outermost layer or lining of anatomical structures (location-based) but a better structural basis for the differentia is the cytoskeleton of the cell. Endothelial cell has vimentin filaments while an epithelial cell has keratin filaments. [Onard]." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "endotheliocyte" @@ -1441,6 +1444,7 @@ "xrefs" : [ "FB:ma", "GOC:dsd", "PMCID:PMC2613570", "PMID:10102814", "PMID:16923606", "PMID:17986482", "PMID:19960544", "http://en.wikipedia.org/wiki/Mesenchymal_stem_cell", "http://www.copewithcytokines.de/cope.cgi?key=mesenchymal%20stem%20cells" ] }, "comments" : [ "Many but not all mesenchymal cells derive from the mesoderm. MSCs are reportedly CD3-negative, CD4-negative, CD5-negative, CD8-negative, CD11a-negative, CD11b-negative, CD14-negative, CD19-negative, CD29-positive, CD31-negative, CD34-negative, CD38-negative, CD40-negative, CD44-positive, CD45-negative, CD49-positive, CD54-positive, CD66b-negative, CD79a-negative, CD80-negative, CD102-positive, CD106-positive, CD117-positive, CD121a-positive, CD121b-positive, CD123-positive, CD124-positive, CD133-negative, CD146-positive, CD166-positive, CD271-positive, B220-negative, Gr1-negative, MHCI-positive, MHCII-negative, SSEA4-negative, sca1-positive, Ter119-negative, and glycophorin A-negative. Cultured MSCs are capable of producing stem cell factor, IL7, IL8, IL11, TGF-beta, cofilin, galectin-1, laminin-receptor 1, cyclophilin A, and MMP-2." ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "bone marrow stromal cells" @@ -1510,7 +1514,7 @@ "xrefs" : [ "GOC:add", "ISBN:0781735149" ] }, "comments" : [ "Note change of name; nearly all somatic cells can present antigens to T cells via MHC Class I complexes leading to effector responses, but professional antigen presenting cells constitutively express MHC Class II as well as costimulatory molecules, and thus can initiate immune responses via T cells." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003000", "pred" : "hasRelatedSynonym", @@ -1526,6 +1530,7 @@ "val" : "A cell that specializes in controlled release of one or more substances.", "xrefs" : [ "GOC:tfm", "ISBN:0721662544" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "BTO:0003659" }, { @@ -1540,7 +1545,8 @@ "definition" : { "val" : "A cell whose primary function is to shorten.", "xrefs" : [ "FB:ma" ] - } + }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000187", @@ -1551,6 +1557,7 @@ "val" : "A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns.", "xrefs" : [ "MESH:D032342" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "muscle fiber" @@ -1646,6 +1653,7 @@ "val" : "A cell of the middle germ layer of the embryo.", "xrefs" : [ "MESH:D008648" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "mesoblast" @@ -1735,7 +1743,7 @@ "val" : "A red blood cell. In mammals, mature erythrocytes are biconcave disks containing hemoglobin whose function is to transport oxygen.", "xrefs" : [ "GOC:tfm", "MESH:D004912" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "RBC" @@ -1765,7 +1773,7 @@ "xrefs" : [ "GOC:add", "GOC:dsd", "GOC:tfm", "MESH:D001792", "PMID:11110672", "PMID:16987572", "PMID:17204662", "PMID:17479180", "PMID:20414831", "http://en.wikipedia.org/wiki/Platelet" ] }, "comments" : [ "Platelets are reportedly CCR1-positive, CCR2-negative, CCR3-positive, CCR4-positive, CCR5-negative, CCR6-negative, CCR7-negative, CCR8-negative, CCR9-negative, CCR10-negative, CD16-positive, CD23-positive, CD32-positive, CD40-positive, CD41-positive CD42-positive, CD61-positive, CD62P-positive, CD64-positive, CD89-positive, CD102-positive, CD147-positive (activated platelets), CD154-positive (activated platelets), CD162-positive, CD209, CD282-positive, CD284-positive, CD289-positive, CD181-negative, CD182-negative, CD183-negative, CD184-positive, CLEC2-positive, GPVI-positive, JAMC-positive, PAR1-positive, PAR2-negative, PAR3-positive, PAR4-positive, TSP1-positive, and TXA2R-positive. Platelets can reportedly produce CCL2, CCL3, CCL5, CCL7, CCL17, CD40L, CXCL1, CXCL4, CXCL4L1, CXCL5, CXCL7, CXCL8, CXCL12, EGF, factor V, factor VII, factor XI, factor XIII, bFGF, histamine, IGF-1, IL-1beta, PAI-1, PDGF, plasminogen, protein S, serotonin, TGF-beta, TFPI, VEGF, and vWF." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "anucleate thrombocyte" @@ -1797,6 +1805,7 @@ "val" : "Any cell capable of ingesting particulate matter via phagocytosis.", "xrefs" : [ "GOC:add", "ISBN:0721601464" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "BTO:0001044" }, { @@ -1815,7 +1824,7 @@ "xrefs" : [ "GOC:add", "GOC:tfm", "GO_REF:0000031", "PMID:16213494", "PMID:1919437" ] }, "comments" : [ "Morphology: Diameter 30_M-80 _M, abundant cytoplasm, low N/C ratio, eccentric nucleus. Irregular shape with pseudopods, highly adhesive. Contain vacuoles and phagosomes, may contain azurophilic granules; markers: Mouse & Human: CD68, in most cases CD11b. Mouse: in most cases F4/80+; role or process: immune, antigen presentation, & tissue remodelling; lineage: hematopoietic, myeloid." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "histiocyte" @@ -1845,7 +1854,7 @@ "val" : "A lymphocyte of B lineage that is capable of B cell mediated immunity.", "xrefs" : [ "GOC:add", "GOC:tfm", "GO_REF:0000031", "ISBN:0781735149" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "B lymphocyte" @@ -1877,6 +1886,7 @@ "lbl" : "eukaryotic cell", "type" : "CLASS", "meta" : { + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "MESH:D005057" } ] @@ -1979,7 +1989,7 @@ "val" : "A cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation. These cells are lineage negative (CD3-negative, CD19-negative, CD34-negative, and CD56-negative).", "xrefs" : [ "GOC:add", "ISBN:0781735149" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "interdigitating cell" @@ -2052,7 +2062,7 @@ "xrefs" : [ "MESH:D009474", "http://en.wikipedia.org/wiki/Neuron" ] }, "comments" : [ "These cells are also reportedly CD4-negative and CD200-positive. They are also capable of producing CD40L and IFN-gamma." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "nerve cell" @@ -2088,7 +2098,7 @@ "xrefs" : [ "GOC:add", "ISBN:0683073696", "ISBN:0781735149" ] }, "comments" : [ "Editors note: consider adding taxon constraint to vertebrata (PMID:18025161)" ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { "val" : "BTO:0000775" }, { @@ -2114,7 +2124,7 @@ "val" : "An immature, nucleated erythrocyte occupying the stage of erythropoeisis that follows formation of erythroid progenitor cells. This cell is CD71-positive, has both a nucleus and a nucleolus, and lacks hematopoeitic lineage markers.", "xrefs" : [ "ISBN:0721601464", "PMID:1638021" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "rubriblast", @@ -2238,7 +2248,7 @@ "xrefs" : [ "GOC:dsd", "GOC:tfm", "ISBN:0721601464" ] }, "comments" : [ "Lineage negative is described here as CD2-negative, CD3-negative, CD4-negative, CD5-negative, CD8a-negative, CD14-negative, CD19-negative, CD20-negative, CD56-negative, Ly6g-negative, and Ter119-negative." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "CFU-Meg", @@ -2298,7 +2308,7 @@ "xrefs" : [ "ISBN:0721601464", "MESH:D008533", "PMID:31043076", "http://en.wikipedia.org/wiki/Megakaryocyte" ] }, "comments" : [ "Megakaryocytes are reportedly CD181-positive and CD182-positive." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "megacaryocyte" @@ -2331,7 +2341,7 @@ "xrefs" : [ "GOC:amm", "GOC:dsd", "GOC:tfm", "GO_REF:0000031", "ISBN:0721601464", "MESH:D055014", "PMCID:PMC2213186", "PMCID:PMC548021", "PMID:16551251", "PMID:16647566", "http://en.wikipedia.org/wiki/CFU-GM", "http://www.copewithcytokines.de" ] }, "comments" : [ "Originally described in the dendritic cell ontology (DC_CL:0000042)(PMID:19243617). GMPs are reportedly CD16-positive, CD32-positive, CD34-positive, CD38-positive, CD45RA-positive, CD110-negative, CD117-positive, CD123-positive, and SCA1-negative." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "CFU-C , Colony forming unit in culture", @@ -2375,7 +2385,7 @@ "val" : "An immature erythrocyte that changes the protein composition of its plasma membrane by exosome formation and extrusion. The types of protein removed differ between species though removal of the transferrin receptor is apparent in mammals and birds.", "xrefs" : [ "GOC:add", "GOC:tfm", "PMID:15946868", "PMID:2037622" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "BTO:0001173" }, { @@ -2394,7 +2404,7 @@ "xrefs" : [ "GOC:tfm", "ISBN:0721601464" ] }, "comments" : [ "Morphology: Mononuclear cell, diameter 14-18 _M, fine azurophilic granules; markers: CD11b (shared with many other myeloid cells); location: Adult: bone marrow; Fetal: Liver, Yolk Sac; role or process: hematopoiesis, monocyte development; lineage: hematopoietic, myeloid." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { "val" : "BTO:0004657" }, { @@ -2433,7 +2443,7 @@ "xrefs" : [ "GO_REF:0000031", "MESH:D009000" ] }, "comments" : [ "Morphology: Mononuclear cell, diameter, 14 to 20 _M, N/C ratio 2:1-1:1. Nucleus may appear in variety of shapes: round, kidney, lobulated, or convoluted. Fine azurophilic granules present; markers: CD11b (shared with other myeloid cells), human: CD14, mouse: F4/80-mid,GR1-low; location: Blood, but can be recruited into tissues; role or process: immune & tissue remodelling; lineage: hematopoietic, myeloid." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { "val" : "BTO:0000876" }, { @@ -2494,7 +2504,8 @@ "definition" : { "val" : "A non-terminally differentiated cell that is capable of developing into a muscle cell.", "xrefs" : [ "GOC:add" ] - } + }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000723", @@ -2520,7 +2531,7 @@ "val" : "An achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue.", "xrefs" : [ "GOC:add", "GOC:tfm", "ISBN:978-0-323-05290-0" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "leucocyte" @@ -2568,6 +2579,7 @@ "val" : "A cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage.", "xrefs" : [ "GOC:add" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "BTO:0001441" }, { @@ -2586,7 +2598,7 @@ "xrefs" : [ "GOC:add", "GOC:tfm" ] }, "comments" : [ "Note that in FMA erythropoietic cells are types of nucleated erythrocytes and thus don't include erythrocytes." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "erythropoietic cell" @@ -2612,7 +2624,7 @@ "val" : "A nucleated precursor of an erythrocyte that lacks hematopoietic lineage markers.", "xrefs" : [ "GOC:add", "ISBN:0721601464", "PMID:18174176" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "normoblast" @@ -2635,7 +2647,8 @@ "definition" : { "val" : "A cell of the monocyte, granulocyte, or mast cell lineage.", "xrefs" : [ "GOC:add" ] - } + }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000767", @@ -2647,7 +2660,7 @@ "xrefs" : [ "GOC:add", "GOC:amm", "GOC:dsd", "GOC:tfm", "ISBN:0721601464", "MESH:D001491", "PMCID:PMC2626675", "PMID:11927641", "PMID:19741522", "PMID:21236338", "PMID:9933081" ] }, "comments" : [ "Matures in the bone marrow and account for <1% of leukocytes in the peripheral blood, spleen, and bone marrow. Basophils are described as being CD11a-positive, CD11b-positive, CD13-positive, CD15-positive, CD18-positive, CD21-positive, CD25-positive, CD29-positive, CD35-positive, CD40-positive, CD40L-positive, CD44-positive, CD45R-negative, CD46-positive, CD49a-positive, CD49b-positive, CD49d-positive, CD55-positive, CD59-positive, CD62L-positive, CD63-positive, CD69-positive, CD90-negative, CD116-positive, CD117-negative, CD124-positive, CD125-positive, CD131-positive, CD161-positive, CD184-positive, CD191-positive, CD192-positive, CD197-positive, CD200R3-positive, CD218-positive, CD282-positive, CD284-positive, CD289-positive, CD290-positive, CD294-positive, natural killer cell receptor 2B4-positive, smad1-positive, CD3-negative, CD4-negative, CD7-negative, CD8-negative, CD14-negative, CD15-negative, CD16-negative, CD19-negative, CD20-negative, CD34-negative, CD36-negative, CD45R-negative, CD56-negative, CD57-negative, CD235a-negative, and GR1-negative. Transcription factors- GATA1-positive, PU.1-positive." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "polymorphonuclear leucocyte" @@ -2683,7 +2696,7 @@ "xrefs" : [ "GOC:add", "GOC:amm", "GOC:dsd", "GOC:tfm", "ISBN:0721601464", "PMCID:PMC2626675", "PMID:10914487", "PMID:1662676" ] }, "comments" : [ "Eosinophils are also CD14-negative, CD32-positive, CD44-positive, CD48-positive, CD69-positive, CD192-negative, MBP1-positive, MBP2-positive, TLR2-negative, TLR4-negative, and lineage-negative (B220, CD2, CD14, CD19, CD56, CD71, CD117, CD123, CD235a (glycophorin A), and TER119). The cytokines IL-3, IL-5, and GM-CSF are involved in their development and differentiation. Usually considered CD16-negative, CD16 is observed on eosinophilic metamyelocyte." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "polymorphonuclear leucocyte" @@ -2726,7 +2739,7 @@ "val" : "Any of the immature or mature forms of a granular leukocyte that in its mature form has a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes.", "xrefs" : [ "GOC:add", "GOC:amm", "GOC:tfm", "ISBN:0721601464" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "PMN" @@ -2788,6 +2801,7 @@ "xrefs" : [ "GOC:add", "PMID:10449155", "PMID:17332250", "PMID:9521319" ] }, "comments" : [ "These cells are CD1a-negative, CD1b-positive, CD11a-positive, CD11c-positive, CD13-positive, CD14-negative, CD20-negative, CD21-negative, CD33-positive, CD40-negative, CD50-positive, CD54-positive, CD58-positive, CD68-negative, CD80-negative, CD83-negative, CD85j-positive, CD86-positive, CD89-negative, CD95-positive, CD120a-negative, CD120b-positive, CD123-negative, CD178-negative, CD206-negative, CD207-negative, CD209-negative, and TNF-alpha-negative. Upon TLR stimulation, they are capable of producing high levels of TNF-alpha, IL-6, CXCL8 (IL-8)." ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "interdigitating cell" @@ -2814,7 +2828,7 @@ "val" : "A dendritic cell type of distinct morphology, localization, and surface marker expression (CD123-positive) from other dendritic cell types and associated with early stage immune responses, particularly the release of physiologically abundant amounts of type I interferons in response to infection.", "xrefs" : [ "GOC:add", "GOC:dsd", "PMCID:PMC2118448", "PMCID:PMC538703", "PMID:15549123", "PMID:17332250", "PMID:17850486", "PMID:20304825" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "DC2" @@ -2861,6 +2875,7 @@ "xrefs" : [ "GOC:add", "GOC:dsd", "ISBN:0781735149" ] }, "comments" : [ "Mature B cells are also reportedly CD10-negative, CD19-positive, CD22-positive, CD34-negative, CD48-positive, CD79a-positive, CD84-positive, CD127-negative, CD352-positive, RAG-negative, TdT-negative, Vpre-B-negative, and pre-BCR-negative. Transcription factors expressed: Pax5-positive." ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "mature B lymphocyte" @@ -2882,7 +2897,7 @@ "xrefs" : [ "GOC:add", "GOC:dsd", "GO_REF:0000031", "ISBN:0721601464", "ISBN:0781735149", "PMID:19447676", "PMID:20081059", "PMID:20839338", "PMID:20951740", "http://en.wikipedia.org/wiki/Plasma_cell" ] }, "comments" : [ "Plasma cells develop in the spleen and migrate to the bone marrow. Plasma cells are also reportedly CD5-negative, CD10-negative, CD19-positive, CD20-negative, CD21-negative, CD22-negative, CD23-negative, CD24-negative, CD25-negative, CD27-positive, CD34-negative, CD38-positive, CD40-positive, CD43-positive, CD45-positive, CD48-positive, CD53-low, CD80-negative, CD81-positive, CD86-positive, CD95-positive, CD196-negative, CD229-positive, CD270-positive, CD352-positive, CD361-positive, and IgD-negative. Transcription factors: BLIMP1-positive, IRF4-positive, PAX5-negative, SpiB-negative, Ets1-negative, and XBP1-positive." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "plasma B cell" @@ -2923,7 +2938,7 @@ "val" : "A T cell that expresses an alpha-beta T cell receptor complex.", "xrefs" : [ "GOC:add", "GOC:tfm", "ISBN:0781735149" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "alpha-beta T lymphocyte" @@ -2945,7 +2960,7 @@ "xrefs" : [ "GOC:add", "GOC:tfm", "ISBN:0781735149" ] }, "comments" : [ "Note that gamma-delta T cells have both thymic and extrathymic differentiation pathways." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "gamma-delta T lymphocyte" @@ -2978,7 +2993,7 @@ "xrefs" : [ "GOC:add", "GOC:dsd", "GOC:rhs", "GOC:tfm", "GO_REF:0000031", "ISBN:0781735149", "PMID:20081059", "PMID:20839338" ] }, "comments" : [ "Immature B cells are also reportedly CD5-positive, CD10-positive, CD19-positive, CD20-positive, CD21-positive, CD22-positive, CD24-positive, CD25-negative, CD27-negative, CD34-negative, CD38-positive, CD40-positive, CD43-negative, CD45-positive, CD48-positive, CD53-positive, CD79a-positive, CD80-negative, CD81-positive, CD86-negative, CD95-negative, CD127-negative, CD138-negative, CD185-positive, CD196-positive, MHCII/HLA-DR-positive, RAG-positive, TdT-negative, Vpre-B-negative, and preBCR-negative. Transcription factors expressed: Pax5-positive." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "immature B lymphocyte" @@ -3007,7 +3022,7 @@ "val" : "A precursor B cell is a B cell with the phenotype CD10-positive.", "xrefs" : [ "GOC:rhs", "GOC:tfm", "GO_REF:0000031" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "pre-B cell" @@ -3032,7 +3047,7 @@ "xrefs" : [ "GOC:add", "GO_REF:0000031", "ISBN:0781735149", "PMID:12810111", "PMID:22343568" ] }, "comments" : [ "This cell type is compatible with the HIPC Lyoplate markers for 'transitional B cell'." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "transitional B cell", @@ -3071,7 +3086,7 @@ "xrefs" : [ "GOC:add", "GOC:dsd", "ISBN:0781735149", "PMID:12633665", "PMID:16551251", "PMID:18432934" ] }, "comments" : [ "Human pro-B cells are reportedly CD10-positive, CD22-positive, CD34-positive, CD38-positive, CD45-low, CD48-positive, CD79a-positive, CD127-positive, CD184-positive, RAG-positive, TdT-positive, Vpre-B-positive, pre-BCR-negative, IgD-negative, and IgM-negative. Transcription factors expressed: Pax5-positive, EBF-positive, E2A-negative, Ikaros-negative, and PU.1-negative." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "pre-pro B cell", @@ -3119,6 +3134,7 @@ "val" : "A lymphoid progenitor cell of the T cell lineage, with some lineage specific marker expression, but not yet fully committed to the T cell lineage.", "xrefs" : [ "GOC:add", "ISBN:0781735149" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "pro-T lymphocyte" @@ -3181,7 +3197,7 @@ "xrefs" : [ "GOC:add", "GOC:tfm", "PMID:19022770" ] }, "comments" : [ "Markers differ between mouse and human." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "MPP" @@ -3209,6 +3225,7 @@ "xrefs" : [ "GOC:add", "GOC:tfm" ] }, "comments" : [ "Note that this is a class of cell types, not an identified single cell type." ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "lymphoid progenitor cell" @@ -3231,7 +3248,7 @@ "xrefs" : [ "GOC:add", "GOC:tfm", "PMID:19022770" ] }, "comments" : [ "Note that this is a class of cell types, not an identified single cell type." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "myeloid progenitor cell" @@ -3257,7 +3274,7 @@ "val" : "A leukocyte with a single non-segmented nucleus in the mature form.", "xrefs" : [ "GOC:add" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "mononuclear leukocyte" @@ -3321,6 +3338,7 @@ "xrefs" : [ "GOC:dsd", "GOC:rhs", "GOC:tfm", "GO_REF:0000031", "PMID:16551251", "PMID:18432934", "PMID:9785673" ] }, "comments" : [ "Small pre-B-II cells are also reportedly CD10-positive, CD19-positive, CD34-negative, CD79a-positive, CD127-negative, TdT-negative, Vpre-B-negative, sIgM-negative, and sIgD-negative. Transcription factors: PU.1-positive, Ikaros-positive, E2A-positive, and PAX5-positive." ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "small pre-BII cell" @@ -3359,7 +3377,7 @@ "xrefs" : [ "GOC:dsd", "GOC:msz", "GOC:tfm", "GO_REF:0000031", "PMCID:PMC2673126" ] }, "comments" : [ "This cell type is compatible with the HIPC Lyoplate markers for 'plasmablast'. Plasmablasts are also reportedly CD48-positive, CD63-positive, CD229-positive, CD270-positive, CD319-positive, CD352-positive, CD361-positive, and IgD-negative." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "CD20-negative B cell" @@ -3384,6 +3402,7 @@ "val" : "A cell of a hematopoietic lineage.", "xrefs" : [ "GOC:add", "GO_REF:0000031" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "haematopoietic cell" @@ -3414,7 +3433,7 @@ "xrefs" : [ "GOC:amm", "GO_REF:0000031", "PMID:17850486" ] }, "comments" : [ "Originally described in the dendritic cell ontology (DC_CL:0000003)(PMID:19243617) These cells are also CD20-negative, MHCII-positive." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "interdigitating cell" @@ -3496,7 +3515,7 @@ "val" : "A lymphocyte that lacks characteristic T cell, B cell, myeloid cell, and dendritic cell markers, that functions as part of the innate immune response to produce cytokines and other effector responses.", "xrefs" : [ "GOC:add", "GOC:dsd", "PMID:23292121", "PMID:23348417" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" @@ -3562,6 +3581,7 @@ "val" : "A progenitor cell that can give rise to plasmacytoid and myeloid dendritic cells, and to monocytes and macrophages.", "xrefs" : [ "GOC:tfm", "PMID:19273628" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "MDP" @@ -3584,6 +3604,7 @@ "xrefs" : [ "GOC:ak", "GOC:dsd", "GOC:tfm", "PMCID:PMC1312421" ] }, "comments" : [ "There may be an intermediate cell type. These cells also CD13-positive, CD16-positive, CD32-positive, and integrin beta 7-positive. Transcription factors: GATA1-positive, MCP-1-positive, mitf-positive, PU.1-positive, and CEBP/a-low." ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "BMCP" @@ -3712,6 +3733,7 @@ "xrefs" : [ "GOC:tfm", "ISBN:0618947256" ] }, "comments" : [ "MH consider whether bone marrow cells are bone cells in the structural sense vs. being part of bone organ sense." ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "BTO:0004850" }, { @@ -3737,6 +3759,7 @@ "xrefs" : [ "GOC:dsd", "GOC:tfm", "PMID:12768659" ] }, "comments" : [ "These cells are reportedly CD31-positive, CD34-positive, CD144-positive, TAL1-positive." ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "vascular endothelial cell" @@ -3768,6 +3791,7 @@ "val" : "A cell involved in the formation of a granulocyte.", "xrefs" : [ "GOC:tfm" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "FMA:83519" } ], @@ -3845,6 +3869,7 @@ "val" : "A cell that is part of the nervous system.", "xrefs" : [ "GOC:tfm", "ISBN:0618947256" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "CALOHA:TS-2040" }, { @@ -3867,6 +3892,7 @@ "val" : "A cell of the supporting or framework tissue of the body, arising chiefly from the embryonic mesoderm and including adipose tissue, cartilage, and bone.", "xrefs" : [ "GOC:tfm", "ISBN:0618947256" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "CALOHA:TS-2096" }, { @@ -3915,7 +3941,7 @@ "val" : "A T cell that has not completed T cell selection.", "xrefs" : [ "GOC:tfm" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "immature T-cell" @@ -4048,7 +4074,8 @@ "definition" : { "val" : "Any hematopoietic cell that is a precursor of some other hematopoietic cell type.", "xrefs" : [ "GOC:dos" ] - } + }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0008019", @@ -4058,7 +4085,7 @@ "definition" : { "val" : "A non-polarised cell precursor cell that is part of some mesenchyme, is associated with the cell matrix but is not connected to other cells and is capable of migration." }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "mesenchyme cell" @@ -4092,7 +4119,8 @@ "definition" : { "val" : "A cell of the neural crest. Neural crest cells are multipotent. Premigratory neural crest cells are found at the neural plate boarder, some of which will undergo ectomesynchymal transition and delamination to form migratory neural crest cells.", "xrefs" : [ "https://orcid.org/0000-0001-5208-3432", "https://orcid.org/0000-0002-9900-7880" ] - } + }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0011026", @@ -4103,6 +4131,7 @@ "val" : "A precursor cell that has a tendency to differentiate into a specific type of cell. They are descendants of stem cells, only they are more constrained in their differentiation potential or capacity for self-renewal, and are often more limited in both senses.", "xrefs" : [ "ISBN:978-1-62808-994-3", "https://doi.org/10.1016/B978-0-12-409503-8.00002-0" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0001-5208-3432" @@ -4117,7 +4146,8 @@ "val" : "A cell that, by division or terminal differentiation, can give rise to other cell types.", "xrefs" : [ "GOC:dos" ] }, - "comments" : [ "Work is needed on GO 'cell differentiation' before it is clear whether the equivalent class definition 'native cell' that capable_of some 'cell differentiation' works. Also, may want to consider merging this with non-terminally differentiated cell." ] + "comments" : [ "Work is needed on GO 'cell differentiation' before it is clear whether the equivalent class definition 'native cell' that capable_of some 'cell differentiation' works. Also, may want to consider merging this with non-terminally differentiated cell." ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0017005", @@ -4239,23 +4269,6 @@ "val" : "2009-12-28T04:25:23Z" } ] } - }, { - "id" : "http://purl.obolibrary.org/obo/CL_0017505", - "lbl" : "increased nucleus size", - "type" : "CLASS", - "meta" : { - "definition" : { - "val" : "A nucleus size quality which is relatively high compared to the amount of cytoplasm present in the same cell.", - "xrefs" : [ "GOC:tfm" ] - }, - "basicPropertyValues" : [ { - "pred" : "http://purl.org/dc/terms/contributor", - "val" : "https://orcid.org/0000-0003-1980-3228" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", - "val" : "2009-12-23T10:53:24Z" - } ] - } }, { "id" : "http://purl.obolibrary.org/obo/CL_0017508", "lbl" : "cartwheel heterochromatin", @@ -4304,6 +4317,7 @@ "val" : "A leukocyte with a single non-segmented nucleus in the mature form found in the circulatory pool of blood.", "xrefs" : [ "GOC:TermGenie" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://www.wikidata.org/entity/Q35563349" @@ -6349,7 +6363,7 @@ "type" : "CLASS", "meta" : { "definition" : { - "val" : "A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex).", + "val" : "A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex).", "xrefs" : [ "GOC:pdt" ] }, "comments" : [ "Note that, in addition to forming the root of the cellular component ontology, this term is recommended for the annotation of gene products whose cellular component is unknown. When this term is used for annotation, it indicates that no information was available about the cellular component of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this." ], @@ -6389,7 +6403,7 @@ "xrefs" : [ "GOC:go_curators" ] }, "comments" : [ "Note that this term is intended to annotate gene products that are not attached to the cell surface. For gene products from multicellular organisms which are secreted from a cell but retained within the organism (i.e. released into the interstitial fluid or blood), consider the cellular component term 'extracellular space ; GO:0005615'." ], - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_yeast", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "extracellular" @@ -6507,7 +6521,7 @@ "xrefs" : [ "ISBN:0198547684" ] }, "comments" : [ "Note that for multicellular organisms, the extracellular space refers to everything outside a cell, but still within the organism (excluding the extracellular matrix). Gene products from a multi-cellular organism that are secreted from a cell into the interstitial fluid or blood can therefore be annotated to this term." ], - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "intercellular space" @@ -6597,7 +6611,7 @@ "xrefs" : [ "ISBN:0198547684" ] }, "comments" : [ "Chromosomes include parts that are not part of the chromatin. Examples include the kinetochore." ], - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_yeast", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "interphase chromosome" @@ -6645,7 +6659,7 @@ "val" : "The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.", "xrefs" : [ "ISBN:0198547684" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_yeast", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "xrefs" : [ { "val" : "Wikipedia:Cytoplasm" } ], @@ -6759,7 +6773,7 @@ "val" : "An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins.", "xrefs" : [ "ISBN:0198506732" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_yeast", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "free ribosome", @@ -6794,7 +6808,7 @@ "val" : "The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.", "xrefs" : [ "ISBN:0716731363" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_yeast", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "juxtamembrane" @@ -6909,7 +6923,7 @@ "val" : "Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction.", "xrefs" : [ "ISBN:0198506732" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_pombe", "http://purl.obolibrary.org/obo/go#goslim_yeast", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_pombe", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" @@ -6924,7 +6938,7 @@ "val" : "The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.", "xrefs" : [ "GOC:go_curators" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "protein anabolism" @@ -7063,7 +7077,7 @@ "xrefs" : [ "GOC:dos", "GOC:dph", "GOC:jl", "GOC:mah" ] }, "comments" : [ "Note that this term should not be used for direct annotation. It should be possible to make a more specific annotation to one of the children of this term, for e.g. to transmembrane transport, to microtubule-based transport or to vesicle-mediated transport." ], - "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "single-organism transport" @@ -8070,7 +8084,7 @@ "val" : "Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538).", "xrefs" : [ "GOC:mah", "GOC:mtg_apoptosis", "PMID:25236395" ] }, - "comments" : [ "This term should not be used for direct annotation, it is currently kept in GO as a placeholder for describing cell death phenotypes in uPHENO. When information is provided on a programmed cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'). Unintentional cell death, i.e. cell death caused by injury, ageing, or cell phenotypes observed as a result of a pathological mutation in an essential gene should NOT be annotated using GO terms." ], + "comments" : [ "This term should not be used for direct annotation, it is currently kept in GO as a placeholder for describing cell death phenotypes in uPHENO. When information is provided on a programmed cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'). Unintentional cell death, i.e. cell death caused by injury, ageing, or cell phenotypes observed as a result of a pathological mutation in an essential gene should NOT be annotated using GO terms." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", @@ -8474,7 +8488,7 @@ "xrefs" : [ "GOC:lr", "GOC:mtg_apoptosis" ] }, "comments" : [ "Note that this term should be used to annotate gene products in the organism undergoing the programmed cell death. To annotate genes in another organism whose products modulate programmed cell death in a host organism, consider the term 'modulation by symbiont of host programmed cell death ; GO:0052040'. Also, note that 'programmed cell death ; GO:0012501' should be used to refer to instances of caspase-independent cell death mechanisms, in the absence of further indications on the process taking place. At present, caspase-independent cell death is not yet represented in GO due to the lack of consensus and in-depth research on the topic. 'programmed cell death ; GO:0012501' may also be used to annotate gene products in taxa where apoptosis as defined in GO:0006915 does not occur, such as plants. You may also consider these specific children: GO:0097468 'programmed cell death in response to reactive oxygen species' (with descendants GO:0010421 'hydrogen peroxide-mediated programmed cell death' and GO:0010343 'singlet oxygen-mediated programmed cell death'), and GO:0009626 'plant-type hypersensitive response' and its children." ], - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "regulated cell death" @@ -9198,7 +9212,7 @@ "xrefs" : [ "GOC:mtg_signal", "GOC:mtg_signaling_feb11", "GOC:signaling" ] }, "comments" : [ "Note that a signal is any variable property or parameter that serves to convey information, and may be a physical entity such as a gene product or small molecule, a photon, or a change in state such as movement or voltage change." ], - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pombe", "http://purl.obolibrary.org/obo/go#goslim_yeast", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pombe", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "biological signaling" @@ -9264,7 +9278,7 @@ "val" : "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon.", "xrefs" : [ "GOC:jl", "GOC:mah", "http://www.cogsci.princeton.edu/~wn/" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cell projection organisation" @@ -9899,7 +9913,7 @@ "val" : "A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues.", "xrefs" : [ "GOC:BHF", "GOC:mah", "GOC:rph", "NIF_Subcellular:nlx_subcell_20090513", "PMID:21123617", "PMID:28089324" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "proteinaceous extracellular matrix" @@ -11159,7 +11173,7 @@ "val" : "A prolongation or process extending from a cell, e.g. a flagellum or axon.", "xrefs" : [ "GOC:jl", "http://www.cogsci.princeton.edu/~wn/" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "cell process" @@ -11215,7 +11229,7 @@ "val" : "The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.", "xrefs" : [ "GOC:mah" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_pir" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_pir" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "biopolymer metabolic process", @@ -11231,6 +11245,9 @@ "val" : "multicellular organismal macromolecule metabolic process" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/26424" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0034960" }, { @@ -11267,7 +11284,7 @@ "val" : "Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane.", "xrefs" : [ "GOC:go_curators" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "xrefs" : [ { "val" : "NIF_Subcellular:sao1539965131" }, { @@ -11568,12 +11585,15 @@ "val" : "The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.", "xrefs" : [ "GOC:go_curators", "http://www.metacyc.org" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_pir" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_pir" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "primary metabolism" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/26424" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] @@ -12338,12 +12358,15 @@ "val" : "The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.", "xrefs" : [ "GO_REF:0000021" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_plant" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_plant" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "development of an anatomical structure" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/26424" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] @@ -12371,7 +12394,7 @@ "val" : "Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another.", "xrefs" : [ "GOC:dgh", "GOC:dph", "GOC:isa_complete", "GOC:mlg" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cell locomotion" @@ -12665,7 +12688,7 @@ "xrefs" : [ "GOC:ai", "GOC:bf" ] }, "comments" : [ "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ], - "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_manually_annotate", "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_manually_annotate", "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "physiological response to stimulus" @@ -13044,7 +13067,7 @@ "val" : "A compound molecular function in which an effector function is controlled by one or more regulatory components.", "xrefs" : [ "GOC:dos", "GOC:pdt" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_manually_annotate", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_manually_annotate", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "molecular_function" @@ -13155,7 +13178,7 @@ "val" : "A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.", "xrefs" : [ "GOC:dph", "GOC:tb" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_pombe", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_pombe", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cellular membrane organisation" @@ -13277,7 +13300,7 @@ "val" : "The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex.", "xrefs" : [ "GOC:jl" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_pombe", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_pombe", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cellular protein complex assembly" @@ -13487,6 +13510,7 @@ "val" : "The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon.", "xrefs" : [ "GOC:mah" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "organic molecular entity metabolic process" @@ -13498,6 +13522,9 @@ "val" : "organic substance metabolism" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/26424" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "mah" }, { @@ -13697,7 +13724,7 @@ "type" : "CLASS", "meta" : { "definition" : { - "val" : "The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures.", + "val" : "The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures.", "xrefs" : [ "GOC:pdt" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon" ], @@ -13925,7 +13952,7 @@ "val" : "Reactions triggered in response to the presence of another organism that act to protect the cell or organism from damage caused by that organism.", "xrefs" : [ "GOC:dos" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "defence response incompatible interaction" @@ -14258,6 +14285,9 @@ "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/24200" + }, { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/26424" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "kmv" @@ -14443,6 +14473,29 @@ "val" : "biological_process" } ] } + }, { + "id" : "http://purl.obolibrary.org/obo/GO_0140546", + "lbl" : "defense response to symbiont", + "type" : "CLASS", + "meta" : { + "definition" : { + "val" : "Reactions triggered in response to the presence of a symbiont that act to protect or prevent damage to the host.", + "xrefs" : [ "GOC:pg" ] + }, + "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/20261" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", + "val" : "pg" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", + "val" : "2020-11-11T17:19:06Z" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "biological_process" + } ] + } }, { "id" : "http://purl.obolibrary.org/obo/GO_1901576", "lbl" : "organic substance biosynthetic process", @@ -16111,47 +16164,6 @@ "val" : "quality" } ] } - }, { - "id" : "http://purl.obolibrary.org/obo/PATO_0000068", - "lbl" : "qualitative", - "type" : "CLASS", - "meta" : { - "comments" : [ "TODO: define this or obsolete it and move children somewhere else." ], - "basicPropertyValues" : [ { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", - "val" : "quality" - } ] - } - }, { - "id" : "http://purl.obolibrary.org/obo/PATO_0000069", - "lbl" : "deviation (from_normal)", - "type" : "CLASS", - "meta" : { - "definition" : { - "val" : "A quality inhering in a bearer by virtue of the whether the bearer differs from normal or average.", - "xrefs" : [ "PATOC:GVG" ] - }, - "subsets" : [ "http://purl.obolibrary.org/obo/pato#attribute_slim" ], - "basicPropertyValues" : [ { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", - "val" : "quality" - } ] - } - }, { - "id" : "http://purl.obolibrary.org/obo/PATO_0000117", - "lbl" : "size", - "type" : "CLASS", - "meta" : { - "definition" : { - "val" : "A morphology quality inhering in a bearer by virtue of the bearer's physical magnitude.", - "xrefs" : [ "WordNet:WordNet" ] - }, - "subsets" : [ "http://purl.obolibrary.org/obo/pato#attribute_slim", "http://purl.obolibrary.org/obo/pato#scalar_slim" ], - "basicPropertyValues" : [ { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", - "val" : "quality" - } ] - } }, { "id" : "http://purl.obolibrary.org/obo/PATO_0000141", "lbl" : "structure", @@ -16240,65 +16252,6 @@ "val" : "quality" } ] } - }, { - "id" : "http://purl.obolibrary.org/obo/PATO_0000461", - "lbl" : "normal", - "type" : "CLASS", - "meta" : { - "definition" : { - "val" : "A quality inhering in a bearer by virtue of the bearer's exhibiting no deviation from normal or average.", - "xrefs" : [ "PATOC:GVG" ] - }, - "subsets" : [ "http://purl.obolibrary.org/obo/pato#abnormal_slim", "http://purl.obolibrary.org/obo/pato#mpath_slim", "http://purl.obolibrary.org/obo/pato#value_slim" ], - "synonyms" : [ { - "pred" : "hasRelatedSynonym", - "val" : "average" - } ], - "basicPropertyValues" : [ { - "pred" : "http://purl.obolibrary.org/obo/RO_0002604", - "val" : "http://purl.obolibrary.org/obo/PATO_0000460" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", - "val" : "quality" - } ] - } - }, { - "id" : "http://purl.obolibrary.org/obo/PATO_0000586", - "lbl" : "increased size", - "type" : "CLASS", - "meta" : { - "definition" : { - "val" : "A size quality which is relatively high.", - "xrefs" : [ "PATOC:GVG" ] - }, - "subsets" : [ "http://purl.obolibrary.org/obo/pato#value_slim" ], - "synonyms" : [ { - "pred" : "hasRelatedSynonym", - "val" : "big" - }, { - "pred" : "hasRelatedSynonym", - "val" : "enlarged" - }, { - "pred" : "hasRelatedSynonym", - "val" : "expanded" - }, { - "pred" : "hasRelatedSynonym", - "val" : "great" - }, { - "pred" : "hasRelatedSynonym", - "val" : "large" - } ], - "basicPropertyValues" : [ { - "pred" : "http://purl.obolibrary.org/obo/RO_0002604", - "val" : "http://purl.obolibrary.org/obo/PATO_0000587" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", - "val" : "PATO:0001202" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", - "val" : "quality" - } ] - } }, { "id" : "http://purl.obolibrary.org/obo/PATO_0000947", "lbl" : "elliptic", @@ -17008,52 +16961,6 @@ "val" : "quality" } ] } - }, { - "id" : "http://purl.obolibrary.org/obo/PATO_0002300", - "lbl" : "increased quality", - "type" : "CLASS", - "meta" : { - "definition" : { - "val" : "A quality that has a value that is increased compared to normal or average.", - "xrefs" : [ "PATOC:GVG" ] - }, - "basicPropertyValues" : [ { - "pred" : "http://purl.obolibrary.org/obo/RO_0002604", - "val" : "http://purl.obolibrary.org/obo/PATO_0002301" - }, { - "pred" : "http://purl.org/dc/terms/contributor", - "val" : "https://orcid.org/0000-0002-2061-091X" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", - "val" : "2011-06-16T06:39:43Z" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", - "val" : "quality" - } ] - } - }, { - "id" : "http://purl.obolibrary.org/obo/PATO_0002305", - "lbl" : "increased object quality", - "type" : "CLASS", - "meta" : { - "definition" : { - "val" : "A quality of an object that has a value that is increased compared to normal or average.", - "xrefs" : [ "PATOC:GVG" ] - }, - "basicPropertyValues" : [ { - "pred" : "http://purl.obolibrary.org/obo/RO_0002604", - "val" : "http://purl.obolibrary.org/obo/PATO_0002303" - }, { - "pred" : "http://purl.org/dc/terms/contributor", - "val" : "https://orcid.org/0000-0002-2061-091X" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", - "val" : "2011-06-16T06:54:01Z" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", - "val" : "quality" - } ] - } }, { "id" : "http://purl.obolibrary.org/obo/PATO_0002318", "lbl" : "superelliptic", @@ -17161,6 +17068,28 @@ "val" : "quality" } ] } + }, { + "id" : "http://purl.obolibrary.org/obo/PATO_0040072", + "lbl" : "high nuclear/cytoplasmic ratio", + "type" : "CLASS", + "meta" : { + "definition" : { + "val" : "A quality inhering in a cell by virtue of the cell having a high nuclear/cytoplasmic ratio.", + "xrefs" : [ "Wikipedia:NC_ratio&oldid=931936284", "http://lymerick.net/blood-cells.pdf" ] + }, + "comments" : [ "A high nuclear/cytolasmic ratio is 70% or higher." ], + "synonyms" : [ { + "pred" : "hasExactSynonym", + "val" : "high N:C ratio" + } ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", + "val" : "http://orcid.org/0000-0001-5208-3432" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "quality" + } ] + } }, { "id" : "http://purl.obolibrary.org/obo/PATO_0070044", "lbl" : "anatomical structure quality", @@ -22110,6 +22039,9 @@ "val" : "inverse of develops from" }, "subsets" : [ "http://purl.obolibrary.org/obo/RO_0002259" ], + "xrefs" : [ { + "val" : "RO:0002203" + } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000114", "val" : "http://purl.obolibrary.org/obo/IAO_0000125" @@ -22122,6 +22054,12 @@ }, { "pred" : "http://purl.obolibrary.org/obo/IAO_0000117", "val" : "https://orcid.org/0000-0003-1980-3228" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "uberon" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#shorthand", + "val" : "develops_into" } ] } }, { @@ -27087,7 +27025,7 @@ "val" : "zygote", "xrefs" : [ "VHOG:0000745" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "zygotum", "xrefs" : [ "Wikipedia:Zygote" ] @@ -27364,7 +27302,7 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#efo_slim", "http://purl.obolibrary.org/obo/uberon/core#major_organ", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "regio oralis", "xrefs" : [ "BTO:0004698", "FMA:49184", "FMA:TA" ] @@ -27372,7 +27310,7 @@ "pred" : "hasNarrowSynonym", "val" : "adult mouth" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "cavital oralis", "xrefs" : [ "Wikipedia:Mouth" ] @@ -28390,8 +28328,6 @@ "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#common_anatomy", "http://purl.obolibrary.org/obo/uberon/core#upper_level" ], "xrefs" : [ { "val" : "FBbt:00007277" - }, { - "val" : "IDOMAL:0002461" }, { "val" : "VHOG:0001737" } ], @@ -29609,7 +29545,7 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "systema cardiovasculare", "xrefs" : [ "Wikipedia:Circulatory_system" ] @@ -29618,6 +29554,8 @@ "val" : "AAO:0000959" }, { "val" : "CALOHA:TS-2103" + }, { + "val" : "MESH:D002319" }, { "val" : "VHOG:0001248" }, { @@ -29675,7 +29613,7 @@ "pred" : "hasExactSynonym", "val" : "musculature" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "musculi", "xrefs" : [ "FMA:32558", "FMA:TA" ] @@ -29749,7 +29687,7 @@ "val" : "The nervous system is an organ system containing predominantly neuron and glial cells. In bilaterally symmetrical organism, it is arranged in a network of tree-like structures connected to a central body. The main functions of the nervous system are to regulate and control body functions, and to receive sensory input, process this information, and generate behavior [CUMBO].", "xrefs" : [ "BIRNLEX:844", "ISBN:0-14-051288-8", "ISBN:3110148986", "NLM:nervous+system", "WB:rynl", "Wikipedia:Nervous_system", "ZFIN:curator" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#cumbo", "http://purl.obolibrary.org/obo/uberon/core#efo_slim", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], + "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#cumbo", "http://purl.obolibrary.org/obo/uberon/core#efo_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "neurological system", @@ -29759,7 +29697,7 @@ "val" : "nerve net", "xrefs" : [ "Wikipedia:Nerve_net" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "systema nervosum", "xrefs" : [ "Wikipedia:Nervous_system" ] @@ -29822,6 +29760,9 @@ "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_6040" + }, { + "pred" : "http://purl.obolibrary.org/obo/RO_0002175", + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" }, { "pred" : "http://purl.obolibrary.org/obo/UBPROP_0000001", "val" : "A regulatory system of the body that consists of neurons and neuroglial cells. The nervous system is divided into two parts, the central nervous system (CNS) and the peripheral nervous system (PNS). (Source: BioGlossary, www.Biology-Text.com)[TAO]" @@ -29857,13 +29798,13 @@ "val" : "The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the neural tube derivatives: the brain and spinal cord. In invertebrates it includes central ganglia plus nerve cord.", "xrefs" : [ "GO:0021551", "http://www.frontiersinzoology.com/content/7/1/29", "https://sourceforge.net/p/geneontology/ontology-requests/11422/" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#cumbo", "http://purl.obolibrary.org/obo/uberon/core#efo_slim", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], + "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#cumbo", "http://purl.obolibrary.org/obo/uberon/core#efo_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], "synonyms" : [ { "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003000", "pred" : "hasExactSynonym", "val" : "CNS" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "systema nervosum centrale", "xrefs" : [ "FMA:55675", "FMA:TA" ] @@ -29934,6 +29875,9 @@ "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099" + }, { + "pred" : "http://purl.obolibrary.org/obo/RO_0002175", + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" }, { "pred" : "http://purl.obolibrary.org/obo/UBPROP_0000001", "val" : "Part of the nervous system which includes the brain and spinal cord.[AAO]" @@ -30025,7 +29969,7 @@ "pred" : "hasRelatedSynonym", "val" : "presumptive central nervous system" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "tubus neuralis", "xrefs" : [ "Wikipedia:Neural_tube" ] @@ -30396,6 +30340,8 @@ "val" : "FMA:45615" }, { "val" : "MA:0000917" + }, { + "val" : "MESH:D041981" }, { "val" : "NCIT:C34082" }, { @@ -30578,7 +30524,7 @@ "val" : "vascular tree organ region", "xrefs" : [ "FMA:50722" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "vas sanguineum", "xrefs" : [ "Wikipedia:Blood_vessel" ] @@ -30933,6 +30879,8 @@ "val" : "MA:0002986" }, { "val" : "MAT:0000148" + }, { + "val" : "MESH:D013131" }, { "val" : "MIAA:0000148" }, { @@ -31152,7 +31100,7 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "cavitas thoracis", "xrefs" : [ "Wikipedia:Thoracic_cavity" ] @@ -31320,7 +31268,7 @@ "val" : "notocord", "xrefs" : [ "ZFA:0000135" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "notochorda", "xrefs" : [ "Wikipedia:Notochord" ] @@ -31433,7 +31381,7 @@ "pred" : "hasRelatedSynonym", "val" : "somitic mesoderm" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "somitus", "xrefs" : [ "Wikipedia:Somite" ] @@ -31529,7 +31477,7 @@ "val" : "NC", "xrefs" : [ "XAO:0000048" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "crista neuralis", "xrefs" : [ "Wikipedia:Neural_crest" ] @@ -31623,7 +31571,7 @@ "pred" : "hasExactSynonym", "val" : "neuroectoderm" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "epithelium tubi neuralis; neuroectoderma", "xrefs" : [ "Wikipedia:Neuroectoderm" ] @@ -31702,12 +31650,12 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#efo_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "medulla ossea", "xrefs" : [ "BTO:0000141", "FMA:9608" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "medulla ossium", "xrefs" : [ "BTO:0000141", "Wikipedia:Bone_marrow" ] @@ -32165,7 +32113,7 @@ "val" : "ectoblast", "xrefs" : [ "MP:0003886" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "epiblastus", "xrefs" : [ "Wikipedia:Epiblast" ] @@ -32424,7 +32372,7 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "lamina neuralis", "xrefs" : [ "Wikipedia:Neural_plate" ] @@ -32502,7 +32450,7 @@ "val" : "somitic mesoderm", "xrefs" : [ "ISBN:9780878932504" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "mesoderma paraxiale", "xrefs" : [ "Wikipedia:Paraxial_mesoderm" ] @@ -32578,7 +32526,7 @@ "val" : "lateral plate mesenchyme", "xrefs" : [ "EHDAA2:0000919" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "mesoderma laminae lateralis", "xrefs" : [ "Wikipedia:Lateral_plate_mesoderm" ] @@ -32699,7 +32647,7 @@ "val" : "sclerotomes", "xrefs" : [ "TAO:0001080" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "sclerotomus", "xrefs" : [ "Wikipedia:Sclerotome" ] @@ -32818,7 +32766,7 @@ "pred" : "hasExactSynonym", "val" : "portion of mesenchyme tissue" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "mesenchyma", "xrefs" : [ "Wikipedia:Mesenchyme" ] @@ -33461,7 +33409,7 @@ "val" : "An endothelium that lines the blood vasculature. Other endothelia may line lymph vessels, the heart.", "xrefs" : [ "https://orcid.org/0000-0002-6601-2165" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], + "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], "xrefs" : [ { "val" : "BTO:0000766" }, { @@ -33480,6 +33428,9 @@ "val" : "ZFA:0005257" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/RO_0002175", + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "uberon" } ] @@ -34359,7 +34310,7 @@ "val" : "basement membrane of connective tissue", "xrefs" : [ "FMA:63872" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "membrana basalis", "xrefs" : [ "Wikipedia:Basement_membrane" ] @@ -34431,7 +34382,7 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "skeleton axiale", "xrefs" : [ "Wikipedia:Axial_skeleton" ] @@ -35575,7 +35526,7 @@ "val" : "A subdivision of an anatomical system.", "xrefs" : [ "http://orcid.org/0000-0002-6601-2165" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#common_anatomy", "http://purl.obolibrary.org/obo/uberon/core#upper_level" ], + "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#common_anatomy", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#upper_level" ], "xrefs" : [ { "val" : "FBbt:00007330" }, { @@ -35592,6 +35543,9 @@ }, { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_4751" + }, { + "pred" : "http://purl.obolibrary.org/obo/RO_0002175", + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "uberon" @@ -35860,7 +35814,7 @@ "val" : "The region of the organism associated with the visceral organs.", "xrefs" : [ "AEO:0000103" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#non_informative" ], + "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#non_informative" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "body", @@ -35880,9 +35834,6 @@ "val" : "FMA:231424" } ], "basicPropertyValues" : [ { - "pred" : "http://purl.obolibrary.org/obo/RO_0002175", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" - }, { "pred" : "http://purl.obolibrary.org/obo/UBPROP_0000001", "val" : "Cardinal body part, which consists of a maximal set of diverse subclasses of organ and organ part spatially associated with the vertebral column and ribcage. Examples: There is only one body proper[FMA:231424]." }, { @@ -36314,8 +36265,10 @@ "val" : "OBSOLETE A relation between a cell and molecule or complex such that every instance of the cell has a high number of instances of that molecule expressed on the cell surface. For the formal definition, see Masci et al (PMID:19243617).", "xrefs" : [ "PMID:19243617" ] }, - "comments" : [ "Replaced with RO:0015015, see https://github.com/obophenotype/cell-ontology/issues/1481" ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/obophenotype/cell-ontology/issues/1481" + }, { "pred" : "http://purl.obolibrary.org/obo/IAO_0100001", "val" : "http://purl.obolibrary.org/obo/RO_0015015" } ], @@ -36330,8 +36283,10 @@ "val" : "OBSOLETE A relation between a cell and molecule or complex such that every instance of the cell has a low number of instances of that molecule expressed on the cell surface. For the formal definition, see Masci et al (PMID:19243617).", "xrefs" : [ "PMID:19243617" ] }, - "comments" : [ "Replaced with RO:0015016, see https://github.com/obophenotype/cell-ontology/issues/1481" ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/obophenotype/cell-ontology/issues/1481" + }, { "pred" : "http://purl.obolibrary.org/obo/IAO_0100001", "val" : "http://purl.obolibrary.org/obo/RO_0015016" } ], @@ -36561,13 +36516,12 @@ "lbl" : "transitively anteriorly connected to", "type" : "PROPERTY", "meta" : { - "definition" : { - "val" : ".", - "xrefs" : [ "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" ] - }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "uberon" + }, { + "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", + "val" : "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" } ] } }, { @@ -36575,13 +36529,12 @@ "lbl" : "transitively distally connected to", "type" : "PROPERTY", "meta" : { - "definition" : { - "val" : ".", - "xrefs" : [ "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" ] - }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "uberon" + }, { + "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", + "val" : "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" } ] } }, { @@ -36589,13 +36542,12 @@ "lbl" : "transitively proximally connected to", "type" : "PROPERTY", "meta" : { - "definition" : { - "val" : ".", - "xrefs" : [ "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" ] - }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "uberon" + }, { + "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", + "val" : "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" } ] } }, { @@ -37828,11 +37780,11 @@ }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000542", "pred" : "http://purl.obolibrary.org/obo/BFO_0000051", - "obj" : "http://purl.obolibrary.org/obo/CL_0017505" + "obj" : "http://purl.obolibrary.org/obo/GO_0000792" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000542", - "pred" : "http://purl.obolibrary.org/obo/BFO_0000051", - "obj" : "http://purl.obolibrary.org/obo/GO_0000792" + "pred" : "http://purl.obolibrary.org/obo/RO_0000053", + "obj" : "http://purl.obolibrary.org/obo/PATO_0040072" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000542", "pred" : "http://purl.obolibrary.org/obo/RO_0002202", @@ -37859,10 +37811,6 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0000547", "pred" : "http://purl.obolibrary.org/obo/BFO_0000051", "obj" : "http://purl.obolibrary.org/obo/CL_0017503" - }, { - "sub" : "http://purl.obolibrary.org/obo/CL_0000547", - "pred" : "http://purl.obolibrary.org/obo/BFO_0000051", - "obj" : "http://purl.obolibrary.org/obo/CL_0017505" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000547", "pred" : "http://purl.obolibrary.org/obo/BFO_0000051", @@ -37911,6 +37859,10 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0000547", "pred" : "http://purl.obolibrary.org/obo/CL_4030046", "obj" : "http://purl.obolibrary.org/obo/PR_000002978" + }, { + "sub" : "http://purl.obolibrary.org/obo/CL_0000547", + "pred" : "http://purl.obolibrary.org/obo/RO_0000053", + "obj" : "http://purl.obolibrary.org/obo/PATO_0040072" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000547", "pred" : "http://purl.obolibrary.org/obo/RO_0002104", @@ -39781,14 +39733,6 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0017504", "pred" : "http://purl.obolibrary.org/obo/RO_0000053", "obj" : "http://purl.obolibrary.org/obo/PATO_0070047" - }, { - "sub" : "http://purl.obolibrary.org/obo/CL_0017505", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/GO_0005634" - }, { - "sub" : "http://purl.obolibrary.org/obo/CL_0017505", - "pred" : "http://purl.obolibrary.org/obo/RO_0000053", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000586" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0017508", "pred" : "is_a", @@ -41057,7 +41001,7 @@ "obj" : "http://purl.obolibrary.org/obo/GO_0042060" }, { "sub" : "http://purl.obolibrary.org/obo/GO_0007596", - "pred" : "http://purl.obolibrary.org/obo/RO_0004008", + "pred" : "http://purl.obolibrary.org/obo/RO_0002588", "obj" : "http://purl.obolibrary.org/obo/UBERON_0010210" }, { "sub" : "http://purl.obolibrary.org/obo/GO_0007599", @@ -42178,7 +42122,7 @@ }, { "sub" : "http://purl.obolibrary.org/obo/GO_0045087", "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/GO_0098542" + "obj" : "http://purl.obolibrary.org/obo/GO_0140546" }, { "sub" : "http://purl.obolibrary.org/obo/GO_0045190", "pred" : "is_a", @@ -43239,6 +43183,10 @@ "sub" : "http://purl.obolibrary.org/obo/GO_0140352", "pred" : "http://purl.obolibrary.org/obo/RO_0002339", "obj" : "http://purl.obolibrary.org/obo/GO_0005576" + }, { + "sub" : "http://purl.obolibrary.org/obo/GO_0140546", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/GO_0098542" }, { "sub" : "http://purl.obolibrary.org/obo/GO_1901576", "pred" : "is_a", @@ -43475,18 +43423,6 @@ "sub" : "http://purl.obolibrary.org/obo/PATO_0000052", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/PATO_0000051" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0000068", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000001" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0000069", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000068" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0000117", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000051" }, { "sub" : "http://purl.obolibrary.org/obo/PATO_0000141", "pred" : "is_a", @@ -43503,18 +43439,6 @@ "sub" : "http://purl.obolibrary.org/obo/PATO_0000411", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/PATO_0000947" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0000461", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000068" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0000586", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000117" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0000586", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0002305" }, { "sub" : "http://purl.obolibrary.org/obo/PATO_0000947", "pred" : "is_a", @@ -43671,22 +43595,6 @@ "sub" : "http://purl.obolibrary.org/obo/PATO_0002299", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/PATO_0002078" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0002300", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000069" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0002300", - "pred" : "http://purl.obolibrary.org/obo/RO_0015007", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000461" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0002305", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0001241" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0002305", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0002300" }, { "sub" : "http://purl.obolibrary.org/obo/PATO_0002318", "pred" : "is_a", @@ -43707,6 +43615,10 @@ "sub" : "http://purl.obolibrary.org/obo/PATO_0015006", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/PATO_0000141" + }, { + "sub" : "http://purl.obolibrary.org/obo/PATO_0040072", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/PATO_0001396" }, { "sub" : "http://purl.obolibrary.org/obo/PATO_0070044", "pred" : "is_a", @@ -49257,15 +49169,15 @@ "restrictions" : [ { "propertyId" : "http://purl.obolibrary.org/obo/BFO_0000051", "fillerId" : "http://purl.obolibrary.org/obo/CL_0017500" - }, { - "propertyId" : "http://purl.obolibrary.org/obo/BFO_0000051", - "fillerId" : "http://purl.obolibrary.org/obo/CL_0017505" }, { "propertyId" : "http://purl.obolibrary.org/obo/BFO_0000051", "fillerId" : "http://purl.obolibrary.org/obo/GO_0000792" }, { "propertyId" : "http://purl.obolibrary.org/obo/RO_0000053", "fillerId" : "http://purl.obolibrary.org/obo/PATO_0001407" + }, { + "propertyId" : "http://purl.obolibrary.org/obo/RO_0000053", + "fillerId" : "http://purl.obolibrary.org/obo/PATO_0040072" } ] }, { "definedClassId" : "http://purl.obolibrary.org/obo/CL_0000547", @@ -49273,9 +49185,6 @@ "restrictions" : [ { "propertyId" : "http://purl.obolibrary.org/obo/BFO_0000051", "fillerId" : "http://purl.obolibrary.org/obo/CL_0017503" - }, { - "propertyId" : "http://purl.obolibrary.org/obo/BFO_0000051", - "fillerId" : "http://purl.obolibrary.org/obo/CL_0017505" }, { "propertyId" : "http://purl.obolibrary.org/obo/BFO_0000051", "fillerId" : "http://purl.obolibrary.org/obo/GO_0005730" @@ -49315,6 +49224,9 @@ }, { "propertyId" : "http://purl.obolibrary.org/obo/RO_0000053", "fillerId" : "http://purl.obolibrary.org/obo/PATO_0002505" + }, { + "propertyId" : "http://purl.obolibrary.org/obo/RO_0000053", + "fillerId" : "http://purl.obolibrary.org/obo/PATO_0040072" }, { "propertyId" : "http://purl.obolibrary.org/obo/RO_0002104", "fillerId" : "http://purl.obolibrary.org/obo/PR_000001945" @@ -50341,13 +50253,6 @@ "propertyId" : "http://purl.obolibrary.org/obo/RO_0000053", "fillerId" : "http://purl.obolibrary.org/obo/PATO_0070047" } ] - }, { - "definedClassId" : "http://purl.obolibrary.org/obo/CL_0017505", - "genusIds" : [ "http://purl.obolibrary.org/obo/GO_0005634" ], - "restrictions" : [ { - "propertyId" : "http://purl.obolibrary.org/obo/RO_0000053", - "fillerId" : "http://purl.obolibrary.org/obo/PATO_0000586" - } ] }, { "definedClassId" : "http://purl.obolibrary.org/obo/CL_1001610", "genusIds" : [ "http://purl.obolibrary.org/obo/CL_0000988" ], @@ -50765,7 +50670,7 @@ "definedClassId" : "http://purl.obolibrary.org/obo/GO_0007596", "genusIds" : [ "http://purl.obolibrary.org/obo/GO_0050817" ], "restrictions" : [ { - "propertyId" : "http://purl.obolibrary.org/obo/RO_0004008", + "propertyId" : "http://purl.obolibrary.org/obo/RO_0002588", "fillerId" : "http://purl.obolibrary.org/obo/UBERON_0010210" } ] }, { @@ -51777,27 +51682,6 @@ "propertyId" : "http://purl.obolibrary.org/obo/RO_0002213", "fillerId" : "http://purl.obolibrary.org/obo/GO_0048870" } ] - }, { - "definedClassId" : "http://purl.obolibrary.org/obo/PATO_0000586", - "genusIds" : [ "http://purl.obolibrary.org/obo/PATO_0000117" ], - "restrictions" : [ { - "propertyId" : "http://purl.obolibrary.org/obo/RO_0015007", - "fillerId" : "http://purl.obolibrary.org/obo/PATO_0000461" - } ] - }, { - "definedClassId" : "http://purl.obolibrary.org/obo/PATO_0002300", - "genusIds" : [ "http://purl.obolibrary.org/obo/PATO_0000001" ], - "restrictions" : [ { - "propertyId" : "http://purl.obolibrary.org/obo/RO_0015007", - "fillerId" : "http://purl.obolibrary.org/obo/PATO_0000461" - } ] - }, { - "definedClassId" : "http://purl.obolibrary.org/obo/PATO_0002305", - "genusIds" : [ "http://purl.obolibrary.org/obo/PATO_0001241" ], - "restrictions" : [ { - "propertyId" : "http://purl.obolibrary.org/obo/RO_0015007", - "fillerId" : "http://purl.obolibrary.org/obo/PATO_0000461" - } ] }, { "definedClassId" : "http://purl.obolibrary.org/obo/PR_000029032", "genusIds" : [ "http://purl.obolibrary.org/obo/PR_000000001" ], diff --git a/src/ontology/subsets/blood_and_immune_upper_slim.obo b/src/ontology/subsets/blood_and_immune_upper_slim.obo index dfabdc25d..35057603f 100644 --- a/src/ontology/subsets/blood_and_immune_upper_slim.obo +++ b/src/ontology/subsets/blood_and_immune_upper_slim.obo @@ -1,5 +1,5 @@ format-version: 1.2 -data-version: cl/releases/2024-01-04/subsets/blood_and_immune_upper_slim.owl +data-version: cl/releases/2024-02-13/subsets/blood_and_immune_upper_slim.owl subsetdef: abnormal_slim "" subsetdef: added_for_HCA "" subsetdef: attribute_slim "" @@ -31,6 +31,7 @@ subsetdef: goslim_mouse "" subsetdef: goslim_pir "" subsetdef: goslim_plant "" subsetdef: goslim_pombe "" +subsetdef: goslim_prokaryote "" subsetdef: goslim_synapse "" subsetdef: goslim_yeast "" subsetdef: grouping_class "" @@ -49,7 +50,6 @@ subsetdef: non_informative "" subsetdef: organ_slim "" subsetdef: pheno_slim "" subsetdef: phenotype_rcn "" -subsetdef: prokaryote_subset "" subsetdef: ro-eco "" subsetdef: RO:0002259 "" subsetdef: scalar_slim "" @@ -62,7 +62,6 @@ subsetdef: vertebrate_core "" synonymtypedef: blast_name "" synonymtypedef: COMPARATIVE_PREFERRED "" synonymtypedef: DEPRECATED "" -synonymtypedef: DUBIOUS "" synonymtypedef: equivalent_name "" synonymtypedef: genbank_common_name "" synonymtypedef: Gene-based "" @@ -71,13 +70,14 @@ synonymtypedef: HUMAN_PREFERRED "" synonymtypedef: HUMAN_PREFERRED "preferred term when talking about an instance of this class in Homo sapiens" synonymtypedef: in_part "" synonymtypedef: INCONSISTENT "" -synonymtypedef: LATIN "" synonymtypedef: LATIN "latin term" synonymtypedef: MISSPELLING "a mis-spelling that is in common use and thus recorded" synonymtypedef: NON_MAMMAL "" synonymtypedef: OMO:0003000 "abbreviation" +synonymtypedef: OMO:0003002 "" synonymtypedef: OMO:0003003 "" synonymtypedef: OMO:0003004 "plural form" +synonymtypedef: OMO:0003011 "" synonymtypedef: PENDING_REVIEW "" synonymtypedef: PLURAL "plural term" synonymtypedef: PRO-short-label "" @@ -88,7 +88,7 @@ synonymtypedef: synonym "" synonymtypedef: SYSTEMATIC "" synonymtypedef: systematic_synonym "" ontology: cl/subsets/blood_and_immune_upper_slim -property_value: owl:versionInfo "2024-01-04" xsd:string +property_value: owl:versionInfo "2024-02-13" xsd:string [Term] id: BFO:0000002 @@ -144,6 +144,7 @@ id: CL:0000000 name: cell def: "A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane." [CARO:mah] comment: The definition of cell is intended to represent all cells, and thus a cell is defined as a material entity and not an anatomical structure, which implies that it is part of an organism (or the entirety of one). +subset: cellxgene_subset subset: ubprop:upper_level xref: CALOHA:TS-2035 xref: FBbt:00007002 @@ -171,6 +172,7 @@ id: CL:0000034 name: stem cell def: "A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells." [GOC:tfm, MESH:D013234] comment: This term applies to metazoan. For plant stem cells, consider using PO:0004011 ‘initial cell’ or its parent PO:0004010 ‘meristematic cell’. +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "animal stem cell" EXACT [] @@ -189,6 +191,7 @@ name: hematopoietic stem cell def: "A stem cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system. Hematopoietic stem cells lack cell markers of effector cells (lin-negative). Lin-negative is defined by lacking one or more of the following cell surface markers: CD2, CD3 epsilon, CD4, CD5 ,CD8 alpha chain, CD11b, CD14, CD19, CD20, CD56, ly6G, ter119." [GOC:add, GOC:dsd, GOC:tfm, http://en.wikipedia.org/wiki/Hematopoietic_stem_cell, PMID:19022770] comment: Markers differ between species, and two sets of markers have been described for mice. HSCs are reportedly CD34-positive, CD45-positive, CD48-negative, CD150-positive, CD133-positive, and CD244-negative. subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "blood forming stem cell" EXACT [] synonym: "colony forming unit hematopoietic" RELATED [] @@ -238,6 +241,7 @@ id: CL:0000038 name: erythroid progenitor cell def: "A progenitor cell committed to the erythroid lineage." [GOC:add, ISBN:0721601464] subset: blood_and_immune_upper_slim +subset: cellxgene_subset synonym: "BFU-E" RELATED OMO:0003000 [] synonym: "blast forming unit erythroid" RELATED [] synonym: "burst forming unit erythroid" RELATED [] @@ -295,6 +299,7 @@ id: CL:0000049 name: common myeloid progenitor def: "A progenitor cell committed to myeloid lineage, including the megakaryocyte and erythroid lineages." [GOC:add, ISBN:0878932437, MESH:D023461] comment: This cell type is intended to be compatible with any vertebrate common myeloid progenitor. For mammalian CMP known to be CD34-positive, please use the term 'common myeloid progenitor, CD34-positive' (CL_0001059). +subset: cellxgene_subset subset: human_reference_atlas synonym: "CFU-GEMM" RELATED OMO:0003000 [ISBN:0878932437] synonym: "CFU-S" RELATED OMO:0003000 [ISBN:0878932437] @@ -316,6 +321,7 @@ id: CL:0000050 name: megakaryocyte-erythroid progenitor cell def: "A progenitor cell committed to the megakaryocyte and erythroid lineages." [GOC:add, GOC:dsd, GOC:tfm, http://en.wikipedia.org/wiki/Megakaryocyte-erythroid_progenitor_cell, MESH:D055015, PMID:16647566] comment: MEPs are reportedly CD19-negative, CD34-negative, CD45RA-negative, CD110-positive, CD117-positive, and SCA1-negative and reportedly express the transcription factors GATA-1 and NF-E2. +subset: cellxgene_subset subset: human_reference_atlas synonym: "CFU-EM" EXACT [] synonym: "CFU-MegE" EXACT [] @@ -341,6 +347,7 @@ id: CL:0000051 name: common lymphoid progenitor def: "A oligopotent progenitor cell committed to the lymphoid lineage." [GOC:add, GOC:dsd, GOC:tfm, PMID:10407577, PMID:16551251] comment: CLP are CD7-positive, CD10-positive, CD19-negative, CD34-positive, CD45RA-positive, CD79a-negative, CD127-positive, AA4.1-positive, RAG-negative, Sca-1-low, sIgM-negative, sIgD-negative, TdT-negative, Vpre-B-negative, and pre-BCR-negative. Expression of transcription factors include E2A-positive, EBF-positive, Ikaros-negative, PU.1-negative, and Pax5-negative. +subset: cellxgene_subset subset: human_reference_atlas synonym: "CLP" RELATED OMO:0003000 [] synonym: "committed lymphopoietic stem cell" RELATED [] @@ -372,6 +379,7 @@ id: CL:0000055 name: non-terminally differentiated cell def: "A precursor cell with a limited number of potential fates." [SANBI:mhl] comment: define using PATO mulit-potent or oligopotent? +subset: cellxgene_subset synonym: "blast cell" EXACT [] xref: BTO:0000125 xref: FMA:84782 @@ -393,6 +401,7 @@ id: CL:0000057 name: fibroblast def: "A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped." [http://en.wikipedia.org/wiki/Fibroblast, ISBN:0517223651, MESH:D005347] comment: These cells may be vimentin-positive, fibronectin-positive, fsp1-positive, MMP-1-positive, collagen I-positive, collagen III-positive, and alpha-SMA-negative. +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas xref: BTO:0000452 @@ -408,6 +417,7 @@ relationship: present_in_taxon NCBITaxon:9606 id: CL:0000066 name: epithelial cell def: "A cell that is usually found in a two-dimensional sheet with a free surface. The cell has a cytoskeleton that allows for tight cell to cell contact and for cell polarity where apical part is directed towards the lumen and the basal part to the basal lamina." [FB:ma, GOC:tfm, MESH:D004847] +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "epitheliocyte" EXACT [] @@ -427,6 +437,7 @@ property_value: depiction "https://www.swissbiopics.org/api/image/Epithelial_cel id: CL:0000071 name: blood vessel endothelial cell def: "An endothelial cell that lines the vasculature." [GOC:tfm] +subset: cellxgene_subset subset: human_reference_atlas synonym: "cuboidal endothelial cell of vascular tree" EXACT [] is_a: CL:0000076 {is_inferred="true"} ! squamous epithelial cell @@ -440,6 +451,7 @@ relationship: present_in_taxon NCBITaxon:9606 [Term] id: CL:0000076 name: squamous epithelial cell +subset: cellxgene_subset xref: CALOHA:TS-1249 is_a: CL:0000066 ! epithelial cell @@ -456,6 +468,7 @@ relationship: part_of UBERON:0000179 ! haemolymphatic fluid id: CL:0000081 name: blood cell def: "A cell found predominately in the blood." [GOC:add, GOC:tfm] +subset: cellxgene_subset subset: general_cell_types_upper_slim xref: FMA:62844 xref: MESH:D001773 @@ -468,6 +481,7 @@ relationship: capable_of GO:0008015 ! blood circulation id: CL:0000084 name: T cell def: "A type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex." [GOC:add, GOC:tfm, ISBN:0781735149] +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "immature T cell" RELATED [] @@ -493,6 +507,7 @@ id: CL:0000092 name: osteoclast def: "A specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue, which typically differentiates from monocytes. This cell has the following markers: tartrate-resistant acid phosphatase type 5-positive, PU.1-positive, c-fos-positive, nuclear factor NF-kappa-B p100 subunit-positive, tumor necrosis factor receptor superfamily member 11A-positive and macrophage colony-stimulating factor 1 receptor-positive." [GO_REF:0000031, GOC:add, GOC:tfm, ISBN:0781735149, PMID:10428500, PMID:15055519, PMID:17380158] comment: Morphology: Highly vesicular; markers: Surface: RANK, cFMS (MCSF receptor); Secreted: cathepsin K and TRAP (tartate resistant acid phosphatase); transcription factors: PU.1, cFOS, MITF, NFkB (p52); role or process: tissue remodelling: bone resorption; lineage: hematopoietic, myeloid. +subset: cellxgene_subset synonym: "chondroclast" RELATED [] xref: BTO:0000968 xref: CALOHA:TS-0721 @@ -526,6 +541,7 @@ relationship: RO:0002104 PR:000002062 ! has plasma membrane part macrophage colo id: CL:0000094 name: granulocyte def: "A leukocyte with abundant granules in the cytoplasm." [GOC:amm, GOC:tfm, http://en.wikipedia.org/wiki/Granulocyte, MESH:D006098] +subset: cellxgene_subset subset: human_reference_atlas synonym: "granular leucocyte" EXACT [] synonym: "granular leukocyte" EXACT [] @@ -563,6 +579,7 @@ name: mast cell def: "A cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation. Progenitors leave bone marrow and mature in connective and mucosal tissue. Mature mast cells are found in all tissues, except the bloodstream. Their phenotype is CD117-high, CD123-negative, CD193-positive, CD200R3-positive, and FceRI-high. Stem-cell factor (KIT-ligand; SCF) is the main controlling signal of their survival and development." [GOC:add, GOC:dsd, GOC:tfm, ISBN:068340007X, MESH:D008407, PMCID:PMC1312421, PMCID:PMC2855166, PMID:15153310, PMID:16455980, PMID:19671378, PMID:212366338, PMID:9354811] comment: Mast cells are generally integrin beta-7-negative and positive for TLR2, TLR3, TLR4, TLR5, TLR7, TLR9, C3aR, C5aR, CR3, CR4, VEGF, FGF2, and renin. They can express MHC Class I and II on their surface. Activated murine mast cells (IgE+Antigen) were capable of expressing the following co-stimulatory molecules: CD95 (Fas), CD120b, CD137 (4-1BB), CD153 (CD30L), CD154 (CD40L), GITR, ICOSL, OX40L, PD-L1, and PD-L2. Note that there was some mouse strain variation. Mast cells have also been demonstrated to produce bFGF, CCL2, CCL4, CCL5, CCL11, CCL20, CXCL2, CXCL8, CXCL10, GM-CSF, IFN-gamma, IL-1, IL-2, IL-3, IL-8, IL-10, IL-11, IL-12, IL-13, IL-16, IL-25, IL-18, MIP-1, prostaglandin D2, SCF, TGF-beta, TNF-alpha, TSLP, VEGF, and XCL1. They express the transcription factors Transcription factors AP-1, GATA1, MITF, Notch2, PIAS3, PU.1, and STAT5. subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "histaminocyte" EXACT [] synonym: "labrocyte" EXACT [ISBN:0721601464] @@ -606,6 +623,7 @@ relationship: RO:0015015 PR:000007431 ! has high plasma membrane amount high aff id: CL:0000113 name: mononuclear phagocyte def: "A vertebrate phagocyte with a single nucleus." [GOC:add, GOC:tfm, ISBN:0781735149] +subset: cellxgene_subset subset: human_reference_atlas xref: BTO:0001433 is_a: CL:0000518 {is_inferred="true"} ! phagocyte (sensu Vertebrata) @@ -619,6 +637,7 @@ id: CL:0000115 name: endothelial cell def: "An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal. In mammals, endothelial cell has vimentin filaments and is derived from the mesoderm." [GOC:tfm, http://en.wikipedia.org/wiki/Endothelial_cell, https://sourceforge.net/tracker/?func=detail&atid=440764&aid=3364936&group_id=36855, MESH:D042783, PMID:21275341] comment: From FMA: 9.07.2001: Endothelial cell has always been classified as a kind of epithelial cell, specifically a squamous cell but that is not true. First, endothelial cell can either be squamous or cuboidal (e.g. high-endothelial cell) and secondly, it has different embryological derivation (mesodermal) than a true epithelial cell (ectodermal and endodermal). The basis for present classification is the fact that it comprises the outermost layer or lining of anatomical structures (location-based) but a better structural basis for the differentia is the cytoskeleton of the cell. Endothelial cell has vimentin filaments while an epithelial cell has keratin filaments. [Onard]. +subset: cellxgene_subset subset: human_reference_atlas synonym: "endotheliocyte" EXACT [] xref: BTO:0001176 @@ -640,6 +659,7 @@ id: CL:0000134 name: mesenchymal stem cell def: "A connective tissue cell that normally gives rise to other cells that are organized as three-dimensional masses. In humans, this cell type is CD73-positive, CD90-positive, CD105-positive, CD45-negative, CD34-negative, and MHCII-negative. They may further differentiate into osteoblasts, adipocytes, myocytes, neurons, or chondroblasts in vitro. Originally described as residing in the bone marrow, this cell type is now known to reside in many, if not all, adult organs." [FB:ma, GOC:dsd, http://en.wikipedia.org/wiki/Mesenchymal_stem_cell, http://www.copewithcytokines.de/cope.cgi?key=mesenchymal%20stem%20cells, PMCID:PMC2613570, PMID:10102814, PMID:16923606, PMID:17986482, PMID:19960544] comment: Many but not all mesenchymal cells derive from the mesoderm. MSCs are reportedly CD3-negative, CD4-negative, CD5-negative, CD8-negative, CD11a-negative, CD11b-negative, CD14-negative, CD19-negative, CD29-positive, CD31-negative, CD34-negative, CD38-negative, CD40-negative, CD44-positive, CD45-negative, CD49-positive, CD54-positive, CD66b-negative, CD79a-negative, CD80-negative, CD102-positive, CD106-positive, CD117-positive, CD121a-positive, CD121b-positive, CD123-positive, CD124-positive, CD133-negative, CD146-positive, CD166-positive, CD271-positive, B220-negative, Gr1-negative, MHCI-positive, MHCII-negative, SSEA4-negative, sca1-positive, Ter119-negative, and glycophorin A-negative. Cultured MSCs are capable of producing stem cell factor, IL7, IL8, IL11, TGF-beta, cofilin, galectin-1, laminin-receptor 1, cyclophilin A, and MMP-2. +subset: cellxgene_subset synonym: "BMSC" RELATED OMO:0003000 [] synonym: "bone marrow stromal cells" NARROW [] synonym: "CFU-F" RELATED OMO:0003000 [] @@ -665,6 +685,7 @@ name: professional antigen presenting cell def: "A cell capable of processing and presenting lipid and protein antigens to T cells in order to initiate an immune response." [GOC:add, ISBN:0781735149] comment: Note change of name; nearly all somatic cells can present antigens to T cells via MHC Class I complexes leading to effector responses, but professional antigen presenting cells constitutively express MHC Class II as well as costimulatory molecules, and thus can initiate immune responses via T cells. subset: blood_and_immune_upper_slim +subset: cellxgene_subset synonym: "APC" RELATED OMO:0003000 [] is_a: CL:0000738 ! leukocyte intersection_of: CL:0000738 ! leukocyte @@ -675,6 +696,7 @@ relationship: capable_of GO:0002504 ! antigen processing and presentation of pep id: CL:0000151 name: secretory cell def: "A cell that specializes in controlled release of one or more substances." [GOC:tfm, ISBN:0721662544] +subset: cellxgene_subset xref: BTO:0003659 xref: FMA:86916 is_a: CL:0000000 ! cell @@ -686,12 +708,14 @@ relationship: capable_of GO:0032940 ! secretion by cell id: CL:0000183 name: contractile cell def: "A cell whose primary function is to shorten." [FB:ma] +subset: cellxgene_subset is_a: CL:0000000 ! cell [Term] id: CL:0000187 name: muscle cell def: "A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns." [MESH:D032342] +subset: cellxgene_subset synonym: "muscle fiber" EXACT [] synonym: "myocyte" EXACT [] xref: BTO:0000888 @@ -746,6 +770,7 @@ relationship: part_of UBERON:0000924 ! ectoderm id: CL:0000222 name: mesodermal cell def: "A cell of the middle germ layer of the embryo." [MESH:D008648] +subset: cellxgene_subset synonym: "mesoblast" EXACT [] synonym: "mesoderm cell" EXACT [] xref: FMA:72554 @@ -801,6 +826,7 @@ id: CL:0000232 name: erythrocyte def: "A red blood cell. In mammals, mature erythrocytes are biconcave disks containing hemoglobin whose function is to transport oxygen." [GOC:tfm, MESH:D004912] subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "RBC" EXACT [] synonym: "red blood cell" EXACT [] @@ -828,6 +854,7 @@ name: platelet def: "A non-nucleated disk-shaped cell formed by extrusion from megakaryocytes, found in the blood of all mammals, and mainly involved in blood coagulation." [GOC:add, GOC:dsd, GOC:tfm, http://en.wikipedia.org/wiki/Platelet, MESH:D001792, PMID:11110672, PMID:16987572, PMID:17204662, PMID:17479180, PMID:20414831] comment: Platelets are reportedly CCR1-positive, CCR2-negative, CCR3-positive, CCR4-positive, CCR5-negative, CCR6-negative, CCR7-negative, CCR8-negative, CCR9-negative, CCR10-negative, CD16-positive, CD23-positive, CD32-positive, CD40-positive, CD41-positive CD42-positive, CD61-positive, CD62P-positive, CD64-positive, CD89-positive, CD102-positive, CD147-positive (activated platelets), CD154-positive (activated platelets), CD162-positive, CD209, CD282-positive, CD284-positive, CD289-positive, CD181-negative, CD182-negative, CD183-negative, CD184-positive, CLEC2-positive, GPVI-positive, JAMC-positive, PAR1-positive, PAR2-negative, PAR3-positive, PAR4-positive, TSP1-positive, and TXA2R-positive. Platelets can reportedly produce CCL2, CCL3, CCL5, CCL7, CCL17, CD40L, CXCL1, CXCL4, CXCL4L1, CXCL5, CXCL7, CXCL8, CXCL12, EGF, factor V, factor VII, factor XI, factor XIII, bFGF, histamine, IGF-1, IL-1beta, PAI-1, PDGF, plasminogen, protein S, serotonin, TGF-beta, TFPI, VEGF, and vWF. subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "anucleate thrombocyte" EXACT [] synonym: "blood platelet" EXACT [] @@ -848,6 +875,7 @@ relationship: present_in_taxon NCBITaxon:9606 id: CL:0000234 name: phagocyte def: "Any cell capable of ingesting particulate matter via phagocytosis." [GOC:add, ISBN:0721601464] +subset: cellxgene_subset xref: BTO:0001044 xref: FMA:83806 xref: MESH:D010586 @@ -864,6 +892,7 @@ name: macrophage def: "A mononuclear phagocyte present in variety of tissues, typically differentiated from monocytes, capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells." [GO_REF:0000031, GOC:add, GOC:tfm, PMID:16213494, PMID:1919437] comment: Morphology: Diameter 30_M-80 _M, abundant cytoplasm, low N/C ratio, eccentric nucleus. Irregular shape with pseudopods, highly adhesive. Contain vacuoles and phagosomes, may contain azurophilic granules; markers: Mouse & Human: CD68, in most cases CD11b. Mouse: in most cases F4/80+; role or process: immune, antigen presentation, & tissue remodelling; lineage: hematopoietic, myeloid. subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "histiocyte" EXACT [] @@ -888,6 +917,7 @@ id: CL:0000236 name: B cell def: "A lymphocyte of B lineage that is capable of B cell mediated immunity." [GO_REF:0000031, GOC:add, GOC:tfm, ISBN:0781735149] subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "B lymphocyte" EXACT [] @@ -907,6 +937,7 @@ relationship: present_in_taxon NCBITaxon:9606 [Term] id: CL:0000255 name: eukaryotic cell +subset: cellxgene_subset xref: MESH:D005057 is_a: CL:0000000 ! cell intersection_of: CL:0000000 ! cell @@ -981,6 +1012,7 @@ is_a: CL:0000211 ! electrically active cell id: CL:0000451 name: dendritic cell def: "A cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation. These cells are lineage negative (CD3-negative, CD19-negative, CD34-negative, and CD56-negative)." [GOC:add, ISBN:0781735149] +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "interdigitating cell" RELATED [] @@ -1050,6 +1082,7 @@ id: CL:0000540 name: neuron def: "The basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system." [http://en.wikipedia.org/wiki/Neuron, MESH:D009474] comment: These cells are also reportedly CD4-negative and CD200-positive. They are also capable of producing CD40L and IFN-gamma. +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "nerve cell" EXACT [] @@ -1071,6 +1104,7 @@ id: CL:0000542 name: lymphocyte def: "A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin." [GOC:add, ISBN:0683073696, ISBN:0781735149] comment: Editors note: consider adding taxon constraint to vertebrata (PMID:18025161) +subset: cellxgene_subset subset: human_reference_atlas xref: BTO:0000775 xref: CALOHA:TS-0583 @@ -1081,13 +1115,13 @@ is_a: CL:0000842 ! mononuclear cell is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000738 ! leukocyte intersection_of: bearer_of PATO:0001407 ! mononucleate +intersection_of: bearer_of PATO:0040072 ! high nuclear/cytoplasmic ratio intersection_of: has_part CL:0017500 ! neutrophillic cytoplasm -intersection_of: has_part CL:0017505 ! increased nucleus size intersection_of: has_part GO:0000792 ! heterochromatin disjoint_from: CL:0000766 ! myeloid leukocyte +relationship: bearer_of PATO:0040072 ! high nuclear/cytoplasmic ratio relationship: develops_from CL:0000051 ! common lymphoid progenitor relationship: has_part CL:0017500 ! neutrophillic cytoplasm -relationship: has_part CL:0017505 ! increased nucleus size relationship: has_part GO:0000792 ! heterochromatin relationship: present_in_taxon NCBITaxon:9606 @@ -1096,6 +1130,7 @@ id: CL:0000547 name: proerythroblast def: "An immature, nucleated erythrocyte occupying the stage of erythropoeisis that follows formation of erythroid progenitor cells. This cell is CD71-positive, has both a nucleus and a nucleolus, and lacks hematopoeitic lineage markers." [ISBN:0721601464, PMID:1638021] subset: blood_and_immune_upper_slim +subset: cellxgene_subset synonym: "pronormoblast" RELATED [] synonym: "rubriblast" EXACT [ISBN:0721601464] xref: FMA:83518 @@ -1104,6 +1139,7 @@ is_a: CL:0002242 ! nucleate cell is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000764 ! erythroid lineage cell intersection_of: bearer_of PATO:0002505 ! nucleated +intersection_of: bearer_of PATO:0040072 ! high nuclear/cytoplasmic ratio intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M @@ -1116,9 +1152,9 @@ intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell sur intersection_of: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule intersection_of: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G intersection_of: has_part CL:0017503 ! basophilic cytoplasm -intersection_of: has_part CL:0017505 ! increased nucleus size intersection_of: has_part GO:0005730 ! nucleolus intersection_of: RO:0002104 PR:000001945 ! has plasma membrane part transferrin receptor protein 1 +relationship: bearer_of PATO:0040072 ! high nuclear/cytoplasmic ratio relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M @@ -1132,7 +1168,6 @@ relationship: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule relationship: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G relationship: develops_from CL:0000038 ! erythroid progenitor cell relationship: has_part CL:0017503 ! basophilic cytoplasm -relationship: has_part CL:0017505 ! increased nucleus size relationship: has_part GO:0005730 ! nucleolus relationship: RO:0002104 PR:000001945 ! has plasma membrane part transferrin receptor protein 1 @@ -1200,6 +1235,7 @@ id: CL:0000553 name: megakaryocyte progenitor cell def: "The earliest cytologically identifiable precursor in the thrombocytic series. This cell is capable of endomitosis and lacks expression of hematopoieitic lineage markers (lin-negative)." [GOC:dsd, GOC:tfm, ISBN:0721601464] comment: Lineage negative is described here as CD2-negative, CD3-negative, CD4-negative, CD5-negative, CD8a-negative, CD14-negative, CD19-negative, CD20-negative, CD56-negative, Ly6g-negative, and Ter119-negative. +subset: cellxgene_subset subset: human_reference_atlas synonym: "CFU-Meg" EXACT [PMID:11722431, PMID:12482498] synonym: "colony-forming unit-megakaryocyte" EXACT [] @@ -1255,6 +1291,7 @@ name: megakaryocyte def: "A large hematopoietic cell (50 to 100 micron) with a lobated nucleus. Once mature, this cell undergoes multiple rounds of endomitosis and cytoplasmic restructuring to allow platelet formation and release." [http://en.wikipedia.org/wiki/Megakaryocyte, ISBN:0721601464, MESH:D008533, PMID:31043076] comment: Megakaryocytes are reportedly CD181-positive and CD182-positive. subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "megacaryocyte" EXACT [] synonym: "megalocaryocyte" EXACT [] @@ -1273,6 +1310,7 @@ id: CL:0000557 name: granulocyte monocyte progenitor cell def: "A hematopoietic progenitor cell that is committed to the granulocyte and monocyte lineages. These cells are CD123-positive, and do not express Gata1 or Gata2 but do express C/EBPa, and Pu.1." [GO_REF:0000031, GOC:amm, GOC:dsd, GOC:tfm, http://en.wikipedia.org/wiki/CFU-GM, http://www.copewithcytokines.de, ISBN:0721601464, MESH:D055014, PMCID:PMC2213186, PMCID:PMC548021, PMID:16551251, PMID:16647566] comment: Originally described in the dendritic cell ontology (DC_CL:0000042)(PMID:19243617). GMPs are reportedly CD16-positive, CD32-positive, CD34-positive, CD38-positive, CD45RA-positive, CD110-negative, CD117-positive, CD123-positive, and SCA1-negative. +subset: cellxgene_subset subset: human_reference_atlas synonym: "CFU-C , Colony forming unit in culture" BROAD [http://www.copewithcytokines.de] synonym: "CFU-GM" RELATED OMO:0003000 [ISBN:0721601464, PMCID:PMC2213186, PMCID:PMC548021] @@ -1309,6 +1347,7 @@ id: CL:0000558 name: reticulocyte def: "An immature erythrocyte that changes the protein composition of its plasma membrane by exosome formation and extrusion. The types of protein removed differ between species though removal of the transferrin receptor is apparent in mammals and birds." [GOC:add, GOC:tfm, PMID:15946868, PMID:2037622] subset: blood_and_immune_upper_slim +subset: cellxgene_subset xref: BTO:0001173 xref: CALOHA:TS-0864 xref: MESH:D012156 @@ -1348,6 +1387,7 @@ id: CL:0000559 name: promonocyte def: "A precursor in the monocytic series, being a cell intermediate in development between the monoblast and monocyte. This cell is CD11b-positive and has fine azurophil granules." [GOC:tfm, ISBN:0721601464] comment: Morphology: Mononuclear cell, diameter 14-18 _M, fine azurophilic granules; markers: CD11b (shared with many other myeloid cells); location: Adult: bone marrow; Fetal: Liver, Yolk Sac; role or process: hematopoiesis, monocyte development; lineage: hematopoietic, myeloid. +subset: cellxgene_subset subset: human_reference_atlas xref: BTO:0004657 xref: FMA:83551 @@ -1388,6 +1428,7 @@ name: monocyte def: "Myeloid mononuclear recirculating leukocyte that can act as a precursor of tissue macrophages, osteoclasts and some populations of tissue dendritic cells." [GO_REF:0000031, MESH:D009000] comment: Morphology: Mononuclear cell, diameter, 14 to 20 _M, N/C ratio 2:1-1:1. Nucleus may appear in variety of shapes: round, kidney, lobulated, or convoluted. Fine azurophilic granules present; markers: CD11b (shared with other myeloid cells), human: CD14, mouse: F4/80-mid,GR1-low; location: Blood, but can be recruited into tissues; role or process: immune & tissue remodelling; lineage: hematopoietic, myeloid. subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas xref: BTO:0000876 @@ -1435,11 +1476,12 @@ relationship: participates_in GO:0002544 ! chronic inflammatory response id: CL:0000680 name: muscle precursor cell def: "A non-terminally differentiated cell that is capable of developing into a muscle cell." [GOC:add] +subset: cellxgene_subset is_a: CL:0000055 ! non-terminally differentiated cell intersection_of: CL:0011115 ! precursor cell -intersection_of: RO:0002203 CL:0000187 ! develops into muscle cell +intersection_of: develops_into CL:0000187 ! muscle cell relationship: develops_from CL:0000222 ! mesodermal cell -relationship: RO:0002203 CL:0000187 ! develops into muscle cell +relationship: develops_into CL:0000187 ! muscle cell [Term] id: CL:0000723 @@ -1456,6 +1498,7 @@ relationship: capable_of GO:0048103 ! somatic stem cell division id: CL:0000738 name: leukocyte def: "An achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue." [GOC:add, GOC:tfm, ISBN:978-0-323-05290-0] +subset: cellxgene_subset subset: human_reference_atlas synonym: "immune cell" RELATED [] synonym: "leucocyte" EXACT [] @@ -1496,6 +1539,7 @@ relationship: develops_from CL:0000828 ! thromboblast id: CL:0000763 name: myeloid cell def: "A cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage." [GOC:add] +subset: cellxgene_subset xref: BTO:0001441 xref: CALOHA:TS-0647 xref: MESH:D022423 @@ -1509,6 +1553,7 @@ id: CL:0000764 name: erythroid lineage cell def: "A immature or mature cell in the lineage leading to and including erythrocytes." [GOC:add, GOC:tfm] comment: Note that in FMA erythropoietic cells are types of nucleated erythrocytes and thus don't include erythrocytes. +subset: cellxgene_subset subset: human_reference_atlas synonym: "erythropoietic cell" EXACT [] xref: CALOHA:TS-0290 @@ -1522,6 +1567,7 @@ id: CL:0000765 name: erythroblast def: "A nucleated precursor of an erythrocyte that lacks hematopoietic lineage markers." [GOC:add, ISBN:0721601464, PMID:18174176] subset: blood_and_immune_upper_slim +subset: cellxgene_subset synonym: "normoblast" EXACT [] xref: BTO:0001571 xref: CALOHA:TS-0289 @@ -1564,6 +1610,7 @@ relationship: has_part GO:0005634 ! nucleus id: CL:0000766 name: myeloid leukocyte def: "A cell of the monocyte, granulocyte, or mast cell lineage." [GOC:add] +subset: cellxgene_subset is_a: CL:0000738 {is_inferred="true"} ! leukocyte is_a: CL:0000763 ! myeloid cell intersection_of: CL:0000738 ! leukocyte @@ -1575,6 +1622,7 @@ name: basophil def: "Any of the immature or mature forms of a granular leukocyte that in its mature form has an irregularly shaped, pale-staining nucleus that is partially constricted into two lobes, and with cytoplasm that contains coarse, bluish-black granules of variable size. Basophils contain vasoactive amines such as histamine and serotonin, which are released on appropriate stimulation. A basophil is CD123-positive, CD193-positive, CD203c-positive, and FceRIa-positive." [GOC:add, GOC:amm, GOC:dsd, GOC:tfm, ISBN:0721601464, MESH:D001491, PMCID:PMC2626675, PMID:11927641, PMID:19741522, PMID:21236338, PMID:9933081] comment: Matures in the bone marrow and account for <1% of leukocytes in the peripheral blood, spleen, and bone marrow. Basophils are described as being CD11a-positive, CD11b-positive, CD13-positive, CD15-positive, CD18-positive, CD21-positive, CD25-positive, CD29-positive, CD35-positive, CD40-positive, CD40L-positive, CD44-positive, CD45R-negative, CD46-positive, CD49a-positive, CD49b-positive, CD49d-positive, CD55-positive, CD59-positive, CD62L-positive, CD63-positive, CD69-positive, CD90-negative, CD116-positive, CD117-negative, CD124-positive, CD125-positive, CD131-positive, CD161-positive, CD184-positive, CD191-positive, CD192-positive, CD197-positive, CD200R3-positive, CD218-positive, CD282-positive, CD284-positive, CD289-positive, CD290-positive, CD294-positive, natural killer cell receptor 2B4-positive, smad1-positive, CD3-negative, CD4-negative, CD7-negative, CD8-negative, CD14-negative, CD15-negative, CD16-negative, CD19-negative, CD20-negative, CD34-negative, CD36-negative, CD45R-negative, CD56-negative, CD57-negative, CD235a-negative, and GR1-negative. Transcription factors- GATA1-positive, PU.1-positive. subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "basophilic leucocyte" EXACT [] synonym: "basophilic leukocyte" EXACT [] @@ -1603,6 +1651,7 @@ name: eosinophil def: "Any of the immature or mature forms of a granular leukocyte with a nucleus that usually has two lobes connected by one or more slender threads of chromatin, and cytoplasm containing coarse, round granules that are uniform in size and which can be stained by the dye eosin. Eosinophils are CD9-positive, CD191-positive, and CD193-positive." [GOC:add, GOC:amm, GOC:dsd, GOC:tfm, ISBN:0721601464, PMCID:PMC2626675, PMID:10914487, PMID:1662676] comment: Eosinophils are also CD14-negative, CD32-positive, CD44-positive, CD48-positive, CD69-positive, CD192-negative, MBP1-positive, MBP2-positive, TLR2-negative, TLR4-negative, and lineage-negative (B220, CD2, CD14, CD19, CD56, CD71, CD117, CD123, CD235a (glycophorin A), and TER119). The cytokines IL-3, IL-5, and GM-CSF are involved in their development and differentiation. Usually considered CD16-negative, CD16 is observed on eosinophilic metamyelocyte. subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "eosinocyte" EXACT [] synonym: "eosinophilic granulocyte" EXACT [] @@ -1633,6 +1682,7 @@ id: CL:0000775 name: neutrophil def: "Any of the immature or mature forms of a granular leukocyte that in its mature form has a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes." [GOC:add, GOC:amm, GOC:tfm, ISBN:0721601464] subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "neutrocyte" EXACT [] synonym: "neutrophil leucocyte" EXACT [] @@ -1663,6 +1713,7 @@ id: CL:0000782 name: myeloid dendritic cell def: "A dendritic cell of the myeloid lineage." [GOC:add, PMID:10449155, PMID:17332250, PMID:9521319] comment: These cells are CD1a-negative, CD1b-positive, CD11a-positive, CD11c-positive, CD13-positive, CD14-negative, CD20-negative, CD21-negative, CD33-positive, CD40-negative, CD50-positive, CD54-positive, CD58-positive, CD68-negative, CD80-negative, CD83-negative, CD85j-positive, CD86-positive, CD89-negative, CD95-positive, CD120a-negative, CD120b-positive, CD123-negative, CD178-negative, CD206-negative, CD207-negative, CD209-negative, and TNF-alpha-negative. Upon TLR stimulation, they are capable of producing high levels of TNF-alpha, IL-6, CXCL8 (IL-8). +subset: cellxgene_subset synonym: "CD11c+CD123- DC" EXACT [] synonym: "interdigitating cell" BROAD [] synonym: "mDC" EXACT [] @@ -1681,6 +1732,7 @@ id: CL:0000784 name: plasmacytoid dendritic cell def: "A dendritic cell type of distinct morphology, localization, and surface marker expression (CD123-positive) from other dendritic cell types and associated with early stage immune responses, particularly the release of physiologically abundant amounts of type I interferons in response to infection." [GOC:add, GOC:dsd, PMCID:PMC2118448, PMCID:PMC538703, PMID:15549123, PMID:17332250, PMID:17850486, PMID:20304825] subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "DC2" EXACT [] synonym: "interferon-producing cell" EXACT [] @@ -1703,6 +1755,7 @@ id: CL:0000785 name: mature B cell def: "A B cell that is mature, having left the bone marrow. Initially, these cells are IgM-positive and IgD-positive, and they can be activated by antigen." [GOC:add, GOC:dsd, ISBN:0781735149] comment: Mature B cells are also reportedly CD10-negative, CD19-positive, CD22-positive, CD34-negative, CD48-positive, CD79a-positive, CD84-positive, CD127-negative, CD352-positive, RAG-negative, TdT-negative, Vpre-B-negative, and pre-BCR-negative. Transcription factors expressed: Pax5-positive. +subset: cellxgene_subset synonym: "mature B lymphocyte" EXACT [] synonym: "mature B-cell" EXACT [] synonym: "mature B-lymphocyte" EXACT [] @@ -1725,6 +1778,7 @@ name: plasma cell def: "A terminally differentiated, post-mitotic, antibody secreting cell of the B cell lineage with the phenotype CD138-positive, surface immunonoglobulin-negative, and MHC Class II-negative. Plasma cells are oval or round with extensive rough endoplasmic reticulum, a well-developed Golgi apparatus, and a round nucleus having a characteristic cartwheel heterochromatin pattern and are devoted to producing large amounts of immunoglobulin." [GO_REF:0000031, GOC:add, GOC:dsd, http://en.wikipedia.org/wiki/Plasma_cell, ISBN:0721601464, ISBN:0781735149, PMID:19447676, PMID:20081059, PMID:20839338, PMID:20951740] comment: Plasma cells develop in the spleen and migrate to the bone marrow. Plasma cells are also reportedly CD5-negative, CD10-negative, CD19-positive, CD20-negative, CD21-negative, CD22-negative, CD23-negative, CD24-negative, CD25-negative, CD27-positive, CD34-negative, CD38-positive, CD40-positive, CD43-positive, CD45-positive, CD48-positive, CD53-low, CD80-negative, CD81-positive, CD86-positive, CD95-positive, CD196-negative, CD229-positive, CD270-positive, CD352-positive, CD361-positive, and IgD-negative. Transcription factors: BLIMP1-positive, IRF4-positive, PAX5-negative, SpiB-negative, Ets1-negative, and XBP1-positive. subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "effector B cell" RELATED [] synonym: "effector B-cell" RELATED [] @@ -1757,6 +1811,7 @@ id: CL:0000789 name: alpha-beta T cell def: "A T cell that expresses an alpha-beta T cell receptor complex." [GOC:add, GOC:tfm, ISBN:0781735149] subset: blood_and_immune_upper_slim +subset: cellxgene_subset synonym: "alpha-beta T lymphocyte" EXACT [] synonym: "alpha-beta T-cell" EXACT [] synonym: "alpha-beta T-lymphocyte" EXACT [] @@ -1772,6 +1827,7 @@ name: gamma-delta T cell def: "A T cell that expresses a gamma-delta T cell receptor complex." [GOC:add, GOC:tfm, ISBN:0781735149] comment: Note that gamma-delta T cells have both thymic and extrathymic differentiation pathways. subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "gamma-delta T lymphocyte" EXACT [] synonym: "gamma-delta T-cell" EXACT [] @@ -1790,6 +1846,7 @@ name: immature B cell def: "An immature B cell is a B cell that has the phenotype surface IgM-positive and surface IgD-negative, and have not undergone class immunoglobulin class switching or peripheral encounter with antigen and activation." [GO_REF:0000031, GOC:add, GOC:dsd, GOC:rhs, GOC:tfm, ISBN:0781735149, PMID:20081059, PMID:20839338] comment: Immature B cells are also reportedly CD5-positive, CD10-positive, CD19-positive, CD20-positive, CD21-positive, CD22-positive, CD24-positive, CD25-negative, CD27-negative, CD34-negative, CD38-positive, CD40-positive, CD43-negative, CD45-positive, CD48-positive, CD53-positive, CD79a-positive, CD80-negative, CD81-positive, CD86-negative, CD95-negative, CD127-negative, CD138-negative, CD185-positive, CD196-positive, MHCII/HLA-DR-positive, RAG-positive, TdT-negative, Vpre-B-negative, and preBCR-negative. Transcription factors expressed: Pax5-positive. subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "immature B lymphocyte" EXACT [] synonym: "immature B-cell" EXACT [] @@ -1812,6 +1869,7 @@ relationship: RO:0002104 PR:000001289 ! has plasma membrane part membrane-spanni id: CL:0000817 name: precursor B cell def: "A precursor B cell is a B cell with the phenotype CD10-positive." [GO_REF:0000031, GOC:rhs, GOC:tfm] +subset: cellxgene_subset subset: human_reference_atlas synonym: "pre-B cell" RELATED [] xref: BTO:0001133 @@ -1830,6 +1888,7 @@ id: CL:0000818 name: transitional stage B cell def: "An immature B cell of an intermediate stage between the pre-B cell stage and the mature naive stage with the phenotype surface IgM-positive and CD19-positive, and are subject to the process of B cell selection. A transitional B cell migrates from the bone marrow into the peripheral circulation, and then to the spleen." [GO_REF:0000031, GOC:add, ISBN:0781735149, PMID:12810111, PMID:22343568] comment: This cell type is compatible with the HIPC Lyoplate markers for 'transitional B cell'. +subset: cellxgene_subset subset: human_reference_atlas synonym: "T1 B cell" NARROW [] synonym: "T2 B cell" NARROW [] @@ -1858,6 +1917,7 @@ id: CL:0000826 name: pro-B cell def: "A progenitor cell of the B cell lineage, with some lineage specific activity such as early stages of recombination of B cell receptor genes, but not yet fully committed to the B cell lineage until the expression of PAX5 occurs." [GOC:add, GOC:dsd, ISBN:0781735149, PMID:12633665, PMID:16551251, PMID:18432934] comment: Human pro-B cells are reportedly CD10-positive, CD22-positive, CD34-positive, CD38-positive, CD45-low, CD48-positive, CD79a-positive, CD127-positive, CD184-positive, RAG-positive, TdT-positive, Vpre-B-positive, pre-BCR-negative, IgD-negative, and IgM-negative. Transcription factors expressed: Pax5-positive, EBF-positive, E2A-negative, Ikaros-negative, and PU.1-negative. +subset: cellxgene_subset subset: human_reference_atlas synonym: "pre-B cell (Philadelphia nomenclature)" RELATED [PMID:11244048] synonym: "pre-pro B cell" BROAD [PMID:17582343] @@ -1885,6 +1945,7 @@ relationship: present_in_taxon NCBITaxon:9606 id: CL:0000827 name: pro-T cell def: "A lymphoid progenitor cell of the T cell lineage, with some lineage specific marker expression, but not yet fully committed to the T cell lineage." [GOC:add, ISBN:0781735149] +subset: cellxgene_subset synonym: "DN1 cell" NARROW [] synonym: "DN1 thymocyte" NARROW [] synonym: "pro-T lymphocyte" EXACT [] @@ -1979,6 +2040,7 @@ name: hematopoietic multipotent progenitor cell def: "A hematopoietic multipotent progenitor cell is multipotent, but not capable of long-term self-renewal. These cells are characterized as lacking lineage cell surface markers and being CD34-positive in both mice and humans." [GOC:add, GOC:tfm, PMID:19022770] comment: Markers differ between mouse and human. subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "hemopoietic progenitor cell" EXACT [] synonym: "MPP" EXACT [] @@ -2026,6 +2088,7 @@ id: CL:0000838 name: lymphoid lineage restricted progenitor cell def: "A progenitor cell restricted to the lymphoid lineage." [GOC:add, GOC:tfm] comment: Note that this is a class of cell types, not an identified single cell type. +subset: cellxgene_subset synonym: "lymphoid progenitor cell" BROAD [] xref: BTO:0004731 xref: CALOHA:TS-2025 @@ -2042,6 +2105,7 @@ id: CL:0000839 name: myeloid lineage restricted progenitor cell def: "A progenitor cell restricted to the myeloid lineage." [GOC:add, GOC:tfm, PMID:19022770] comment: Note that this is a class of cell types, not an identified single cell type. +subset: cellxgene_subset subset: human_reference_atlas synonym: "myeloid progenitor cell" BROAD [] xref: BTO:0004730 @@ -2059,6 +2123,7 @@ id: CL:0000842 name: mononuclear cell def: "A leukocyte with a single non-segmented nucleus in the mature form." [GOC:add] subset: blood_and_immune_upper_slim +subset: cellxgene_subset synonym: "mononuclear leukocyte" EXACT [] synonym: "peripheral blood mononuclear cell" NARROW [] xref: BTO:0000878 @@ -2111,6 +2176,7 @@ id: CL:0000954 name: small pre-B-II cell def: "A small pre-B-II cell is a pre-B-II cell that is Rag1-positive, Rag2-positive, pre-BCR-negative, and BCR-negative, is not proliferating, and carries a DNA rearrangement of one or more immunoglobulin light chain genes." [GO_REF:0000031, GOC:dsd, GOC:rhs, GOC:tfm, PMID:16551251, PMID:18432934, PMID:9785673] comment: Small pre-B-II cells are also reportedly CD10-positive, CD19-positive, CD34-negative, CD79a-positive, CD127-negative, TdT-negative, Vpre-B-negative, sIgM-negative, and sIgD-negative. Transcription factors: PU.1-positive, Ikaros-positive, E2A-positive, and PAX5-positive. +subset: cellxgene_subset synonym: "small pre-BII cell" EXACT [] is_a: CL:0000955 {is_inferred="true"} ! pre-B-II cell intersection_of: CL:0000955 ! pre-B-II cell @@ -2148,6 +2214,7 @@ id: CL:0000980 name: plasmablast def: "An activated mature (naive or memory) B cell that is secreting immunoglobulin, typified by being CD27-positive, CD38-positive, CD138-negative." [GO_REF:0000031, GOC:dsd, GOC:msz, GOC:tfm, PMCID:PMC2673126] comment: This cell type is compatible with the HIPC Lyoplate markers for 'plasmablast'. Plasmablasts are also reportedly CD48-positive, CD63-positive, CD229-positive, CD270-positive, CD319-positive, CD352-positive, CD361-positive, and IgD-negative. +subset: cellxgene_subset subset: human_reference_atlas synonym: "CD20-negative B cell" BROAD [] synonym: "CD27-positive, CD38-positive, CD20-negative B cell" EXACT [] @@ -2171,6 +2238,7 @@ relationship: RO:0015015 PR:000001963 ! has high plasma membrane amount CD27 mol id: CL:0000988 name: hematopoietic cell def: "A cell of a hematopoietic lineage." [GO_REF:0000031, GOC:add] +subset: cellxgene_subset synonym: "haematopoietic cell" EXACT [] synonym: "haemopoietic cell" EXACT [] synonym: "hemopoietic cell" EXACT [] @@ -2186,6 +2254,7 @@ name: conventional dendritic cell def: "Conventional dendritic cell is a dendritic cell that is CD11c-high." [GO_REF:0000031, GOC:amm, PMID:17850486] comment: Originally described in the dendritic cell ontology (DC_CL:0000003)(PMID:19243617) These cells are also CD20-negative, MHCII-positive. subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "cDC" EXACT [] synonym: "DC1" EXACT [] @@ -2259,6 +2328,7 @@ id: CL:0001065 name: innate lymphoid cell def: "A lymphocyte that lacks characteristic T cell, B cell, myeloid cell, and dendritic cell markers, that functions as part of the innate immune response to produce cytokines and other effector responses." [GOC:add, GOC:dsd, PMID:23292121, PMID:23348417] subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas is_a: CL:0000542 ! lymphocyte intersection_of: CL:0000542 ! lymphocyte @@ -2310,6 +2380,7 @@ relationship: dc-contributor https://orcid.org/0000-0001-9990-8331 id: CL:0002009 name: macrophage dendritic cell progenitor def: "A progenitor cell that can give rise to plasmacytoid and myeloid dendritic cells, and to monocytes and macrophages." [GOC:tfm, PMID:19273628] +subset: cellxgene_subset synonym: "MDP" EXACT [] is_a: CL:0000763 ! myeloid cell is_a: CL:0002032 {is_inferred="true"} ! hematopoietic oligopotent progenitor cell @@ -2328,6 +2399,7 @@ id: CL:0002028 name: basophil mast progenitor cell def: "A cell type that can give rise to basophil and mast cells. This cell is CD34-positive, CD117-positive, CD125-positive, FceRIa-negative, and T1/ST2-negative, and expresses Gata-1, Gata-2, C/EBPa" [GOC:ak, GOC:dsd, GOC:tfm, PMCID:PMC1312421] comment: There may be an intermediate cell type. These cells also CD13-positive, CD16-positive, CD32-positive, and integrin beta 7-positive. Transcription factors: GATA1-positive, MCP-1-positive, mitf-positive, PU.1-positive, and CEBP/a-low. +subset: cellxgene_subset synonym: "BMCP" EXACT [] is_a: CL:0000763 ! myeloid cell is_a: CL:0002191 ! granulocytopoietic cell @@ -2425,6 +2497,7 @@ id: CL:0002092 name: bone marrow cell def: "A cell found in the bone marrow. This can include fibroblasts, macrophages, adipocytes, osteoblasts, osteoclasts, endothelial cells and hematopoietic cells." [GOC:tfm, ISBN:0618947256] comment: MH consider whether bone marrow cells are bone cells in the structural sense vs. being part of bone organ sense. +subset: cellxgene_subset xref: BTO:0004850 xref: FMA:83621 xref: MESH:D001854 @@ -2440,6 +2513,7 @@ id: CL:0002139 name: endothelial cell of vascular tree def: "An endothelial cell of the vascular tree, which includes blood vessels and lymphatic vessels." [GOC:dsd, GOC:tfm, PMID:12768659] comment: These cells are reportedly CD31-positive, CD34-positive, CD144-positive, TAL1-positive. +subset: cellxgene_subset synonym: "cubodial endothelial cell of vascular tree" NARROW [] synonym: "vascular endothelial cell" EXACT [] xref: BTO:0001854 @@ -2453,6 +2527,7 @@ creation_date: 2010-08-24T02:06:40Z id: CL:0002191 name: granulocytopoietic cell def: "A cell involved in the formation of a granulocyte." [GOC:tfm] +subset: cellxgene_subset xref: FMA:83519 is_a: CL:0000839 {is_inferred="true"} ! myeloid lineage restricted progenitor cell intersection_of: CL:0000839 ! myeloid lineage restricted progenitor cell @@ -2500,6 +2575,7 @@ creation_date: 2010-09-10T03:04:42Z id: CL:0002319 name: neural cell def: "A cell that is part of the nervous system." [GOC:tfm, ISBN:0618947256] +subset: cellxgene_subset xref: CALOHA:TS-2040 xref: FMA:70333 is_a: CL:0000000 ! cell @@ -2513,6 +2589,7 @@ creation_date: 2010-09-15T01:34:57Z id: CL:0002320 name: connective tissue cell def: "A cell of the supporting or framework tissue of the body, arising chiefly from the embryonic mesoderm and including adipose tissue, cartilage, and bone." [GOC:tfm, ISBN:0618947256] +subset: cellxgene_subset xref: CALOHA:TS-2096 xref: FMA:63875 xref: MESH:D003239 @@ -2539,6 +2616,7 @@ id: CL:0002420 name: immature T cell def: "A T cell that has not completed T cell selection." [GOC:tfm] subset: blood_and_immune_upper_slim +subset: cellxgene_subset synonym: "immature T-cell" EXACT [] xref: BTO:0001372 xref: CALOHA:TS-1042 @@ -2629,12 +2707,14 @@ creation_date: 2012-06-27T08:27:35Z id: CL:0008001 name: hematopoietic precursor cell def: "Any hematopoietic cell that is a precursor of some other hematopoietic cell type." [GOC:dos] +subset: cellxgene_subset is_a: CL:0000988 ! hematopoietic cell [Term] id: CL:0008019 name: mesenchymal cell def: "A non-polarised cell precursor cell that is part of some mesenchyme, is associated with the cell matrix but is not connected to other cells and is capable of migration." [] +subset: cellxgene_subset subset: human_reference_atlas synonym: "mesenchyme cell" EXACT [] is_a: CL:0000219 ! motile cell @@ -2654,6 +2734,7 @@ relationship: seeAlso https://github.com/obophenotype/cell-ontology/issues/786 id: CL:0011012 name: neural crest cell def: "A cell of the neural crest. Neural crest cells are multipotent. Premigratory neural crest cells are found at the neural plate boarder, some of which will undergo ectomesynchymal transition and delamination to form migratory neural crest cells." [https://orcid.org/0000-0001-5208-3432, https://orcid.org/0000-0002-9900-7880] +subset: cellxgene_subset is_a: CL:0000048 ! multi fate stem cell is_a: CL:0002321 ! embryonic cell (metazoa) @@ -2661,6 +2742,7 @@ is_a: CL:0002321 ! embryonic cell (metazoa) id: CL:0011026 name: progenitor cell def: "A precursor cell that has a tendency to differentiate into a specific type of cell. They are descendants of stem cells, only they are more constrained in their differentiation potential or capacity for self-renewal, and are often more limited in both senses." [https://doi.org/10.1016/B978-0-12-409503-8.00002-0, ISBN:978-1-62808-994-3] +subset: cellxgene_subset is_a: CL:0011115 ! precursor cell intersection_of: CL:0011115 ! precursor cell intersection_of: develops_from CL:0000034 ! stem cell @@ -2672,6 +2754,7 @@ id: CL:0011115 name: precursor cell def: "A cell that, by division or terminal differentiation, can give rise to other cell types." [GOC:dos] comment: Work is needed on GO 'cell differentiation' before it is clear whether the equivalent class definition 'native cell' that capable_of some 'cell differentiation' works. Also, may want to consider merging this with non-terminally differentiated cell. +subset: cellxgene_subset is_a: CL:0000000 ! cell intersection_of: CL:0000000 ! cell intersection_of: capable_of GO:0030154 ! cell differentiation @@ -2747,17 +2830,6 @@ relationship: bearer_of PATO:0070047 ! polychromatophilic relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2009-12-28T04:25:23Z -[Term] -id: CL:0017505 -name: increased nucleus size -def: "A nucleus size quality which is relatively high compared to the amount of cytoplasm present in the same cell." [GOC:tfm] -is_a: GO:0005634 ! nucleus -intersection_of: GO:0005634 ! nucleus -intersection_of: bearer_of PATO:0000586 ! increased size -relationship: bearer_of PATO:0000586 ! increased size -relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 -creation_date: 2009-12-23T10:53:24Z - [Term] id: CL:0017508 name: cartwheel heterochromatin @@ -2783,6 +2855,7 @@ relationship: part_of UBERON:0012429 ! hematopoietic tissue id: CL:2000001 name: peripheral blood mononuclear cell def: "A leukocyte with a single non-segmented nucleus in the mature form found in the circulatory pool of blood." [GOC:TermGenie] +subset: cellxgene_subset is_a: CL:0000080 ! circulating cell is_a: CL:0000842 ! mononuclear cell intersection_of: CL:0000842 ! mononuclear cell @@ -3866,7 +3939,7 @@ id: GO:0005575 name: cellular_component namespace: cellular_component alt_id: GO:0008372 -def: "A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex)." [GOC:pdt] +def: "A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex)." [GOC:pdt] comment: Note that, in addition to forming the root of the cellular component ontology, this term is recommended for the annotation of gene products whose cellular component is unknown. When this term is used for annotation, it indicates that no information was available about the cellular component of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this. subset: goslim_candida subset: goslim_chembl @@ -3897,8 +3970,8 @@ subset: goslim_metagenomics subset: goslim_mouse subset: goslim_pir subset: goslim_plant +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset synonym: "extracellular" EXACT [] xref: Wikipedia:Extracellular is_a: GO:0110165 ! cellular anatomical entity @@ -3957,7 +4030,7 @@ comment: Note that for multicellular organisms, the extracellular space refers t subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "intercellular space" RELATED [] xref: NIF_Subcellular:sao1425028079 is_a: GO:0110165 ! cellular anatomical entity @@ -4021,8 +4094,8 @@ subset: goslim_flybase_ribbon subset: goslim_generic subset: goslim_metagenomics subset: goslim_pir +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset synonym: "chromatid" RELATED [] synonym: "interphase chromosome" NARROW [] synonym: "prophase chromosome" NARROW [] @@ -4056,8 +4129,8 @@ subset: goslim_chembl subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset xref: Wikipedia:Cytoplasm is_a: GO:0110165 ! cellular anatomical entity relationship: part_of GO:0005622 ! intracellular anatomical structure @@ -4142,8 +4215,8 @@ subset: goslim_generic subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset synonym: "free ribosome" NARROW [NIF_Subcellular:sao1139385046] synonym: "membrane bound ribosome" NARROW [NIF_Subcellular:sao1291545653] synonym: "ribosomal RNA" RELATED [] @@ -4168,8 +4241,8 @@ subset: goslim_generic subset: goslim_metagenomics subset: goslim_mouse subset: goslim_plant +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset synonym: "bacterial inner membrane" NARROW [] synonym: "cell membrane" EXACT [] synonym: "cellular membrane" EXACT [NIF_Subcellular:sao6433132645] @@ -4222,8 +4295,8 @@ def: "Any process in which a new genotype is formed by reassortment of genes res subset: goslim_drosophila subset: goslim_generic subset: goslim_pombe +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset is_a: GO:0006259 ! DNA metabolic process [Term] @@ -4240,7 +4313,7 @@ subset: goslim_drosophila subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "protein anabolism" EXACT [] synonym: "protein biosynthesis" EXACT [] synonym: "protein biosynthetic process" EXACT [] @@ -4312,7 +4385,7 @@ subset: goslim_chembl subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "single-organism transport" RELATED [] is_a: GO:0051234 ! establishment of localization property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20292" xsd:anyURI @@ -4757,9 +4830,9 @@ xref: Wikipedia:Coagulation is_a: GO:0007599 ! hemostasis is_a: GO:0050817 ! coagulation intersection_of: GO:0050817 ! coagulation -intersection_of: has_primary_output UBERON:0010210 ! blood clot -relationship: has_primary_output UBERON:0010210 ! blood clot +intersection_of: results_in_assembly_of UBERON:0010210 ! blood clot relationship: part_of GO:0042060 ! wound healing +relationship: results_in_assembly_of UBERON:0010210 ! blood clot [Term] id: GO:0007599 @@ -4834,7 +4907,7 @@ id: GO:0008219 name: cell death namespace: biological_process def: "Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538)." [GOC:mah, GOC:mtg_apoptosis, PMID:25236395] -comment: This term should not be used for direct annotation, it is currently kept in GO as a placeholder for describing cell death phenotypes in uPHENO. When information is provided on a programmed cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'). Unintentional cell death, i.e. cell death caused by injury, ageing, or cell phenotypes observed as a result of a pathological mutation in an essential gene should NOT be annotated using GO terms. +comment: This term should not be used for direct annotation, it is currently kept in GO as a placeholder for describing cell death phenotypes in uPHENO. When information is provided on a programmed cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'). Unintentional cell death, i.e. cell death caused by injury, ageing, or cell phenotypes observed as a result of a pathological mutation in an essential gene should NOT be annotated using GO terms. subset: gocheck_do_not_annotate synonym: "accidental cell death" RELATED [] synonym: "necrosis" RELATED [] @@ -5038,7 +5111,7 @@ subset: goslim_drosophila subset: goslim_generic subset: goslim_mouse subset: goslim_plant -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "caspase-independent apoptosis" RELATED [] synonym: "caspase-independent cell death" NARROW [] synonym: "non-apoptotic programmed cell death" NARROW [] @@ -5439,8 +5512,8 @@ subset: goslim_flybase_ribbon subset: goslim_generic subset: goslim_mouse subset: goslim_pombe +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset synonym: "biological signaling" EXACT [] synonym: "signaling process" EXACT [] synonym: "signalling" EXACT [] @@ -5467,7 +5540,7 @@ id: GO:0030030 name: cell projection organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon." [GOC:jl, GOC:mah, http://www.cogsci.princeton.edu/~wn/] -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "cell projection organisation" EXACT [] synonym: "cell projection organization and biogenesis" RELATED [GOC:mah] synonym: "cell surface structure organization and biogenesis" RELATED [GOC:mah] @@ -5822,7 +5895,7 @@ subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_pir -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "matrisome" NARROW [] synonym: "proteinaceous extracellular matrix" EXACT [] xref: NIF_Subcellular:nlx_subcell_20090513 @@ -6467,7 +6540,7 @@ subset: goslim_agr subset: goslim_flybase_ribbon subset: goslim_mouse subset: goslim_pir -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "cell process" BROAD [] synonym: "cellular process" BROAD [] synonym: "cellular projection" EXACT [] @@ -6504,12 +6577,14 @@ alt_id: GO:0034960 alt_id: GO:0043283 alt_id: GO:0044259 def: "The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:mah] +subset: gocheck_do_not_annotate subset: goslim_pir synonym: "biopolymer metabolic process" EXACT [GOC:mtg_chebi_dec09] synonym: "macromolecule metabolism" EXACT [] synonym: "multicellular organismal macromolecule metabolic process" NARROW [] synonym: "organismal macromolecule metabolism" EXACT [] is_a: GO:0008152 ! metabolic process +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI [Term] id: GO:0043207 @@ -6527,7 +6602,7 @@ def: "Organized structure of distinctive morphology and function. Includes the n subset: goslim_chembl subset: goslim_generic subset: goslim_pir -subset: prokaryote_subset +subset: goslim_prokaryote xref: NIF_Subcellular:sao1539965131 xref: Wikipedia:Organelle is_a: GO:0110165 ! cellular anatomical entity @@ -6690,9 +6765,11 @@ id: GO:0044238 name: primary metabolic process namespace: biological_process def: "The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism." [GOC:go_curators, http://www.metacyc.org] +subset: gocheck_do_not_annotate subset: goslim_pir synonym: "primary metabolism" EXACT [] is_a: GO:0008152 ! metabolic process +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI [Term] id: GO:0044249 @@ -6745,7 +6822,7 @@ synonym: "innate immunity" EXACT [GOC:pg] synonym: "nonspecific immune response" EXACT [] xref: Wikipedia:Innate_immune_system is_a: GO:0006955 ! immune response -is_a: GO:0098542 ! defense response to other organism +is_a: GO:0140546 ! defense response to symbiont [Term] id: GO:0045190 @@ -7125,6 +7202,7 @@ id: GO:0048856 name: anatomical structure development namespace: biological_process def: "The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome." [GO_REF:0000021] +subset: gocheck_do_not_annotate subset: goslim_chembl subset: goslim_generic subset: goslim_plant @@ -7133,6 +7211,7 @@ is_a: GO:0032502 ! developmental process intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of UBERON:0000061 ! anatomical structure relationship: results_in_development_of UBERON:0000061 ! anatomical structure +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI [Term] id: GO:0048869 @@ -7150,7 +7229,7 @@ def: "Any process involved in the controlled self-propelled movement of a cell t subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "cell locomotion" EXACT [] synonym: "cell movement" RELATED [] synonym: "movement of a cell" EXACT [] @@ -7329,7 +7408,7 @@ subset: goslim_agr subset: goslim_flybase_ribbon subset: goslim_mouse subset: goslim_pir -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "physiological response to stimulus" EXACT [] is_a: GO:0008150 ! biological_process @@ -7541,7 +7620,7 @@ def: "A compound molecular function in which an effector function is controlled subset: gocheck_do_not_manually_annotate subset: goslim_generic subset: goslim_pir -subset: prokaryote_subset +subset: goslim_prokaryote is_a: GO:0003674 ! molecular_function [Term] @@ -7620,7 +7699,7 @@ subset: goslim_drosophila subset: goslim_generic subset: goslim_pir subset: goslim_pombe -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "cellular membrane organisation" EXACT [] synonym: "cellular membrane organization" EXACT [] synonym: "membrane organisation" EXACT [GOC:mah] @@ -7686,7 +7765,7 @@ subset: goslim_generic subset: goslim_metagenomics subset: goslim_pir subset: goslim_pombe -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "cellular macromolecule complex assembly" RELATED [] synonym: "cellular protein complex assembly" EXACT [] synonym: "cellular protein-containing complex assembly" RELATED [] @@ -7794,10 +7873,12 @@ id: GO:0071704 name: organic substance metabolic process namespace: biological_process def: "The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon." [GOC:mah] +subset: gocheck_do_not_annotate synonym: "organic molecular entity metabolic process" EXACT [] synonym: "organic molecular entity metabolism" EXACT [] synonym: "organic substance metabolism" EXACT [] is_a: GO:0008152 ! metabolic process +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI created_by: mah creation_date: 2010-03-08T03:32:18Z @@ -7881,7 +7962,7 @@ creation_date: 2010-09-10T01:39:16Z id: GO:0071944 name: cell periphery namespace: cellular_component -def: "The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures." [GOC:pdt] +def: "The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures." [GOC:pdt] subset: goslim_flybase_ribbon is_a: GO:0110165 ! cellular anatomical entity created_by: mah @@ -8002,7 +8083,7 @@ namespace: biological_process alt_id: GO:0009814 def: "Reactions triggered in response to the presence of another organism that act to protect the cell or organism from damage caused by that organism." [GOC:dos] subset: goslim_generic -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "defence response incompatible interaction" NARROW [] synonym: "defence response to pathogen, incompatible interaction" NARROW [] synonym: "defense response, incompatible interaction" NARROW [] @@ -8217,6 +8298,7 @@ subset: goslim_pir is_a: GO:0005575 ! cellular_component is_a: UBERON:0000061 ! anatomical structure property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24200" xsd:anyURI +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI created_by: kmv creation_date: 2019-08-12T18:01:37Z @@ -8317,6 +8399,16 @@ relationship: has_target_start_location GO:0005622 ! intracellular anatomical st created_by: pg creation_date: 2019-05-22T11:20:45Z +[Term] +id: GO:0140546 +name: defense response to symbiont +namespace: biological_process +def: "Reactions triggered in response to the presence of a symbiont that act to protect or prevent damage to the host." [GOC:pg] +is_a: GO:0098542 ! defense response to other organism +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20261" xsd:anyURI +created_by: pg +creation_date: 2020-11-11T17:19:06Z + [Term] id: GO:1901576 name: organic substance biosynthetic process @@ -8817,30 +8909,6 @@ subset: attribute_slim synonym: "relational shape quality" EXACT [] is_a: PATO:0000051 ! morphology -[Term] -id: PATO:0000068 -name: qualitative -namespace: quality -comment: TODO: define this or obsolete it and move children somewhere else. -is_a: PATO:0000001 ! quality - -[Term] -id: PATO:0000069 -name: deviation (from_normal) -namespace: quality -def: "A quality inhering in a bearer by virtue of the whether the bearer differs from normal or average." [PATOC:GVG] -subset: attribute_slim -is_a: PATO:0000068 ! qualitative - -[Term] -id: PATO:0000117 -name: size -namespace: quality -def: "A morphology quality inhering in a bearer by virtue of the bearer's physical magnitude." [WordNet:WordNet] -subset: attribute_slim -subset: scalar_slim -is_a: PATO:0000051 ! morphology - [Term] id: PATO:0000141 name: structure @@ -8885,36 +8953,6 @@ synonym: "round" RELATED [] synonym: "rounded" RELATED [] is_a: PATO:0000947 ! elliptic -[Term] -id: PATO:0000461 -name: normal -namespace: quality -def: "A quality inhering in a bearer by virtue of the bearer's exhibiting no deviation from normal or average." [PATOC:GVG] -subset: abnormal_slim -subset: mpath_slim -subset: value_slim -synonym: "average" RELATED [] -is_a: PATO:0000068 ! qualitative -property_value: RO:0002604 PATO:0000460 - -[Term] -id: PATO:0000586 -name: increased size -namespace: quality -alt_id: PATO:0001202 -def: "A size quality which is relatively high." [PATOC:GVG] -subset: value_slim -synonym: "big" RELATED [] -synonym: "enlarged" RELATED [] -synonym: "expanded" RELATED [] -synonym: "great" RELATED [] -synonym: "large" RELATED [] -is_a: PATO:0000117 ! size -is_a: PATO:0002305 ! increased object quality -intersection_of: PATO:0000117 ! size -intersection_of: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal -property_value: RO:0002604 PATO:0000587 - [Term] id: PATO:0000947 name: elliptic @@ -9284,32 +9322,6 @@ is_a: PATO:0002078 ! hollow relationship: dc-contributor https://orcid.org/0000-0002-2061-091X creation_date: 2011-06-08T06:33:50Z -[Term] -id: PATO:0002300 -name: increased quality -namespace: quality -def: "A quality that has a value that is increased compared to normal or average." [PATOC:GVG] -is_a: PATO:0000069 ! deviation (from_normal) -intersection_of: PATO:0000001 ! quality -intersection_of: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal -relationship: dc-contributor https://orcid.org/0000-0002-2061-091X -relationship: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal -property_value: RO:0002604 PATO:0002301 -creation_date: 2011-06-16T06:39:43Z - -[Term] -id: PATO:0002305 -name: increased object quality -namespace: quality -def: "A quality of an object that has a value that is increased compared to normal or average." [PATOC:GVG] -is_a: PATO:0001241 ! physical object quality -is_a: PATO:0002300 ! increased quality -intersection_of: PATO:0001241 ! physical object quality -intersection_of: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal -relationship: dc-contributor https://orcid.org/0000-0002-2061-091X -property_value: RO:0002604 PATO:0002303 -creation_date: 2011-06-16T06:54:01Z - [Term] id: PATO:0002318 name: superelliptic @@ -9362,6 +9374,16 @@ comment: A complete coverage of this domain would subclasses homopolymeric, copo subset: value_slim is_a: PATO:0000141 ! structure +[Term] +id: PATO:0040072 +name: high nuclear/cytoplasmic ratio +namespace: quality +def: "A quality inhering in a cell by virtue of the cell having a high nuclear/cytoplasmic ratio." [http://lymerick.net/blood-cells.pdf, Wikipedia:NC_ratio&oldid=931936284] +comment: A high nuclear/cytolasmic ratio is 70% or higher. +synonym: "high N:C ratio" EXACT [] +is_a: PATO:0001396 ! cellular quality +created_by: http://orcid.org/0000-0001-5208-3432 + [Term] id: PATO:0070044 name: anatomical structure quality @@ -10695,7 +10717,7 @@ xref: BILA:0000003 xref: CARO:0000003 xref: EHDAA2:0003003 xref: EMAPA:0 -xref: FBbt:00007001 +xref: FBbt:00007001 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:305751 xref: FMA:67135 xref: GAID:781 @@ -10950,13 +10972,13 @@ synonym: "fertilized egg stage" RELATED [] synonym: "one cell stage" EXACT [] synonym: "one-cell stage" RELATED [VHOG:0000745] synonym: "zygote" RELATED [VHOG:0000745] -synonym: "zygotum" RELATED LATIN [Wikipedia:Zygote] +synonym: "zygotum" RELATED OMO:0003011 [Wikipedia:Zygote] xref: BilaDO:0000005 xref: BILS:0000106 xref: EFO:0001322 xref: EHDAA:27 xref: FBdv:00005288 -xref: IDOMAL:0000302 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: IDOMAL:0000302 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: NCIT:C12601 xref: PdumDv:0000100 xref: VHOG:0000745 @@ -11104,13 +11126,13 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "adult mouth" NARROW [] -synonym: "cavital oralis" RELATED LATIN [Wikipedia:Mouth] +synonym: "cavital oralis" RELATED OMO:0003011 [Wikipedia:Mouth] synonym: "cavitas oris" RELATED [BTO:0001090] synonym: "cavum oris" RELATED [BTO:0001090] synonym: "mouth cavity" RELATED [BTO:0001090] synonym: "oral region" RELATED [EHDAA2:0001326] synonym: "oral vestibule" RELATED [BTO:0001090] -synonym: "regio oralis" EXACT LATIN [BTO:0004698, FMA:49184, FMA:TA] +synonym: "regio oralis" EXACT OMO:0003011 [BTO:0004698, FMA:49184, FMA:TA] synonym: "rima oris" RELATED [BTO:0001090] synonym: "stoma" RELATED [] synonym: "stomatodaeum" RELATED [VHOG:0000812] @@ -11125,7 +11147,7 @@ xref: EFO:0000825 xref: EHDAA2:0001326 xref: EHDAA:542 xref: EMAPA:16262 -xref: FBbt:00003126 +xref: FBbt:00003126 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:49184 xref: GAID:75 xref: galen:Mouth @@ -11308,7 +11330,7 @@ xref: CALOHA:TS-2101 xref: CARO:0000004 xref: EHDAA2:0003004 xref: EMAPA:35178 -xref: FBbt:00007019 +xref: FBbt:00007019 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:9669 xref: galen:BodySubstance xref: HAO:0000004 @@ -11343,7 +11365,7 @@ xref: AEO:0000005 xref: BILA:0000005 xref: CARO:0000005 xref: EHDAA2:0003005 -xref: FBbt:00007017 +xref: FBbt:00007017 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:5897 xref: HAO:0000005 xref: NCIT:C94478 @@ -11371,7 +11393,7 @@ xref: AEO:0000006 xref: BILA:0000006 xref: CARO:0000006 xref: EHDAA2:0003006 -xref: FBbt:00007016 +xref: FBbt:00007016 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:67165 xref: HAO:0000006 xref: TAO:0001836 @@ -11397,7 +11419,7 @@ xref: AEO:0000007 xref: BILA:0000007 xref: CARO:0000007 xref: EHDAA2:0003007 -xref: FBbt:00007015 +xref: FBbt:00007015 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:67112 xref: HAO:0000007 xref: TAO:0001835 @@ -11435,11 +11457,11 @@ xref: EHDAA2:0003011 xref: EHDAA:392 xref: EMAPA:16103 xref: EV:0100000 -xref: FBbt:00004856 +xref: FBbt:00004856 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:7149 xref: galen:AnatomicalSystem xref: HAO:0000011 -xref: IDOMAL:0002460 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: IDOMAL:0002460 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: MA:0000003 xref: NCIT:C12919 xref: SCTID:278195005 @@ -11490,7 +11512,7 @@ xref: EHDAA2:0003191 xref: EHDAA:1 xref: EMAPA:25765 xref: EV:0100016 -xref: FBbt:00000001 +xref: FBbt:00000001 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:256135 xref: galen:Organism xref: HAO:0000012 @@ -11535,7 +11557,7 @@ xref: CARO:0000032 xref: EFO:0000808 xref: EHDAA2:0003032 xref: EMAPA:36031 -xref: FBbt:00007009 +xref: FBbt:00007009 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:7153 xref: galen:BodyPart xref: HAO:0000032 @@ -11571,7 +11593,7 @@ xref: AEO:0000040 xref: BILA:0000040 xref: CARO:0000040 xref: EHDAA2:0003040 -xref: FBbt:00007013 +xref: FBbt:00007013 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:63863 xref: HAO:0000040 xref: TAO:0000382 @@ -11591,8 +11613,7 @@ namespace: uberon def: "Anatomical group whose component anatomical structures lie in close proximity to each other." [FBbt:00007277] subset: common_anatomy subset: upper_level -xref: FBbt:00007277 -xref: IDOMAL:0002461 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: FBbt:00007277 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: VHOG:0001737 is_a: UBERON:0034923 ! disconnected anatomical group relationship: present_in_taxon NCBITaxon:33090 @@ -11619,7 +11640,7 @@ xref: CALOHA:TS-2090 xref: CARO:0000043 xref: EHDAA2:0003043 xref: EMAPA:35868 -xref: FBbt:00007003 +xref: FBbt:00007003 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:9637 xref: galen:Tissue xref: HAO:0000043 @@ -11654,7 +11675,7 @@ xref: AEO:0000055 xref: BILA:0000055 xref: CARO:0000055 xref: EHDAA2:0003055 -xref: FBbt:00007010 +xref: FBbt:00007010 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: HAO:0000055 xref: TAO:0001488 xref: TGMA:0001847 @@ -11687,7 +11708,7 @@ xref: CALOHA:TS-0288 xref: CARO:0000066 xref: EHDAA2:0003066 xref: EMAPA:32738 -xref: FBbt:00007005 +xref: FBbt:00007005 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:9639 xref: GAID:402 xref: HAO:0000066 @@ -11817,11 +11838,11 @@ xref: EHDAA2:0000002 xref: EHDAA2_RETIRED:0003236 xref: EHDAA:38 xref: EMAPA:16039 -xref: FBbt:00000052 +xref: FBbt:00000052 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:69068 xref: GAID:963 xref: http://neurolex.org/wiki/Category\:Embryonic_organism -xref: IDOMAL:0000646 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: IDOMAL:0000646 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: MAT:0000226 xref: MESH:D004622 xref: MIAA:0000019 @@ -11861,7 +11882,7 @@ xref: AAO:0000480 xref: BILA:0000035 xref: BTO:0000556 xref: EMAPA:36033 -xref: FBbt:00000110 +xref: FBbt:00000110 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:69069 xref: GAID:1303 xref: MESH:D005855 @@ -11896,7 +11917,7 @@ xref: EFO:0000414 xref: EHDAA2:0000428 xref: EMAPA:16069 xref: EV:0100003 -xref: FBbt:00000111 +xref: FBbt:00000111 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:69070 xref: GAID:1304 xref: MAT:0000155 @@ -11937,7 +11958,7 @@ xref: EFO:0002545 xref: EHDAA2:0000436 xref: EMAPA:16062 xref: EV:0100005 -xref: FBbt:00000125 +xref: FBbt:00000125 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:69071 xref: GAID:1305 xref: MAT:0000175 @@ -11983,7 +12004,7 @@ xref: EHDAA:160 xref: EHDAA:183 xref: EMAPA:16083 xref: EV:0100006 -xref: FBbt:00000126 +xref: FBbt:00000126 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:69072 xref: GAID:522 xref: MAT:0000174 @@ -12027,7 +12048,7 @@ synonym: "stomodeal-hypophyseal primordium" BROAD [XAO:0000269] xref: BTO:0004224 xref: EHDAA2:0001929 xref: EMAPA:16263 -xref: FBbt:00000439 +xref: FBbt:00000439 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:295846 xref: NCIT:C34306 xref: TAO:0001290 @@ -12174,7 +12195,7 @@ xref: BTO:0000058 xref: CALOHA:TS-1293 xref: EFO:0000793 xref: EV:0100056 -xref: FBbt:00005055 +xref: FBbt:00005055 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:7152 xref: GAID:278 xref: galen:DigestiveSystem @@ -12213,9 +12234,10 @@ namespace: uberon def: "Organ system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis[WP]." [Wikipedia:Circulatory_system] subset: human_reference_atlas subset: uberon_slim -synonym: "systema cardiovasculare" RELATED LATIN [Wikipedia:Circulatory_system] +synonym: "systema cardiovasculare" RELATED OMO:0003011 [Wikipedia:Circulatory_system] xref: AAO:0000959 xref: CALOHA:TS-2103 +xref: MESH:D002319 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} xref: VHOG:0001248 xref: Wikipedia:Circulatory_system is_a: UBERON:0000467 ! anatomical system @@ -12252,7 +12274,7 @@ synonym: "muscles" RELATED [] synonym: "muscles set" EXACT [] synonym: "musculature" EXACT [] synonym: "musculature system" RELATED [] -synonym: "musculi" EXACT LATIN [FMA:32558, FMA:TA] +synonym: "musculi" EXACT OMO:0003011 [FMA:32558, FMA:TA] synonym: "set of muscles" EXACT [FMA:32558] synonym: "set of skeletal muscles" EXACT [MA:0000165] xref: AAO:0011066 @@ -12283,12 +12305,13 @@ namespace: uberon def: "The nervous system is an organ system containing predominantly neuron and glial cells. In bilaterally symmetrical organism, it is arranged in a network of tree-like structures connected to a central body. The main functions of the nervous system are to regulate and control body functions, and to receive sensory input, process this information, and generate behavior [CUMBO]." [BIRNLEX:844, ISBN:0-14-051288-8, ISBN:3110148986, NLM:nervous+system, WB:rynl, Wikipedia:Nervous_system, ZFIN:curator] subset: cumbo subset: efo_slim +subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "nerve net" NARROW [Wikipedia:Nerve_net] synonym: "neurological system" EXACT [GO:0050877] -synonym: "systema nervosum" RELATED LATIN [Wikipedia:Nervous_system] +synonym: "systema nervosum" RELATED OMO:0003011 [Wikipedia:Nervous_system] xref: AAO:0000324 xref: BILA:0000079 xref: BIRNLEX:844 @@ -12299,7 +12322,7 @@ xref: EHDAA2:0001246 xref: EHDAA:826 xref: EMAPA:16469 xref: EV:0100162 -xref: FBbt:00005093 +xref: FBbt:00005093 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:7157 xref: GAID:466 xref: MA:0000016 @@ -12328,6 +12351,7 @@ relationship: has_part CL:0000540 ! neuron relationship: immediate_transformation_of UBERON:0016880 {source="Bgee:AN"} ! future nervous system relationship: never_in_taxon NCBITaxon:6040 relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa +relationship: present_in_taxon NCBITaxon:9606 property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/b/b2/TE-Nervous_system_diagram.svg" xsd:anyURI property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/b/ba/Nervous_system_diagram.png" xsd:anyURI property_value: UBPROP:0000001 "A regulatory system of the body that consists of neurons and neuroglial cells. The nervous system is divided into two parts, the central nervous system (CNS) and the peripheral nervous system (PNS). (Source: BioGlossary, www.Biology-Text.com)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000396", ontology="TAO", source="ZFIN:curator"} @@ -12343,13 +12367,14 @@ namespace: uberon def: "The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the neural tube derivatives: the brain and spinal cord. In invertebrates it includes central ganglia plus nerve cord." [GO:0021551, http://www.frontiersinzoology.com/content/7/1/29, https://sourceforge.net/p/geneontology/ontology-requests/11422/] subset: cumbo subset: efo_slim +subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "cerebrospinal axis" NARROW [FMA:55675] synonym: "CNS" EXACT OMO:0003000 [] synonym: "neuraxis" RELATED [FMA:55675] -synonym: "systema nervosum centrale" EXACT LATIN [FMA:55675, FMA:TA] +synonym: "systema nervosum centrale" EXACT OMO:0003011 [FMA:55675, FMA:TA] xref: AAO:0000090 xref: BAMS:CNS xref: BILA:0000080 @@ -12362,7 +12387,7 @@ xref: EHDAA:828 xref: EMAPA:16470 xref: EMAPA:16754 xref: EV:0100163 -xref: FBbt:00005094 +xref: FBbt:00005094 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:55675 xref: GAID:570 xref: MA:0000167 @@ -12383,6 +12408,7 @@ relationship: immediate_transformation_of UBERON:0016879 {source="Bgee:AN"} ! fu relationship: never_in_taxon NCBITaxon:147099 {source="Wikipedia:Acoelomorpha"} relationship: only_in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of UBERON:0001016 ! nervous system +relationship: present_in_taxon NCBITaxon:9606 property_value: UBPROP:0000001 "Part of the nervous system which includes the brain and spinal cord.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000090", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000001 "The brain and spinal cord. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000012", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "The central nervous system (CNS) is the part of the nervous system which includes the brain, spinal cord, and nerve cell layer of the retina (CUMBO)." xsd:string {source="BIRNLEX:1099"} @@ -12405,7 +12431,7 @@ xref: AEO:0000171 xref: BTO:0001886 xref: EFO:0001652 xref: EHDAA2:0003171 -xref: FBbt:00005495 +xref: FBbt:00005495 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:86589 xref: MAT:0000482 xref: NCIT:C34275 @@ -12425,7 +12451,7 @@ subset: uberon_slim subset: vertebrate_core synonym: "neural primordium" RELATED [] synonym: "presumptive central nervous system" RELATED [] -synonym: "tubus neuralis" RELATED LATIN [Wikipedia:Neural_tube] +synonym: "tubus neuralis" RELATED OMO:0003011 [Wikipedia:Neural_tube] xref: AAO:0010617 xref: BTO:0001057 xref: CALOHA:TS-2371 @@ -12437,7 +12463,7 @@ xref: EMAPA:16164 xref: EMAPA:16757 xref: FMA:293882 xref: MAT:0000069 -xref: MESH:D054259 +xref: MESH:D054259 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: MIAA:0000069 xref: NCIT:C34226 xref: neuronames:1365 @@ -12473,7 +12499,7 @@ xref: BILA:0000000 xref: BIRNLEX:6 xref: CARO:0000000 xref: EHDAA2:0002229 -xref: FBbt:10000000 +xref: FBbt:10000000 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:62955 xref: HAO:0000000 xref: MA:0000001 @@ -12613,10 +12639,11 @@ xref: BTO:0000545 xref: EHDAA2:0000726 xref: EHDAA:518 xref: EMAPA:16247 -xref: FBbt:00003125 +xref: FBbt:00003125 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:45615 xref: galen:AlimentaryTract xref: MA:0000917 +xref: MESH:D041981 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} xref: NCIT:C34082 xref: TAO:0000112 xref: TGMA:0001819 @@ -12718,7 +12745,7 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "region of vascular tree organ" EXACT [FMA:50722] -synonym: "vas sanguineum" RELATED LATIN [Wikipedia:Blood_vessel] +synonym: "vas sanguineum" RELATED OMO:0003011 [Wikipedia:Blood_vessel] synonym: "vascular element" BROAD [EMAPA:35993] synonym: "vascular tree organ region" EXACT [FMA:50722] xref: AAO:0011004 @@ -12833,7 +12860,7 @@ xref: BILA:0000034 xref: BTO:0000174 xref: CALOHA:TS-2110 xref: EFO:0000461 -xref: FBbt:00004208 +xref: FBbt:00004208 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:69067 xref: GAID:407 xref: MESH:D004628 @@ -12909,6 +12936,7 @@ xref: EMAPA:37721 {source="MA:th"} xref: FMA:71221 xref: MA:0002986 xref: MAT:0000148 +xref: MESH:D013131 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} xref: MIAA:0000148 xref: TAO:0000317 xref: VHOG:0000317 @@ -13021,7 +13049,7 @@ namespace: uberon def: "The part of the coelemic cavity lumen that is enclosed by the walls of the thorax." [UBERON:cjm, Wikipedia:Thoracic_cavity] subset: pheno_slim subset: uberon_slim -synonym: "cavitas thoracis" EXACT LATIN [Wikipedia:Thoracic_cavity] +synonym: "cavitas thoracis" EXACT OMO:0003011 [Wikipedia:Thoracic_cavity] synonym: "cavity of chest" EXACT [] synonym: "cavity of thorax" EXACT [] synonym: "chest cavity" EXACT [] @@ -13069,7 +13097,7 @@ synonym: "ventral body cavity" NARROW [NCBITaxon:7742] xref: AEO:0000186 xref: BTO:0001707 xref: EHDAA2:0000267 -xref: FBbt:00005060 +xref: FBbt:00005060 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:85006 xref: galen:BodyCavity xref: NCIT:C25444 @@ -13095,7 +13123,7 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "embryonic notocord" EXACT [] -synonym: "notochorda" RELATED LATIN [Wikipedia:Notochord] +synonym: "notochorda" RELATED OMO:0003011 [Wikipedia:Notochord] synonym: "notocord" EXACT [ZFA:0000135] xref: AAO:0000327 xref: BTO:0001768 @@ -13154,7 +13182,7 @@ synonym: "epithelial somite" RELATED [https://github.com/obophenotype/uberon/wik synonym: "mesodermal cluster" BROAD [GO:0001756] synonym: "somites" RELATED OMO:0003004 [] synonym: "somitic mesoderm" RELATED [] -synonym: "somitus" RELATED LATIN [Wikipedia:Somite] +synonym: "somitus" RELATED OMO:0003011 [Wikipedia:Somite] xref: AAO:0010569 xref: AEO:0001015 xref: BTO:0001558 @@ -13198,7 +13226,7 @@ comment: Gene notes: Many factors and genes, such as Pax3 (Tremblay et al., 1995 subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "crista neuralis" RELATED LATIN [Wikipedia:Neural_crest] +synonym: "crista neuralis" RELATED OMO:0003011 [Wikipedia:Neural_crest] synonym: "NC" EXACT OMO:0003000 [XAO:0000048] synonym: "neural crest material" RELATED [VHOG:0000057] xref: AAO:0010578 @@ -13244,7 +13272,7 @@ namespace: uberon def: "Embryonic ectoderm that gives rise to nervous tissue." [Wikipedia:Neuroectoderm] subset: uberon_slim subset: vertebrate_core -synonym: "epithelium tubi neuralis; neuroectoderma" RELATED LATIN [Wikipedia:Neuroectoderm] +synonym: "epithelium tubi neuralis; neuroectoderma" RELATED OMO:0003011 [Wikipedia:Neuroectoderm] synonym: "neuaral ectoderm" RELATED [] synonym: "neural ectoderm" EXACT [] synonym: "neuroectoderm" EXACT [] @@ -13258,7 +13286,7 @@ xref: EHDAA:1498 xref: EHDAA:255 xref: EMAPA:16073 xref: EV:0100004 -xref: FBbt:00001057 +xref: FBbt:00001057 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:87657 xref: MAT:0000176 xref: MIAA:0000176 @@ -13286,8 +13314,8 @@ subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "medulla of bone" RELATED [BTO:0000141] -synonym: "medulla ossea" EXACT LATIN [BTO:0000141, FMA:9608] -synonym: "medulla ossium" EXACT LATIN [BTO:0000141, Wikipedia:Bone_marrow] +synonym: "medulla ossea" EXACT OMO:0003011 [BTO:0000141, FMA:9608] +synonym: "medulla ossium" EXACT OMO:0003011 [BTO:0000141, Wikipedia:Bone_marrow] synonym: "medullary bone" RELATED [] xref: AAO:0011007 xref: BTO:0000141 @@ -13523,7 +13551,7 @@ subset: vertebrate_core synonym: "blastocyst" RELATED [] synonym: "ectoblast" RELATED [MP:0003886] synonym: "epiblast" EXACT [VHOG:0000243] -synonym: "epiblastus" RELATED LATIN [Wikipedia:Epiblast] +synonym: "epiblastus" RELATED OMO:0003011 [Wikipedia:Epiblast] synonym: "primitive ectoderm" RELATED [VHOG:0000243] xref: BTO:0004593 xref: FMA:296704 @@ -13651,7 +13679,7 @@ def: "A region of embryonic ectodermal cells that lie directly above the notocho subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "lamina neuralis" RELATED LATIN [Wikipedia:Neural_plate] +synonym: "lamina neuralis" RELATED OMO:0003011 [Wikipedia:Neural_plate] synonym: "presumptive central nervous system" RELATED [] xref: AAO:0011072 xref: BTO:0001765 @@ -13661,7 +13689,7 @@ xref: EHDAA:346 xref: EHDAA:902 xref: EMAPA:35593 xref: FMA:293879 -xref: MESH:D054258 +xref: MESH:D054258 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: NCIT:C34225 xref: neuronames:1362 xref: RETIRED_EHDAA2:0001252 @@ -13689,7 +13717,7 @@ def: "The paraxial mesoderm is the mesoderm located bilaterally adjacent to the subset: efo_slim subset: uberon_slim subset: vertebrate_core -synonym: "mesoderma paraxiale" RELATED LATIN [Wikipedia:Paraxial_mesoderm] +synonym: "mesoderma paraxiale" RELATED OMO:0003011 [Wikipedia:Paraxial_mesoderm] synonym: "paraxial mesenchyme" EXACT [https://github.com/obophenotype/uberon/issues/30, https://github.com/obophenotype/uberon/wiki/The-neural-crest, ZFA:0000255] synonym: "somitic mesoderm" EXACT [ISBN:9780878932504] xref: AAO:0010568 @@ -13728,7 +13756,7 @@ synonym: "lateral mesoderm" EXACT [GO:0048368] synonym: "lateral plate" RELATED [] synonym: "lateral plate mesenchyme" RELATED [EHDAA2:0000919] synonym: "LPM" EXACT OMO:0003000 [ZFA:0000121] -synonym: "mesoderma laminae lateralis" RELATED LATIN [Wikipedia:Lateral_plate_mesoderm] +synonym: "mesoderma laminae lateralis" RELATED OMO:0003011 [Wikipedia:Lateral_plate_mesoderm] xref: AAO:0010574 xref: EHDAA2:0000919 xref: EHDAA:379 @@ -13789,10 +13817,10 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "sclerotomes" EXACT OMO:0003004 [TAO:0001080] -synonym: "sclerotomus" RELATED LATIN [Wikipedia:Sclerotome] +synonym: "sclerotomus" RELATED OMO:0003011 [Wikipedia:Sclerotome] xref: AAO:0010571 xref: AEO:0000212 -xref: BTO:0006255 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: BTO:0006255 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: EHDAA2:0003439 xref: EMAPA:31159 xref: FMA:295652 @@ -13843,7 +13871,7 @@ def: "Portion of tissue composed of mesenchymal cells (motile cells that develop subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "mesenchyma" RELATED LATIN [Wikipedia:Mesenchyme] +synonym: "mesenchyma" RELATED OMO:0003011 [Wikipedia:Mesenchyme] synonym: "mesenchymal tissue" EXACT [] synonym: "mesenchyme tissue" EXACT [] synonym: "portion of mesenchymal tissue" EXACT [] @@ -13917,7 +13945,7 @@ def: "Epithelial tubes transport gases, liquids and cells from one site to anoth synonym: "epithelial or endothelial tube" EXACT [] xref: AEO:0000114 xref: EHDAA2:0003114 -xref: FBbt:00007474 +xref: FBbt:00007474 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0000025 ! tube is_a: UBERON:0000483 ! epithelium intersection_of: UBERON:0000483 ! epithelium @@ -14177,6 +14205,7 @@ id: UBERON:0004638 name: blood vessel endothelium namespace: uberon def: "An endothelium that lines the blood vasculature. Other endothelia may line lymph vessels, the heart." [https://orcid.org/0000-0002-6601-2165] +subset: human_reference_atlas subset: pheno_slim subset: vertebrate_core xref: BTO:0000766 @@ -14191,6 +14220,7 @@ is_a: UBERON:0004852 ! cardiovascular system endothelium intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:0001981 ! blood vessel relationship: part_of UBERON:0001981 ! blood vessel +relationship: present_in_taxon NCBITaxon:9606 [Term] id: UBERON:0004716 @@ -14232,7 +14262,7 @@ synonym: "trilaminar disk" RELATED [https://orcid.org/0000-0002-6601-2165] synonym: "trilaminar germ" RELATED [https://orcid.org/0000-0002-6601-2165] xref: BILA:0000060 xref: BTO:0001403 -xref: FBbt:00005317 +xref: FBbt:00005317 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:293108 xref: GAID:1302 xref: MESH:D005775 @@ -14380,7 +14410,7 @@ namespace: uberon def: "Anatomical structure that connects two or more adjacent skeletal elements or hardened body parts." [http://orcid.org/0000-0002-6601-2165] subset: grouping_class synonym: "joint" NARROW [] -xref: FBbt:00005811 +xref: FBbt:00005811 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0034921 ! multi organ part structure relationship: part_of UBERON:0004770 ! articular system @@ -14396,7 +14426,7 @@ synonym: "gut section" RELATED [FBbt:00100315] synonym: "intestinal tract" RELATED [] synonym: "segment of intestinal tract" RELATED [] synonym: "subdivision of alimentary system" RELATED [FMA:71131] -xref: FBbt:00100315 +xref: FBbt:00100315 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:71131 is_a: UBERON:0013522 ! subdivision of tube intersection_of: UBERON:0013522 ! subdivision of tube @@ -14588,7 +14618,7 @@ synonym: "developmental tissue" RELATED [MIAA:0000019] xref: AEO:0000125 xref: CALOHA:TS-2122 xref: EHDAA2:0003125 -xref: FBbt:00007006 +xref: FBbt:00007006 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:292313 xref: MIAA:0000019 is_a: UBERON:0000465 ! material anatomical entity @@ -14605,7 +14635,7 @@ def: "Multi-tissue structure that arises from the heart rudiment and will become subset: vertebrate_core synonym: "early primitive heart tube" NARROW [EMAPA:16208] synonym: "primitive heart tube" EXACT [EMAPA:16215] -xref: BTO:0006179 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: BTO:0006179 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: EHDAA2:0001512 xref: EHDAA:424 xref: EHDAA:436 @@ -14642,7 +14672,7 @@ namespace: uberon def: "An acellular membrane that is part of the epithelium, lies adjacent to the epithelial cells, and is the fusion of the the basal lamina and the reticular lamina." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Basement_membrane] synonym: "basement membrane" RELATED [FMA:63872] synonym: "basement membrane of connective tissue" EXACT [FMA:63872] -synonym: "membrana basalis" EXACT LATIN [Wikipedia:Basement_membrane] +synonym: "membrana basalis" EXACT OMO:0003011 [Wikipedia:Basement_membrane] xref: AAO:0010596 xref: FMA:63872 xref: GAID:915 @@ -14681,7 +14711,7 @@ def: "Subdivision of skeleton which consists of cranial skeleton, set of all ver subset: human_reference_atlas subset: pheno_slim subset: uberon_slim -synonym: "skeleton axiale" RELATED LATIN [Wikipedia:Axial_skeleton] +synonym: "skeleton axiale" RELATED OMO:0003011 [Wikipedia:Axial_skeleton] xref: AAO:0000963 xref: EMAPA:17214 xref: EMAPA:18043 @@ -15105,7 +15135,7 @@ synonym: "organ field" RELATED [] xref: AEO:0000170 xref: EFO:0001649 xref: EHDAA2:0003170 -xref: FBbt:00005426 +xref: FBbt:00005426 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: Wikipedia:Anlage_(biology) is_a: UBERON:0000479 {source="FBbt"} ! tissue is_a: UBERON:0005423 {source="AEO", source="FBbt"} ! developing anatomical structure @@ -15190,7 +15220,7 @@ subset: common_anatomy subset: upper_level synonym: "multicellular structure" EXACT [FBbt:00100313] xref: CARO:0010000 -xref: FBbt:00100313 +xref: FBbt:00100313 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0000061 ! anatomical structure intersection_of: UBERON:0000061 ! anatomical structure intersection_of: has_quality PATO:0001993 ! multicellular @@ -15311,8 +15341,9 @@ name: organ system subdivision namespace: uberon def: "A subdivision of an anatomical system." [http://orcid.org/0000-0002-6601-2165] subset: common_anatomy +subset: human_reference_atlas subset: upper_level -xref: FBbt:00007330 +xref: FBbt:00007330 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:67509 xref: SCTID:91690000 is_a: UBERON:0010000 {source="FBbt"} ! multicellular anatomical structure @@ -15320,6 +15351,7 @@ relationship: part_of UBERON:0000467 ! anatomical system relationship: present_in_taxon NCBITaxon:33090 relationship: present_in_taxon NCBITaxon:33208 ! Metazoa relationship: present_in_taxon NCBITaxon:4751 +relationship: present_in_taxon NCBITaxon:9606 [Term] id: UBERON:0011585 @@ -15451,7 +15483,6 @@ id: UBERON:0013702 name: body proper namespace: uberon def: "The region of the organism associated with the visceral organs." [AEO:0000103] -subset: human_reference_atlas subset: non_informative synonym: "body" RELATED [AEO:0000103] synonym: "whole body" RELATED [BTO:0001489] @@ -15461,7 +15492,6 @@ xref: EMAPA:36031 xref: FMA:231424 is_a: UBERON:0000475 {source="AEO"} ! organism subdivision relationship: part_of UBERON:0013701 ! main body axis -relationship: present_in_taxon NCBITaxon:9606 property_value: UBPROP:0000001 "Cardinal body part, which consists of a maximal set of diverse subclasses of organ and organ part spatially associated with the vertebral column and ribcage. Examples: There is only one body proper[FMA:231424]." xsd:string {source="FMA:231424"} [Term] @@ -15502,7 +15532,7 @@ name: non-connected functional system namespace: uberon def: "An anatomical group whose component structures share a common function." [AEO:0000093, AEO:JB, FBbt:00007278, FBC:DOS] xref: AEO:0000093 -xref: FBbt:00007278 +xref: FBbt:00007278 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0034923 ! disconnected anatomical group [Term] @@ -15628,7 +15658,7 @@ namespace: uberon def: "Material anatomical entity consisting of multiple anatomical structures that are not connected to each other." [CARO:0020000] subset: common_anatomy xref: CARO:0020000 -xref: FBbt:00007276 +xref: FBbt:00007276 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0000465 {source="CARO"} ! material anatomical entity relationship: composed_primarily_of UBERON:0000061 ! anatomical structure relationship: has_component UBERON:0000061 {minCardinality="2"} ! anatomical structure @@ -16052,20 +16082,6 @@ property_value: seeAlso "https://github.com/obophenotype/uberon/wiki/Part-disjoi is_a: RO:0002323 ! mereotopologically related to expand_expression_to: "BFO_0000051 exactly 0 (BFO_0000050 some ?Y)" [] -[Typedef] -id: RO:0002203 -name: develops into -def: "inverse of develops from" [] -subset: RO:0002259 -property_value: IAO:0000114 IAO:0000125 -property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 -property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172 -property_value: IAO:0000117 https://orcid.org/0000-0003-1980-3228 -is_transitive: true -is_a: has_potential_to_develop_into ! has potential to develop into -is_a: RO:0002286 ! developmentally succeeded by -is_a: RO:0002388 ! has potential to directly develop into - [Typedef] id: RO:0002206 name: expressed in @@ -16086,7 +16102,7 @@ def: "inverse of directly develops from" [] subset: RO:0002259 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000118 "developmental precursor of" xsd:string -is_a: RO:0002203 ! develops into +is_a: develops_into ! develops into [Typedef] id: RO:0002222 @@ -16116,7 +16132,7 @@ def: "inverse of has developmental contribution from" [] subset: RO:0002259 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 -holds_over_chain: RO:0002203 part_of +holds_over_chain: develops_into part_of is_a: has_potential_to_developmentally_contribute_to ! has potential to developmentally contribute to is_a: RO:0002286 ! developmentally succeeded by @@ -17401,7 +17417,7 @@ range: BFO:0000004 ! independent continuant is_transitive: true is_a: has_developmental_contribution_from ! has developmental contribution from is_a: RO:0002258 ! developmentally preceded by -inverse_of: RO:0002203 ! develops into +inverse_of: develops_into ! develops into [Typedef] id: develops_from_part_of @@ -17428,6 +17444,22 @@ domain: UBERON:0001062 ! anatomical entity holds_over_chain: directly_develops_from located_in is_a: RO:0002258 ! developmentally preceded by +[Typedef] +id: develops_into +name: develops into +namespace: uberon +def: "inverse of develops from" [] +subset: RO:0002259 +xref: RO:0002203 +property_value: IAO:0000114 IAO:0000125 +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 +property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172 +property_value: IAO:0000117 https://orcid.org/0000-0003-1980-3228 +is_transitive: true +is_a: has_potential_to_develop_into ! has potential to develop into +is_a: RO:0002286 ! developmentally succeeded by +is_a: RO:0002388 ! has potential to directly develop into + [Typedef] id: directly_develops_from name: directly develops from @@ -17762,7 +17794,7 @@ is_a: RO:0002479 ! has part that occurs in id: has_high_plasma_membrane_amount name: obsolete has_high_plasma_membrane_amount def: "OBSOLETE A relation between a cell and molecule or complex such that every instance of the cell has a high number of instances of that molecule expressed on the cell surface. For the formal definition, see Masci et al (PMID:19243617)." [PMID:19243617] -comment: Replaced with RO:0015015, see https://github.com/obophenotype/cell-ontology/issues/1481 +property_value: term_tracker_item https://github.com/obophenotype/cell-ontology/issues/1481 is_obsolete: true replaced_by: RO:0015015 @@ -17789,7 +17821,7 @@ inverse_of: input_of ! input of id: has_low_plasma_membrane_amount name: obsolete has_low_plasma_membrane_amount def: "OBSOLETE A relation between a cell and molecule or complex such that every instance of the cell has a low number of instances of that molecule expressed on the cell surface. For the formal definition, see Masci et al (PMID:19243617)." [PMID:19243617] -comment: Replaced with RO:0015016, see https://github.com/obophenotype/cell-ontology/issues/1481 +property_value: term_tracker_item https://github.com/obophenotype/cell-ontology/issues/1481 is_obsolete: true replaced_by: RO:0015016 @@ -19176,21 +19208,21 @@ is_a: develops_from ! develops from id: transitively_anteriorly_connected_to name: transitively anteriorly connected to namespace: uberon -def: "." [http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern] +property_value: seeAlso "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" xsd:anyURI is_transitive: true [Typedef] id: transitively_distally_connected_to name: transitively distally connected to namespace: uberon -def: "." [http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern] +property_value: seeAlso "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" xsd:anyURI is_transitive: true [Typedef] id: transitively_proximally_connected_to name: transitively proximally connected to namespace: uberon -def: "." [http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern] +property_value: seeAlso "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" xsd:anyURI is_transitive: true [Typedef] diff --git a/src/ontology/subsets/blood_and_immune_upper_slim.owl b/src/ontology/subsets/blood_and_immune_upper_slim.owl index 36e01f07d..d0c2dbd2b 100644 --- a/src/ontology/subsets/blood_and_immune_upper_slim.owl +++ b/src/ontology/subsets/blood_and_immune_upper_slim.owl @@ -18,6 +18,7 @@ xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#" xmlns:skos="http://www.w3.org/2004/02/skos/core#" xmlns:swrl="http://www.w3.org/2003/11/swrl#" + xmlns:sssom="https://w3id.org/sssom/" xmlns:swrla="http://swrl.stanford.edu/ontologies/3.3/swrla.owl#" xmlns:swrlb="http://www.w3.org/2003/11/swrlb#" xmlns:terms="http://purl.org/dc/terms/" @@ -29,8 +30,8 @@ xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#" xmlns:ncbitaxon="http://purl.obolibrary.org/obo/ncbitaxon#"> - - 2024-01-04 + + 2024-02-13 @@ -315,6 +316,14 @@ Annotations: IAO_0000424 "http://purl.obolibrary.org/obo/BFO_0000051 some ( + + + + + + + + @@ -337,6 +346,14 @@ Annotations: IAO_0000424 "http://purl.obolibrary.org/obo/BFO_0000051 some ( + + + + + + + + @@ -846,25 +863,25 @@ WHERE { - + - + - + - + - + - + @@ -1071,14 +1088,6 @@ WHERE { - - - - - - - - @@ -1103,14 +1112,6 @@ WHERE { - - - - - - - - @@ -1942,6 +1943,24 @@ WHERE { + + + + + + + + + + + + + + + + + + - - - - - - - - - - - - - - - - - - - - - A nucleus size quality which is relatively high compared to the amount of cytoplasm present in the same cell. - - 2009-12-23T10:53:24Z - increased nucleus size - - - - - A nucleus size quality which is relatively high compared to the amount of cytoplasm present in the same cell. - GOC:tfm - - - - @@ -16792,6 +16846,7 @@ For example, A and B may be gene products and binding of B by A positively regul 2014-02-11T17:29:04Z CL:2000001 + peripheral blood mononuclear cell @@ -19890,7 +19945,7 @@ For example, A and B may be gene products and binding of B by A positively regul - A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex). + A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex). https://github.com/geneontology/go-ontology/issues/17729 GO:0008372 NIF_Subcellular:sao1337158144 @@ -19911,7 +19966,7 @@ For example, A and B may be gene products and binding of B by A positively regul - A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex). + A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex). GOC:pdt @@ -19941,8 +19996,8 @@ For example, A and B may be gene products and binding of B by A positively regul + - Note that this term is intended to annotate gene products that are not attached to the cell surface. For gene products from multicellular organisms which are secreted from a cell but retained within the organism (i.e. released into the interstitial fluid or blood), consider the cellular component term 'extracellular space ; GO:0005615'. extracellular region @@ -19987,32 +20042,32 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + A protein complex consisting of three collagen chains assembled into a left-handed triple helix. These trimers typically assemble into higher order structures. Wikipedia:Collagen cellular_component GO:0005581 collagen trimer - + - + - + PMID:12382326 - + PMID:12382326 @@ -20094,7 +20149,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Note that for multicellular organisms, the extracellular space refers to everything outside a cell, but still within the organism (excluding the extracellular matrix). Gene products from a multi-cellular organism that are secreted from a cell into the interstitial fluid or blood can therefore be annotated to this term. extracellular space @@ -20234,8 +20289,8 @@ For example, A and B may be gene products and binding of B by A positively regul + - Chromosomes include parts that are not part of the chromatin. Examples include the kinetochore. chromosome @@ -20301,8 +20356,8 @@ For example, A and B may be gene products and binding of B by A positively regul + - cytoplasm @@ -20479,8 +20534,8 @@ For example, A and B may be gene products and binding of B by A positively regul + - ribosome @@ -20539,8 +20594,8 @@ For example, A and B may be gene products and binding of B by A positively regul + - plasma membrane @@ -20637,8 +20692,8 @@ For example, A and B may be gene products and binding of B by A positively regul + - DNA recombination @@ -20698,7 +20753,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + translation @@ -20826,7 +20881,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Note that this term should not be used for direct annotation. It should be possible to make a more specific annotation to one of the children of this term, for e.g. to transmembrane transport, to microtubule-based transport or to vesicle-mediated transport. transport @@ -21954,7 +22009,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -21970,7 +22025,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -22115,7 +22170,7 @@ For example, A and B may be gene products and binding of B by A positively regul necrosis GO:0008219 - This term should not be used for direct annotation, it is currently kept in GO as a placeholder for describing cell death phenotypes in uPHENO. When information is provided on a programmed cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'). Unintentional cell death, i.e. cell death caused by injury, ageing, or cell phenotypes observed as a result of a pathological mutation in an essential gene should NOT be annotated using GO terms. + This term should not be used for direct annotation, it is currently kept in GO as a placeholder for describing cell death phenotypes in uPHENO. When information is provided on a programmed cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'). Unintentional cell death, i.e. cell death caused by injury, ageing, or cell phenotypes observed as a result of a pathological mutation in an essential gene should NOT be annotated using GO terms. cell death @@ -22569,7 +22624,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Note that this term should be used to annotate gene products in the organism undergoing the programmed cell death. To annotate genes in another organism whose products modulate programmed cell death in a host organism, consider the term 'modulation by symbiont of host programmed cell death ; GO:0052040'. Also, note that 'programmed cell death ; GO:0012501' should be used to refer to instances of caspase-independent cell death mechanisms, in the absence of further indications on the process taking place. At present, caspase-independent cell death is not yet represented in GO due to the lack of consensus and in-depth research on the topic. 'programmed cell death ; GO:0012501' may also be used to annotate gene products in taxa where apoptosis as defined in GO:0006915 does not occur, such as plants. You may also consider these specific children: GO:0097468 'programmed cell death in response to reactive oxygen species' (with descendants GO:0010421 'hydrogen peroxide-mediated programmed cell death' and GO:0010343 'singlet oxygen-mediated programmed cell death'), and GO:0009626 'plant-type hypersensitive response' and its children. programmed cell death @@ -23617,8 +23672,8 @@ For example, A and B may be gene products and binding of B by A positively regul + - Note that a signal is any variable property or parameter that serves to convey information, and may be a physical entity such as a gene product or small molecule, a photon, or a change in state such as movement or voltage change. signaling @@ -23710,7 +23765,7 @@ For example, A and B may be gene products and binding of B by A positively regul cell projection organization and biogenesis cell surface structure organization and biogenesis GO:0030030 - + cell projection organization @@ -24731,7 +24786,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + extracellular matrix @@ -26450,7 +26505,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + cell projection @@ -26537,6 +26592,7 @@ For example, A and B may be gene products and binding of B by A positively regul The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. + https://github.com/geneontology/go-ontology/issues/26424 GO:0034960 GO:0043283 GO:0044259 @@ -26546,6 +26602,7 @@ For example, A and B may be gene products and binding of B by A positively regul multicellular organismal macromolecule metabolic process biological_process GO:0043170 + macromolecule metabolic process @@ -26595,7 +26652,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + organelle @@ -27019,9 +27076,11 @@ For example, A and B may be gene products and binding of B by A positively regul The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism. + https://github.com/geneontology/go-ontology/issues/26424 primary metabolism biological_process GO:0044238 + primary metabolic process @@ -27124,7 +27183,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. GO:0002226 Wikipedia:Innate_immune_system @@ -28268,9 +28327,11 @@ For example, A and B may be gene products and binding of B by A positively regul The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. + https://github.com/geneontology/go-ontology/issues/26424 development of an anatomical structure biological_process GO:0048856 + @@ -28318,7 +28379,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + cell motility @@ -28796,7 +28857,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. response to stimulus @@ -29336,7 +29397,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + molecular transducer activity @@ -29601,7 +29662,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + membrane organization @@ -29768,7 +29829,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + protein-containing complex assembly @@ -30048,6 +30109,7 @@ For example, A and B may be gene products and binding of B by A positively regul The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon. + https://github.com/geneontology/go-ontology/issues/26424 mah 2010-03-08T03:32:18Z organic molecular entity metabolic process @@ -30055,6 +30117,7 @@ For example, A and B may be gene products and binding of B by A positively regul organic substance metabolism biological_process GO:0071704 + organic substance metabolic process @@ -30298,7 +30361,7 @@ For example, A and B may be gene products and binding of B by A positively regul - The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures. + The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures. mah 2010-10-04T01:51:47Z cellular_component @@ -30309,7 +30372,7 @@ For example, A and B may be gene products and binding of B by A positively regul - The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures. + The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures. GOC:pdt @@ -30639,7 +30702,7 @@ For example, A and B may be gene products and binding of B by A positively regul biological_process GO:0098542 - + defense response to other organism @@ -31284,6 +31347,7 @@ For example, A and B may be gene products and binding of B by A positively regul A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex but below that of an anatomical system. Or, a substance produced by a cellular organism with granularity above the level of a protein complex. https://github.com/geneontology/go-ontology/issues/24200 + https://github.com/geneontology/go-ontology/issues/26424 kmv 2019-08-12T18:01:37Z cellular_component @@ -31571,6 +31635,27 @@ For example, A and B may be gene products and binding of B by A positively regul + + + + + Reactions triggered in response to the presence of a symbiont that act to protect or prevent damage to the host. + https://github.com/geneontology/go-ontology/issues/20261 + pg + 2020-11-11T17:19:06Z + biological_process + GO:0140546 + defense response to symbiont + + + + + Reactions triggered in response to the presence of a symbiont that act to protect or prevent damage to the host. + GOC:pg + + + + @@ -32880,57 +32965,6 @@ For example, A and B may be gene products and binding of B by A positively regul - - - - - quality - PATO:0000068 - TODO: define this or obsolete it and move children somewhere else. - qualitative - - - - - - - - - A quality inhering in a bearer by virtue of the whether the bearer differs from normal or average. - quality - PATO:0000069 - - deviation (from_normal) - - - - - A quality inhering in a bearer by virtue of the whether the bearer differs from normal or average. - PATOC:GVG - - - - - - - - - A morphology quality inhering in a bearer by virtue of the bearer's physical magnitude. - quality - PATO:0000117 - - - size - - - - - A morphology quality inhering in a bearer by virtue of the bearer's physical magnitude. - WordNet:WordNet - - - - @@ -33025,67 +33059,6 @@ For example, A and B may be gene products and binding of B by A positively regul - - - - - A quality inhering in a bearer by virtue of the bearer's exhibiting no deviation from normal or average. - - quality - average - PATO:0000461 - - - - normal - - - - - A quality inhering in a bearer by virtue of the bearer's exhibiting no deviation from normal or average. - PATOC:GVG - - - - - - - - - - - - - - - - - - - - - A size quality which is relatively high. - - PATO:0001202 - quality - big - enlarged - expanded - great - large - PATO:0000586 - - increased size - - - - - A size quality which is relatively high. - PATOC:GVG - - - - @@ -33861,77 +33834,6 @@ For example, A and B may be gene products and binding of B by A positively regul - - - - - - - - - - - - - - - - - - - - - - A quality that has a value that is increased compared to normal or average. - - - 2011-06-16T06:39:43Z - quality - PATO:0002300 - increased quality - - - - - A quality that has a value that is increased compared to normal or average. - PATOC:GVG - - - - - - - - - - - - - - - - - - - - - A quality of an object that has a value that is increased compared to normal or average. - - - 2011-06-16T06:54:01Z - quality - PATO:0002305 - increased object quality - - - - - A quality of an object that has a value that is increased compared to normal or average. - PATOC:GVG - - - - @@ -34040,6 +33942,28 @@ For example, A and B may be gene products and binding of B by A positively regul + + + + + A quality inhering in a cell by virtue of the cell having a high nuclear/cytoplasmic ratio. + http://orcid.org/0000-0001-5208-3432 + high N:C ratio + quality + PATO:0040072 + A high nuclear/cytolasmic ratio is 70% or higher. + high nuclear/cytoplasmic ratio + + + + + A quality inhering in a cell by virtue of the cell having a high nuclear/cytoplasmic ratio. + Wikipedia:NC_ratio&oldid=931936284 + http://lymerick.net/blood-cells.pdf + + + + @@ -37533,6 +37457,12 @@ For example, A and B may be gene products and binding of B by A positively regul Material anatomical entity that is a single connected structure with inherent 3D shape generated by coordinated expression of the organism's own genome. CARO:0000003 + + + + FBbt:00007001 + + @@ -38084,7 +38014,9 @@ For example, A and B may be gene products and binding of B by A positively regul IDOMAL:0000302 - https://orcid.org/0000-0003-4423-4370 + + + https://github.com/biopragmatics/biomappings @@ -38109,7 +38041,7 @@ For example, A and B may be gene products and binding of B by A positively regul zygotum Wikipedia:Zygote - + @@ -38233,7 +38165,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -38269,14 +38201,14 @@ For example, A and B may be gene products and binding of B by A positively regul gastrula stage - + - + BILS @@ -38554,6 +38486,12 @@ For example, A and B may be gene products and binding of B by A positively regul in FMA, the tongue, palate etc are part of the mouth which is itself a subdivision of the face. ZFA includes a separate class 'oral region' which is part of the mouth, but excludes tongue and lips FMA + + + + FBbt:00003126 + + @@ -38561,14 +38499,14 @@ For example, A and B may be gene products and binding of B by A positively regul BTO:0004698 FMA:49184 FMA:TA - + cavital oralis Wikipedia:Mouth - + @@ -38644,15 +38582,15 @@ For example, A and B may be gene products and binding of B by A positively regul - + - - + + A fluid that is composed of blood plasma and erythrocytes. This class excludes blood analogues, such as the insect analog of blood. See UBERON:0000179 haemolymphatic fluid. @@ -38694,34 +38632,34 @@ For example, A and B may be gene products and binding of B by A positively regul blood - + - + - + - + CL:tm - + https://github.com/obophenotype/uberon/issues/1330 - + Bgee:AN @@ -39025,7 +38963,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -39067,14 +39005,14 @@ For example, A and B may be gene products and binding of B by A positively regul organism substance - + - + this relationship may be too strong and may be weakened in future @@ -39083,6 +39021,12 @@ For example, A and B may be gene products and binding of B by A positively regul Material anatomical entity in a gaseous, liquid, semisolid or solid state; produced by anatomical structures or derived from inhaled and ingested substances that have been modified by anatomical structures as they pass through the body. http://orcid.org/0000-0001-9114-8737 + + + + FBbt:00007019 + + @@ -39161,6 +39105,12 @@ For example, A and B may be gene products and binding of B by A positively regul Non-material anatomical entity of three dimensions, that is generated by morphogenetic or other physiologic processes; is surrounded by one or more anatomical structures; contains one or more organism substances or anatomical structures. http://orcid.org/0000-0001-9114-8737 + + + + FBbt:00007017 + + @@ -39210,6 +39160,12 @@ For example, A and B may be gene products and binding of B by A positively regul Anatomical entity that has mass. http://orcid.org/0000-0001-9114-8737 + + + + FBbt:00007016 + + @@ -39246,6 +39202,12 @@ For example, A and B may be gene products and binding of B by A positively regul Anatomical entity that has no mass. http://orcid.org/0000-0001-9114-8737 + + + + FBbt:00007015 + + @@ -39331,11 +39293,19 @@ For example, A and B may be gene products and binding of B by A positively regul system GO:0048731 + + + + FBbt:00004856 + + IDOMAL:0002460 - https://orcid.org/0000-0003-4423-4370 + + + https://github.com/biopragmatics/biomappings @@ -39434,6 +39404,12 @@ For example, A and B may be gene products and binding of B by A positively regul VHOG:0000671 WBbt:0007833 + + + + FBbt:00000001 + + @@ -39537,6 +39513,12 @@ For example, A and B may be gene products and binding of B by A positively regul CARO:DOS http://orcid.org/0000-0001-9114-8737 + + + + FBbt:00007009 + + @@ -39604,6 +39586,12 @@ For example, A and B may be gene products and binding of B by A positively regul Anatomical structure that consists of cell parts and cell substances and together does not constitute a cell or a tissue. http://orcid.org/0000-0001-9114-8737 + + + + FBbt:00007013 + + @@ -39623,7 +39611,6 @@ For example, A and B may be gene products and binding of B by A positively regul FBbt:00007277 - IDOMAL:0002461 VHOG:0001737 uberon UBERON:0000477 @@ -39640,8 +39627,8 @@ For example, A and B may be gene products and binding of B by A positively regul - IDOMAL:0002461 - https://orcid.org/0000-0003-4423-4370 + FBbt:00007277 + @@ -39712,6 +39699,12 @@ For example, A and B may be gene products and binding of B by A positively regul Multicellular anatomical structure that consists of many cells of one or a few types, arranged in an extracellular matrix such that their long-range organisation is at least partly a repetition of their short-range organisation. CARO:0000043 + + + + FBbt:00007003 + + @@ -39779,6 +39772,12 @@ For example, A and B may be gene products and binding of B by A positively regul CARO:0000055 http://orcid.org/0000-0001-9114-8737 + + + + FBbt:00007010 + + @@ -39817,7 +39816,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -39861,14 +39860,14 @@ For example, A and B may be gene products and binding of B by A positively regul epithelium https://upload.wikimedia.org/wikipedia/commons/8/8f/Illu_epithelium.jpg - + - + http://palaeos.com/metazoa/porifera/homoscleromorpha.html @@ -39888,6 +39887,12 @@ For example, A and B may be gene products and binding of B by A positively regul ISBN:978-0030259821 Ruppert EE, Fox RS, Barnes RD, Invertebrate zoology: a functional evolutionary approach (2003) p.59 http://bgee.unil.ch/ + + + + FBbt:00007005 + + @@ -40203,11 +40208,19 @@ For example, A and B may be gene products and binding of B by A positively regul Obsoleted in ZFA. Note that embryo is not classified as an embryonic structure - an embryonic structure is only the parts of an embryo ZFA + + + + FBbt:00000052 + + IDOMAL:0000646 - https://orcid.org/0000-0003-4423-4370 + + + https://github.com/biopragmatics/biomappings @@ -40294,6 +40307,12 @@ For example, A and B may be gene products and binding of B by A positively regul embryonic tissue FMA:69069 + + + + FBbt:00000110 + + @@ -40332,7 +40351,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Primary germ layer that is the outer of the embryo's three germ layers and gives rise to epidermis and neural tissue. Primary germ layer that is the outer of the embryonic germ layers and gives rise to epidermis and neural tissue.[AAO] The Bilateria are triploblastic (with true endoderm, mesoderm, and ectoderm) (...).[well established][VHOG] @@ -40370,14 +40389,14 @@ For example, A and B may be gene products and binding of B by A positively regul ectoderm http://upload.wikimedia.org/wikipedia/commons/1/19/Gray32.png - + - + Bgee:AN @@ -40405,6 +40424,12 @@ For example, A and B may be gene products and binding of B by A positively regul ISBN:978-0878932504 Gilbert SF, Developmental Biology (2006) Limb development and evolution, p.722 http://bgee.unil.ch/ + + + + FBbt:00000111 + + @@ -40430,7 +40455,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Primary germ layer that lies remote from the surface of the embryo and gives rise to internal tissues such as gut. The Bilateria are triploblastic (with true endoderm, mesoderm, and ectoderm) (...).[well established][VHOG] endodermal @@ -40467,14 +40492,14 @@ For example, A and B may be gene products and binding of B by A positively regul http://upload.wikimedia.org/wikipedia/commons/c/c0/Endoderm2.png http://upload.wikimedia.org/wikipedia/commons/d/df/Gray10.png - + - + Bgee:AN @@ -40493,6 +40518,12 @@ For example, A and B may be gene products and binding of B by A positively regul ISBN:978-0878932504 Gilbert SF, Developmental Biology (2006) Limb development and evolution, p.722 http://bgee.unil.ch/ + + + + FBbt:00000125 + + @@ -40519,7 +40550,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + The middle germ layer of the embryo, between the endoderm and ectoderm. Primary germ layer that is the middle of the embryonic germ layers.[AAO] @@ -40564,7 +40595,7 @@ For example, A and B may be gene products and binding of B by A positively regul mesoderm http://upload.wikimedia.org/wikipedia/commons/e/e8/Mesoderm.png - + @@ -40577,7 +40608,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Bgee:AN @@ -40611,6 +40642,12 @@ For example, A and B may be gene products and binding of B by A positively regul sponges do not seem to have a mesoderm and accordingly Amphimedon lacks transcription factors involved in mesoderm development (Fkh, Gsc, Twist, Snail)[http://www.nature.com/nature/journal/v466/n7307/full/nature09201.html]. Mesoderm may not be homologous across verteberates https://github.com/obophenotype/uberon/wiki/The-neural-crest + + + + FBbt:00000126 + + @@ -40720,6 +40757,12 @@ For example, A and B may be gene products and binding of B by A positively regul stomodeal-hypophyseal primordium XAO:0000269 + + + + FBbt:00000439 + + @@ -40784,7 +40827,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -40861,14 +40904,14 @@ For example, A and B may be gene products and binding of B by A positively regul https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Heart.glb https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Heart.glb - + - + MA @@ -41154,6 +41197,12 @@ For example, A and B may be gene products and binding of B by A positively regul many anatomy ontologies consider gastrointestinal system synonymous with digestive system. here we follow MA in dividing digestive system into gastrointestinal and hepatobiliary. hepatobiliary includes the liver and biliary tract. species-specific AO classes are categorized according to whether liver is included. For example, XAO includes liver as part of XAO:0000125 alimentary system, so we assume this class is the more generic class MA + + + + FBbt:00005055 + + @@ -41195,6 +41244,7 @@ For example, A and B may be gene products and binding of B by A positively regul We should divest ourselves of the view that earlier vertebrate groups were 'on their way' to becoming mammals, as clearly they were not such visionaries. Neither were their systems 'imperfect' as earlier anatomists thought. Instead, their circulatory systems served them well to address the ecological demands arising from their lifestyles.[well established][VHOG] AAO:0000959 CALOHA:TS-2103 + MESH:D002319 VHOG:0001248 Wikipedia:Circulatory_system uberon @@ -41242,12 +41292,19 @@ For example, A and B may be gene products and binding of B by A positively regul ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.493 http://bgee.unil.ch/ + + + + MESH:D002319 + + https://github.com/biopragmatics/biomappings + systema cardiovasculare Wikipedia:Circulatory_system - + @@ -41328,7 +41385,7 @@ For example, A and B may be gene products and binding of B by A positively regul musculi FMA:32558 FMA:TA - + @@ -41379,13 +41436,14 @@ For example, A and B may be gene products and binding of B by A positively regul - + The nervous system is an organ system containing predominantly neuron and glial cells. In bilaterally symmetrical organism, it is arranged in a network of tree-like structures connected to a central body. The main functions of the nervous system are to regulate and control body functions, and to receive sensory input, process this information, and generate behavior [CUMBO]. + A regulatory system of the body that consists of neurons and neuroglial cells. The nervous system is divided into two parts, the central nervous system (CNS) and the peripheral nervous system (PNS). (Source: BioGlossary, www.Biology-Text.com)[TAO] Anatomical system consisting of nerve bodies and nerve fibers which regulate the response of the body to external and internal stimuli.[AAO] Nervous systems evolved in the ancestor of Eumetazoa.[well established][VHOG] @@ -41425,6 +41483,7 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0001016 + @@ -41432,14 +41491,14 @@ For example, A and B may be gene products and binding of B by A positively regul http://upload.wikimedia.org/wikipedia/commons/b/b2/TE-Nervous_system_diagram.svg http://upload.wikimedia.org/wikipedia/commons/b/ba/Nervous_system_diagram.png - + - + Bgee:AN @@ -41482,6 +41541,12 @@ For example, A and B may be gene products and binding of B by A positively regul ISBN:978-0198566694 Schmidt-Rhaesa A, The evolution of organ systems (2007) p.117 http://bgee.unil.ch/ + + + + FBbt:00005093 + + @@ -41505,7 +41570,7 @@ For example, A and B may be gene products and binding of B by A positively regul systema nervosum Wikipedia:Nervous_system - + @@ -41527,9 +41592,10 @@ For example, A and B may be gene products and binding of B by A positively regul - + The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the neural tube derivatives: the brain and spinal cord. In invertebrates it includes central ganglia plus nerve cord. + Part of the nervous system which includes the brain and spinal cord.[AAO] The brain and spinal cord. Kimmel et al, 1995.[TAO] The central nervous system (CNS) is the part of the nervous system which includes the brain, spinal cord, and nerve cell layer of the retina (CUMBO). @@ -41569,12 +41635,13 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0001017 + central nervous system - + @@ -41588,7 +41655,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Bgee:AN @@ -41639,6 +41706,12 @@ For example, A and B may be gene products and binding of B by A positively regul ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.28 (reference 1), ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.165 (reference 2), DOI:10.1016/j.cell.2007.02.040 Denes AS, Jekely G, Steinmetz PRH, Raible F, Snyman H, Prud'homme B, Ferrier DEK, Balavoine G and Arendt D, Molecular architecture of annelid nerve cord supports common origin of nervous system centralization in Bilateria. Cell (2007) (reference 3) http://bgee.unil.ch/ + + + + FBbt:00005094 + + @@ -41658,7 +41731,7 @@ For example, A and B may be gene products and binding of B by A positively regul systema nervosum centrale FMA:55675 FMA:TA - + @@ -41724,6 +41797,12 @@ For example, A and B may be gene products and binding of B by A positively regul FB:FBrf0089570 http://flybase.org/reports/FBrf0178740.html + + + + FBbt:00005495 + + @@ -41844,6 +41923,14 @@ For example, A and B may be gene products and binding of B by A positively regul The mature structure of the neural tube exists when the tube has been segmented into the forebrain, midbrain, hindbrain and spinal cord regions. In addition neural crest has budded away from the epithelium GO:0021915 + + + + MESH:D054259 + + + https://github.com/biopragmatics/biomappings + @@ -41855,7 +41942,7 @@ For example, A and B may be gene products and binding of B by A positively regul tubus neuralis Wikipedia:Neural_tube - + @@ -41898,6 +41985,12 @@ For example, A and B may be gene products and binding of B by A positively regul FMA:62955 http://orcid.org/0000-0001-9114-8737 + + + + FBbt:10000000 + + @@ -42272,6 +42365,7 @@ For example, A and B may be gene products and binding of B by A positively regul FBbt:00003125 FMA:45615 MA:0000917 + MESH:D041981 NCIT:C34082 TAO:0000112 TGMA:0001819 @@ -42353,6 +42447,19 @@ For example, A and B may be gene products and binding of B by A positively regul we place the MA and EMAPA class here, although the intent is probably a smaller region. See https://github.com/obophenotype/uberon/issues/509 MA + + + + FBbt:00003125 + + + + + + MESH:D041981 + + https://github.com/biopragmatics/biomappings + @@ -42577,8 +42684,8 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -42591,7 +42698,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -42650,34 +42757,34 @@ For example, A and B may be gene products and binding of B by A positively regul blood vessel http://upload.wikimedia.org/wikipedia/commons/2/29/Circulatory_System_en.svg - + - + - + - + AEO - + EHDAA2 - + GO:0072360 @@ -42750,7 +42857,7 @@ For example, A and B may be gene products and binding of B by A positively regul vas sanguineum Wikipedia:Blood_vessel - + @@ -42984,6 +43091,12 @@ For example, A and B may be gene products and binding of B by A positively regul in FMA embryo is_a embryonic structure FMA + + + + FBbt:00004208 + + @@ -43161,6 +43274,7 @@ For example, A and B may be gene products and binding of B by A positively regul FMA:71221 MA:0002986 MAT:0000148 + MESH:D013131 MIAA:0000148 TAO:0000317 VHOG:0000317 @@ -43236,6 +43350,13 @@ For example, A and B may be gene products and binding of B by A positively regul EMAPA:37721 MA:th + + + + MESH:D013131 + + https://github.com/biopragmatics/biomappings + @@ -43400,7 +43521,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -43434,14 +43555,14 @@ For example, A and B may be gene products and binding of B by A positively regul musculoskeletal system - + - + check ctenophore @@ -43555,7 +43676,7 @@ For example, A and B may be gene products and binding of B by A positively regul cavitas thoracis Wikipedia:Thoracic_cavity - + @@ -43570,7 +43691,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -43611,14 +43732,14 @@ For example, A and B may be gene products and binding of B by A positively regul EDITOR_NOTE check the FMA placement here; ncit placement of body cavity here probably not correct coelemic cavity lumen - + - + definitional @@ -43651,6 +43772,12 @@ For example, A and B may be gene products and binding of B by A positively regul body cavity BTO:0001707 + + + + FBbt:00005060 + + @@ -43726,9 +43853,9 @@ For example, A and B may be gene products and binding of B by A positively regul - - - + + + @@ -43783,15 +43910,15 @@ For example, A and B may be gene products and binding of B by A positively regul notochord http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + - + - + @@ -43810,19 +43937,19 @@ For example, A and B may be gene products and binding of B by A positively regul - + http://tolweb.org/Chordata/2499 - + ZFA - + EHDAA2 @@ -43897,7 +44024,7 @@ For example, A and B may be gene products and binding of B by A positively regul notochorda Wikipedia:Notochord - + @@ -43907,8 +44034,8 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + Somites are spheres of epithelial cells that form sequentially along the anterior-posterior axis of the embryo through mesenchymal to epithelial transition of the presomitic mesoderm. EDITOR_NOTE currently classified as an epithelial vesicle, consistent with EHDAA2 and https://github.com/obophenotype/uberon/wiki/The-neural-crest. Consider making 'somitic mesoderm' a separate term and correlate with regionalization processes. Consider moving ZFA term to 'trunk somite' as it is part of the trunk @@ -43954,11 +44081,11 @@ For example, A and B may be gene products and binding of B by A positively regul somite http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + - + @@ -43971,13 +44098,13 @@ For example, A and B may be gene products and binding of B by A positively regul - + GOTAX:0000352 - + ZFA @@ -44080,7 +44207,7 @@ For example, A and B may be gene products and binding of B by A positively regul somitus Wikipedia:Somite - + @@ -44090,12 +44217,12 @@ For example, A and B may be gene products and binding of B by A positively regul - - - - - - + + + + + + A specialized region of ectoderm found between the neural ectoderm (neural plate) and non-neural ectoderm and composed of highly migratory pluripotent cells that delaminate in early embryonic development from the dorsal neural tube and give rise to an astounding variety of differentiated cell types[MP]. EDITOR_NOTE consider including subclasses for pre- and post- migratory (e.g. sheets/paths/streams). @@ -44135,66 +44262,66 @@ For example, A and B may be gene products and binding of B by A positively regul http://upload.wikimedia.org/wikipedia/commons/5/5f/Gray644.png https://upload.wikimedia.org/wikipedia/commons/8/8f/Neural_Crest.png - + - + - + - + - + - + - + XAO https://github.com/obophenotype/uberon/wiki/The-neural-crest - + Hall and others restrict NC to vertebrates but we opt for a less restrictive constraint to avoid inconsistencies when areas such as P1 area of pallium in hagfishes inherit cell lineage from telecephalon-contributing NC cells ISBN:0073040584 - + BTO - + PMID:11523831 - + pre migratory https://github.com/obophenotype/uberon/wiki/The-neural-crest - + PMID:11523831 @@ -44262,7 +44389,7 @@ For example, A and B may be gene products and binding of B by A positively regul crista neuralis Wikipedia:Neural_crest - + @@ -44335,6 +44462,12 @@ For example, A and B may be gene products and binding of B by A positively regul DOI:10.1046/j.1469-7580.2001.19910133.x Graham A. The development and evolution of the pharyngeal arches. J Anat (2001) http://bgee.unil.ch/ + + + + FBbt:00001057 + + @@ -44346,7 +44479,7 @@ For example, A and B may be gene products and binding of B by A positively regul epithelium tubi neuralis; neuroectoderma Wikipedia:Neuroectoderm - + @@ -44382,7 +44515,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -44440,14 +44573,14 @@ For example, A and B may be gene products and binding of B by A positively regul bone marrow http://upload.wikimedia.org/wikipedia/commons/7/74/Gray72-en.svg - + - + FMA MA @@ -44480,7 +44613,7 @@ For example, A and B may be gene products and binding of B by A positively regul medulla ossea BTO:0000141 FMA:9608 - + @@ -44488,7 +44621,7 @@ For example, A and B may be gene products and binding of B by A positively regul medulla ossium BTO:0000141 Wikipedia:Bone_marrow - + @@ -44718,14 +44851,14 @@ For example, A and B may be gene products and binding of B by A positively regul - + - + Anatomical system that is involved in the production of hematopoietic cells. @@ -44770,24 +44903,24 @@ For example, A and B may be gene products and binding of B by A positively regul hematopoietic system - + - + - + FMA - + definitional @@ -45078,7 +45211,7 @@ For example, A and B may be gene products and binding of B by A positively regul epiblastus Wikipedia:Epiblast - + @@ -45158,7 +45291,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Unsegmented field of paraxial mesoderm present posterior to the most recently formed somite pair, from which somites will form. Unsegmented field of paraxial mesoderm present posterior to the most recently formed somite pair, from which somites will form. Kimmel et al, 1995.[TAO] It is reasonable to assume that the proximate invertebrate ancestor of the vertebrates had an amphioxus-like tail bud in its larval stage. This archetypal tail bud would have (...) (3) lacked any component of mesenchyme cells, (4) budded off new mesodermal segments directly, without any intervening zone of presomitic mesoderm (...). Then, early in vertebrate evolution, epithelium-to-mesenchyme interconversions (and the gene networks for effecting them) became prominent features of development. (...) In any case, conspicuous mesenchymal components tended to be added to the vertebrate tail bud itself. In addition, a mesenchymatous presomitic mesoderm (not a part of the tail bud proper) came to intervene between the tail bud and the forming somites.[well established][VHOG] @@ -45183,14 +45316,14 @@ For example, A and B may be gene products and binding of B by A positively regul presomitic mesoderm - + - + Bgee:AN @@ -45420,9 +45553,9 @@ For example, A and B may be gene products and binding of B by A positively regul - - - + + + A region of embryonic ectodermal cells that lie directly above the notochord. During neurulation, they change shape and produce an infolding of the neural plate (the neural fold) that then seals to form the neural tube[XAO]. The earliest recognizable dorsal ectodermal primordium of the central nervous system present near the end of gastrulation before infolding to form the neural keel; consists of a thickened pseudostratified epithelium[ZFA]. The earliest recognizable dorsal ectodermal primordium of the central nervous system present near the end of gastrulation before infolding to form the neural keel; consists of a thickened pseudostratified epithelium. Kimmel et al, 1995.[TAO] (...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord that is located dorsal to the notochord (...).[well established][VHOG] @@ -45454,34 +45587,34 @@ For example, A and B may be gene products and binding of B by A positively regul neural plate https://upload.wikimedia.org/wikipedia/commons/8/8f/Neural_Crest.png - + - + - + - + GOTAX:0000352 - + Wikipedia - + Bgee:AN @@ -45512,6 +45645,14 @@ For example, A and B may be gene products and binding of B by A positively regul ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.28 http://bgee.unil.ch/ + + + + MESH:D054258 + + + https://github.com/biopragmatics/biomappings + @@ -45523,7 +45664,7 @@ For example, A and B may be gene products and binding of B by A positively regul lamina neuralis Wikipedia:Neural_plate - + @@ -45546,7 +45687,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube[GO]. Mesoderm lateral to the neural tube and notochord that is divided into cranial and post-cranial portions. The trunk portions further segment into somites.[AAO] Presently, Cephalochordata, Urochordata, and Vertebrata are placed as subphyla of the phylum Chordata, in which the overall organization of embryonic tissues (dorsal hollow nerve cord, ventral digestive tract, axial notochord, and bilateral paraxial mesoderm) is largely conserved. In contrast, the echinoderms and hemichordates are sister groups of the chordates and they lack the notochord and paraxial mesoderm. Thus, the basic mesodermal organization of vertebrates must have appeared first in the common ancestor of the chordates.[well established][VHOG] @@ -45575,7 +45716,7 @@ For example, A and B may be gene products and binding of B by A positively regul paraxial mesoderm http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + @@ -45588,7 +45729,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Bgee:AN @@ -45648,7 +45789,7 @@ For example, A and B may be gene products and binding of B by A positively regul mesoderma paraxiale Wikipedia:Paraxial_mesoderm - + @@ -45660,7 +45801,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -45704,7 +45845,7 @@ For example, A and B may be gene products and binding of B by A positively regul lateral plate mesoderm http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + @@ -45717,7 +45858,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + EHDAA2 VHOG @@ -45792,7 +45933,7 @@ For example, A and B may be gene products and binding of B by A positively regul mesoderma laminae lateralis Wikipedia:Lateral_plate_mesoderm - + @@ -45801,15 +45942,15 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + - + Bilateral groups of cells consisting of three rows: one row of endocardial precursors medially and two rows of myocardical precursors laterally. The two populations fuse at the midline to form the heart rudiment or cone. should probably be merged with heart rudiment. Bilateral groups of cells consisting of three rows: one row of endocardial precursors medially and two rows of myocardical precursors laterally. The two populations fuse at the midline between 21 and 26 somites to form the heart rudiment or cone. Stainier 2001.[TAO] @@ -45829,15 +45970,15 @@ For example, A and B may be gene products and binding of B by A positively regul heart primordium - + - + - + @@ -45850,19 +45991,19 @@ For example, A and B may be gene products and binding of B by A positively regul - + ZFA - + ZFA - + XAO @@ -45917,8 +46058,8 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + Ventral somitic compartment that is a precursor of the axial skeleton[XAO]. Sclerotomes eventually differentiate into the vertebrae and most of the skull. The caudal (posterior) half of one sclerotome fuses with the rostral (anterior) half of the adjacent one to form each vertebra. From their initial location within the somite, the sclerotome cells migrate medially towards the notochord. These cells meet the sclerotome cells from the other side to form the vertebral body. From this vertebral body, sclerotome cells move dorsally and surround the developing spinal cord, forming the vertebral arch[WP]. Skeletogenic portion of somites.[AAO] The vertebrate sclerotome has no equivalent in amphioxus and is a novelty linked with the evolution of the axial skeleton.[well established][VHOG] @@ -45946,11 +46087,11 @@ For example, A and B may be gene products and binding of B by A positively regul sclerotome http://upload.wikimedia.org/wikipedia/commons/9/96/Gray65.png - + - + @@ -45969,13 +46110,13 @@ For example, A and B may be gene products and binding of B by A positively regul - + VHOG:0000680 - + ZFA @@ -46015,7 +46156,9 @@ For example, A and B may be gene products and binding of B by A positively regul BTO:0006255 - https://orcid.org/0000-0003-4423-4370 + + + https://github.com/biopragmatics/biomappings @@ -46035,7 +46178,7 @@ For example, A and B may be gene products and binding of B by A positively regul sclerotomus Wikipedia:Sclerotome - + @@ -46175,7 +46318,7 @@ For example, A and B may be gene products and binding of B by A positively regul mesenchyma Wikipedia:Mesenchyme - + @@ -46247,7 +46390,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + The part of the coelom in the embryo between the somatopleuric and splanchnopleuric mesoderm; the principal body cavities of the trunk (thoracic, abdominal, and pelvic) arise from this embryonic part of the coelom. consider merging with coelom. TODO - add spatial relationships to halves of LPM. Note the OG places XAO and ZFA coelem terms here. editor note: TODO check ZFA, which appears to be a structure present in adults (...) I regard it unlikely that coeloms of all bilaterian animals are comparable and evolved very early. Considering all these questions, few convincing characters concerning the evolution of body cavities remain to be named. (...) A segmental coelom appears to have evolved at least two times, in Annelida and in Myomerata (Acrania and Craniota).[well established][VHOG] @@ -46263,14 +46406,14 @@ For example, A and B may be gene products and binding of B by A positively regul intraembryonic coelom - + - + Wikipedia @@ -46338,6 +46481,12 @@ For example, A and B may be gene products and binding of B by A positively regul GO:0060562 PMID:12526790 + + + + FBbt:00007474 + + @@ -46589,8 +46738,8 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + A specific region of the lateral mesoderm that will form the primary beating heart tube. In mammals the primary heart field gives rise to the left ventricle. this term denotes the primary heart field; GO:0003128 denotes the superclass of primary and secondary: specific region of the lateral mesoderm into the area which will form the primary beating heart tube[GO:0003138] XAO:0004185 @@ -46603,24 +46752,24 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0004140 primary heart field - + - + - + GO:0003128 - + https://orcid.org/0000-0003-3308-6245 @@ -46679,7 +46828,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + An epithelial tube that will give rise to the mature heart. the paired, longitudinal, endothelial-lined channels formed from the cardiogenic mesoderm in embryonic development; angiogenic cell clusters (aka angioblastic cords) located in a horse-shoe shape configuration in the cardiogenic plate coalesce to form the right and left endocardial heart tubes which then fuse in cephalo-caudal direction to form a single primitive heart tube. AAO:0010411 @@ -46699,14 +46848,14 @@ For example, A and B may be gene products and binding of B by A positively regul heart tube - + - + ZFA-modified @@ -47082,6 +47231,7 @@ For example, A and B may be gene products and binding of B by A positively regul An endothelium that lines the blood vasculature. Other endothelia may line lymph vessels, the heart. + BTO:0000766 CALOHA:TS-2155 EMAPA:35176 @@ -47092,6 +47242,7 @@ For example, A and B may be gene products and binding of B by A positively regul ZFA:0005257 uberon UBERON:0004638 + blood vessel endothelium @@ -47246,6 +47397,12 @@ For example, A and B may be gene products and binding of B by A positively regul We explicitly merge the NCITA terms here NCIT + + + + FBbt:00005317 + + @@ -47325,7 +47482,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + A specialized form of connective tissue in which the extracellular matrix is firm, providing the tissue with resilience, and/or mineralized and that functions in mechanical and structural support.[VSAO]. A specialized form of connective tissue in which the extracellular matrix is firm, providing the tissue with resilience, and/or mineralized and that functions in mechanical and structural support.[VSAO] EMAPA:37744 @@ -47339,7 +47496,7 @@ For example, A and B may be gene products and binding of B by A positively regul Four classes of mineralized tissues are found in vertebrates: bone, cartilage, dentine, and enamel. We think of cartilage and bone as skeletal tissues and of enamel and dentine as dental tissues, but enamel and dentine arose evolutionarily together with bone as skeletal tissues in the dermal skeleton (exoskeleton) of early vertebrates. Scales and teeth of sharks are examples of dermal skeletal elements that are still composed of the three ancient components-enamel, dentine, and bone. Cartilage, on the other hand, provided the basis for the second vertebrate skeletal system, the endoskeleton (Smith and Hall, 1990; Hall, 1998a,b). some invertebrate skeletal tissues have surprisingly bone-like features. Examples include chondrocytes interconnected by cell processes in cephalopod cartilages (Cole and Hall, 2004a,b), and the calcium phosphate layer in the shells of brachiopods (Rodland et al., 2003). However, neither bone nor mineralized cartilage have been found in invertebrates. Editors notes: TODO - develops_from skeletal tissue - + @@ -47352,7 +47509,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + 2012-08-14 VSAO:0000015 VSAO @@ -47391,7 +47548,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Organ consisting of skeletal tissue. Encompasses whole bones, fused bones, cartilaginious elements, teeth, dermal denticles. Organ entity that is typically involved in mechanical support and may have different skeletal tissue compositions at different stages.[VSAO] Organ entity that may have different tissue compositions at different stages and is typically involved in mechanical support.[TAO] @@ -47407,14 +47564,14 @@ For example, A and B may be gene products and binding of B by A positively regul skeletal element - + - + VSAO @@ -47459,7 +47616,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -47498,14 +47655,14 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0004770 articular system - + - + FMA @@ -47760,6 +47917,12 @@ For example, A and B may be gene products and binding of B by A positively regul Anatomical structure that connects two or more adjacent skeletal elements or hardened body parts. http://orcid.org/0000-0002-6601-2165 + + + + FBbt:00005811 + + @@ -47812,6 +47975,12 @@ For example, A and B may be gene products and binding of B by A positively regul A proximal-distal subdivision of the digestive tract. http://orcid.org/0000-0002-6601-2165 + + + + FBbt:00100315 + + @@ -48265,7 +48434,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Mesenchyme that is part of a developing trunk. EFO:0003485 EHDAA2:0002092 @@ -48281,14 +48450,14 @@ For example, A and B may be gene products and binding of B by A positively regul trunk mesenchyme - + - + EHDAA2 @@ -48379,6 +48548,12 @@ For example, A and B may be gene products and binding of B by A positively regul developing anatomical structure + + + + FBbt:00007006 + + @@ -48399,7 +48574,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Multi-tissue structure that arises from the heart rudiment and will become the heart tube. BTO:0006179 EHDAA2:0001512 @@ -48418,14 +48593,14 @@ For example, A and B may be gene products and binding of B by A positively regul primitive heart tube - + - + ZFA @@ -48438,7 +48613,9 @@ For example, A and B may be gene products and binding of B by A positively regul BTO:0006179 - https://orcid.org/0000-0003-4423-4370 + + + https://github.com/biopragmatics/biomappings @@ -48583,7 +48760,7 @@ For example, A and B may be gene products and binding of B by A positively regul membrana basalis Wikipedia:Basement_membrane - + @@ -48599,7 +48776,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + A delimited region of dense mesenchyme within looser mesenchyme. AEO:0000148 EHDAA2_RETIRED:0003148 @@ -48609,7 +48786,7 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0005856 developing mesenchymal condensation - + @@ -48628,7 +48805,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + AEO-modified-relation @@ -48721,7 +48898,7 @@ For example, A and B may be gene products and binding of B by A positively regul skeleton axiale Wikipedia:Axial_skeleton - + @@ -48733,7 +48910,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + The notochordal plate is the dorsal part of the notochordal process when the ventral portion breaks down. It is continuous laterally with the endoderm that composes the roof of the primitive foregut and is in contact dorsally with the neural tube. The folding off of the notochordal plate gives rise to the notochord. TODO - check ordering; awaiting confirmation from JB The notochordal plate is the dorsal part of the notochordal process when the ventral portion breaks down. It is continuous laterally with the endoderm that composes the roof of the primitive foregut and is in contact dorsally with the neural tube. The folding off of the notochordal plate gives rise to the notochord. [Carson_JL, Dehart_DB, Developmental_Dynamics_(1994)_201:_260-278, Gesteland_K_and_Schoenwolf_GC, Inagaki_T, Morphogenesis_of_the_murine_node_and_notochordal_plate, The_prechordal_plate, Vrablic_T, see_Mueller_F_and_O'Rahilly_R, the_rostral_end_of_the_notochord_and_nearby_median_features_in_staged_human_embryos._Cells_Tissues_Organs_(2003)_173:_1-20_and_Sulik_K][VHOG] @@ -48748,7 +48925,7 @@ For example, A and B may be gene products and binding of B by A positively regul notochordal plate - + @@ -48761,7 +48938,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + EHDAA2 @@ -48798,7 +48975,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + A midline cellular cord formed from the migration of mesenchymal cells from the primitive knot. EHDAA2:0001279 EHDAA:224 @@ -48815,14 +48992,14 @@ For example, A and B may be gene products and binding of B by A positively regul The notochordal process grows cranially until it reaches the prechordal plate, the future site of the mouth. In this area the ectoderm is attached directly to the endoderm without intervening mesoderm. This area is known as the oropharyngeal membrane, and it will break down to become the mouth. At the other end of the primitive streak the ectoderm is also fused directly to the endoderm; this is known as the cloacal membrane (proctodeum), or primordial anus. notochordal process - + - + EHDAA2 @@ -49529,7 +49706,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + A hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood or analogs[GO,modified]. note we reserve the subclass 'heart' from the vertebrate multi-chambered heart. 'The first heart-like organ is believed to have appeared 500my ago in an ancestral bilaterian'. Amniotes: four-chambered heart. Amphibians: two atria, one ventricle, pulmonary; fish: single atrium and ventricle; amphioxus: tubular, non-striated, closed, unidirectional; ascidians: tubular, striated, open, bidirectional; arthropods: tubular, open; C elegans: contractile pharynx; Cnideria: striated muscle cells associated with gastrodermis SPD:0000130 @@ -49544,14 +49721,14 @@ For example, A and B may be gene products and binding of B by A positively regul Gene notes: Bmp, Nkx, Gata primary circulatory organ - + - + GO uses blood circulation generically to include the haemolymphatic fluid of arthropods @@ -49641,7 +49818,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -49658,14 +49835,14 @@ For example, A and B may be gene products and binding of B by A positively regul presumptive segmental plate - + - + https://github.com/obophenotype/uberon/wiki/The-neural-crest EDHAA2 @@ -49764,7 +49941,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -49790,7 +49967,7 @@ For example, A and B may be gene products and binding of B by A positively regul presumptive paraxial mesoderm - + @@ -49806,7 +49983,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + https://github.com/obophenotype/uberon/issues/1277 @@ -49882,7 +50059,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Mesenchyme with little extracellular matrix. AEO:0000146 EHDAA2:0003146 @@ -49890,7 +50067,7 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0007524 dense mesenchyme tissue - + @@ -49903,7 +50080,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + AEO @@ -49993,6 +50170,12 @@ For example, A and B may be gene products and binding of B by A positively regul FBbt:00005426 http://flybase.org/reports/FBrf0178740.html + + + + FBbt:00005426 + + @@ -50000,7 +50183,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Anatomical system that consists of all blood and lymph vessels. consider merging with vasculature @@ -50019,14 +50202,14 @@ For example, A and B may be gene products and binding of B by A positively regul vascular system - + - + MA @@ -50066,7 +50249,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -50083,14 +50266,14 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0009142 entire embryonic mesenchyme - + - + EHDAA2 @@ -50146,7 +50329,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + EHDAA2:0002094 trunk and cervical paraxial mesenchyme uberon @@ -50154,14 +50337,14 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0009618 trunk paraxial mesoderm - + - + EHDAA2 @@ -50183,7 +50366,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + EFO:0003704 TAO:0005041 ZFA:0005041 @@ -50193,14 +50376,14 @@ For example, A and B may be gene products and binding of B by A positively regul anterior lateral plate mesoderm - + - + ZFA @@ -50258,6 +50441,12 @@ For example, A and B may be gene products and binding of B by A positively regul An anatomical structure that has more than one cell as a part. CARO:0010000 + + + + FBbt:00100313 + + @@ -50334,7 +50523,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -50354,14 +50543,14 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0010210 blood clot - + - + BTO @@ -50483,8 +50672,8 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + Anatomical cluster consisting of the skeletal elements (i.e. bone elements, cartilage elements, cartilage condensations) that are part of an individual subdivision of the organism. Excludes joints. Anatomical cluster consisting of the skeletal elements that are part of the skeleton.[VSAO] FMA:23879 @@ -50497,11 +50686,11 @@ For example, A and B may be gene products and binding of B by A positively regul subdivision of skeleton - + - + @@ -50514,13 +50703,13 @@ For example, A and B may be gene products and binding of B by A positively regul - + UBERONREF:0000003 - + VSAO @@ -50591,7 +50780,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Subdivision of the skeletal system which consists of the postcranial axial skeleton plus associated joints. axial skeletal system FMA:302077 @@ -50601,7 +50790,7 @@ For example, A and B may be gene products and binding of B by A positively regul postcranial axial skeletal system http://purl.obolibrary.org/obo/uberon/docs/The-axial-skeleton - + @@ -50614,7 +50803,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + cjm @@ -50647,12 +50836,14 @@ For example, A and B may be gene products and binding of B by A positively regul + FBbt:00007330 FMA:67509 SCTID:91690000 uberon UBERON:0011216 + organ system subdivision @@ -50668,6 +50859,12 @@ For example, A and B may be gene products and binding of B by A positively regul A subdivision of an anatomical system. http://orcid.org/0000-0002-6601-2165 + + + + FBbt:00007330 + + @@ -50879,7 +51076,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -50901,7 +51098,7 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0012429 hematopoietic tissue - + @@ -50914,7 +51111,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + defitional @@ -51077,7 +51274,6 @@ For example, A and B may be gene products and binding of B by A positively regul The region of the organism associated with the visceral organs. - Cardinal body part, which consists of a maximal set of diverse subclasses of organ and organ part spatially associated with the vertebral column and ribcage. Examples: There is only one body proper[FMA:231424]. AEO:0000103 BTO:0001489 @@ -51087,7 +51283,6 @@ For example, A and B may be gene products and binding of B by A positively regul body whole body UBERON:0013702 - body proper @@ -51235,6 +51430,12 @@ For example, A and B may be gene products and binding of B by A positively regul FBC:DOS FBbt:00007278 + + + + FBbt:00007278 + + @@ -51488,7 +51689,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -51511,7 +51712,7 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0016887 entire extraembryonic component - + @@ -51524,7 +51725,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + AEO @@ -51650,6 +51851,12 @@ For example, A and B may be gene products and binding of B by A positively regul Material anatomical entity consisting of multiple anatomical structures that are not connected to each other. CARO:0020000 + + + + FBbt:00007276 + + @@ -52026,6 +52233,24 @@ For example, A and B may be gene products and binding of B by A positively regul + + + + + + + + + + + + + + + + + + @@ -52056,6 +52281,16 @@ For example, A and B may be gene products and binding of B by A positively regul + + + + + + + + + + diff --git a/src/ontology/subsets/blood_and_immune_upper_slim.tsv b/src/ontology/subsets/blood_and_immune_upper_slim.tsv index bc02e85e2..ed97b6166 100644 --- a/src/ontology/subsets/blood_and_immune_upper_slim.tsv +++ b/src/ontology/subsets/blood_and_immune_upper_slim.tsv @@ -1,395 +1,392 @@ ?x ?label -_:B401aa5d3X2D71a9X2D4aa1X2Da48dX2Dfa166a9c6ddagenid1014 -_:B401aa5d3X2D71a9X2D4aa1X2Da48dX2Dfa166a9c6ddagenid1027 -_:B401aa5d3X2D71a9X2D4aa1X2Da48dX2Dfa166a9c6ddagenid1041 -_:B401aa5d3X2D71a9X2D4aa1X2Da48dX2Dfa166a9c6ddagenid1057 -_:B401aa5d3X2D71a9X2D4aa1X2Da48dX2Dfa166a9c6ddagenid1075 -_:B401aa5d3X2D71a9X2D4aa1X2Da48dX2Dfa166a9c6ddagenid1082 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+_:Bfc26b7c9X2D6e5eX2D4e75X2D81bcX2D5596fb9a64a9genid761 +_:Bfc26b7c9X2D6e5eX2D4e75X2D81bcX2D5596fb9a64a9genid776 +_:Bfc26b7c9X2D6e5eX2D4e75X2D81bcX2D5596fb9a64a9genid829 +_:Bfc26b7c9X2D6e5eX2D4e75X2D81bcX2D5596fb9a64a9genid846 +_:Bfc26b7c9X2D6e5eX2D4e75X2D81bcX2D5596fb9a64a9genid866 +_:Bfc26b7c9X2D6e5eX2D4e75X2D81bcX2D5596fb9a64a9genid881 +_:Bfc26b7c9X2D6e5eX2D4e75X2D81bcX2D5596fb9a64a9genid936 +_:Bfc26b7c9X2D6e5eX2D4e75X2D81bcX2D5596fb9a64a9genid967 "continuant" "occurrent" "independent continuant" @@ -547,7 +544,6 @@ _:B401aa5d3X2D71a9X2D4aa1X2Da48dX2Dfa166a9c6ddagenid970 "acidophilic cytoplasm" "basophilic cytoplasm" "polychromatophilic cytoplasm" - "increased nucleus size" "cartwheel heterochromatin" "bone marrow hematopoietic cell" "peripheral blood mononuclear cell" @@ -966,6 +962,7 @@ _:B401aa5d3X2D71a9X2D4aa1X2Da48dX2Dfa166a9c6ddagenid970 "exocytic process" "extracellular vesicle biogenesis" "export from cell" + "defense response to symbiont" "organic substance biosynthetic process" "regulation of leukocyte differentiation" "mitotic cell cycle process" @@ -1011,15 +1008,10 @@ _:B401aa5d3X2D71a9X2D4aa1X2Da48dX2Dfa166a9c6ddagenid970 "quality" "morphology" "shape" - "qualitative" - "deviation (from_normal)" - "size" "structure" "maturity" "branched" "circular" - "normal" - "increased size" "elliptic" "physical quality" "physical object quality" @@ -1056,13 +1048,12 @@ _:B401aa5d3X2D71a9X2D4aa1X2Da48dX2Dfa166a9c6ddagenid970 "quality of a substance" "3-D shape" "tubular" - "increased quality" - "increased object quality" "superelliptic" "acidophilic" "nucleated" "disconnected" "polymeric" + "high nuclear/cytoplasmic ratio" "anatomical structure quality" "anatomical histological quality" "neutrophillic" diff --git a/src/ontology/subsets/eye_upper_slim.json b/src/ontology/subsets/eye_upper_slim.json index 45ef90be0..8b2e399be 100644 --- a/src/ontology/subsets/eye_upper_slim.json +++ b/src/ontology/subsets/eye_upper_slim.json @@ -4,9 +4,9 @@ "meta" : { "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2002/07/owl#versionInfo", - "val" : "2024-01-04" + "val" : "2024-02-13" } ], - "version" : "http://purl.obolibrary.org/obo/cl/releases/2024-01-04/subsets/eye_upper_slim.owl" + "version" : "http://purl.obolibrary.org/obo/cl/releases/2024-02-13/subsets/eye_upper_slim.owl" }, "nodes" : [ { "id" : "http://purl.obolibrary.org/obo/BFO_0000002", @@ -731,7 +731,7 @@ "xrefs" : [ "CARO:mah" ] }, "comments" : [ "The definition of cell is intended to represent all cells, and thus a cell is defined as a material entity and not an anatomical structure, which implies that it is part of an organism (or the entirety of one)." ], - "subsets" : [ "http://purl.obolibrary.org/obo/ubprop#_upper_level" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/ubprop#_upper_level" ], "xrefs" : [ { "val" : "CALOHA:TS-2035" }, { @@ -767,6 +767,7 @@ "lbl" : "neuronal receptor cell", "type" : "CLASS", "meta" : { + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "neuronal receptor cell (sensu Animalia)" @@ -795,7 +796,10 @@ }, { "id" : "http://purl.obolibrary.org/obo/CL_0000030", "lbl" : "glioblast", - "type" : "CLASS" + "type" : "CLASS", + "meta" : { + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] + } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000031", "lbl" : "neuroblast (sensu Vertebrata)", @@ -805,6 +809,7 @@ "val" : "A cell that will develop into a neuron often after a migration phase.", "xrefs" : [ "GOC:NV", "http://en.wikipedia.org/wiki/Neuroblast" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "neuroblast" @@ -825,7 +830,7 @@ "xrefs" : [ "GOC:tfm", "MESH:D013234" ] }, "comments" : [ "This term applies to metazoan. For plant stem cells, consider using PO:0004011 ‘initial cell’ or its parent PO:0004010 ‘meristematic cell’." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "animal stem cell" @@ -850,7 +855,7 @@ "xrefs" : [ "GOC:add", "GOC:dsd", "GOC:tfm", "PMID:19022770", "http://en.wikipedia.org/wiki/Hematopoietic_stem_cell" ] }, "comments" : [ "Markers differ between species, and two sets of markers have been described for mice. HSCs are reportedly CD34-positive, CD45-positive, CD48-negative, CD150-positive, CD133-positive, and CD244-negative." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "blood forming stem cell" @@ -890,7 +895,7 @@ "val" : "A progenitor cell committed to the erythroid lineage.", "xrefs" : [ "GOC:add", "ISBN:0721601464" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003000", "pred" : "hasRelatedSynonym", @@ -952,7 +957,7 @@ "xrefs" : [ "GOC:add", "ISBN:0878932437", "MESH:D023461" ] }, "comments" : [ "This cell type is intended to be compatible with any vertebrate common myeloid progenitor. For mammalian CMP known to be CD34-positive, please use the term 'common myeloid progenitor, CD34-positive' (CL_0001059)." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "common myeloid precursor" @@ -1006,7 +1011,7 @@ "xrefs" : [ "GOC:add", "GOC:dsd", "GOC:tfm", "MESH:D055015", "PMID:16647566", "http://en.wikipedia.org/wiki/Megakaryocyte-erythroid_progenitor_cell" ] }, "comments" : [ "MEPs are reportedly CD19-negative, CD34-negative, CD45RA-negative, CD110-positive, CD117-positive, and SCA1-negative and reportedly express the transcription factors GATA-1 and NF-E2." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "CFU-EM" @@ -1063,6 +1068,7 @@ "xrefs" : [ "SANBI:mhl" ] }, "comments" : [ "define using PATO mulit-potent or oligopotent?" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "blast cell" @@ -1104,7 +1110,7 @@ "xrefs" : [ "ISBN:0517223651", "MESH:D005347", "http://en.wikipedia.org/wiki/Fibroblast" ] }, "comments" : [ "These cells may be vimentin-positive, fibronectin-positive, fsp1-positive, MMP-1-positive, collagen I-positive, collagen III-positive, and alpha-SMA-negative." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { "val" : "BTO:0000452" }, { @@ -1130,7 +1136,7 @@ "val" : "A cell that is usually found in a two-dimensional sheet with a free surface. The cell has a cytoskeleton that allows for tight cell to cell contact and for cell polarity where apical part is directed towards the lumen and the basal part to the basal lamina.", "xrefs" : [ "FB:ma", "GOC:tfm", "MESH:D004847" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "epitheliocyte" @@ -1165,7 +1171,7 @@ "val" : "An endothelial cell that lines the vasculature.", "xrefs" : [ "GOC:tfm" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cuboidal endothelial cell of vascular tree" @@ -1184,7 +1190,7 @@ "val" : "A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube.", "xrefs" : [ "GO:0002065", "https://orcid.org/0000-0001-5208-3432" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" @@ -1195,6 +1201,7 @@ "lbl" : "squamous epithelial cell", "type" : "CLASS", "meta" : { + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "CALOHA:TS-1249" } ] @@ -1208,7 +1215,7 @@ "val" : "A flattened epithelial cell of mesenchymal origin that lines the serous cavity.", "xrefs" : [ "GOC:tfm", "ISBN:0721662544" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "mesotheliocyte" @@ -1230,7 +1237,7 @@ "val" : "A cell found predominately in the blood.", "xrefs" : [ "GOC:add", "GOC:tfm" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim" ], "xrefs" : [ { "val" : "FMA:62844" }, { @@ -1240,7 +1247,10 @@ }, { "id" : "http://purl.obolibrary.org/obo/CL_0000095", "lbl" : "neuron associated cell", - "type" : "CLASS" + "type" : "CLASS", + "meta" : { + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] + } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000099", "lbl" : "interneuron", @@ -1250,7 +1260,7 @@ "val" : "Most generally any neuron which is not motor or sensory. Interneurons may also refer to neurons whose axons remain within a particular brain region as contrasted with projection neurons which have axons projecting to other brain regions.", "xrefs" : [ "GOC:tfm", "MESH:D007395" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { "val" : "BTO:0003811" }, { @@ -1295,7 +1305,7 @@ "val" : "A type of interneuron that has two neurites, usually an axon and a dendrite, extending from opposite poles of an ovoid cell body.", "xrefs" : [ "GOC:tfm", "ISBN:0444009442" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#BDS_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#BDS_subset", "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "FMA:67282" } ] @@ -1310,7 +1320,7 @@ "xrefs" : [ "GOC:tfm", "MESH:D042783", "PMID:21275341", "http://en.wikipedia.org/wiki/Endothelial_cell", "https://sourceforge.net/tracker/?func=detail&atid=440764&aid=3364936&group_id=36855" ] }, "comments" : [ "From FMA: 9.07.2001: Endothelial cell has always been classified as a kind of epithelial cell, specifically a squamous cell but that is not true. First, endothelial cell can either be squamous or cuboidal (e.g. high-endothelial cell) and secondly, it has different embryological derivation (mesodermal) than a true epithelial cell (ectodermal and endodermal). The basis for present classification is the fact that it comprises the outermost layer or lining of anatomical structures (location-based) but a better structural basis for the differentia is the cytoskeleton of the cell. Endothelial cell has vimentin filaments while an epithelial cell has keratin filaments. [Onard]." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "endotheliocyte" @@ -1334,7 +1344,10 @@ }, { "id" : "http://purl.obolibrary.org/obo/CL_0000123", "lbl" : "neuron associated cell (sensu Vertebrata)", - "type" : "CLASS" + "type" : "CLASS", + "meta" : { + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] + } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000125", "lbl" : "glial cell", @@ -1345,7 +1358,7 @@ "xrefs" : [ "MESH:D009457" ] }, "comments" : [ "Not all glial cells develop from glioblasts, with microglia developing from the mesoderm instead. See https://github.com/obophenotype/cell-ontology/issues/1571" ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "neuroglial cell" @@ -1372,6 +1385,7 @@ "val" : "A neuroglial cell of ectodermal origin, i.e., the astrocytes and oligodendrocytes considered together.", "xrefs" : [ "GOC:tfm", "ISBN:0721662544" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "macrogliocyte" @@ -1399,7 +1413,7 @@ "xrefs" : [ "GOC:dsd", "GOC:tfm", "MESH:D001253", "PMID:11746784", "PMID:12162730", "PMID:12898703", "PMID:20942978", "http://en.wikipedia.org/wiki/Astrocyte" ] }, "comments" : [ "Astrocytes are reportedly CD68-negative, CD121a-positive, CD184-positive, CD192-positive, CRF-positive, EGFR-positive, GFAP-positive, GLUT1-positive, MBP-negative, and NGFR-positive." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "astrocytic glia" @@ -1425,7 +1439,7 @@ "val" : "An hexagonal, flattened, mitochondria-rich endothelial cell that forms a monolayer on the posterior surface of the cornea (the corneal endothelium). Corneal endothelial cells are derived from the neural crest and are responsible for keeping the cornea transparent by maintaining the tissue in a semi-dry state through the action of their ionic pumps and tight junction barrier.", "xrefs" : [ "GOC:tfm", "PMID:21976958", "PMID:23284695", "PMID:34741068", "PMID:36769303" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { "val" : "CALOHA:TS-0172" }, { @@ -1460,6 +1474,7 @@ "xrefs" : [ "FB:ma", "GOC:dsd", "PMCID:PMC2613570", "PMID:10102814", "PMID:16923606", "PMID:17986482", "PMID:19960544", "http://en.wikipedia.org/wiki/Mesenchymal_stem_cell", "http://www.copewithcytokines.de/cope.cgi?key=mesenchymal%20stem%20cells" ] }, "comments" : [ "Many but not all mesenchymal cells derive from the mesoderm. MSCs are reportedly CD3-negative, CD4-negative, CD5-negative, CD8-negative, CD11a-negative, CD11b-negative, CD14-negative, CD19-negative, CD29-positive, CD31-negative, CD34-negative, CD38-negative, CD40-negative, CD44-positive, CD45-negative, CD49-positive, CD54-positive, CD66b-negative, CD79a-negative, CD80-negative, CD102-positive, CD106-positive, CD117-positive, CD121a-positive, CD121b-positive, CD123-positive, CD124-positive, CD133-negative, CD146-positive, CD166-positive, CD271-positive, B220-negative, Gr1-negative, MHCI-positive, MHCII-negative, SSEA4-negative, sca1-positive, Ter119-negative, and glycophorin A-negative. Cultured MSCs are capable of producing stem cell factor, IL7, IL8, IL11, TGF-beta, cofilin, galectin-1, laminin-receptor 1, cyclophilin A, and MMP-2." ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "bone marrow stromal cells" @@ -1548,7 +1563,7 @@ "val" : "A pigment cell derived from the neural crest. Contains melanin-filled pigment granules, which gives a brown to black appearance.", "xrefs" : [ "SANBI:mhl" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "melanophore" @@ -1588,6 +1603,7 @@ "val" : "A cell that specializes in controlled release of one or more substances.", "xrefs" : [ "GOC:tfm", "ISBN:0721662544" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "BTO:0003659" }, { @@ -1602,7 +1618,8 @@ "definition" : { "val" : "A cell whose primary function is to shorten.", "xrefs" : [ "FB:ma" ] - } + }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000187", @@ -1613,6 +1630,7 @@ "val" : "A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns.", "xrefs" : [ "MESH:D032342" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "muscle fiber" @@ -1647,7 +1665,7 @@ "val" : "A non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels. They develop from specialized myoblasts (smooth muscle myoblast).", "xrefs" : [ "MESH:D032389", "PMID:9315361", "http://en.wikipedia.org/wiki/Smooth_muscle_cell" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "non-striated muscle cell" @@ -1700,6 +1718,7 @@ "val" : "A cell specialized to detect and transduce light.", "xrefs" : [ "MESH:D010786" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "BTO:0001060" }, { @@ -1782,6 +1801,7 @@ "val" : "A cell of the middle germ layer of the embryo.", "xrefs" : [ "MESH:D008648" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "mesoblast" @@ -1819,7 +1839,7 @@ "val" : "A red blood cell. In mammals, mature erythrocytes are biconcave disks containing hemoglobin whose function is to transport oxygen.", "xrefs" : [ "GOC:tfm", "MESH:D004912" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "RBC" @@ -1844,6 +1864,7 @@ "lbl" : "eukaryotic cell", "type" : "CLASS", "meta" : { + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "MESH:D005057" } ] @@ -1853,7 +1874,7 @@ "lbl" : "eye photoreceptor cell", "type" : "CLASS", "meta" : { - "subsets" : [ "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" @@ -2043,6 +2064,7 @@ "val" : "A precursor cell destined to differentiate into smooth muscle myocytes.", "xrefs" : [ "GOC:tfm", "MESH:D032390" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "myoblast, smooth muscle", @@ -2080,7 +2102,10 @@ }, { "id" : "http://purl.obolibrary.org/obo/CL_0000529", "lbl" : "pigmented epithelial cell", - "type" : "CLASS" + "type" : "CLASS", + "meta" : { + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] + } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000540", "lbl" : "neuron", @@ -2091,7 +2116,7 @@ "xrefs" : [ "MESH:D009474", "http://en.wikipedia.org/wiki/Neuron" ] }, "comments" : [ "These cells are also reportedly CD4-negative and CD200-positive. They are also capable of producing CD40L and IFN-gamma." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "nerve cell" @@ -2142,7 +2167,7 @@ "val" : "An immature, nucleated erythrocyte occupying the stage of erythropoeisis that follows formation of erythroid progenitor cells. This cell is CD71-positive, has both a nucleus and a nucleolus, and lacks hematopoeitic lineage markers.", "xrefs" : [ "ISBN:0721601464", "PMID:1638021" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "rubriblast", @@ -2266,7 +2291,7 @@ "xrefs" : [ "GOC:dsd", "GOC:tfm", "ISBN:0721601464" ] }, "comments" : [ "Lineage negative is described here as CD2-negative, CD3-negative, CD4-negative, CD5-negative, CD8a-negative, CD14-negative, CD19-negative, CD20-negative, CD56-negative, Ly6g-negative, and Ter119-negative." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "CFU-Meg", @@ -2326,7 +2351,7 @@ "xrefs" : [ "ISBN:0721601464", "MESH:D008533", "PMID:31043076", "http://en.wikipedia.org/wiki/Megakaryocyte" ] }, "comments" : [ "Megakaryocytes are reportedly CD181-positive and CD182-positive." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "megacaryocyte" @@ -2358,7 +2383,7 @@ "val" : "An immature erythrocyte that changes the protein composition of its plasma membrane by exosome formation and extrusion. The types of protein removed differ between species though removal of the transferrin receptor is apparent in mammals and birds.", "xrefs" : [ "GOC:add", "GOC:tfm", "PMID:15946868", "PMID:2037622" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "BTO:0001173" }, { @@ -2376,7 +2401,7 @@ "val" : "Interneuron of the vertebrate retina. They integrate, modulate, and interpose a temporal domain in the visual message presented to the retinal ganglion cells, with which they synapse in the inner plexiform layer. They lack large axons.", "xrefs" : [ "GOC:tfm", "MESH:D025042", "WikipediaVersioned:Amacrine_cell&oldid=1023572246" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "amacrine neuron" @@ -2428,7 +2453,7 @@ "val" : "One of the two photoreceptor cell types in the vertebrate retina. In cones the photopigment is in invaginations of the cell membrane of the outer segment. Cones are less sensitive to light than rods, but they provide vision with higher spatial and temporal acuity, and the combination of signals from cones with different pigments allows color vision.", "xrefs" : [ "MESH:D017949" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "cone", @@ -2455,7 +2480,7 @@ "val" : "An epithelial cell of the cornea.", "xrefs" : [ "GOC:tfm" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "epithelial cell of cornea", @@ -2482,7 +2507,7 @@ "val" : "One of the two photoreceptor cell types of the vertebrate retina. In rods the photopigment is in stacks of membranous disks separate from the outer cell membrane. Rods are more sensitive to light than cones, but rod mediated vision has less spatial and temporal resolution than cone vision.", "xrefs" : [ "MESH:D017948" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "rod", @@ -2509,7 +2534,7 @@ "val" : "Astrocyte-like radial glial cell that extends vertically throughout the retina, with the nucleus are usually in the middle of the inner nuclear layer.", "xrefs" : [ "GOC:NV", "PMID:21911394" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#MISSPELLING", "pred" : "hasExactSynonym", @@ -2538,7 +2563,7 @@ "definition" : { "val" : "A neuron that is capable of some neurotansmission by glutamate secretion." }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { "val" : "FBbt:00100291" }, { @@ -2557,7 +2582,8 @@ "definition" : { "val" : "A non-terminally differentiated cell that is capable of developing into a muscle cell.", "xrefs" : [ "GOC:add" ] - } + }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000681", @@ -2569,6 +2595,7 @@ "xrefs" : [ "GOC:dph" ] }, "comments" : [ "Unlike that of mammals, the brain of adult teleost fish exhibits an intense and widespread neurogenic activity as a result of the persistence of\nradial glial cells acting as neural progenitors throughout life." ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "forebrain radial glial cell" @@ -2618,7 +2645,7 @@ "val" : "The set of neurons that receives neural inputs via bipolar, horizontal and amacrine cells. The axons of these cells make up the optic nerve.", "xrefs" : [ "GOC:dph" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "gangliocyte" @@ -2657,7 +2684,7 @@ "val" : "A neuron that laterally connects other neurons in the inner nuclear layer of the retina.", "xrefs" : [ "ISBN:0195088433" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "horizontal cell" @@ -2689,7 +2716,7 @@ "val" : "A bipolar neuron found in the retina and having connections with photoreceptors cells and neurons in the inner plexiform layer.", "xrefs" : [ "PMID:14689473" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003000", "pred" : "hasRelatedSynonym", @@ -2720,6 +2747,7 @@ "val" : "A cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage.", "xrefs" : [ "GOC:add" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "BTO:0001441" }, { @@ -2738,7 +2766,7 @@ "xrefs" : [ "GOC:add", "GOC:tfm" ] }, "comments" : [ "Note that in FMA erythropoietic cells are types of nucleated erythrocytes and thus don't include erythrocytes." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "erythropoietic cell" @@ -2764,7 +2792,7 @@ "val" : "A nucleated precursor of an erythrocyte that lacks hematopoietic lineage markers.", "xrefs" : [ "GOC:add", "ISBN:0721601464", "PMID:18174176" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "normoblast" @@ -2789,7 +2817,7 @@ "xrefs" : [ "GOC:add", "GOC:tfm", "PMID:19022770" ] }, "comments" : [ "Markers differ between mouse and human." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "MPP" @@ -2817,7 +2845,7 @@ "xrefs" : [ "GOC:add", "GOC:tfm", "PMID:19022770" ] }, "comments" : [ "Note that this is a class of cell types, not an identified single cell type." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "myeloid progenitor cell" @@ -2843,6 +2871,7 @@ "val" : "A cell of a hematopoietic lineage.", "xrefs" : [ "GOC:add", "GO_REF:0000031" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "haematopoietic cell" @@ -2954,6 +2983,7 @@ "xrefs" : [ "GOC:dsd", "GOC:tfm", "PMID:12768659" ] }, "comments" : [ "These cells are reportedly CD31-positive, CD34-positive, CD144-positive, TAL1-positive." ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "vascular endothelial cell" @@ -3047,7 +3077,7 @@ "xrefs" : [ "PMID:15106942" ] }, "comments" : [ "In a consensus model of unidirectional secretion, aqueous humour is formed by transferring solute, principally NaCl, from stroma to posterior chamber, with water passively following the osmotic gradient. Unidirectional secretion comprises three sequential steps. First, NaCl is transferred from the stromal interstitium into the pigmented ciliary epithelial (PE) cells. Second, solute passes from the PE into the non-pigmented ciliary epithelial (NPE) cells through gap junctions. Finally, NPE cells release Na+ and Cl− into the aqueous humour." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "PE cell", @@ -3077,7 +3107,7 @@ "xrefs" : [ "GOC:tfm", "PMID:15106942" ] }, "comments" : [ "In a consensus model of unidirectional secretion, aqueous humour is formed by transferring solute, principally NaCl, from stroma to posterior chamber, with water passively following the osmotic gradient. Unidirectional secretion comprises three sequential steps. First, NaCl is transferred from the stromal interstitium into the pigmented ciliary epithelial (PE) cells. Second, solute passes from the PE into the non-pigmented ciliary epithelial (NPE) cells through gap junctions. Finally, NPE cells release Na+ and Cl− into the aqueous humour." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "NPE cell", @@ -3110,6 +3140,7 @@ "val" : "A cell that is part of the nervous system.", "xrefs" : [ "GOC:tfm", "ISBN:0618947256" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "CALOHA:TS-2040" }, { @@ -3132,6 +3163,7 @@ "val" : "A cell of the supporting or framework tissue of the body, arising chiefly from the embryonic mesoderm and including adipose tissue, cartilage, and bone.", "xrefs" : [ "GOC:tfm", "ISBN:0618947256" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "CALOHA:TS-2096" }, { @@ -3180,7 +3212,7 @@ "val" : "A keratocyte is a specialized fibroblast residing in the cornea stroma that has a flattened, dendritic morphology; located between the lamellae with a large flattened nucleus, and lengthy processes which communicate with neighboring cells. This corneal layer, representing about 85-90% of corneal thickness, is built up from highly regular collagenous lamellae and extracellular matrix components. Keratocytes play the major role in keeping it transparent, healing its wounds, and synthesizing its components. This cell type secretes collagen I, V, VI, and keratan sulfate.", "xrefs" : [ "GOC:tfm", "ISBN:9780702029585" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "corneal fibroblast" @@ -3296,7 +3328,7 @@ "val" : "A blood vessel endothelial cell that is part of the retina.", "xrefs" : [ "GOC:tfm" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" @@ -3317,7 +3349,7 @@ "val" : "An epithelial cell of the retinal pigmented epithelium.", "xrefs" : [ "GOC:tfm" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { "val" : "BTO:0004910" }, { @@ -3397,7 +3429,8 @@ "definition" : { "val" : "Any hematopoietic cell that is a precursor of some other hematopoietic cell type.", "xrefs" : [ "GOC:dos" ] - } + }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0008007", @@ -3420,7 +3453,7 @@ "definition" : { "val" : "A non-polarised cell precursor cell that is part of some mesenchyme, is associated with the cell matrix but is not connected to other cells and is capable of migration." }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "mesenchyme cell" @@ -3491,7 +3524,8 @@ "definition" : { "val" : "A cell of the neural crest. Neural crest cells are multipotent. Premigratory neural crest cells are found at the neural plate boarder, some of which will undergo ectomesynchymal transition and delamination to form migratory neural crest cells.", "xrefs" : [ "https://orcid.org/0000-0001-5208-3432", "https://orcid.org/0000-0002-9900-7880" ] - } + }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0011026", @@ -3502,6 +3536,7 @@ "val" : "A precursor cell that has a tendency to differentiate into a specific type of cell. They are descendants of stem cells, only they are more constrained in their differentiation potential or capacity for self-renewal, and are often more limited in both senses.", "xrefs" : [ "ISBN:978-1-62808-994-3", "https://doi.org/10.1016/B978-0-12-409503-8.00002-0" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0001-5208-3432" @@ -3528,7 +3563,8 @@ "val" : "A cell that, by division or terminal differentiation, can give rise to other cell types.", "xrefs" : [ "GOC:dos" ] }, - "comments" : [ "Work is needed on GO 'cell differentiation' before it is clear whether the equivalent class definition 'native cell' that capable_of some 'cell differentiation' works. Also, may want to consider merging this with non-terminally differentiated cell." ] + "comments" : [ "Work is needed on GO 'cell differentiation' before it is clear whether the equivalent class definition 'native cell' that capable_of some 'cell differentiation' works. Also, may want to consider merging this with non-terminally differentiated cell." ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0017502", @@ -3585,23 +3621,6 @@ "val" : "2009-12-28T04:25:23Z" } ] } - }, { - "id" : "http://purl.obolibrary.org/obo/CL_0017505", - "lbl" : "increased nucleus size", - "type" : "CLASS", - "meta" : { - "definition" : { - "val" : "A nucleus size quality which is relatively high compared to the amount of cytoplasm present in the same cell.", - "xrefs" : [ "GOC:tfm" ] - }, - "basicPropertyValues" : [ { - "pred" : "http://purl.org/dc/terms/contributor", - "val" : "https://orcid.org/0000-0003-1980-3228" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", - "val" : "2009-12-23T10:53:24Z" - } ] - } }, { "id" : "http://purl.obolibrary.org/obo/CL_1000432", "lbl" : "conjunctival epithelial cell", @@ -3611,7 +3630,7 @@ "val" : "An epithelial cell that is part of the conjunctiva.", "xrefs" : [ "GOC:tfm" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#eye_upper_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#eye_upper_slim" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "epithelial cell of conjunctiva", @@ -3630,7 +3649,7 @@ "val" : "A smooth muscle cell that is part of the ciliary body.", "xrefs" : [ "GOC:tfm" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#eye_upper_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#eye_upper_slim" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "smooth muscle cell of ciliary body", @@ -4221,7 +4240,7 @@ "type" : "CLASS", "meta" : { "definition" : { - "val" : "A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex).", + "val" : "A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex).", "xrefs" : [ "GOC:pdt" ] }, "comments" : [ "Note that, in addition to forming the root of the cellular component ontology, this term is recommended for the annotation of gene products whose cellular component is unknown. When this term is used for annotation, it indicates that no information was available about the cellular component of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this." ], @@ -4261,7 +4280,7 @@ "xrefs" : [ "GOC:go_curators" ] }, "comments" : [ "Note that this term is intended to annotate gene products that are not attached to the cell surface. For gene products from multicellular organisms which are secreted from a cell but retained within the organism (i.e. released into the interstitial fluid or blood), consider the cellular component term 'extracellular space ; GO:0005615'." ], - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_yeast", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "extracellular" @@ -4379,7 +4398,7 @@ "xrefs" : [ "ISBN:0198547684" ] }, "comments" : [ "Note that for multicellular organisms, the extracellular space refers to everything outside a cell, but still within the organism (excluding the extracellular matrix). Gene products from a multi-cellular organism that are secreted from a cell into the interstitial fluid or blood can therefore be annotated to this term." ], - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "intercellular space" @@ -4469,7 +4488,7 @@ "xrefs" : [ "ISBN:0198547684" ] }, "comments" : [ "Chromosomes include parts that are not part of the chromatin. Examples include the kinetochore." ], - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_yeast", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "interphase chromosome" @@ -4517,7 +4536,7 @@ "val" : "The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.", "xrefs" : [ "ISBN:0198547684" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_yeast", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "xrefs" : [ { "val" : "Wikipedia:Cytoplasm" } ], @@ -4538,7 +4557,7 @@ "val" : "An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins.", "xrefs" : [ "ISBN:0198506732" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_yeast", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "free ribosome", @@ -4573,7 +4592,7 @@ "val" : "The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.", "xrefs" : [ "ISBN:0716731363" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_yeast", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "juxtamembrane" @@ -4663,7 +4682,7 @@ "val" : "The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.", "xrefs" : [ "GOC:go_curators" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "protein anabolism" @@ -4802,7 +4821,7 @@ "xrefs" : [ "GOC:dos", "GOC:dph", "GOC:jl", "GOC:mah" ] }, "comments" : [ "Note that this term should not be used for direct annotation. It should be possible to make a more specific annotation to one of the children of this term, for e.g. to transmembrane transport, to microtubule-based transport or to vesicle-mediated transport." ], - "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "single-organism transport" @@ -5600,7 +5619,7 @@ "val" : "Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538).", "xrefs" : [ "GOC:mah", "GOC:mtg_apoptosis", "PMID:25236395" ] }, - "comments" : [ "This term should not be used for direct annotation, it is currently kept in GO as a placeholder for describing cell death phenotypes in uPHENO. When information is provided on a programmed cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'). Unintentional cell death, i.e. cell death caused by injury, ageing, or cell phenotypes observed as a result of a pathological mutation in an essential gene should NOT be annotated using GO terms." ], + "comments" : [ "This term should not be used for direct annotation, it is currently kept in GO as a placeholder for describing cell death phenotypes in uPHENO. When information is provided on a programmed cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'). Unintentional cell death, i.e. cell death caused by injury, ageing, or cell phenotypes observed as a result of a pathological mutation in an essential gene should NOT be annotated using GO terms." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", @@ -6070,7 +6089,7 @@ "xrefs" : [ "GOC:lr", "GOC:mtg_apoptosis" ] }, "comments" : [ "Note that this term should be used to annotate gene products in the organism undergoing the programmed cell death. To annotate genes in another organism whose products modulate programmed cell death in a host organism, consider the term 'modulation by symbiont of host programmed cell death ; GO:0052040'. Also, note that 'programmed cell death ; GO:0012501' should be used to refer to instances of caspase-independent cell death mechanisms, in the absence of further indications on the process taking place. At present, caspase-independent cell death is not yet represented in GO due to the lack of consensus and in-depth research on the topic. 'programmed cell death ; GO:0012501' may also be used to annotate gene products in taxa where apoptosis as defined in GO:0006915 does not occur, such as plants. You may also consider these specific children: GO:0097468 'programmed cell death in response to reactive oxygen species' (with descendants GO:0010421 'hydrogen peroxide-mediated programmed cell death' and GO:0010343 'singlet oxygen-mediated programmed cell death'), and GO:0009626 'plant-type hypersensitive response' and its children." ], - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "regulated cell death" @@ -6560,7 +6579,7 @@ "xrefs" : [ "GOC:mtg_signal", "GOC:mtg_signaling_feb11", "GOC:signaling" ] }, "comments" : [ "Note that a signal is any variable property or parameter that serves to convey information, and may be a physical entity such as a gene product or small molecule, a photon, or a change in state such as movement or voltage change." ], - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pombe", "http://purl.obolibrary.org/obo/go#goslim_yeast", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pombe", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "biological signaling" @@ -6626,7 +6645,7 @@ "val" : "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon.", "xrefs" : [ "GOC:jl", "GOC:mah", "http://www.cogsci.princeton.edu/~wn/" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cell projection organisation" @@ -6941,7 +6960,7 @@ "val" : "A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues.", "xrefs" : [ "GOC:BHF", "GOC:mah", "GOC:rph", "NIF_Subcellular:nlx_subcell_20090513", "PMID:21123617", "PMID:28089324" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "proteinaceous extracellular matrix" @@ -7566,7 +7585,7 @@ "val" : "A prolongation or process extending from a cell, e.g. a flagellum or axon.", "xrefs" : [ "GOC:jl", "http://www.cogsci.princeton.edu/~wn/" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "cell process" @@ -7672,7 +7691,7 @@ "val" : "The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.", "xrefs" : [ "GOC:mah" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_pir" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_pir" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "biopolymer metabolic process", @@ -7688,6 +7707,9 @@ "val" : "multicellular organismal macromolecule metabolic process" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/26424" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0034960" }, { @@ -7743,7 +7765,7 @@ "val" : "Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane.", "xrefs" : [ "GOC:go_curators" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "xrefs" : [ { "val" : "NIF_Subcellular:sao1539965131" }, { @@ -8071,12 +8093,15 @@ "val" : "The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.", "xrefs" : [ "GOC:go_curators", "http://www.metacyc.org" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_pir" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_pir" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "primary metabolism" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/26424" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] @@ -8401,12 +8426,15 @@ "val" : "The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.", "xrefs" : [ "GO_REF:0000021" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_plant" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_plant" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "development of an anatomical structure" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/26424" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] @@ -8434,7 +8462,7 @@ "val" : "Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another.", "xrefs" : [ "GOC:dgh", "GOC:dph", "GOC:isa_complete", "GOC:mlg" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cell locomotion" @@ -8574,7 +8602,7 @@ "xrefs" : [ "GOC:ai", "GOC:bf" ] }, "comments" : [ "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ], - "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_manually_annotate", "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_manually_annotate", "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "physiological response to stimulus" @@ -9196,7 +9224,7 @@ "val" : "The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex.", "xrefs" : [ "GOC:jl" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_pombe", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_pombe", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cellular protein complex assembly" @@ -9362,6 +9390,7 @@ "val" : "The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon.", "xrefs" : [ "GOC:mah" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "organic molecular entity metabolic process" @@ -9373,6 +9402,9 @@ "val" : "organic substance metabolism" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/26424" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "mah" }, { @@ -9464,7 +9496,7 @@ "type" : "CLASS", "meta" : { "definition" : { - "val" : "The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures.", + "val" : "The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures.", "xrefs" : [ "GOC:pdt" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon" ], @@ -9974,6 +10006,9 @@ "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/24200" + }, { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/26424" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "kmv" @@ -11658,47 +11693,6 @@ "val" : "quality" } ] } - }, { - "id" : "http://purl.obolibrary.org/obo/PATO_0000068", - "lbl" : "qualitative", - "type" : "CLASS", - "meta" : { - "comments" : [ "TODO: define this or obsolete it and move children somewhere else." ], - "basicPropertyValues" : [ { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", - "val" : "quality" - } ] - } - }, { - "id" : "http://purl.obolibrary.org/obo/PATO_0000069", - "lbl" : "deviation (from_normal)", - "type" : "CLASS", - "meta" : { - "definition" : { - "val" : "A quality inhering in a bearer by virtue of the whether the bearer differs from normal or average.", - "xrefs" : [ "PATOC:GVG" ] - }, - "subsets" : [ "http://purl.obolibrary.org/obo/pato#attribute_slim" ], - "basicPropertyValues" : [ { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", - "val" : "quality" - } ] - } - }, { - "id" : "http://purl.obolibrary.org/obo/PATO_0000117", - "lbl" : "size", - "type" : "CLASS", - "meta" : { - "definition" : { - "val" : "A morphology quality inhering in a bearer by virtue of the bearer's physical magnitude.", - "xrefs" : [ "WordNet:WordNet" ] - }, - "subsets" : [ "http://purl.obolibrary.org/obo/pato#attribute_slim", "http://purl.obolibrary.org/obo/pato#scalar_slim" ], - "basicPropertyValues" : [ { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", - "val" : "quality" - } ] - } }, { "id" : "http://purl.obolibrary.org/obo/PATO_0000136", "lbl" : "closure", @@ -11787,65 +11781,6 @@ "val" : "quality" } ] } - }, { - "id" : "http://purl.obolibrary.org/obo/PATO_0000461", - "lbl" : "normal", - "type" : "CLASS", - "meta" : { - "definition" : { - "val" : "A quality inhering in a bearer by virtue of the bearer's exhibiting no deviation from normal or average.", - "xrefs" : [ "PATOC:GVG" ] - }, - "subsets" : [ "http://purl.obolibrary.org/obo/pato#abnormal_slim", "http://purl.obolibrary.org/obo/pato#mpath_slim", "http://purl.obolibrary.org/obo/pato#value_slim" ], - "synonyms" : [ { - "pred" : "hasRelatedSynonym", - "val" : "average" - } ], - "basicPropertyValues" : [ { - "pred" : "http://purl.obolibrary.org/obo/RO_0002604", - "val" : "http://purl.obolibrary.org/obo/PATO_0000460" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", - "val" : "quality" - } ] - } - }, { - "id" : "http://purl.obolibrary.org/obo/PATO_0000586", - "lbl" : "increased size", - "type" : "CLASS", - "meta" : { - "definition" : { - "val" : "A size quality which is relatively high.", - "xrefs" : [ "PATOC:GVG" ] - }, - "subsets" : [ "http://purl.obolibrary.org/obo/pato#value_slim" ], - "synonyms" : [ { - "pred" : "hasRelatedSynonym", - "val" : "big" - }, { - "pred" : "hasRelatedSynonym", - "val" : "enlarged" - }, { - "pred" : "hasRelatedSynonym", - "val" : "expanded" - }, { - "pred" : "hasRelatedSynonym", - "val" : "great" - }, { - "pred" : "hasRelatedSynonym", - "val" : "large" - } ], - "basicPropertyValues" : [ { - "pred" : "http://purl.obolibrary.org/obo/RO_0002604", - "val" : "http://purl.obolibrary.org/obo/PATO_0000587" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", - "val" : "PATO:0001202" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", - "val" : "quality" - } ] - } }, { "id" : "http://purl.obolibrary.org/obo/PATO_0000608", "lbl" : "closed", @@ -12613,52 +12548,6 @@ "val" : "quality" } ] } - }, { - "id" : "http://purl.obolibrary.org/obo/PATO_0002300", - "lbl" : "increased quality", - "type" : "CLASS", - "meta" : { - "definition" : { - "val" : "A quality that has a value that is increased compared to normal or average.", - "xrefs" : [ "PATOC:GVG" ] - }, - "basicPropertyValues" : [ { - "pred" : "http://purl.obolibrary.org/obo/RO_0002604", - "val" : "http://purl.obolibrary.org/obo/PATO_0002301" - }, { - "pred" : "http://purl.org/dc/terms/contributor", - "val" : "https://orcid.org/0000-0002-2061-091X" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", - "val" : "2011-06-16T06:39:43Z" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", - "val" : "quality" - } ] - } - }, { - "id" : "http://purl.obolibrary.org/obo/PATO_0002305", - "lbl" : "increased object quality", - "type" : "CLASS", - "meta" : { - "definition" : { - "val" : "A quality of an object that has a value that is increased compared to normal or average.", - "xrefs" : [ "PATOC:GVG" ] - }, - "basicPropertyValues" : [ { - "pred" : "http://purl.obolibrary.org/obo/RO_0002604", - "val" : "http://purl.obolibrary.org/obo/PATO_0002303" - }, { - "pred" : "http://purl.org/dc/terms/contributor", - "val" : "https://orcid.org/0000-0002-2061-091X" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", - "val" : "2011-06-16T06:54:01Z" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", - "val" : "quality" - } ] - } }, { "id" : "http://purl.obolibrary.org/obo/PATO_0002309", "lbl" : "fiber shaped", @@ -12809,6 +12698,28 @@ "val" : "quality" } ] } + }, { + "id" : "http://purl.obolibrary.org/obo/PATO_0040072", + "lbl" : "high nuclear/cytoplasmic ratio", + "type" : "CLASS", + "meta" : { + "definition" : { + "val" : "A quality inhering in a cell by virtue of the cell having a high nuclear/cytoplasmic ratio.", + "xrefs" : [ "Wikipedia:NC_ratio&oldid=931936284", "http://lymerick.net/blood-cells.pdf" ] + }, + "comments" : [ "A high nuclear/cytolasmic ratio is 70% or higher." ], + "synonyms" : [ { + "pred" : "hasExactSynonym", + "val" : "high N:C ratio" + } ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", + "val" : "http://orcid.org/0000-0001-5208-3432" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "quality" + } ] + } }, { "id" : "http://purl.obolibrary.org/obo/PATO_0070006", "lbl" : "cortical bipolar morphology", @@ -15654,6 +15565,9 @@ "val" : "inverse of develops from" }, "subsets" : [ "http://purl.obolibrary.org/obo/RO_0002259" ], + "xrefs" : [ { + "val" : "RO:0002203" + } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000114", "val" : "http://purl.obolibrary.org/obo/IAO_0000125" @@ -15666,6 +15580,12 @@ }, { "pred" : "http://purl.obolibrary.org/obo/IAO_0000117", "val" : "https://orcid.org/0000-0003-1980-3228" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "uberon" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#shorthand", + "val" : "develops_into" } ] } }, { @@ -20008,7 +19928,7 @@ "val" : "eye", "xrefs" : [ "FMA:54448" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "regio orbitalis", "xrefs" : [ "FMA:54448", "FMA:TA" ] @@ -20308,7 +20228,7 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "tunica serosa", "xrefs" : [ "FMA:9581" ] @@ -21125,7 +21045,7 @@ "val" : "zygote", "xrefs" : [ "VHOG:0000745" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "zygotum", "xrefs" : [ "Wikipedia:Zygote" ] @@ -21457,7 +21377,7 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#efo_slim", "http://purl.obolibrary.org/obo/uberon/core#major_organ", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "regio oralis", "xrefs" : [ "BTO:0004698", "FMA:49184", "FMA:TA" ] @@ -21465,7 +21385,7 @@ "pred" : "hasNarrowSynonym", "val" : "adult mouth" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "cavital oralis", "xrefs" : [ "Wikipedia:Mouth" ] @@ -22483,8 +22403,6 @@ "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#common_anatomy", "http://purl.obolibrary.org/obo/uberon/core#upper_level" ], "xrefs" : [ { "val" : "FBbt:00007277" - }, { - "val" : "IDOMAL:0002461" }, { "val" : "VHOG:0001737" } ], @@ -23534,11 +23452,11 @@ "pred" : "hasExactSynonym", "val" : "cranial II" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "nervus opticus" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "nervus opticus [II]", "xrefs" : [ "FMA:50863", "FMA:TA" ] @@ -23932,7 +23850,7 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "chiasma opticum", "xrefs" : [ "Wikipedia:Optic_chiasm" ] @@ -23945,12 +23863,12 @@ "val" : "optic chiasm", "xrefs" : [ "Wikipedia:Optic_chiasm" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "chiasma", "xrefs" : [ "NeuroNames:459" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "chiasma nervorum opticorum", "xrefs" : [ "NeuroNames:459" ] @@ -24560,7 +24478,7 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "systema cardiovasculare", "xrefs" : [ "Wikipedia:Circulatory_system" ] @@ -24569,6 +24487,8 @@ "val" : "AAO:0000959" }, { "val" : "CALOHA:TS-2103" + }, { + "val" : "MESH:D002319" }, { "val" : "VHOG:0001248" }, { @@ -24626,7 +24546,7 @@ "pred" : "hasExactSynonym", "val" : "musculature" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "musculi", "xrefs" : [ "FMA:32558", "FMA:TA" ] @@ -24700,7 +24620,7 @@ "val" : "The nervous system is an organ system containing predominantly neuron and glial cells. In bilaterally symmetrical organism, it is arranged in a network of tree-like structures connected to a central body. The main functions of the nervous system are to regulate and control body functions, and to receive sensory input, process this information, and generate behavior [CUMBO].", "xrefs" : [ "BIRNLEX:844", "ISBN:0-14-051288-8", "ISBN:3110148986", "NLM:nervous+system", "WB:rynl", "Wikipedia:Nervous_system", "ZFIN:curator" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#cumbo", "http://purl.obolibrary.org/obo/uberon/core#efo_slim", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], + "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#cumbo", "http://purl.obolibrary.org/obo/uberon/core#efo_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "neurological system", @@ -24710,7 +24630,7 @@ "val" : "nerve net", "xrefs" : [ "Wikipedia:Nerve_net" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "systema nervosum", "xrefs" : [ "Wikipedia:Nervous_system" ] @@ -24773,6 +24693,9 @@ "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_6040" + }, { + "pred" : "http://purl.obolibrary.org/obo/RO_0002175", + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" }, { "pred" : "http://purl.obolibrary.org/obo/UBPROP_0000001", "val" : "A regulatory system of the body that consists of neurons and neuroglial cells. The nervous system is divided into two parts, the central nervous system (CNS) and the peripheral nervous system (PNS). (Source: BioGlossary, www.Biology-Text.com)[TAO]" @@ -24808,13 +24731,13 @@ "val" : "The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the neural tube derivatives: the brain and spinal cord. In invertebrates it includes central ganglia plus nerve cord.", "xrefs" : [ "GO:0021551", "http://www.frontiersinzoology.com/content/7/1/29", "https://sourceforge.net/p/geneontology/ontology-requests/11422/" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#cumbo", "http://purl.obolibrary.org/obo/uberon/core#efo_slim", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], + "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#cumbo", "http://purl.obolibrary.org/obo/uberon/core#efo_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], "synonyms" : [ { "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003000", "pred" : "hasExactSynonym", "val" : "CNS" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "systema nervosum centrale", "xrefs" : [ "FMA:55675", "FMA:TA" ] @@ -24885,6 +24808,9 @@ "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099" + }, { + "pred" : "http://purl.obolibrary.org/obo/RO_0002175", + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" }, { "pred" : "http://purl.obolibrary.org/obo/UBPROP_0000001", "val" : "Part of the nervous system which includes the brain and spinal cord.[AAO]" @@ -24970,7 +24896,7 @@ "val" : "fascicle", "xrefs" : [ "FBbt:00005101" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "fasciculus" }, { @@ -25023,7 +24949,7 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#efo_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "organa sensuum", "xrefs" : [ "FMA:75259", "FMA:TA" ] @@ -25047,7 +24973,7 @@ "val" : "sensory systems", "xrefs" : [ "TAO:0000282" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "organa sensuum", "xrefs" : [ "Wikipedia:Sensory_system" ] @@ -25182,7 +25108,7 @@ "pred" : "hasRelatedSynonym", "val" : "presumptive central nervous system" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "tubus neuralis", "xrefs" : [ "Wikipedia:Neural_tube" ] @@ -25333,7 +25259,7 @@ "pred" : "hasExactSynonym", "val" : "smooth muscle" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "textus muscularis nonstriatus", "xrefs" : [ "FMA:14070", "FMA:TA" ] @@ -25346,7 +25272,7 @@ "pred" : "hasNarrowSynonym", "val" : "visceral muscle tissue" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "textus muscularis levis; textus muscularis nonstriatus", "xrefs" : [ "Wikipedia:Smooth_muscle_tissue" ] @@ -25653,7 +25579,7 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "facia/facies", "xrefs" : [ "Wikipedia:Face" ] @@ -25763,6 +25689,8 @@ "val" : "FMA:45615" }, { "val" : "MA:0000917" + }, { + "val" : "MESH:D041981" }, { "val" : "NCIT:C34082" }, { @@ -25832,7 +25760,7 @@ "val" : "ciliaris", "xrefs" : [ "Wikipedia:Ciliary_muscle" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "musculus ciliaris", "xrefs" : [ "Wikipedia:Ciliary_muscle" ] @@ -26032,7 +25960,7 @@ "val" : "camera anterior bulbi", "xrefs" : [ "BTO:0002084" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "camera anterior bulbi oculi", "xrefs" : [ "Wikipedia:Anterior_chamber_of_eyeball" ] @@ -26113,7 +26041,7 @@ "val" : "tunica vasculatis oculi", "xrefs" : [ "Wikipedia:Uvea" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "tunica vasculosa bulbi", "xrefs" : [ "Wikipedia:Uvea" ] @@ -26269,7 +26197,7 @@ "pred" : "hasExactSynonym", "val" : "epithelium anterius (cornea)" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "epithelium anterius corneae", "xrefs" : [ "FMA:58263", "FMA:TA" ] @@ -26287,7 +26215,7 @@ "val" : "anterior endothelium of cornea", "xrefs" : [ "BTO:0000287" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "e. anterius corneae", "xrefs" : [ "Wikipedia:Corneal_epithelium" ] @@ -26459,7 +26387,7 @@ "val" : "ciliary bodies", "xrefs" : [ "VHOG:0000102" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "corpus ciliare", "xrefs" : [ "Wikipedia:Ciliary_body" ] @@ -26546,7 +26474,7 @@ "val" : "chorioid", "xrefs" : [ "BTO:0001829" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "choroidea", "xrefs" : [ "Wikipedia:Choroid" ] @@ -26627,7 +26555,7 @@ "pred" : "hasExactSynonym", "val" : "stroma of cornea" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "substantia propria corneae", "xrefs" : [ "FMA:58306", "FMA:TA" ] @@ -26809,7 +26737,7 @@ "pred" : "hasExactSynonym", "val" : "stratum pigmentosum (retina)" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "stratum pigmentosum retinae", "xrefs" : [ "FMA:58627", "FMA:TA" ] @@ -26824,7 +26752,7 @@ "val" : "epithelium, retinal pigment", "xrefs" : [ "BTO:0001177" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "p. pigmentosa retinae", "xrefs" : [ "Wikipedia:Retinal_pigment_epithelium" ] @@ -26839,7 +26767,7 @@ "val" : "retinal pigment layer", "xrefs" : [ "VHOG:0000536" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "stratum pigmentosa retinae", "xrefs" : [ "Wikipedia:Retinal_pigment_epithelium" ] @@ -26922,7 +26850,7 @@ "pred" : "hasExactSynonym", "val" : "stratum segmentorum externorum et internorum (retina)" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "stratum segmentorum externorum et internorum retinae", "xrefs" : [ "FMA:58680", "FMA:TA" ] @@ -27008,7 +26936,7 @@ "pred" : "hasExactSynonym", "val" : "stratum limitans externum (retina)" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "stratum limitans externum retinae", "xrefs" : [ "FMA:58683", "FMA:TA" ] @@ -27080,7 +27008,7 @@ "pred" : "hasExactSynonym", "val" : "stratum nucleare externum (retina)" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "stratum nucleare externum retinae", "xrefs" : [ "FMA:58684", "FMA:TA" ] @@ -27171,7 +27099,7 @@ "pred" : "hasExactSynonym", "val" : "stratum plexiforme externum" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "stratum plexiforme externum retinae", "xrefs" : [ "FMA:58685", "FMA:TA" ] @@ -27259,7 +27187,7 @@ "pred" : "hasExactSynonym", "val" : "stratum nucleare internum" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "stratum nucleare internum retinae", "xrefs" : [ "FMA:58686", "FMA:TA" ] @@ -27366,7 +27294,7 @@ "val" : "retina, ganglion cell layer", "xrefs" : [ "BAMS:Rgcl" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "stratum ganglionicum retinae", "xrefs" : [ "Wikipedia:Ganglion_cell_layer" ] @@ -27453,7 +27381,7 @@ "pred" : "hasExactSynonym", "val" : "stratum neurofibrarum (retina)" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "stratum neurofibrarum retinae", "xrefs" : [ "FMA:58688", "FMA:TA" ] @@ -27474,7 +27402,7 @@ "val" : "optic fiber layers", "xrefs" : [ "TAO:0002212" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "stratum neurofibrum retinae", "xrefs" : [ "Wikipedia:Nerve_fiber_layer" ] @@ -27547,7 +27475,7 @@ "pred" : "hasExactSynonym", "val" : "retina internal limiting lamina" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "stratum limitans internum retinae", "xrefs" : [ "FMA:58689", "FMA:TA" ] @@ -27634,7 +27562,7 @@ "val" : "stratum plexifome internum", "xrefs" : [ "BTO:0003175" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "stratum plexiforme internum retinae", "xrefs" : [ "Wikipedia:Inner_plexiform_layer" ] @@ -27708,7 +27636,7 @@ "val" : "aqueous humour", "xrefs" : [ "EHDAA2:0000139" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "humor aquosus", "xrefs" : [ "FMA:58819", "FMA:TA" ] @@ -27777,7 +27705,7 @@ "pred" : "hasExactSynonym", "val" : "humor vitreous" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "humor vitreus", "xrefs" : [ "FMA:58822", "FMA:TA" ] @@ -27819,6 +27747,8 @@ "val" : "FMA:58822" }, { "val" : "MA:0001286" + }, { + "val" : "MESH:D014822" }, { "val" : "NCIT:C13323" }, { @@ -27891,7 +27821,7 @@ "val" : "camera postrema", "xrefs" : [ "FMA:58848" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "camera postrema bulbi oculi", "xrefs" : [ "FMA:58848", "FMA:TA" ] @@ -27966,7 +27896,7 @@ "pred" : "hasExactSynonym", "val" : "segmentum anterius (bulbus oculi)" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "segmentum anterius bulbi oculi", "xrefs" : [ "Wikipedia:Anterior_segment_of_eyeball" ] @@ -28031,7 +27961,7 @@ "pred" : "hasExactSynonym", "val" : "segmentum posterius (bulbus oculi)" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "segmentum posterius bulbi oculi", "xrefs" : [ "Wikipedia:Posterior_segment_of_eyeball" ] @@ -28082,7 +28012,7 @@ "val" : "conjunctivas", "xrefs" : [ "XAO:0000182" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "tunica conjunctiva", "xrefs" : [ "FMA:TA" ] @@ -28250,7 +28180,7 @@ "val" : "MB", "xrefs" : [ "BIRNLEX:1667", "NIFSTD:NeuroNames_abbrevSource" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "mesencephalon", "xrefs" : [ "Wikipedia:Midbrain" ] @@ -28386,7 +28316,7 @@ "val" : "betweenbrain", "xrefs" : [ "BTO:0000342" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "diencephalon", "xrefs" : [ "Wikipedia:Diencephalon" ] @@ -28516,12 +28446,12 @@ "val" : "medulla", "xrefs" : [ "ABA:MY" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "bulbus", "xrefs" : [ "FMA:62004", "FMA:TA" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "medulla oblonzata", "xrefs" : [ "Wikipedia:Medulla_oblongata" ] @@ -28632,12 +28562,12 @@ "val" : "optic tracts", "xrefs" : [ "ZFA:0000252" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "tractus optici", "xrefs" : [ "NeuroNames:460" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "tractus opticus", "xrefs" : [ "Wikipedia:Optic_tract" ] @@ -28732,7 +28662,7 @@ "val" : "tegmentum", "xrefs" : [ "ISBN:0471888893" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "tegmentum mesencephali", "xrefs" : [ "Wikipedia:Midbrain_tegmentum" ] @@ -28744,7 +28674,7 @@ "val" : "mesencephalic tegmentum", "xrefs" : [ "VHOG:0001367" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "tegmentum mesencephalicum", "xrefs" : [ "NeuroNames:491" ] @@ -28771,6 +28701,8 @@ "val" : "MA:0000212" }, { "val" : "MAT:0000452" + }, { + "val" : "MESH:D013681" }, { "val" : "SCTID:362392007" }, { @@ -28882,7 +28814,7 @@ "val" : "vascular tree organ region", "xrefs" : [ "FMA:50722" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "vas sanguineum", "xrefs" : [ "Wikipedia:Blood_vessel" ] @@ -28984,7 +28916,7 @@ "val" : "endothelium of cornea", "xrefs" : [ "OBOL:automatic" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "epithelium posterius corneae", "xrefs" : [ "Wikipedia:Corneal_endothelium" ] @@ -29099,7 +29031,7 @@ "val" : "neuronal grey matter", "xrefs" : [ "AEO:0001012" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "substantia grisea", "xrefs" : [ "FMA:67242", "FMA:TA" ] @@ -29108,7 +29040,7 @@ "val" : "gray mater", "xrefs" : [ "ZFA:0001681" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "grisea" } ], @@ -29492,6 +29424,8 @@ "val" : "MA:0002986" }, { "val" : "MAT:0000148" + }, { + "val" : "MESH:D013131" }, { "val" : "MIAA:0000148" }, { @@ -29882,7 +29816,7 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "cavitas thoracis", "xrefs" : [ "Wikipedia:Thoracic_cavity" ] @@ -29962,17 +29896,17 @@ "val" : "cerebrocerebellar fissure", "xrefs" : [ "NeuroNames:22" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "fissura cerebro-cerebellaris", "xrefs" : [ "NeuroNames:22" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "fissura cerebrocerebellaris", "xrefs" : [ "NeuroNames:22" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "medulla spinalis", "xrefs" : [ "BTO:0001279", "Wikipedia:Spinal_cord" ] @@ -30089,7 +30023,7 @@ "val" : "brain stem", "xrefs" : [ "ABA:BS" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "truncus encephali", "xrefs" : [ "Wikipedia:Brainstem" ] @@ -30098,27 +30032,27 @@ "val" : "accessory medullary lamina of pallidum", "xrefs" : [ "NeuroNames:236" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "lamella pallidi incompleta", "xrefs" : [ "NeuroNames:236" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "lamina medullaris accessoria", "xrefs" : [ "NeuroNames:236" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "lamina medullaris incompleta pallidi", "xrefs" : [ "NeuroNames:236" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "lamina pallidi incompleta", "xrefs" : [ "NeuroNames:236" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "truncus encephalicus", "xrefs" : [ "BTO:0000146" ] @@ -30222,7 +30156,7 @@ "val" : "CNS white matter", "xrefs" : [ "TAO:0002143" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "substantia alba", "xrefs" : [ "Wikipedia:White_matter" ] @@ -30404,7 +30338,7 @@ "val" : "notocord", "xrefs" : [ "ZFA:0000135" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "notochorda", "xrefs" : [ "Wikipedia:Notochord" ] @@ -30517,7 +30451,7 @@ "pred" : "hasRelatedSynonym", "val" : "somitic mesoderm" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "somitus", "xrefs" : [ "Wikipedia:Somite" ] @@ -30613,7 +30547,7 @@ "val" : "NC", "xrefs" : [ "XAO:0000048" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "crista neuralis", "xrefs" : [ "Wikipedia:Neural_crest" ] @@ -30707,7 +30641,7 @@ "pred" : "hasExactSynonym", "val" : "neuroectoderm" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "epithelium tubi neuralis; neuroectoderma", "xrefs" : [ "Wikipedia:Neuroectoderm" ] @@ -31037,7 +30971,7 @@ "val" : "epithelium pigmentosum (iris)", "xrefs" : [ "FMA:58517" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "epithelium pigmentosum iridis", "xrefs" : [ "FMA:58517", "FMA:TA" ] @@ -31095,7 +31029,7 @@ "val" : "ectoblast", "xrefs" : [ "MP:0003886" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "epiblastus", "xrefs" : [ "Wikipedia:Epiblast" ] @@ -31733,7 +31667,7 @@ "val" : "lens placodes", "xrefs" : [ "ZFA:0000122" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "placoda lentis", "xrefs" : [ "Wikipedia:Lens_placode" ] @@ -31793,7 +31727,7 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "lamina neuralis", "xrefs" : [ "Wikipedia:Neural_plate" ] @@ -31895,7 +31829,7 @@ "val" : "somitic mesoderm", "xrefs" : [ "ISBN:9780878932504" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "mesoderma paraxiale", "xrefs" : [ "Wikipedia:Paraxial_mesoderm" ] @@ -31998,7 +31932,7 @@ "val" : "lateral plate mesenchyme", "xrefs" : [ "EHDAA2:0000919" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "mesoderma laminae lateralis", "xrefs" : [ "Wikipedia:Lateral_plate_mesoderm" ] @@ -32119,7 +32053,7 @@ "val" : "sclerotomes", "xrefs" : [ "TAO:0001080" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "sclerotomus", "xrefs" : [ "Wikipedia:Sclerotome" ] @@ -32184,7 +32118,7 @@ "val" : "optic stalks", "xrefs" : [ "ZFA:0000137" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "pedunculus opticus", "xrefs" : [ "Wikipedia:Optic_stalk" ] @@ -32254,7 +32188,7 @@ "pred" : "hasExactSynonym", "val" : "head NCC population" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "crista neuralis cranialis", "xrefs" : [ "Wikipedia:Cranial_neural_crest" ] @@ -32368,7 +32302,7 @@ "pred" : "hasExactSynonym", "val" : "portion of mesenchyme tissue" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "mesenchyma", "xrefs" : [ "Wikipedia:Mesenchyme" ] @@ -32991,7 +32925,7 @@ "val" : "stratum nervosum (retina)", "xrefs" : [ "FMA:58628" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "stratum nervosum retinae", "xrefs" : [ "FMA:58628", "FMA:TA" ] @@ -33803,7 +33737,7 @@ "val" : "lamina limitans posterior", "xrefs" : [ "FMA:58309" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "lamina limitans posterior corneae", "xrefs" : [ "FMA:58309", "FMA:TA" ] @@ -33893,12 +33827,12 @@ "val" : "lamina limitans anterior (cornea)", "xrefs" : [ "FMA:58273" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "lamina limitans anterior corneae", "xrefs" : [ "FMA:58273", "FMA:TA" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#DUBIOUS", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003002", "pred" : "hasRelatedSynonym", "val" : "Reichert's membrane", "xrefs" : [ "http://sourceforge.net/tracker/?func=detail&aid=2956371&group_id=76834&atid=974957" ] @@ -34100,7 +34034,7 @@ "val" : "An endothelium that lines the blood vasculature. Other endothelia may line lymph vessels, the heart.", "xrefs" : [ "https://orcid.org/0000-0002-6601-2165" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], + "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], "xrefs" : [ { "val" : "BTO:0000766" }, { @@ -34119,6 +34053,9 @@ "val" : "ZFA:0005257" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/RO_0002175", + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "uberon" } ] @@ -35505,7 +35442,7 @@ "val" : "basement membrane of connective tissue", "xrefs" : [ "FMA:63872" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "membrana basalis", "xrefs" : [ "Wikipedia:Basement_membrane" ] @@ -35626,7 +35563,7 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "skeleton axiale", "xrefs" : [ "Wikipedia:Axial_skeleton" ] @@ -35684,7 +35621,7 @@ "val" : "nerve fibre", "xrefs" : [ "FMA:5914" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "neurofibra", "xrefs" : [ "FMA:5914", "FMA:TA" ] @@ -35698,7 +35635,7 @@ "val" : "nerve fibers", "xrefs" : [ "BAMS:nfi" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "neurofibra", "xrefs" : [ "Wikipedia:Nerve_fiber" ] @@ -37785,7 +37722,7 @@ "val" : "ciliary processes set", "xrefs" : [ "FMA:76551" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "processus ciliares", "xrefs" : [ "FMA:TA" ] @@ -37798,7 +37735,7 @@ "val" : "ciliary process", "xrefs" : [ "Wikipedia:Ciliary_processes" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "processus ciliares", "xrefs" : [ "Wikipedia:Ciliary_processes" ] @@ -37948,7 +37885,7 @@ "val" : "A subdivision of an anatomical system.", "xrefs" : [ "http://orcid.org/0000-0002-6601-2165" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#common_anatomy", "http://purl.obolibrary.org/obo/uberon/core#upper_level" ], + "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#common_anatomy", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#upper_level" ], "xrefs" : [ { "val" : "FBbt:00007330" }, { @@ -37965,6 +37902,9 @@ }, { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_4751" + }, { + "pred" : "http://purl.obolibrary.org/obo/RO_0002175", + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "uberon" @@ -38142,12 +38082,12 @@ "xrefs" : [ "FMA:19783" ] }, "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "textus connectivus collagenosus laxus", "xrefs" : [ "FMA:19783", "FMA:TA" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "textus connectivus laxus", "xrefs" : [ "FMA:19783", "FMA:TA" ] @@ -38413,7 +38353,7 @@ "val" : "The region of the organism associated with the visceral organs.", "xrefs" : [ "AEO:0000103" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#non_informative" ], + "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#non_informative" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "body", @@ -38433,9 +38373,6 @@ "val" : "FMA:231424" } ], "basicPropertyValues" : [ { - "pred" : "http://purl.obolibrary.org/obo/RO_0002175", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" - }, { "pred" : "http://purl.obolibrary.org/obo/UBPROP_0000001", "val" : "Cardinal body part, which consists of a maximal set of diverse subclasses of organ and organ part spatially associated with the vertebral column and ribcage. Examples: There is only one body proper[FMA:231424]." }, { @@ -39012,7 +38949,7 @@ "xrefs" : [ "HPO:pr", "UBERON:cjm", "http://medical-dictionary.thefreedictionary.com/ocular+adnexa", "https://github.com/obophenotype/uberon/issues/1132" ] }, "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "adnexa oculi", "xrefs" : [ "http://medical-dictionary.thefreedictionary.com/ocular+adnexa" ] @@ -39047,7 +38984,7 @@ "val" : "set of accessory visual structures", "xrefs" : [ "FMA:76554" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "structurae oculi accessoriae", "xrefs" : [ "Wikipedia:Accessory_visual_structures" ] @@ -39195,8 +39132,10 @@ "val" : "OBSOLETE A relation between a cell and molecule or complex such that every instance of the cell has a high number of instances of that molecule expressed on the cell surface. For the formal definition, see Masci et al (PMID:19243617).", "xrefs" : [ "PMID:19243617" ] }, - "comments" : [ "Replaced with RO:0015015, see https://github.com/obophenotype/cell-ontology/issues/1481" ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/obophenotype/cell-ontology/issues/1481" + }, { "pred" : "http://purl.obolibrary.org/obo/IAO_0100001", "val" : "http://purl.obolibrary.org/obo/RO_0015015" } ], @@ -39211,8 +39150,10 @@ "val" : "OBSOLETE A relation between a cell and molecule or complex such that every instance of the cell has a low number of instances of that molecule expressed on the cell surface. For the formal definition, see Masci et al (PMID:19243617).", "xrefs" : [ "PMID:19243617" ] }, - "comments" : [ "Replaced with RO:0015016, see https://github.com/obophenotype/cell-ontology/issues/1481" ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/obophenotype/cell-ontology/issues/1481" + }, { "pred" : "http://purl.obolibrary.org/obo/IAO_0100001", "val" : "http://purl.obolibrary.org/obo/RO_0015016" } ], @@ -39442,13 +39383,12 @@ "lbl" : "transitively anteriorly connected to", "type" : "PROPERTY", "meta" : { - "definition" : { - "val" : ".", - "xrefs" : [ "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" ] - }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "uberon" + }, { + "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", + "val" : "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" } ] } }, { @@ -39456,13 +39396,12 @@ "lbl" : "transitively distally connected to", "type" : "PROPERTY", "meta" : { - "definition" : { - "val" : ".", - "xrefs" : [ "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" ] - }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "uberon" + }, { + "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", + "val" : "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" } ] } }, { @@ -39470,13 +39409,12 @@ "lbl" : "transitively proximally connected to", "type" : "PROPERTY", "meta" : { - "definition" : { - "val" : ".", - "xrefs" : [ "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" ] - }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "uberon" + }, { + "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", + "val" : "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" } ] } }, { @@ -40544,10 +40482,6 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0000547", "pred" : "http://purl.obolibrary.org/obo/BFO_0000051", "obj" : "http://purl.obolibrary.org/obo/CL_0017503" - }, { - "sub" : "http://purl.obolibrary.org/obo/CL_0000547", - "pred" : "http://purl.obolibrary.org/obo/BFO_0000051", - "obj" : "http://purl.obolibrary.org/obo/CL_0017505" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000547", "pred" : "http://purl.obolibrary.org/obo/BFO_0000051", @@ -40596,6 +40530,10 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0000547", "pred" : "http://purl.obolibrary.org/obo/CL_4030046", "obj" : "http://purl.obolibrary.org/obo/PR_000002978" + }, { + "sub" : "http://purl.obolibrary.org/obo/CL_0000547", + "pred" : "http://purl.obolibrary.org/obo/RO_0000053", + "obj" : "http://purl.obolibrary.org/obo/PATO_0040072" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000547", "pred" : "http://purl.obolibrary.org/obo/RO_0002104", @@ -41554,14 +41492,6 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0017504", "pred" : "http://purl.obolibrary.org/obo/RO_0000053", "obj" : "http://purl.obolibrary.org/obo/PATO_0070047" - }, { - "sub" : "http://purl.obolibrary.org/obo/CL_0017505", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/GO_0005634" - }, { - "sub" : "http://purl.obolibrary.org/obo/CL_0017505", - "pred" : "http://purl.obolibrary.org/obo/RO_0000053", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000586" }, { "sub" : "http://purl.obolibrary.org/obo/CL_1000432", "pred" : "is_a", @@ -43872,18 +43802,6 @@ "sub" : "http://purl.obolibrary.org/obo/PATO_0000052", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/PATO_0000051" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0000068", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000001" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0000069", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000068" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0000117", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000051" }, { "sub" : "http://purl.obolibrary.org/obo/PATO_0000136", "pred" : "is_a", @@ -43900,18 +43818,6 @@ "sub" : "http://purl.obolibrary.org/obo/PATO_0000411", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/PATO_0000947" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0000461", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000068" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0000586", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000117" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0000586", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0002305" }, { "sub" : "http://purl.obolibrary.org/obo/PATO_0000608", "pred" : "is_a", @@ -44076,22 +43982,6 @@ "sub" : "http://purl.obolibrary.org/obo/PATO_0002299", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/PATO_0002078" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0002300", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000069" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0002300", - "pred" : "http://purl.obolibrary.org/obo/RO_0015007", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000461" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0002305", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0001241" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0002305", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0002300" }, { "sub" : "http://purl.obolibrary.org/obo/PATO_0002309", "pred" : "is_a", @@ -44120,6 +44010,10 @@ "sub" : "http://purl.obolibrary.org/obo/PATO_0015006", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/PATO_0000141" + }, { + "sub" : "http://purl.obolibrary.org/obo/PATO_0040072", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/PATO_0001396" }, { "sub" : "http://purl.obolibrary.org/obo/PATO_0070006", "pred" : "is_a", @@ -52679,9 +52573,6 @@ "restrictions" : [ { "propertyId" : "http://purl.obolibrary.org/obo/BFO_0000051", "fillerId" : "http://purl.obolibrary.org/obo/CL_0017503" - }, { - "propertyId" : "http://purl.obolibrary.org/obo/BFO_0000051", - "fillerId" : "http://purl.obolibrary.org/obo/CL_0017505" }, { "propertyId" : "http://purl.obolibrary.org/obo/BFO_0000051", "fillerId" : "http://purl.obolibrary.org/obo/GO_0005730" @@ -52721,6 +52612,9 @@ }, { "propertyId" : "http://purl.obolibrary.org/obo/RO_0000053", "fillerId" : "http://purl.obolibrary.org/obo/PATO_0002505" + }, { + "propertyId" : "http://purl.obolibrary.org/obo/RO_0000053", + "fillerId" : "http://purl.obolibrary.org/obo/PATO_0040072" }, { "propertyId" : "http://purl.obolibrary.org/obo/RO_0002104", "fillerId" : "http://purl.obolibrary.org/obo/PR_000001945" @@ -53175,13 +53069,6 @@ "propertyId" : "http://purl.obolibrary.org/obo/RO_0000053", "fillerId" : "http://purl.obolibrary.org/obo/PATO_0070047" } ] - }, { - "definedClassId" : "http://purl.obolibrary.org/obo/CL_0017505", - "genusIds" : [ "http://purl.obolibrary.org/obo/GO_0005634" ], - "restrictions" : [ { - "propertyId" : "http://purl.obolibrary.org/obo/RO_0000053", - "fillerId" : "http://purl.obolibrary.org/obo/PATO_0000586" - } ] }, { "definedClassId" : "http://purl.obolibrary.org/obo/CL_1000432", "genusIds" : [ "http://purl.obolibrary.org/obo/CL_0000066" ], @@ -53950,27 +53837,6 @@ "propertyId" : "http://purl.obolibrary.org/obo/BFO_0000050", "fillerId" : "http://purl.obolibrary.org/obo/GO_0005576" } ] - }, { - "definedClassId" : "http://purl.obolibrary.org/obo/PATO_0000586", - "genusIds" : [ "http://purl.obolibrary.org/obo/PATO_0000117" ], - "restrictions" : [ { - "propertyId" : "http://purl.obolibrary.org/obo/RO_0015007", - "fillerId" : "http://purl.obolibrary.org/obo/PATO_0000461" - } ] - }, { - "definedClassId" : "http://purl.obolibrary.org/obo/PATO_0002300", - "genusIds" : [ "http://purl.obolibrary.org/obo/PATO_0000001" ], - "restrictions" : [ { - "propertyId" : "http://purl.obolibrary.org/obo/RO_0015007", - "fillerId" : "http://purl.obolibrary.org/obo/PATO_0000461" - } ] - }, { - "definedClassId" : "http://purl.obolibrary.org/obo/PATO_0002305", - "genusIds" : [ "http://purl.obolibrary.org/obo/PATO_0001241" ], - "restrictions" : [ { - "propertyId" : "http://purl.obolibrary.org/obo/RO_0015007", - "fillerId" : "http://purl.obolibrary.org/obo/PATO_0000461" - } ] }, { "definedClassId" : "http://purl.obolibrary.org/obo/PR_000029032", "genusIds" : [ "http://purl.obolibrary.org/obo/PR_000000001" ], diff --git a/src/ontology/subsets/eye_upper_slim.obo b/src/ontology/subsets/eye_upper_slim.obo index 700f7144d..998c256f5 100644 --- a/src/ontology/subsets/eye_upper_slim.obo +++ b/src/ontology/subsets/eye_upper_slim.obo @@ -1,5 +1,5 @@ format-version: 1.2 -data-version: cl/releases/2024-01-04/subsets/eye_upper_slim.owl +data-version: cl/releases/2024-02-13/subsets/eye_upper_slim.owl subsetdef: abnormal_slim "" subsetdef: added_for_HCA "" subsetdef: attribute_slim "" @@ -31,6 +31,7 @@ subsetdef: goslim_mouse "" subsetdef: goslim_pir "" subsetdef: goslim_plant "" subsetdef: goslim_pombe "" +subsetdef: goslim_prokaryote "" subsetdef: goslim_synapse "" subsetdef: goslim_yeast "" subsetdef: grouping_class "" @@ -49,7 +50,6 @@ subsetdef: non_informative "" subsetdef: organ_slim "" subsetdef: pheno_slim "" subsetdef: phenotype_rcn "" -subsetdef: prokaryote_subset "" subsetdef: ro-eco "" subsetdef: RO:0002259 "" subsetdef: scalar_slim "" @@ -62,7 +62,6 @@ subsetdef: vertebrate_core "" synonymtypedef: blast_name "" synonymtypedef: COMPARATIVE_PREFERRED "" synonymtypedef: DEPRECATED "" -synonymtypedef: DUBIOUS "" synonymtypedef: equivalent_name "" synonymtypedef: genbank_common_name "" synonymtypedef: Gene-based "" @@ -71,13 +70,14 @@ synonymtypedef: HUMAN_PREFERRED "" synonymtypedef: HUMAN_PREFERRED "preferred term when talking about an instance of this class in Homo sapiens" synonymtypedef: in_part "" synonymtypedef: INCONSISTENT "" -synonymtypedef: LATIN "" synonymtypedef: LATIN "latin term" synonymtypedef: MISSPELLING "a mis-spelling that is in common use and thus recorded" synonymtypedef: NON_MAMMAL "" synonymtypedef: OMO:0003000 "abbreviation" +synonymtypedef: OMO:0003002 "" synonymtypedef: OMO:0003003 "" synonymtypedef: OMO:0003004 "plural form" +synonymtypedef: OMO:0003011 "" synonymtypedef: PENDING_REVIEW "" synonymtypedef: PLURAL "plural term" synonymtypedef: PRO-short-label "" @@ -88,7 +88,7 @@ synonymtypedef: synonym "" synonymtypedef: SYSTEMATIC "" synonymtypedef: systematic_synonym "" ontology: cl/subsets/eye_upper_slim -property_value: owl:versionInfo "2024-01-04" xsd:string +property_value: owl:versionInfo "2024-02-13" xsd:string [Term] id: BFO:0000002 @@ -144,6 +144,7 @@ id: CL:0000000 name: cell def: "A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane." [CARO:mah] comment: The definition of cell is intended to represent all cells, and thus a cell is defined as a material entity and not an anatomical structure, which implies that it is part of an organism (or the entirety of one). +subset: cellxgene_subset subset: ubprop:upper_level xref: CALOHA:TS-2035 xref: FBbt:00007002 @@ -172,6 +173,7 @@ relationship: develops_from CL:0000008 ! migratory cranial neural crest cell [Term] id: CL:0000006 name: neuronal receptor cell +subset: cellxgene_subset synonym: "neuronal receptor cell (sensu Animalia)" EXACT [] is_a: CL:0000101 ! sensory neuron is_a: CL:0000197 ! sensory receptor cell @@ -194,6 +196,7 @@ is_a: CL:0000333 ! migratory neural crest cell [Term] id: CL:0000030 name: glioblast +subset: cellxgene_subset is_a: CL:0000055 ! non-terminally differentiated cell relationship: develops_from CL:0000133 ! neurectodermal cell @@ -201,6 +204,7 @@ relationship: develops_from CL:0000133 ! neurectodermal cell id: CL:0000031 name: neuroblast (sensu Vertebrata) def: "A cell that will develop into a neuron often after a migration phase." [GOC:NV, http://en.wikipedia.org/wiki/Neuroblast] +subset: cellxgene_subset synonym: "neuroblast" EXACT [] xref: BTO:0000930 xref: FMA:70563 @@ -213,6 +217,7 @@ id: CL:0000034 name: stem cell def: "A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells." [GOC:tfm, MESH:D013234] comment: This term applies to metazoan. For plant stem cells, consider using PO:0004011 ‘initial cell’ or its parent PO:0004010 ‘meristematic cell’. +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "animal stem cell" EXACT [] @@ -231,6 +236,7 @@ name: hematopoietic stem cell def: "A stem cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system. Hematopoietic stem cells lack cell markers of effector cells (lin-negative). Lin-negative is defined by lacking one or more of the following cell surface markers: CD2, CD3 epsilon, CD4, CD5 ,CD8 alpha chain, CD11b, CD14, CD19, CD20, CD56, ly6G, ter119." [GOC:add, GOC:dsd, GOC:tfm, http://en.wikipedia.org/wiki/Hematopoietic_stem_cell, PMID:19022770] comment: Markers differ between species, and two sets of markers have been described for mice. HSCs are reportedly CD34-positive, CD45-positive, CD48-negative, CD150-positive, CD133-positive, and CD244-negative. subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "blood forming stem cell" EXACT [] synonym: "colony forming unit hematopoietic" RELATED [] @@ -280,6 +286,7 @@ id: CL:0000038 name: erythroid progenitor cell def: "A progenitor cell committed to the erythroid lineage." [GOC:add, ISBN:0721601464] subset: blood_and_immune_upper_slim +subset: cellxgene_subset synonym: "BFU-E" RELATED OMO:0003000 [] synonym: "blast forming unit erythroid" RELATED [] synonym: "burst forming unit erythroid" RELATED [] @@ -311,6 +318,7 @@ id: CL:0000049 name: common myeloid progenitor def: "A progenitor cell committed to myeloid lineage, including the megakaryocyte and erythroid lineages." [GOC:add, ISBN:0878932437, MESH:D023461] comment: This cell type is intended to be compatible with any vertebrate common myeloid progenitor. For mammalian CMP known to be CD34-positive, please use the term 'common myeloid progenitor, CD34-positive' (CL_0001059). +subset: cellxgene_subset subset: human_reference_atlas synonym: "CFU-GEMM" RELATED OMO:0003000 [ISBN:0878932437] synonym: "CFU-S" RELATED OMO:0003000 [ISBN:0878932437] @@ -330,6 +338,7 @@ id: CL:0000050 name: megakaryocyte-erythroid progenitor cell def: "A progenitor cell committed to the megakaryocyte and erythroid lineages." [GOC:add, GOC:dsd, GOC:tfm, http://en.wikipedia.org/wiki/Megakaryocyte-erythroid_progenitor_cell, MESH:D055015, PMID:16647566] comment: MEPs are reportedly CD19-negative, CD34-negative, CD45RA-negative, CD110-positive, CD117-positive, and SCA1-negative and reportedly express the transcription factors GATA-1 and NF-E2. +subset: cellxgene_subset subset: human_reference_atlas synonym: "CFU-EM" EXACT [] synonym: "CFU-MegE" EXACT [] @@ -362,6 +371,7 @@ id: CL:0000055 name: non-terminally differentiated cell def: "A precursor cell with a limited number of potential fates." [SANBI:mhl] comment: define using PATO mulit-potent or oligopotent? +subset: cellxgene_subset synonym: "blast cell" EXACT [] xref: BTO:0000125 xref: FMA:84782 @@ -383,6 +393,7 @@ id: CL:0000057 name: fibroblast def: "A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped." [http://en.wikipedia.org/wiki/Fibroblast, ISBN:0517223651, MESH:D005347] comment: These cells may be vimentin-positive, fibronectin-positive, fsp1-positive, MMP-1-positive, collagen I-positive, collagen III-positive, and alpha-SMA-negative. +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas xref: BTO:0000452 @@ -398,6 +409,7 @@ relationship: present_in_taxon NCBITaxon:9606 id: CL:0000066 name: epithelial cell def: "A cell that is usually found in a two-dimensional sheet with a free surface. The cell has a cytoskeleton that allows for tight cell to cell contact and for cell polarity where apical part is directed towards the lumen and the basal part to the basal lamina." [FB:ma, GOC:tfm, MESH:D004847] +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "epitheliocyte" EXACT [] @@ -416,6 +428,7 @@ property_value: depiction "https://www.swissbiopics.org/api/image/Epithelial_cel id: CL:0000071 name: blood vessel endothelial cell def: "An endothelial cell that lines the vasculature." [GOC:tfm] +subset: cellxgene_subset subset: human_reference_atlas synonym: "cuboidal endothelial cell of vascular tree" EXACT [] is_a: CL:0000076 {is_inferred="true"} ! squamous epithelial cell @@ -430,6 +443,7 @@ relationship: present_in_taxon NCBITaxon:9606 id: CL:0000075 name: columnar/cuboidal epithelial cell def: "A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube." [GO:0002065, https://orcid.org/0000-0001-5208-3432] +subset: cellxgene_subset subset: human_reference_atlas is_a: CL:0000066 ! epithelial cell relationship: present_in_taxon NCBITaxon:9606 @@ -437,6 +451,7 @@ relationship: present_in_taxon NCBITaxon:9606 [Term] id: CL:0000076 name: squamous epithelial cell +subset: cellxgene_subset xref: CALOHA:TS-1249 is_a: CL:0000066 ! epithelial cell @@ -444,6 +459,7 @@ is_a: CL:0000066 ! epithelial cell id: CL:0000077 name: mesothelial cell def: "A flattened epithelial cell of mesenchymal origin that lines the serous cavity." [GOC:tfm, ISBN:0721662544] +subset: cellxgene_subset subset: human_reference_atlas synonym: "mesotheliocyte" EXACT [] xref: FMA:66773 @@ -456,6 +472,7 @@ relationship: present_in_taxon NCBITaxon:9606 id: CL:0000081 name: blood cell def: "A cell found predominately in the blood." [GOC:add, GOC:tfm] +subset: cellxgene_subset subset: general_cell_types_upper_slim xref: FMA:62844 xref: MESH:D001773 @@ -467,6 +484,7 @@ relationship: capable_of GO:0008015 ! blood circulation [Term] id: CL:0000095 name: neuron associated cell +subset: cellxgene_subset is_a: CL:0002319 ! neural cell relationship: develops_from CL:0000133 ! neurectodermal cell @@ -474,6 +492,7 @@ relationship: develops_from CL:0000133 ! neurectodermal cell id: CL:0000099 name: interneuron def: "Most generally any neuron which is not motor or sensory. Interneurons may also refer to neurons whose axons remain within a particular brain region as contrasted with projection neurons which have axons projecting to other brain regions." [GOC:tfm, MESH:D007395] +subset: cellxgene_subset subset: human_reference_atlas xref: BTO:0003811 xref: FBbt:00005125 @@ -501,6 +520,7 @@ id: CL:0000103 name: bipolar neuron def: "A type of interneuron that has two neurites, usually an axon and a dendrite, extending from opposite poles of an ovoid cell body." [GOC:tfm, ISBN:0444009442] subset: BDS_subset +subset: cellxgene_subset xref: FMA:67282 is_a: CL:0000099 ! interneuron intersection_of: CL:0000099 ! interneuron @@ -512,6 +532,7 @@ id: CL:0000115 name: endothelial cell def: "An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal. In mammals, endothelial cell has vimentin filaments and is derived from the mesoderm." [GOC:tfm, http://en.wikipedia.org/wiki/Endothelial_cell, https://sourceforge.net/tracker/?func=detail&atid=440764&aid=3364936&group_id=36855, MESH:D042783, PMID:21275341] comment: From FMA: 9.07.2001: Endothelial cell has always been classified as a kind of epithelial cell, specifically a squamous cell but that is not true. First, endothelial cell can either be squamous or cuboidal (e.g. high-endothelial cell) and secondly, it has different embryological derivation (mesodermal) than a true epithelial cell (ectodermal and endodermal). The basis for present classification is the fact that it comprises the outermost layer or lining of anatomical structures (location-based) but a better structural basis for the differentia is the cytoskeleton of the cell. Endothelial cell has vimentin filaments while an epithelial cell has keratin filaments. [Onard]. +subset: cellxgene_subset subset: human_reference_atlas synonym: "endotheliocyte" EXACT [] xref: BTO:0001176 @@ -531,6 +552,7 @@ relationship: part_of UBERON:0001017 ! central nervous system [Term] id: CL:0000123 name: neuron associated cell (sensu Vertebrata) +subset: cellxgene_subset is_a: CL:0000095 ! neuron associated cell is_a: CL:0000255 ! eukaryotic cell relationship: develops_from CL:0000333 ! migratory neural crest cell @@ -541,6 +563,7 @@ id: CL:0000125 name: glial cell def: "A non-neuronal cell of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu. Guide neuronal migration during development, and exchange metabolites with neurons." [MESH:D009457] comment: Not all glial cells develop from glioblasts, with microglia developing from the mesoderm instead. See https://github.com/obophenotype/cell-ontology/issues/1571 +subset: cellxgene_subset subset: general_cell_types_upper_slim synonym: "neuroglia" RELATED [] synonym: "neuroglial cell" EXACT [] @@ -554,6 +577,7 @@ is_a: CL:0000095 ! neuron associated cell id: CL:0000126 name: macroglial cell def: "A neuroglial cell of ectodermal origin, i.e., the astrocytes and oligodendrocytes considered together." [GOC:tfm, ISBN:0721662544] +subset: cellxgene_subset synonym: "macroglia" RELATED OMO:0003004 [doi:10.1152/physrev.2001.81.2.871] synonym: "macrogliocyte" EXACT [] xref: BTO:0000771 @@ -567,6 +591,7 @@ id: CL:0000127 name: astrocyte def: "A class of large neuroglial (macroglial) cells in the central nervous system - the largest and most numerous neuroglial cells in the brain and spinal cord. Astrocytes (from 'star' cells) are irregularly shaped with many long processes, including those with 'end feet' which form the glial (limiting) membrane and directly and indirectly contribute to the blood-brain barrier. They regulate the extracellular ionic and chemical environment, and 'reactive astrocytes' (along with microglia) respond to injury." [GOC:dsd, GOC:tfm, http://en.wikipedia.org/wiki/Astrocyte, MESH:D001253, PMID:11746784, PMID:12162730, PMID:12898703, PMID:20942978] comment: Astrocytes are reportedly CD68-negative, CD121a-positive, CD184-positive, CD192-positive, CRF-positive, EGFR-positive, GFAP-positive, GLUT1-positive, MBP-negative, and NGFR-positive. +subset: cellxgene_subset subset: human_reference_atlas synonym: "astrocytic glia" EXACT [] xref: BTO:0000099 @@ -579,6 +604,7 @@ relationship: present_in_taxon NCBITaxon:9606 id: CL:0000132 name: corneal endothelial cell def: "An hexagonal, flattened, mitochondria-rich endothelial cell that forms a monolayer on the posterior surface of the cornea (the corneal endothelium). Corneal endothelial cells are derived from the neural crest and are responsible for keeping the cornea transparent by maintaining the tissue in a semi-dry state through the action of their ionic pumps and tight junction barrier." [GOC:tfm, PMID:21976958, PMID:23284695, PMID:34741068, PMID:36769303] +subset: cellxgene_subset subset: eye_upper_slim subset: human_reference_atlas xref: CALOHA:TS-0172 @@ -601,6 +627,7 @@ id: CL:0000134 name: mesenchymal stem cell def: "A connective tissue cell that normally gives rise to other cells that are organized as three-dimensional masses. In humans, this cell type is CD73-positive, CD90-positive, CD105-positive, CD45-negative, CD34-negative, and MHCII-negative. They may further differentiate into osteoblasts, adipocytes, myocytes, neurons, or chondroblasts in vitro. Originally described as residing in the bone marrow, this cell type is now known to reside in many, if not all, adult organs." [FB:ma, GOC:dsd, http://en.wikipedia.org/wiki/Mesenchymal_stem_cell, http://www.copewithcytokines.de/cope.cgi?key=mesenchymal%20stem%20cells, PMCID:PMC2613570, PMID:10102814, PMID:16923606, PMID:17986482, PMID:19960544] comment: Many but not all mesenchymal cells derive from the mesoderm. MSCs are reportedly CD3-negative, CD4-negative, CD5-negative, CD8-negative, CD11a-negative, CD11b-negative, CD14-negative, CD19-negative, CD29-positive, CD31-negative, CD34-negative, CD38-negative, CD40-negative, CD44-positive, CD45-negative, CD49-positive, CD54-positive, CD66b-negative, CD79a-negative, CD80-negative, CD102-positive, CD106-positive, CD117-positive, CD121a-positive, CD121b-positive, CD123-positive, CD124-positive, CD133-negative, CD146-positive, CD166-positive, CD271-positive, B220-negative, Gr1-negative, MHCI-positive, MHCII-negative, SSEA4-negative, sca1-positive, Ter119-negative, and glycophorin A-negative. Cultured MSCs are capable of producing stem cell factor, IL7, IL8, IL11, TGF-beta, cofilin, galectin-1, laminin-receptor 1, cyclophilin A, and MMP-2. +subset: cellxgene_subset synonym: "BMSC" RELATED OMO:0003000 [] synonym: "bone marrow stromal cells" NARROW [] synonym: "CFU-F" RELATED OMO:0003000 [] @@ -633,6 +660,7 @@ is_a: CL:0000325 ! stuff accumulating cell id: CL:0000148 name: melanocyte def: "A pigment cell derived from the neural crest. Contains melanin-filled pigment granules, which gives a brown to black appearance." [SANBI:mhl] +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "melanophore" NARROW [] @@ -659,6 +687,7 @@ is_a: CL:0000147 ! pigment cell id: CL:0000151 name: secretory cell def: "A cell that specializes in controlled release of one or more substances." [GOC:tfm, ISBN:0721662544] +subset: cellxgene_subset xref: BTO:0003659 xref: FMA:86916 is_a: CL:0000000 ! cell @@ -670,12 +699,14 @@ relationship: capable_of GO:0032940 ! secretion by cell id: CL:0000183 name: contractile cell def: "A cell whose primary function is to shorten." [FB:ma] +subset: cellxgene_subset is_a: CL:0000000 ! cell [Term] id: CL:0000187 name: muscle cell def: "A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns." [MESH:D032342] +subset: cellxgene_subset synonym: "muscle fiber" EXACT [] synonym: "myocyte" EXACT [] xref: BTO:0000888 @@ -693,6 +724,7 @@ property_value: depiction "https://www.swissbiopics.org/api/image/Muscle_cells.s id: CL:0000192 name: smooth muscle cell def: "A non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels. They develop from specialized myoblasts (smooth muscle myoblast)." [http://en.wikipedia.org/wiki/Smooth_muscle_cell, MESH:D032389, PMID:9315361] +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "myocytes, smooth muscle" EXACT [MESH:D032389] @@ -724,6 +756,7 @@ relationship: part_of UBERON:0001032 ! sensory system id: CL:0000210 name: photoreceptor cell def: "A cell specialized to detect and transduce light." [MESH:D010786] +subset: cellxgene_subset xref: BTO:0001060 xref: CALOHA:TS-0868 xref: FMA:86740 @@ -774,6 +807,7 @@ relationship: part_of UBERON:0000924 ! ectoderm id: CL:0000222 name: mesodermal cell def: "A cell of the middle germ layer of the embryo." [MESH:D008648] +subset: cellxgene_subset synonym: "mesoblast" EXACT [] synonym: "mesoderm cell" EXACT [] xref: FMA:72554 @@ -794,6 +828,7 @@ id: CL:0000232 name: erythrocyte def: "A red blood cell. In mammals, mature erythrocytes are biconcave disks containing hemoglobin whose function is to transport oxygen." [GOC:tfm, MESH:D004912] subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "RBC" EXACT [] synonym: "red blood cell" EXACT [] @@ -818,6 +853,7 @@ relationship: present_in_taxon NCBITaxon:9606 [Term] id: CL:0000255 name: eukaryotic cell +subset: cellxgene_subset xref: MESH:D005057 is_a: CL:0000000 ! cell intersection_of: CL:0000000 ! cell @@ -827,6 +863,7 @@ relationship: only_in_taxon NCBITaxon:2759 ! Eukaryota [Term] id: CL:0000287 name: eye photoreceptor cell +subset: cellxgene_subset subset: eye_upper_slim subset: human_reference_atlas is_a: CL:0000210 ! photoreceptor cell @@ -968,13 +1005,14 @@ is_a: CL:0000211 ! electrically active cell id: CL:0000514 name: smooth muscle myoblast def: "A precursor cell destined to differentiate into smooth muscle myocytes." [GOC:tfm, MESH:D032390] +subset: cellxgene_subset synonym: "myoblast, smooth muscle" EXACT [MESH:D032390] synonym: "satellite cell" RELATED [] xref: FMA:84798 is_a: CL:0000056 ! myoblast intersection_of: CL:0000056 ! myoblast -intersection_of: RO:0002203 CL:0000192 ! develops into smooth muscle cell -relationship: RO:0002203 CL:0000192 ! develops into smooth muscle cell +intersection_of: develops_into CL:0000192 ! smooth muscle cell +relationship: develops_into CL:0000192 ! smooth muscle cell [Term] id: CL:0000526 @@ -989,6 +1027,7 @@ relationship: present_in_taxon NCBITaxon:9606 [Term] id: CL:0000529 name: pigmented epithelial cell +subset: cellxgene_subset is_a: CL:0000710 ! neurecto-epithelial cell [Term] @@ -996,6 +1035,7 @@ id: CL:0000540 name: neuron def: "The basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system." [http://en.wikipedia.org/wiki/Neuron, MESH:D009474] comment: These cells are also reportedly CD4-negative and CD200-positive. They are also capable of producing CD40L and IFN-gamma. +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "nerve cell" EXACT [] @@ -1028,6 +1068,7 @@ id: CL:0000547 name: proerythroblast def: "An immature, nucleated erythrocyte occupying the stage of erythropoeisis that follows formation of erythroid progenitor cells. This cell is CD71-positive, has both a nucleus and a nucleolus, and lacks hematopoeitic lineage markers." [ISBN:0721601464, PMID:1638021] subset: blood_and_immune_upper_slim +subset: cellxgene_subset synonym: "pronormoblast" RELATED [] synonym: "rubriblast" EXACT [ISBN:0721601464] xref: FMA:83518 @@ -1036,6 +1077,7 @@ is_a: CL:0002242 ! nucleate cell is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000764 ! erythroid lineage cell intersection_of: bearer_of PATO:0002505 ! nucleated +intersection_of: bearer_of PATO:0040072 ! high nuclear/cytoplasmic ratio intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M @@ -1048,9 +1090,9 @@ intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell sur intersection_of: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule intersection_of: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G intersection_of: has_part CL:0017503 ! basophilic cytoplasm -intersection_of: has_part CL:0017505 ! increased nucleus size intersection_of: has_part GO:0005730 ! nucleolus intersection_of: RO:0002104 PR:000001945 ! has plasma membrane part transferrin receptor protein 1 +relationship: bearer_of PATO:0040072 ! high nuclear/cytoplasmic ratio relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M @@ -1064,7 +1106,6 @@ relationship: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule relationship: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G relationship: develops_from CL:0000038 ! erythroid progenitor cell relationship: has_part CL:0017503 ! basophilic cytoplasm -relationship: has_part CL:0017505 ! increased nucleus size relationship: has_part GO:0005730 ! nucleolus relationship: RO:0002104 PR:000001945 ! has plasma membrane part transferrin receptor protein 1 @@ -1132,6 +1173,7 @@ id: CL:0000553 name: megakaryocyte progenitor cell def: "The earliest cytologically identifiable precursor in the thrombocytic series. This cell is capable of endomitosis and lacks expression of hematopoieitic lineage markers (lin-negative)." [GOC:dsd, GOC:tfm, ISBN:0721601464] comment: Lineage negative is described here as CD2-negative, CD3-negative, CD4-negative, CD5-negative, CD8a-negative, CD14-negative, CD19-negative, CD20-negative, CD56-negative, Ly6g-negative, and Ter119-negative. +subset: cellxgene_subset subset: human_reference_atlas synonym: "CFU-Meg" EXACT [PMID:11722431, PMID:12482498] synonym: "colony-forming unit-megakaryocyte" EXACT [] @@ -1187,6 +1229,7 @@ name: megakaryocyte def: "A large hematopoietic cell (50 to 100 micron) with a lobated nucleus. Once mature, this cell undergoes multiple rounds of endomitosis and cytoplasmic restructuring to allow platelet formation and release." [http://en.wikipedia.org/wiki/Megakaryocyte, ISBN:0721601464, MESH:D008533, PMID:31043076] comment: Megakaryocytes are reportedly CD181-positive and CD182-positive. subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "megacaryocyte" EXACT [] synonym: "megalocaryocyte" EXACT [] @@ -1205,6 +1248,7 @@ id: CL:0000558 name: reticulocyte def: "An immature erythrocyte that changes the protein composition of its plasma membrane by exosome formation and extrusion. The types of protein removed differ between species though removal of the transferrin receptor is apparent in mammals and birds." [GOC:add, GOC:tfm, PMID:15946868, PMID:2037622] subset: blood_and_immune_upper_slim +subset: cellxgene_subset xref: BTO:0001173 xref: CALOHA:TS-0864 xref: MESH:D012156 @@ -1243,6 +1287,7 @@ relationship: RO:0002104 PR:000001945 ! has plasma membrane part transferrin rec id: CL:0000561 name: amacrine cell def: "Interneuron of the vertebrate retina. They integrate, modulate, and interpose a temporal domain in the visual message presented to the retinal ganglion cells, with which they synapse in the inner plexiform layer. They lack large axons." [GOC:tfm, MESH:D025042, WikipediaVersioned:Amacrine_cell&oldid=1023572246] +subset: cellxgene_subset subset: eye_upper_slim subset: human_reference_atlas synonym: "AC" RELATED OMO:0003000 [doi:10.1038/s41598-020-66092-9] @@ -1280,6 +1325,7 @@ relationship: RO:0002104 PR:000016043 ! has plasma membrane part T-cell acute ly id: CL:0000573 name: retinal cone cell def: "One of the two photoreceptor cell types in the vertebrate retina. In cones the photopigment is in invaginations of the cell membrane of the outer segment. Cones are less sensitive to light than rods, but they provide vision with higher spatial and temporal acuity, and the combination of signals from cones with different pigments allows color vision." [MESH:D017949] +subset: cellxgene_subset subset: human_reference_atlas synonym: "cone" RELATED [doi:10.1038/s41598-020-66092-9] xref: BTO:0001036 @@ -1293,6 +1339,7 @@ relationship: present_in_taxon NCBITaxon:9606 id: CL:0000575 name: corneal epithelial cell def: "An epithelial cell of the cornea." [GOC:tfm] +subset: cellxgene_subset subset: eye_upper_slim subset: human_reference_atlas synonym: "epithelial cell of cornea" EXACT [FMA:70551] @@ -1310,6 +1357,7 @@ relationship: present_in_taxon NCBITaxon:9606 id: CL:0000604 name: retinal rod cell def: "One of the two photoreceptor cell types of the vertebrate retina. In rods the photopigment is in stacks of membranous disks separate from the outer cell membrane. Rods are more sensitive to light than cones, but rod mediated vision has less spatial and temporal resolution than cone vision." [MESH:D017948] +subset: cellxgene_subset subset: human_reference_atlas synonym: "rod" RELATED [doi:10.1038/s41598-020-66092-9] xref: BTO:0001024 @@ -1323,6 +1371,7 @@ relationship: present_in_taxon NCBITaxon:9606 id: CL:0000636 name: Mueller cell def: "Astrocyte-like radial glial cell that extends vertically throughout the retina, with the nucleus are usually in the middle of the inner nuclear layer." [GOC:NV, PMID:21911394] +subset: cellxgene_subset subset: eye_upper_slim subset: human_reference_atlas synonym: "Muller cell" EXACT MISSPELLING [doi:10.21769/BioProtoc.4179] @@ -1338,6 +1387,7 @@ relationship: present_in_taxon NCBITaxon:9606 id: CL:0000679 name: glutamatergic neuron def: "A neuron that is capable of some neurotansmission by glutamate secretion." [] +subset: cellxgene_subset subset: human_reference_atlas xref: FBbt:00100291 xref: WBbt:0006829 @@ -1352,17 +1402,19 @@ relationship: present_in_taxon NCBITaxon:9606 id: CL:0000680 name: muscle precursor cell def: "A non-terminally differentiated cell that is capable of developing into a muscle cell." [GOC:add] +subset: cellxgene_subset is_a: CL:0000055 ! non-terminally differentiated cell intersection_of: CL:0011115 ! precursor cell -intersection_of: RO:0002203 CL:0000187 ! develops into muscle cell +intersection_of: develops_into CL:0000187 ! muscle cell relationship: develops_from CL:0000222 ! mesodermal cell -relationship: RO:0002203 CL:0000187 ! develops into muscle cell +relationship: develops_into CL:0000187 ! muscle cell [Term] id: CL:0000681 name: radial glial cell def: "A cell present in the developing CNS. Functions as both a precursor cell and as a scaffold to support neuronal migration." [GOC:dph] comment: Unlike that of mammals, the brain of adult teleost fish exhibits an intense and widespread neurogenic activity as a result of the persistence of\nradial glial cells acting as neural progenitors throughout life. +subset: cellxgene_subset synonym: "forebrain radial glial cell" NARROW [] is_a: CL:0000125 ! glial cell relationship: develops_from CL:0000710 ! neurecto-epithelial cell @@ -1396,6 +1448,7 @@ relationship: capable_of GO:0048103 ! somatic stem cell division id: CL:0000740 name: retinal ganglion cell def: "The set of neurons that receives neural inputs via bipolar, horizontal and amacrine cells. The axons of these cells make up the optic nerve." [GOC:dph] +subset: cellxgene_subset subset: eye_upper_slim subset: human_reference_atlas synonym: "gangliocyte" EXACT [] @@ -1413,6 +1466,7 @@ relationship: RO:0002100 UBERON:0000966 ! has soma location retina id: CL:0000745 name: retina horizontal cell def: "A neuron that laterally connects other neurons in the inner nuclear layer of the retina." [ISBN:0195088433] +subset: cellxgene_subset subset: eye_upper_slim subset: human_reference_atlas synonym: "HC" RELATED OMO:0003000 [doi:10.1038/s41598-020-66092-9] @@ -1427,6 +1481,7 @@ relationship: RO:0002100 UBERON:0003902 ! has soma location retinal neural layer id: CL:0000748 name: retinal bipolar neuron def: "A bipolar neuron found in the retina and having connections with photoreceptors cells and neurons in the inner plexiform layer." [PMID:14689473] +subset: cellxgene_subset subset: eye_upper_slim subset: human_reference_atlas synonym: "BC" RELATED OMO:0003000 [doi:10.1038/s41598-020-66092-9] @@ -1445,6 +1500,7 @@ relationship: RO:0002100 UBERON:0001791 ! has soma location inner nuclear layer id: CL:0000763 name: myeloid cell def: "A cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage." [GOC:add] +subset: cellxgene_subset xref: BTO:0001441 xref: CALOHA:TS-0647 xref: MESH:D022423 @@ -1458,6 +1514,7 @@ id: CL:0000764 name: erythroid lineage cell def: "A immature or mature cell in the lineage leading to and including erythrocytes." [GOC:add, GOC:tfm] comment: Note that in FMA erythropoietic cells are types of nucleated erythrocytes and thus don't include erythrocytes. +subset: cellxgene_subset subset: human_reference_atlas synonym: "erythropoietic cell" EXACT [] xref: CALOHA:TS-0290 @@ -1471,6 +1528,7 @@ id: CL:0000765 name: erythroblast def: "A nucleated precursor of an erythrocyte that lacks hematopoietic lineage markers." [GOC:add, ISBN:0721601464, PMID:18174176] subset: blood_and_immune_upper_slim +subset: cellxgene_subset synonym: "normoblast" EXACT [] xref: BTO:0001571 xref: CALOHA:TS-0289 @@ -1515,6 +1573,7 @@ name: hematopoietic multipotent progenitor cell def: "A hematopoietic multipotent progenitor cell is multipotent, but not capable of long-term self-renewal. These cells are characterized as lacking lineage cell surface markers and being CD34-positive in both mice and humans." [GOC:add, GOC:tfm, PMID:19022770] comment: Markers differ between mouse and human. subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "hemopoietic progenitor cell" EXACT [] synonym: "MPP" EXACT [] @@ -1562,6 +1621,7 @@ id: CL:0000839 name: myeloid lineage restricted progenitor cell def: "A progenitor cell restricted to the myeloid lineage." [GOC:add, GOC:tfm, PMID:19022770] comment: Note that this is a class of cell types, not an identified single cell type. +subset: cellxgene_subset subset: human_reference_atlas synonym: "myeloid progenitor cell" BROAD [] xref: BTO:0004730 @@ -1578,6 +1638,7 @@ relationship: present_in_taxon NCBITaxon:9606 id: CL:0000988 name: hematopoietic cell def: "A cell of a hematopoietic lineage." [GO_REF:0000031, GOC:add] +subset: cellxgene_subset synonym: "haematopoietic cell" EXACT [] synonym: "haemopoietic cell" EXACT [] synonym: "hemopoietic cell" EXACT [] @@ -1645,6 +1706,7 @@ id: CL:0002139 name: endothelial cell of vascular tree def: "An endothelial cell of the vascular tree, which includes blood vessels and lymphatic vessels." [GOC:dsd, GOC:tfm, PMID:12768659] comment: These cells are reportedly CD31-positive, CD34-positive, CD144-positive, TAL1-positive. +subset: cellxgene_subset synonym: "cubodial endothelial cell of vascular tree" NARROW [] synonym: "vascular endothelial cell" EXACT [] xref: BTO:0001854 @@ -1692,6 +1754,7 @@ id: CL:0002303 name: pigmented ciliary epithelial cell def: "A cell that is part of pigmented ciliary epithelium. This cell type uptakes sodium and chloride ions from stromal interstitium and passes the ions to non-pigmented ciliary epithelial cells via gap junctions." [PMID:15106942] comment: In a consensus model of unidirectional secretion, aqueous humour is formed by transferring solute, principally NaCl, from stroma to posterior chamber, with water passively following the osmotic gradient. Unidirectional secretion comprises three sequential steps. First, NaCl is transferred from the stromal interstitium into the pigmented ciliary epithelial (PE) cells. Second, solute passes from the PE into the non-pigmented ciliary epithelial (NPE) cells through gap junctions. Finally, NPE cells release Na+ and Cl− into the aqueous humour. {xref="https://doi.org/10.1016/j.exer.2003.09.021"} +subset: cellxgene_subset subset: eye_upper_slim subset: human_reference_atlas synonym: "PE cell" EXACT [https://doi.org/10.1016/j.exer.2003.09.021] @@ -1707,6 +1770,7 @@ id: CL:0002304 name: non-pigmented ciliary epithelial cell def: "A cell that is part of non-pigmented ciliary epithelium. This cell type participates in aqueous humor formation by releasing solute, principally sodium and chloride ions received from pigmented epithelial cells via gap junctions, into the aqueous humor of the eye." [GOC:tfm, PMID:15106942] comment: In a consensus model of unidirectional secretion, aqueous humour is formed by transferring solute, principally NaCl, from stroma to posterior chamber, with water passively following the osmotic gradient. Unidirectional secretion comprises three sequential steps. First, NaCl is transferred from the stromal interstitium into the pigmented ciliary epithelial (PE) cells. Second, solute passes from the PE into the non-pigmented ciliary epithelial (NPE) cells through gap junctions. Finally, NPE cells release Na+ and Cl− into the aqueous humour. {xref="https://doi.org/10.1016/j.exer.2003.09.021"} +subset: cellxgene_subset subset: eye_upper_slim subset: human_reference_atlas synonym: "nonpigmented ciliary epithelial cell" EXACT [PMID:10913011] @@ -1722,6 +1786,7 @@ creation_date: 2010-09-13T04:09:31Z id: CL:0002319 name: neural cell def: "A cell that is part of the nervous system." [GOC:tfm, ISBN:0618947256] +subset: cellxgene_subset xref: CALOHA:TS-2040 xref: FMA:70333 is_a: CL:0000000 ! cell @@ -1735,6 +1800,7 @@ creation_date: 2010-09-15T01:34:57Z id: CL:0002320 name: connective tissue cell def: "A cell of the supporting or framework tissue of the body, arising chiefly from the embryonic mesoderm and including adipose tissue, cartilage, and bone." [GOC:tfm, ISBN:0618947256] +subset: cellxgene_subset xref: CALOHA:TS-2096 xref: FMA:63875 xref: MESH:D003239 @@ -1760,6 +1826,7 @@ creation_date: 2010-09-15T03:39:21Z id: CL:0002363 name: keratocyte def: "A keratocyte is a specialized fibroblast residing in the cornea stroma that has a flattened, dendritic morphology; located between the lamellae with a large flattened nucleus, and lengthy processes which communicate with neighboring cells. This corneal layer, representing about 85-90% of corneal thickness, is built up from highly regular collagenous lamellae and extracellular matrix components. Keratocytes play the major role in keeping it transparent, healing its wounds, and synthesizing its components. This cell type secretes collagen I, V, VI, and keratan sulfate." [GOC:tfm, ISBN:9780702029585] +subset: cellxgene_subset subset: eye_upper_slim subset: human_reference_atlas synonym: "corneal fibroblast" EXACT [] @@ -1830,6 +1897,7 @@ creation_date: 2011-03-01T05:28:52Z id: CL:0002585 name: retinal blood vessel endothelial cell def: "A blood vessel endothelial cell that is part of the retina." [GOC:tfm] +subset: cellxgene_subset subset: eye_upper_slim subset: human_reference_atlas is_a: CL:0000071 {is_inferred="true"} ! blood vessel endothelial cell @@ -1845,6 +1913,7 @@ creation_date: 2011-03-06T03:28:27Z id: CL:0002586 name: retinal pigment epithelial cell def: "An epithelial cell of the retinal pigmented epithelium." [GOC:tfm] +subset: cellxgene_subset subset: eye_upper_slim subset: human_reference_atlas xref: BTO:0004910 @@ -1899,6 +1968,7 @@ is_a: CL:0000187 ! muscle cell id: CL:0008001 name: hematopoietic precursor cell def: "Any hematopoietic cell that is a precursor of some other hematopoietic cell type." [GOC:dos] +subset: cellxgene_subset is_a: CL:0000988 ! hematopoietic cell [Term] @@ -1915,6 +1985,7 @@ relationship: part_of UBERON:8600004 ! visceral muscle tissue id: CL:0008019 name: mesenchymal cell def: "A non-polarised cell precursor cell that is part of some mesenchyme, is associated with the cell matrix but is not connected to other cells and is capable of migration." [] +subset: cellxgene_subset subset: human_reference_atlas synonym: "mesenchyme cell" EXACT [] is_a: CL:0000219 ! motile cell @@ -1964,6 +2035,7 @@ relationship: seeAlso https://github.com/obophenotype/cell-ontology/issues/786 id: CL:0011012 name: neural crest cell def: "A cell of the neural crest. Neural crest cells are multipotent. Premigratory neural crest cells are found at the neural plate boarder, some of which will undergo ectomesynchymal transition and delamination to form migratory neural crest cells." [https://orcid.org/0000-0001-5208-3432, https://orcid.org/0000-0002-9900-7880] +subset: cellxgene_subset is_a: CL:0000048 ! multi fate stem cell is_a: CL:0002321 ! embryonic cell (metazoa) @@ -1971,6 +2043,7 @@ is_a: CL:0002321 ! embryonic cell (metazoa) id: CL:0011026 name: progenitor cell def: "A precursor cell that has a tendency to differentiate into a specific type of cell. They are descendants of stem cells, only they are more constrained in their differentiation potential or capacity for self-renewal, and are often more limited in both senses." [https://doi.org/10.1016/B978-0-12-409503-8.00002-0, ISBN:978-1-62808-994-3] +subset: cellxgene_subset is_a: CL:0011115 ! precursor cell intersection_of: CL:0011115 ! precursor cell intersection_of: develops_from CL:0000034 ! stem cell @@ -1992,6 +2065,7 @@ id: CL:0011115 name: precursor cell def: "A cell that, by division or terminal differentiation, can give rise to other cell types." [GOC:dos] comment: Work is needed on GO 'cell differentiation' before it is clear whether the equivalent class definition 'native cell' that capable_of some 'cell differentiation' works. Also, may want to consider merging this with non-terminally differentiated cell. +subset: cellxgene_subset is_a: CL:0000000 ! cell intersection_of: CL:0000000 ! cell intersection_of: capable_of GO:0030154 ! cell differentiation @@ -2031,21 +2105,11 @@ relationship: bearer_of PATO:0070047 ! polychromatophilic relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2009-12-28T04:25:23Z -[Term] -id: CL:0017505 -name: increased nucleus size -def: "A nucleus size quality which is relatively high compared to the amount of cytoplasm present in the same cell." [GOC:tfm] -is_a: GO:0005634 ! nucleus -intersection_of: GO:0005634 ! nucleus -intersection_of: bearer_of PATO:0000586 ! increased size -relationship: bearer_of PATO:0000586 ! increased size -relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 -creation_date: 2009-12-23T10:53:24Z - [Term] id: CL:1000432 name: conjunctival epithelial cell def: "An epithelial cell that is part of the conjunctiva." [GOC:tfm] +subset: cellxgene_subset subset: eye_upper_slim synonym: "epithelial cell of conjunctiva" EXACT [FMA:70552] xref: FMA:70552 @@ -2058,6 +2122,7 @@ relationship: part_of UBERON:0001811 ! conjunctiva id: CL:1000443 name: ciliary muscle cell def: "A smooth muscle cell that is part of the ciliary body." [GOC:tfm] +subset: cellxgene_subset subset: eye_upper_slim synonym: "smooth muscle cell of ciliary body" EXACT [FMA:70610] xref: FMA:70610 @@ -2368,7 +2433,7 @@ id: GO:0005575 name: cellular_component namespace: cellular_component alt_id: GO:0008372 -def: "A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex)." [GOC:pdt] +def: "A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex)." [GOC:pdt] comment: Note that, in addition to forming the root of the cellular component ontology, this term is recommended for the annotation of gene products whose cellular component is unknown. When this term is used for annotation, it indicates that no information was available about the cellular component of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this. subset: goslim_candida subset: goslim_chembl @@ -2399,8 +2464,8 @@ subset: goslim_metagenomics subset: goslim_mouse subset: goslim_pir subset: goslim_plant +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset synonym: "extracellular" EXACT [] xref: Wikipedia:Extracellular is_a: GO:0110165 ! cellular anatomical entity @@ -2459,7 +2524,7 @@ comment: Note that for multicellular organisms, the extracellular space refers t subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "intercellular space" RELATED [] xref: NIF_Subcellular:sao1425028079 is_a: GO:0110165 ! cellular anatomical entity @@ -2523,8 +2588,8 @@ subset: goslim_flybase_ribbon subset: goslim_generic subset: goslim_metagenomics subset: goslim_pir +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset synonym: "chromatid" RELATED [] synonym: "interphase chromosome" NARROW [] synonym: "prophase chromosome" NARROW [] @@ -2558,8 +2623,8 @@ subset: goslim_chembl subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset xref: Wikipedia:Cytoplasm is_a: GO:0110165 ! cellular anatomical entity relationship: part_of GO:0005622 ! intracellular anatomical structure @@ -2577,8 +2642,8 @@ subset: goslim_generic subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset synonym: "free ribosome" NARROW [NIF_Subcellular:sao1139385046] synonym: "membrane bound ribosome" NARROW [NIF_Subcellular:sao1291545653] synonym: "ribosomal RNA" RELATED [] @@ -2603,8 +2668,8 @@ subset: goslim_generic subset: goslim_metagenomics subset: goslim_mouse subset: goslim_plant +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset synonym: "bacterial inner membrane" NARROW [] synonym: "cell membrane" EXACT [] synonym: "cellular membrane" EXACT [NIF_Subcellular:sao6433132645] @@ -2646,7 +2711,7 @@ subset: goslim_drosophila subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "protein anabolism" EXACT [] synonym: "protein biosynthesis" EXACT [] synonym: "protein biosynthetic process" EXACT [] @@ -2718,7 +2783,7 @@ subset: goslim_chembl subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "single-organism transport" RELATED [] is_a: GO:0051234 ! establishment of localization property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20292" xsd:anyURI @@ -3134,7 +3199,7 @@ id: GO:0008219 name: cell death namespace: biological_process def: "Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538)." [GOC:mah, GOC:mtg_apoptosis, PMID:25236395] -comment: This term should not be used for direct annotation, it is currently kept in GO as a placeholder for describing cell death phenotypes in uPHENO. When information is provided on a programmed cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'). Unintentional cell death, i.e. cell death caused by injury, ageing, or cell phenotypes observed as a result of a pathological mutation in an essential gene should NOT be annotated using GO terms. +comment: This term should not be used for direct annotation, it is currently kept in GO as a placeholder for describing cell death phenotypes in uPHENO. When information is provided on a programmed cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'). Unintentional cell death, i.e. cell death caused by injury, ageing, or cell phenotypes observed as a result of a pathological mutation in an essential gene should NOT be annotated using GO terms. subset: gocheck_do_not_annotate synonym: "accidental cell death" RELATED [] synonym: "necrosis" RELATED [] @@ -3373,7 +3438,7 @@ subset: goslim_drosophila subset: goslim_generic subset: goslim_mouse subset: goslim_plant -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "caspase-independent apoptosis" RELATED [] synonym: "caspase-independent cell death" NARROW [] synonym: "non-apoptotic programmed cell death" NARROW [] @@ -3652,8 +3717,8 @@ subset: goslim_flybase_ribbon subset: goslim_generic subset: goslim_mouse subset: goslim_pombe +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset synonym: "biological signaling" EXACT [] synonym: "signaling process" EXACT [] synonym: "signalling" EXACT [] @@ -3680,7 +3745,7 @@ id: GO:0030030 name: cell projection organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon." [GOC:jl, GOC:mah, http://www.cogsci.princeton.edu/~wn/] -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "cell projection organisation" EXACT [] synonym: "cell projection organization and biogenesis" RELATED [GOC:mah] synonym: "cell surface structure organization and biogenesis" RELATED [GOC:mah] @@ -3860,7 +3925,7 @@ subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_pir -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "matrisome" NARROW [] synonym: "proteinaceous extracellular matrix" EXACT [] xref: NIF_Subcellular:nlx_subcell_20090513 @@ -4184,7 +4249,7 @@ subset: goslim_agr subset: goslim_flybase_ribbon subset: goslim_mouse subset: goslim_pir -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "cell process" BROAD [] synonym: "cellular process" BROAD [] synonym: "cellular projection" EXACT [] @@ -4242,12 +4307,14 @@ alt_id: GO:0034960 alt_id: GO:0043283 alt_id: GO:0044259 def: "The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:mah] +subset: gocheck_do_not_annotate subset: goslim_pir synonym: "biopolymer metabolic process" EXACT [GOC:mtg_chebi_dec09] synonym: "macromolecule metabolism" EXACT [] synonym: "multicellular organismal macromolecule metabolic process" NARROW [] synonym: "organismal macromolecule metabolism" EXACT [] is_a: GO:0008152 ! metabolic process +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI [Term] id: GO:0043209 @@ -4273,7 +4340,7 @@ def: "Organized structure of distinctive morphology and function. Includes the n subset: goslim_chembl subset: goslim_generic subset: goslim_pir -subset: prokaryote_subset +subset: goslim_prokaryote xref: NIF_Subcellular:sao1539965131 xref: Wikipedia:Organelle is_a: GO:0110165 ! cellular anatomical entity @@ -4455,9 +4522,11 @@ id: GO:0044238 name: primary metabolic process namespace: biological_process def: "The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism." [GOC:go_curators, http://www.metacyc.org] +subset: gocheck_do_not_annotate subset: goslim_pir synonym: "primary metabolism" EXACT [] is_a: GO:0008152 ! metabolic process +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI [Term] id: GO:0044249 @@ -4643,6 +4712,7 @@ id: GO:0048856 name: anatomical structure development namespace: biological_process def: "The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome." [GO_REF:0000021] +subset: gocheck_do_not_annotate subset: goslim_chembl subset: goslim_generic subset: goslim_plant @@ -4651,6 +4721,7 @@ is_a: GO:0032502 ! developmental process intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of UBERON:0000061 ! anatomical structure relationship: results_in_development_of UBERON:0000061 ! anatomical structure +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI [Term] id: GO:0048869 @@ -4668,7 +4739,7 @@ def: "Any process involved in the controlled self-propelled movement of a cell t subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "cell locomotion" EXACT [] synonym: "cell movement" RELATED [] synonym: "movement of a cell" EXACT [] @@ -4754,7 +4825,7 @@ subset: goslim_agr subset: goslim_flybase_ribbon subset: goslim_mouse subset: goslim_pir -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "physiological response to stimulus" EXACT [] is_a: GO:0008150 ! biological_process @@ -5081,7 +5152,7 @@ subset: goslim_generic subset: goslim_metagenomics subset: goslim_pir subset: goslim_pombe -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "cellular macromolecule complex assembly" RELATED [] synonym: "cellular protein complex assembly" EXACT [] synonym: "cellular protein-containing complex assembly" RELATED [] @@ -5165,10 +5236,12 @@ id: GO:0071704 name: organic substance metabolic process namespace: biological_process def: "The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon." [GOC:mah] +subset: gocheck_do_not_annotate synonym: "organic molecular entity metabolic process" EXACT [] synonym: "organic molecular entity metabolism" EXACT [] synonym: "organic substance metabolism" EXACT [] is_a: GO:0008152 ! metabolic process +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI created_by: mah creation_date: 2010-03-08T03:32:18Z @@ -5208,7 +5281,7 @@ creation_date: 2010-09-10T01:39:16Z id: GO:0071944 name: cell periphery namespace: cellular_component -def: "The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures." [GOC:pdt] +def: "The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures." [GOC:pdt] subset: goslim_flybase_ribbon is_a: GO:0110165 ! cellular anatomical entity created_by: mah @@ -5509,6 +5582,7 @@ subset: goslim_pir is_a: GO:0005575 ! cellular_component is_a: UBERON:0000061 ! anatomical structure property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24200" xsd:anyURI +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI created_by: kmv creation_date: 2019-08-12T18:01:37Z @@ -6018,30 +6092,6 @@ subset: attribute_slim synonym: "relational shape quality" EXACT [] is_a: PATO:0000051 ! morphology -[Term] -id: PATO:0000068 -name: qualitative -namespace: quality -comment: TODO: define this or obsolete it and move children somewhere else. -is_a: PATO:0000001 ! quality - -[Term] -id: PATO:0000069 -name: deviation (from_normal) -namespace: quality -def: "A quality inhering in a bearer by virtue of the whether the bearer differs from normal or average." [PATOC:GVG] -subset: attribute_slim -is_a: PATO:0000068 ! qualitative - -[Term] -id: PATO:0000117 -name: size -namespace: quality -def: "A morphology quality inhering in a bearer by virtue of the bearer's physical magnitude." [WordNet:WordNet] -subset: attribute_slim -subset: scalar_slim -is_a: PATO:0000051 ! morphology - [Term] id: PATO:0000136 name: closure @@ -6086,36 +6136,6 @@ synonym: "round" RELATED [] synonym: "rounded" RELATED [] is_a: PATO:0000947 ! elliptic -[Term] -id: PATO:0000461 -name: normal -namespace: quality -def: "A quality inhering in a bearer by virtue of the bearer's exhibiting no deviation from normal or average." [PATOC:GVG] -subset: abnormal_slim -subset: mpath_slim -subset: value_slim -synonym: "average" RELATED [] -is_a: PATO:0000068 ! qualitative -property_value: RO:0002604 PATO:0000460 - -[Term] -id: PATO:0000586 -name: increased size -namespace: quality -alt_id: PATO:0001202 -def: "A size quality which is relatively high." [PATOC:GVG] -subset: value_slim -synonym: "big" RELATED [] -synonym: "enlarged" RELATED [] -synonym: "expanded" RELATED [] -synonym: "great" RELATED [] -synonym: "large" RELATED [] -is_a: PATO:0000117 ! size -is_a: PATO:0002305 ! increased object quality -intersection_of: PATO:0000117 ! size -intersection_of: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal -property_value: RO:0002604 PATO:0000587 - [Term] id: PATO:0000608 name: closed @@ -6507,32 +6527,6 @@ is_a: PATO:0002078 ! hollow relationship: dc-contributor https://orcid.org/0000-0002-2061-091X creation_date: 2011-06-08T06:33:50Z -[Term] -id: PATO:0002300 -name: increased quality -namespace: quality -def: "A quality that has a value that is increased compared to normal or average." [PATOC:GVG] -is_a: PATO:0000069 ! deviation (from_normal) -intersection_of: PATO:0000001 ! quality -intersection_of: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal -relationship: dc-contributor https://orcid.org/0000-0002-2061-091X -relationship: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal -property_value: RO:0002604 PATO:0002301 -creation_date: 2011-06-16T06:39:43Z - -[Term] -id: PATO:0002305 -name: increased object quality -namespace: quality -def: "A quality of an object that has a value that is increased compared to normal or average." [PATOC:GVG] -is_a: PATO:0001241 ! physical object quality -is_a: PATO:0002300 ! increased quality -intersection_of: PATO:0001241 ! physical object quality -intersection_of: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal -relationship: dc-contributor https://orcid.org/0000-0002-2061-091X -property_value: RO:0002604 PATO:0002303 -creation_date: 2011-06-16T06:54:01Z - [Term] id: PATO:0002309 name: fiber shaped @@ -6606,6 +6600,16 @@ comment: A complete coverage of this domain would subclasses homopolymeric, copo subset: value_slim is_a: PATO:0000141 ! structure +[Term] +id: PATO:0040072 +name: high nuclear/cytoplasmic ratio +namespace: quality +def: "A quality inhering in a cell by virtue of the cell having a high nuclear/cytoplasmic ratio." [http://lymerick.net/blood-cells.pdf, Wikipedia:NC_ratio&oldid=931936284] +comment: A high nuclear/cytolasmic ratio is 70% or higher. +synonym: "high N:C ratio" EXACT [] +is_a: PATO:0001396 ! cellular quality +created_by: http://orcid.org/0000-0001-5208-3432 + [Term] id: PATO:0070006 name: cortical bipolar morphology @@ -7097,7 +7101,7 @@ synonym: "eye" BROAD [FMA:54448] synonym: "eyes" RELATED OMO:0003004 [TAO:0000107] synonym: "orbital part of face" RELATED [FMA:54448] synonym: "orbital region" RELATED [FMA:54448] -synonym: "regio orbitalis" EXACT LATIN [FMA:54448, FMA:TA] +synonym: "regio orbitalis" EXACT OMO:0003011 [FMA:54448, FMA:TA] synonym: "vertebrate eye" NARROW [] xref: AAO:0010340 xref: BIRNLEX:1169 @@ -7152,7 +7156,7 @@ xref: CALOHA:TS-2043 xref: EHDAA2:0001824 xref: EHDAA:500 xref: EMAPA:35955 -xref: FBbt:00005155 +xref: FBbt:00005155 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: GAID:63 xref: HAO:0000930 xref: MA:0000017 @@ -7241,7 +7245,7 @@ def: "Multi-tissue structure that is comprised of a secretory epithelial layer ( subset: uberon_slim subset: vertebrate_core synonym: "serosa" RELATED [Wikipedia:Serous_membrane] -synonym: "tunica serosa" EXACT LATIN [FMA:9581] +synonym: "tunica serosa" EXACT OMO:0003011 [FMA:9581] synonym: "wall of serous sac" EXACT [FMA:9581] xref: FMA:9581 xref: GAID:19 @@ -7320,7 +7324,7 @@ xref: BILA:0000003 xref: CARO:0000003 xref: EHDAA2:0003003 xref: EMAPA:0 -xref: FBbt:00007001 +xref: FBbt:00007001 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:305751 xref: FMA:67135 xref: GAID:781 @@ -7525,7 +7529,7 @@ def: "The surface (external) layer of ectoderm which begins to proliferate short subset: pheno_slim synonym: "surface (external) ectoderm" EXACT [] synonym: "surface ectoderm" EXACT [MP:0012532] -xref: BTO:0006242 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: BTO:0006242 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: EHDAA2:0001968 xref: EHDAA:1494 xref: EHDAA:350 @@ -7638,13 +7642,13 @@ synonym: "fertilized egg stage" RELATED [] synonym: "one cell stage" EXACT [] synonym: "one-cell stage" RELATED [VHOG:0000745] synonym: "zygote" RELATED [VHOG:0000745] -synonym: "zygotum" RELATED LATIN [Wikipedia:Zygote] +synonym: "zygotum" RELATED OMO:0003011 [Wikipedia:Zygote] xref: BilaDO:0000005 xref: BILS:0000106 xref: EFO:0001322 xref: EHDAA:27 xref: FBdv:00005288 -xref: IDOMAL:0000302 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: IDOMAL:0000302 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: NCIT:C12601 xref: PdumDv:0000100 xref: VHOG:0000745 @@ -7791,7 +7795,7 @@ synonym: "funiculus" EXACT [] synonym: "nerve fiber bundle" EXACT [FBbt:00005099] synonym: "neural fiber bundle" EXACT [] xref: CARO:0001001 -xref: FBbt:00005099 +xref: FBbt:00005099 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: NLX:147821 is_a: UBERON:0005162 ! multi cell part structure relationship: has_part GO:0043005 ! neuron projection @@ -7824,13 +7828,13 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "adult mouth" NARROW [] -synonym: "cavital oralis" RELATED LATIN [Wikipedia:Mouth] +synonym: "cavital oralis" RELATED OMO:0003011 [Wikipedia:Mouth] synonym: "cavitas oris" RELATED [BTO:0001090] synonym: "cavum oris" RELATED [BTO:0001090] synonym: "mouth cavity" RELATED [BTO:0001090] synonym: "oral region" RELATED [EHDAA2:0001326] synonym: "oral vestibule" RELATED [BTO:0001090] -synonym: "regio oralis" EXACT LATIN [BTO:0004698, FMA:49184, FMA:TA] +synonym: "regio oralis" EXACT OMO:0003011 [BTO:0004698, FMA:49184, FMA:TA] synonym: "rima oris" RELATED [BTO:0001090] synonym: "stoma" RELATED [] synonym: "stomatodaeum" RELATED [VHOG:0000812] @@ -7845,7 +7849,7 @@ xref: EFO:0000825 xref: EHDAA2:0001326 xref: EHDAA:542 xref: EMAPA:16262 -xref: FBbt:00003126 +xref: FBbt:00003126 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:49184 xref: GAID:75 xref: galen:Mouth @@ -8028,7 +8032,7 @@ xref: CALOHA:TS-2101 xref: CARO:0000004 xref: EHDAA2:0003004 xref: EMAPA:35178 -xref: FBbt:00007019 +xref: FBbt:00007019 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:9669 xref: galen:BodySubstance xref: HAO:0000004 @@ -8063,7 +8067,7 @@ xref: AEO:0000005 xref: BILA:0000005 xref: CARO:0000005 xref: EHDAA2:0003005 -xref: FBbt:00007017 +xref: FBbt:00007017 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:5897 xref: HAO:0000005 xref: NCIT:C94478 @@ -8091,7 +8095,7 @@ xref: AEO:0000006 xref: BILA:0000006 xref: CARO:0000006 xref: EHDAA2:0003006 -xref: FBbt:00007016 +xref: FBbt:00007016 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:67165 xref: HAO:0000006 xref: TAO:0001836 @@ -8117,7 +8121,7 @@ xref: AEO:0000007 xref: BILA:0000007 xref: CARO:0000007 xref: EHDAA2:0003007 -xref: FBbt:00007015 +xref: FBbt:00007015 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:67112 xref: HAO:0000007 xref: TAO:0001835 @@ -8155,11 +8159,11 @@ xref: EHDAA2:0003011 xref: EHDAA:392 xref: EMAPA:16103 xref: EV:0100000 -xref: FBbt:00004856 +xref: FBbt:00004856 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:7149 xref: galen:AnatomicalSystem xref: HAO:0000011 -xref: IDOMAL:0002460 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: IDOMAL:0002460 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: MA:0000003 xref: NCIT:C12919 xref: SCTID:278195005 @@ -8210,7 +8214,7 @@ xref: EHDAA2:0003191 xref: EHDAA:1 xref: EMAPA:25765 xref: EV:0100016 -xref: FBbt:00000001 +xref: FBbt:00000001 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:256135 xref: galen:Organism xref: HAO:0000012 @@ -8255,7 +8259,7 @@ xref: CARO:0000032 xref: EFO:0000808 xref: EHDAA2:0003032 xref: EMAPA:36031 -xref: FBbt:00007009 +xref: FBbt:00007009 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:7153 xref: galen:BodyPart xref: HAO:0000032 @@ -8291,7 +8295,7 @@ xref: AEO:0000040 xref: BILA:0000040 xref: CARO:0000040 xref: EHDAA2:0003040 -xref: FBbt:00007013 +xref: FBbt:00007013 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:63863 xref: HAO:0000040 xref: TAO:0000382 @@ -8311,8 +8315,7 @@ namespace: uberon def: "Anatomical group whose component anatomical structures lie in close proximity to each other." [FBbt:00007277] subset: common_anatomy subset: upper_level -xref: FBbt:00007277 -xref: IDOMAL:0002461 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: FBbt:00007277 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: VHOG:0001737 is_a: UBERON:0034923 ! disconnected anatomical group relationship: present_in_taxon NCBITaxon:33090 @@ -8339,7 +8342,7 @@ xref: CALOHA:TS-2090 xref: CARO:0000043 xref: EHDAA2:0003043 xref: EMAPA:35868 -xref: FBbt:00007003 +xref: FBbt:00007003 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:9637 xref: galen:Tissue xref: HAO:0000043 @@ -8374,7 +8377,7 @@ xref: AEO:0000055 xref: BILA:0000055 xref: CARO:0000055 xref: EHDAA2:0003055 -xref: FBbt:00007010 +xref: FBbt:00007010 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: HAO:0000055 xref: TAO:0001488 xref: TGMA:0001847 @@ -8407,7 +8410,7 @@ xref: CALOHA:TS-0288 xref: CARO:0000066 xref: EHDAA2:0003066 xref: EMAPA:32738 -xref: FBbt:00007005 +xref: FBbt:00007005 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:9639 xref: GAID:402 xref: HAO:0000066 @@ -8584,11 +8587,11 @@ xref: EHDAA2:0000002 xref: EHDAA2_RETIRED:0003236 xref: EHDAA:38 xref: EMAPA:16039 -xref: FBbt:00000052 +xref: FBbt:00000052 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:69068 xref: GAID:963 xref: http://neurolex.org/wiki/Category\:Embryonic_organism -xref: IDOMAL:0000646 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: IDOMAL:0000646 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: MAT:0000226 xref: MESH:D004622 xref: MIAA:0000019 @@ -8628,7 +8631,7 @@ xref: AAO:0000480 xref: BILA:0000035 xref: BTO:0000556 xref: EMAPA:36033 -xref: FBbt:00000110 +xref: FBbt:00000110 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:69069 xref: GAID:1303 xref: MESH:D005855 @@ -8663,7 +8666,7 @@ xref: EFO:0000414 xref: EHDAA2:0000428 xref: EMAPA:16069 xref: EV:0100003 -xref: FBbt:00000111 +xref: FBbt:00000111 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:69070 xref: GAID:1304 xref: MAT:0000155 @@ -8704,7 +8707,7 @@ xref: EFO:0002545 xref: EHDAA2:0000436 xref: EMAPA:16062 xref: EV:0100005 -xref: FBbt:00000125 +xref: FBbt:00000125 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:69071 xref: GAID:1305 xref: MAT:0000175 @@ -8750,7 +8753,7 @@ xref: EHDAA:160 xref: EHDAA:183 xref: EMAPA:16083 xref: EV:0100006 -xref: FBbt:00000126 +xref: FBbt:00000126 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:69072 xref: GAID:522 xref: MAT:0000174 @@ -8794,7 +8797,7 @@ synonym: "stomodeal-hypophyseal primordium" BROAD [XAO:0000269] xref: BTO:0004224 xref: EHDAA2:0001929 xref: EMAPA:16263 -xref: FBbt:00000439 +xref: FBbt:00000439 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:295846 xref: NCIT:C34306 xref: TAO:0001290 @@ -8828,8 +8831,8 @@ synonym: "2n" BROAD OMO:0003000 [BIRNLEX:1640, NIFSTD:NeuroNames_abbrevSource] synonym: "CN-II" RELATED [ZFA:0000435] synonym: "cranial II" EXACT [] synonym: "nerve II" RELATED [NeuroNames:289] -synonym: "nervus opticus" EXACT LATIN [] -synonym: "nervus opticus [II]" EXACT LATIN [FMA:50863, FMA:TA] +synonym: "nervus opticus" EXACT OMO:0003011 [] +synonym: "nervus opticus [II]" EXACT OMO:0003011 [FMA:50863, FMA:TA] synonym: "optic" RELATED [TAO:0000435] synonym: "optic II" EXACT [EHDAA2:0001313] synonym: "optic II nerve" EXACT [EHDAA2:0001313] @@ -8975,7 +8978,7 @@ xref: EHDAA:2641 xref: EHDAA:6485 xref: EMAPA:16894 xref: EV:0100164 -xref: FBbt:00005095 +xref: FBbt:00005095 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:50801 xref: GAID:571 xref: galen:Brain @@ -9040,9 +9043,9 @@ def: "A decussation of the diencephalon where the fibers of the optic nerve cros subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "chiasma" RELATED LATIN [NeuroNames:459] -synonym: "chiasma nervorum opticorum" RELATED LATIN [NeuroNames:459] -synonym: "chiasma opticum" EXACT LATIN [Wikipedia:Optic_chiasm] +synonym: "chiasma" RELATED OMO:0003011 [NeuroNames:459] +synonym: "chiasma nervorum opticorum" RELATED OMO:0003011 [NeuroNames:459] +synonym: "chiasma opticum" EXACT OMO:0003011 [Wikipedia:Optic_chiasm] synonym: "decussation of optic nerve fibers" EXACT [FMA:62045] synonym: "optic chiasm" EXACT [Wikipedia:Optic_chiasm] synonym: "optic chiasm (Rufus of Ephesus)" RELATED [NeuroNames:459] @@ -9260,7 +9263,7 @@ xref: BTO:0000439 xref: CALOHA:TS-0309 xref: EFO:0000827 xref: EV:0100336 -xref: FBbt:00005162 +xref: FBbt:00005162 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: GAID:69 xref: MAT:0000140 xref: MESH:D005123 @@ -9339,7 +9342,7 @@ xref: BTO:0000058 xref: CALOHA:TS-1293 xref: EFO:0000793 xref: EV:0100056 -xref: FBbt:00005055 +xref: FBbt:00005055 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:7152 xref: GAID:278 xref: galen:DigestiveSystem @@ -9378,9 +9381,10 @@ namespace: uberon def: "Organ system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis[WP]." [Wikipedia:Circulatory_system] subset: human_reference_atlas subset: uberon_slim -synonym: "systema cardiovasculare" RELATED LATIN [Wikipedia:Circulatory_system] +synonym: "systema cardiovasculare" RELATED OMO:0003011 [Wikipedia:Circulatory_system] xref: AAO:0000959 xref: CALOHA:TS-2103 +xref: MESH:D002319 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} xref: VHOG:0001248 xref: Wikipedia:Circulatory_system is_a: UBERON:0000467 ! anatomical system @@ -9417,7 +9421,7 @@ synonym: "muscles" RELATED [] synonym: "muscles set" EXACT [] synonym: "musculature" EXACT [] synonym: "musculature system" RELATED [] -synonym: "musculi" EXACT LATIN [FMA:32558, FMA:TA] +synonym: "musculi" EXACT OMO:0003011 [FMA:32558, FMA:TA] synonym: "set of muscles" EXACT [FMA:32558] synonym: "set of skeletal muscles" EXACT [MA:0000165] xref: AAO:0011066 @@ -9448,12 +9452,13 @@ namespace: uberon def: "The nervous system is an organ system containing predominantly neuron and glial cells. In bilaterally symmetrical organism, it is arranged in a network of tree-like structures connected to a central body. The main functions of the nervous system are to regulate and control body functions, and to receive sensory input, process this information, and generate behavior [CUMBO]." [BIRNLEX:844, ISBN:0-14-051288-8, ISBN:3110148986, NLM:nervous+system, WB:rynl, Wikipedia:Nervous_system, ZFIN:curator] subset: cumbo subset: efo_slim +subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "nerve net" NARROW [Wikipedia:Nerve_net] synonym: "neurological system" EXACT [GO:0050877] -synonym: "systema nervosum" RELATED LATIN [Wikipedia:Nervous_system] +synonym: "systema nervosum" RELATED OMO:0003011 [Wikipedia:Nervous_system] xref: AAO:0000324 xref: BILA:0000079 xref: BIRNLEX:844 @@ -9464,7 +9469,7 @@ xref: EHDAA2:0001246 xref: EHDAA:826 xref: EMAPA:16469 xref: EV:0100162 -xref: FBbt:00005093 +xref: FBbt:00005093 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:7157 xref: GAID:466 xref: MA:0000016 @@ -9493,6 +9498,7 @@ relationship: has_part CL:0000540 ! neuron relationship: immediate_transformation_of UBERON:0016880 {source="Bgee:AN"} ! future nervous system relationship: never_in_taxon NCBITaxon:6040 relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa +relationship: present_in_taxon NCBITaxon:9606 property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/b/b2/TE-Nervous_system_diagram.svg" xsd:anyURI property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/b/ba/Nervous_system_diagram.png" xsd:anyURI property_value: UBPROP:0000001 "A regulatory system of the body that consists of neurons and neuroglial cells. The nervous system is divided into two parts, the central nervous system (CNS) and the peripheral nervous system (PNS). (Source: BioGlossary, www.Biology-Text.com)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000396", ontology="TAO", source="ZFIN:curator"} @@ -9508,13 +9514,14 @@ namespace: uberon def: "The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the neural tube derivatives: the brain and spinal cord. In invertebrates it includes central ganglia plus nerve cord." [GO:0021551, http://www.frontiersinzoology.com/content/7/1/29, https://sourceforge.net/p/geneontology/ontology-requests/11422/] subset: cumbo subset: efo_slim +subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "cerebrospinal axis" NARROW [FMA:55675] synonym: "CNS" EXACT OMO:0003000 [] synonym: "neuraxis" RELATED [FMA:55675] -synonym: "systema nervosum centrale" EXACT LATIN [FMA:55675, FMA:TA] +synonym: "systema nervosum centrale" EXACT OMO:0003011 [FMA:55675, FMA:TA] xref: AAO:0000090 xref: BAMS:CNS xref: BILA:0000080 @@ -9527,7 +9534,7 @@ xref: EHDAA:828 xref: EMAPA:16470 xref: EMAPA:16754 xref: EV:0100163 -xref: FBbt:00005094 +xref: FBbt:00005094 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:55675 xref: GAID:570 xref: MA:0000167 @@ -9548,6 +9555,7 @@ relationship: immediate_transformation_of UBERON:0016879 {source="Bgee:AN"} ! fu relationship: never_in_taxon NCBITaxon:147099 {source="Wikipedia:Acoelomorpha"} relationship: only_in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of UBERON:0001016 ! nervous system +relationship: present_in_taxon NCBITaxon:9606 property_value: UBPROP:0000001 "Part of the nervous system which includes the brain and spinal cord.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000090", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000001 "The brain and spinal cord. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000012", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "The central nervous system (CNS) is the part of the nervous system which includes the brain, spinal cord, and nerve cell layer of the retina (CUMBO)." xsd:string {source="BIRNLEX:1099"} @@ -9569,7 +9577,7 @@ synonym: "tract" RELATED [] synonym: "tract of neuraxis" EXACT [FMA:83847] xref: BIRNLEX:1649 xref: EV:0100304 -xref: FBbt:00005100 +xref: FBbt:00005100 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:83847 xref: NLX:147822 is_a: UBERON:0000122 ! neuron projection bundle @@ -9584,7 +9592,7 @@ def: "A slender neuron projection bundle[FBbt]; A bundle of anatomical fibers, a comment: EDITOR_NOTE note FBbt class not disjoint from tract. Consider merging with 'neuron projection bundle' subset: uberon_slim synonym: "fascicle" BROAD [FBbt:00005101] -synonym: "fasciculus" EXACT LATIN [] +synonym: "fasciculus" EXACT OMO:0003011 [] synonym: "nerve bundle" EXACT [FMA:12235] synonym: "nerve fasciculus" EXACT [FMA:12235] synonym: "nerve fiber tract" RELATED [BTO:0002191] @@ -9607,8 +9615,8 @@ def: "Anatomical system that overlaps the nervous system and is responsible for subset: efo_slim subset: uberon_slim subset: vertebrate_core -synonym: "organa sensuum" EXACT LATIN [FMA:75259, FMA:TA] -synonym: "organa sensuum" RELATED LATIN [Wikipedia:Sensory_system] +synonym: "organa sensuum" EXACT OMO:0003011 [FMA:75259, FMA:TA] +synonym: "organa sensuum" RELATED OMO:0003011 [Wikipedia:Sensory_system] synonym: "sense organ subsystem" EXACT [] synonym: "sense organs" EXACT [FMA:75259] synonym: "sense organs set" EXACT [FMA:75259] @@ -9622,7 +9630,7 @@ xref: BILA:0000099 xref: EFO:0000805 xref: EHDAA2:0003094 xref: EMAPA:16192 -xref: FBbt:00007692 +xref: FBbt:00007692 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:75259 xref: MA:0002442 xref: MAT:0000031 @@ -9658,7 +9666,7 @@ xref: AEO:0000171 xref: BTO:0001886 xref: EFO:0001652 xref: EHDAA2:0003171 -xref: FBbt:00005495 +xref: FBbt:00005495 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:86589 xref: MAT:0000482 xref: NCIT:C34275 @@ -9678,7 +9686,7 @@ subset: uberon_slim subset: vertebrate_core synonym: "neural primordium" RELATED [] synonym: "presumptive central nervous system" RELATED [] -synonym: "tubus neuralis" RELATED LATIN [Wikipedia:Neural_tube] +synonym: "tubus neuralis" RELATED OMO:0003011 [Wikipedia:Neural_tube] xref: AAO:0010617 xref: BTO:0001057 xref: CALOHA:TS-2371 @@ -9690,7 +9698,7 @@ xref: EMAPA:16164 xref: EMAPA:16757 xref: FMA:293882 xref: MAT:0000069 -xref: MESH:D054259 +xref: MESH:D054259 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: MIAA:0000069 xref: NCIT:C34226 xref: neuronames:1365 @@ -9726,7 +9734,7 @@ xref: BILA:0000000 xref: BIRNLEX:6 xref: CARO:0000000 xref: EHDAA2:0002229 -xref: FBbt:10000000 +xref: FBbt:10000000 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:62955 xref: HAO:0000000 xref: MA:0000001 @@ -9753,8 +9761,8 @@ subset: vertebrate_core synonym: "involuntary muscle" EXACT [] synonym: "non-striated muscle" EXACT [] synonym: "smooth muscle" EXACT [] -synonym: "textus muscularis levis; textus muscularis nonstriatus" RELATED LATIN [Wikipedia:Smooth_muscle_tissue] -synonym: "textus muscularis nonstriatus" EXACT LATIN [FMA:14070, FMA:TA] +synonym: "textus muscularis levis; textus muscularis nonstriatus" RELATED OMO:0003011 [Wikipedia:Smooth_muscle_tissue] +synonym: "textus muscularis nonstriatus" EXACT OMO:0003011 [FMA:14070, FMA:TA] synonym: "visceral muscle" NARROW SENSU [] synonym: "visceral muscle tissue" NARROW SENSU [] xref: AAO:0010244 @@ -9920,7 +9928,7 @@ namespace: uberon def: "A subdivision of the head that has as parts the layers deep to the surface of the anterior surface, including the mouth, eyes, and nose (when present). In vertebrates, this includes the facial skeleton and structures superficial to the facial skeleton (cheeks, mouth, eyeballs, skin of face, etc)." [http://orcid.org/0000-0002-6601-2165] subset: pheno_slim subset: uberon_slim -synonym: "facia/facies" RELATED LATIN [Wikipedia:Face] +synonym: "facia/facies" RELATED OMO:0003011 [Wikipedia:Face] synonym: "visage" RELATED [BTO:0003369] xref: BTO:0003369 xref: CALOHA:TS-2216 @@ -9966,10 +9974,11 @@ xref: BTO:0000545 xref: EHDAA2:0000726 xref: EHDAA:518 xref: EMAPA:16247 -xref: FBbt:00003125 +xref: FBbt:00003125 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:45615 xref: galen:AlimentaryTract xref: MA:0000917 +xref: MESH:D041981 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} xref: NCIT:C34082 xref: TAO:0000112 xref: TGMA:0001819 @@ -10001,7 +10010,7 @@ subset: pheno_slim subset: uberon_slim synonym: "Bowman`s muscles" RELATED [BTO:0000654] synonym: "ciliaris" RELATED [Wikipedia:Ciliary_muscle] -synonym: "musculus ciliaris" RELATED LATIN [Wikipedia:Ciliary_muscle] +synonym: "musculus ciliaris" RELATED OMO:0003011 [Wikipedia:Ciliary_muscle] synonym: "musculus ciliarus" EXACT [BTO:0000654] xref: BTO:0000654 xref: EMAPA:35240 @@ -10100,7 +10109,7 @@ synonym: "anterior chamber" EXACT [HP:0000593, MP:0010709] synonym: "anterior chamber of eye" EXACT [] synonym: "camera anterior" EXACT [] synonym: "camera anterior bulbi" RELATED [BTO:0002084] -synonym: "camera anterior bulbi oculi" RELATED LATIN [Wikipedia:Anterior_chamber_of_eyeball] +synonym: "camera anterior bulbi oculi" RELATED OMO:0003011 [Wikipedia:Anterior_chamber_of_eyeball] synonym: "camera oculi anterior" RELATED [BTO:0002084] synonym: "eye anterior chamber" EXACT [] xref: BTO:0002084 @@ -10132,7 +10141,7 @@ subset: pheno_slim subset: uberon_slim synonym: "pars iridica retinae" RELATED [Wikipedia:Uvea] synonym: "tunica vasculatis oculi" RELATED [Wikipedia:Uvea] -synonym: "tunica vasculosa bulbi" RELATED LATIN [Wikipedia:Uvea] +synonym: "tunica vasculosa bulbi" RELATED OMO:0003011 [Wikipedia:Uvea] synonym: "tunica vasculosa of eyeball" EXACT [FMA:58103] synonym: "uvea" EXACT [FMA:58103] synonym: "uveal tract" EXACT [FMA:58103] @@ -10214,13 +10223,13 @@ synonym: "anterior corneal epithelium" EXACT [] synonym: "anterior endothelium of cornea" RELATED [BTO:0000287] synonym: "cornea epithelial tissue" EXACT [OBOL:automatic] synonym: "cornea epithelium" EXACT [OBOL:automatic] -synonym: "e. anterius corneae" RELATED LATIN [Wikipedia:Corneal_epithelium] +synonym: "e. anterius corneae" RELATED OMO:0003011 [Wikipedia:Corneal_epithelium] synonym: "endothelium anterius corneae" RELATED [BTO:0000287] synonym: "endothelium camerae anterioris bulbi" RELATED [BTO:0000287] synonym: "endothelium corneale" RELATED [BTO:0000287] synonym: "epithelial tissue of cornea" EXACT [OBOL:automatic] synonym: "epithelium anterius (cornea)" EXACT [] -synonym: "epithelium anterius corneae" EXACT LATIN [FMA:58263, FMA:TA] +synonym: "epithelium anterius corneae" EXACT OMO:0003011 [FMA:58263, FMA:TA] synonym: "epithelium corneæ anterior layer" EXACT [] synonym: "epithelium of cornea" EXACT [] synonym: "epithelium posterius corneae" RELATED [BTO:0000287] @@ -10306,7 +10315,7 @@ subset: uberon_slim subset: vertebrate_core synonym: "anterior uvea" RELATED [] synonym: "ciliary bodies" RELATED OMO:0003004 [VHOG:0000102] -synonym: "corpus ciliare" RELATED LATIN [Wikipedia:Ciliary_body] +synonym: "corpus ciliare" RELATED OMO:0003011 [Wikipedia:Ciliary_body] synonym: "ocular ciliary body" EXACT [] xref: AAO:0010341 xref: BTO:0000260 @@ -10348,7 +10357,7 @@ synonym: "chorioid" RELATED [BTO:0001829] synonym: "choroid" EXACT [MA:0000263] synonym: "choroid coat" EXACT [Wikipedia:Choroid] synonym: "choroidea" EXACT [Wikipedia:Choroid] -synonym: "choroidea" RELATED LATIN [Wikipedia:Choroid] +synonym: "choroidea" RELATED OMO:0003011 [Wikipedia:Choroid] synonym: "eye choroid" EXACT [VHOG:0001568] synonym: "optic choroid" RELATED [ZFA:0005229] synonym: "posterior uvea" EXACT [Wikipedia:Uvea#Regions] @@ -10394,7 +10403,7 @@ subset: vertebrate_core synonym: "corneal stroma" EXACT [MA:0001245] synonym: "stroma of cornea" EXACT [] synonym: "substantia propria" BROAD [] -synonym: "substantia propria corneae" EXACT LATIN [FMA:58306, FMA:TA] +synonym: "substantia propria corneae" EXACT OMO:0003011 [FMA:58306, FMA:TA] xref: CALOHA:TS-1138 xref: EFO:0002514 xref: EMAPA:17602 @@ -10483,7 +10492,7 @@ subset: uberon_slim subset: vertebrate_core synonym: "epithelium, retinal pigment" RELATED [BTO:0001177] synonym: "outer pigmented layer of retina" EXACT [] -synonym: "p. pigmentosa retinae" RELATED LATIN [Wikipedia:Retinal_pigment_epithelium] +synonym: "p. pigmentosa retinae" RELATED OMO:0003011 [Wikipedia:Retinal_pigment_epithelium] synonym: "pigment epithelium of retina" EXACT [] synonym: "pigmented epithelium" RELATED [] synonym: "pigmented retina" RELATED [] @@ -10494,9 +10503,9 @@ synonym: "retinal pigment epithelium" EXACT [MP:0005201, Wikipedia:Retinal_pigme synonym: "retinal pigment layer" RELATED [VHOG:0000536] synonym: "retinal pigmented epithelium" EXACT [ZFA:0000144] synonym: "RPE" RELATED [] -synonym: "stratum pigmentosa retinae" RELATED LATIN [Wikipedia:Retinal_pigment_epithelium] +synonym: "stratum pigmentosa retinae" RELATED OMO:0003011 [Wikipedia:Retinal_pigment_epithelium] synonym: "stratum pigmentosum (retina)" EXACT [] -synonym: "stratum pigmentosum retinae" EXACT LATIN [FMA:58627, FMA:TA] +synonym: "stratum pigmentosum retinae" EXACT OMO:0003011 [FMA:58627, FMA:TA] xref: AAO:0011096 xref: BTO:0001177 xref: CALOHA:TS-0869 @@ -10544,7 +10553,7 @@ synonym: "retina photoreceptor layer" EXACT [] synonym: "retinal photoreceptor layer" EXACT [ZFA:0000143] synonym: "retinal photoreceptor layers" RELATED OMO:0003004 [ZFA:0000143] synonym: "stratum segmentorum externorum et internorum (retina)" EXACT [] -synonym: "stratum segmentorum externorum et internorum retinae" EXACT LATIN [FMA:58680, FMA:TA] +synonym: "stratum segmentorum externorum et internorum retinae" EXACT OMO:0003011 [FMA:58680, FMA:TA] xref: EMAPA:35686 xref: FMA:58680 xref: MA:0001308 @@ -10581,7 +10590,7 @@ synonym: "outer limiting membranes" RELATED OMO:0003004 [ZFA:0001331] synonym: "retina external limiting lamina" EXACT [] synonym: "retina outer limiting membrane" EXACT [MP:0010236] synonym: "stratum limitans externum (retina)" EXACT [] -synonym: "stratum limitans externum retinae" EXACT LATIN [FMA:58683, FMA:TA] +synonym: "stratum limitans externum retinae" EXACT OMO:0003011 [FMA:58683, FMA:TA] xref: EMAPA:36518 xref: FMA:58683 xref: MA:0001309 @@ -10613,7 +10622,7 @@ synonym: "retina, outer nuclear layer" RELATED [BAMS:Ronl] synonym: "retinal outer nuclear layer" EXACT [] synonym: "retinal outer nuclear layers" RELATED OMO:0003004 [ZFA:0001464] synonym: "stratum nucleare externum (retina)" EXACT [] -synonym: "stratum nucleare externum retinae" EXACT LATIN [FMA:58684, FMA:TA] +synonym: "stratum nucleare externum retinae" EXACT OMO:0003011 [FMA:58684, FMA:TA] xref: BAMS:Ronl xref: BTO:0005600 xref: EMAPA:19157 @@ -10650,7 +10659,7 @@ synonym: "retina, outer plexiform layer" RELATED [BAMS:Ropl] synonym: "retinal outer plexiform layer" EXACT [] synonym: "retinal outer plexiform layers" RELATED OMO:0003004 [ZFA:0001330] synonym: "stratum plexiforme externum" EXACT [] -synonym: "stratum plexiforme externum retinae" EXACT LATIN [FMA:58685, FMA:TA] +synonym: "stratum plexiforme externum retinae" EXACT OMO:0003011 [FMA:58685, FMA:TA] xref: BAMS:Ropl xref: BTO:0003174 xref: EMAPA:35744 @@ -10689,7 +10698,7 @@ synonym: "retina inner nuclear layer" EXACT [] synonym: "retina, inner nuclear layer" RELATED [BAMS:Rinl] synonym: "retinal inner nuclear layer" EXACT [] synonym: "stratum nucleare internum" EXACT [] -synonym: "stratum nucleare internum retinae" EXACT LATIN [FMA:58686, FMA:TA] +synonym: "stratum nucleare internum retinae" EXACT OMO:0003011 [FMA:58686, FMA:TA] xref: BAMS:Rinl xref: BTO:0003176 xref: EMAPA:19155 @@ -10735,7 +10744,7 @@ synonym: "retinal ganglion cell layer" EXACT [] synonym: "retinal ganglion layer" EXACT [MP:0008510] synonym: "RGC layer" EXACT [] synonym: "stratum ganglionicum (retina)" EXACT [FMA:58687] -synonym: "stratum ganglionicum retinae" RELATED LATIN [Wikipedia:Ganglion_cell_layer] +synonym: "stratum ganglionicum retinae" RELATED OMO:0003011 [Wikipedia:Ganglion_cell_layer] xref: BAMS:Rgcl xref: BTO:0003398 xref: CALOHA:TS-0867 @@ -10779,8 +10788,8 @@ synonym: "optic fiber layer" RELATED [VHOG:0001169] synonym: "optic fiber layers" RELATED OMO:0003004 [TAO:0002212] synonym: "retina nerve fiber layer" EXACT [] synonym: "stratum neurofibrarum (retina)" EXACT [] -synonym: "stratum neurofibrarum retinae" EXACT LATIN [FMA:58688, FMA:TA] -synonym: "stratum neurofibrum retinae" RELATED LATIN [Wikipedia:Nerve_fiber_layer] +synonym: "stratum neurofibrarum retinae" EXACT OMO:0003011 [FMA:58688, FMA:TA] +synonym: "stratum neurofibrum retinae" RELATED OMO:0003011 [Wikipedia:Nerve_fiber_layer] synonym: "stratum opticum of retina" EXACT [] xref: DMBA:15652 xref: EMAPA:18591 @@ -10815,7 +10824,7 @@ synonym: "internal limiting lamina of retina" EXACT [] synonym: "internal limiting membrane of retina" EXACT [] synonym: "retina inner limiting membrane" EXACT [MP:0010235] synonym: "retina internal limiting lamina" EXACT [] -synonym: "stratum limitans internum retinae" EXACT LATIN [FMA:58689, FMA:TA] +synonym: "stratum limitans internum retinae" EXACT OMO:0003011 [FMA:58689, FMA:TA] xref: EMAPA:36519 xref: FMA:58689 xref: MA:0001313 @@ -10850,7 +10859,7 @@ synonym: "retinal inner plexiform layer" EXACT [] synonym: "retinal internal plexiform layer" RELATED [NLXANAT:1005032] synonym: "stratum plexifome internum" RELATED [BTO:0003175] synonym: "stratum plexiforme internum" EXACT [FMA:58704] -synonym: "stratum plexiforme internum retinae" RELATED LATIN [Wikipedia:Inner_plexiform_layer] +synonym: "stratum plexiforme internum retinae" RELATED OMO:0003011 [Wikipedia:Inner_plexiform_layer] xref: BAMS:Ripl xref: BTO:0003175 xref: EMAPA:35741 @@ -10893,7 +10902,7 @@ subset: uberon_slim subset: vertebrate_core synonym: "aqueous humor" EXACT [] synonym: "aqueous humour" EXACT [EHDAA2:0000139] -synonym: "humor aquosus" EXACT LATIN [FMA:58819, FMA:TA] +synonym: "humor aquosus" EXACT OMO:0003011 [FMA:58819, FMA:TA] xref: EHDAA2:0000139 xref: EHDAA:10196 xref: EMAPA:18232 @@ -10926,7 +10935,7 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "humor vitreous" EXACT [] -synonym: "humor vitreus" EXACT LATIN [FMA:58822, FMA:TA] +synonym: "humor vitreus" EXACT OMO:0003011 [FMA:58822, FMA:TA] synonym: "humoral fluid" RELATED [BTO:0001451] synonym: "ocular fluid" RELATED [BTO:0001451] synonym: "portion of vitreous humor" BROAD [FMA:67388] @@ -10941,6 +10950,7 @@ xref: ENVO:02000032 xref: EV:0100344 xref: FMA:58822 xref: MA:0001286 +xref: MESH:D014822 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} xref: NCIT:C13323 xref: UMLS:C0229096 {source="ncithesaurus:Vitreous_Humor"} xref: VHOG:0000795 @@ -10982,7 +10992,7 @@ namespace: uberon def: "The chamber in the eyeball enclosing the vitreous humor, bounded anteriorly by the lens and ciliary body and posteriorly by the posterior wall of the eyeball[BTO,modified]." [BTO:0002087] subset: uberon_slim synonym: "camera postrema" EXACT [FMA:58848] -synonym: "camera postrema bulbi oculi" EXACT LATIN [FMA:58848, FMA:TA] +synonym: "camera postrema bulbi oculi" EXACT OMO:0003011 [FMA:58848, FMA:TA] synonym: "camera vitrea" EXACT [FMA:58848] synonym: "camera vitrea bulbi" EXACT [FMA:58848] synonym: "postremal chamber" EXACT [FMA:58848] @@ -11014,7 +11024,7 @@ synonym: "anterior segment of eye" EXACT [] synonym: "anterior segment of the eye" EXACT [] synonym: "eye anterior segment" EXACT [] synonym: "segmentum anterius (bulbus oculi)" EXACT [] -synonym: "segmentum anterius bulbi oculi" RELATED LATIN [Wikipedia:Anterior_segment_of_eyeball] +synonym: "segmentum anterius bulbi oculi" RELATED OMO:0003011 [Wikipedia:Anterior_segment_of_eyeball] xref: EMAPA:36594 xref: FMA:58865 xref: MA:0002484 @@ -11045,7 +11055,7 @@ synonym: "posterior segment eye" EXACT [ZFA:0005567] synonym: "posterior segment of eye" EXACT [] synonym: "posterior segment of the eye" EXACT [] synonym: "segmentum posterius (bulbus oculi)" EXACT [] -synonym: "segmentum posterius bulbi oculi" RELATED LATIN [Wikipedia:Posterior_segment_of_eyeball] +synonym: "segmentum posterius bulbi oculi" RELATED OMO:0003011 [Wikipedia:Posterior_segment_of_eyeball] xref: EMAPA:36595 xref: FMA:58868 xref: MA:0002485 @@ -11071,7 +11081,7 @@ subset: pheno_slim subset: uberon_slim synonym: "conjunctivae" EXACT OMO:0003004 [XAO:0000182] synonym: "conjunctivas" EXACT OMO:0003004 [XAO:0000182] -synonym: "tunica conjunctiva" EXACT LATIN [FMA:TA] +synonym: "tunica conjunctiva" EXACT OMO:0003011 [FMA:TA] synonym: "wall of conjunctival sac" EXACT [FMA:59011] xref: AAO:0010343 xref: BTO:0003415 @@ -11162,7 +11172,7 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "MB" BROAD OMO:0003000 [BIRNLEX:1667, NIFSTD:NeuroNames_abbrevSource] -synonym: "mesencephalon" RELATED LATIN [Wikipedia:Midbrain] +synonym: "mesencephalon" RELATED OMO:0003011 [Wikipedia:Midbrain] xref: AAO:0010149 xref: BAMS:MES xref: BIRNLEX:1667 @@ -11222,7 +11232,7 @@ subset: vertebrate_core synonym: "between brain" EXACT [] synonym: "betweenbrain" RELATED [BTO:0000342] synonym: "DiE" BROAD OMO:0003000 [BIRNLEX:1503, NIFSTD:NeuroNames_abbrevSource] -synonym: "diencephalon" RELATED LATIN [Wikipedia:Diencephalon] +synonym: "diencephalon" RELATED OMO:0003011 [Wikipedia:Diencephalon] synonym: "interbrain" EXACT [Swanson:2004] synonym: "mature diencephalon" EXACT [FMA:62001] synonym: "thalamencephalon" EXACT [MGI:anna] @@ -11291,9 +11301,9 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "bulb" BROAD [] -synonym: "bulbus" EXACT LATIN [FMA:62004, FMA:TA] +synonym: "bulbus" EXACT OMO:0003011 [FMA:62004, FMA:TA] synonym: "medulla" BROAD [ABA:MY] -synonym: "medulla oblonzata" RELATED LATIN [Wikipedia:Medulla_oblongata] +synonym: "medulla oblonzata" RELATED OMO:0003011 [Wikipedia:Medulla_oblongata] synonym: "metepencephalon" RELATED [FMA:62004] xref: AAO:0010486 xref: BAMS:Md @@ -11349,8 +11359,8 @@ subset: uberon_slim subset: vertebrate_core synonym: "optic lemniscus" EXACT [] synonym: "optic tracts" RELATED OMO:0003004 [ZFA:0000252] -synonym: "tractus optici" RELATED LATIN [NeuroNames:460] -synonym: "tractus opticus" RELATED LATIN [Wikipedia:Optic_tract] +synonym: "tractus optici" RELATED OMO:0003011 [NeuroNames:460] +synonym: "tractus opticus" RELATED OMO:0003011 [Wikipedia:Optic_tract] synonym: "visual pathway" RELATED [GAID:735] xref: BAMS:opt xref: BIRNLEX:1684 @@ -11401,8 +11411,8 @@ subset: vertebrate_core synonym: "mesencephalic tegmentum" RELATED [VHOG:0001367] synonym: "MTg" BROAD OMO:0003000 [BIRNLEX:1200, NIFSTD:NeuroNames_abbrevSource] synonym: "tegmentum" BROAD [ISBN:0471888893] -synonym: "tegmentum mesencephali" EXACT LATIN [Wikipedia:Midbrain_tegmentum] -synonym: "tegmentum mesencephalicum" RELATED LATIN [NeuroNames:491] +synonym: "tegmentum mesencephali" EXACT OMO:0003011 [Wikipedia:Midbrain_tegmentum] +synonym: "tegmentum mesencephalicum" RELATED OMO:0003011 [NeuroNames:491] synonym: "tegmentum of midbrain" EXACT [] xref: BAMS:MTg xref: BIRNLEX:1200 @@ -11415,6 +11425,7 @@ xref: FMA:62393 xref: HBA:9002 xref: MA:0000212 xref: MAT:0000452 +xref: MESH:D013681 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} xref: neuronames:491 {source="BIRNLEX:1200"} xref: SCTID:362392007 xref: TAO:0000160 @@ -11478,7 +11489,7 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "region of vascular tree organ" EXACT [FMA:50722] -synonym: "vas sanguineum" RELATED LATIN [Wikipedia:Blood_vessel] +synonym: "vas sanguineum" RELATED OMO:0003011 [Wikipedia:Blood_vessel] synonym: "vascular element" BROAD [EMAPA:35993] synonym: "vascular tree organ region" EXACT [FMA:50722] xref: AAO:0011004 @@ -11535,7 +11546,7 @@ subset: uberon_slim subset: vertebrate_core synonym: "cornea endothelium" EXACT [OBOL:automatic] synonym: "endothelium of cornea" EXACT [OBOL:automatic] -synonym: "epithelium posterius corneae" RELATED LATIN [Wikipedia:Corneal_endothelium] +synonym: "epithelium posterius corneae" RELATED OMO:0003011 [Wikipedia:Corneal_endothelium] xref: CALOHA:TS-0172 xref: EMAPA:35935 xref: FMA:63882 @@ -11602,9 +11613,9 @@ synonym: "gray matter of neuraxis" EXACT [FMA:67242] synonym: "grey matter" EXACT [] synonym: "grey matter of neuraxis" EXACT [] synonym: "grey substance" EXACT [] -synonym: "grisea" RELATED LATIN [] +synonym: "grisea" RELATED OMO:0003011 [] synonym: "neuronal grey matter" EXACT [AEO:0001012] -synonym: "substantia grisea" EXACT LATIN [FMA:67242, FMA:TA] +synonym: "substantia grisea" EXACT OMO:0003011 [FMA:67242, FMA:TA] xref: AEO:0001012 xref: EHDAA2:0003136 xref: EHDAA2_RETIRED:0004658 @@ -11612,7 +11623,7 @@ xref: EMAPA:37596 {source="MA:th"} xref: FMA:67242 xref: HBA:4006 xref: MA:0001112 -xref: MESH:D066128 +xref: MESH:D066128 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: NCIT:C32695 xref: neuronames:2869 xref: TAO:0002197 @@ -11723,7 +11734,7 @@ xref: BILA:0000034 xref: BTO:0000174 xref: CALOHA:TS-2110 xref: EFO:0000461 -xref: FBbt:00004208 +xref: FBbt:00004208 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:69067 xref: GAID:407 xref: MESH:D004628 @@ -11799,6 +11810,7 @@ xref: EMAPA:37721 {source="MA:th"} xref: FMA:71221 xref: MA:0002986 xref: MAT:0000148 +xref: MESH:D013131 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} xref: MIAA:0000148 xref: TAO:0000317 xref: VHOG:0000317 @@ -11993,7 +12005,7 @@ namespace: uberon def: "The part of the coelemic cavity lumen that is enclosed by the walls of the thorax." [UBERON:cjm, Wikipedia:Thoracic_cavity] subset: pheno_slim subset: uberon_slim -synonym: "cavitas thoracis" EXACT LATIN [Wikipedia:Thoracic_cavity] +synonym: "cavitas thoracis" EXACT OMO:0003011 [Wikipedia:Thoracic_cavity] synonym: "cavity of chest" EXACT [] synonym: "cavity of thorax" EXACT [] synonym: "chest cavity" EXACT [] @@ -12034,9 +12046,9 @@ subset: uberon_slim subset: vertebrate_core synonym: "cerebro-cerebellar fissure" RELATED [NeuroNames:22] synonym: "cerebrocerebellar fissure" RELATED [NeuroNames:22] -synonym: "fissura cerebro-cerebellaris" RELATED LATIN [NeuroNames:22] -synonym: "fissura cerebrocerebellaris" RELATED LATIN [NeuroNames:22] -synonym: "medulla spinalis" RELATED LATIN [BTO:0001279, Wikipedia:Spinal_cord] +synonym: "fissura cerebro-cerebellaris" RELATED OMO:0003011 [NeuroNames:22] +synonym: "fissura cerebrocerebellaris" RELATED OMO:0003011 [NeuroNames:22] +synonym: "medulla spinalis" RELATED OMO:0003011 [BTO:0001279, Wikipedia:Spinal_cord] synonym: "SpC" RELATED OMO:0003000 [] synonym: "spinal cord structure" RELATED [ZFA:0000075] synonym: "spinal medulla" RELATED [BTO:0001279] @@ -12099,12 +12111,12 @@ subset: uberon_slim subset: vertebrate_core synonym: "accessory medullary lamina of pallidum" RELATED [NeuroNames:236] synonym: "brain stem" EXACT [ABA:BS] -synonym: "lamella pallidi incompleta" RELATED LATIN [NeuroNames:236] -synonym: "lamina medullaris accessoria" RELATED LATIN [NeuroNames:236] -synonym: "lamina medullaris incompleta pallidi" RELATED LATIN [NeuroNames:236] -synonym: "lamina pallidi incompleta" RELATED LATIN [NeuroNames:236] -synonym: "truncus encephali" EXACT LATIN [Wikipedia:Brainstem] -synonym: "truncus encephalicus" RELATED LATIN [BTO:0000146] +synonym: "lamella pallidi incompleta" RELATED OMO:0003011 [NeuroNames:236] +synonym: "lamina medullaris accessoria" RELATED OMO:0003011 [NeuroNames:236] +synonym: "lamina medullaris incompleta pallidi" RELATED OMO:0003011 [NeuroNames:236] +synonym: "lamina pallidi incompleta" RELATED OMO:0003011 [NeuroNames:236] +synonym: "truncus encephali" EXACT OMO:0003011 [Wikipedia:Brainstem] +synonym: "truncus encephalicus" RELATED OMO:0003011 [BTO:0000146] xref: BAMS:BS xref: BIRNLEX:1565 xref: BTO:0000146 @@ -12148,7 +12160,7 @@ synonym: "CNS tract/commissure" EXACT [ZFA:0001682] synonym: "CNS tracts and commissures" RELATED [TAO:0000145] synonym: "CNS white matter" RELATED [TAO:0002143] synonym: "neuronal white matter" EXACT [AEO:0001011] -synonym: "substantia alba" RELATED LATIN [Wikipedia:White_matter] +synonym: "substantia alba" RELATED OMO:0003011 [Wikipedia:White_matter] synonym: "white mater" RELATED [VHOG:0001764] synonym: "white matter of neuraxis" EXACT [FMA:83929] synonym: "white substance" EXACT [] @@ -12158,7 +12170,7 @@ xref: EMAPA:35927 xref: FMA:83929 xref: HBA:9218 xref: MA:0001135 -xref: MESH:D066127 +xref: MESH:D066127 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: NCIT:C33892 xref: neuronames:2870 xref: NLX:412 @@ -12202,7 +12214,7 @@ synonym: "ventral body cavity" NARROW [NCBITaxon:7742] xref: AEO:0000186 xref: BTO:0001707 xref: EHDAA2:0000267 -xref: FBbt:00005060 +xref: FBbt:00005060 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:85006 xref: galen:BodyCavity xref: NCIT:C25444 @@ -12228,7 +12240,7 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "embryonic notocord" EXACT [] -synonym: "notochorda" RELATED LATIN [Wikipedia:Notochord] +synonym: "notochorda" RELATED OMO:0003011 [Wikipedia:Notochord] synonym: "notocord" EXACT [ZFA:0000135] xref: AAO:0000327 xref: BTO:0001768 @@ -12287,7 +12299,7 @@ synonym: "epithelial somite" RELATED [https://github.com/obophenotype/uberon/wik synonym: "mesodermal cluster" BROAD [GO:0001756] synonym: "somites" RELATED OMO:0003004 [] synonym: "somitic mesoderm" RELATED [] -synonym: "somitus" RELATED LATIN [Wikipedia:Somite] +synonym: "somitus" RELATED OMO:0003011 [Wikipedia:Somite] xref: AAO:0010569 xref: AEO:0001015 xref: BTO:0001558 @@ -12331,7 +12343,7 @@ comment: Gene notes: Many factors and genes, such as Pax3 (Tremblay et al., 1995 subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "crista neuralis" RELATED LATIN [Wikipedia:Neural_crest] +synonym: "crista neuralis" RELATED OMO:0003011 [Wikipedia:Neural_crest] synonym: "NC" EXACT OMO:0003000 [XAO:0000048] synonym: "neural crest material" RELATED [VHOG:0000057] xref: AAO:0010578 @@ -12377,7 +12389,7 @@ namespace: uberon def: "Embryonic ectoderm that gives rise to nervous tissue." [Wikipedia:Neuroectoderm] subset: uberon_slim subset: vertebrate_core -synonym: "epithelium tubi neuralis; neuroectoderma" RELATED LATIN [Wikipedia:Neuroectoderm] +synonym: "epithelium tubi neuralis; neuroectoderma" RELATED OMO:0003011 [Wikipedia:Neuroectoderm] synonym: "neuaral ectoderm" RELATED [] synonym: "neural ectoderm" EXACT [] synonym: "neuroectoderm" EXACT [] @@ -12391,7 +12403,7 @@ xref: EHDAA:1498 xref: EHDAA:255 xref: EMAPA:16073 xref: EV:0100004 -xref: FBbt:00001057 +xref: FBbt:00001057 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:87657 xref: MAT:0000176 xref: MIAA:0000176 @@ -12543,7 +12555,7 @@ subset: pheno_slim synonym: "epithelial tissue of iris" EXACT [OBOL:automatic] synonym: "epithelium of iris" EXACT [OBOL:automatic] synonym: "epithelium pigmentosum (iris)" EXACT [FMA:58517] -synonym: "epithelium pigmentosum iridis" EXACT LATIN [FMA:58517, FMA:TA] +synonym: "epithelium pigmentosum iridis" EXACT OMO:0003011 [FMA:58517, FMA:TA] synonym: "iris epithelial tissue" EXACT [OBOL:automatic] synonym: "iris epithelium" EXACT [FMA:58517] synonym: "iris pigmented epithelium" RELATED [MA:0002826] @@ -12572,7 +12584,7 @@ subset: vertebrate_core synonym: "blastocyst" RELATED [] synonym: "ectoblast" RELATED [MP:0003886] synonym: "epiblast" EXACT [VHOG:0000243] -synonym: "epiblastus" RELATED LATIN [Wikipedia:Epiblast] +synonym: "epiblastus" RELATED OMO:0003011 [Wikipedia:Epiblast] synonym: "primitive ectoderm" RELATED [VHOG:0000243] xref: BTO:0004593 xref: FMA:296704 @@ -12883,7 +12895,7 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "lens placodes" RELATED OMO:0003004 [ZFA:0000122] -synonym: "placoda lentis" RELATED LATIN [Wikipedia:Lens_placode] +synonym: "placoda lentis" RELATED OMO:0003011 [Wikipedia:Lens_placode] xref: AAO:0011055 xref: EFO:0003494 xref: EHDAA2:0000982 @@ -12918,7 +12930,7 @@ def: "A region of embryonic ectodermal cells that lie directly above the notocho subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "lamina neuralis" RELATED LATIN [Wikipedia:Neural_plate] +synonym: "lamina neuralis" RELATED OMO:0003011 [Wikipedia:Neural_plate] synonym: "presumptive central nervous system" RELATED [] xref: AAO:0011072 xref: BTO:0001765 @@ -12928,7 +12940,7 @@ xref: EHDAA:346 xref: EHDAA:902 xref: EMAPA:35593 xref: FMA:293879 -xref: MESH:D054258 +xref: MESH:D054258 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: NCIT:C34225 xref: neuronames:1362 xref: RETIRED_EHDAA2:0001252 @@ -12971,7 +12983,7 @@ def: "The paraxial mesoderm is the mesoderm located bilaterally adjacent to the subset: efo_slim subset: uberon_slim subset: vertebrate_core -synonym: "mesoderma paraxiale" RELATED LATIN [Wikipedia:Paraxial_mesoderm] +synonym: "mesoderma paraxiale" RELATED OMO:0003011 [Wikipedia:Paraxial_mesoderm] synonym: "paraxial mesenchyme" EXACT [https://github.com/obophenotype/uberon/issues/30, https://github.com/obophenotype/uberon/wiki/The-neural-crest, ZFA:0000255] synonym: "somitic mesoderm" EXACT [ISBN:9780878932504] xref: AAO:0010568 @@ -13025,7 +13037,7 @@ synonym: "lateral mesoderm" EXACT [GO:0048368] synonym: "lateral plate" RELATED [] synonym: "lateral plate mesenchyme" RELATED [EHDAA2:0000919] synonym: "LPM" EXACT OMO:0003000 [ZFA:0000121] -synonym: "mesoderma laminae lateralis" RELATED LATIN [Wikipedia:Lateral_plate_mesoderm] +synonym: "mesoderma laminae lateralis" RELATED OMO:0003011 [Wikipedia:Lateral_plate_mesoderm] xref: AAO:0010574 xref: EHDAA2:0000919 xref: EHDAA:379 @@ -13086,10 +13098,10 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "sclerotomes" EXACT OMO:0003004 [TAO:0001080] -synonym: "sclerotomus" RELATED LATIN [Wikipedia:Sclerotome] +synonym: "sclerotomus" RELATED OMO:0003011 [Wikipedia:Sclerotome] xref: AAO:0010571 xref: AEO:0000212 -xref: BTO:0006255 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: BTO:0006255 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: EHDAA2:0003439 xref: EMAPA:31159 xref: FMA:295652 @@ -13118,7 +13130,7 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "optic stalks" RELATED OMO:0003004 [ZFA:0000137] -synonym: "pedunculus opticus" RELATED LATIN [Wikipedia:Optic_stalk] +synonym: "pedunculus opticus" RELATED OMO:0003011 [Wikipedia:Optic_stalk] xref: AAO:0011077 xref: EHDAA2:0001318 xref: EHDAA:3816 @@ -13150,7 +13162,7 @@ subset: vertebrate_core synonym: "cephalic neural crest" EXACT [EMAPA:16091] synonym: "CNC" EXACT OMO:0003000 [XAO:0001001] synonym: "cranial NCC population" EXACT [] -synonym: "crista neuralis cranialis" RELATED LATIN [Wikipedia:Cranial_neural_crest] +synonym: "crista neuralis cranialis" RELATED OMO:0003011 [Wikipedia:Cranial_neural_crest] synonym: "head crest" RELATED [] synonym: "head NCC population" EXACT [] synonym: "head neural crest" RELATED [] @@ -13201,7 +13213,7 @@ def: "Portion of tissue composed of mesenchymal cells (motile cells that develop subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "mesenchyma" RELATED LATIN [Wikipedia:Mesenchyme] +synonym: "mesenchyma" RELATED OMO:0003011 [Wikipedia:Mesenchyme] synonym: "mesenchymal tissue" EXACT [] synonym: "mesenchyme tissue" EXACT [] synonym: "portion of mesenchymal tissue" EXACT [] @@ -13512,7 +13524,7 @@ synonym: "neural retina" EXACT [XAO:0003216, ZFA:0000046] synonym: "neural retinal epithelium" RELATED [MA:000027] synonym: "neuroretina" EXACT [ZFA:0000046] synonym: "stratum nervosum (retina)" EXACT [FMA:58628] -synonym: "stratum nervosum retinae" EXACT LATIN [FMA:58628, FMA:TA] +synonym: "stratum nervosum retinae" EXACT OMO:0003011 [FMA:58628, FMA:TA] xref: AAO:0011095 xref: BTO:0000929 xref: CALOHA:TS-0685 @@ -13546,7 +13558,7 @@ def: "Epithelial tubes transport gases, liquids and cells from one site to anoth synonym: "epithelial or endothelial tube" EXACT [] xref: AEO:0000114 xref: EHDAA2:0003114 -xref: FBbt:00007474 +xref: FBbt:00007474 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0000025 ! tube is_a: UBERON:0000483 ! epithelium intersection_of: UBERON:0000483 ! epithelium @@ -13913,7 +13925,7 @@ subset: vertebrate_core synonym: "Descemet membrane" EXACT [] synonym: "Descemet's posterior elastic lamina" EXACT [FMA:58309] synonym: "lamina limitans posterior" EXACT [FMA:58309] -synonym: "lamina limitans posterior corneae" EXACT LATIN [FMA:58309, FMA:TA] +synonym: "lamina limitans posterior corneae" EXACT OMO:0003011 [FMA:58309, FMA:TA] synonym: "posterior limiting lamina" EXACT [MA:0001246] synonym: "posterior limiting lamina of cornea" EXACT [FMA:58309] synonym: "posterior limiting membrane" EXACT [ZFA:0001686] @@ -13957,8 +13969,8 @@ synonym: "Bowman's anterior elastic lamina" EXACT [FMA:58273] synonym: "Bowman's layer" EXACT [FMA:58273] synonym: "Bowman's membrane" EXACT [FMA:58273] synonym: "lamina limitans anterior (cornea)" EXACT [FMA:58273] -synonym: "lamina limitans anterior corneae" EXACT LATIN [FMA:58273, FMA:TA] -synonym: "Reichert's membrane" RELATED DUBIOUS [http://sourceforge.net/tracker/?func=detail&aid=2956371&group_id=76834&atid=974957] +synonym: "lamina limitans anterior corneae" EXACT OMO:0003011 [FMA:58273, FMA:TA] +synonym: "Reichert's membrane" RELATED OMO:0003002 [http://sourceforge.net/tracker/?func=detail&aid=2956371&group_id=76834&atid=974957] xref: FMA:58273 xref: MA:0001240 xref: NCIT:C32226 @@ -14066,6 +14078,7 @@ id: UBERON:0004638 name: blood vessel endothelium namespace: uberon def: "An endothelium that lines the blood vasculature. Other endothelia may line lymph vessels, the heart." [https://orcid.org/0000-0002-6601-2165] +subset: human_reference_atlas subset: pheno_slim subset: vertebrate_core xref: BTO:0000766 @@ -14080,6 +14093,7 @@ is_a: UBERON:0004852 ! cardiovascular system endothelium intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:0001981 ! blood vessel relationship: part_of UBERON:0001981 ! blood vessel +relationship: present_in_taxon NCBITaxon:9606 [Term] id: UBERON:0004716 @@ -14148,7 +14162,7 @@ synonym: "trilaminar disk" RELATED [https://orcid.org/0000-0002-6601-2165] synonym: "trilaminar germ" RELATED [https://orcid.org/0000-0002-6601-2165] xref: BILA:0000060 xref: BTO:0001403 -xref: FBbt:00005317 +xref: FBbt:00005317 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:293108 xref: GAID:1302 xref: MESH:D005775 @@ -14279,7 +14293,7 @@ namespace: uberon def: "Anatomical structure that connects two or more adjacent skeletal elements or hardened body parts." [http://orcid.org/0000-0002-6601-2165] subset: grouping_class synonym: "joint" NARROW [] -xref: FBbt:00005811 +xref: FBbt:00005811 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0034921 ! multi organ part structure relationship: part_of UBERON:0004770 ! articular system @@ -14295,7 +14309,7 @@ synonym: "gut section" RELATED [FBbt:00100315] synonym: "intestinal tract" RELATED [] synonym: "segment of intestinal tract" RELATED [] synonym: "subdivision of alimentary system" RELATED [FMA:71131] -xref: FBbt:00100315 +xref: FBbt:00100315 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:71131 is_a: UBERON:0013522 ! subdivision of tube intersection_of: UBERON:0013522 ! subdivision of tube @@ -14418,7 +14432,7 @@ synonym: "multi-cell-component structure" EXACT [CARO:0001000] synonym: "multi-cell-part structure" EXACT [CARO:0001000] xref: AAO:0011000 xref: CARO:0001000 -xref: FBbt:00007060 +xref: FBbt:00007060 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:83115 is_a: UBERON:0000061 ! anatomical structure relationship: composed_primarily_of GO:0005575 ! cellular_component @@ -14551,7 +14565,7 @@ xref: EHDAA:5526 xref: EMAPA:17082 xref: HBA:9512 xref: MA:0000205 -xref: MESH:D054024 +xref: MESH:D054024 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: VHOG:0000456 xref: Wikipedia:Myelencephalon is_a: UBERON:0004121 ! ectoderm-derived structure @@ -14584,7 +14598,7 @@ name: photoreceptor array namespace: uberon def: "An array of photoreceptors and any supporting cells found in an eye." [https://orcid.org/0000-0002-6601-2165] synonym: "light-sensitive tissue" EXACT [] -xref: FBbt:00004200 +xref: FBbt:00004200 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0004923 ! organ component layer intersection_of: UBERON:0004923 ! organ component layer intersection_of: composed_primarily_of CL:0000210 ! photoreceptor cell @@ -14616,7 +14630,7 @@ synonym: "developmental tissue" RELATED [MIAA:0000019] xref: AEO:0000125 xref: CALOHA:TS-2122 xref: EHDAA2:0003125 -xref: FBbt:00007006 +xref: FBbt:00007006 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:292313 xref: MIAA:0000019 is_a: UBERON:0000465 ! material anatomical entity @@ -14724,7 +14738,7 @@ def: "Multi-tissue structure that arises from the heart rudiment and will become subset: vertebrate_core synonym: "early primitive heart tube" NARROW [EMAPA:16208] synonym: "primitive heart tube" EXACT [EMAPA:16215] -xref: BTO:0006179 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: BTO:0006179 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: EHDAA2:0001512 xref: EHDAA:424 xref: EHDAA:436 @@ -14776,7 +14790,7 @@ namespace: uberon def: "An acellular membrane that is part of the epithelium, lies adjacent to the epithelial cells, and is the fusion of the the basal lamina and the reticular lamina." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Basement_membrane] synonym: "basement membrane" RELATED [FMA:63872] synonym: "basement membrane of connective tissue" EXACT [FMA:63872] -synonym: "membrana basalis" EXACT LATIN [Wikipedia:Basement_membrane] +synonym: "membrana basalis" EXACT OMO:0003011 [Wikipedia:Basement_membrane] xref: AAO:0010596 xref: FMA:63872 xref: GAID:915 @@ -14843,7 +14857,7 @@ def: "Subdivision of skeleton which consists of cranial skeleton, set of all ver subset: human_reference_atlas subset: pheno_slim subset: uberon_slim -synonym: "skeleton axiale" RELATED LATIN [Wikipedia:Axial_skeleton] +synonym: "skeleton axiale" RELATED OMO:0003011 [Wikipedia:Axial_skeleton] xref: AAO:0000963 xref: EMAPA:17214 xref: EMAPA:18043 @@ -14871,8 +14885,8 @@ def: "A threadlike extension of a nerve cell and consists of an axon and myelin subset: human_reference_atlas synonym: "nerve fibers" RELATED OMO:0003004 [BAMS:nfi] synonym: "nerve fibre" EXACT [FMA:5914] -synonym: "neurofibra" EXACT LATIN [FMA:5914, FMA:TA] -synonym: "neurofibra" RELATED LATIN [Wikipedia:Nerve_fiber] +synonym: "neurofibra" EXACT OMO:0003011 [FMA:5914, FMA:TA] +synonym: "neurofibra" RELATED OMO:0003011 [Wikipedia:Nerve_fiber] synonym: "neurofibrum" EXACT [FMA:5914] xref: BAMS:nfi xref: FMA:5914 @@ -15620,7 +15634,7 @@ synonym: "organ field" RELATED [] xref: AEO:0000170 xref: EFO:0001649 xref: EHDAA2:0003170 -xref: FBbt:00005426 +xref: FBbt:00005426 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: Wikipedia:Anlage_(biology) is_a: UBERON:0000479 {source="FBbt"} ! tissue is_a: UBERON:0005423 {source="AEO", source="FBbt"} ! developing anatomical structure @@ -15824,7 +15838,7 @@ subset: common_anatomy subset: upper_level synonym: "multicellular structure" EXACT [FBbt:00100313] xref: CARO:0010000 -xref: FBbt:00100313 +xref: FBbt:00100313 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0000061 ! anatomical structure intersection_of: UBERON:0000061 ! anatomical structure intersection_of: has_quality PATO:0001993 ! multicellular @@ -15990,8 +16004,8 @@ def: "The ciliary processes are formed by the inward folding of the various laye synonym: "ciliary process" RELATED [Wikipedia:Ciliary_processes] synonym: "ciliary processes" EXACT [FMA:76551] synonym: "ciliary processes set" EXACT [FMA:76551] -synonym: "processus ciliares" EXACT LATIN [FMA:TA] -synonym: "processus ciliares" RELATED LATIN [Wikipedia:Ciliary_processes] +synonym: "processus ciliares" EXACT OMO:0003011 [FMA:TA] +synonym: "processus ciliares" RELATED OMO:0003011 [Wikipedia:Ciliary_processes] synonym: "set of ciliary processes" EXACT [FMA:76551] xref: FMA:76551 xref: SCTID:280860001 @@ -16062,8 +16076,9 @@ name: organ system subdivision namespace: uberon def: "A subdivision of an anatomical system." [http://orcid.org/0000-0002-6601-2165] subset: common_anatomy +subset: human_reference_atlas subset: upper_level -xref: FBbt:00007330 +xref: FBbt:00007330 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:67509 xref: SCTID:91690000 is_a: UBERON:0010000 {source="FBbt"} ! multicellular anatomical structure @@ -16071,6 +16086,7 @@ relationship: part_of UBERON:0000467 ! anatomical system relationship: present_in_taxon NCBITaxon:33090 relationship: present_in_taxon NCBITaxon:33208 ! Metazoa relationship: present_in_taxon NCBITaxon:4751 +relationship: present_in_taxon NCBITaxon:9606 [Term] id: UBERON:0011222 @@ -16156,8 +16172,8 @@ id: UBERON:0011825 name: loose connective tissue namespace: uberon def: "Irregular connective tissue, the intercellular matrix of which contains a sparse irregular network of collagen and elastic fiber bundles. Examples: areolar tissue, neuroglial tissue, mucoid tissue." [FMA:19783] -synonym: "textus connectivus collagenosus laxus" EXACT LATIN [FMA:19783, FMA:TA] -synonym: "textus connectivus laxus" EXACT LATIN [FMA:19783, FMA:TA] +synonym: "textus connectivus collagenosus laxus" EXACT OMO:0003011 [FMA:19783, FMA:TA] +synonym: "textus connectivus laxus" EXACT OMO:0003011 [FMA:19783, FMA:TA] xref: FMA:19783 xref: NCIT:C33007 xref: UMLS:C1253917 {source="ncithesaurus:Loose_Connective_Tissue"} @@ -16290,7 +16306,6 @@ id: UBERON:0013702 name: body proper namespace: uberon def: "The region of the organism associated with the visceral organs." [AEO:0000103] -subset: human_reference_atlas subset: non_informative synonym: "body" RELATED [AEO:0000103] synonym: "whole body" RELATED [BTO:0001489] @@ -16300,7 +16315,6 @@ xref: EMAPA:36031 xref: FMA:231424 is_a: UBERON:0000475 {source="AEO"} ! organism subdivision relationship: part_of UBERON:0013701 ! main body axis -relationship: present_in_taxon NCBITaxon:9606 property_value: UBPROP:0000001 "Cardinal body part, which consists of a maximal set of diverse subclasses of organ and organ part spatially associated with the vertebral column and ribcage. Examples: There is only one body proper[FMA:231424]." xsd:string {source="FMA:231424"} [Term] @@ -16341,7 +16355,7 @@ name: non-connected functional system namespace: uberon def: "An anatomical group whose component structures share a common function." [AEO:0000093, AEO:JB, FBbt:00007278, FBC:DOS] xref: AEO:0000093 -xref: FBbt:00007278 +xref: FBbt:00007278 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0034923 ! disconnected anatomical group [Term] @@ -16581,7 +16595,7 @@ namespace: uberon def: "Material anatomical entity consisting of multiple anatomical structures that are not connected to each other." [CARO:0020000] subset: common_anatomy xref: CARO:0020000 -xref: FBbt:00007276 +xref: FBbt:00007276 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0000465 {source="CARO"} ! material anatomical entity relationship: composed_primarily_of UBERON:0000061 ! anatomical structure relationship: has_component UBERON:0000061 {minCardinality="2"} ! anatomical structure @@ -16611,13 +16625,13 @@ def: "The parts of the orbital region that are outside of the the eyeball, inclu synonym: "accessory parts of orbital region" RELATED [] synonym: "accessory visual structures" RELATED [FMA:76554, Wikipedia:Accessory_visual_structures] synonym: "accessory visual structures set" RELATED [FMA:76554] -synonym: "adnexa oculi" EXACT LATIN [http://medical-dictionary.thefreedictionary.com/ocular+adnexa] +synonym: "adnexa oculi" EXACT OMO:0003011 [http://medical-dictionary.thefreedictionary.com/ocular+adnexa] synonym: "adnexal parts of orbital region" RELATED [] synonym: "appendage of eye" RELATED [http://medical-dictionary.thefreedictionary.com/ocular+adnexa] synonym: "appendages of the eye" RELATED OMO:0003004 [http://medical-dictionary.thefreedictionary.com/ocular+adnexa] synonym: "eye adnexa" RELATED [] synonym: "set of accessory visual structures" RELATED [FMA:76554] -synonym: "structurae oculi accessoriae" RELATED LATIN [Wikipedia:Accessory_visual_structures] +synonym: "structurae oculi accessoriae" RELATED OMO:0003011 [Wikipedia:Accessory_visual_structures] xref: FMA:76554 xref: NCIT:C32574 xref: SCTID:120612006 @@ -17056,20 +17070,6 @@ property_value: seeAlso "https://github.com/obophenotype/uberon/wiki/Part-disjoi is_a: RO:0002323 ! mereotopologically related to expand_expression_to: "BFO_0000051 exactly 0 (BFO_0000050 some ?Y)" [] -[Typedef] -id: RO:0002203 -name: develops into -def: "inverse of develops from" [] -subset: RO:0002259 -property_value: IAO:0000114 IAO:0000125 -property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 -property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172 -property_value: IAO:0000117 https://orcid.org/0000-0003-1980-3228 -is_transitive: true -is_a: has_potential_to_develop_into ! has potential to develop into -is_a: RO:0002286 ! developmentally succeeded by -is_a: RO:0002388 ! has potential to directly develop into - [Typedef] id: RO:0002206 name: expressed in @@ -17090,7 +17090,7 @@ def: "inverse of directly develops from" [] subset: RO:0002259 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000118 "developmental precursor of" xsd:string -is_a: RO:0002203 ! develops into +is_a: develops_into ! develops into [Typedef] id: RO:0002222 @@ -17120,7 +17120,7 @@ def: "inverse of has developmental contribution from" [] subset: RO:0002259 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 -holds_over_chain: RO:0002203 part_of +holds_over_chain: develops_into part_of is_a: has_potential_to_developmentally_contribute_to ! has potential to developmentally contribute to is_a: RO:0002286 ! developmentally succeeded by @@ -18406,7 +18406,7 @@ range: BFO:0000004 ! independent continuant is_transitive: true is_a: has_developmental_contribution_from ! has developmental contribution from is_a: RO:0002258 ! developmentally preceded by -inverse_of: RO:0002203 ! develops into +inverse_of: develops_into ! develops into [Typedef] id: develops_from_part_of @@ -18433,6 +18433,22 @@ domain: UBERON:0001062 ! anatomical entity holds_over_chain: directly_develops_from located_in is_a: RO:0002258 ! developmentally preceded by +[Typedef] +id: develops_into +name: develops into +namespace: uberon +def: "inverse of develops from" [] +subset: RO:0002259 +xref: RO:0002203 +property_value: IAO:0000114 IAO:0000125 +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 +property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172 +property_value: IAO:0000117 https://orcid.org/0000-0003-1980-3228 +is_transitive: true +is_a: has_potential_to_develop_into ! has potential to develop into +is_a: RO:0002286 ! developmentally succeeded by +is_a: RO:0002388 ! has potential to directly develop into + [Typedef] id: directly_develops_from name: directly develops from @@ -18767,7 +18783,7 @@ is_a: RO:0002479 ! has part that occurs in id: has_high_plasma_membrane_amount name: obsolete has_high_plasma_membrane_amount def: "OBSOLETE A relation between a cell and molecule or complex such that every instance of the cell has a high number of instances of that molecule expressed on the cell surface. For the formal definition, see Masci et al (PMID:19243617)." [PMID:19243617] -comment: Replaced with RO:0015015, see https://github.com/obophenotype/cell-ontology/issues/1481 +property_value: term_tracker_item https://github.com/obophenotype/cell-ontology/issues/1481 is_obsolete: true replaced_by: RO:0015015 @@ -18794,7 +18810,7 @@ inverse_of: input_of ! input of id: has_low_plasma_membrane_amount name: obsolete has_low_plasma_membrane_amount def: "OBSOLETE A relation between a cell and molecule or complex such that every instance of the cell has a low number of instances of that molecule expressed on the cell surface. For the formal definition, see Masci et al (PMID:19243617)." [PMID:19243617] -comment: Replaced with RO:0015016, see https://github.com/obophenotype/cell-ontology/issues/1481 +property_value: term_tracker_item https://github.com/obophenotype/cell-ontology/issues/1481 is_obsolete: true replaced_by: RO:0015016 @@ -20183,21 +20199,21 @@ is_a: develops_from ! develops from id: transitively_anteriorly_connected_to name: transitively anteriorly connected to namespace: uberon -def: "." [http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern] +property_value: seeAlso "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" xsd:anyURI is_transitive: true [Typedef] id: transitively_distally_connected_to name: transitively distally connected to namespace: uberon -def: "." [http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern] +property_value: seeAlso "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" xsd:anyURI is_transitive: true [Typedef] id: transitively_proximally_connected_to name: transitively proximally connected to namespace: uberon -def: "." [http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern] +property_value: seeAlso "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" xsd:anyURI is_transitive: true [Typedef] diff --git a/src/ontology/subsets/eye_upper_slim.owl b/src/ontology/subsets/eye_upper_slim.owl index fec82a604..379bb2999 100644 --- a/src/ontology/subsets/eye_upper_slim.owl +++ b/src/ontology/subsets/eye_upper_slim.owl @@ -18,6 +18,7 @@ xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#" xmlns:skos="http://www.w3.org/2004/02/skos/core#" xmlns:swrl="http://www.w3.org/2003/11/swrl#" + xmlns:sssom="https://w3id.org/sssom/" xmlns:swrla="http://swrl.stanford.edu/ontologies/3.3/swrla.owl#" xmlns:swrlb="http://www.w3.org/2003/11/swrlb#" xmlns:terms="http://purl.org/dc/terms/" @@ -29,8 +30,8 @@ xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#" xmlns:ncbitaxon="http://purl.obolibrary.org/obo/ncbitaxon#"> - - 2024-01-04 + + 2024-02-13 @@ -315,6 +316,14 @@ Annotations: IAO_0000424 "http://purl.obolibrary.org/obo/BFO_0000051 some ( + + + + + + + + @@ -337,6 +346,14 @@ Annotations: IAO_0000424 "http://purl.obolibrary.org/obo/BFO_0000051 some ( + + + + + + + + @@ -846,25 +863,25 @@ WHERE { - + - + - + - + - + - + @@ -1071,14 +1088,6 @@ WHERE { - - - - - - - - @@ -1103,14 +1112,6 @@ WHERE { - - - - - - - - @@ -1942,6 +1943,24 @@ WHERE { + + + + + + + + + + + + + + + + + + - - - - - - - - - - - - - - - - - - - - - A nucleus size quality which is relatively high compared to the amount of cytoplasm present in the same cell. - - 2009-12-23T10:53:24Z - increased nucleus size - - - - - A nucleus size quality which is relatively high compared to the amount of cytoplasm present in the same cell. - GOC:tfm - - - - @@ -13758,6 +13803,7 @@ plexiform layer. An epithelial cell that is part of the conjunctiva. FMA:70552 epithelial cell of conjunctiva + conjunctival epithelial cell @@ -13806,6 +13852,7 @@ plexiform layer. A smooth muscle cell that is part of the ciliary body. FMA:70610 smooth muscle cell of ciliary body + ciliary muscle cell @@ -14718,7 +14765,7 @@ plexiform layer. - A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex). + A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex). https://github.com/geneontology/go-ontology/issues/17729 GO:0008372 NIF_Subcellular:sao1337158144 @@ -14739,7 +14786,7 @@ plexiform layer. - A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex). + A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex). GOC:pdt @@ -14769,8 +14816,8 @@ plexiform layer. + - Note that this term is intended to annotate gene products that are not attached to the cell surface. For gene products from multicellular organisms which are secreted from a cell but retained within the organism (i.e. released into the interstitial fluid or blood), consider the cellular component term 'extracellular space ; GO:0005615'. extracellular region @@ -14815,32 +14862,32 @@ plexiform layer. - - + + A protein complex consisting of three collagen chains assembled into a left-handed triple helix. These trimers typically assemble into higher order structures. Wikipedia:Collagen cellular_component GO:0005581 collagen trimer - + - + - + PMID:12382326 - + PMID:12382326 @@ -14922,7 +14969,7 @@ plexiform layer. - + Note that for multicellular organisms, the extracellular space refers to everything outside a cell, but still within the organism (excluding the extracellular matrix). Gene products from a multi-cellular organism that are secreted from a cell into the interstitial fluid or blood can therefore be annotated to this term. extracellular space @@ -15062,8 +15109,8 @@ plexiform layer. + - Chromosomes include parts that are not part of the chromatin. Examples include the kinetochore. chromosome @@ -15129,8 +15176,8 @@ plexiform layer. + - cytoplasm @@ -15168,8 +15215,8 @@ plexiform layer. + - ribosome @@ -15228,8 +15275,8 @@ plexiform layer. + - plasma membrane @@ -15336,7 +15383,7 @@ plexiform layer. - + translation @@ -15464,7 +15511,7 @@ plexiform layer. - + Note that this term should not be used for direct annotation. It should be possible to make a more specific annotation to one of the children of this term, for e.g. to transmembrane transport, to microtubule-based transport or to vesicle-mediated transport. transport @@ -16486,7 +16533,7 @@ plexiform layer. necrosis GO:0008219 - This term should not be used for direct annotation, it is currently kept in GO as a placeholder for describing cell death phenotypes in uPHENO. When information is provided on a programmed cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'). Unintentional cell death, i.e. cell death caused by injury, ageing, or cell phenotypes observed as a result of a pathological mutation in an essential gene should NOT be annotated using GO terms. + This term should not be used for direct annotation, it is currently kept in GO as a placeholder for describing cell death phenotypes in uPHENO. When information is provided on a programmed cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'). Unintentional cell death, i.e. cell death caused by injury, ageing, or cell phenotypes observed as a result of a pathological mutation in an essential gene should NOT be annotated using GO terms. cell death @@ -17022,7 +17069,7 @@ plexiform layer. - + Note that this term should be used to annotate gene products in the organism undergoing the programmed cell death. To annotate genes in another organism whose products modulate programmed cell death in a host organism, consider the term 'modulation by symbiont of host programmed cell death ; GO:0052040'. Also, note that 'programmed cell death ; GO:0012501' should be used to refer to instances of caspase-independent cell death mechanisms, in the absence of further indications on the process taking place. At present, caspase-independent cell death is not yet represented in GO due to the lack of consensus and in-depth research on the topic. 'programmed cell death ; GO:0012501' may also be used to annotate gene products in taxa where apoptosis as defined in GO:0006915 does not occur, such as plants. You may also consider these specific children: GO:0097468 'programmed cell death in response to reactive oxygen species' (with descendants GO:0010421 'hydrogen peroxide-mediated programmed cell death' and GO:0010343 'singlet oxygen-mediated programmed cell death'), and GO:0009626 'plant-type hypersensitive response' and its children. programmed cell death @@ -17758,8 +17805,8 @@ plexiform layer. + - Note that a signal is any variable property or parameter that serves to convey information, and may be a physical entity such as a gene product or small molecule, a photon, or a change in state such as movement or voltage change. signaling @@ -17851,7 +17898,7 @@ plexiform layer. cell projection organization and biogenesis cell surface structure organization and biogenesis GO:0030030 - + cell projection organization @@ -18373,7 +18420,7 @@ plexiform layer. - + extracellular matrix @@ -19230,7 +19277,7 @@ plexiform layer. - + cell projection @@ -19375,6 +19422,7 @@ plexiform layer. The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. + https://github.com/geneontology/go-ontology/issues/26424 GO:0034960 GO:0043283 GO:0044259 @@ -19384,6 +19432,7 @@ plexiform layer. multicellular organismal macromolecule metabolic process biological_process GO:0043170 + macromolecule metabolic process @@ -19471,7 +19520,7 @@ plexiform layer. - + organelle @@ -19964,9 +20013,11 @@ plexiform layer. The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism. + https://github.com/geneontology/go-ontology/issues/26424 primary metabolism biological_process GO:0044238 + primary metabolic process @@ -20543,9 +20594,11 @@ plexiform layer. The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. + https://github.com/geneontology/go-ontology/issues/26424 development of an anatomical structure biological_process GO:0048856 + @@ -20593,7 +20646,7 @@ plexiform layer. - + cell motility @@ -20804,7 +20857,7 @@ plexiform layer. - + Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. response to stimulus @@ -21672,7 +21725,7 @@ plexiform layer. - + protein-containing complex assembly @@ -21890,6 +21943,7 @@ plexiform layer. The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon. + https://github.com/geneontology/go-ontology/issues/26424 mah 2010-03-08T03:32:18Z organic molecular entity metabolic process @@ -21897,6 +21951,7 @@ plexiform layer. organic substance metabolism biological_process GO:0071704 + organic substance metabolic process @@ -22010,7 +22065,7 @@ plexiform layer. - The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures. + The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures. mah 2010-10-04T01:51:47Z cellular_component @@ -22021,7 +22076,7 @@ plexiform layer. - The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures. + The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures. GOC:pdt @@ -22929,6 +22984,7 @@ plexiform layer. A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex but below that of an anatomical system. Or, a substance produced by a cellular organism with granularity above the level of a protein complex. https://github.com/geneontology/go-ontology/issues/24200 + https://github.com/geneontology/go-ontology/issues/26424 kmv 2019-08-12T18:01:37Z cellular_component @@ -24213,57 +24269,6 @@ plexiform layer. - - - - - quality - PATO:0000068 - TODO: define this or obsolete it and move children somewhere else. - qualitative - - - - - - - - - A quality inhering in a bearer by virtue of the whether the bearer differs from normal or average. - quality - PATO:0000069 - - deviation (from_normal) - - - - - A quality inhering in a bearer by virtue of the whether the bearer differs from normal or average. - PATOC:GVG - - - - - - - - - A morphology quality inhering in a bearer by virtue of the bearer's physical magnitude. - quality - PATO:0000117 - - - size - - - - - A morphology quality inhering in a bearer by virtue of the bearer's physical magnitude. - WordNet:WordNet - - - - @@ -24359,67 +24364,6 @@ plexiform layer. - - - - - A quality inhering in a bearer by virtue of the bearer's exhibiting no deviation from normal or average. - - quality - average - PATO:0000461 - - - - normal - - - - - A quality inhering in a bearer by virtue of the bearer's exhibiting no deviation from normal or average. - PATOC:GVG - - - - - - - - - - - - - - - - - - - - - A size quality which is relatively high. - - PATO:0001202 - quality - big - enlarged - expanded - great - large - PATO:0000586 - - increased size - - - - - A size quality which is relatively high. - PATOC:GVG - - - - @@ -25239,77 +25183,6 @@ plexiform layer. - - - - - - - - - - - - - - - - - - - - - - A quality that has a value that is increased compared to normal or average. - - - 2011-06-16T06:39:43Z - quality - PATO:0002300 - increased quality - - - - - A quality that has a value that is increased compared to normal or average. - PATOC:GVG - - - - - - - - - - - - - - - - - - - - - A quality of an object that has a value that is increased compared to normal or average. - - - 2011-06-16T06:54:01Z - quality - PATO:0002305 - increased object quality - - - - - A quality of an object that has a value that is increased compared to normal or average. - PATOC:GVG - - - - @@ -25461,6 +25334,28 @@ plexiform layer. + + + + + A quality inhering in a cell by virtue of the cell having a high nuclear/cytoplasmic ratio. + http://orcid.org/0000-0001-5208-3432 + high N:C ratio + quality + PATO:0040072 + A high nuclear/cytolasmic ratio is 70% or higher. + high nuclear/cytoplasmic ratio + + + + + A quality inhering in a cell by virtue of the cell having a high nuclear/cytoplasmic ratio. + Wikipedia:NC_ratio&oldid=931936284 + http://lymerick.net/blood-cells.pdf + + + + @@ -26727,7 +26622,7 @@ plexiform layer. - + @@ -26768,14 +26663,14 @@ plexiform layer. camera-type eye - + - + definitional @@ -26835,7 +26730,7 @@ plexiform layer. regio orbitalis FMA:54448 FMA:TA - + @@ -26927,6 +26822,12 @@ plexiform layer. https://github.com/obophenotype/uberon/issues/549 https://orcid.org/0000-0002-6601-2165 + + + + FBbt:00005155 + + @@ -27234,7 +27135,7 @@ plexiform layer. tunica serosa FMA:9581 - + @@ -27406,6 +27307,12 @@ plexiform layer. Material anatomical entity that is a single connected structure with inherent 3D shape generated by coordinated expression of the organism's own genome. CARO:0000003 + + + + FBbt:00007001 + + @@ -27874,7 +27781,7 @@ plexiform layer. - + The surface (external) layer of ectoderm which begins to proliferate shortly after separation from the neuroectoderm. merge with non-neural. In vertebrates, the ectoderm has three parts: external ectoderm (also known as surface ectoderm), the neurectoderm (neural crest, and neural tube) @@ -27900,7 +27807,7 @@ plexiform layer. external ectoderm http://upload.wikimedia.org/wikipedia/commons/1/1d/Ectoderm.png - + @@ -27913,7 +27820,7 @@ plexiform layer. - + EHDAA2 @@ -27927,7 +27834,9 @@ plexiform layer. BTO:0006242 - https://orcid.org/0000-0003-4423-4370 + + + https://github.com/biopragmatics/biomappings @@ -28146,7 +28055,9 @@ plexiform layer. IDOMAL:0000302 - https://orcid.org/0000-0003-4423-4370 + + + https://github.com/biopragmatics/biomappings @@ -28171,7 +28082,7 @@ plexiform layer. zygotum Wikipedia:Zygote - + @@ -28295,7 +28206,7 @@ plexiform layer. - + @@ -28331,14 +28242,14 @@ plexiform layer. gastrula stage - + - + BILS @@ -28521,6 +28432,12 @@ plexiform layer. FBC:DOS FBbt:00005099 + + + + FBbt:00005099 + + @@ -28708,6 +28625,12 @@ plexiform layer. in FMA, the tongue, palate etc are part of the mouth which is itself a subdivision of the face. ZFA includes a separate class 'oral region' which is part of the mouth, but excludes tongue and lips FMA + + + + FBbt:00003126 + + @@ -28715,14 +28638,14 @@ plexiform layer. BTO:0004698 FMA:49184 FMA:TA - + cavital oralis Wikipedia:Mouth - + @@ -28798,15 +28721,15 @@ plexiform layer. - + - - + + A fluid that is composed of blood plasma and erythrocytes. This class excludes blood analogues, such as the insect analog of blood. See UBERON:0000179 haemolymphatic fluid. @@ -28848,34 +28771,34 @@ plexiform layer. blood - + - + - + - + CL:tm - + https://github.com/obophenotype/uberon/issues/1330 - + Bgee:AN @@ -29179,7 +29102,7 @@ plexiform layer. - + @@ -29221,14 +29144,14 @@ plexiform layer. organism substance - + - + this relationship may be too strong and may be weakened in future @@ -29237,6 +29160,12 @@ plexiform layer. Material anatomical entity in a gaseous, liquid, semisolid or solid state; produced by anatomical structures or derived from inhaled and ingested substances that have been modified by anatomical structures as they pass through the body. http://orcid.org/0000-0001-9114-8737 + + + + FBbt:00007019 + + @@ -29315,6 +29244,12 @@ plexiform layer. Non-material anatomical entity of three dimensions, that is generated by morphogenetic or other physiologic processes; is surrounded by one or more anatomical structures; contains one or more organism substances or anatomical structures. http://orcid.org/0000-0001-9114-8737 + + + + FBbt:00007017 + + @@ -29364,6 +29299,12 @@ plexiform layer. Anatomical entity that has mass. http://orcid.org/0000-0001-9114-8737 + + + + FBbt:00007016 + + @@ -29400,6 +29341,12 @@ plexiform layer. Anatomical entity that has no mass. http://orcid.org/0000-0001-9114-8737 + + + + FBbt:00007015 + + @@ -29485,11 +29432,19 @@ plexiform layer. system GO:0048731 + + + + FBbt:00004856 + + IDOMAL:0002460 - https://orcid.org/0000-0003-4423-4370 + + + https://github.com/biopragmatics/biomappings @@ -29588,6 +29543,12 @@ plexiform layer. VHOG:0000671 WBbt:0007833 + + + + FBbt:00000001 + + @@ -29691,6 +29652,12 @@ plexiform layer. CARO:DOS http://orcid.org/0000-0001-9114-8737 + + + + FBbt:00007009 + + @@ -29758,6 +29725,12 @@ plexiform layer. Anatomical structure that consists of cell parts and cell substances and together does not constitute a cell or a tissue. http://orcid.org/0000-0001-9114-8737 + + + + FBbt:00007013 + + @@ -29777,7 +29750,6 @@ plexiform layer. FBbt:00007277 - IDOMAL:0002461 VHOG:0001737 uberon UBERON:0000477 @@ -29794,8 +29766,8 @@ plexiform layer. - IDOMAL:0002461 - https://orcid.org/0000-0003-4423-4370 + FBbt:00007277 + @@ -29866,6 +29838,12 @@ plexiform layer. Multicellular anatomical structure that consists of many cells of one or a few types, arranged in an extracellular matrix such that their long-range organisation is at least partly a repetition of their short-range organisation. CARO:0000043 + + + + FBbt:00007003 + + @@ -29933,6 +29911,12 @@ plexiform layer. CARO:0000055 http://orcid.org/0000-0001-9114-8737 + + + + FBbt:00007010 + + @@ -29971,7 +29955,7 @@ plexiform layer. - + @@ -30015,14 +29999,14 @@ plexiform layer. epithelium https://upload.wikimedia.org/wikipedia/commons/8/8f/Illu_epithelium.jpg - + - + http://palaeos.com/metazoa/porifera/homoscleromorpha.html @@ -30042,6 +30026,12 @@ plexiform layer. ISBN:978-0030259821 Ruppert EE, Fox RS, Barnes RD, Invertebrate zoology: a functional evolutionary approach (2003) p.59 http://bgee.unil.ch/ + + + + FBbt:00007005 + + @@ -30460,11 +30450,19 @@ plexiform layer. Obsoleted in ZFA. Note that embryo is not classified as an embryonic structure - an embryonic structure is only the parts of an embryo ZFA + + + + FBbt:00000052 + + IDOMAL:0000646 - https://orcid.org/0000-0003-4423-4370 + + + https://github.com/biopragmatics/biomappings @@ -30551,6 +30549,12 @@ plexiform layer. embryonic tissue FMA:69069 + + + + FBbt:00000110 + + @@ -30589,7 +30593,7 @@ plexiform layer. - + Primary germ layer that is the outer of the embryo's three germ layers and gives rise to epidermis and neural tissue. Primary germ layer that is the outer of the embryonic germ layers and gives rise to epidermis and neural tissue.[AAO] The Bilateria are triploblastic (with true endoderm, mesoderm, and ectoderm) (...).[well established][VHOG] @@ -30627,14 +30631,14 @@ plexiform layer. ectoderm http://upload.wikimedia.org/wikipedia/commons/1/19/Gray32.png - + - + Bgee:AN @@ -30662,6 +30666,12 @@ plexiform layer. ISBN:978-0878932504 Gilbert SF, Developmental Biology (2006) Limb development and evolution, p.722 http://bgee.unil.ch/ + + + + FBbt:00000111 + + @@ -30687,7 +30697,7 @@ plexiform layer. - + Primary germ layer that lies remote from the surface of the embryo and gives rise to internal tissues such as gut. The Bilateria are triploblastic (with true endoderm, mesoderm, and ectoderm) (...).[well established][VHOG] endodermal @@ -30724,14 +30734,14 @@ plexiform layer. http://upload.wikimedia.org/wikipedia/commons/c/c0/Endoderm2.png http://upload.wikimedia.org/wikipedia/commons/d/df/Gray10.png - + - + Bgee:AN @@ -30750,6 +30760,12 @@ plexiform layer. ISBN:978-0878932504 Gilbert SF, Developmental Biology (2006) Limb development and evolution, p.722 http://bgee.unil.ch/ + + + + FBbt:00000125 + + @@ -30776,7 +30792,7 @@ plexiform layer. - + The middle germ layer of the embryo, between the endoderm and ectoderm. Primary germ layer that is the middle of the embryonic germ layers.[AAO] @@ -30821,7 +30837,7 @@ plexiform layer. mesoderm http://upload.wikimedia.org/wikipedia/commons/e/e8/Mesoderm.png - + @@ -30834,7 +30850,7 @@ plexiform layer. - + Bgee:AN @@ -30868,6 +30884,12 @@ plexiform layer. sponges do not seem to have a mesoderm and accordingly Amphimedon lacks transcription factors involved in mesoderm development (Fkh, Gsc, Twist, Snail)[http://www.nature.com/nature/journal/v466/n7307/full/nature09201.html]. Mesoderm may not be homologous across verteberates https://github.com/obophenotype/uberon/wiki/The-neural-crest + + + + FBbt:00000126 + + @@ -30977,6 +30999,12 @@ plexiform layer. stomodeal-hypophyseal primordium XAO:0000269 + + + + FBbt:00000439 + + @@ -31056,7 +31084,7 @@ plexiform layer. - + @@ -31122,14 +31150,14 @@ plexiform layer. cranial nerve II - + - + EHDAA2 @@ -31212,7 +31240,7 @@ plexiform layer. nervus opticus - + @@ -31220,7 +31248,7 @@ plexiform layer. nervus opticus [II] FMA:50863 FMA:TA - + @@ -31273,7 +31301,7 @@ plexiform layer. - + @@ -31350,14 +31378,14 @@ plexiform layer. https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Heart.glb https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Heart.glb - + - + MA @@ -31435,7 +31463,7 @@ plexiform layer. - + @@ -31460,7 +31488,7 @@ plexiform layer. - + The brain is the center of the nervous system in all vertebrate, and most invertebrate, animals. Some primitive animals such as jellyfish and starfish have a decentralized nervous system without a brain, while sponges lack any nervous system at all. In vertebrates, the brain is located in the head, protected by the skull and close to the primary sensory apparatus of vision, hearing, balance, taste, and smell[WP]. requires review for applicability to invertebrate structures, e.g. synganglion @@ -31523,11 +31551,11 @@ plexiform layer. https://ccf-ontology.hubmapconsortium.org/objects/v1.2/Allen_F_Brain.glb https://ccf-ontology.hubmapconsortium.org/objects/v1.2/Allen_M_Brain.glb - + - + @@ -31540,13 +31568,13 @@ plexiform layer. - + FMA - + Bgee:AN @@ -31590,6 +31618,12 @@ plexiform layer. ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.28, ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.165 http://bgee.unil.ch/ + + + + FBbt:00005095 + + @@ -31804,7 +31838,7 @@ plexiform layer. chiasma opticum Wikipedia:Optic_chiasm - + @@ -31823,14 +31857,14 @@ plexiform layer. chiasma NeuroNames:459 - + chiasma nervorum opticorum NeuroNames:459 - + @@ -31847,9 +31881,9 @@ plexiform layer. - - - + + + @@ -31874,7 +31908,7 @@ plexiform layer. - + @@ -31930,44 +31964,44 @@ plexiform layer. cornea http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg - + - + - + - + - + MA - + MA - + FMA-isa - + definitional @@ -32156,10 +32190,10 @@ plexiform layer. - - - - + + + + The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates. @@ -32210,44 +32244,44 @@ plexiform layer. retina http://upload.wikimedia.org/wikipedia/commons/e/ed/Human_eye_cross-sectional_view_grayscale.png - + - + - + - + - + FMA - + FMA - + FMA - + EHDAA2 @@ -32321,8 +32355,8 @@ plexiform layer. - - + + @@ -32358,24 +32392,24 @@ plexiform layer. eye - + - + - + PMID:21062451 - + PMID:21062451 @@ -32384,6 +32418,12 @@ plexiform layer. An organ that detects light. https://orcid.org/0000-0002-6601-2165 + + + + FBbt:00005162 + + @@ -32605,6 +32645,12 @@ plexiform layer. many anatomy ontologies consider gastrointestinal system synonymous with digestive system. here we follow MA in dividing digestive system into gastrointestinal and hepatobiliary. hepatobiliary includes the liver and biliary tract. species-specific AO classes are categorized according to whether liver is included. For example, XAO includes liver as part of XAO:0000125 alimentary system, so we assume this class is the more generic class MA + + + + FBbt:00005055 + + @@ -32646,6 +32692,7 @@ plexiform layer. We should divest ourselves of the view that earlier vertebrate groups were 'on their way' to becoming mammals, as clearly they were not such visionaries. Neither were their systems 'imperfect' as earlier anatomists thought. Instead, their circulatory systems served them well to address the ecological demands arising from their lifestyles.[well established][VHOG] AAO:0000959 CALOHA:TS-2103 + MESH:D002319 VHOG:0001248 Wikipedia:Circulatory_system uberon @@ -32693,12 +32740,19 @@ plexiform layer. ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.493 http://bgee.unil.ch/ + + + + MESH:D002319 + + https://github.com/biopragmatics/biomappings + systema cardiovasculare Wikipedia:Circulatory_system - + @@ -32779,7 +32833,7 @@ plexiform layer. musculi FMA:32558 FMA:TA - + @@ -32830,13 +32884,14 @@ plexiform layer. - + The nervous system is an organ system containing predominantly neuron and glial cells. In bilaterally symmetrical organism, it is arranged in a network of tree-like structures connected to a central body. The main functions of the nervous system are to regulate and control body functions, and to receive sensory input, process this information, and generate behavior [CUMBO]. + A regulatory system of the body that consists of neurons and neuroglial cells. The nervous system is divided into two parts, the central nervous system (CNS) and the peripheral nervous system (PNS). (Source: BioGlossary, www.Biology-Text.com)[TAO] Anatomical system consisting of nerve bodies and nerve fibers which regulate the response of the body to external and internal stimuli.[AAO] Nervous systems evolved in the ancestor of Eumetazoa.[well established][VHOG] @@ -32876,6 +32931,7 @@ plexiform layer. UBERON:0001016 + @@ -32883,14 +32939,14 @@ plexiform layer. http://upload.wikimedia.org/wikipedia/commons/b/b2/TE-Nervous_system_diagram.svg http://upload.wikimedia.org/wikipedia/commons/b/ba/Nervous_system_diagram.png - + - + Bgee:AN @@ -32933,6 +32989,12 @@ plexiform layer. ISBN:978-0198566694 Schmidt-Rhaesa A, The evolution of organ systems (2007) p.117 http://bgee.unil.ch/ + + + + FBbt:00005093 + + @@ -32956,7 +33018,7 @@ plexiform layer. systema nervosum Wikipedia:Nervous_system - + @@ -32978,9 +33040,10 @@ plexiform layer. - + The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the neural tube derivatives: the brain and spinal cord. In invertebrates it includes central ganglia plus nerve cord. + Part of the nervous system which includes the brain and spinal cord.[AAO] The brain and spinal cord. Kimmel et al, 1995.[TAO] The central nervous system (CNS) is the part of the nervous system which includes the brain, spinal cord, and nerve cell layer of the retina (CUMBO). @@ -33020,12 +33083,13 @@ plexiform layer. UBERON:0001017 + central nervous system - + @@ -33039,7 +33103,7 @@ plexiform layer. - + Bgee:AN @@ -33090,6 +33154,12 @@ plexiform layer. ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.28 (reference 1), ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.165 (reference 2), DOI:10.1016/j.cell.2007.02.040 Denes AS, Jekely G, Steinmetz PRH, Raible F, Snyman H, Prud'homme B, Ferrier DEK, Balavoine G and Arendt D, Molecular architecture of annelid nerve cord supports common origin of nervous system centralization in Bilateria. Cell (2007) (reference 3) http://bgee.unil.ch/ + + + + FBbt:00005094 + + @@ -33109,7 +33179,7 @@ plexiform layer. systema nervosum centrale FMA:55675 FMA:TA - + @@ -33164,6 +33234,12 @@ plexiform layer. White matter structure of CNS that contains axons that arise predominantly in one central nervous system part and terminate in another. Tracts are generally named by their region or origin followed by their region of primary termination, e.g., mammillothalamic tract contains axons that arise from neurons in the mammillary bodies and terminate in the thalamus. (CUMBO) http://neurolex.org/wiki/Cumbo_terms + + + + FBbt:00005100 + + @@ -33233,7 +33309,7 @@ plexiform layer. fasciculus - + @@ -33337,13 +33413,19 @@ plexiform layer. DOI:10.1073/pnas.97.9.4449 Shimeld SM and Holland PW. Vertebrate innovations. PNAS (2000) http://bgee.unil.ch/ + + + + FBbt:00007692 + + organa sensuum FMA:75259 FMA:TA - + @@ -33369,7 +33451,7 @@ plexiform layer. organa sensuum Wikipedia:Sensory_system - + @@ -33429,6 +33511,12 @@ plexiform layer. FB:FBrf0089570 http://flybase.org/reports/FBrf0178740.html + + + + FBbt:00005495 + + @@ -33549,6 +33637,14 @@ plexiform layer. The mature structure of the neural tube exists when the tube has been segmented into the forebrain, midbrain, hindbrain and spinal cord regions. In addition neural crest has budded away from the epithelium GO:0021915 + + + + MESH:D054259 + + + https://github.com/biopragmatics/biomappings + @@ -33560,7 +33656,7 @@ plexiform layer. tubus neuralis Wikipedia:Neural_tube - + @@ -33603,6 +33699,12 @@ plexiform layer. FMA:62955 http://orcid.org/0000-0001-9114-8737 + + + + FBbt:10000000 + + @@ -33737,7 +33839,7 @@ plexiform layer. textus muscularis nonstriatus FMA:14070 FMA:TA - + @@ -33756,7 +33858,7 @@ plexiform layer. textus muscularis levis; textus muscularis nonstriatus Wikipedia:Smooth_muscle_tissue - + @@ -33787,7 +33889,7 @@ plexiform layer. - + Simple squamous epithelium of mesodermal origin which lines serous membranes. Examples: mesothelium of pleura, mesothelium of peritoneum[FMA]. Wikipedia: The mesothelium is a membrane that forms the lining of several body cavities: the pleura (thoracal cavity), peritoneum (abdominal cavity including the mesentery) and pericardium (heart sac). Mesothelial tissue also surrounds the male internal reproductive organs (the tunica vaginalis testis) and covers the internal reproductive organs of women (the tunica serosa uteri). AEO:0000111 BTO:0002422 @@ -33812,14 +33914,14 @@ plexiform layer. mesothelium http://upload.wikimedia.org/wikipedia/commons/2/25/Mesothelium_peritoneal_wash_high_mag.jpg - + - + FMA @@ -34159,7 +34261,7 @@ plexiform layer. facia/facies Wikipedia:Face - + @@ -34192,7 +34294,7 @@ plexiform layer. - + A tube extending from the mouth to the anus. @@ -34213,6 +34315,7 @@ plexiform layer. FBbt:00003125 FMA:45615 MA:0000917 + MESH:D041981 NCIT:C34082 TAO:0000112 TGMA:0001819 @@ -34234,14 +34337,14 @@ plexiform layer. digestive tract - + - + NCBIBook:NBK10107 @@ -34294,6 +34397,19 @@ plexiform layer. we place the MA and EMAPA class here, although the intent is probably a smaller region. See https://github.com/obophenotype/uberon/issues/509 MA + + + + FBbt:00003125 + + + + + + MESH:D041981 + + https://github.com/biopragmatics/biomappings + @@ -34321,7 +34437,7 @@ plexiform layer. - + The ciliary muscle is a ring of smooth muscle in the middle layer of the eye that controls the eye's accommodation for viewing objects at varying distances and regulates the flow of aqueous humour through Schlemm's canal. [WP,unvetted]. BTO:0000654 @@ -34344,7 +34460,7 @@ plexiform layer. ciliary muscle http://upload.wikimedia.org/wikipedia/commons/2/28/Gray872.png - + @@ -34363,7 +34479,7 @@ plexiform layer. - + FMA @@ -34401,7 +34517,7 @@ plexiform layer. musculus ciliaris Wikipedia:Ciliary_muscle - + @@ -34504,7 +34620,7 @@ plexiform layer. - + @@ -34556,14 +34672,14 @@ plexiform layer. eyelid https://upload.wikimedia.org/wikipedia/commons/8/84/Eye_makeup.jpg - + - + multiple @@ -34703,7 +34819,7 @@ plexiform layer. camera anterior bulbi oculi Wikipedia:Anterior_chamber_of_eyeball - + @@ -34836,7 +34952,7 @@ plexiform layer. tunica vasculosa bulbi Wikipedia:Uvea - + @@ -34858,7 +34974,7 @@ plexiform layer. - + @@ -34901,14 +35017,14 @@ plexiform layer. iris - + - + XAO @@ -34980,7 +35096,7 @@ plexiform layer. - + @@ -35032,14 +35148,14 @@ plexiform layer. corneal epithelium http://upload.wikimedia.org/wikipedia/commons/6/66/Gray871.png - + - + ISBN:0781772214 @@ -35089,7 +35205,7 @@ plexiform layer. epithelium anterius corneae FMA:58263 FMA:TA - + @@ -35102,7 +35218,7 @@ plexiform layer. e. anterius corneae Wikipedia:Corneal_epithelium - + @@ -35135,16 +35251,16 @@ plexiform layer. - - + + - - + + @@ -35186,44 +35302,44 @@ plexiform layer. sclera http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg - + - + - + - + - + FMA - + ZFA - + ISBN:0781772214 - + cjm ISBN:0781772214 Wikipedia @@ -35283,7 +35399,7 @@ plexiform layer. - + @@ -35322,14 +35438,14 @@ plexiform layer. ciliary body http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg - + - + ISBN:0781772214 @@ -35368,7 +35484,7 @@ plexiform layer. corpus ciliare Wikipedia:Ciliary_body - + @@ -35377,14 +35493,14 @@ plexiform layer. - + - + @@ -35447,24 +35563,24 @@ plexiform layer. optic choroid http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg - + - + - + MA - + Wikipedia @@ -35532,7 +35648,7 @@ plexiform layer. choroidea Wikipedia:Choroid - + @@ -35564,7 +35680,7 @@ plexiform layer. - + @@ -35613,14 +35729,14 @@ plexiform layer. substantia propria of cornea http://upload.wikimedia.org/wikipedia/commons/6/66/Gray871.png - + - + cjm ISBN:0781772214 Wikipedia @@ -35676,7 +35792,7 @@ plexiform layer. substantia propria corneae FMA:58306 FMA:TA - + @@ -35697,9 +35813,9 @@ plexiform layer. - - - + + + A double layer covering the ciliary body that produces aqueous humor. BTO:0001770 @@ -35719,15 +35835,15 @@ plexiform layer. ciliary epithelium - + - + - + @@ -35740,19 +35856,19 @@ plexiform layer. - + MA - + MP - + Wikipedia @@ -35875,7 +35991,7 @@ plexiform layer. - + @@ -35936,14 +36052,14 @@ plexiform layer. pigmented layer of retina http://upload.wikimedia.org/wikipedia/commons/5/55/Gray881.png - + - + Wikipedia @@ -36006,7 +36122,7 @@ plexiform layer. stratum pigmentosum retinae FMA:58627 FMA:TA - + @@ -36019,7 +36135,7 @@ plexiform layer. p. pigmentosa retinae Wikipedia:Retinal_pigment_epithelium - + @@ -36032,7 +36148,7 @@ plexiform layer. stratum pigmentosa retinae Wikipedia:Retinal_pigment_epithelium - + @@ -36047,7 +36163,7 @@ plexiform layer. - + @@ -36081,14 +36197,14 @@ plexiform layer. photoreceptor layer of retina http://upload.wikimedia.org/wikipedia/commons/5/55/Gray881.png - + - + ZFA @@ -36132,7 +36248,7 @@ plexiform layer. stratum segmentorum externorum et internorum retinae FMA:58680 FMA:TA - + @@ -36226,7 +36342,7 @@ plexiform layer. stratum limitans externum retinae FMA:58683 FMA:TA - + @@ -36261,7 +36377,7 @@ plexiform layer. - + @@ -36308,14 +36424,14 @@ plexiform layer. outer nuclear layer of retina - + - + soma ZFA @@ -36353,7 +36469,7 @@ plexiform layer. stratum nucleare externum retinae FMA:58684 FMA:TA - + @@ -36485,7 +36601,7 @@ plexiform layer. stratum plexiforme externum retinae FMA:58685 FMA:TA - + @@ -36632,7 +36748,7 @@ plexiform layer. stratum nucleare internum retinae FMA:58686 FMA:TA - + @@ -36653,7 +36769,7 @@ plexiform layer. - + @@ -36712,7 +36828,7 @@ plexiform layer. ganglionic layer of retina http://upload.wikimedia.org/wikipedia/commons/5/55/Gray881.png - + @@ -36725,7 +36841,7 @@ plexiform layer. - + FMA @@ -36792,7 +36908,7 @@ plexiform layer. stratum ganglionicum retinae Wikipedia:Ganglion_cell_layer - + @@ -36801,7 +36917,7 @@ plexiform layer. - + @@ -36857,14 +36973,14 @@ plexiform layer. nerve fiber layer of retina - + - + FMA @@ -36902,7 +37018,7 @@ plexiform layer. stratum neurofibrarum retinae FMA:58688 FMA:TA - + @@ -36928,7 +37044,7 @@ plexiform layer. stratum neurofibrum retinae Wikipedia:Nerve_fiber_layer - + @@ -37038,7 +37154,7 @@ plexiform layer. stratum limitans internum retinae FMA:58689 FMA:TA - + @@ -37232,7 +37348,7 @@ plexiform layer. stratum plexiforme internum retinae Wikipedia:Inner_plexiform_layer - + @@ -37242,7 +37358,7 @@ plexiform layer. - + @@ -37278,14 +37394,14 @@ plexiform layer. aqueous humor of eyeball http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg - + - + FMA def states A and P located_in in EHDAA2 VHOG @@ -37340,7 +37456,7 @@ plexiform layer. humor aquosus FMA:58819 FMA:TA - + @@ -37376,6 +37492,7 @@ plexiform layer. EV:0100344 FMA:58822 MA:0001286 + MESH:D014822 NCIT:C13323 UMLS:C0229096 VHOG:0000795 @@ -37409,6 +37526,13 @@ plexiform layer. portion of vitreous humor FMA:67388 + + + + MESH:D014822 + + https://github.com/biopragmatics/biomappings + @@ -37421,7 +37545,7 @@ plexiform layer. humor vitreus FMA:58822 FMA:TA - + @@ -37467,7 +37591,7 @@ plexiform layer. - + @@ -37491,7 +37615,7 @@ plexiform layer. vitreous body http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg - + @@ -37504,7 +37628,7 @@ plexiform layer. - + neural ectoderm of optic cup ISBN:0781772214 @@ -37600,7 +37724,7 @@ plexiform layer. camera postrema bulbi oculi FMA:58848 FMA:TA - + @@ -37639,8 +37763,8 @@ plexiform layer. - - + + @@ -37673,24 +37797,24 @@ plexiform layer. anterior segment of eyeball http://upload.wikimedia.org/wikipedia/commons/b/ba/Cataract_in_human_eye.png - + - + - + FMA - + cjm @@ -37732,7 +37856,7 @@ plexiform layer. segmentum anterius bulbi oculi Wikipedia:Anterior_segment_of_eyeball - + @@ -37741,8 +37865,8 @@ plexiform layer. - - + + @@ -37772,24 +37896,24 @@ plexiform layer. posterior segment of eyeball http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg - + - + - + FMA - + cjm @@ -37816,7 +37940,7 @@ plexiform layer. segmentum posterius bulbi oculi Wikipedia:Posterior_segment_of_eyeball - + @@ -37825,9 +37949,9 @@ plexiform layer. - - - + + + @@ -37877,15 +38001,15 @@ plexiform layer. conjunctiva http://upload.wikimedia.org/wikipedia/commons/5/55/Gray883.png - + - + - + @@ -37898,19 +38022,19 @@ plexiform layer. - + cjm - + MA - + ISBN:0781772214 @@ -37946,7 +38070,7 @@ plexiform layer. tunica conjunctiva FMA:TA - + @@ -37974,7 +38098,7 @@ plexiform layer. - + The most anterior region of the brain including both the telencephalon and diencephalon. @@ -38021,14 +38145,14 @@ plexiform layer. forebrain http://upload.wikimedia.org/wikipedia/commons/5/54/EmbryonicBrain.svg - + - + definitional @@ -38104,14 +38228,14 @@ plexiform layer. - + - + The midbrain is the middle division of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes a ventral part containing the cerebral peduncles and a dorsal tectum containing the corpora quadrigemina and that surrounds the aqueduct of Sylvius connecting the third and fourth ventricles)[GO]. developmental relationships need revised @@ -38164,24 +38288,24 @@ plexiform layer. midbrain http://upload.wikimedia.org/wikipedia/commons/f/f9/Human_brain_inferior_view_description.JPG - + - + - + definitional - + Bgee:AN @@ -38267,7 +38391,7 @@ plexiform layer. mesencephalon Wikipedia:Midbrain - + @@ -38284,14 +38408,14 @@ plexiform layer. - + - + The division of the forebrain that develops from the foremost primary cerebral vesicle. @@ -38354,24 +38478,24 @@ plexiform layer. diencephalon http://upload.wikimedia.org/wikipedia/commons/5/54/EmbryonicBrain.svg - + - + - + definitional - + definitional @@ -38486,7 +38610,7 @@ plexiform layer. diencephalon Wikipedia:Diencephalon - + @@ -38643,14 +38767,14 @@ plexiform layer. bulbus FMA:62004 FMA:TA - + medulla oblonzata Wikipedia:Medulla_oblongata - + @@ -38775,14 +38899,14 @@ plexiform layer. tractus optici NeuroNames:460 - + tractus opticus Wikipedia:Optic_tract - + @@ -38809,7 +38933,7 @@ plexiform layer. - + Ventral part of the midbrain, separated from the hindbrain by the isthmus[ISBN:0471888893]. Subdivision of the midbrain lying anterior to the tectum and posterior to the substantia nigra and cerebral peduncle[FMA] The part of the midbrain extending from the substantia nigra to the cerebral aqueduct in a horizontal section of the midbrain. It forms the floor of the midbrain that surrounds the cerebral aqueduct[WP]. Together, our results reveal a shared basic organization in the tegmental domains of the diencephalon and midbrain of developing lamprey, indicating early appearance of the domain in vertebrate phylogeny.[well established][VHOG] @@ -38826,6 +38950,7 @@ plexiform layer. HBA:9002 MA:0000212 MAT:0000452 + MESH:D013681 SCTID:362392007 TAO:0000160 UMLS:C0039441 @@ -38849,14 +38974,14 @@ plexiform layer. midbrain tegmentum http://upload.wikimedia.org/wikipedia/commons/b/b6/Gray712.png - + - + ZFA @@ -38891,6 +39016,13 @@ plexiform layer. tegmentum ISBN:0471888893 + + + + MESH:D013681 + + https://github.com/biopragmatics/biomappings + @@ -38908,7 +39040,7 @@ plexiform layer. tegmentum mesencephali Wikipedia:Midbrain_tegmentum - + @@ -38921,7 +39053,7 @@ plexiform layer. tegmentum mesencephalicum NeuroNames:491 - + @@ -39035,8 +39167,8 @@ plexiform layer. - - + + @@ -39049,7 +39181,7 @@ plexiform layer. - + @@ -39108,34 +39240,34 @@ plexiform layer. blood vessel http://upload.wikimedia.org/wikipedia/commons/2/29/Circulatory_System_en.svg - + - + - + - + AEO - + EHDAA2 - + GO:0072360 @@ -39208,7 +39340,7 @@ plexiform layer. vas sanguineum Wikipedia:Blood_vessel - + @@ -39304,7 +39436,7 @@ plexiform layer. epithelium posterius corneae Wikipedia:Corneal_endothelium - + @@ -39448,6 +39580,14 @@ plexiform layer. EMAPA:37596 MA:th + + + + MESH:D066128 + + + https://github.com/biopragmatics/biomappings + @@ -39472,7 +39612,7 @@ plexiform layer. substantia grisea FMA:67242 FMA:TA - + @@ -39484,7 +39624,7 @@ plexiform layer. grisea - + @@ -39494,7 +39634,7 @@ plexiform layer. - + @@ -39507,7 +39647,7 @@ plexiform layer. - + The most posterior of the three principal regions of the brain. In mammals and birds the hindbrain is divided into a rostral metencephalon and a caudal myelencephalon. In zebrafish, with the exception of the cerebellum, the ventral remainder of the metencephalon can be separated only arbitrarily from the more caudal myelencephalic portion of the medulla oblongata (From: Neuroanatomy of the Zebrafish Brain)[ZFA]. Organ component of neuraxis that has as its parts the pons, cerebellum and medulla oblongata[FMA]. @@ -39558,25 +39698,25 @@ plexiform layer. hindbrain http://upload.wikimedia.org/wikipedia/commons/5/54/EmbryonicBrain.svg - + - + - + modified-source-relation ABA - + Bgee:AN @@ -39828,6 +39968,12 @@ plexiform layer. in FMA embryo is_a embryonic structure FMA + + + + FBbt:00004208 + + @@ -40005,6 +40151,7 @@ plexiform layer. FMA:71221 MA:0002986 MAT:0000148 + MESH:D013131 MIAA:0000148 TAO:0000317 VHOG:0000317 @@ -40080,6 +40227,13 @@ plexiform layer. EMAPA:37721 MA:th + + + + MESH:D013131 + + https://github.com/biopragmatics/biomappings + @@ -40395,7 +40549,7 @@ plexiform layer. - + Vasculature that is part of the eye region. not part of the eye in ZFA. Note this changed to a blood vessel in ZFA @@ -40418,14 +40572,14 @@ plexiform layer. https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb - + - + ISBN:0781772214 @@ -40484,7 +40638,7 @@ plexiform layer. - + @@ -40518,14 +40672,14 @@ plexiform layer. musculoskeletal system - + - + check ctenophore @@ -40639,7 +40793,7 @@ plexiform layer. cavitas thoracis Wikipedia:Thoracic_cavity - + @@ -40663,15 +40817,15 @@ plexiform layer. - + - - + + Part of the central nervous system located in the vertebral canal continuous with and caudal to the brain; demarcated from brain by plane of foramen magnum. It is composed of an inner core of gray matter in which nerve cells predominate, and an outer layer of white matter in which myelinated nerve fibers predominate, and surrounds the central canal. (CUMBO). TODO - add superclass to unify with VNC? @@ -40730,34 +40884,34 @@ plexiform layer. https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Spinal_Cord.glb https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Spinal_Cord.glb - + - + - + - + ZFA - + definitional - + definitional @@ -40829,14 +40983,14 @@ plexiform layer. fissura cerebro-cerebellaris NeuroNames:22 - + fissura cerebrocerebellaris NeuroNames:22 - + @@ -40844,7 +40998,7 @@ plexiform layer. medulla spinalis BTO:0001279 Wikipedia:Spinal_cord - + @@ -41008,7 +41162,7 @@ plexiform layer. truncus encephali Wikipedia:Brainstem - + @@ -41021,35 +41175,35 @@ plexiform layer. lamella pallidi incompleta NeuroNames:236 - + lamina medullaris accessoria NeuroNames:236 - + lamina medullaris incompleta pallidi NeuroNames:236 - + lamina pallidi incompleta NeuroNames:236 - + truncus encephalicus BTO:0000146 - + @@ -41143,6 +41297,14 @@ plexiform layer. NIF https://github.com/SciCrunch/NIF-Ontology/issues/83 + + + + MESH:D066127 + + + https://github.com/biopragmatics/biomappings + @@ -41184,7 +41346,7 @@ plexiform layer. substantia alba Wikipedia:White_matter - + @@ -41199,7 +41361,7 @@ plexiform layer. - + @@ -41240,14 +41402,14 @@ plexiform layer. EDITOR_NOTE check the FMA placement here; ncit placement of body cavity here probably not correct coelemic cavity lumen - + - + definitional @@ -41280,6 +41442,12 @@ plexiform layer. body cavity BTO:0001707 + + + + FBbt:00005060 + + @@ -41355,9 +41523,9 @@ plexiform layer. - - - + + + @@ -41412,15 +41580,15 @@ plexiform layer. notochord http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + - + - + @@ -41439,19 +41607,19 @@ plexiform layer. - + http://tolweb.org/Chordata/2499 - + ZFA - + EHDAA2 @@ -41526,7 +41694,7 @@ plexiform layer. notochorda Wikipedia:Notochord - + @@ -41536,8 +41704,8 @@ plexiform layer. - - + + Somites are spheres of epithelial cells that form sequentially along the anterior-posterior axis of the embryo through mesenchymal to epithelial transition of the presomitic mesoderm. EDITOR_NOTE currently classified as an epithelial vesicle, consistent with EHDAA2 and https://github.com/obophenotype/uberon/wiki/The-neural-crest. Consider making 'somitic mesoderm' a separate term and correlate with regionalization processes. Consider moving ZFA term to 'trunk somite' as it is part of the trunk @@ -41583,11 +41751,11 @@ plexiform layer. somite http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + - + @@ -41600,13 +41768,13 @@ plexiform layer. - + GOTAX:0000352 - + ZFA @@ -41709,7 +41877,7 @@ plexiform layer. somitus Wikipedia:Somite - + @@ -41719,12 +41887,12 @@ plexiform layer. - - - - - - + + + + + + A specialized region of ectoderm found between the neural ectoderm (neural plate) and non-neural ectoderm and composed of highly migratory pluripotent cells that delaminate in early embryonic development from the dorsal neural tube and give rise to an astounding variety of differentiated cell types[MP]. EDITOR_NOTE consider including subclasses for pre- and post- migratory (e.g. sheets/paths/streams). @@ -41764,66 +41932,66 @@ plexiform layer. http://upload.wikimedia.org/wikipedia/commons/5/5f/Gray644.png https://upload.wikimedia.org/wikipedia/commons/8/8f/Neural_Crest.png - + - + - + - + - + - + - + XAO https://github.com/obophenotype/uberon/wiki/The-neural-crest - + Hall and others restrict NC to vertebrates but we opt for a less restrictive constraint to avoid inconsistencies when areas such as P1 area of pallium in hagfishes inherit cell lineage from telecephalon-contributing NC cells ISBN:0073040584 - + BTO - + PMID:11523831 - + pre migratory https://github.com/obophenotype/uberon/wiki/The-neural-crest - + PMID:11523831 @@ -41891,7 +42059,7 @@ plexiform layer. crista neuralis Wikipedia:Neural_crest - + @@ -41964,6 +42132,12 @@ plexiform layer. DOI:10.1046/j.1469-7580.2001.19910133.x Graham A. The development and evolution of the pharyngeal arches. J Anat (2001) http://bgee.unil.ch/ + + + + FBbt:00001057 + + @@ -41975,7 +42149,7 @@ plexiform layer. epithelium tubi neuralis; neuroectoderma Wikipedia:Neuroectoderm - + @@ -42206,14 +42380,14 @@ plexiform layer. - + - + Anatomical system that is involved in the production of hematopoietic cells. @@ -42258,24 +42432,24 @@ plexiform layer. hematopoietic system - + - + - + FMA - + definitional @@ -42340,8 +42514,8 @@ plexiform layer. - - + + @@ -42367,11 +42541,11 @@ plexiform layer. iris epithelium - + - + @@ -42384,13 +42558,13 @@ plexiform layer. - + MA - + MP @@ -42423,7 +42597,7 @@ plexiform layer. epithelium pigmentosum iridis FMA:58517 FMA:TA - + @@ -42519,7 +42693,7 @@ plexiform layer. epiblastus Wikipedia:Epiblast - + @@ -42540,7 +42714,7 @@ plexiform layer. - + Ectodermal placode that develops in the head into a part of the sensory nervous system. With a few exceptions (lens, adenohypophyseal), cranial placodes are neurogenic. Do not merge with neurogenic placode Comparisons of developmental gene expression suggest that the anterior ectoderm in amphioxus may be homologous to the vertebrate olfactory placode, the only vertebrate placode with primary, not secondary, neurons @@ -42560,7 +42734,7 @@ plexiform layer. cranial placode - + @@ -42573,7 +42747,7 @@ plexiform layer. - + PMID:11523831 PMID:22512454 @@ -42778,7 +42952,7 @@ plexiform layer. - + @@ -42791,7 +42965,7 @@ plexiform layer. - + The part of the brain that is the morphological boundary between the midbrain and hindbrain and that is the location of an organizing center which patterns the midbrain and hindbrain primordia of the neural plate. consider adding class for organizer. Consider adding separate class for isthmus as a structure Lampreys also have an MHB [midbrain hindbrain boundary], expressing a similar repertoire of regulatory gene cognates as in gnathostomes.[well established][VHOG] @@ -42821,11 +42995,11 @@ plexiform layer. midbrain-hindbrain boundary - + - + @@ -42839,13 +43013,13 @@ plexiform layer. - + ZFA - + ZFA @@ -43010,7 +43184,7 @@ plexiform layer. - + Unsegmented field of paraxial mesoderm present posterior to the most recently formed somite pair, from which somites will form. Unsegmented field of paraxial mesoderm present posterior to the most recently formed somite pair, from which somites will form. Kimmel et al, 1995.[TAO] It is reasonable to assume that the proximate invertebrate ancestor of the vertebrates had an amphioxus-like tail bud in its larval stage. This archetypal tail bud would have (...) (3) lacked any component of mesenchyme cells, (4) budded off new mesodermal segments directly, without any intervening zone of presomitic mesoderm (...). Then, early in vertebrate evolution, epithelium-to-mesenchyme interconversions (and the gene networks for effecting them) became prominent features of development. (...) In any case, conspicuous mesenchymal components tended to be added to the vertebrate tail bud itself. In addition, a mesenchymatous presomitic mesoderm (not a part of the tail bud proper) came to intervene between the tail bud and the forming somites.[well established][VHOG] @@ -43035,14 +43209,14 @@ plexiform layer. presomitic mesoderm - + - + Bgee:AN @@ -43284,7 +43458,7 @@ plexiform layer. - + @@ -43322,7 +43496,7 @@ plexiform layer. eye primordium - + @@ -43335,7 +43509,7 @@ plexiform layer. - + PMID:16496288 XAO @@ -43391,8 +43565,8 @@ plexiform layer. - - + + @@ -43421,24 +43595,24 @@ plexiform layer. optic cup - + - + - + ZFA - + ZFA @@ -43503,7 +43677,7 @@ plexiform layer. - + @@ -43544,7 +43718,7 @@ plexiform layer. lens placode http://upload.wikimedia.org/wikipedia/commons/2/2f/Gray864.png - + @@ -43557,7 +43731,7 @@ plexiform layer. - + ZFA @@ -43610,7 +43784,7 @@ plexiform layer. placoda lentis Wikipedia:Lens_placode - + @@ -43621,9 +43795,9 @@ plexiform layer. - - - + + + A region of embryonic ectodermal cells that lie directly above the notochord. During neurulation, they change shape and produce an infolding of the neural plate (the neural fold) that then seals to form the neural tube[XAO]. The earliest recognizable dorsal ectodermal primordium of the central nervous system present near the end of gastrulation before infolding to form the neural keel; consists of a thickened pseudostratified epithelium[ZFA]. The earliest recognizable dorsal ectodermal primordium of the central nervous system present near the end of gastrulation before infolding to form the neural keel; consists of a thickened pseudostratified epithelium. Kimmel et al, 1995.[TAO] (...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord that is located dorsal to the notochord (...).[well established][VHOG] @@ -43655,34 +43829,34 @@ plexiform layer. neural plate https://upload.wikimedia.org/wikipedia/commons/8/8f/Neural_Crest.png - + - + - + - + GOTAX:0000352 - + Wikipedia - + Bgee:AN @@ -43713,6 +43887,14 @@ plexiform layer. ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.28 http://bgee.unil.ch/ + + + + MESH:D054258 + + + https://github.com/biopragmatics/biomappings + @@ -43724,7 +43906,7 @@ plexiform layer. lamina neuralis Wikipedia:Neural_plate - + @@ -43793,7 +43975,7 @@ plexiform layer. - + The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube[GO]. Mesoderm lateral to the neural tube and notochord that is divided into cranial and post-cranial portions. The trunk portions further segment into somites.[AAO] Presently, Cephalochordata, Urochordata, and Vertebrata are placed as subphyla of the phylum Chordata, in which the overall organization of embryonic tissues (dorsal hollow nerve cord, ventral digestive tract, axial notochord, and bilateral paraxial mesoderm) is largely conserved. In contrast, the echinoderms and hemichordates are sister groups of the chordates and they lack the notochord and paraxial mesoderm. Thus, the basic mesodermal organization of vertebrates must have appeared first in the common ancestor of the chordates.[well established][VHOG] @@ -43822,7 +44004,7 @@ plexiform layer. paraxial mesoderm http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + @@ -43835,7 +44017,7 @@ plexiform layer. - + Bgee:AN @@ -43895,7 +44077,7 @@ plexiform layer. mesoderma paraxiale Wikipedia:Paraxial_mesoderm - + @@ -43947,7 +44129,7 @@ plexiform layer. - + @@ -43991,7 +44173,7 @@ plexiform layer. lateral plate mesoderm http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + @@ -44004,7 +44186,7 @@ plexiform layer. - + EHDAA2 VHOG @@ -44079,7 +44261,7 @@ plexiform layer. mesoderma laminae lateralis Wikipedia:Lateral_plate_mesoderm - + @@ -44088,15 +44270,15 @@ plexiform layer. - - + + - + Bilateral groups of cells consisting of three rows: one row of endocardial precursors medially and two rows of myocardical precursors laterally. The two populations fuse at the midline to form the heart rudiment or cone. should probably be merged with heart rudiment. Bilateral groups of cells consisting of three rows: one row of endocardial precursors medially and two rows of myocardical precursors laterally. The two populations fuse at the midline between 21 and 26 somites to form the heart rudiment or cone. Stainier 2001.[TAO] @@ -44116,15 +44298,15 @@ plexiform layer. heart primordium - + - + - + @@ -44137,19 +44319,19 @@ plexiform layer. - + ZFA - + ZFA - + XAO @@ -44204,8 +44386,8 @@ plexiform layer. - - + + Ventral somitic compartment that is a precursor of the axial skeleton[XAO]. Sclerotomes eventually differentiate into the vertebrae and most of the skull. The caudal (posterior) half of one sclerotome fuses with the rostral (anterior) half of the adjacent one to form each vertebra. From their initial location within the somite, the sclerotome cells migrate medially towards the notochord. These cells meet the sclerotome cells from the other side to form the vertebral body. From this vertebral body, sclerotome cells move dorsally and surround the developing spinal cord, forming the vertebral arch[WP]. Skeletogenic portion of somites.[AAO] The vertebrate sclerotome has no equivalent in amphioxus and is a novelty linked with the evolution of the axial skeleton.[well established][VHOG] @@ -44233,11 +44415,11 @@ plexiform layer. sclerotome http://upload.wikimedia.org/wikipedia/commons/9/96/Gray65.png - + - + @@ -44256,13 +44438,13 @@ plexiform layer. - + VHOG:0000680 - + ZFA @@ -44302,7 +44484,9 @@ plexiform layer. BTO:0006255 - https://orcid.org/0000-0003-4423-4370 + + + https://github.com/biopragmatics/biomappings @@ -44322,7 +44506,7 @@ plexiform layer. sclerotomus Wikipedia:Sclerotome - + @@ -44420,7 +44604,7 @@ plexiform layer. pedunculus opticus Wikipedia:Optic_stalk - + @@ -44520,7 +44704,7 @@ plexiform layer. crista neuralis cranialis Wikipedia:Cranial_neural_crest - + @@ -44660,7 +44844,7 @@ plexiform layer. mesenchyma Wikipedia:Mesenchyme - + @@ -44686,7 +44870,7 @@ plexiform layer. - + Mesenchyme that is part of a developing camera-type eye. TODO - change mesenchyme relationships to precursor_of EHDAA2:0000485 @@ -44698,14 +44882,14 @@ plexiform layer. UBERON:0003314 eye mesenchyme - + - + EHDAA2 @@ -45563,7 +45747,7 @@ plexiform layer. - + The part of the coelom in the embryo between the somatopleuric and splanchnopleuric mesoderm; the principal body cavities of the trunk (thoracic, abdominal, and pelvic) arise from this embryonic part of the coelom. consider merging with coelom. TODO - add spatial relationships to halves of LPM. Note the OG places XAO and ZFA coelem terms here. editor note: TODO check ZFA, which appears to be a structure present in adults (...) I regard it unlikely that coeloms of all bilaterian animals are comparable and evolved very early. Considering all these questions, few convincing characters concerning the evolution of body cavities remain to be named. (...) A segmental coelom appears to have evolved at least two times, in Annelida and in Myomerata (Acrania and Craniota).[well established][VHOG] @@ -45579,14 +45763,14 @@ plexiform layer. intraembryonic coelom - + - + Wikipedia @@ -45691,7 +45875,7 @@ plexiform layer. - + The part of the retina that contains neurons and photoreceptor cells[GO]. (...) an essentially similar sequence of events occurs during the embryonic development of the vertebrate eye. The eye initially develops as a single median evagination of the diencephalon that soon bifurcates to form the paired optic vesicles. As each optic vesicle grows towards the body surface, its proximal part narrows as the optic stalk, and its distal part invaginates to form a two-layered optic cup. (...) The outer layer of the optic cup becomes the pigment layer of the retina, whereas the inner layer differentiates into the photoreceptive cells and neuronal layers of the retina.[well established][VHOG] @@ -45723,14 +45907,14 @@ plexiform layer. retinal neural layer - + - + Bgee:AN @@ -45786,7 +45970,7 @@ plexiform layer. stratum nervosum retinae FMA:58628 FMA:TA - + @@ -45830,6 +46014,12 @@ plexiform layer. GO:0060562 PMID:12526790 + + + + FBbt:00007474 + + @@ -45988,7 +46178,7 @@ plexiform layer. - + The layer of undifferentiated, proliferating cells that line the neural tube lumen that is the immediate transformation of the germinal neuroepithelium. consider merging with 'ventricular zone'; note that the MA class probably does not belong here, as this is an embryonic structure The layer of undifferentiated, proliferating cells that line the neural tube lumen @@ -46006,7 +46196,7 @@ plexiform layer. neural tube ventricular layer - + @@ -46019,7 +46209,7 @@ plexiform layer. - + NCBIBook:NBK10047 @@ -46079,7 +46269,7 @@ plexiform layer. - + @@ -46103,7 +46293,7 @@ plexiform layer. neural tube mantle layer - + @@ -46116,7 +46306,7 @@ plexiform layer. - + by division NCBIBook:NBK10047 @@ -46153,7 +46343,7 @@ plexiform layer. - + @@ -46170,14 +46360,14 @@ plexiform layer. neural tube marginal layer - + - + forms from axons @@ -46452,9 +46642,9 @@ plexiform layer. - - - + + + @@ -46487,34 +46677,34 @@ plexiform layer. optic vesicle http://upload.wikimedia.org/wikipedia/commons/e/e0/Gray863.png - + - + - + - + ZFA - + GO-def - + ZFA @@ -46630,8 +46820,8 @@ plexiform layer. - - + + A specific region of the lateral mesoderm that will form the primary beating heart tube. In mammals the primary heart field gives rise to the left ventricle. this term denotes the primary heart field; GO:0003128 denotes the superclass of primary and secondary: specific region of the lateral mesoderm into the area which will form the primary beating heart tube[GO:0003138] XAO:0004185 @@ -46644,24 +46834,24 @@ plexiform layer. UBERON:0004140 primary heart field - + - + - + GO:0003128 - + https://orcid.org/0000-0003-3308-6245 @@ -46720,7 +46910,7 @@ plexiform layer. - + An epithelial tube that will give rise to the mature heart. the paired, longitudinal, endothelial-lined channels formed from the cardiogenic mesoderm in embryonic development; angiogenic cell clusters (aka angioblastic cords) located in a horse-shoe shape configuration in the cardiogenic plate coalesce to form the right and left endocardial heart tubes which then fuse in cephalo-caudal direction to form a single primitive heart tube. AAO:0010411 @@ -46740,14 +46930,14 @@ plexiform layer. heart tube - + - + ZFA-modified @@ -46828,7 +47018,7 @@ plexiform layer. - + @@ -46844,14 +47034,14 @@ plexiform layer. eye muscle - + - + MA @@ -47055,7 +47245,7 @@ plexiform layer. - + A transparent homogeneous acellular layer found between the substantia propria and the endothelial layer of the cornea[MP]. Acellular anatomical structure composed of collagen, Descemet's membrane is secreted as a basement membrane of the corneal endothelium. Located between the stroma and the corneal endothelium, it is approximately 0.15 micrometer thick at 6 months post-fertilization.[ZFIN] @@ -47085,14 +47275,14 @@ plexiform layer. Descemet's membrane https://github.com/obophenotype/uberon/issues/15 - + - + Cline et al @@ -47142,7 +47332,7 @@ plexiform layer. lamina limitans posterior corneae FMA:58309 FMA:TA - + @@ -47292,14 +47482,14 @@ plexiform layer. lamina limitans anterior corneae FMA:58273 FMA:TA - + Reichert's membrane http://sourceforge.net/tracker/?func=detail&aid=2956371&group_id=76834&atid=974957 - + @@ -47544,6 +47734,7 @@ plexiform layer. An endothelium that lines the blood vasculature. Other endothelia may line lymph vessels, the heart. + BTO:0000766 CALOHA:TS-2155 EMAPA:35176 @@ -47554,6 +47745,7 @@ plexiform layer. ZFA:0005257 uberon UBERON:0004638 + blood vessel endothelium @@ -47804,6 +47996,12 @@ plexiform layer. We explicitly merge the NCITA terms here NCIT + + + + FBbt:00005317 + + @@ -47877,7 +48075,7 @@ plexiform layer. - + Organ consisting of skeletal tissue. Encompasses whole bones, fused bones, cartilaginious elements, teeth, dermal denticles. Organ entity that is typically involved in mechanical support and may have different skeletal tissue compositions at different stages.[VSAO] Organ entity that may have different tissue compositions at different stages and is typically involved in mechanical support.[TAO] @@ -47893,14 +48091,14 @@ plexiform layer. skeletal element - + - + VSAO @@ -47945,7 +48143,7 @@ plexiform layer. - + @@ -47984,14 +48182,14 @@ plexiform layer. UBERON:0004770 articular system - + - + FMA @@ -48246,6 +48444,12 @@ plexiform layer. Anatomical structure that connects two or more adjacent skeletal elements or hardened body parts. http://orcid.org/0000-0002-6601-2165 + + + + FBbt:00005811 + + @@ -48298,6 +48502,12 @@ plexiform layer. A proximal-distal subdivision of the digestive tract. http://orcid.org/0000-0002-6601-2165 + + + + FBbt:00100315 + + @@ -48649,6 +48859,12 @@ plexiform layer. CARO FMA + + + + FBbt:00007060 + + @@ -48900,7 +49116,7 @@ plexiform layer. - + Portion of primordial embryonic connective tissue of the developing head, consisting of mesenchymal cells supported in interlaminar jelly, that derive mostly from the mesoderm and contribute to head connective tissue, bone and musculature in conjunction with cranial neural crest cells. Mesoderm that will give rise, along with cranial neural crest cells, to connective tissue, bone and musculature in the head. (Source: BioGlossary, www.Biology-Text.com)[TAO] EFO:0003492 @@ -48922,14 +49138,14 @@ plexiform layer. head mesenchyme - + - + EHDAA2 @@ -48996,7 +49212,7 @@ plexiform layer. - + Mesenchyme that is part of a developing trunk. EFO:0003485 EHDAA2:0002092 @@ -49012,14 +49228,14 @@ plexiform layer. trunk mesenchyme - + - + EHDAA2 @@ -49042,7 +49258,7 @@ plexiform layer. - + The posterior part of the developing vertebrate hindbrain or the corresponding part of the adult brain composed of the medulla oblongata and a portion of the fourth ventricle; as well as the glossopharyngeal nerve (CN IX), vagus nerve (CN X), accessory nerve (CN XI), hypoglossal nerve (CN XII), and a portion of the vestibulocochlear nerve (CN VIII).[BTO,WP]. The posterior of the two brain vesicles formed by specialization of the rhombencephalon in the developing embryo, it comprises the medulla oblongata. [TFD][VHOG] @@ -49067,14 +49283,14 @@ plexiform layer. myelencephalon http://upload.wikimedia.org/wikipedia/commons/5/54/EmbryonicBrain.svg - + - + definitional @@ -49104,6 +49320,14 @@ plexiform layer. ISBN:978-0878932504 Gilbert SF, Developmental Biology (2006) p.381-382, ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.500 http://bgee.unil.ch/ + + + + MESH:D054024 + + + https://github.com/biopragmatics/biomappings + @@ -49209,6 +49433,12 @@ plexiform layer. An array of photoreceptors and any supporting cells found in an eye. https://orcid.org/0000-0002-6601-2165 + + + + FBbt:00004200 + + @@ -49272,6 +49502,12 @@ plexiform layer. developing anatomical structure + + + + FBbt:00007006 + + @@ -49601,7 +49837,7 @@ plexiform layer. - + Portion of tissue that is part of the eye and gives rise to the mature, fully layered cornea. TAO:0002188 ZFA:0001688 @@ -49609,7 +49845,7 @@ plexiform layer. UBERON:0005427 corneal primordium - + @@ -49628,7 +49864,7 @@ plexiform layer. - + ZFA @@ -49651,7 +49887,7 @@ plexiform layer. - + Multi-tissue structure that arises from the heart rudiment and will become the heart tube. BTO:0006179 EHDAA2:0001512 @@ -49670,14 +49906,14 @@ plexiform layer. primitive heart tube - + - + ZFA @@ -49690,7 +49926,9 @@ plexiform layer. BTO:0006179 - https://orcid.org/0000-0003-4423-4370 + + + https://github.com/biopragmatics/biomappings @@ -49870,7 +50108,7 @@ plexiform layer. membrana basalis Wikipedia:Basement_membrane - + @@ -49886,7 +50124,7 @@ plexiform layer. - + A delimited region of dense mesenchyme within looser mesenchyme. AEO:0000148 EHDAA2_RETIRED:0003148 @@ -49896,7 +50134,7 @@ plexiform layer. UBERON:0005856 developing mesenchymal condensation - + @@ -49915,7 +50153,7 @@ plexiform layer. - + AEO-modified-relation @@ -49972,9 +50210,9 @@ plexiform layer. - - - + + + A serous sac which is the aggregate of the conjunctiva plus the conjunctival space. EMAPA:18233 FMA:20291 @@ -49985,15 +50223,15 @@ plexiform layer. UBERON:0005908 conjunctival sac - + - + - + @@ -50006,19 +50244,19 @@ plexiform layer. - + FMA - + HPO:pr - + MA @@ -50111,7 +50349,7 @@ plexiform layer. skeleton axiale Wikipedia:Axial_skeleton - + @@ -50174,7 +50412,7 @@ plexiform layer. neurofibra FMA:5914 FMA:TA - + @@ -50194,7 +50432,7 @@ plexiform layer. neurofibra Wikipedia:Nerve_fiber - + @@ -50273,7 +50511,7 @@ plexiform layer. - + @@ -50296,14 +50534,14 @@ plexiform layer. future diencephalon - + - + EHDAA2 @@ -50486,7 +50724,7 @@ plexiform layer. - + @@ -50510,14 +50748,14 @@ plexiform layer. future spinal cord - + - + EHDAA2 @@ -50554,7 +50792,7 @@ plexiform layer. - + The notochordal plate is the dorsal part of the notochordal process when the ventral portion breaks down. It is continuous laterally with the endoderm that composes the roof of the primitive foregut and is in contact dorsally with the neural tube. The folding off of the notochordal plate gives rise to the notochord. TODO - check ordering; awaiting confirmation from JB The notochordal plate is the dorsal part of the notochordal process when the ventral portion breaks down. It is continuous laterally with the endoderm that composes the roof of the primitive foregut and is in contact dorsally with the neural tube. The folding off of the notochordal plate gives rise to the notochord. [Carson_JL, Dehart_DB, Developmental_Dynamics_(1994)_201:_260-278, Gesteland_K_and_Schoenwolf_GC, Inagaki_T, Morphogenesis_of_the_murine_node_and_notochordal_plate, The_prechordal_plate, Vrablic_T, see_Mueller_F_and_O'Rahilly_R, the_rostral_end_of_the_notochord_and_nearby_median_features_in_staged_human_embryos._Cells_Tissues_Organs_(2003)_173:_1-20_and_Sulik_K][VHOG] @@ -50569,7 +50807,7 @@ plexiform layer. notochordal plate - + @@ -50582,7 +50820,7 @@ plexiform layer. - + EHDAA2 @@ -50619,7 +50857,7 @@ plexiform layer. - + A midline cellular cord formed from the migration of mesenchymal cells from the primitive knot. EHDAA2:0001279 EHDAA:224 @@ -50636,14 +50874,14 @@ plexiform layer. The notochordal process grows cranially until it reaches the prechordal plate, the future site of the mouth. In this area the ectoderm is attached directly to the endoderm without intervening mesoderm. This area is known as the oropharyngeal membrane, and it will break down to become the mouth. At the other end of the primitive streak the ectoderm is also fused directly to the endoderm; this is known as the cloacal membrane (proctodeum), or primordial anus. notochordal process - + - + EHDAA2 @@ -51547,7 +51785,7 @@ plexiform layer. - + A hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood or analogs[GO,modified]. note we reserve the subclass 'heart' from the vertebrate multi-chambered heart. 'The first heart-like organ is believed to have appeared 500my ago in an ancestral bilaterian'. Amniotes: four-chambered heart. Amphibians: two atria, one ventricle, pulmonary; fish: single atrium and ventricle; amphioxus: tubular, non-striated, closed, unidirectional; ascidians: tubular, striated, open, bidirectional; arthropods: tubular, open; C elegans: contractile pharynx; Cnideria: striated muscle cells associated with gastrodermis SPD:0000130 @@ -51562,14 +51800,14 @@ plexiform layer. Gene notes: Bmp, Nkx, Gata primary circulatory organ - + - + GO uses blood circulation generically to include the haemolymphatic fluid of arthropods @@ -51724,8 +51962,8 @@ plexiform layer. - - + + @@ -51752,24 +51990,24 @@ plexiform layer. presumptive hindbrain - + - + - + XAO-abduced - + cjm @@ -51826,7 +52064,7 @@ plexiform layer. - + @@ -51845,14 +52083,14 @@ plexiform layer. presumptive midbrain hindbrain boundary - + - + ZFA @@ -51891,7 +52129,7 @@ plexiform layer. - + @@ -51908,14 +52146,14 @@ plexiform layer. presumptive segmental plate - + - + https://github.com/obophenotype/uberon/wiki/The-neural-crest EDHAA2 @@ -52014,7 +52252,7 @@ plexiform layer. - + @@ -52040,7 +52278,7 @@ plexiform layer. presumptive paraxial mesoderm - + @@ -52056,7 +52294,7 @@ plexiform layer. - + https://github.com/obophenotype/uberon/issues/1277 @@ -52138,7 +52376,7 @@ plexiform layer. - + A neural decussation that is part of a diencephalon. FMA:62446 diencephalon decussation @@ -52146,7 +52384,7 @@ plexiform layer. UBERON:0007425 decussation of diencephalon - + @@ -52159,7 +52397,7 @@ plexiform layer. - + Obol @@ -52234,7 +52472,7 @@ plexiform layer. - + Mesenchyme with little extracellular matrix. AEO:0000146 EHDAA2:0003146 @@ -52242,7 +52480,7 @@ plexiform layer. UBERON:0007524 dense mesenchyme tissue - + @@ -52255,7 +52493,7 @@ plexiform layer. - + AEO @@ -52471,6 +52709,12 @@ plexiform layer. FBbt:00005426 http://flybase.org/reports/FBrf0178740.html + + + + FBbt:00005426 + + @@ -52495,7 +52739,7 @@ plexiform layer. - + An axon tract that is part of a brain. the NIFSTD class 'nerve tract' is classified under 'regional part of brain', so it may seem like it belongs here, but actually includes spinal cord tracts FMA:83848 @@ -52505,14 +52749,14 @@ plexiform layer. UBERON:0007702 tract of brain - + - + cjm @@ -52540,7 +52784,7 @@ plexiform layer. - + Anatomical system that consists of all blood and lymph vessels. consider merging with vasculature @@ -52559,14 +52803,14 @@ plexiform layer. vascular system - + - + MA @@ -52699,7 +52943,7 @@ plexiform layer. - + @@ -52716,14 +52960,14 @@ plexiform layer. UBERON:0009142 entire embryonic mesenchyme - + - + EHDAA2 @@ -52819,8 +53063,8 @@ plexiform layer. - - + + TODO - developmental relationships for lines TAO:0007044 ZFA:0007044 @@ -52830,24 +53074,24 @@ plexiform layer. UBERON:0009615 midbrain hindbrain boundary neural plate - + - + - + ZFA - + https://github.com/obophenotype/uberon/issues/438 Bgee:AN @@ -52881,14 +53125,14 @@ plexiform layer. - + - + @@ -52913,24 +53157,24 @@ plexiform layer. presumptive midbrain - + - + - + ZFA - + ZFA @@ -52976,7 +53220,7 @@ plexiform layer. - + EHDAA2:0002094 trunk and cervical paraxial mesenchyme uberon @@ -52984,14 +53228,14 @@ plexiform layer. UBERON:0009618 trunk paraxial mesoderm - + - + EHDAA2 @@ -53013,7 +53257,7 @@ plexiform layer. - + EFO:0003704 TAO:0005041 ZFA:0005041 @@ -53023,14 +53267,14 @@ plexiform layer. anterior lateral plate mesoderm - + - + ZFA @@ -53086,14 +53330,14 @@ plexiform layer. - + EHDAA2:0001315 EHDAA:1122 uberon UBERON:0009920 optic neural crest - + @@ -53106,7 +53350,7 @@ plexiform layer. - + EHDAA2 @@ -53158,6 +53402,12 @@ plexiform layer. An anatomical structure that has more than one cell as a part. CARO:0010000 + + + + FBbt:00100313 + + @@ -53240,7 +53490,7 @@ plexiform layer. - + @@ -53265,14 +53515,14 @@ plexiform layer. eyeball of camera-type eye - + - + FMA @@ -53313,8 +53563,8 @@ plexiform layer. - - + + Portion of tissue that is dorsolateral to the floor plate and part of the midbrain. DHBA:12322 EFO:0003567 @@ -53328,11 +53578,11 @@ plexiform layer. midbrain basal plate - + - + @@ -53345,13 +53595,13 @@ plexiform layer. - + EHDAA2 - + ZFA @@ -53379,7 +53629,7 @@ plexiform layer. - + Portion of neural tube that gives rise to the midbrain. we follow ZFA in temporally dividing midbrain NT from presumptive midbrain, but in future this may be collapsed TAO:0007039 @@ -53388,14 +53638,14 @@ plexiform layer. UBERON:0010286 midbrain neural tube - + - + ZFA @@ -53422,7 +53672,7 @@ plexiform layer. - + @@ -53438,14 +53688,14 @@ plexiform layer. UBERON:0010312 immature eye - + - + definitional @@ -53691,7 +53941,7 @@ plexiform layer. processus ciliares FMA:TA - + @@ -53710,7 +53960,7 @@ plexiform layer. processus ciliares Wikipedia:Ciliary_processes - + @@ -53719,8 +53969,8 @@ plexiform layer. - - + + Anatomical cluster consisting of the skeletal elements (i.e. bone elements, cartilage elements, cartilage condensations) that are part of an individual subdivision of the organism. Excludes joints. Anatomical cluster consisting of the skeletal elements that are part of the skeleton.[VSAO] FMA:23879 @@ -53733,11 +53983,11 @@ plexiform layer. subdivision of skeleton - + - + @@ -53750,13 +54000,13 @@ plexiform layer. - + UBERONREF:0000003 - + VSAO @@ -53827,7 +54077,7 @@ plexiform layer. - + Subdivision of the skeletal system which consists of the postcranial axial skeleton plus associated joints. axial skeletal system FMA:302077 @@ -53837,7 +54087,7 @@ plexiform layer. postcranial axial skeletal system http://purl.obolibrary.org/obo/uberon/docs/The-axial-skeleton - + @@ -53850,7 +54100,7 @@ plexiform layer. - + cjm @@ -53934,12 +54184,14 @@ plexiform layer. + FBbt:00007330 FMA:67509 SCTID:91690000 uberon UBERON:0011216 + organ system subdivision @@ -53955,6 +54207,12 @@ plexiform layer. A subdivision of an anatomical system. http://orcid.org/0000-0002-6601-2165 + + + + FBbt:00007330 + + @@ -53962,7 +54220,7 @@ plexiform layer. - + Muscles within the eye (bulbus oculi).[AAO] AAO:0010038 EMAPA:18808 @@ -53973,14 +54231,14 @@ plexiform layer. UBERON:0011222 intra-ocular muscle - + - + EMAPA @@ -54233,7 +54491,7 @@ plexiform layer. textus connectivus collagenosus laxus FMA:19783 FMA:TA - + @@ -54241,7 +54499,7 @@ plexiform layer. textus connectivus laxus FMA:19783 FMA:TA - + @@ -54250,7 +54508,7 @@ plexiform layer. - + @@ -54292,7 +54550,7 @@ plexiform layer. anterior uvea - + @@ -54305,7 +54563,7 @@ plexiform layer. - + MP @@ -54662,7 +54920,6 @@ plexiform layer. The region of the organism associated with the visceral organs. - Cardinal body part, which consists of a maximal set of diverse subclasses of organ and organ part spatially associated with the vertebral column and ribcage. Examples: There is only one body proper[FMA:231424]. AEO:0000103 BTO:0001489 @@ -54672,7 +54929,6 @@ plexiform layer. body whole body UBERON:0013702 - body proper @@ -54820,6 +55076,12 @@ plexiform layer. FBC:DOS FBbt:00007278 + + + + FBbt:00007278 + + @@ -55085,7 +55347,7 @@ plexiform layer. - + @@ -55108,7 +55370,7 @@ plexiform layer. UBERON:0016887 entire extraembryonic component - + @@ -55121,7 +55383,7 @@ plexiform layer. - + AEO @@ -55612,6 +55874,12 @@ plexiform layer. Material anatomical entity consisting of multiple anatomical structures that are not connected to each other. CARO:0020000 + + + + FBbt:00007276 + + @@ -55688,7 +55956,7 @@ plexiform layer. adnexa oculi http://medical-dictionary.thefreedictionary.com/ocular+adnexa - + @@ -55727,7 +55995,7 @@ plexiform layer. structurae oculi accessoriae Wikipedia:Accessory_visual_structures - + @@ -56083,6 +56351,42 @@ plexiform layer. /////////////////////////////////////////////////////////////////////////////////////// --> + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + @@ -56113,6 +56417,26 @@ plexiform layer. + + + + + + + + + + + + + + + + + + + + diff --git a/src/ontology/subsets/eye_upper_slim.tsv b/src/ontology/subsets/eye_upper_slim.tsv index 01bb2f0dd..4b5094794 100644 --- a/src/ontology/subsets/eye_upper_slim.tsv +++ b/src/ontology/subsets/eye_upper_slim.tsv @@ -1,322 +1,320 @@ ?x ?label -_:B11339660X2D3dc4X2D4a16X2D8efaX2D5e02455511e4genid1018 -_:B11339660X2D3dc4X2D4a16X2D8efaX2D5e02455511e4genid1026 -_:B11339660X2D3dc4X2D4a16X2D8efaX2D5e02455511e4genid1033 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+_:B0eeff062X2D4c9fX2D4f5fX2D85faX2D91dcf1dacab2genid605 +_:B0eeff062X2D4c9fX2D4f5fX2D85faX2D91dcf1dacab2genid611 +_:B0eeff062X2D4c9fX2D4f5fX2D85faX2D91dcf1dacab2genid623 +_:B0eeff062X2D4c9fX2D4f5fX2D85faX2D91dcf1dacab2genid676 +_:B0eeff062X2D4c9fX2D4f5fX2D85faX2D91dcf1dacab2genid693 +_:B0eeff062X2D4c9fX2D4f5fX2D85faX2D91dcf1dacab2genid713 +_:B0eeff062X2D4c9fX2D4f5fX2D85faX2D91dcf1dacab2genid728 +_:B0eeff062X2D4c9fX2D4f5fX2D85faX2D91dcf1dacab2genid783 +_:B0eeff062X2D4c9fX2D4f5fX2D85faX2D91dcf1dacab2genid833 +_:B0eeff062X2D4c9fX2D4f5fX2D85faX2D91dcf1dacab2genid850 +_:B0eeff062X2D4c9fX2D4f5fX2D85faX2D91dcf1dacab2genid863 +_:B0eeff062X2D4c9fX2D4f5fX2D85faX2D91dcf1dacab2genid868 +_:B0eeff062X2D4c9fX2D4f5fX2D85faX2D91dcf1dacab2genid877 +_:B0eeff062X2D4c9fX2D4f5fX2D85faX2D91dcf1dacab2genid883 +_:B0eeff062X2D4c9fX2D4f5fX2D85faX2D91dcf1dacab2genid897 +_:B0eeff062X2D4c9fX2D4f5fX2D85faX2D91dcf1dacab2genid903 +_:B0eeff062X2D4c9fX2D4f5fX2D85faX2D91dcf1dacab2genid911 +_:B0eeff062X2D4c9fX2D4f5fX2D85faX2D91dcf1dacab2genid919 +_:B0eeff062X2D4c9fX2D4f5fX2D85faX2D91dcf1dacab2genid966 "continuant" "occurrent" "independent continuant" @@ -464,7 +462,6 @@ _:B11339660X2D3dc4X2D4a16X2D8efaX2D5e02455511e4genid969 "acidophilic cytoplasm" "basophilic cytoplasm" "polychromatophilic cytoplasm" - "increased nucleus size" "conjunctival epithelial cell" "ciliary muscle cell" "central nervous system neuron" @@ -772,15 +769,10 @@ _:B11339660X2D3dc4X2D4a16X2D8efaX2D5e02455511e4genid969 "quality" "morphology" "shape" - "qualitative" - "deviation (from_normal)" - "size" "closure" "structure" "branched" "circular" - "normal" - "increased size" "closed" "elliptic" "opacity" @@ -819,8 +811,6 @@ _:B11339660X2D3dc4X2D4a16X2D8efaX2D5e02455511e4genid969 "subcylindrical" "3-D shape" "tubular" - "increased quality" - "increased object quality" "fiber shaped" "superelliptic" "acidophilic" @@ -828,6 +818,7 @@ _:B11339660X2D3dc4X2D4a16X2D8efaX2D5e02455511e4genid969 "disconnected" "cell morphology" "polymeric" + "high nuclear/cytoplasmic ratio" "cortical bipolar morphology" "bitufted dendrite cell morphology" "anatomical structure quality" diff --git a/src/ontology/subsets/general_cell_types_upper_slim.json b/src/ontology/subsets/general_cell_types_upper_slim.json index 98de6c0af..423bc976d 100644 --- a/src/ontology/subsets/general_cell_types_upper_slim.json +++ b/src/ontology/subsets/general_cell_types_upper_slim.json @@ -4,9 +4,9 @@ "meta" : { "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2002/07/owl#versionInfo", - "val" : "2024-01-04" + "val" : "2024-02-13" } ], - "version" : "http://purl.obolibrary.org/obo/cl/releases/2024-01-04/subsets/general_cell_types_upper_slim.owl" + "version" : "http://purl.obolibrary.org/obo/cl/releases/2024-02-13/subsets/general_cell_types_upper_slim.owl" }, "nodes" : [ { "id" : "http://purl.obolibrary.org/obo/BFO_0000002", @@ -731,7 +731,7 @@ "xrefs" : [ "CARO:mah" ] }, "comments" : [ "The definition of cell is intended to represent all cells, and thus a cell is defined as a material entity and not an anatomical structure, which implies that it is part of an organism (or the entirety of one)." ], - "subsets" : [ "http://purl.obolibrary.org/obo/ubprop#_upper_level" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/ubprop#_upper_level" ], "xrefs" : [ { "val" : "CALOHA:TS-2035" }, { @@ -757,6 +757,7 @@ "lbl" : "neuronal receptor cell", "type" : "CLASS", "meta" : { + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "neuronal receptor cell (sensu Animalia)" @@ -782,7 +783,7 @@ "xrefs" : [ "GOC:tfm", "MESH:D013234" ] }, "comments" : [ "This term applies to metazoan. For plant stem cells, consider using PO:0004011 ‘initial cell’ or its parent PO:0004010 ‘meristematic cell’." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "animal stem cell" @@ -807,7 +808,7 @@ "xrefs" : [ "GOC:add", "GOC:dsd", "GOC:tfm", "PMID:19022770", "http://en.wikipedia.org/wiki/Hematopoietic_stem_cell" ] }, "comments" : [ "Markers differ between species, and two sets of markers have been described for mice. HSCs are reportedly CD34-positive, CD45-positive, CD48-negative, CD150-positive, CD133-positive, and CD244-negative." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "blood forming stem cell" @@ -916,7 +917,7 @@ "xrefs" : [ "GOC:add", "ISBN:0878932437", "MESH:D023461" ] }, "comments" : [ "This cell type is intended to be compatible with any vertebrate common myeloid progenitor. For mammalian CMP known to be CD34-positive, please use the term 'common myeloid progenitor, CD34-positive' (CL_0001059)." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "common myeloid precursor" @@ -970,7 +971,7 @@ "xrefs" : [ "GOC:add", "GOC:dsd", "GOC:tfm", "PMID:10407577", "PMID:16551251" ] }, "comments" : [ "CLP are CD7-positive, CD10-positive, CD19-negative, CD34-positive, CD45RA-positive, CD79a-negative, CD127-positive, AA4.1-positive, RAG-negative, Sca-1-low, sIgM-negative, sIgD-negative, TdT-negative, Vpre-B-negative, and pre-BCR-negative. Expression of transcription factors include E2A-positive, EBF-positive, Ikaros-negative, PU.1-negative, and Pax5-negative." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "common lymphocyte precursor" @@ -1035,6 +1036,7 @@ "xrefs" : [ "SANBI:mhl" ] }, "comments" : [ "define using PATO mulit-potent or oligopotent?" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "blast cell" @@ -1076,7 +1078,7 @@ "xrefs" : [ "ISBN:0517223651", "MESH:D005347", "http://en.wikipedia.org/wiki/Fibroblast" ] }, "comments" : [ "These cells may be vimentin-positive, fibronectin-positive, fsp1-positive, MMP-1-positive, collagen I-positive, collagen III-positive, and alpha-SMA-negative." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { "val" : "BTO:0000452" }, { @@ -1102,7 +1104,7 @@ "val" : "A cell that is usually found in a two-dimensional sheet with a free surface. The cell has a cytoskeleton that allows for tight cell to cell contact and for cell polarity where apical part is directed towards the lumen and the basal part to the basal lamina.", "xrefs" : [ "FB:ma", "GOC:tfm", "MESH:D004847" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "epitheliocyte" @@ -1137,7 +1139,7 @@ "val" : "A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube.", "xrefs" : [ "GO:0002065", "https://orcid.org/0000-0001-5208-3432" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" @@ -1152,7 +1154,7 @@ "val" : "A cell found predominately in the blood.", "xrefs" : [ "GOC:add", "GOC:tfm" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim" ], "xrefs" : [ { "val" : "FMA:62844" }, { @@ -1168,7 +1170,7 @@ "val" : "A type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex.", "xrefs" : [ "GOC:add", "GOC:tfm", "ISBN:0781735149" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "T lymphocyte" @@ -1211,6 +1213,7 @@ "xrefs" : [ "GOC:add", "GOC:tfm", "GO_REF:0000031", "ISBN:0781735149", "PMID:10428500", "PMID:15055519", "PMID:17380158" ] }, "comments" : [ "Morphology: Highly vesicular; markers: Surface: RANK, cFMS (MCSF receptor); Secreted: cathepsin K and TRAP (tartate resistant acid phosphatase); transcription factors: PU.1, cFOS, MITF, NFkB (p52); role or process: tissue remodelling: bone resorption; lineage: hematopoietic, myeloid." ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "chondroclast" @@ -1234,7 +1237,7 @@ "val" : "A leukocyte with abundant granules in the cytoplasm.", "xrefs" : [ "GOC:amm", "GOC:tfm", "MESH:D006098", "http://en.wikipedia.org/wiki/Granulocyte" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "granular leucocyte" @@ -1262,7 +1265,10 @@ }, { "id" : "http://purl.obolibrary.org/obo/CL_0000095", "lbl" : "neuron associated cell", - "type" : "CLASS" + "type" : "CLASS", + "meta" : { + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] + } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000100", "lbl" : "motor neuron", @@ -1272,7 +1278,7 @@ "val" : "An efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes or inhibits movement.", "xrefs" : [ "MESH:D009046", "PMID:16875686" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "motoneuron" @@ -1321,7 +1327,7 @@ "val" : "A vertebrate phagocyte with a single nucleus.", "xrefs" : [ "GOC:add", "GOC:tfm", "ISBN:0781735149" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { "val" : "BTO:0001433" } ], @@ -1340,7 +1346,7 @@ "xrefs" : [ "MESH:D009457" ] }, "comments" : [ "Not all glial cells develop from glioblasts, with microglia developing from the mesoderm instead. See https://github.com/obophenotype/cell-ontology/issues/1571" ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "neuroglial cell" @@ -1382,6 +1388,7 @@ "xrefs" : [ "FB:ma", "GOC:dsd", "PMCID:PMC2613570", "PMID:10102814", "PMID:16923606", "PMID:17986482", "PMID:19960544", "http://en.wikipedia.org/wiki/Mesenchymal_stem_cell", "http://www.copewithcytokines.de/cope.cgi?key=mesenchymal%20stem%20cells" ] }, "comments" : [ "Many but not all mesenchymal cells derive from the mesoderm. MSCs are reportedly CD3-negative, CD4-negative, CD5-negative, CD8-negative, CD11a-negative, CD11b-negative, CD14-negative, CD19-negative, CD29-positive, CD31-negative, CD34-negative, CD38-negative, CD40-negative, CD44-positive, CD45-negative, CD49-positive, CD54-positive, CD66b-negative, CD79a-negative, CD80-negative, CD102-positive, CD106-positive, CD117-positive, CD121a-positive, CD121b-positive, CD123-positive, CD124-positive, CD133-negative, CD146-positive, CD166-positive, CD271-positive, B220-negative, Gr1-negative, MHCI-positive, MHCII-negative, SSEA4-negative, sca1-positive, Ter119-negative, and glycophorin A-negative. Cultured MSCs are capable of producing stem cell factor, IL7, IL8, IL11, TGF-beta, cofilin, galectin-1, laminin-receptor 1, cyclophilin A, and MMP-2." ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "bone marrow stromal cells" @@ -1450,7 +1457,7 @@ "val" : "A fat-storing cell found mostly in the abdominal cavity and subcutaneous tissue of mammals. Fat is usually stored in the form of triglycerides.", "xrefs" : [ "MESH:D017667" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "adipose cell" @@ -1480,7 +1487,7 @@ "xrefs" : [ "GOC:add", "ISBN:0781735149" ] }, "comments" : [ "Note change of name; nearly all somatic cells can present antigens to T cells via MHC Class I complexes leading to effector responses, but professional antigen presenting cells constitutively express MHC Class II as well as costimulatory molecules, and thus can initiate immune responses via T cells." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003000", "pred" : "hasRelatedSynonym", @@ -1516,7 +1523,7 @@ "val" : "A pigment cell derived from the neural crest. Contains melanin-filled pigment granules, which gives a brown to black appearance.", "xrefs" : [ "SANBI:mhl" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "melanophore" @@ -1556,6 +1563,7 @@ "val" : "A cell that specializes in controlled release of one or more substances.", "xrefs" : [ "GOC:tfm", "ISBN:0721662544" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "BTO:0003659" }, { @@ -1585,7 +1593,7 @@ "val" : "A cell of an endocrine gland, ductless glands that secrete substances which are released directly into the circulation and which influence metabolism and other body functions.", "xrefs" : [ "MESH:D055098" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "endocrinocyte" @@ -1606,7 +1614,8 @@ "definition" : { "val" : "A cell whose primary function is to shorten.", "xrefs" : [ "FB:ma" ] - } + }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000187", @@ -1617,6 +1626,7 @@ "val" : "A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns.", "xrefs" : [ "MESH:D032342" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "muscle fiber" @@ -1651,7 +1661,7 @@ "val" : "A somatic cell located in skeletal muscle.", "xrefs" : [ "GOC:tfm" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "skeletal muscle cell" @@ -1677,7 +1687,7 @@ "val" : "A non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels. They develop from specialized myoblasts (smooth muscle myoblast).", "xrefs" : [ "MESH:D032389", "PMID:9315361", "http://en.wikipedia.org/wiki/Smooth_muscle_cell" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "non-striated muscle cell" @@ -1730,6 +1740,7 @@ "val" : "A cell specialized to detect and transduce light.", "xrefs" : [ "MESH:D010786" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "BTO:0001060" }, { @@ -1788,6 +1799,7 @@ "val" : "A cell of the middle germ layer of the embryo.", "xrefs" : [ "MESH:D008648" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "mesoblast" @@ -1860,6 +1872,7 @@ "val" : "Any cell capable of ingesting particulate matter via phagocytosis.", "xrefs" : [ "GOC:add", "ISBN:0721601464" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "BTO:0001044" }, { @@ -1878,7 +1891,7 @@ "xrefs" : [ "GOC:add", "GOC:tfm", "GO_REF:0000031", "PMID:16213494", "PMID:1919437" ] }, "comments" : [ "Morphology: Diameter 30_M-80 _M, abundant cytoplasm, low N/C ratio, eccentric nucleus. Irregular shape with pseudopods, highly adhesive. Contain vacuoles and phagosomes, may contain azurophilic granules; markers: Mouse & Human: CD68, in most cases CD11b. Mouse: in most cases F4/80+; role or process: immune, antigen presentation, & tissue remodelling; lineage: hematopoietic, myeloid." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "histiocyte" @@ -1908,7 +1921,7 @@ "val" : "A lymphocyte of B lineage that is capable of B cell mediated immunity.", "xrefs" : [ "GOC:add", "GOC:tfm", "GO_REF:0000031", "ISBN:0781735149" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "B lymphocyte" @@ -1940,6 +1953,7 @@ "lbl" : "eukaryotic cell", "type" : "CLASS", "meta" : { + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "MESH:D005057" } ] @@ -2053,7 +2067,7 @@ "val" : "A cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation. These cells are lineage negative (CD3-negative, CD19-negative, CD34-negative, and CD56-negative).", "xrefs" : [ "GOC:add", "ISBN:0781735149" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "interdigitating cell" @@ -2094,7 +2108,7 @@ "val" : "A connective tissue cell of an organ found in the loose connective tissue. These are most often associated with the uterine mucosa and the ovary as well as the hematopoietic system and elsewhere.", "xrefs" : [ "GOC:tfm", "MESH:D017154" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { "val" : "BTO:0002064" }, { @@ -2114,6 +2128,7 @@ "val" : "A precursor cell destined to differentiate into cardiac muscle cell.", "xrefs" : [ "GOC:tfm", "MESH:D032386" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cardiac muscle progenitor cell" @@ -2134,6 +2149,7 @@ "val" : "A precursor cell destined to differentiate into smooth muscle myocytes.", "xrefs" : [ "GOC:tfm", "MESH:D032390" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "myoblast, smooth muscle", @@ -2219,7 +2235,7 @@ "xrefs" : [ "MESH:D009474", "http://en.wikipedia.org/wiki/Neuron" ] }, "comments" : [ "These cells are also reportedly CD4-negative and CD200-positive. They are also capable of producing CD40L and IFN-gamma." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "nerve cell" @@ -2271,7 +2287,7 @@ "xrefs" : [ "GOC:add", "ISBN:0683073696", "ISBN:0781735149" ] }, "comments" : [ "Editors note: consider adding taxon constraint to vertebrata (PMID:18025161)" ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { "val" : "BTO:0000775" }, { @@ -2298,7 +2314,7 @@ "xrefs" : [ "GOC:amm", "GOC:dsd", "GOC:tfm", "GO_REF:0000031", "ISBN:0721601464", "MESH:D055014", "PMCID:PMC2213186", "PMCID:PMC548021", "PMID:16551251", "PMID:16647566", "http://en.wikipedia.org/wiki/CFU-GM", "http://www.copewithcytokines.de" ] }, "comments" : [ "Originally described in the dendritic cell ontology (DC_CL:0000042)(PMID:19243617). GMPs are reportedly CD16-positive, CD32-positive, CD34-positive, CD38-positive, CD45RA-positive, CD110-negative, CD117-positive, CD123-positive, and SCA1-negative." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "CFU-C , Colony forming unit in culture", @@ -2343,7 +2359,7 @@ "xrefs" : [ "GOC:tfm", "ISBN:0721601464" ] }, "comments" : [ "Morphology: Mononuclear cell, diameter 14-18 _M, fine azurophilic granules; markers: CD11b (shared with many other myeloid cells); location: Adult: bone marrow; Fetal: Liver, Yolk Sac; role or process: hematopoiesis, monocyte development; lineage: hematopoietic, myeloid." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { "val" : "BTO:0004657" }, { @@ -2382,7 +2398,7 @@ "xrefs" : [ "GO_REF:0000031", "MESH:D009000" ] }, "comments" : [ "Morphology: Mononuclear cell, diameter, 14 to 20 _M, N/C ratio 2:1-1:1. Nucleus may appear in variety of shapes: round, kidney, lobulated, or convoluted. Fine azurophilic granules present; markers: CD11b (shared with other myeloid cells), human: CD14, mouse: F4/80-mid,GR1-low; location: Blood, but can be recruited into tissues; role or process: immune & tissue remodelling; lineage: hematopoietic, myeloid." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { "val" : "BTO:0000876" }, { @@ -2404,7 +2420,7 @@ "val" : "A lymphocyte that can spontaneously kill a variety of target cells without prior antigenic activation via germline encoded activation receptors and also regulate immune responses via cytokine release and direct contact with other cells.", "xrefs" : [ "GOC:add", "ISBN:0781735149", "PMID:15771571" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "large granular lymphocyte" @@ -2443,7 +2459,8 @@ "definition" : { "val" : "A non-terminally differentiated cell that is capable of developing into a muscle cell.", "xrefs" : [ "GOC:add" ] - } + }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000723", @@ -2486,7 +2503,7 @@ "val" : "An achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue.", "xrefs" : [ "GOC:add", "GOC:tfm", "ISBN:978-0-323-05290-0" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "leucocyte" @@ -2523,7 +2540,7 @@ "xrefs" : [ "GOC:mtg_cardiacconduct_nov11", "GOC:tfm", "ISBN:0323052908", "PMID:22426062", "PMID:4711263" ] }, "comments" : [ "This class encompasses the muscle cells responsible for heart* contraction in both vertebrates and arthropods. The ultrastucture of a wide range of arthropod heart cells has been examined including spiders, horseshoe crabs, crustaceans (see Sherman, 1973 and refs therein) and insects (see Lehmacher et al (2012) and refs therein). According to these refs, the cells participating in heart contraction in all cases are transversely striated. Insects hearts additionally contain ostial cells, also transversely striated muscle cells, but which do not participate in heart contraction." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "cardiocyte" @@ -2567,6 +2584,7 @@ "val" : "A cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage.", "xrefs" : [ "GOC:add" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "BTO:0001441" }, { @@ -2583,7 +2601,8 @@ "definition" : { "val" : "A cell of the monocyte, granulocyte, or mast cell lineage.", "xrefs" : [ "GOC:add" ] - } + }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000775", @@ -2594,7 +2613,7 @@ "val" : "Any of the immature or mature forms of a granular leukocyte that in its mature form has a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes.", "xrefs" : [ "GOC:add", "GOC:amm", "GOC:tfm", "ISBN:0721601464" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "PMN" @@ -2656,6 +2675,7 @@ "xrefs" : [ "GOC:add", "PMID:10449155", "PMID:17332250", "PMID:9521319" ] }, "comments" : [ "These cells are CD1a-negative, CD1b-positive, CD11a-positive, CD11c-positive, CD13-positive, CD14-negative, CD20-negative, CD21-negative, CD33-positive, CD40-negative, CD50-positive, CD54-positive, CD58-positive, CD68-negative, CD80-negative, CD83-negative, CD85j-positive, CD86-positive, CD89-negative, CD95-positive, CD120a-negative, CD120b-positive, CD123-negative, CD178-negative, CD206-negative, CD207-negative, CD209-negative, and TNF-alpha-negative. Upon TLR stimulation, they are capable of producing high levels of TNF-alpha, IL-6, CXCL8 (IL-8)." ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "interdigitating cell" @@ -2713,7 +2733,7 @@ "xrefs" : [ "GOC:add", "GOC:dsd", "ISBN:0781735149", "PMID:12633665", "PMID:16551251", "PMID:18432934" ] }, "comments" : [ "Human pro-B cells are reportedly CD10-positive, CD22-positive, CD34-positive, CD38-positive, CD45-low, CD48-positive, CD79a-positive, CD127-positive, CD184-positive, RAG-positive, TdT-positive, Vpre-B-positive, pre-BCR-negative, IgD-negative, and IgM-negative. Transcription factors expressed: Pax5-positive, EBF-positive, E2A-negative, Ikaros-negative, and PU.1-negative." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "pre-pro B cell", @@ -2761,6 +2781,7 @@ "val" : "A lymphoid progenitor cell of the T cell lineage, with some lineage specific marker expression, but not yet fully committed to the T cell lineage.", "xrefs" : [ "GOC:add", "ISBN:0781735149" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "pro-T lymphocyte" @@ -2788,7 +2809,7 @@ "xrefs" : [ "GOC:add", "GOC:tfm", "PMID:19022770" ] }, "comments" : [ "Markers differ between mouse and human." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "MPP" @@ -2816,6 +2837,7 @@ "xrefs" : [ "GOC:add", "GOC:tfm" ] }, "comments" : [ "Note that this is a class of cell types, not an identified single cell type." ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "lymphoid progenitor cell" @@ -2838,7 +2860,7 @@ "xrefs" : [ "GOC:add", "GOC:tfm", "PMID:19022770" ] }, "comments" : [ "Note that this is a class of cell types, not an identified single cell type." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "myeloid progenitor cell" @@ -2864,7 +2886,7 @@ "val" : "A leukocyte with a single non-segmented nucleus in the mature form.", "xrefs" : [ "GOC:add" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "mononuclear leukocyte" @@ -2905,6 +2927,7 @@ "val" : "A cell of a hematopoietic lineage.", "xrefs" : [ "GOC:add", "GO_REF:0000031" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "haematopoietic cell" @@ -2935,7 +2958,7 @@ "xrefs" : [ "GOC:amm", "GO_REF:0000031", "PMID:17850486" ] }, "comments" : [ "Originally described in the dendritic cell ontology (DC_CL:0000003)(PMID:19243617) These cells are also CD20-negative, MHCII-positive." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "interdigitating cell" @@ -3017,7 +3040,7 @@ "val" : "A lymphocyte that lacks characteristic T cell, B cell, myeloid cell, and dendritic cell markers, that functions as part of the innate immune response to produce cytokines and other effector responses.", "xrefs" : [ "GOC:add", "GOC:dsd", "PMID:23292121", "PMID:23348417" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" @@ -3059,6 +3082,7 @@ "val" : "A progenitor cell that can give rise to plasmacytoid and myeloid dendritic cells, and to monocytes and macrophages.", "xrefs" : [ "GOC:tfm", "PMID:19273628" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "MDP" @@ -3138,6 +3162,7 @@ "xrefs" : [ "GOC:tfm", "ISBN:0618947256" ] }, "comments" : [ "MH consider whether bone marrow cells are bone cells in the structural sense vs. being part of bone organ sense." ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "BTO:0004850" }, { @@ -3202,6 +3227,7 @@ "val" : "A cell that is part of the nervous system.", "xrefs" : [ "GOC:tfm", "ISBN:0618947256" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "CALOHA:TS-2040" }, { @@ -3224,6 +3250,7 @@ "val" : "A cell of the supporting or framework tissue of the body, arising chiefly from the embryonic mesoderm and including adipose tissue, cartilage, and bone.", "xrefs" : [ "GOC:tfm", "ISBN:0618947256" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "CALOHA:TS-2096" }, { @@ -3379,7 +3406,8 @@ "definition" : { "val" : "Any hematopoietic cell that is a precursor of some other hematopoietic cell type.", "xrefs" : [ "GOC:dos" ] - } + }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0008002", @@ -3390,6 +3418,7 @@ "val" : "A transversely striated, synctial cell of skeletal muscle. It is formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.", "xrefs" : [ "GOC:tfm", "ISBN:0323052908" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "MESH:D018485" } ] @@ -3415,7 +3444,7 @@ "definition" : { "val" : "A non-polarised cell precursor cell that is part of some mesenchyme, is associated with the cell matrix but is not connected to other cells and is capable of migration." }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "mesenchyme cell" @@ -3472,7 +3501,8 @@ "definition" : { "val" : "A cell of the neural crest. Neural crest cells are multipotent. Premigratory neural crest cells are found at the neural plate boarder, some of which will undergo ectomesynchymal transition and delamination to form migratory neural crest cells.", "xrefs" : [ "https://orcid.org/0000-0001-5208-3432", "https://orcid.org/0000-0002-9900-7880" ] - } + }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0011026", @@ -3483,6 +3513,7 @@ "val" : "A precursor cell that has a tendency to differentiate into a specific type of cell. They are descendants of stem cells, only they are more constrained in their differentiation potential or capacity for self-renewal, and are often more limited in both senses.", "xrefs" : [ "ISBN:978-1-62808-994-3", "https://doi.org/10.1016/B978-0-12-409503-8.00002-0" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0001-5208-3432" @@ -3497,7 +3528,8 @@ "val" : "A cell that, by division or terminal differentiation, can give rise to other cell types.", "xrefs" : [ "GOC:dos" ] }, - "comments" : [ "Work is needed on GO 'cell differentiation' before it is clear whether the equivalent class definition 'native cell' that capable_of some 'cell differentiation' works. Also, may want to consider merging this with non-terminally differentiated cell." ] + "comments" : [ "Work is needed on GO 'cell differentiation' before it is clear whether the equivalent class definition 'native cell' that capable_of some 'cell differentiation' works. Also, may want to consider merging this with non-terminally differentiated cell." ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0017500", @@ -3533,23 +3565,6 @@ "val" : "2009-12-22T04:24:54Z" } ] } - }, { - "id" : "http://purl.obolibrary.org/obo/CL_0017505", - "lbl" : "increased nucleus size", - "type" : "CLASS", - "meta" : { - "definition" : { - "val" : "A nucleus size quality which is relatively high compared to the amount of cytoplasm present in the same cell.", - "xrefs" : [ "GOC:tfm" ] - }, - "basicPropertyValues" : [ { - "pred" : "http://purl.org/dc/terms/contributor", - "val" : "https://orcid.org/0000-0003-1980-3228" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", - "val" : "2009-12-23T10:53:24Z" - } ] - } }, { "id" : "http://purl.obolibrary.org/obo/CL_1001610", "lbl" : "bone marrow hematopoietic cell", @@ -4551,7 +4566,7 @@ "type" : "CLASS", "meta" : { "definition" : { - "val" : "A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex).", + "val" : "A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex).", "xrefs" : [ "GOC:pdt" ] }, "comments" : [ "Note that, in addition to forming the root of the cellular component ontology, this term is recommended for the annotation of gene products whose cellular component is unknown. When this term is used for annotation, it indicates that no information was available about the cellular component of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this." ], @@ -4591,7 +4606,7 @@ "xrefs" : [ "GOC:go_curators" ] }, "comments" : [ "Note that this term is intended to annotate gene products that are not attached to the cell surface. For gene products from multicellular organisms which are secreted from a cell but retained within the organism (i.e. released into the interstitial fluid or blood), consider the cellular component term 'extracellular space ; GO:0005615'." ], - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_yeast", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "extracellular" @@ -4749,7 +4764,7 @@ "xrefs" : [ "ISBN:0198547684" ] }, "comments" : [ "Chromosomes include parts that are not part of the chromatin. Examples include the kinetochore." ], - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_yeast", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "interphase chromosome" @@ -4797,7 +4812,7 @@ "val" : "The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.", "xrefs" : [ "ISBN:0198547684" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_yeast", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "xrefs" : [ { "val" : "Wikipedia:Cytoplasm" } ], @@ -4880,7 +4895,7 @@ "val" : "The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.", "xrefs" : [ "ISBN:0716731363" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_yeast", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "juxtamembrane" @@ -4995,7 +5010,7 @@ "val" : "Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction.", "xrefs" : [ "ISBN:0198506732" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_pombe", "http://purl.obolibrary.org/obo/go#goslim_yeast", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_pombe", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" @@ -5011,7 +5026,7 @@ "xrefs" : [ "GOC:dos", "GOC:dph", "GOC:jl", "GOC:mah" ] }, "comments" : [ "Note that this term should not be used for direct annotation. It should be possible to make a more specific annotation to one of the children of this term, for e.g. to transmembrane transport, to microtubule-based transport or to vesicle-mediated transport." ], - "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "single-organism transport" @@ -6605,7 +6620,7 @@ "xrefs" : [ "GOC:mtg_signal", "GOC:mtg_signaling_feb11", "GOC:signaling" ] }, "comments" : [ "Note that a signal is any variable property or parameter that serves to convey information, and may be a physical entity such as a gene product or small molecule, a photon, or a change in state such as movement or voltage change." ], - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pombe", "http://purl.obolibrary.org/obo/go#goslim_yeast", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pombe", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "biological signaling" @@ -6705,7 +6720,7 @@ "val" : "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon.", "xrefs" : [ "GOC:jl", "GOC:mah", "http://www.cogsci.princeton.edu/~wn/" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cell projection organisation" @@ -7029,7 +7044,7 @@ "val" : "A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues.", "xrefs" : [ "GOC:BHF", "GOC:mah", "GOC:rph", "NIF_Subcellular:nlx_subcell_20090513", "PMID:21123617", "PMID:28089324" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "proteinaceous extracellular matrix" @@ -7759,7 +7774,7 @@ "val" : "A prolongation or process extending from a cell, e.g. a flagellum or axon.", "xrefs" : [ "GOC:jl", "http://www.cogsci.princeton.edu/~wn/" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "cell process" @@ -7815,7 +7830,7 @@ "val" : "The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.", "xrefs" : [ "GOC:mah" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_pir" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_pir" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "biopolymer metabolic process", @@ -7831,6 +7846,9 @@ "val" : "multicellular organismal macromolecule metabolic process" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/26424" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0034960" }, { @@ -7867,7 +7885,7 @@ "val" : "Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane.", "xrefs" : [ "GOC:go_curators" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "xrefs" : [ { "val" : "NIF_Subcellular:sao1539965131" }, { @@ -8553,12 +8571,15 @@ "val" : "The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.", "xrefs" : [ "GO_REF:0000021" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_plant" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_plant" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "development of an anatomical structure" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/26424" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] @@ -8586,7 +8607,7 @@ "val" : "Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another.", "xrefs" : [ "GOC:dgh", "GOC:dph", "GOC:isa_complete", "GOC:mlg" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cell locomotion" @@ -8767,7 +8788,7 @@ "xrefs" : [ "GOC:ai", "GOC:bf" ] }, "comments" : [ "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ], - "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_manually_annotate", "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_manually_annotate", "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "physiological response to stimulus" @@ -9156,7 +9177,7 @@ "val" : "A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.", "xrefs" : [ "GOC:dph", "GOC:tb" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_pombe", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_pombe", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cellular membrane organisation" @@ -9332,6 +9353,7 @@ "val" : "The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon.", "xrefs" : [ "GOC:mah" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "organic molecular entity metabolic process" @@ -9343,6 +9365,9 @@ "val" : "organic substance metabolism" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/26424" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "mah" }, { @@ -9395,7 +9420,7 @@ "type" : "CLASS", "meta" : { "definition" : { - "val" : "The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures.", + "val" : "The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures.", "xrefs" : [ "GOC:pdt" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon" ], @@ -9532,7 +9557,7 @@ "val" : "Reactions triggered in response to the presence of another organism that act to protect the cell or organism from damage caused by that organism.", "xrefs" : [ "GOC:dos" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "defence response incompatible interaction" @@ -9884,6 +9909,9 @@ "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/24200" + }, { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/26424" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "kmv" @@ -9986,6 +10014,29 @@ "val" : "biological_process" } ] } + }, { + "id" : "http://purl.obolibrary.org/obo/GO_0140546", + "lbl" : "defense response to symbiont", + "type" : "CLASS", + "meta" : { + "definition" : { + "val" : "Reactions triggered in response to the presence of a symbiont that act to protect or prevent damage to the host.", + "xrefs" : [ "GOC:pg" ] + }, + "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/20261" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", + "val" : "pg" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", + "val" : "2020-11-11T17:19:06Z" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "biological_process" + } ] + } }, { "id" : "http://purl.obolibrary.org/obo/GO_1901576", "lbl" : "organic substance biosynthetic process", @@ -11496,47 +11547,6 @@ "val" : "quality" } ] } - }, { - "id" : "http://purl.obolibrary.org/obo/PATO_0000068", - "lbl" : "qualitative", - "type" : "CLASS", - "meta" : { - "comments" : [ "TODO: define this or obsolete it and move children somewhere else." ], - "basicPropertyValues" : [ { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", - "val" : "quality" - } ] - } - }, { - "id" : "http://purl.obolibrary.org/obo/PATO_0000069", - "lbl" : "deviation (from_normal)", - "type" : "CLASS", - "meta" : { - "definition" : { - "val" : "A quality inhering in a bearer by virtue of the whether the bearer differs from normal or average.", - "xrefs" : [ "PATOC:GVG" ] - }, - "subsets" : [ "http://purl.obolibrary.org/obo/pato#attribute_slim" ], - "basicPropertyValues" : [ { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", - "val" : "quality" - } ] - } - }, { - "id" : "http://purl.obolibrary.org/obo/PATO_0000117", - "lbl" : "size", - "type" : "CLASS", - "meta" : { - "definition" : { - "val" : "A morphology quality inhering in a bearer by virtue of the bearer's physical magnitude.", - "xrefs" : [ "WordNet:WordNet" ] - }, - "subsets" : [ "http://purl.obolibrary.org/obo/pato#attribute_slim", "http://purl.obolibrary.org/obo/pato#scalar_slim" ], - "basicPropertyValues" : [ { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", - "val" : "quality" - } ] - } }, { "id" : "http://purl.obolibrary.org/obo/PATO_0000141", "lbl" : "structure", @@ -11585,65 +11595,6 @@ "val" : "quality" } ] } - }, { - "id" : "http://purl.obolibrary.org/obo/PATO_0000461", - "lbl" : "normal", - "type" : "CLASS", - "meta" : { - "definition" : { - "val" : "A quality inhering in a bearer by virtue of the bearer's exhibiting no deviation from normal or average.", - "xrefs" : [ "PATOC:GVG" ] - }, - "subsets" : [ "http://purl.obolibrary.org/obo/pato#abnormal_slim", "http://purl.obolibrary.org/obo/pato#mpath_slim", "http://purl.obolibrary.org/obo/pato#value_slim" ], - "synonyms" : [ { - "pred" : "hasRelatedSynonym", - "val" : "average" - } ], - "basicPropertyValues" : [ { - "pred" : "http://purl.obolibrary.org/obo/RO_0002604", - "val" : "http://purl.obolibrary.org/obo/PATO_0000460" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", - "val" : "quality" - } ] - } - }, { - "id" : "http://purl.obolibrary.org/obo/PATO_0000586", - "lbl" : "increased size", - "type" : "CLASS", - "meta" : { - "definition" : { - "val" : "A size quality which is relatively high.", - "xrefs" : [ "PATOC:GVG" ] - }, - "subsets" : [ "http://purl.obolibrary.org/obo/pato#value_slim" ], - "synonyms" : [ { - "pred" : "hasRelatedSynonym", - "val" : "big" - }, { - "pred" : "hasRelatedSynonym", - "val" : "enlarged" - }, { - "pred" : "hasRelatedSynonym", - "val" : "expanded" - }, { - "pred" : "hasRelatedSynonym", - "val" : "great" - }, { - "pred" : "hasRelatedSynonym", - "val" : "large" - } ], - "basicPropertyValues" : [ { - "pred" : "http://purl.obolibrary.org/obo/RO_0002604", - "val" : "http://purl.obolibrary.org/obo/PATO_0000587" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", - "val" : "PATO:0001202" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", - "val" : "quality" - } ] - } }, { "id" : "http://purl.obolibrary.org/obo/PATO_0000947", "lbl" : "elliptic", @@ -12184,52 +12135,6 @@ "val" : "quality" } ] } - }, { - "id" : "http://purl.obolibrary.org/obo/PATO_0002300", - "lbl" : "increased quality", - "type" : "CLASS", - "meta" : { - "definition" : { - "val" : "A quality that has a value that is increased compared to normal or average.", - "xrefs" : [ "PATOC:GVG" ] - }, - "basicPropertyValues" : [ { - "pred" : "http://purl.obolibrary.org/obo/RO_0002604", - "val" : "http://purl.obolibrary.org/obo/PATO_0002301" - }, { - "pred" : "http://purl.org/dc/terms/contributor", - "val" : "https://orcid.org/0000-0002-2061-091X" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", - "val" : "2011-06-16T06:39:43Z" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", - "val" : "quality" - } ] - } - }, { - "id" : "http://purl.obolibrary.org/obo/PATO_0002305", - "lbl" : "increased object quality", - "type" : "CLASS", - "meta" : { - "definition" : { - "val" : "A quality of an object that has a value that is increased compared to normal or average.", - "xrefs" : [ "PATOC:GVG" ] - }, - "basicPropertyValues" : [ { - "pred" : "http://purl.obolibrary.org/obo/RO_0002604", - "val" : "http://purl.obolibrary.org/obo/PATO_0002303" - }, { - "pred" : "http://purl.org/dc/terms/contributor", - "val" : "https://orcid.org/0000-0002-2061-091X" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", - "val" : "2011-06-16T06:54:01Z" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", - "val" : "quality" - } ] - } }, { "id" : "http://purl.obolibrary.org/obo/PATO_0002309", "lbl" : "fiber shaped", @@ -12354,6 +12259,28 @@ "val" : "quality" } ] } + }, { + "id" : "http://purl.obolibrary.org/obo/PATO_0040072", + "lbl" : "high nuclear/cytoplasmic ratio", + "type" : "CLASS", + "meta" : { + "definition" : { + "val" : "A quality inhering in a cell by virtue of the cell having a high nuclear/cytoplasmic ratio.", + "xrefs" : [ "Wikipedia:NC_ratio&oldid=931936284", "http://lymerick.net/blood-cells.pdf" ] + }, + "comments" : [ "A high nuclear/cytolasmic ratio is 70% or higher." ], + "synonyms" : [ { + "pred" : "hasExactSynonym", + "val" : "high N:C ratio" + } ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", + "val" : "http://orcid.org/0000-0001-5208-3432" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "quality" + } ] + } }, { "id" : "http://purl.obolibrary.org/obo/PATO_0070044", "lbl" : "anatomical structure quality", @@ -16230,6 +16157,9 @@ "val" : "inverse of develops from" }, "subsets" : [ "http://purl.obolibrary.org/obo/RO_0002259" ], + "xrefs" : [ { + "val" : "RO:0002203" + } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000114", "val" : "http://purl.obolibrary.org/obo/IAO_0000125" @@ -16242,6 +16172,12 @@ }, { "pred" : "http://purl.obolibrary.org/obo/IAO_0000117", "val" : "https://orcid.org/0000-0003-1980-3228" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "uberon" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#shorthand", + "val" : "develops_into" } ] } }, { @@ -20706,7 +20642,7 @@ "val" : "sinew", "xrefs" : [ "Wikipedia:Tendon" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "tendo", "xrefs" : [ "Wikipedia:Tendon" ] @@ -21456,7 +21392,7 @@ "val" : "zygote", "xrefs" : [ "VHOG:0000745" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "zygotum", "xrefs" : [ "Wikipedia:Zygote" ] @@ -21733,7 +21669,7 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#efo_slim", "http://purl.obolibrary.org/obo/uberon/core#major_organ", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "regio oralis", "xrefs" : [ "BTO:0004698", "FMA:49184", "FMA:TA" ] @@ -21741,7 +21677,7 @@ "pred" : "hasNarrowSynonym", "val" : "adult mouth" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "cavital oralis", "xrefs" : [ "Wikipedia:Mouth" ] @@ -22640,8 +22576,6 @@ "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#common_anatomy", "http://purl.obolibrary.org/obo/uberon/core#upper_level" ], "xrefs" : [ { "val" : "FBbt:00007277" - }, { - "val" : "IDOMAL:0002461" }, { "val" : "VHOG:0001737" } ], @@ -23890,7 +23824,7 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "systema cardiovasculare", "xrefs" : [ "Wikipedia:Circulatory_system" ] @@ -23899,6 +23833,8 @@ "val" : "AAO:0000959" }, { "val" : "CALOHA:TS-2103" + }, { + "val" : "MESH:D002319" }, { "val" : "VHOG:0001248" }, { @@ -23956,7 +23892,7 @@ "pred" : "hasExactSynonym", "val" : "musculature" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "musculi", "xrefs" : [ "FMA:32558", "FMA:TA" ] @@ -24030,7 +23966,7 @@ "val" : "The nervous system is an organ system containing predominantly neuron and glial cells. In bilaterally symmetrical organism, it is arranged in a network of tree-like structures connected to a central body. The main functions of the nervous system are to regulate and control body functions, and to receive sensory input, process this information, and generate behavior [CUMBO].", "xrefs" : [ "BIRNLEX:844", "ISBN:0-14-051288-8", "ISBN:3110148986", "NLM:nervous+system", "WB:rynl", "Wikipedia:Nervous_system", "ZFIN:curator" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#cumbo", "http://purl.obolibrary.org/obo/uberon/core#efo_slim", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], + "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#cumbo", "http://purl.obolibrary.org/obo/uberon/core#efo_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "neurological system", @@ -24040,7 +23976,7 @@ "val" : "nerve net", "xrefs" : [ "Wikipedia:Nerve_net" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "systema nervosum", "xrefs" : [ "Wikipedia:Nervous_system" ] @@ -24103,6 +24039,9 @@ "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_6040" + }, { + "pred" : "http://purl.obolibrary.org/obo/RO_0002175", + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" }, { "pred" : "http://purl.obolibrary.org/obo/UBPROP_0000001", "val" : "A regulatory system of the body that consists of neurons and neuroglial cells. The nervous system is divided into two parts, the central nervous system (CNS) and the peripheral nervous system (PNS). (Source: BioGlossary, www.Biology-Text.com)[TAO]" @@ -24138,13 +24077,13 @@ "val" : "The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the neural tube derivatives: the brain and spinal cord. In invertebrates it includes central ganglia plus nerve cord.", "xrefs" : [ "GO:0021551", "http://www.frontiersinzoology.com/content/7/1/29", "https://sourceforge.net/p/geneontology/ontology-requests/11422/" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#cumbo", "http://purl.obolibrary.org/obo/uberon/core#efo_slim", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], + "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#cumbo", "http://purl.obolibrary.org/obo/uberon/core#efo_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], "synonyms" : [ { "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003000", "pred" : "hasExactSynonym", "val" : "CNS" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "systema nervosum centrale", "xrefs" : [ "FMA:55675", "FMA:TA" ] @@ -24215,6 +24154,9 @@ "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099" + }, { + "pred" : "http://purl.obolibrary.org/obo/RO_0002175", + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" }, { "pred" : "http://purl.obolibrary.org/obo/UBPROP_0000001", "val" : "Part of the nervous system which includes the brain and spinal cord.[AAO]" @@ -24243,7 +24185,7 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#efo_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "organa sensuum", "xrefs" : [ "FMA:75259", "FMA:TA" ] @@ -24267,7 +24209,7 @@ "val" : "sensory systems", "xrefs" : [ "TAO:0000282" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "organa sensuum", "xrefs" : [ "Wikipedia:Sensory_system" ] @@ -24345,7 +24287,7 @@ "pred" : "hasRelatedSynonym", "val" : "presumptive central nervous system" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "tubus neuralis", "xrefs" : [ "Wikipedia:Neural_tube" ] @@ -24911,6 +24853,8 @@ "val" : "FMA:45615" }, { "val" : "MA:0000917" + }, { + "val" : "MESH:D041981" }, { "val" : "NCIT:C34082" }, { @@ -25393,7 +25337,7 @@ "val" : "notocord", "xrefs" : [ "ZFA:0000135" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "notochorda", "xrefs" : [ "Wikipedia:Notochord" ] @@ -25506,7 +25450,7 @@ "pred" : "hasRelatedSynonym", "val" : "somitic mesoderm" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "somitus", "xrefs" : [ "Wikipedia:Somite" ] @@ -25641,7 +25585,7 @@ "val" : "NC", "xrefs" : [ "XAO:0000048" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "crista neuralis", "xrefs" : [ "Wikipedia:Neural_crest" ] @@ -25735,7 +25679,7 @@ "pred" : "hasExactSynonym", "val" : "neuroectoderm" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "epithelium tubi neuralis; neuroectoderma", "xrefs" : [ "Wikipedia:Neuroectoderm" ] @@ -25818,7 +25762,7 @@ "val" : "ducted gland", "xrefs" : [ "AEO:0000097" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "glandula exocrina", "xrefs" : [ "Wikipedia:Exocrine_gland" ] @@ -25880,7 +25824,7 @@ "val" : "ductless gland", "xrefs" : [ "Wikipedia:Ductless_gland" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "glandulae endocrinae", "xrefs" : [ "Wikipedia:Endocrine_gland" ] @@ -25931,12 +25875,12 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#efo_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "medulla ossea", "xrefs" : [ "BTO:0000141", "FMA:9608" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "medulla ossium", "xrefs" : [ "BTO:0000141", "Wikipedia:Bone_marrow" ] @@ -26391,7 +26335,7 @@ "val" : "Druese", "xrefs" : [ "BTO:0000522" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "glandula", "xrefs" : [ "BTO:0000522", "Wikipedia:Gland" ] @@ -26477,7 +26421,7 @@ "val" : "ectoblast", "xrefs" : [ "MP:0003886" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "epiblastus", "xrefs" : [ "Wikipedia:Epiblast" ] @@ -26736,7 +26680,7 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "lamina neuralis", "xrefs" : [ "Wikipedia:Neural_plate" ] @@ -26814,7 +26758,7 @@ "val" : "somitic mesoderm", "xrefs" : [ "ISBN:9780878932504" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "mesoderma paraxiale", "xrefs" : [ "Wikipedia:Paraxial_mesoderm" ] @@ -26890,7 +26834,7 @@ "val" : "lateral plate mesenchyme", "xrefs" : [ "EHDAA2:0000919" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "mesoderma laminae lateralis", "xrefs" : [ "Wikipedia:Lateral_plate_mesoderm" ] @@ -26973,7 +26917,7 @@ "pred" : "hasRelatedSynonym", "val" : "myotomes" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "myotomus", "xrefs" : [ "Wikipedia:Myotome" ] @@ -27102,7 +27046,7 @@ "pred" : "hasExactSynonym", "val" : "portion of mesenchyme tissue" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "mesenchyma", "xrefs" : [ "Wikipedia:Mesenchyme" ] @@ -28159,7 +28103,7 @@ "val" : "basement membrane of connective tissue", "xrefs" : [ "FMA:63872" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "membrana basalis", "xrefs" : [ "Wikipedia:Basement_membrane" ] @@ -28908,7 +28852,7 @@ "val" : "A subdivision of an anatomical system.", "xrefs" : [ "http://orcid.org/0000-0002-6601-2165" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#common_anatomy", "http://purl.obolibrary.org/obo/uberon/core#upper_level" ], + "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#common_anatomy", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#upper_level" ], "xrefs" : [ { "val" : "FBbt:00007330" }, { @@ -28925,6 +28869,9 @@ }, { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_4751" + }, { + "pred" : "http://purl.obolibrary.org/obo/RO_0002175", + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "uberon" @@ -29257,7 +29204,7 @@ "val" : "The region of the organism associated with the visceral organs.", "xrefs" : [ "AEO:0000103" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#non_informative" ], + "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#non_informative" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "body", @@ -29277,9 +29224,6 @@ "val" : "FMA:231424" } ], "basicPropertyValues" : [ { - "pred" : "http://purl.obolibrary.org/obo/RO_0002175", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" - }, { "pred" : "http://purl.obolibrary.org/obo/UBPROP_0000001", "val" : "Cardinal body part, which consists of a maximal set of diverse subclasses of organ and organ part spatially associated with the vertebral column and ribcage. Examples: There is only one body proper[FMA:231424]." }, { @@ -29296,6 +29240,7 @@ "val" : "A muscle organ that consists of skeletal muscle tissue ensheathed in epimysium, that develops from myotome and that is innervated by some somatic motor neuron. Skeletal muscles are typically attached (via a tendon) to a bone but there are exceptions (e.g. intrinsic tongue muscles).", "xrefs" : [ "GOC:dos" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "skeletal muscle" @@ -29340,6 +29285,9 @@ "val" : "ZFA:0005277" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/RO_0002175", + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "uberon" } ] @@ -29567,7 +29515,7 @@ "lbl" : "skeletal musculature", "type" : "CLASS", "meta" : { - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#grouping_class" ], + "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#grouping_class", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { "val" : "EHDAA2:0001842" }, { @@ -29578,6 +29526,9 @@ "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000116", "val" : "Added for consistency with MA EMAPA and EHDAA2. See https://github.com/obophenotype/mouse-anatomy-ontology/issues/104" + }, { + "pred" : "http://purl.obolibrary.org/obo/RO_0002175", + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "uberon" @@ -29816,8 +29767,10 @@ "val" : "OBSOLETE A relation between a cell and molecule or complex such that every instance of the cell has a high number of instances of that molecule expressed on the cell surface. For the formal definition, see Masci et al (PMID:19243617).", "xrefs" : [ "PMID:19243617" ] }, - "comments" : [ "Replaced with RO:0015015, see https://github.com/obophenotype/cell-ontology/issues/1481" ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/obophenotype/cell-ontology/issues/1481" + }, { "pred" : "http://purl.obolibrary.org/obo/IAO_0100001", "val" : "http://purl.obolibrary.org/obo/RO_0015015" } ], @@ -29832,8 +29785,10 @@ "val" : "OBSOLETE A relation between a cell and molecule or complex such that every instance of the cell has a low number of instances of that molecule expressed on the cell surface. For the formal definition, see Masci et al (PMID:19243617).", "xrefs" : [ "PMID:19243617" ] }, - "comments" : [ "Replaced with RO:0015016, see https://github.com/obophenotype/cell-ontology/issues/1481" ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/obophenotype/cell-ontology/issues/1481" + }, { "pred" : "http://purl.obolibrary.org/obo/IAO_0100001", "val" : "http://purl.obolibrary.org/obo/RO_0015016" } ], @@ -30063,13 +30018,12 @@ "lbl" : "transitively anteriorly connected to", "type" : "PROPERTY", "meta" : { - "definition" : { - "val" : ".", - "xrefs" : [ "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" ] - }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "uberon" + }, { + "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", + "val" : "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" } ] } }, { @@ -30077,13 +30031,12 @@ "lbl" : "transitively distally connected to", "type" : "PROPERTY", "meta" : { - "definition" : { - "val" : ".", - "xrefs" : [ "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" ] - }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "uberon" + }, { + "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", + "val" : "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" } ] } }, { @@ -30091,13 +30044,12 @@ "lbl" : "transitively proximally connected to", "type" : "PROPERTY", "meta" : { - "definition" : { - "val" : ".", - "xrefs" : [ "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" ] - }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "uberon" + }, { + "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", + "val" : "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" } ] } }, { @@ -31294,11 +31246,11 @@ }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000542", "pred" : "http://purl.obolibrary.org/obo/BFO_0000051", - "obj" : "http://purl.obolibrary.org/obo/CL_0017505" + "obj" : "http://purl.obolibrary.org/obo/GO_0000792" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000542", - "pred" : "http://purl.obolibrary.org/obo/BFO_0000051", - "obj" : "http://purl.obolibrary.org/obo/GO_0000792" + "pred" : "http://purl.obolibrary.org/obo/RO_0000053", + "obj" : "http://purl.obolibrary.org/obo/PATO_0040072" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000542", "pred" : "http://purl.obolibrary.org/obo/RO_0002202", @@ -32221,14 +32173,6 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0017503", "pred" : "http://purl.obolibrary.org/obo/RO_0000053", "obj" : "http://purl.obolibrary.org/obo/PATO_0002094" - }, { - "sub" : "http://purl.obolibrary.org/obo/CL_0017505", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/GO_0005634" - }, { - "sub" : "http://purl.obolibrary.org/obo/CL_0017505", - "pred" : "http://purl.obolibrary.org/obo/RO_0000053", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000586" }, { "sub" : "http://purl.obolibrary.org/obo/CL_1001610", "pred" : "is_a", @@ -33678,7 +33622,7 @@ }, { "sub" : "http://purl.obolibrary.org/obo/GO_0045087", "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/GO_0098542" + "obj" : "http://purl.obolibrary.org/obo/GO_0140546" }, { "sub" : "http://purl.obolibrary.org/obo/GO_0045202", "pred" : "is_a", @@ -34427,6 +34371,10 @@ "sub" : "http://purl.obolibrary.org/obo/GO_0140352", "pred" : "http://purl.obolibrary.org/obo/RO_0002339", "obj" : "http://purl.obolibrary.org/obo/GO_0005576" + }, { + "sub" : "http://purl.obolibrary.org/obo/GO_0140546", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/GO_0098542" }, { "sub" : "http://purl.obolibrary.org/obo/GO_1901576", "pred" : "is_a", @@ -34615,18 +34563,6 @@ "sub" : "http://purl.obolibrary.org/obo/PATO_0000052", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/PATO_0000051" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0000068", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000001" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0000069", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000068" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0000117", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000051" }, { "sub" : "http://purl.obolibrary.org/obo/PATO_0000141", "pred" : "is_a", @@ -34635,18 +34571,6 @@ "sub" : "http://purl.obolibrary.org/obo/PATO_0000411", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/PATO_0000947" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0000461", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000068" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0000586", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000117" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0000586", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0002305" }, { "sub" : "http://purl.obolibrary.org/obo/PATO_0000947", "pred" : "is_a", @@ -34767,22 +34691,6 @@ "sub" : "http://purl.obolibrary.org/obo/PATO_0002299", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/PATO_0002078" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0002300", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000069" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0002300", - "pred" : "http://purl.obolibrary.org/obo/RO_0015007", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000461" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0002305", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0001241" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0002305", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0002300" }, { "sub" : "http://purl.obolibrary.org/obo/PATO_0002309", "pred" : "is_a", @@ -34807,6 +34715,10 @@ "sub" : "http://purl.obolibrary.org/obo/PATO_0015006", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/PATO_0000141" + }, { + "sub" : "http://purl.obolibrary.org/obo/PATO_0040072", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/PATO_0001396" }, { "sub" : "http://purl.obolibrary.org/obo/PATO_0070044", "pred" : "is_a", @@ -39846,15 +39758,15 @@ "restrictions" : [ { "propertyId" : "http://purl.obolibrary.org/obo/BFO_0000051", "fillerId" : "http://purl.obolibrary.org/obo/CL_0017500" - }, { - "propertyId" : "http://purl.obolibrary.org/obo/BFO_0000051", - "fillerId" : "http://purl.obolibrary.org/obo/CL_0017505" }, { "propertyId" : "http://purl.obolibrary.org/obo/BFO_0000051", "fillerId" : "http://purl.obolibrary.org/obo/GO_0000792" }, { "propertyId" : "http://purl.obolibrary.org/obo/RO_0000053", "fillerId" : "http://purl.obolibrary.org/obo/PATO_0001407" + }, { + "propertyId" : "http://purl.obolibrary.org/obo/RO_0000053", + "fillerId" : "http://purl.obolibrary.org/obo/PATO_0040072" } ] }, { "definedClassId" : "http://purl.obolibrary.org/obo/CL_0000557", @@ -40375,13 +40287,6 @@ "propertyId" : "http://purl.obolibrary.org/obo/RO_0000053", "fillerId" : "http://purl.obolibrary.org/obo/PATO_0002094" } ] - }, { - "definedClassId" : "http://purl.obolibrary.org/obo/CL_0017505", - "genusIds" : [ "http://purl.obolibrary.org/obo/GO_0005634" ], - "restrictions" : [ { - "propertyId" : "http://purl.obolibrary.org/obo/RO_0000053", - "fillerId" : "http://purl.obolibrary.org/obo/PATO_0000586" - } ] }, { "definedClassId" : "http://purl.obolibrary.org/obo/CL_1001610", "genusIds" : [ "http://purl.obolibrary.org/obo/CL_0000988" ], @@ -41223,27 +41128,6 @@ "propertyId" : "http://purl.obolibrary.org/obo/RO_0002211", "fillerId" : "http://purl.obolibrary.org/obo/GO_0007275" } ] - }, { - "definedClassId" : "http://purl.obolibrary.org/obo/PATO_0000586", - "genusIds" : [ "http://purl.obolibrary.org/obo/PATO_0000117" ], - "restrictions" : [ { - "propertyId" : "http://purl.obolibrary.org/obo/RO_0015007", - "fillerId" : "http://purl.obolibrary.org/obo/PATO_0000461" - } ] - }, { - "definedClassId" : "http://purl.obolibrary.org/obo/PATO_0002300", - "genusIds" : [ "http://purl.obolibrary.org/obo/PATO_0000001" ], - "restrictions" : [ { - "propertyId" : "http://purl.obolibrary.org/obo/RO_0015007", - "fillerId" : "http://purl.obolibrary.org/obo/PATO_0000461" - } ] - }, { - "definedClassId" : "http://purl.obolibrary.org/obo/PATO_0002305", - "genusIds" : [ "http://purl.obolibrary.org/obo/PATO_0001241" ], - "restrictions" : [ { - "propertyId" : "http://purl.obolibrary.org/obo/RO_0015007", - "fillerId" : "http://purl.obolibrary.org/obo/PATO_0000461" - } ] }, { "definedClassId" : "http://purl.obolibrary.org/obo/PR_000029032", "genusIds" : [ "http://purl.obolibrary.org/obo/PR_000000001" ], diff --git a/src/ontology/subsets/general_cell_types_upper_slim.obo b/src/ontology/subsets/general_cell_types_upper_slim.obo index 824b27a28..bf1c7bcd8 100644 --- a/src/ontology/subsets/general_cell_types_upper_slim.obo +++ b/src/ontology/subsets/general_cell_types_upper_slim.obo @@ -1,5 +1,5 @@ format-version: 1.2 -data-version: cl/releases/2024-01-04/subsets/general_cell_types_upper_slim.owl +data-version: cl/releases/2024-02-13/subsets/general_cell_types_upper_slim.owl subsetdef: abnormal_slim "" subsetdef: added_for_HCA "" subsetdef: attribute_slim "" @@ -31,6 +31,7 @@ subsetdef: goslim_mouse "" subsetdef: goslim_pir "" subsetdef: goslim_plant "" subsetdef: goslim_pombe "" +subsetdef: goslim_prokaryote "" subsetdef: goslim_synapse "" subsetdef: goslim_yeast "" subsetdef: grouping_class "" @@ -49,7 +50,6 @@ subsetdef: non_informative "" subsetdef: organ_slim "" subsetdef: pheno_slim "" subsetdef: phenotype_rcn "" -subsetdef: prokaryote_subset "" subsetdef: ro-eco "" subsetdef: RO:0002259 "" subsetdef: scalar_slim "" @@ -62,7 +62,6 @@ subsetdef: vertebrate_core "" synonymtypedef: blast_name "" synonymtypedef: COMPARATIVE_PREFERRED "" synonymtypedef: DEPRECATED "" -synonymtypedef: DUBIOUS "" synonymtypedef: equivalent_name "" synonymtypedef: genbank_common_name "" synonymtypedef: Gene-based "" @@ -71,13 +70,14 @@ synonymtypedef: HUMAN_PREFERRED "" synonymtypedef: HUMAN_PREFERRED "preferred term when talking about an instance of this class in Homo sapiens" synonymtypedef: in_part "" synonymtypedef: INCONSISTENT "" -synonymtypedef: LATIN "" synonymtypedef: LATIN "latin term" synonymtypedef: MISSPELLING "a mis-spelling that is in common use and thus recorded" synonymtypedef: NON_MAMMAL "" synonymtypedef: OMO:0003000 "abbreviation" +synonymtypedef: OMO:0003002 "" synonymtypedef: OMO:0003003 "" synonymtypedef: OMO:0003004 "plural form" +synonymtypedef: OMO:0003011 "" synonymtypedef: PENDING_REVIEW "" synonymtypedef: PLURAL "plural term" synonymtypedef: PRO-short-label "" @@ -88,7 +88,7 @@ synonymtypedef: synonym "" synonymtypedef: SYSTEMATIC "" synonymtypedef: systematic_synonym "" ontology: cl/subsets/general_cell_types_upper_slim -property_value: owl:versionInfo "2024-01-04" xsd:string +property_value: owl:versionInfo "2024-02-13" xsd:string [Term] id: BFO:0000002 @@ -144,6 +144,7 @@ id: CL:0000000 name: cell def: "A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane." [CARO:mah] comment: The definition of cell is intended to represent all cells, and thus a cell is defined as a material entity and not an anatomical structure, which implies that it is part of an organism (or the entirety of one). +subset: cellxgene_subset subset: ubprop:upper_level xref: CALOHA:TS-2035 xref: FBbt:00007002 @@ -163,6 +164,7 @@ relationship: only_in_taxon NCBITaxon:131567 ! cellular organisms [Term] id: CL:0000006 name: neuronal receptor cell +subset: cellxgene_subset synonym: "neuronal receptor cell (sensu Animalia)" EXACT [] is_a: CL:0000101 ! sensory neuron is_a: CL:0000197 ! sensory receptor cell @@ -181,6 +183,7 @@ id: CL:0000034 name: stem cell def: "A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells." [GOC:tfm, MESH:D013234] comment: This term applies to metazoan. For plant stem cells, consider using PO:0004011 ‘initial cell’ or its parent PO:0004010 ‘meristematic cell’. +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "animal stem cell" EXACT [] @@ -199,6 +202,7 @@ name: hematopoietic stem cell def: "A stem cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system. Hematopoietic stem cells lack cell markers of effector cells (lin-negative). Lin-negative is defined by lacking one or more of the following cell surface markers: CD2, CD3 epsilon, CD4, CD5 ,CD8 alpha chain, CD11b, CD14, CD19, CD20, CD56, ly6G, ter119." [GOC:add, GOC:dsd, GOC:tfm, http://en.wikipedia.org/wiki/Hematopoietic_stem_cell, PMID:19022770] comment: Markers differ between species, and two sets of markers have been described for mice. HSCs are reportedly CD34-positive, CD45-positive, CD48-negative, CD150-positive, CD133-positive, and CD244-negative. subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "blood forming stem cell" EXACT [] synonym: "colony forming unit hematopoietic" RELATED [] @@ -299,6 +303,7 @@ id: CL:0000049 name: common myeloid progenitor def: "A progenitor cell committed to myeloid lineage, including the megakaryocyte and erythroid lineages." [GOC:add, ISBN:0878932437, MESH:D023461] comment: This cell type is intended to be compatible with any vertebrate common myeloid progenitor. For mammalian CMP known to be CD34-positive, please use the term 'common myeloid progenitor, CD34-positive' (CL_0001059). +subset: cellxgene_subset subset: human_reference_atlas synonym: "CFU-GEMM" RELATED OMO:0003000 [ISBN:0878932437] synonym: "CFU-S" RELATED OMO:0003000 [ISBN:0878932437] @@ -319,6 +324,7 @@ id: CL:0000051 name: common lymphoid progenitor def: "A oligopotent progenitor cell committed to the lymphoid lineage." [GOC:add, GOC:dsd, GOC:tfm, PMID:10407577, PMID:16551251] comment: CLP are CD7-positive, CD10-positive, CD19-negative, CD34-positive, CD45RA-positive, CD79a-negative, CD127-positive, AA4.1-positive, RAG-negative, Sca-1-low, sIgM-negative, sIgD-negative, TdT-negative, Vpre-B-negative, and pre-BCR-negative. Expression of transcription factors include E2A-positive, EBF-positive, Ikaros-negative, PU.1-negative, and Pax5-negative. +subset: cellxgene_subset subset: human_reference_atlas synonym: "CLP" RELATED OMO:0003000 [] synonym: "committed lymphopoietic stem cell" RELATED [] @@ -350,6 +356,7 @@ id: CL:0000055 name: non-terminally differentiated cell def: "A precursor cell with a limited number of potential fates." [SANBI:mhl] comment: define using PATO mulit-potent or oligopotent? +subset: cellxgene_subset synonym: "blast cell" EXACT [] xref: BTO:0000125 xref: FMA:84782 @@ -371,6 +378,7 @@ id: CL:0000057 name: fibroblast def: "A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped." [http://en.wikipedia.org/wiki/Fibroblast, ISBN:0517223651, MESH:D005347] comment: These cells may be vimentin-positive, fibronectin-positive, fsp1-positive, MMP-1-positive, collagen I-positive, collagen III-positive, and alpha-SMA-negative. +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas xref: BTO:0000452 @@ -386,6 +394,7 @@ relationship: present_in_taxon NCBITaxon:9606 id: CL:0000066 name: epithelial cell def: "A cell that is usually found in a two-dimensional sheet with a free surface. The cell has a cytoskeleton that allows for tight cell to cell contact and for cell polarity where apical part is directed towards the lumen and the basal part to the basal lamina." [FB:ma, GOC:tfm, MESH:D004847] +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "epitheliocyte" EXACT [] @@ -405,6 +414,7 @@ property_value: depiction "https://www.swissbiopics.org/api/image/Epithelial_cel id: CL:0000075 name: columnar/cuboidal epithelial cell def: "A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube." [GO:0002065, https://orcid.org/0000-0001-5208-3432] +subset: cellxgene_subset subset: human_reference_atlas is_a: CL:0000066 ! epithelial cell relationship: present_in_taxon NCBITaxon:9606 @@ -413,6 +423,7 @@ relationship: present_in_taxon NCBITaxon:9606 id: CL:0000081 name: blood cell def: "A cell found predominately in the blood." [GOC:add, GOC:tfm] +subset: cellxgene_subset subset: general_cell_types_upper_slim xref: FMA:62844 xref: MESH:D001773 @@ -425,6 +436,7 @@ relationship: capable_of GO:0008015 ! blood circulation id: CL:0000084 name: T cell def: "A type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex." [GOC:add, GOC:tfm, ISBN:0781735149] +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "immature T cell" RELATED [] @@ -450,6 +462,7 @@ id: CL:0000092 name: osteoclast def: "A specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue, which typically differentiates from monocytes. This cell has the following markers: tartrate-resistant acid phosphatase type 5-positive, PU.1-positive, c-fos-positive, nuclear factor NF-kappa-B p100 subunit-positive, tumor necrosis factor receptor superfamily member 11A-positive and macrophage colony-stimulating factor 1 receptor-positive." [GO_REF:0000031, GOC:add, GOC:tfm, ISBN:0781735149, PMID:10428500, PMID:15055519, PMID:17380158] comment: Morphology: Highly vesicular; markers: Surface: RANK, cFMS (MCSF receptor); Secreted: cathepsin K and TRAP (tartate resistant acid phosphatase); transcription factors: PU.1, cFOS, MITF, NFkB (p52); role or process: tissue remodelling: bone resorption; lineage: hematopoietic, myeloid. +subset: cellxgene_subset synonym: "chondroclast" RELATED [] xref: BTO:0000968 xref: CALOHA:TS-0721 @@ -483,6 +496,7 @@ relationship: RO:0002104 PR:000002062 ! has plasma membrane part macrophage colo id: CL:0000094 name: granulocyte def: "A leukocyte with abundant granules in the cytoplasm." [GOC:amm, GOC:tfm, http://en.wikipedia.org/wiki/Granulocyte, MESH:D006098] +subset: cellxgene_subset subset: human_reference_atlas synonym: "granular leucocyte" EXACT [] synonym: "granular leukocyte" EXACT [] @@ -517,6 +531,7 @@ relationship: RO:0002104 PR:000001969 ! has plasma membrane part urokinase plasm [Term] id: CL:0000095 name: neuron associated cell +subset: cellxgene_subset is_a: CL:0002319 ! neural cell relationship: develops_from CL:0000133 ! neurectodermal cell @@ -524,6 +539,7 @@ relationship: develops_from CL:0000133 ! neurectodermal cell id: CL:0000100 name: motor neuron def: "An efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes or inhibits movement." [MESH:D009046, PMID:16875686] +subset: cellxgene_subset subset: human_reference_atlas synonym: "motoneuron" EXACT [] xref: BTO:0000312 @@ -551,6 +567,7 @@ relationship: capable_of GO:0050906 ! detection of stimulus involved in sensory id: CL:0000113 name: mononuclear phagocyte def: "A vertebrate phagocyte with a single nucleus." [GOC:add, GOC:tfm, ISBN:0781735149] +subset: cellxgene_subset subset: human_reference_atlas xref: BTO:0001433 is_a: CL:0000518 {is_inferred="true"} ! phagocyte (sensu Vertebrata) @@ -564,6 +581,7 @@ id: CL:0000125 name: glial cell def: "A non-neuronal cell of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu. Guide neuronal migration during development, and exchange metabolites with neurons." [MESH:D009457] comment: Not all glial cells develop from glioblasts, with microglia developing from the mesoderm instead. See https://github.com/obophenotype/cell-ontology/issues/1571 +subset: cellxgene_subset subset: general_cell_types_upper_slim synonym: "neuroglia" RELATED [] synonym: "neuroglial cell" EXACT [] @@ -585,6 +603,7 @@ id: CL:0000134 name: mesenchymal stem cell def: "A connective tissue cell that normally gives rise to other cells that are organized as three-dimensional masses. In humans, this cell type is CD73-positive, CD90-positive, CD105-positive, CD45-negative, CD34-negative, and MHCII-negative. They may further differentiate into osteoblasts, adipocytes, myocytes, neurons, or chondroblasts in vitro. Originally described as residing in the bone marrow, this cell type is now known to reside in many, if not all, adult organs." [FB:ma, GOC:dsd, http://en.wikipedia.org/wiki/Mesenchymal_stem_cell, http://www.copewithcytokines.de/cope.cgi?key=mesenchymal%20stem%20cells, PMCID:PMC2613570, PMID:10102814, PMID:16923606, PMID:17986482, PMID:19960544] comment: Many but not all mesenchymal cells derive from the mesoderm. MSCs are reportedly CD3-negative, CD4-negative, CD5-negative, CD8-negative, CD11a-negative, CD11b-negative, CD14-negative, CD19-negative, CD29-positive, CD31-negative, CD34-negative, CD38-negative, CD40-negative, CD44-positive, CD45-negative, CD49-positive, CD54-positive, CD66b-negative, CD79a-negative, CD80-negative, CD102-positive, CD106-positive, CD117-positive, CD121a-positive, CD121b-positive, CD123-positive, CD124-positive, CD133-negative, CD146-positive, CD166-positive, CD271-positive, B220-negative, Gr1-negative, MHCI-positive, MHCII-negative, SSEA4-negative, sca1-positive, Ter119-negative, and glycophorin A-negative. Cultured MSCs are capable of producing stem cell factor, IL7, IL8, IL11, TGF-beta, cofilin, galectin-1, laminin-receptor 1, cyclophilin A, and MMP-2. +subset: cellxgene_subset synonym: "BMSC" RELATED OMO:0003000 [] synonym: "bone marrow stromal cells" NARROW [] synonym: "CFU-F" RELATED OMO:0003000 [] @@ -608,6 +627,7 @@ property_value: seeAlso "https://github.com/obophenotype/cell-ontology/issues/47 id: CL:0000136 name: adipocyte def: "A fat-storing cell found mostly in the abdominal cavity and subcutaneous tissue of mammals. Fat is usually stored in the form of triglycerides." [MESH:D017667] +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "adipose cell" EXACT [] @@ -626,6 +646,7 @@ name: professional antigen presenting cell def: "A cell capable of processing and presenting lipid and protein antigens to T cells in order to initiate an immune response." [GOC:add, ISBN:0781735149] comment: Note change of name; nearly all somatic cells can present antigens to T cells via MHC Class I complexes leading to effector responses, but professional antigen presenting cells constitutively express MHC Class II as well as costimulatory molecules, and thus can initiate immune responses via T cells. subset: blood_and_immune_upper_slim +subset: cellxgene_subset synonym: "APC" RELATED OMO:0003000 [] is_a: CL:0000738 ! leukocyte intersection_of: CL:0000738 ! leukocyte @@ -645,6 +666,7 @@ is_a: CL:0000325 ! stuff accumulating cell id: CL:0000148 name: melanocyte def: "A pigment cell derived from the neural crest. Contains melanin-filled pigment granules, which gives a brown to black appearance." [SANBI:mhl] +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "melanophore" NARROW [] @@ -671,6 +693,7 @@ is_a: CL:0000147 ! pigment cell id: CL:0000151 name: secretory cell def: "A cell that specializes in controlled release of one or more substances." [GOC:tfm, ISBN:0721662544] +subset: cellxgene_subset xref: BTO:0003659 xref: FMA:86916 is_a: CL:0000000 ! cell @@ -693,6 +716,7 @@ relationship: part_of UBERON:0002365 ! exocrine gland id: CL:0000163 name: endocrine cell def: "A cell of an endocrine gland, ductless glands that secrete substances which are released directly into the circulation and which influence metabolism and other body functions." [MESH:D055098] +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "endocrinocyte" EXACT [] @@ -705,12 +729,14 @@ relationship: present_in_taxon NCBITaxon:9606 id: CL:0000183 name: contractile cell def: "A cell whose primary function is to shorten." [FB:ma] +subset: cellxgene_subset is_a: CL:0000000 ! cell [Term] id: CL:0000187 name: muscle cell def: "A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns." [MESH:D032342] +subset: cellxgene_subset synonym: "muscle fiber" EXACT [] synonym: "myocyte" EXACT [] xref: BTO:0000888 @@ -728,6 +754,7 @@ property_value: depiction "https://www.swissbiopics.org/api/image/Muscle_cells.s id: CL:0000188 name: cell of skeletal muscle def: "A somatic cell located in skeletal muscle." [GOC:tfm] +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "skeletal muscle cell" EXACT [] @@ -744,6 +771,7 @@ relationship: present_in_taxon NCBITaxon:9606 id: CL:0000192 name: smooth muscle cell def: "A non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels. They develop from specialized myoblasts (smooth muscle myoblast)." [http://en.wikipedia.org/wiki/Smooth_muscle_cell, MESH:D032389, PMID:9315361] +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "myocytes, smooth muscle" EXACT [MESH:D032389] @@ -775,6 +803,7 @@ relationship: part_of UBERON:0001032 ! sensory system id: CL:0000210 name: photoreceptor cell def: "A cell specialized to detect and transduce light." [MESH:D010786] +subset: cellxgene_subset xref: BTO:0001060 xref: CALOHA:TS-0868 xref: FMA:86740 @@ -812,6 +841,7 @@ relationship: part_of UBERON:0000924 ! ectoderm id: CL:0000222 name: mesodermal cell def: "A cell of the middle germ layer of the embryo." [MESH:D008648] +subset: cellxgene_subset synonym: "mesoblast" EXACT [] synonym: "mesoderm cell" EXACT [] xref: FMA:72554 @@ -854,6 +884,7 @@ relationship: bearer_of PATO:0001908 ! multinucleate id: CL:0000234 name: phagocyte def: "Any cell capable of ingesting particulate matter via phagocytosis." [GOC:add, ISBN:0721601464] +subset: cellxgene_subset xref: BTO:0001044 xref: FMA:83806 xref: MESH:D010586 @@ -870,6 +901,7 @@ name: macrophage def: "A mononuclear phagocyte present in variety of tissues, typically differentiated from monocytes, capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells." [GO_REF:0000031, GOC:add, GOC:tfm, PMID:16213494, PMID:1919437] comment: Morphology: Diameter 30_M-80 _M, abundant cytoplasm, low N/C ratio, eccentric nucleus. Irregular shape with pseudopods, highly adhesive. Contain vacuoles and phagosomes, may contain azurophilic granules; markers: Mouse & Human: CD68, in most cases CD11b. Mouse: in most cases F4/80+; role or process: immune, antigen presentation, & tissue remodelling; lineage: hematopoietic, myeloid. subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "histiocyte" EXACT [] @@ -894,6 +926,7 @@ id: CL:0000236 name: B cell def: "A lymphocyte of B lineage that is capable of B cell mediated immunity." [GO_REF:0000031, GOC:add, GOC:tfm, ISBN:0781735149] subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "B lymphocyte" EXACT [] @@ -913,6 +946,7 @@ relationship: present_in_taxon NCBITaxon:9606 [Term] id: CL:0000255 name: eukaryotic cell +subset: cellxgene_subset xref: MESH:D005057 is_a: CL:0000000 ! cell intersection_of: CL:0000000 ! cell @@ -998,6 +1032,7 @@ is_a: CL:0000211 ! electrically active cell id: CL:0000451 name: dendritic cell def: "A cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation. These cells are lineage negative (CD3-negative, CD19-negative, CD34-negative, and CD56-negative)." [GOC:add, ISBN:0781735149] +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "interdigitating cell" RELATED [] @@ -1042,6 +1077,7 @@ is_a: CL:0000000 ! cell id: CL:0000499 name: stromal cell def: "A connective tissue cell of an organ found in the loose connective tissue. These are most often associated with the uterine mucosa and the ovary as well as the hematopoietic system and elsewhere." [GOC:tfm, MESH:D017154] +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas xref: BTO:0002064 @@ -1054,27 +1090,29 @@ relationship: present_in_taxon NCBITaxon:9606 id: CL:0000513 name: cardiac muscle myoblast def: "A precursor cell destined to differentiate into cardiac muscle cell." [GOC:tfm, MESH:D032386] +subset: cellxgene_subset synonym: "cardiac muscle progenitor cell" EXACT [] synonym: "cardiomyocyte progenitor cell" EXACT [] xref: FMA:84797 is_a: CL:0002494 ! cardiocyte is_a: CL:0010021 ! cardiac myoblast intersection_of: CL:0000056 ! myoblast +intersection_of: develops_into CL:0000746 ! cardiac muscle cell intersection_of: part_of UBERON:0001133 ! cardiac muscle tissue -intersection_of: RO:0002203 CL:0000746 ! develops into cardiac muscle cell relationship: part_of UBERON:0001133 ! cardiac muscle tissue [Term] id: CL:0000514 name: smooth muscle myoblast def: "A precursor cell destined to differentiate into smooth muscle myocytes." [GOC:tfm, MESH:D032390] +subset: cellxgene_subset synonym: "myoblast, smooth muscle" EXACT [MESH:D032390] synonym: "satellite cell" RELATED [] xref: FMA:84798 is_a: CL:0000056 ! myoblast intersection_of: CL:0000056 ! myoblast -intersection_of: RO:0002203 CL:0000192 ! develops into smooth muscle cell -relationship: RO:0002203 CL:0000192 ! develops into smooth muscle cell +intersection_of: develops_into CL:0000192 ! smooth muscle cell +relationship: develops_into CL:0000192 ! smooth muscle cell [Term] id: CL:0000515 @@ -1085,9 +1123,9 @@ xref: FMA:84799 is_a: CL:0000056 ! myoblast is_a: CL:0011026 ! progenitor cell intersection_of: CL:0000056 ! myoblast -intersection_of: RO:0002203 CL:0008002 ! develops into skeletal muscle fiber +intersection_of: develops_into CL:0008002 ! skeletal muscle fiber relationship: develops_from CL:0000355 ! multi-potent skeletal muscle stem cell -relationship: RO:0002203 CL:0008002 ! develops into skeletal muscle fiber +relationship: develops_into CL:0008002 ! skeletal muscle fiber [Term] id: CL:0000518 @@ -1119,6 +1157,7 @@ id: CL:0000540 name: neuron def: "The basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system." [http://en.wikipedia.org/wiki/Neuron, MESH:D009474] comment: These cells are also reportedly CD4-negative and CD200-positive. They are also capable of producing CD40L and IFN-gamma. +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "nerve cell" EXACT [] @@ -1151,6 +1190,7 @@ id: CL:0000542 name: lymphocyte def: "A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin." [GOC:add, ISBN:0683073696, ISBN:0781735149] comment: Editors note: consider adding taxon constraint to vertebrata (PMID:18025161) +subset: cellxgene_subset subset: human_reference_atlas xref: BTO:0000775 xref: CALOHA:TS-0583 @@ -1161,13 +1201,13 @@ is_a: CL:0000842 ! mononuclear cell is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000738 ! leukocyte intersection_of: bearer_of PATO:0001407 ! mononucleate +intersection_of: bearer_of PATO:0040072 ! high nuclear/cytoplasmic ratio intersection_of: has_part CL:0017500 ! neutrophillic cytoplasm -intersection_of: has_part CL:0017505 ! increased nucleus size intersection_of: has_part GO:0000792 ! heterochromatin disjoint_from: CL:0000766 ! myeloid leukocyte +relationship: bearer_of PATO:0040072 ! high nuclear/cytoplasmic ratio relationship: develops_from CL:0000051 ! common lymphoid progenitor relationship: has_part CL:0017500 ! neutrophillic cytoplasm -relationship: has_part CL:0017505 ! increased nucleus size relationship: has_part GO:0000792 ! heterochromatin relationship: present_in_taxon NCBITaxon:9606 @@ -1176,6 +1216,7 @@ id: CL:0000557 name: granulocyte monocyte progenitor cell def: "A hematopoietic progenitor cell that is committed to the granulocyte and monocyte lineages. These cells are CD123-positive, and do not express Gata1 or Gata2 but do express C/EBPa, and Pu.1." [GO_REF:0000031, GOC:amm, GOC:dsd, GOC:tfm, http://en.wikipedia.org/wiki/CFU-GM, http://www.copewithcytokines.de, ISBN:0721601464, MESH:D055014, PMCID:PMC2213186, PMCID:PMC548021, PMID:16551251, PMID:16647566] comment: Originally described in the dendritic cell ontology (DC_CL:0000042)(PMID:19243617). GMPs are reportedly CD16-positive, CD32-positive, CD34-positive, CD38-positive, CD45RA-positive, CD110-negative, CD117-positive, CD123-positive, and SCA1-negative. +subset: cellxgene_subset subset: human_reference_atlas synonym: "CFU-C , Colony forming unit in culture" BROAD [http://www.copewithcytokines.de] synonym: "CFU-GM" RELATED OMO:0003000 [ISBN:0721601464, PMCID:PMC2213186, PMCID:PMC548021] @@ -1212,6 +1253,7 @@ id: CL:0000559 name: promonocyte def: "A precursor in the monocytic series, being a cell intermediate in development between the monoblast and monocyte. This cell is CD11b-positive and has fine azurophil granules." [GOC:tfm, ISBN:0721601464] comment: Morphology: Mononuclear cell, diameter 14-18 _M, fine azurophilic granules; markers: CD11b (shared with many other myeloid cells); location: Adult: bone marrow; Fetal: Liver, Yolk Sac; role or process: hematopoiesis, monocyte development; lineage: hematopoietic, myeloid. +subset: cellxgene_subset subset: human_reference_atlas xref: BTO:0004657 xref: FMA:83551 @@ -1252,6 +1294,7 @@ name: monocyte def: "Myeloid mononuclear recirculating leukocyte that can act as a precursor of tissue macrophages, osteoclasts and some populations of tissue dendritic cells." [GO_REF:0000031, MESH:D009000] comment: Morphology: Mononuclear cell, diameter, 14 to 20 _M, N/C ratio 2:1-1:1. Nucleus may appear in variety of shapes: round, kidney, lobulated, or convoluted. Fine azurophilic granules present; markers: CD11b (shared with other myeloid cells), human: CD14, mouse: F4/80-mid,GR1-low; location: Blood, but can be recruited into tissues; role or process: immune & tissue remodelling; lineage: hematopoietic, myeloid. subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas xref: BTO:0000876 @@ -1275,6 +1318,7 @@ relationship: present_in_taxon NCBITaxon:9606 id: CL:0000623 name: natural killer cell def: "A lymphocyte that can spontaneously kill a variety of target cells without prior antigenic activation via germline encoded activation receptors and also regulate immune responses via cytokine release and direct contact with other cells." [GOC:add, ISBN:0781735149, PMID:15771571] +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "large granular lymphocyte" BROAD [] @@ -1306,11 +1350,12 @@ relationship: present_in_taxon NCBITaxon:9606 id: CL:0000680 name: muscle precursor cell def: "A non-terminally differentiated cell that is capable of developing into a muscle cell." [GOC:add] +subset: cellxgene_subset is_a: CL:0000055 ! non-terminally differentiated cell intersection_of: CL:0011115 ! precursor cell -intersection_of: RO:0002203 CL:0000187 ! develops into muscle cell +intersection_of: develops_into CL:0000187 ! muscle cell relationship: develops_from CL:0000222 ! mesodermal cell -relationship: RO:0002203 CL:0000187 ! develops into muscle cell +relationship: develops_into CL:0000187 ! muscle cell [Term] id: CL:0000723 @@ -1342,6 +1387,7 @@ relationship: has_part GO:0030017 ! sarcomere id: CL:0000738 name: leukocyte def: "An achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue." [GOC:add, GOC:tfm, ISBN:978-0-323-05290-0] +subset: cellxgene_subset subset: human_reference_atlas synonym: "immune cell" RELATED [] synonym: "leucocyte" EXACT [] @@ -1370,6 +1416,7 @@ name: cardiac muscle cell alt_id: FMA:83808 def: "Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. In mammals, the contractile fiber resembles those of skeletal muscle but are only one third as large in diameter, are richer in sarcoplasm, and contain centrally located instead of peripheral nuclei." [GOC:mtg_cardiacconduct_nov11, GOC:tfm, ISBN:0323052908, PMID:22426062, PMID:4711263] comment: This class encompasses the muscle cells responsible for heart* contraction in both vertebrates and arthropods. The ultrastucture of a wide range of arthropod heart cells has been examined including spiders, horseshoe crabs, crustaceans (see Sherman, 1973 and refs therein) and insects (see Lehmacher et al (2012) and refs therein). According to these refs, the cells participating in heart contraction in all cases are transversely striated. Insects hearts additionally contain ostial cells, also transversely striated muscle cells, but which do not participate in heart contraction. +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "cardiac muscle fiber" EXACT [GO:0048739] @@ -1397,6 +1444,7 @@ relationship: present_in_taxon NCBITaxon:9606 id: CL:0000763 name: myeloid cell def: "A cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage." [GOC:add] +subset: cellxgene_subset xref: BTO:0001441 xref: CALOHA:TS-0647 xref: MESH:D022423 @@ -1409,6 +1457,7 @@ relationship: develops_from CL:0000049 ! common myeloid progenitor id: CL:0000766 name: myeloid leukocyte def: "A cell of the monocyte, granulocyte, or mast cell lineage." [GOC:add] +subset: cellxgene_subset is_a: CL:0000738 {is_inferred="true"} ! leukocyte is_a: CL:0000763 ! myeloid cell intersection_of: CL:0000738 ! leukocyte @@ -1419,6 +1468,7 @@ id: CL:0000775 name: neutrophil def: "Any of the immature or mature forms of a granular leukocyte that in its mature form has a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes." [GOC:add, GOC:amm, GOC:tfm, ISBN:0721601464] subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "neutrocyte" EXACT [] synonym: "neutrophil leucocyte" EXACT [] @@ -1449,6 +1499,7 @@ id: CL:0000782 name: myeloid dendritic cell def: "A dendritic cell of the myeloid lineage." [GOC:add, PMID:10449155, PMID:17332250, PMID:9521319] comment: These cells are CD1a-negative, CD1b-positive, CD11a-positive, CD11c-positive, CD13-positive, CD14-negative, CD20-negative, CD21-negative, CD33-positive, CD40-negative, CD50-positive, CD54-positive, CD58-positive, CD68-negative, CD80-negative, CD83-negative, CD85j-positive, CD86-positive, CD89-negative, CD95-positive, CD120a-negative, CD120b-positive, CD123-negative, CD178-negative, CD206-negative, CD207-negative, CD209-negative, and TNF-alpha-negative. Upon TLR stimulation, they are capable of producing high levels of TNF-alpha, IL-6, CXCL8 (IL-8). +subset: cellxgene_subset synonym: "CD11c+CD123- DC" EXACT [] synonym: "interdigitating cell" BROAD [] synonym: "mDC" EXACT [] @@ -1494,6 +1545,7 @@ id: CL:0000826 name: pro-B cell def: "A progenitor cell of the B cell lineage, with some lineage specific activity such as early stages of recombination of B cell receptor genes, but not yet fully committed to the B cell lineage until the expression of PAX5 occurs." [GOC:add, GOC:dsd, ISBN:0781735149, PMID:12633665, PMID:16551251, PMID:18432934] comment: Human pro-B cells are reportedly CD10-positive, CD22-positive, CD34-positive, CD38-positive, CD45-low, CD48-positive, CD79a-positive, CD127-positive, CD184-positive, RAG-positive, TdT-positive, Vpre-B-positive, pre-BCR-negative, IgD-negative, and IgM-negative. Transcription factors expressed: Pax5-positive, EBF-positive, E2A-negative, Ikaros-negative, and PU.1-negative. +subset: cellxgene_subset subset: human_reference_atlas synonym: "pre-B cell (Philadelphia nomenclature)" RELATED [PMID:11244048] synonym: "pre-pro B cell" BROAD [PMID:17582343] @@ -1521,6 +1573,7 @@ relationship: present_in_taxon NCBITaxon:9606 id: CL:0000827 name: pro-T cell def: "A lymphoid progenitor cell of the T cell lineage, with some lineage specific marker expression, but not yet fully committed to the T cell lineage." [GOC:add, ISBN:0781735149] +subset: cellxgene_subset synonym: "DN1 cell" NARROW [] synonym: "DN1 thymocyte" NARROW [] synonym: "pro-T lymphocyte" EXACT [] @@ -1538,6 +1591,7 @@ name: hematopoietic multipotent progenitor cell def: "A hematopoietic multipotent progenitor cell is multipotent, but not capable of long-term self-renewal. These cells are characterized as lacking lineage cell surface markers and being CD34-positive in both mice and humans." [GOC:add, GOC:tfm, PMID:19022770] comment: Markers differ between mouse and human. subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "hemopoietic progenitor cell" EXACT [] synonym: "MPP" EXACT [] @@ -1585,6 +1639,7 @@ id: CL:0000838 name: lymphoid lineage restricted progenitor cell def: "A progenitor cell restricted to the lymphoid lineage." [GOC:add, GOC:tfm] comment: Note that this is a class of cell types, not an identified single cell type. +subset: cellxgene_subset synonym: "lymphoid progenitor cell" BROAD [] xref: BTO:0004731 xref: CALOHA:TS-2025 @@ -1601,6 +1656,7 @@ id: CL:0000839 name: myeloid lineage restricted progenitor cell def: "A progenitor cell restricted to the myeloid lineage." [GOC:add, GOC:tfm, PMID:19022770] comment: Note that this is a class of cell types, not an identified single cell type. +subset: cellxgene_subset subset: human_reference_atlas synonym: "myeloid progenitor cell" BROAD [] xref: BTO:0004730 @@ -1618,6 +1674,7 @@ id: CL:0000842 name: mononuclear cell def: "A leukocyte with a single non-segmented nucleus in the mature form." [GOC:add] subset: blood_and_immune_upper_slim +subset: cellxgene_subset synonym: "mononuclear leukocyte" EXACT [] synonym: "peripheral blood mononuclear cell" NARROW [] xref: BTO:0000878 @@ -1642,6 +1699,7 @@ relationship: present_in_taxon NCBITaxon:9606 id: CL:0000988 name: hematopoietic cell def: "A cell of a hematopoietic lineage." [GO_REF:0000031, GOC:add] +subset: cellxgene_subset synonym: "haematopoietic cell" EXACT [] synonym: "haemopoietic cell" EXACT [] synonym: "hemopoietic cell" EXACT [] @@ -1657,6 +1715,7 @@ name: conventional dendritic cell def: "Conventional dendritic cell is a dendritic cell that is CD11c-high." [GO_REF:0000031, GOC:amm, PMID:17850486] comment: Originally described in the dendritic cell ontology (DC_CL:0000003)(PMID:19243617) These cells are also CD20-negative, MHCII-positive. subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "cDC" EXACT [] synonym: "DC1" EXACT [] @@ -1730,6 +1789,7 @@ id: CL:0001065 name: innate lymphoid cell def: "A lymphocyte that lacks characteristic T cell, B cell, myeloid cell, and dendritic cell markers, that functions as part of the innate immune response to produce cytokines and other effector responses." [GOC:add, GOC:dsd, PMID:23292121, PMID:23348417] subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas is_a: CL:0000542 ! lymphocyte intersection_of: CL:0000542 ! lymphocyte @@ -1762,6 +1822,7 @@ property_value: dcterms-date "2017-01-30T20:42:44Z" xsd:dateTime id: CL:0002009 name: macrophage dendritic cell progenitor def: "A progenitor cell that can give rise to plasmacytoid and myeloid dendritic cells, and to monocytes and macrophages." [GOC:tfm, PMID:19273628] +subset: cellxgene_subset synonym: "MDP" EXACT [] is_a: CL:0000763 ! myeloid cell is_a: CL:0002032 {is_inferred="true"} ! hematopoietic oligopotent progenitor cell @@ -1820,6 +1881,7 @@ id: CL:0002092 name: bone marrow cell def: "A cell found in the bone marrow. This can include fibroblasts, macrophages, adipocytes, osteoblasts, osteoclasts, endothelial cells and hematopoietic cells." [GOC:tfm, ISBN:0618947256] comment: MH consider whether bone marrow cells are bone cells in the structural sense vs. being part of bone organ sense. +subset: cellxgene_subset xref: BTO:0004850 xref: FMA:83621 xref: MESH:D001854 @@ -1858,6 +1920,7 @@ creation_date: 2010-09-07T03:32:33Z id: CL:0002319 name: neural cell def: "A cell that is part of the nervous system." [GOC:tfm, ISBN:0618947256] +subset: cellxgene_subset xref: CALOHA:TS-2040 xref: FMA:70333 is_a: CL:0000000 ! cell @@ -1871,6 +1934,7 @@ creation_date: 2010-09-15T01:34:57Z id: CL:0002320 name: connective tissue cell def: "A cell of the supporting or framework tissue of the body, arising chiefly from the embryonic mesoderm and including adipose tissue, cartilage, and bone." [GOC:tfm, ISBN:0618947256] +subset: cellxgene_subset xref: CALOHA:TS-2096 xref: FMA:63875 xref: MESH:D003239 @@ -1956,12 +2020,14 @@ is_a: CL:0000187 ! muscle cell id: CL:0008001 name: hematopoietic precursor cell def: "Any hematopoietic cell that is a precursor of some other hematopoietic cell type." [GOC:dos] +subset: cellxgene_subset is_a: CL:0000988 ! hematopoietic cell [Term] id: CL:0008002 name: skeletal muscle fiber def: "A transversely striated, synctial cell of skeletal muscle. It is formed when proliferating myoblasts exit the cell cycle, differentiate and fuse." [GOC:tfm, ISBN:0323052908] +subset: cellxgene_subset xref: MESH:D018485 is_a: CL:0000188 ! cell of skeletal muscle is_a: CL:0002372 ! myotube @@ -1986,6 +2052,7 @@ relationship: part_of UBERON:8600004 ! visceral muscle tissue id: CL:0008019 name: mesenchymal cell def: "A non-polarised cell precursor cell that is part of some mesenchyme, is associated with the cell matrix but is not connected to other cells and is capable of migration." [] +subset: cellxgene_subset subset: human_reference_atlas synonym: "mesenchyme cell" EXACT [] is_a: CL:0000219 ! motile cell @@ -2018,13 +2085,14 @@ name: cardiac myoblast xref: MESH:D032386 is_a: CL:0000056 ! myoblast intersection_of: CL:0000056 ! myoblast -intersection_of: RO:0002203 CL:0000746 ! develops into cardiac muscle cell -relationship: RO:0002203 CL:0000746 ! develops into cardiac muscle cell +intersection_of: develops_into CL:0000746 ! cardiac muscle cell +relationship: develops_into CL:0000746 ! cardiac muscle cell [Term] id: CL:0011012 name: neural crest cell def: "A cell of the neural crest. Neural crest cells are multipotent. Premigratory neural crest cells are found at the neural plate boarder, some of which will undergo ectomesynchymal transition and delamination to form migratory neural crest cells." [https://orcid.org/0000-0001-5208-3432, https://orcid.org/0000-0002-9900-7880] +subset: cellxgene_subset is_a: CL:0000048 ! multi fate stem cell is_a: CL:0002321 ! embryonic cell (metazoa) @@ -2032,6 +2100,7 @@ is_a: CL:0002321 ! embryonic cell (metazoa) id: CL:0011026 name: progenitor cell def: "A precursor cell that has a tendency to differentiate into a specific type of cell. They are descendants of stem cells, only they are more constrained in their differentiation potential or capacity for self-renewal, and are often more limited in both senses." [https://doi.org/10.1016/B978-0-12-409503-8.00002-0, ISBN:978-1-62808-994-3] +subset: cellxgene_subset is_a: CL:0011115 ! precursor cell intersection_of: CL:0011115 ! precursor cell intersection_of: develops_from CL:0000034 ! stem cell @@ -2043,6 +2112,7 @@ id: CL:0011115 name: precursor cell def: "A cell that, by division or terminal differentiation, can give rise to other cell types." [GOC:dos] comment: Work is needed on GO 'cell differentiation' before it is clear whether the equivalent class definition 'native cell' that capable_of some 'cell differentiation' works. Also, may want to consider merging this with non-terminally differentiated cell. +subset: cellxgene_subset is_a: CL:0000000 ! cell intersection_of: CL:0000000 ! cell intersection_of: capable_of GO:0030154 ! cell differentiation @@ -2070,17 +2140,6 @@ relationship: bearer_of PATO:0002094 ! basophilic relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2009-12-22T04:24:54Z -[Term] -id: CL:0017505 -name: increased nucleus size -def: "A nucleus size quality which is relatively high compared to the amount of cytoplasm present in the same cell." [GOC:tfm] -is_a: GO:0005634 ! nucleus -intersection_of: GO:0005634 ! nucleus -intersection_of: bearer_of PATO:0000586 ! increased size -relationship: bearer_of PATO:0000586 ! increased size -relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 -creation_date: 2009-12-23T10:53:24Z - [Term] id: CL:1001610 name: bone marrow hematopoietic cell @@ -2596,7 +2655,7 @@ id: GO:0005575 name: cellular_component namespace: cellular_component alt_id: GO:0008372 -def: "A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex)." [GOC:pdt] +def: "A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex)." [GOC:pdt] comment: Note that, in addition to forming the root of the cellular component ontology, this term is recommended for the annotation of gene products whose cellular component is unknown. When this term is used for annotation, it indicates that no information was available about the cellular component of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this. subset: goslim_candida subset: goslim_chembl @@ -2627,8 +2686,8 @@ subset: goslim_metagenomics subset: goslim_mouse subset: goslim_pir subset: goslim_plant +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset synonym: "extracellular" EXACT [] xref: Wikipedia:Extracellular is_a: GO:0110165 ! cellular anatomical entity @@ -2724,8 +2783,8 @@ subset: goslim_flybase_ribbon subset: goslim_generic subset: goslim_metagenomics subset: goslim_pir +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset synonym: "chromatid" RELATED [] synonym: "interphase chromosome" NARROW [] synonym: "prophase chromosome" NARROW [] @@ -2759,8 +2818,8 @@ subset: goslim_chembl subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset xref: Wikipedia:Cytoplasm is_a: GO:0110165 ! cellular anatomical entity relationship: part_of GO:0005622 ! intracellular anatomical structure @@ -2822,8 +2881,8 @@ subset: goslim_generic subset: goslim_metagenomics subset: goslim_mouse subset: goslim_plant +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset synonym: "bacterial inner membrane" NARROW [] synonym: "cell membrane" EXACT [] synonym: "cellular membrane" EXACT [NIF_Subcellular:sao6433132645] @@ -2876,8 +2935,8 @@ def: "Any process in which a new genotype is formed by reassortment of genes res subset: goslim_drosophila subset: goslim_generic subset: goslim_pombe +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset is_a: GO:0006259 ! DNA metabolic process [Term] @@ -2895,7 +2954,7 @@ subset: goslim_chembl subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "single-organism transport" RELATED [] is_a: GO:0051234 ! establishment of localization property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20292" xsd:anyURI @@ -3744,8 +3803,8 @@ subset: goslim_flybase_ribbon subset: goslim_generic subset: goslim_mouse subset: goslim_pombe +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset synonym: "biological signaling" EXACT [] synonym: "signaling process" EXACT [] synonym: "signalling" EXACT [] @@ -3792,7 +3851,7 @@ id: GO:0030030 name: cell projection organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon." [GOC:jl, GOC:mah, http://www.cogsci.princeton.edu/~wn/] -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "cell projection organisation" EXACT [] synonym: "cell projection organization and biogenesis" RELATED [GOC:mah] synonym: "cell surface structure organization and biogenesis" RELATED [GOC:mah] @@ -3989,7 +4048,7 @@ subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_pir -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "matrisome" NARROW [] synonym: "proteinaceous extracellular matrix" EXACT [] xref: NIF_Subcellular:nlx_subcell_20090513 @@ -4358,7 +4417,7 @@ subset: goslim_agr subset: goslim_flybase_ribbon subset: goslim_mouse subset: goslim_pir -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "cell process" BROAD [] synonym: "cellular process" BROAD [] synonym: "cellular projection" EXACT [] @@ -4395,12 +4454,14 @@ alt_id: GO:0034960 alt_id: GO:0043283 alt_id: GO:0044259 def: "The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:mah] +subset: gocheck_do_not_annotate subset: goslim_pir synonym: "biopolymer metabolic process" EXACT [GOC:mtg_chebi_dec09] synonym: "macromolecule metabolism" EXACT [] synonym: "multicellular organismal macromolecule metabolic process" NARROW [] synonym: "organismal macromolecule metabolism" EXACT [] is_a: GO:0008152 ! metabolic process +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI [Term] id: GO:0043207 @@ -4418,7 +4479,7 @@ def: "Organized structure of distinctive morphology and function. Includes the n subset: goslim_chembl subset: goslim_generic subset: goslim_pir -subset: prokaryote_subset +subset: goslim_prokaryote xref: NIF_Subcellular:sao1539965131 xref: Wikipedia:Organelle is_a: GO:0110165 ! cellular anatomical entity @@ -4555,7 +4616,7 @@ synonym: "innate immunity" EXACT [GOC:pg] synonym: "nonspecific immune response" EXACT [] xref: Wikipedia:Innate_immune_system is_a: GO:0006955 ! immune response -is_a: GO:0098542 ! defense response to other organism +is_a: GO:0140546 ! defense response to symbiont [Term] id: GO:0045202 @@ -4814,6 +4875,7 @@ id: GO:0048856 name: anatomical structure development namespace: biological_process def: "The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome." [GO_REF:0000021] +subset: gocheck_do_not_annotate subset: goslim_chembl subset: goslim_generic subset: goslim_plant @@ -4822,6 +4884,7 @@ is_a: GO:0032502 ! developmental process intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of UBERON:0000061 ! anatomical structure relationship: results_in_development_of UBERON:0000061 ! anatomical structure +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI [Term] id: GO:0048869 @@ -4839,7 +4902,7 @@ def: "Any process involved in the controlled self-propelled movement of a cell t subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "cell locomotion" EXACT [] synonym: "cell movement" RELATED [] synonym: "movement of a cell" EXACT [] @@ -4960,7 +5023,7 @@ subset: goslim_agr subset: goslim_flybase_ribbon subset: goslim_mouse subset: goslim_pir -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "physiological response to stimulus" EXACT [] is_a: GO:0008150 ! biological_process @@ -5176,7 +5239,7 @@ subset: goslim_drosophila subset: goslim_generic subset: goslim_pir subset: goslim_pombe -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "cellular membrane organisation" EXACT [] synonym: "cellular membrane organization" EXACT [] synonym: "membrane organisation" EXACT [GOC:mah] @@ -5263,10 +5326,12 @@ id: GO:0071704 name: organic substance metabolic process namespace: biological_process def: "The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon." [GOC:mah] +subset: gocheck_do_not_annotate synonym: "organic molecular entity metabolic process" EXACT [] synonym: "organic molecular entity metabolism" EXACT [] synonym: "organic substance metabolism" EXACT [] is_a: GO:0008152 ! metabolic process +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI created_by: mah creation_date: 2010-03-08T03:32:18Z @@ -5289,7 +5354,7 @@ creation_date: 2010-09-10T01:39:16Z id: GO:0071944 name: cell periphery namespace: cellular_component -def: "The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures." [GOC:pdt] +def: "The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures." [GOC:pdt] subset: goslim_flybase_ribbon is_a: GO:0110165 ! cellular anatomical entity created_by: mah @@ -5366,7 +5431,7 @@ namespace: biological_process alt_id: GO:0009814 def: "Reactions triggered in response to the presence of another organism that act to protect the cell or organism from damage caused by that organism." [GOC:dos] subset: goslim_generic -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "defence response incompatible interaction" NARROW [] synonym: "defence response to pathogen, incompatible interaction" NARROW [] synonym: "defense response, incompatible interaction" NARROW [] @@ -5589,6 +5654,7 @@ subset: goslim_pir is_a: GO:0005575 ! cellular_component is_a: UBERON:0000061 ! anatomical structure property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24200" xsd:anyURI +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI created_by: kmv creation_date: 2019-08-12T18:01:37Z @@ -5647,6 +5713,16 @@ relationship: has_target_start_location GO:0005622 ! intracellular anatomical st created_by: pg creation_date: 2019-05-22T11:20:45Z +[Term] +id: GO:0140546 +name: defense response to symbiont +namespace: biological_process +def: "Reactions triggered in response to the presence of a symbiont that act to protect or prevent damage to the host." [GOC:pg] +is_a: GO:0098542 ! defense response to other organism +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20261" xsd:anyURI +created_by: pg +creation_date: 2020-11-11T17:19:06Z + [Term] id: GO:1901576 name: organic substance biosynthetic process @@ -6070,30 +6146,6 @@ subset: attribute_slim synonym: "relational shape quality" EXACT [] is_a: PATO:0000051 ! morphology -[Term] -id: PATO:0000068 -name: qualitative -namespace: quality -comment: TODO: define this or obsolete it and move children somewhere else. -is_a: PATO:0000001 ! quality - -[Term] -id: PATO:0000069 -name: deviation (from_normal) -namespace: quality -def: "A quality inhering in a bearer by virtue of the whether the bearer differs from normal or average." [PATOC:GVG] -subset: attribute_slim -is_a: PATO:0000068 ! qualitative - -[Term] -id: PATO:0000117 -name: size -namespace: quality -def: "A morphology quality inhering in a bearer by virtue of the bearer's physical magnitude." [WordNet:WordNet] -subset: attribute_slim -subset: scalar_slim -is_a: PATO:0000051 ! morphology - [Term] id: PATO:0000141 name: structure @@ -6117,36 +6169,6 @@ synonym: "round" RELATED [] synonym: "rounded" RELATED [] is_a: PATO:0000947 ! elliptic -[Term] -id: PATO:0000461 -name: normal -namespace: quality -def: "A quality inhering in a bearer by virtue of the bearer's exhibiting no deviation from normal or average." [PATOC:GVG] -subset: abnormal_slim -subset: mpath_slim -subset: value_slim -synonym: "average" RELATED [] -is_a: PATO:0000068 ! qualitative -property_value: RO:0002604 PATO:0000460 - -[Term] -id: PATO:0000586 -name: increased size -namespace: quality -alt_id: PATO:0001202 -def: "A size quality which is relatively high." [PATOC:GVG] -subset: value_slim -synonym: "big" RELATED [] -synonym: "enlarged" RELATED [] -synonym: "expanded" RELATED [] -synonym: "great" RELATED [] -synonym: "large" RELATED [] -is_a: PATO:0000117 ! size -is_a: PATO:0002305 ! increased object quality -intersection_of: PATO:0000117 ! size -intersection_of: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal -property_value: RO:0002604 PATO:0000587 - [Term] id: PATO:0000947 name: elliptic @@ -6430,32 +6452,6 @@ is_a: PATO:0002078 ! hollow relationship: dc-contributor https://orcid.org/0000-0002-2061-091X creation_date: 2011-06-08T06:33:50Z -[Term] -id: PATO:0002300 -name: increased quality -namespace: quality -def: "A quality that has a value that is increased compared to normal or average." [PATOC:GVG] -is_a: PATO:0000069 ! deviation (from_normal) -intersection_of: PATO:0000001 ! quality -intersection_of: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal -relationship: dc-contributor https://orcid.org/0000-0002-2061-091X -relationship: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal -property_value: RO:0002604 PATO:0002301 -creation_date: 2011-06-16T06:39:43Z - -[Term] -id: PATO:0002305 -name: increased object quality -namespace: quality -def: "A quality of an object that has a value that is increased compared to normal or average." [PATOC:GVG] -is_a: PATO:0001241 ! physical object quality -is_a: PATO:0002300 ! increased quality -intersection_of: PATO:0001241 ! physical object quality -intersection_of: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal -relationship: dc-contributor https://orcid.org/0000-0002-2061-091X -property_value: RO:0002604 PATO:0002303 -creation_date: 2011-06-16T06:54:01Z - [Term] id: PATO:0002309 name: fiber shaped @@ -6518,6 +6514,16 @@ comment: A complete coverage of this domain would subclasses homopolymeric, copo subset: value_slim is_a: PATO:0000141 ! structure +[Term] +id: PATO:0040072 +name: high nuclear/cytoplasmic ratio +namespace: quality +def: "A quality inhering in a cell by virtue of the cell having a high nuclear/cytoplasmic ratio." [http://lymerick.net/blood-cells.pdf, Wikipedia:NC_ratio&oldid=931936284] +comment: A high nuclear/cytolasmic ratio is 70% or higher. +synonym: "high N:C ratio" EXACT [] +is_a: PATO:0001396 ! cellular quality +created_by: http://orcid.org/0000-0001-5208-3432 + [Term] id: PATO:0070044 name: anatomical structure quality @@ -7405,7 +7411,7 @@ xref: CALOHA:TS-2043 xref: EHDAA2:0001824 xref: EHDAA:500 xref: EMAPA:35955 -xref: FBbt:00005155 +xref: FBbt:00005155 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: GAID:63 xref: HAO:0000930 xref: MA:0000017 @@ -7446,7 +7452,7 @@ def: "Dense regular connective tissue that connects muscle to bone[VSAO]." [GO_R subset: pheno_slim subset: uberon_slim synonym: "sinew" RELATED [Wikipedia:Tendon] -synonym: "tendo" RELATED LATIN [Wikipedia:Tendon] +synonym: "tendo" RELATED OMO:0003011 [Wikipedia:Tendon] xref: AEO:0000091 xref: BTO:0001356 xref: CALOHA:TS-1021 @@ -7488,7 +7494,7 @@ synonym: "ducts" RELATED OMO:0003004 [XAO:0004000] synonym: "exocrine duct" NARROW [] synonym: "exocrine gland duct" NARROW [] xref: AAO:0011123 -xref: FBbt:00100314 +xref: FBbt:00100314 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:30320 xref: galen:Duct xref: NCIT:C12948 @@ -7539,7 +7545,7 @@ xref: BILA:0000003 xref: CARO:0000003 xref: EHDAA2:0003003 xref: EMAPA:0 -xref: FBbt:00007001 +xref: FBbt:00007001 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:305751 xref: FMA:67135 xref: GAID:781 @@ -7809,13 +7815,13 @@ synonym: "fertilized egg stage" RELATED [] synonym: "one cell stage" EXACT [] synonym: "one-cell stage" RELATED [VHOG:0000745] synonym: "zygote" RELATED [VHOG:0000745] -synonym: "zygotum" RELATED LATIN [Wikipedia:Zygote] +synonym: "zygotum" RELATED OMO:0003011 [Wikipedia:Zygote] xref: BilaDO:0000005 xref: BILS:0000106 xref: EFO:0001322 xref: EHDAA:27 xref: FBdv:00005288 -xref: IDOMAL:0000302 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: IDOMAL:0000302 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: NCIT:C12601 xref: PdumDv:0000100 xref: VHOG:0000745 @@ -7963,13 +7969,13 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "adult mouth" NARROW [] -synonym: "cavital oralis" RELATED LATIN [Wikipedia:Mouth] +synonym: "cavital oralis" RELATED OMO:0003011 [Wikipedia:Mouth] synonym: "cavitas oris" RELATED [BTO:0001090] synonym: "cavum oris" RELATED [BTO:0001090] synonym: "mouth cavity" RELATED [BTO:0001090] synonym: "oral region" RELATED [EHDAA2:0001326] synonym: "oral vestibule" RELATED [BTO:0001090] -synonym: "regio oralis" EXACT LATIN [BTO:0004698, FMA:49184, FMA:TA] +synonym: "regio oralis" EXACT OMO:0003011 [BTO:0004698, FMA:49184, FMA:TA] synonym: "rima oris" RELATED [BTO:0001090] synonym: "stoma" RELATED [] synonym: "stomatodaeum" RELATED [VHOG:0000812] @@ -7984,7 +7990,7 @@ xref: EFO:0000825 xref: EHDAA2:0001326 xref: EHDAA:542 xref: EMAPA:16262 -xref: FBbt:00003126 +xref: FBbt:00003126 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:49184 xref: GAID:75 xref: galen:Mouth @@ -8102,7 +8108,7 @@ xref: CALOHA:TS-2101 xref: CARO:0000004 xref: EHDAA2:0003004 xref: EMAPA:35178 -xref: FBbt:00007019 +xref: FBbt:00007019 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:9669 xref: galen:BodySubstance xref: HAO:0000004 @@ -8137,7 +8143,7 @@ xref: AEO:0000005 xref: BILA:0000005 xref: CARO:0000005 xref: EHDAA2:0003005 -xref: FBbt:00007017 +xref: FBbt:00007017 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:5897 xref: HAO:0000005 xref: NCIT:C94478 @@ -8165,7 +8171,7 @@ xref: AEO:0000006 xref: BILA:0000006 xref: CARO:0000006 xref: EHDAA2:0003006 -xref: FBbt:00007016 +xref: FBbt:00007016 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:67165 xref: HAO:0000006 xref: TAO:0001836 @@ -8191,7 +8197,7 @@ xref: AEO:0000007 xref: BILA:0000007 xref: CARO:0000007 xref: EHDAA2:0003007 -xref: FBbt:00007015 +xref: FBbt:00007015 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:67112 xref: HAO:0000007 xref: TAO:0001835 @@ -8229,11 +8235,11 @@ xref: EHDAA2:0003011 xref: EHDAA:392 xref: EMAPA:16103 xref: EV:0100000 -xref: FBbt:00004856 +xref: FBbt:00004856 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:7149 xref: galen:AnatomicalSystem xref: HAO:0000011 -xref: IDOMAL:0002460 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: IDOMAL:0002460 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: MA:0000003 xref: NCIT:C12919 xref: SCTID:278195005 @@ -8284,7 +8290,7 @@ xref: EHDAA2:0003191 xref: EHDAA:1 xref: EMAPA:25765 xref: EV:0100016 -xref: FBbt:00000001 +xref: FBbt:00000001 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:256135 xref: galen:Organism xref: HAO:0000012 @@ -8329,7 +8335,7 @@ xref: CARO:0000032 xref: EFO:0000808 xref: EHDAA2:0003032 xref: EMAPA:36031 -xref: FBbt:00007009 +xref: FBbt:00007009 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:7153 xref: galen:BodyPart xref: HAO:0000032 @@ -8365,7 +8371,7 @@ xref: AEO:0000040 xref: BILA:0000040 xref: CARO:0000040 xref: EHDAA2:0003040 -xref: FBbt:00007013 +xref: FBbt:00007013 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:63863 xref: HAO:0000040 xref: TAO:0000382 @@ -8385,8 +8391,7 @@ namespace: uberon def: "Anatomical group whose component anatomical structures lie in close proximity to each other." [FBbt:00007277] subset: common_anatomy subset: upper_level -xref: FBbt:00007277 -xref: IDOMAL:0002461 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: FBbt:00007277 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: VHOG:0001737 is_a: UBERON:0034923 ! disconnected anatomical group relationship: present_in_taxon NCBITaxon:33090 @@ -8412,7 +8417,7 @@ xref: CALOHA:TS-2119 xref: CARO:0000042 xref: EHDAA2:0003042 xref: EHDAA:46 -xref: FBbt:00005835 +xref: FBbt:00005835 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:85537 xref: HAO:0000042 xref: NCIT:C34055 @@ -8448,7 +8453,7 @@ xref: CALOHA:TS-2090 xref: CARO:0000043 xref: EHDAA2:0003043 xref: EMAPA:35868 -xref: FBbt:00007003 +xref: FBbt:00007003 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:9637 xref: galen:Tissue xref: HAO:0000043 @@ -8483,7 +8488,7 @@ xref: AEO:0000055 xref: BILA:0000055 xref: CARO:0000055 xref: EHDAA2:0003055 -xref: FBbt:00007010 +xref: FBbt:00007010 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: HAO:0000055 xref: TAO:0001488 xref: TGMA:0001847 @@ -8516,7 +8521,7 @@ xref: CALOHA:TS-0288 xref: CARO:0000066 xref: EHDAA2:0003066 xref: EMAPA:32738 -xref: FBbt:00007005 +xref: FBbt:00007005 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:9639 xref: GAID:402 xref: HAO:0000066 @@ -8620,11 +8625,11 @@ xref: EHDAA2:0000002 xref: EHDAA2_RETIRED:0003236 xref: EHDAA:38 xref: EMAPA:16039 -xref: FBbt:00000052 +xref: FBbt:00000052 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:69068 xref: GAID:963 xref: http://neurolex.org/wiki/Category\:Embryonic_organism -xref: IDOMAL:0000646 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: IDOMAL:0000646 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: MAT:0000226 xref: MESH:D004622 xref: MIAA:0000019 @@ -8664,7 +8669,7 @@ xref: AAO:0000480 xref: BILA:0000035 xref: BTO:0000556 xref: EMAPA:36033 -xref: FBbt:00000110 +xref: FBbt:00000110 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:69069 xref: GAID:1303 xref: MESH:D005855 @@ -8699,7 +8704,7 @@ xref: EFO:0000414 xref: EHDAA2:0000428 xref: EMAPA:16069 xref: EV:0100003 -xref: FBbt:00000111 +xref: FBbt:00000111 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:69070 xref: GAID:1304 xref: MAT:0000155 @@ -8740,7 +8745,7 @@ xref: EFO:0002545 xref: EHDAA2:0000436 xref: EMAPA:16062 xref: EV:0100005 -xref: FBbt:00000125 +xref: FBbt:00000125 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:69071 xref: GAID:1305 xref: MAT:0000175 @@ -8786,7 +8791,7 @@ xref: EHDAA:160 xref: EHDAA:183 xref: EMAPA:16083 xref: EV:0100006 -xref: FBbt:00000126 +xref: FBbt:00000126 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:69072 xref: GAID:522 xref: MAT:0000174 @@ -8830,7 +8835,7 @@ synonym: "stomodeal-hypophyseal primordium" BROAD [XAO:0000269] xref: BTO:0004224 xref: EHDAA2:0001929 xref: EMAPA:16263 -xref: FBbt:00000439 +xref: FBbt:00000439 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:295846 xref: NCIT:C34306 xref: TAO:0001290 @@ -8868,7 +8873,7 @@ xref: EFO:0002969 xref: EHDAA2:0002224 xref: EMAPA:35306 xref: EV:0100128 -xref: FBbt:00005068 +xref: FBbt:00005068 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:9668 xref: GAID:439 xref: MA:0000012 @@ -8916,7 +8921,7 @@ xref: BTO:0000439 xref: CALOHA:TS-0309 xref: EFO:0000827 xref: EV:0100336 -xref: FBbt:00005162 +xref: FBbt:00005162 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: GAID:69 xref: MAT:0000140 xref: MESH:D005123 @@ -8996,7 +9001,7 @@ xref: BTO:0000058 xref: CALOHA:TS-1293 xref: EFO:0000793 xref: EV:0100056 -xref: FBbt:00005055 +xref: FBbt:00005055 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:7152 xref: GAID:278 xref: galen:DigestiveSystem @@ -9037,9 +9042,10 @@ namespace: uberon def: "Organ system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis[WP]." [Wikipedia:Circulatory_system] subset: human_reference_atlas subset: uberon_slim -synonym: "systema cardiovasculare" RELATED LATIN [Wikipedia:Circulatory_system] +synonym: "systema cardiovasculare" RELATED OMO:0003011 [Wikipedia:Circulatory_system] xref: AAO:0000959 xref: CALOHA:TS-2103 +xref: MESH:D002319 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} xref: VHOG:0001248 xref: Wikipedia:Circulatory_system is_a: UBERON:0000467 ! anatomical system @@ -9078,7 +9084,7 @@ synonym: "muscles" RELATED [] synonym: "muscles set" EXACT [] synonym: "musculature" EXACT [] synonym: "musculature system" RELATED [] -synonym: "musculi" EXACT LATIN [FMA:32558, FMA:TA] +synonym: "musculi" EXACT OMO:0003011 [FMA:32558, FMA:TA] synonym: "set of muscles" EXACT [FMA:32558] synonym: "set of skeletal muscles" EXACT [MA:0000165] xref: AAO:0011066 @@ -9109,12 +9115,13 @@ namespace: uberon def: "The nervous system is an organ system containing predominantly neuron and glial cells. In bilaterally symmetrical organism, it is arranged in a network of tree-like structures connected to a central body. The main functions of the nervous system are to regulate and control body functions, and to receive sensory input, process this information, and generate behavior [CUMBO]." [BIRNLEX:844, ISBN:0-14-051288-8, ISBN:3110148986, NLM:nervous+system, WB:rynl, Wikipedia:Nervous_system, ZFIN:curator] subset: cumbo subset: efo_slim +subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "nerve net" NARROW [Wikipedia:Nerve_net] synonym: "neurological system" EXACT [GO:0050877] -synonym: "systema nervosum" RELATED LATIN [Wikipedia:Nervous_system] +synonym: "systema nervosum" RELATED OMO:0003011 [Wikipedia:Nervous_system] xref: AAO:0000324 xref: BILA:0000079 xref: BIRNLEX:844 @@ -9125,7 +9132,7 @@ xref: EHDAA2:0001246 xref: EHDAA:826 xref: EMAPA:16469 xref: EV:0100162 -xref: FBbt:00005093 +xref: FBbt:00005093 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:7157 xref: GAID:466 xref: MA:0000016 @@ -9156,6 +9163,7 @@ relationship: has_part CL:0000540 ! neuron relationship: immediate_transformation_of UBERON:0016880 {source="Bgee:AN"} ! future nervous system relationship: never_in_taxon NCBITaxon:6040 relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa +relationship: present_in_taxon NCBITaxon:9606 property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/b/b2/TE-Nervous_system_diagram.svg" xsd:anyURI property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/b/ba/Nervous_system_diagram.png" xsd:anyURI property_value: UBPROP:0000001 "A regulatory system of the body that consists of neurons and neuroglial cells. The nervous system is divided into two parts, the central nervous system (CNS) and the peripheral nervous system (PNS). (Source: BioGlossary, www.Biology-Text.com)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000396", ontology="TAO", source="ZFIN:curator"} @@ -9171,13 +9179,14 @@ namespace: uberon def: "The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the neural tube derivatives: the brain and spinal cord. In invertebrates it includes central ganglia plus nerve cord." [GO:0021551, http://www.frontiersinzoology.com/content/7/1/29, https://sourceforge.net/p/geneontology/ontology-requests/11422/] subset: cumbo subset: efo_slim +subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "cerebrospinal axis" NARROW [FMA:55675] synonym: "CNS" EXACT OMO:0003000 [] synonym: "neuraxis" RELATED [FMA:55675] -synonym: "systema nervosum centrale" EXACT LATIN [FMA:55675, FMA:TA] +synonym: "systema nervosum centrale" EXACT OMO:0003011 [FMA:55675, FMA:TA] xref: AAO:0000090 xref: BAMS:CNS xref: BILA:0000080 @@ -9190,7 +9199,7 @@ xref: EHDAA:828 xref: EMAPA:16470 xref: EMAPA:16754 xref: EV:0100163 -xref: FBbt:00005094 +xref: FBbt:00005094 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:55675 xref: GAID:570 xref: MA:0000167 @@ -9211,6 +9220,7 @@ relationship: immediate_transformation_of UBERON:0016879 {source="Bgee:AN"} ! fu relationship: never_in_taxon NCBITaxon:147099 {source="Wikipedia:Acoelomorpha"} relationship: only_in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of UBERON:0001016 ! nervous system +relationship: present_in_taxon NCBITaxon:9606 property_value: UBPROP:0000001 "Part of the nervous system which includes the brain and spinal cord.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000090", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000001 "The brain and spinal cord. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000012", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "The central nervous system (CNS) is the part of the nervous system which includes the brain, spinal cord, and nerve cell layer of the retina (CUMBO)." xsd:string {source="BIRNLEX:1099"} @@ -9224,8 +9234,8 @@ def: "Anatomical system that overlaps the nervous system and is responsible for subset: efo_slim subset: uberon_slim subset: vertebrate_core -synonym: "organa sensuum" EXACT LATIN [FMA:75259, FMA:TA] -synonym: "organa sensuum" RELATED LATIN [Wikipedia:Sensory_system] +synonym: "organa sensuum" EXACT OMO:0003011 [FMA:75259, FMA:TA] +synonym: "organa sensuum" RELATED OMO:0003011 [Wikipedia:Sensory_system] synonym: "sense organ subsystem" EXACT [] synonym: "sense organs" EXACT [FMA:75259] synonym: "sense organs set" EXACT [FMA:75259] @@ -9239,7 +9249,7 @@ xref: BILA:0000099 xref: EFO:0000805 xref: EHDAA2:0003094 xref: EMAPA:16192 -xref: FBbt:00007692 +xref: FBbt:00007692 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:75259 xref: MA:0002442 xref: MAT:0000031 @@ -9268,7 +9278,7 @@ subset: uberon_slim subset: vertebrate_core synonym: "neural primordium" RELATED [] synonym: "presumptive central nervous system" RELATED [] -synonym: "tubus neuralis" RELATED LATIN [Wikipedia:Neural_tube] +synonym: "tubus neuralis" RELATED OMO:0003011 [Wikipedia:Neural_tube] xref: AAO:0010617 xref: BTO:0001057 xref: CALOHA:TS-2371 @@ -9280,7 +9290,7 @@ xref: EMAPA:16164 xref: EMAPA:16757 xref: FMA:293882 xref: MAT:0000069 -xref: MESH:D054259 +xref: MESH:D054259 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: MIAA:0000069 xref: NCIT:C34226 xref: neuronames:1365 @@ -9316,7 +9326,7 @@ xref: BILA:0000000 xref: BIRNLEX:6 xref: CARO:0000000 xref: EHDAA2:0002229 -xref: FBbt:10000000 +xref: FBbt:10000000 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:62955 xref: HAO:0000000 xref: MA:0000001 @@ -9542,10 +9552,11 @@ xref: BTO:0000545 xref: EHDAA2:0000726 xref: EHDAA:518 xref: EMAPA:16247 -xref: FBbt:00003125 +xref: FBbt:00003125 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:45615 xref: galen:AlimentaryTract xref: MA:0000917 +xref: MESH:D041981 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} xref: NCIT:C34082 xref: TAO:0000112 xref: TGMA:0001819 @@ -9644,7 +9655,7 @@ xref: BILA:0000034 xref: BTO:0000174 xref: CALOHA:TS-2110 xref: EFO:0000461 -xref: FBbt:00004208 +xref: FBbt:00004208 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:69067 xref: GAID:407 xref: MESH:D004628 @@ -9794,7 +9805,7 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "embryonic notocord" EXACT [] -synonym: "notochorda" RELATED LATIN [Wikipedia:Notochord] +synonym: "notochorda" RELATED OMO:0003011 [Wikipedia:Notochord] synonym: "notocord" EXACT [ZFA:0000135] xref: AAO:0000327 xref: BTO:0001768 @@ -9853,7 +9864,7 @@ synonym: "epithelial somite" RELATED [https://github.com/obophenotype/uberon/wik synonym: "mesodermal cluster" BROAD [GO:0001756] synonym: "somites" RELATED OMO:0003004 [] synonym: "somitic mesoderm" RELATED [] -synonym: "somitus" RELATED LATIN [Wikipedia:Somite] +synonym: "somitus" RELATED OMO:0003011 [Wikipedia:Somite] xref: AAO:0010569 xref: AEO:0001015 xref: BTO:0001558 @@ -9923,7 +9934,7 @@ comment: Gene notes: Many factors and genes, such as Pax3 (Tremblay et al., 1995 subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "crista neuralis" RELATED LATIN [Wikipedia:Neural_crest] +synonym: "crista neuralis" RELATED OMO:0003011 [Wikipedia:Neural_crest] synonym: "NC" EXACT OMO:0003000 [XAO:0000048] synonym: "neural crest material" RELATED [VHOG:0000057] xref: AAO:0010578 @@ -9969,7 +9980,7 @@ namespace: uberon def: "Embryonic ectoderm that gives rise to nervous tissue." [Wikipedia:Neuroectoderm] subset: uberon_slim subset: vertebrate_core -synonym: "epithelium tubi neuralis; neuroectoderma" RELATED LATIN [Wikipedia:Neuroectoderm] +synonym: "epithelium tubi neuralis; neuroectoderma" RELATED OMO:0003011 [Wikipedia:Neuroectoderm] synonym: "neuaral ectoderm" RELATED [] synonym: "neural ectoderm" EXACT [] synonym: "neuroectoderm" EXACT [] @@ -9983,7 +9994,7 @@ xref: EHDAA:1498 xref: EHDAA:255 xref: EMAPA:16073 xref: EV:0100004 -xref: FBbt:00001057 +xref: FBbt:00001057 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:87657 xref: MAT:0000176 xref: MIAA:0000176 @@ -10010,7 +10021,7 @@ subset: organ_slim subset: pheno_slim subset: uberon_slim synonym: "ducted gland" EXACT [AEO:0000097] -synonym: "glandula exocrina" EXACT LATIN [Wikipedia:Exocrine_gland] +synonym: "glandula exocrina" EXACT OMO:0003011 [Wikipedia:Exocrine_gland] xref: AEO:0000097 xref: BTO:0000765 xref: CALOHA:TS-2012 @@ -10043,7 +10054,7 @@ subset: uberon_slim synonym: "ductless gland" EXACT [AEO:0000098] synonym: "ductless gland" RELATED [Wikipedia:Ductless_gland] synonym: "glandula endocrina" EXACT [] -synonym: "glandulae endocrinae" RELATED LATIN [Wikipedia:Endocrine_gland] +synonym: "glandulae endocrinae" RELATED OMO:0003011 [Wikipedia:Endocrine_gland] xref: AEO:0000098 xref: BTO:0001488 xref: CALOHA:TS-1300 @@ -10074,8 +10085,8 @@ subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "medulla of bone" RELATED [BTO:0000141] -synonym: "medulla ossea" EXACT LATIN [BTO:0000141, FMA:9608] -synonym: "medulla ossium" EXACT LATIN [BTO:0000141, Wikipedia:Bone_marrow] +synonym: "medulla ossea" EXACT OMO:0003011 [BTO:0000141, FMA:9608] +synonym: "medulla ossium" EXACT OMO:0003011 [BTO:0000141, Wikipedia:Bone_marrow] synonym: "medullary bone" RELATED [] xref: AAO:0011007 xref: BTO:0000141 @@ -10310,7 +10321,7 @@ subset: efo_slim subset: pheno_slim subset: uberon_slim synonym: "Druese" RELATED [BTO:0000522] -synonym: "glandula" RELATED LATIN [BTO:0000522, Wikipedia:Gland] +synonym: "glandula" RELATED OMO:0003011 [BTO:0000522, Wikipedia:Gland] synonym: "glandular organ" EXACT [http://orcid.org/0000-0002-6601-2165] xref: AAO:0000212 xref: AEO:0000096 @@ -10321,7 +10332,7 @@ xref: EHDAA:2161 xref: EHDAA:4475 xref: EHDAA:6522 xref: EMAPA:18425 -xref: FBbt:00100317 +xref: FBbt:00100317 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:7146 xref: FMA:86294 xref: galen:Gland @@ -10354,7 +10365,7 @@ subset: vertebrate_core synonym: "blastocyst" RELATED [] synonym: "ectoblast" RELATED [MP:0003886] synonym: "epiblast" EXACT [VHOG:0000243] -synonym: "epiblastus" RELATED LATIN [Wikipedia:Epiblast] +synonym: "epiblastus" RELATED OMO:0003011 [Wikipedia:Epiblast] synonym: "primitive ectoderm" RELATED [VHOG:0000243] xref: BTO:0004593 xref: FMA:296704 @@ -10482,7 +10493,7 @@ def: "A region of embryonic ectodermal cells that lie directly above the notocho subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "lamina neuralis" RELATED LATIN [Wikipedia:Neural_plate] +synonym: "lamina neuralis" RELATED OMO:0003011 [Wikipedia:Neural_plate] synonym: "presumptive central nervous system" RELATED [] xref: AAO:0011072 xref: BTO:0001765 @@ -10492,7 +10503,7 @@ xref: EHDAA:346 xref: EHDAA:902 xref: EMAPA:35593 xref: FMA:293879 -xref: MESH:D054258 +xref: MESH:D054258 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: NCIT:C34225 xref: neuronames:1362 xref: RETIRED_EHDAA2:0001252 @@ -10520,7 +10531,7 @@ def: "The paraxial mesoderm is the mesoderm located bilaterally adjacent to the subset: efo_slim subset: uberon_slim subset: vertebrate_core -synonym: "mesoderma paraxiale" RELATED LATIN [Wikipedia:Paraxial_mesoderm] +synonym: "mesoderma paraxiale" RELATED OMO:0003011 [Wikipedia:Paraxial_mesoderm] synonym: "paraxial mesenchyme" EXACT [https://github.com/obophenotype/uberon/issues/30, https://github.com/obophenotype/uberon/wiki/The-neural-crest, ZFA:0000255] synonym: "somitic mesoderm" EXACT [ISBN:9780878932504] xref: AAO:0010568 @@ -10559,7 +10570,7 @@ synonym: "lateral mesoderm" EXACT [GO:0048368] synonym: "lateral plate" RELATED [] synonym: "lateral plate mesenchyme" RELATED [EHDAA2:0000919] synonym: "LPM" EXACT OMO:0003000 [ZFA:0000121] -synonym: "mesoderma laminae lateralis" RELATED LATIN [Wikipedia:Lateral_plate_mesoderm] +synonym: "mesoderma laminae lateralis" RELATED OMO:0003011 [Wikipedia:Lateral_plate_mesoderm] xref: AAO:0010574 xref: EHDAA2:0000919 xref: EHDAA:379 @@ -10599,7 +10610,7 @@ synonym: "myomere" RELATED [] synonym: "myomeres" EXACT OMO:0003004 [TAO:0001056] synonym: "myotome region" RELATED [] synonym: "myotomes" RELATED [] -synonym: "myotomus" RELATED LATIN [Wikipedia:Myotome] +synonym: "myotomus" RELATED OMO:0003011 [Wikipedia:Myotome] xref: AAO:0011067 xref: AEO:0001018 xref: BTO:0000742 @@ -10657,7 +10668,7 @@ def: "Portion of tissue composed of mesenchymal cells (motile cells that develop subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "mesenchyma" RELATED LATIN [Wikipedia:Mesenchyme] +synonym: "mesenchyma" RELATED OMO:0003011 [Wikipedia:Mesenchyme] synonym: "mesenchymal tissue" EXACT [] synonym: "mesenchyme tissue" EXACT [] synonym: "portion of mesenchymal tissue" EXACT [] @@ -10714,7 +10725,7 @@ def: "Epithelial tubes transport gases, liquids and cells from one site to anoth synonym: "epithelial or endothelial tube" EXACT [] xref: AEO:0000114 xref: EHDAA2:0003114 -xref: FBbt:00007474 +xref: FBbt:00007474 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0000025 ! tube is_a: UBERON:0000483 ! epithelium intersection_of: UBERON:0000483 ! epithelium @@ -10891,7 +10902,7 @@ synonym: "trilaminar disk" RELATED [https://orcid.org/0000-0002-6601-2165] synonym: "trilaminar germ" RELATED [https://orcid.org/0000-0002-6601-2165] xref: BILA:0000060 xref: BTO:0001403 -xref: FBbt:00005317 +xref: FBbt:00005317 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:293108 xref: GAID:1302 xref: MESH:D005775 @@ -10995,7 +11006,7 @@ namespace: uberon def: "Anatomical structure that connects two or more adjacent skeletal elements or hardened body parts." [http://orcid.org/0000-0002-6601-2165] subset: grouping_class synonym: "joint" NARROW [] -xref: FBbt:00005811 +xref: FBbt:00005811 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0034921 ! multi organ part structure relationship: part_of UBERON:0004770 ! articular system @@ -11011,7 +11022,7 @@ synonym: "gut section" RELATED [FBbt:00100315] synonym: "intestinal tract" RELATED [] synonym: "segment of intestinal tract" RELATED [] synonym: "subdivision of alimentary system" RELATED [FMA:71131] -xref: FBbt:00100315 +xref: FBbt:00100315 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:71131 is_a: UBERON:0013522 ! subdivision of tube intersection_of: UBERON:0013522 ! subdivision of tube @@ -11153,7 +11164,7 @@ name: photoreceptor array namespace: uberon def: "An array of photoreceptors and any supporting cells found in an eye." [https://orcid.org/0000-0002-6601-2165] synonym: "light-sensitive tissue" EXACT [] -xref: FBbt:00004200 +xref: FBbt:00004200 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0004923 ! organ component layer intersection_of: UBERON:0004923 ! organ component layer intersection_of: composed_primarily_of CL:0000210 ! photoreceptor cell @@ -11173,7 +11184,7 @@ synonym: "developmental tissue" RELATED [MIAA:0000019] xref: AEO:0000125 xref: CALOHA:TS-2122 xref: EHDAA2:0003125 -xref: FBbt:00007006 +xref: FBbt:00007006 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:292313 xref: MIAA:0000019 is_a: UBERON:0000465 ! material anatomical entity @@ -11204,7 +11215,7 @@ namespace: uberon def: "An acellular membrane that is part of the epithelium, lies adjacent to the epithelial cells, and is the fusion of the the basal lamina and the reticular lamina." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Basement_membrane] synonym: "basement membrane" RELATED [FMA:63872] synonym: "basement membrane of connective tissue" EXACT [FMA:63872] -synonym: "membrana basalis" EXACT LATIN [Wikipedia:Basement_membrane] +synonym: "membrana basalis" EXACT OMO:0003011 [Wikipedia:Basement_membrane] xref: AAO:0010596 xref: FMA:63872 xref: GAID:915 @@ -11569,7 +11580,7 @@ subset: common_anatomy subset: upper_level synonym: "multicellular structure" EXACT [FBbt:00100313] xref: CARO:0010000 -xref: FBbt:00100313 +xref: FBbt:00100313 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0000061 ! anatomical structure intersection_of: UBERON:0000061 ! anatomical structure intersection_of: has_quality PATO:0001993 ! multicellular @@ -11626,8 +11637,9 @@ name: organ system subdivision namespace: uberon def: "A subdivision of an anatomical system." [http://orcid.org/0000-0002-6601-2165] subset: common_anatomy +subset: human_reference_atlas subset: upper_level -xref: FBbt:00007330 +xref: FBbt:00007330 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:67509 xref: SCTID:91690000 is_a: UBERON:0010000 {source="FBbt"} ! multicellular anatomical structure @@ -11635,6 +11647,7 @@ relationship: part_of UBERON:0000467 ! anatomical system relationship: present_in_taxon NCBITaxon:33090 relationship: present_in_taxon NCBITaxon:33208 ! Metazoa relationship: present_in_taxon NCBITaxon:4751 +relationship: present_in_taxon NCBITaxon:9606 [Term] id: UBERON:0011676 @@ -11803,7 +11816,6 @@ id: UBERON:0013702 name: body proper namespace: uberon def: "The region of the organism associated with the visceral organs." [AEO:0000103] -subset: human_reference_atlas subset: non_informative synonym: "body" RELATED [AEO:0000103] synonym: "whole body" RELATED [BTO:0001489] @@ -11813,7 +11825,6 @@ xref: EMAPA:36031 xref: FMA:231424 is_a: UBERON:0000475 {source="AEO"} ! organism subdivision relationship: part_of UBERON:0013701 ! main body axis -relationship: present_in_taxon NCBITaxon:9606 property_value: UBPROP:0000001 "Cardinal body part, which consists of a maximal set of diverse subclasses of organ and organ part spatially associated with the vertebral column and ribcage. Examples: There is only one body proper[FMA:231424]." xsd:string {source="FMA:231424"} [Term] @@ -11821,6 +11832,7 @@ id: UBERON:0014892 name: skeletal muscle organ, vertebrate namespace: uberon def: "A muscle organ that consists of skeletal muscle tissue ensheathed in epimysium, that develops from myotome and that is innervated by some somatic motor neuron. Skeletal muscles are typically attached (via a tendon) to a bone but there are exceptions (e.g. intrinsic tongue muscles)." [GOC:dos] +subset: human_reference_atlas synonym: "skeletal muscle" BROAD [] xref: AAO:0011099 xref: BTO:0001103 @@ -11851,6 +11863,7 @@ relationship: composed_primarily_of UBERON:0001134 ! skeletal muscle tissue relationship: develops_from UBERON:0003082 ! myotome relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of UBERON:0018254 ! skeletal musculature +relationship: present_in_taxon NCBITaxon:9606 relationship: surrounded_by UBERON:0011899 ! epimysium relationship: synapsed_by CL:0000100 ! motor neuron @@ -11860,7 +11873,7 @@ name: non-connected functional system namespace: uberon def: "An anatomical group whose component structures share a common function." [AEO:0000093, AEO:JB, FBbt:00007278, FBC:DOS] xref: AEO:0000093 -xref: FBbt:00007278 +xref: FBbt:00007278 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0034923 ! disconnected anatomical group [Term] @@ -11980,12 +11993,14 @@ id: UBERON:0018254 name: skeletal musculature namespace: uberon subset: grouping_class +subset: human_reference_atlas xref: EHDAA2:0001842 xref: EMAPA:35578 xref: MA:0000165 is_a: UBERON:0000061 ! anatomical structure relationship: composed_primarily_of UBERON:0014892 ! skeletal muscle organ, vertebrate relationship: part_of UBERON:0000383 {source="MA"} ! musculature of body +relationship: present_in_taxon NCBITaxon:9606 property_value: editor_note "Added for consistency with MA EMAPA and EHDAA2. See https://github.com/obophenotype/mouse-anatomy-ontology/issues/104" xsd:string [Term] @@ -12017,7 +12032,7 @@ namespace: uberon def: "Material anatomical entity consisting of multiple anatomical structures that are not connected to each other." [CARO:0020000] subset: common_anatomy xref: CARO:0020000 -xref: FBbt:00007276 +xref: FBbt:00007276 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0000465 {source="CARO"} ! material anatomical entity relationship: composed_primarily_of UBERON:0000061 ! anatomical structure relationship: has_component UBERON:0000061 {minCardinality="2"} ! anatomical structure @@ -12467,20 +12482,6 @@ property_value: seeAlso "https://github.com/obophenotype/uberon/wiki/Part-disjoi is_a: RO:0002323 ! mereotopologically related to expand_expression_to: "BFO_0000051 exactly 0 (BFO_0000050 some ?Y)" [] -[Typedef] -id: RO:0002203 -name: develops into -def: "inverse of develops from" [] -subset: RO:0002259 -property_value: IAO:0000114 IAO:0000125 -property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 -property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172 -property_value: IAO:0000117 https://orcid.org/0000-0003-1980-3228 -is_transitive: true -is_a: has_potential_to_develop_into ! has potential to develop into -is_a: RO:0002286 ! developmentally succeeded by -is_a: RO:0002388 ! has potential to directly develop into - [Typedef] id: RO:0002206 name: expressed in @@ -12501,7 +12502,7 @@ def: "inverse of directly develops from" [] subset: RO:0002259 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000118 "developmental precursor of" xsd:string -is_a: RO:0002203 ! develops into +is_a: develops_into ! develops into [Typedef] id: RO:0002222 @@ -12531,7 +12532,7 @@ def: "inverse of has developmental contribution from" [] subset: RO:0002259 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 -holds_over_chain: RO:0002203 part_of +holds_over_chain: develops_into part_of is_a: has_potential_to_developmentally_contribute_to ! has potential to developmentally contribute to is_a: RO:0002286 ! developmentally succeeded by @@ -13817,7 +13818,7 @@ range: BFO:0000004 ! independent continuant is_transitive: true is_a: has_developmental_contribution_from ! has developmental contribution from is_a: RO:0002258 ! developmentally preceded by -inverse_of: RO:0002203 ! develops into +inverse_of: develops_into ! develops into [Typedef] id: develops_from_part_of @@ -13844,6 +13845,22 @@ domain: UBERON:0001062 ! anatomical entity holds_over_chain: directly_develops_from located_in is_a: RO:0002258 ! developmentally preceded by +[Typedef] +id: develops_into +name: develops into +namespace: uberon +def: "inverse of develops from" [] +subset: RO:0002259 +xref: RO:0002203 +property_value: IAO:0000114 IAO:0000125 +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 +property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172 +property_value: IAO:0000117 https://orcid.org/0000-0003-1980-3228 +is_transitive: true +is_a: has_potential_to_develop_into ! has potential to develop into +is_a: RO:0002286 ! developmentally succeeded by +is_a: RO:0002388 ! has potential to directly develop into + [Typedef] id: directly_develops_from name: directly develops from @@ -14178,7 +14195,7 @@ is_a: RO:0002479 ! has part that occurs in id: has_high_plasma_membrane_amount name: obsolete has_high_plasma_membrane_amount def: "OBSOLETE A relation between a cell and molecule or complex such that every instance of the cell has a high number of instances of that molecule expressed on the cell surface. For the formal definition, see Masci et al (PMID:19243617)." [PMID:19243617] -comment: Replaced with RO:0015015, see https://github.com/obophenotype/cell-ontology/issues/1481 +property_value: term_tracker_item https://github.com/obophenotype/cell-ontology/issues/1481 is_obsolete: true replaced_by: RO:0015015 @@ -14205,7 +14222,7 @@ inverse_of: input_of ! input of id: has_low_plasma_membrane_amount name: obsolete has_low_plasma_membrane_amount def: "OBSOLETE A relation between a cell and molecule or complex such that every instance of the cell has a low number of instances of that molecule expressed on the cell surface. For the formal definition, see Masci et al (PMID:19243617)." [PMID:19243617] -comment: Replaced with RO:0015016, see https://github.com/obophenotype/cell-ontology/issues/1481 +property_value: term_tracker_item https://github.com/obophenotype/cell-ontology/issues/1481 is_obsolete: true replaced_by: RO:0015016 @@ -15591,21 +15608,21 @@ is_a: develops_from ! develops from id: transitively_anteriorly_connected_to name: transitively anteriorly connected to namespace: uberon -def: "." [http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern] +property_value: seeAlso "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" xsd:anyURI is_transitive: true [Typedef] id: transitively_distally_connected_to name: transitively distally connected to namespace: uberon -def: "." [http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern] +property_value: seeAlso "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" xsd:anyURI is_transitive: true [Typedef] id: transitively_proximally_connected_to name: transitively proximally connected to namespace: uberon -def: "." [http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern] +property_value: seeAlso "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" xsd:anyURI is_transitive: true [Typedef] diff --git a/src/ontology/subsets/general_cell_types_upper_slim.owl b/src/ontology/subsets/general_cell_types_upper_slim.owl index af2ba343e..48fbe975e 100644 --- a/src/ontology/subsets/general_cell_types_upper_slim.owl +++ b/src/ontology/subsets/general_cell_types_upper_slim.owl @@ -18,6 +18,7 @@ xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#" xmlns:skos="http://www.w3.org/2004/02/skos/core#" xmlns:swrl="http://www.w3.org/2003/11/swrl#" + xmlns:sssom="https://w3id.org/sssom/" xmlns:swrla="http://swrl.stanford.edu/ontologies/3.3/swrla.owl#" xmlns:swrlb="http://www.w3.org/2003/11/swrlb#" xmlns:terms="http://purl.org/dc/terms/" @@ -29,8 +30,8 @@ xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#" xmlns:ncbitaxon="http://purl.obolibrary.org/obo/ncbitaxon#"> - - 2024-01-04 + + 2024-02-13 @@ -315,6 +316,14 @@ Annotations: IAO_0000424 "http://purl.obolibrary.org/obo/BFO_0000051 some ( + + + + + + + + @@ -337,6 +346,14 @@ Annotations: IAO_0000424 "http://purl.obolibrary.org/obo/BFO_0000051 some ( + + + + + + + + @@ -846,25 +863,25 @@ WHERE { - + - + - + - + - + - + @@ -1071,14 +1088,6 @@ WHERE { - - - - - - - - @@ -1103,14 +1112,6 @@ WHERE { - - - - - - - - @@ -1942,6 +1943,24 @@ WHERE { + + + + + + + + + + + + + + + + + + - - - - - - - - - - - - - - - - - - - - - A nucleus size quality which is relatively high compared to the amount of cytoplasm present in the same cell. - - 2009-12-23T10:53:24Z - increased nucleus size - - - - - A nucleus size quality which is relatively high compared to the amount of cytoplasm present in the same cell. - GOC:tfm - - - - @@ -15340,7 +15381,7 @@ For example, A and B may be gene products and binding of B by A positively regul - A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex). + A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex). https://github.com/geneontology/go-ontology/issues/17729 GO:0008372 NIF_Subcellular:sao1337158144 @@ -15361,7 +15402,7 @@ For example, A and B may be gene products and binding of B by A positively regul - A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex). + A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex). GOC:pdt @@ -15391,8 +15432,8 @@ For example, A and B may be gene products and binding of B by A positively regul + - Note that this term is intended to annotate gene products that are not attached to the cell surface. For gene products from multicellular organisms which are secreted from a cell but retained within the organism (i.e. released into the interstitial fluid or blood), consider the cellular component term 'extracellular space ; GO:0005615'. extracellular region @@ -15409,32 +15450,32 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + A protein complex consisting of three collagen chains assembled into a left-handed triple helix. These trimers typically assemble into higher order structures. Wikipedia:Collagen cellular_component GO:0005581 collagen trimer - + - + - + PMID:12382326 - + PMID:12382326 @@ -15625,8 +15666,8 @@ For example, A and B may be gene products and binding of B by A positively regul + - Chromosomes include parts that are not part of the chromatin. Examples include the kinetochore. chromosome @@ -15692,8 +15733,8 @@ For example, A and B may be gene products and binding of B by A positively regul + - cytoplasm @@ -15822,8 +15863,8 @@ For example, A and B may be gene products and binding of B by A positively regul + - plasma membrane @@ -15920,8 +15961,8 @@ For example, A and B may be gene products and binding of B by A positively regul + - DNA recombination @@ -15953,7 +15994,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Note that this term should not be used for direct annotation. It should be possible to make a more specific annotation to one of the children of this term, for e.g. to transmembrane transport, to microtubule-based transport or to vesicle-mediated transport. transport @@ -18047,8 +18088,8 @@ For example, A and B may be gene products and binding of B by A positively regul + - Note that a signal is any variable property or parameter that serves to convey information, and may be a physical entity such as a gene product or small molecule, a photon, or a change in state such as movement or voltage change. signaling @@ -18201,7 +18242,7 @@ For example, A and B may be gene products and binding of B by A positively regul cell projection organization and biogenesis cell surface structure organization and biogenesis GO:0030030 - + cell projection organization @@ -18746,7 +18787,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + extracellular matrix @@ -19709,7 +19750,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + cell projection @@ -19796,6 +19837,7 @@ For example, A and B may be gene products and binding of B by A positively regul The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. + https://github.com/geneontology/go-ontology/issues/26424 GO:0034960 GO:0043283 GO:0044259 @@ -19805,6 +19847,7 @@ For example, A and B may be gene products and binding of B by A positively regul multicellular organismal macromolecule metabolic process biological_process GO:0043170 + macromolecule metabolic process @@ -19854,7 +19897,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + organelle @@ -20180,7 +20223,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. GO:0002226 Wikipedia:Innate_immune_system @@ -21006,9 +21049,11 @@ For example, A and B may be gene products and binding of B by A positively regul The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. + https://github.com/geneontology/go-ontology/issues/26424 development of an anatomical structure biological_process GO:0048856 + @@ -21056,7 +21101,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + cell motility @@ -21385,7 +21430,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. response to stimulus @@ -21969,7 +22014,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + membrane organization @@ -22201,6 +22246,7 @@ For example, A and B may be gene products and binding of B by A positively regul The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon. + https://github.com/geneontology/go-ontology/issues/26424 mah 2010-03-08T03:32:18Z organic molecular entity metabolic process @@ -22208,6 +22254,7 @@ For example, A and B may be gene products and binding of B by A positively regul organic substance metabolism biological_process GO:0071704 + organic substance metabolic process @@ -22261,7 +22308,7 @@ For example, A and B may be gene products and binding of B by A positively regul - The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures. + The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures. mah 2010-10-04T01:51:47Z cellular_component @@ -22272,7 +22319,7 @@ For example, A and B may be gene products and binding of B by A positively regul - The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures. + The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures. GOC:pdt @@ -22491,7 +22538,7 @@ For example, A and B may be gene products and binding of B by A positively regul biological_process GO:0098542 - + defense response to other organism @@ -23161,6 +23208,7 @@ For example, A and B may be gene products and binding of B by A positively regul A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex but below that of an anatomical system. Or, a substance produced by a cellular organism with granularity above the level of a protein complex. https://github.com/geneontology/go-ontology/issues/24200 + https://github.com/geneontology/go-ontology/issues/26424 kmv 2019-08-12T18:01:37Z cellular_component @@ -23341,6 +23389,27 @@ For example, A and B may be gene products and binding of B by A positively regul + + + + + Reactions triggered in response to the presence of a symbiont that act to protect or prevent damage to the host. + https://github.com/geneontology/go-ontology/issues/20261 + pg + 2020-11-11T17:19:06Z + biological_process + GO:0140546 + defense response to symbiont + + + + + Reactions triggered in response to the presence of a symbiont that act to protect or prevent damage to the host. + GOC:pg + + + + @@ -24419,57 +24488,6 @@ For example, A and B may be gene products and binding of B by A positively regul - - - - - quality - PATO:0000068 - TODO: define this or obsolete it and move children somewhere else. - qualitative - - - - - - - - - A quality inhering in a bearer by virtue of the whether the bearer differs from normal or average. - quality - PATO:0000069 - - deviation (from_normal) - - - - - A quality inhering in a bearer by virtue of the whether the bearer differs from normal or average. - PATOC:GVG - - - - - - - - - A morphology quality inhering in a bearer by virtue of the bearer's physical magnitude. - quality - PATO:0000117 - - - size - - - - - A morphology quality inhering in a bearer by virtue of the bearer's physical magnitude. - WordNet:WordNet - - - - @@ -24521,67 +24539,6 @@ For example, A and B may be gene products and binding of B by A positively regul - - - - - A quality inhering in a bearer by virtue of the bearer's exhibiting no deviation from normal or average. - - quality - average - PATO:0000461 - - - - normal - - - - - A quality inhering in a bearer by virtue of the bearer's exhibiting no deviation from normal or average. - PATOC:GVG - - - - - - - - - - - - - - - - - - - - - A size quality which is relatively high. - - PATO:0001202 - quality - big - enlarged - expanded - great - large - PATO:0000586 - - increased size - - - - - A size quality which is relatively high. - PATOC:GVG - - - - @@ -25172,77 +25129,6 @@ For example, A and B may be gene products and binding of B by A positively regul - - - - - - - - - - - - - - - - - - - - - - A quality that has a value that is increased compared to normal or average. - - - 2011-06-16T06:39:43Z - quality - PATO:0002300 - increased quality - - - - - A quality that has a value that is increased compared to normal or average. - PATOC:GVG - - - - - - - - - - - - - - - - - - - - - A quality of an object that has a value that is increased compared to normal or average. - - - 2011-06-16T06:54:01Z - quality - PATO:0002305 - increased object quality - - - - - A quality of an object that has a value that is increased compared to normal or average. - PATOC:GVG - - - - @@ -25372,6 +25258,28 @@ For example, A and B may be gene products and binding of B by A positively regul + + + + + A quality inhering in a cell by virtue of the cell having a high nuclear/cytoplasmic ratio. + http://orcid.org/0000-0001-5208-3432 + high N:C ratio + quality + PATO:0040072 + A high nuclear/cytolasmic ratio is 70% or higher. + high nuclear/cytoplasmic ratio + + + + + A quality inhering in a cell by virtue of the cell having a high nuclear/cytoplasmic ratio. + Wikipedia:NC_ratio&oldid=931936284 + http://lymerick.net/blood-cells.pdf + + + + @@ -27700,6 +27608,12 @@ For example, A and B may be gene products and binding of B by A positively regul https://github.com/obophenotype/uberon/issues/549 https://orcid.org/0000-0002-6601-2165 + + + + FBbt:00005155 + + @@ -27807,8 +27721,8 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + @@ -27859,11 +27773,11 @@ For example, A and B may be gene products and binding of B by A positively regul tendon http://upload.wikimedia.org/wikipedia/commons/3/3c/Achilles-tendon.jpg - + - + @@ -27876,13 +27790,13 @@ For example, A and B may be gene products and binding of B by A positively regul - + OG - + AEO @@ -27936,7 +27850,7 @@ For example, A and B may be gene products and binding of B by A positively regul tendo Wikipedia:Tendon - + @@ -28000,6 +27914,12 @@ For example, A and B may be gene products and binding of B by A positively regul A tube shaped portion of tissue lined with epithelial cells that collects secretions and routes them to their destination[ZFA:0005171]. ZFA:0005171 + + + + FBbt:00100314 + + @@ -28121,6 +28041,12 @@ For example, A and B may be gene products and binding of B by A positively regul Material anatomical entity that is a single connected structure with inherent 3D shape generated by coordinated expression of the organism's own genome. CARO:0000003 + + + + FBbt:00007001 + + @@ -28730,7 +28656,9 @@ For example, A and B may be gene products and binding of B by A positively regul IDOMAL:0000302 - https://orcid.org/0000-0003-4423-4370 + + + https://github.com/biopragmatics/biomappings @@ -28755,7 +28683,7 @@ For example, A and B may be gene products and binding of B by A positively regul zygotum Wikipedia:Zygote - + @@ -28879,7 +28807,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -28915,14 +28843,14 @@ For example, A and B may be gene products and binding of B by A positively regul gastrula stage - + - + BILS @@ -29200,6 +29128,12 @@ For example, A and B may be gene products and binding of B by A positively regul in FMA, the tongue, palate etc are part of the mouth which is itself a subdivision of the face. ZFA includes a separate class 'oral region' which is part of the mouth, but excludes tongue and lips FMA + + + + FBbt:00003126 + + @@ -29207,14 +29141,14 @@ For example, A and B may be gene products and binding of B by A positively regul BTO:0004698 FMA:49184 FMA:TA - + cavital oralis Wikipedia:Mouth - + @@ -29474,7 +29408,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -29516,14 +29450,14 @@ For example, A and B may be gene products and binding of B by A positively regul organism substance - + - + this relationship may be too strong and may be weakened in future @@ -29532,6 +29466,12 @@ For example, A and B may be gene products and binding of B by A positively regul Material anatomical entity in a gaseous, liquid, semisolid or solid state; produced by anatomical structures or derived from inhaled and ingested substances that have been modified by anatomical structures as they pass through the body. http://orcid.org/0000-0001-9114-8737 + + + + FBbt:00007019 + + @@ -29610,6 +29550,12 @@ For example, A and B may be gene products and binding of B by A positively regul Non-material anatomical entity of three dimensions, that is generated by morphogenetic or other physiologic processes; is surrounded by one or more anatomical structures; contains one or more organism substances or anatomical structures. http://orcid.org/0000-0001-9114-8737 + + + + FBbt:00007017 + + @@ -29659,6 +29605,12 @@ For example, A and B may be gene products and binding of B by A positively regul Anatomical entity that has mass. http://orcid.org/0000-0001-9114-8737 + + + + FBbt:00007016 + + @@ -29695,6 +29647,12 @@ For example, A and B may be gene products and binding of B by A positively regul Anatomical entity that has no mass. http://orcid.org/0000-0001-9114-8737 + + + + FBbt:00007015 + + @@ -29780,11 +29738,19 @@ For example, A and B may be gene products and binding of B by A positively regul system GO:0048731 + + + + FBbt:00004856 + + IDOMAL:0002460 - https://orcid.org/0000-0003-4423-4370 + + + https://github.com/biopragmatics/biomappings @@ -29883,6 +29849,12 @@ For example, A and B may be gene products and binding of B by A positively regul VHOG:0000671 WBbt:0007833 + + + + FBbt:00000001 + + @@ -29986,6 +29958,12 @@ For example, A and B may be gene products and binding of B by A positively regul CARO:DOS http://orcid.org/0000-0001-9114-8737 + + + + FBbt:00007009 + + @@ -30053,6 +30031,12 @@ For example, A and B may be gene products and binding of B by A positively regul Anatomical structure that consists of cell parts and cell substances and together does not constitute a cell or a tissue. http://orcid.org/0000-0001-9114-8737 + + + + FBbt:00007013 + + @@ -30072,7 +30056,6 @@ For example, A and B may be gene products and binding of B by A positively regul FBbt:00007277 - IDOMAL:0002461 VHOG:0001737 uberon UBERON:0000477 @@ -30089,8 +30072,8 @@ For example, A and B may be gene products and binding of B by A positively regul - IDOMAL:0002461 - https://orcid.org/0000-0003-4423-4370 + FBbt:00007277 + @@ -30154,6 +30137,12 @@ For example, A and B may be gene products and binding of B by A positively regul http://orcid.org/0000-0001-9114-8737 https://cedar.bio.indiana.edu/trac/env/ontologies/ticket/279 + + + + FBbt:00005835 + + @@ -30236,6 +30225,12 @@ For example, A and B may be gene products and binding of B by A positively regul Multicellular anatomical structure that consists of many cells of one or a few types, arranged in an extracellular matrix such that their long-range organisation is at least partly a repetition of their short-range organisation. CARO:0000043 + + + + FBbt:00007003 + + @@ -30303,6 +30298,12 @@ For example, A and B may be gene products and binding of B by A positively regul CARO:0000055 http://orcid.org/0000-0001-9114-8737 + + + + FBbt:00007010 + + @@ -30349,7 +30350,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -30393,14 +30394,14 @@ For example, A and B may be gene products and binding of B by A positively regul epithelium https://upload.wikimedia.org/wikipedia/commons/8/8f/Illu_epithelium.jpg - + - + http://palaeos.com/metazoa/porifera/homoscleromorpha.html @@ -30420,6 +30421,12 @@ For example, A and B may be gene products and binding of B by A positively regul ISBN:978-0030259821 Ruppert EE, Fox RS, Barnes RD, Invertebrate zoology: a functional evolutionary approach (2003) p.59 http://bgee.unil.ch/ + + + + FBbt:00007005 + + @@ -30654,11 +30661,19 @@ For example, A and B may be gene products and binding of B by A positively regul Obsoleted in ZFA. Note that embryo is not classified as an embryonic structure - an embryonic structure is only the parts of an embryo ZFA + + + + FBbt:00000052 + + IDOMAL:0000646 - https://orcid.org/0000-0003-4423-4370 + + + https://github.com/biopragmatics/biomappings @@ -30745,6 +30760,12 @@ For example, A and B may be gene products and binding of B by A positively regul embryonic tissue FMA:69069 + + + + FBbt:00000110 + + @@ -30783,7 +30804,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Primary germ layer that is the outer of the embryo's three germ layers and gives rise to epidermis and neural tissue. Primary germ layer that is the outer of the embryonic germ layers and gives rise to epidermis and neural tissue.[AAO] The Bilateria are triploblastic (with true endoderm, mesoderm, and ectoderm) (...).[well established][VHOG] @@ -30821,14 +30842,14 @@ For example, A and B may be gene products and binding of B by A positively regul ectoderm http://upload.wikimedia.org/wikipedia/commons/1/19/Gray32.png - + - + Bgee:AN @@ -30856,6 +30877,12 @@ For example, A and B may be gene products and binding of B by A positively regul ISBN:978-0878932504 Gilbert SF, Developmental Biology (2006) Limb development and evolution, p.722 http://bgee.unil.ch/ + + + + FBbt:00000111 + + @@ -30881,7 +30908,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Primary germ layer that lies remote from the surface of the embryo and gives rise to internal tissues such as gut. The Bilateria are triploblastic (with true endoderm, mesoderm, and ectoderm) (...).[well established][VHOG] endodermal @@ -30918,14 +30945,14 @@ For example, A and B may be gene products and binding of B by A positively regul http://upload.wikimedia.org/wikipedia/commons/c/c0/Endoderm2.png http://upload.wikimedia.org/wikipedia/commons/d/df/Gray10.png - + - + Bgee:AN @@ -30944,6 +30971,12 @@ For example, A and B may be gene products and binding of B by A positively regul ISBN:978-0878932504 Gilbert SF, Developmental Biology (2006) Limb development and evolution, p.722 http://bgee.unil.ch/ + + + + FBbt:00000125 + + @@ -30970,7 +31003,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + The middle germ layer of the embryo, between the endoderm and ectoderm. Primary germ layer that is the middle of the embryonic germ layers.[AAO] @@ -31015,7 +31048,7 @@ For example, A and B may be gene products and binding of B by A positively regul mesoderm http://upload.wikimedia.org/wikipedia/commons/e/e8/Mesoderm.png - + @@ -31028,7 +31061,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Bgee:AN @@ -31062,6 +31095,12 @@ For example, A and B may be gene products and binding of B by A positively regul sponges do not seem to have a mesoderm and accordingly Amphimedon lacks transcription factors involved in mesoderm development (Fkh, Gsc, Twist, Snail)[http://www.nature.com/nature/journal/v466/n7307/full/nature09201.html]. Mesoderm may not be homologous across verteberates https://github.com/obophenotype/uberon/wiki/The-neural-crest + + + + FBbt:00000126 + + @@ -31171,6 +31210,12 @@ For example, A and B may be gene products and binding of B by A positively regul stomodeal-hypophyseal primordium XAO:0000269 + + + + FBbt:00000439 + + @@ -31308,6 +31353,12 @@ For example, A and B may be gene products and binding of B by A positively regul DOI:10.1073/pnas.0812138106 Markov GV, Tavares R, Dauphin-Villemant C, Demeneix BA, Baker ME, Laudet V, Independent elaboration of steroid hormone signaling pathways in metazoans. PNAS (2009) http://bgee.unil.ch/ + + + + FBbt:00005068 + + @@ -31333,8 +31384,8 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + @@ -31370,24 +31421,24 @@ For example, A and B may be gene products and binding of B by A positively regul eye - + - + - + PMID:21062451 - + PMID:21062451 @@ -31396,6 +31447,12 @@ For example, A and B may be gene products and binding of B by A positively regul An organ that detects light. https://orcid.org/0000-0002-6601-2165 + + + + FBbt:00005162 + + @@ -31620,6 +31677,12 @@ For example, A and B may be gene products and binding of B by A positively regul many anatomy ontologies consider gastrointestinal system synonymous with digestive system. here we follow MA in dividing digestive system into gastrointestinal and hepatobiliary. hepatobiliary includes the liver and biliary tract. species-specific AO classes are categorized according to whether liver is included. For example, XAO includes liver as part of XAO:0000125 alimentary system, so we assume this class is the more generic class MA + + + + FBbt:00005055 + + @@ -31663,6 +31726,7 @@ For example, A and B may be gene products and binding of B by A positively regul We should divest ourselves of the view that earlier vertebrate groups were 'on their way' to becoming mammals, as clearly they were not such visionaries. Neither were their systems 'imperfect' as earlier anatomists thought. Instead, their circulatory systems served them well to address the ecological demands arising from their lifestyles.[well established][VHOG] AAO:0000959 CALOHA:TS-2103 + MESH:D002319 VHOG:0001248 Wikipedia:Circulatory_system uberon @@ -31710,12 +31774,19 @@ For example, A and B may be gene products and binding of B by A positively regul ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.493 http://bgee.unil.ch/ + + + + MESH:D002319 + + https://github.com/biopragmatics/biomappings + systema cardiovasculare Wikipedia:Circulatory_system - + @@ -31796,7 +31867,7 @@ For example, A and B may be gene products and binding of B by A positively regul musculi FMA:32558 FMA:TA - + @@ -31856,6 +31927,7 @@ For example, A and B may be gene products and binding of B by A positively regul The nervous system is an organ system containing predominantly neuron and glial cells. In bilaterally symmetrical organism, it is arranged in a network of tree-like structures connected to a central body. The main functions of the nervous system are to regulate and control body functions, and to receive sensory input, process this information, and generate behavior [CUMBO]. + A regulatory system of the body that consists of neurons and neuroglial cells. The nervous system is divided into two parts, the central nervous system (CNS) and the peripheral nervous system (PNS). (Source: BioGlossary, www.Biology-Text.com)[TAO] Anatomical system consisting of nerve bodies and nerve fibers which regulate the response of the body to external and internal stimuli.[AAO] Nervous systems evolved in the ancestor of Eumetazoa.[well established][VHOG] @@ -31895,6 +31967,7 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0001016 + @@ -31952,6 +32025,12 @@ For example, A and B may be gene products and binding of B by A positively regul ISBN:978-0198566694 Schmidt-Rhaesa A, The evolution of organ systems (2007) p.117 http://bgee.unil.ch/ + + + + FBbt:00005093 + + @@ -31975,7 +32054,7 @@ For example, A and B may be gene products and binding of B by A positively regul systema nervosum Wikipedia:Nervous_system - + @@ -31997,9 +32076,10 @@ For example, A and B may be gene products and binding of B by A positively regul - + The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the neural tube derivatives: the brain and spinal cord. In invertebrates it includes central ganglia plus nerve cord. + Part of the nervous system which includes the brain and spinal cord.[AAO] The brain and spinal cord. Kimmel et al, 1995.[TAO] The central nervous system (CNS) is the part of the nervous system which includes the brain, spinal cord, and nerve cell layer of the retina (CUMBO). @@ -32039,12 +32119,13 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0001017 + central nervous system - + @@ -32058,7 +32139,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Bgee:AN @@ -32109,6 +32190,12 @@ For example, A and B may be gene products and binding of B by A positively regul ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.28 (reference 1), ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.165 (reference 2), DOI:10.1016/j.cell.2007.02.040 Denes AS, Jekely G, Steinmetz PRH, Raible F, Snyman H, Prud'homme B, Ferrier DEK, Balavoine G and Arendt D, Molecular architecture of annelid nerve cord supports common origin of nervous system centralization in Bilateria. Cell (2007) (reference 3) http://bgee.unil.ch/ + + + + FBbt:00005094 + + @@ -32128,7 +32215,7 @@ For example, A and B may be gene products and binding of B by A positively regul systema nervosum centrale FMA:55675 FMA:TA - + @@ -32220,13 +32307,19 @@ For example, A and B may be gene products and binding of B by A positively regul DOI:10.1073/pnas.97.9.4449 Shimeld SM and Holland PW. Vertebrate innovations. PNAS (2000) http://bgee.unil.ch/ + + + + FBbt:00007692 + + organa sensuum FMA:75259 FMA:TA - + @@ -32252,7 +32345,7 @@ For example, A and B may be gene products and binding of B by A positively regul organa sensuum Wikipedia:Sensory_system - + @@ -32361,6 +32454,14 @@ For example, A and B may be gene products and binding of B by A positively regul The mature structure of the neural tube exists when the tube has been segmented into the forebrain, midbrain, hindbrain and spinal cord regions. In addition neural crest has budded away from the epithelium GO:0021915 + + + + MESH:D054259 + + + https://github.com/biopragmatics/biomappings + @@ -32372,7 +32473,7 @@ For example, A and B may be gene products and binding of B by A positively regul tubus neuralis Wikipedia:Neural_tube - + @@ -32415,6 +32516,12 @@ For example, A and B may be gene products and binding of B by A positively regul FMA:62955 http://orcid.org/0000-0001-9114-8737 + + + + FBbt:10000000 + + @@ -32926,7 +33033,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Skeletal element that is composed of bone tissue. @@ -32976,14 +33083,14 @@ For example, A and B may be gene products and binding of B by A positively regul bone element - + - + VSAO-modified @@ -33094,7 +33201,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + A tube extending from the mouth to the anus. @@ -33115,6 +33222,7 @@ For example, A and B may be gene products and binding of B by A positively regul FBbt:00003125 FMA:45615 MA:0000917 + MESH:D041981 NCIT:C34082 TAO:0000112 TGMA:0001819 @@ -33136,14 +33244,14 @@ For example, A and B may be gene products and binding of B by A positively regul digestive tract - + - + NCBIBook:NBK10107 @@ -33196,6 +33304,19 @@ For example, A and B may be gene products and binding of B by A positively regul we place the MA and EMAPA class here, although the intent is probably a smaller region. See https://github.com/obophenotype/uberon/issues/509 MA + + + + FBbt:00003125 + + + + + + MESH:D041981 + + https://github.com/biopragmatics/biomappings + @@ -33474,6 +33595,12 @@ For example, A and B may be gene products and binding of B by A positively regul in FMA embryo is_a embryonic structure FMA + + + + FBbt:00004208 + + @@ -33734,7 +33861,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -33770,14 +33897,14 @@ For example, A and B may be gene products and binding of B by A positively regul musculoskeletal system - + - + check ctenophore @@ -33840,9 +33967,9 @@ For example, A and B may be gene products and binding of B by A positively regul - - - + + + @@ -33897,15 +34024,15 @@ For example, A and B may be gene products and binding of B by A positively regul notochord http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + - + - + @@ -33924,19 +34051,19 @@ For example, A and B may be gene products and binding of B by A positively regul - + http://tolweb.org/Chordata/2499 - + ZFA - + EHDAA2 @@ -34011,7 +34138,7 @@ For example, A and B may be gene products and binding of B by A positively regul notochorda Wikipedia:Notochord - + @@ -34021,8 +34148,8 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + Somites are spheres of epithelial cells that form sequentially along the anterior-posterior axis of the embryo through mesenchymal to epithelial transition of the presomitic mesoderm. EDITOR_NOTE currently classified as an epithelial vesicle, consistent with EHDAA2 and https://github.com/obophenotype/uberon/wiki/The-neural-crest. Consider making 'somitic mesoderm' a separate term and correlate with regionalization processes. Consider moving ZFA term to 'trunk somite' as it is part of the trunk @@ -34068,11 +34195,11 @@ For example, A and B may be gene products and binding of B by A positively regul somite http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + - + @@ -34085,13 +34212,13 @@ For example, A and B may be gene products and binding of B by A positively regul - + GOTAX:0000352 - + ZFA @@ -34194,7 +34321,7 @@ For example, A and B may be gene products and binding of B by A positively regul somitus Wikipedia:Somite - + @@ -34268,12 +34395,12 @@ For example, A and B may be gene products and binding of B by A positively regul - - - - + + + + A specialized region of ectoderm found between the neural ectoderm (neural plate) and non-neural ectoderm and composed of highly migratory pluripotent cells that delaminate in early embryonic development from the dorsal neural tube and give rise to an astounding variety of differentiated cell types[MP]. EDITOR_NOTE consider including subclasses for pre- and post- migratory (e.g. sheets/paths/streams). @@ -34313,66 +34440,66 @@ For example, A and B may be gene products and binding of B by A positively regul http://upload.wikimedia.org/wikipedia/commons/5/5f/Gray644.png https://upload.wikimedia.org/wikipedia/commons/8/8f/Neural_Crest.png - + - + - + - + - + - + - + XAO https://github.com/obophenotype/uberon/wiki/The-neural-crest - + Hall and others restrict NC to vertebrates but we opt for a less restrictive constraint to avoid inconsistencies when areas such as P1 area of pallium in hagfishes inherit cell lineage from telecephalon-contributing NC cells ISBN:0073040584 - + BTO - + PMID:11523831 - + pre migratory https://github.com/obophenotype/uberon/wiki/The-neural-crest - + PMID:11523831 @@ -34440,7 +34567,7 @@ For example, A and B may be gene products and binding of B by A positively regul crista neuralis Wikipedia:Neural_crest - + @@ -34513,6 +34640,12 @@ For example, A and B may be gene products and binding of B by A positively regul DOI:10.1046/j.1469-7580.2001.19910133.x Graham A. The development and evolution of the pharyngeal arches. J Anat (2001) http://bgee.unil.ch/ + + + + FBbt:00001057 + + @@ -34524,7 +34657,7 @@ For example, A and B may be gene products and binding of B by A positively regul epithelium tubi neuralis; neuroectoderma Wikipedia:Neuroectoderm - + @@ -34610,7 +34743,7 @@ For example, A and B may be gene products and binding of B by A positively regul glandula exocrina Wikipedia:Exocrine_gland - + @@ -34697,7 +34830,7 @@ For example, A and B may be gene products and binding of B by A positively regul glandulae endocrinae Wikipedia:Endocrine_gland - + @@ -34727,7 +34860,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -34785,14 +34918,14 @@ For example, A and B may be gene products and binding of B by A positively regul bone marrow http://upload.wikimedia.org/wikipedia/commons/7/74/Gray72-en.svg - + - + FMA MA @@ -34825,7 +34958,7 @@ For example, A and B may be gene products and binding of B by A positively regul medulla ossea BTO:0000141 FMA:9608 - + @@ -34833,7 +34966,7 @@ For example, A and B may be gene products and binding of B by A positively regul medulla ossium BTO:0000141 Wikipedia:Bone_marrow - + @@ -35063,14 +35196,14 @@ For example, A and B may be gene products and binding of B by A positively regul - + - + Anatomical system that is involved in the production of hematopoietic cells. @@ -35116,24 +35249,24 @@ For example, A and B may be gene products and binding of B by A positively regul hematopoietic system - + - + - + FMA - + definitional @@ -35423,6 +35556,12 @@ For example, A and B may be gene products and binding of B by A positively regul MGI:csmith MP:0002163 + + + + FBbt:00100317 + + @@ -35447,7 +35586,7 @@ For example, A and B may be gene products and binding of B by A positively regul glandula BTO:0000522 Wikipedia:Gland - + @@ -35519,7 +35658,7 @@ For example, A and B may be gene products and binding of B by A positively regul epiblastus Wikipedia:Epiblast - + @@ -35599,7 +35738,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Unsegmented field of paraxial mesoderm present posterior to the most recently formed somite pair, from which somites will form. Unsegmented field of paraxial mesoderm present posterior to the most recently formed somite pair, from which somites will form. Kimmel et al, 1995.[TAO] It is reasonable to assume that the proximate invertebrate ancestor of the vertebrates had an amphioxus-like tail bud in its larval stage. This archetypal tail bud would have (...) (3) lacked any component of mesenchyme cells, (4) budded off new mesodermal segments directly, without any intervening zone of presomitic mesoderm (...). Then, early in vertebrate evolution, epithelium-to-mesenchyme interconversions (and the gene networks for effecting them) became prominent features of development. (...) In any case, conspicuous mesenchymal components tended to be added to the vertebrate tail bud itself. In addition, a mesenchymatous presomitic mesoderm (not a part of the tail bud proper) came to intervene between the tail bud and the forming somites.[well established][VHOG] @@ -35624,14 +35763,14 @@ For example, A and B may be gene products and binding of B by A positively regul presomitic mesoderm - + - + Bgee:AN @@ -35861,9 +36000,9 @@ For example, A and B may be gene products and binding of B by A positively regul - - - + + + A region of embryonic ectodermal cells that lie directly above the notochord. During neurulation, they change shape and produce an infolding of the neural plate (the neural fold) that then seals to form the neural tube[XAO]. The earliest recognizable dorsal ectodermal primordium of the central nervous system present near the end of gastrulation before infolding to form the neural keel; consists of a thickened pseudostratified epithelium[ZFA]. The earliest recognizable dorsal ectodermal primordium of the central nervous system present near the end of gastrulation before infolding to form the neural keel; consists of a thickened pseudostratified epithelium. Kimmel et al, 1995.[TAO] (...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord that is located dorsal to the notochord (...).[well established][VHOG] @@ -35895,34 +36034,34 @@ For example, A and B may be gene products and binding of B by A positively regul neural plate https://upload.wikimedia.org/wikipedia/commons/8/8f/Neural_Crest.png - + - + - + - + GOTAX:0000352 - + Wikipedia - + Bgee:AN @@ -35953,6 +36092,14 @@ For example, A and B may be gene products and binding of B by A positively regul ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.28 http://bgee.unil.ch/ + + + + MESH:D054258 + + + https://github.com/biopragmatics/biomappings + @@ -35964,7 +36111,7 @@ For example, A and B may be gene products and binding of B by A positively regul lamina neuralis Wikipedia:Neural_plate - + @@ -35987,7 +36134,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube[GO]. Mesoderm lateral to the neural tube and notochord that is divided into cranial and post-cranial portions. The trunk portions further segment into somites.[AAO] Presently, Cephalochordata, Urochordata, and Vertebrata are placed as subphyla of the phylum Chordata, in which the overall organization of embryonic tissues (dorsal hollow nerve cord, ventral digestive tract, axial notochord, and bilateral paraxial mesoderm) is largely conserved. In contrast, the echinoderms and hemichordates are sister groups of the chordates and they lack the notochord and paraxial mesoderm. Thus, the basic mesodermal organization of vertebrates must have appeared first in the common ancestor of the chordates.[well established][VHOG] @@ -36016,7 +36163,7 @@ For example, A and B may be gene products and binding of B by A positively regul paraxial mesoderm http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + @@ -36029,7 +36176,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Bgee:AN @@ -36089,7 +36236,7 @@ For example, A and B may be gene products and binding of B by A positively regul mesoderma paraxiale Wikipedia:Paraxial_mesoderm - + @@ -36101,7 +36248,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -36145,7 +36292,7 @@ For example, A and B may be gene products and binding of B by A positively regul lateral plate mesoderm http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + @@ -36158,7 +36305,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + EHDAA2 VHOG @@ -36233,7 +36380,7 @@ For example, A and B may be gene products and binding of B by A positively regul mesoderma laminae lateralis Wikipedia:Lateral_plate_mesoderm - + @@ -36242,7 +36389,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -36285,7 +36432,7 @@ For example, A and B may be gene products and binding of B by A positively regul myotome http://upload.wikimedia.org/wikipedia/commons/9/96/Gray65.png - + @@ -36298,7 +36445,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + EHDAA2-abduced @@ -36344,7 +36491,7 @@ For example, A and B may be gene products and binding of B by A positively regul myotomus Wikipedia:Myotome - + @@ -36484,7 +36631,7 @@ For example, A and B may be gene products and binding of B by A positively regul mesenchyma Wikipedia:Mesenchyme - + @@ -36499,7 +36646,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + The part of the coelom in the embryo between the somatopleuric and splanchnopleuric mesoderm; the principal body cavities of the trunk (thoracic, abdominal, and pelvic) arise from this embryonic part of the coelom. consider merging with coelom. TODO - add spatial relationships to halves of LPM. Note the OG places XAO and ZFA coelem terms here. editor note: TODO check ZFA, which appears to be a structure present in adults (...) I regard it unlikely that coeloms of all bilaterian animals are comparable and evolved very early. Considering all these questions, few convincing characters concerning the evolution of body cavities remain to be named. (...) A segmental coelom appears to have evolved at least two times, in Annelida and in Myomerata (Acrania and Craniota).[well established][VHOG] @@ -36515,14 +36662,14 @@ For example, A and B may be gene products and binding of B by A positively regul intraembryonic coelom - + - + Wikipedia @@ -36590,6 +36737,12 @@ For example, A and B may be gene products and binding of B by A positively regul GO:0060562 PMID:12526790 + + + + FBbt:00007474 + + @@ -36850,7 +37003,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + The bilaminar epithelium formed from the myotome and dermatome. Epithelial sheet on the external surface of the somite that gives rise to trunk, muscle and dermis. Within the dermomyotome there is also a medio-lateral difference. The central region makes dermis, the mesenchymal connective tissue of the back skin. The medial region (closest to neural tube) makes epaxial muscle, and the lateral region (furthest from neural tube) makes hypaxial muscle[http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=eurekah&part=A66768]. Epithelial sheet on the external surface of the somite that gives rise to trunk, muscle and dermis.[TAO] @@ -36873,7 +37026,7 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0004290 dermomyotome - + @@ -36892,7 +37045,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + EHDAA2 ZFA @@ -37139,6 +37292,12 @@ For example, A and B may be gene products and binding of B by A positively regul We explicitly merge the NCITA terms here NCIT + + + + FBbt:00005317 + + @@ -37218,7 +37377,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + A specialized form of connective tissue in which the extracellular matrix is firm, providing the tissue with resilience, and/or mineralized and that functions in mechanical and structural support.[VSAO]. A specialized form of connective tissue in which the extracellular matrix is firm, providing the tissue with resilience, and/or mineralized and that functions in mechanical and structural support.[VSAO] EMAPA:37744 @@ -37232,7 +37391,7 @@ For example, A and B may be gene products and binding of B by A positively regul Four classes of mineralized tissues are found in vertebrates: bone, cartilage, dentine, and enamel. We think of cartilage and bone as skeletal tissues and of enamel and dentine as dental tissues, but enamel and dentine arose evolutionarily together with bone as skeletal tissues in the dermal skeleton (exoskeleton) of early vertebrates. Scales and teeth of sharks are examples of dermal skeletal elements that are still composed of the three ancient components-enamel, dentine, and bone. Cartilage, on the other hand, provided the basis for the second vertebrate skeletal system, the endoskeleton (Smith and Hall, 1990; Hall, 1998a,b). some invertebrate skeletal tissues have surprisingly bone-like features. Examples include chondrocytes interconnected by cell processes in cephalopod cartilages (Cole and Hall, 2004a,b), and the calcium phosphate layer in the shells of brachiopods (Rodland et al., 2003). However, neither bone nor mineralized cartilage have been found in invertebrates. Editors notes: TODO - develops_from skeletal tissue - + @@ -37245,7 +37404,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + 2012-08-14 VSAO:0000015 VSAO @@ -37284,7 +37443,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Organ consisting of skeletal tissue. Encompasses whole bones, fused bones, cartilaginious elements, teeth, dermal denticles. Organ entity that is typically involved in mechanical support and may have different skeletal tissue compositions at different stages.[VSAO] Organ entity that may have different tissue compositions at different stages and is typically involved in mechanical support.[TAO] @@ -37300,14 +37459,14 @@ For example, A and B may be gene products and binding of B by A positively regul skeletal element - + - + VSAO @@ -37352,7 +37511,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -37391,14 +37550,14 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0004770 articular system - + - + FMA @@ -37518,6 +37677,12 @@ For example, A and B may be gene products and binding of B by A positively regul Anatomical structure that connects two or more adjacent skeletal elements or hardened body parts. http://orcid.org/0000-0002-6601-2165 + + + + FBbt:00005811 + + @@ -37570,6 +37735,12 @@ For example, A and B may be gene products and binding of B by A positively regul A proximal-distal subdivision of the digestive tract. http://orcid.org/0000-0002-6601-2165 + + + + FBbt:00100315 + + @@ -37867,7 +38038,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Mesenchyme that is part of a developing trunk. EFO:0003485 EHDAA2:0002092 @@ -37883,14 +38054,14 @@ For example, A and B may be gene products and binding of B by A positively regul trunk mesenchyme - + - + EHDAA2 @@ -38004,6 +38175,12 @@ For example, A and B may be gene products and binding of B by A positively regul An array of photoreceptors and any supporting cells found in an eye. https://orcid.org/0000-0002-6601-2165 + + + + FBbt:00004200 + + @@ -38034,6 +38211,12 @@ For example, A and B may be gene products and binding of B by A positively regul developing anatomical structure + + + + FBbt:00007006 + + @@ -38171,7 +38354,7 @@ For example, A and B may be gene products and binding of B by A positively regul membrana basalis Wikipedia:Basement_membrane - + @@ -38189,7 +38372,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + The notochordal plate is the dorsal part of the notochordal process when the ventral portion breaks down. It is continuous laterally with the endoderm that composes the roof of the primitive foregut and is in contact dorsally with the neural tube. The folding off of the notochordal plate gives rise to the notochord. TODO - check ordering; awaiting confirmation from JB The notochordal plate is the dorsal part of the notochordal process when the ventral portion breaks down. It is continuous laterally with the endoderm that composes the roof of the primitive foregut and is in contact dorsally with the neural tube. The folding off of the notochordal plate gives rise to the notochord. [Carson_JL, Dehart_DB, Developmental_Dynamics_(1994)_201:_260-278, Gesteland_K_and_Schoenwolf_GC, Inagaki_T, Morphogenesis_of_the_murine_node_and_notochordal_plate, The_prechordal_plate, Vrablic_T, see_Mueller_F_and_O'Rahilly_R, the_rostral_end_of_the_notochord_and_nearby_median_features_in_staged_human_embryos._Cells_Tissues_Organs_(2003)_173:_1-20_and_Sulik_K][VHOG] @@ -38204,7 +38387,7 @@ For example, A and B may be gene products and binding of B by A positively regul notochordal plate - + @@ -38217,7 +38400,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + EHDAA2 @@ -38254,7 +38437,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + A midline cellular cord formed from the migration of mesenchymal cells from the primitive knot. EHDAA2:0001279 EHDAA:224 @@ -38271,14 +38454,14 @@ For example, A and B may be gene products and binding of B by A positively regul The notochordal process grows cranially until it reaches the prechordal plate, the future site of the mouth. In this area the ectoderm is attached directly to the endoderm without intervening mesoderm. This area is known as the oropharyngeal membrane, and it will break down to become the mouth. At the other end of the primitive streak the ectoderm is also fused directly to the endoderm; this is known as the cloacal membrane (proctodeum), or primordial anus. notochordal process - + - + EHDAA2 @@ -38700,7 +38883,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + A hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood or analogs[GO,modified]. note we reserve the subclass 'heart' from the vertebrate multi-chambered heart. 'The first heart-like organ is believed to have appeared 500my ago in an ancestral bilaterian'. Amniotes: four-chambered heart. Amphibians: two atria, one ventricle, pulmonary; fish: single atrium and ventricle; amphioxus: tubular, non-striated, closed, unidirectional; ascidians: tubular, striated, open, bidirectional; arthropods: tubular, open; C elegans: contractile pharynx; Cnideria: striated muscle cells associated with gastrodermis SPD:0000130 @@ -38715,14 +38898,14 @@ For example, A and B may be gene products and binding of B by A positively regul Gene notes: Bmp, Nkx, Gata primary circulatory organ - + - + GO uses blood circulation generically to include the haemolymphatic fluid of arthropods @@ -38812,7 +38995,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -38829,14 +39012,14 @@ For example, A and B may be gene products and binding of B by A positively regul presumptive segmental plate - + - + https://github.com/obophenotype/uberon/wiki/The-neural-crest EDHAA2 @@ -38935,7 +39118,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -38961,7 +39144,7 @@ For example, A and B may be gene products and binding of B by A positively regul presumptive paraxial mesoderm - + @@ -38977,7 +39160,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + https://github.com/obophenotype/uberon/issues/1277 @@ -39026,7 +39209,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Mesenchyme with little extracellular matrix. AEO:0000146 EHDAA2:0003146 @@ -39034,7 +39217,7 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0007524 dense mesenchyme tissue - + @@ -39047,7 +39230,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + AEO @@ -39226,7 +39409,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -39243,14 +39426,14 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0009142 entire embryonic mesenchyme - + - + EHDAA2 @@ -39272,7 +39455,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + EHDAA2:0002094 trunk and cervical paraxial mesenchyme uberon @@ -39280,14 +39463,14 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0009618 trunk paraxial mesoderm - + - + EHDAA2 @@ -39351,6 +39534,12 @@ For example, A and B may be gene products and binding of B by A positively regul An anatomical structure that has more than one cell as a part. CARO:0010000 + + + + FBbt:00100313 + + @@ -39489,12 +39678,14 @@ For example, A and B may be gene products and binding of B by A positively regul + FBbt:00007330 FMA:67509 SCTID:91690000 uberon UBERON:0011216 + organ system subdivision @@ -39510,6 +39701,12 @@ For example, A and B may be gene products and binding of B by A positively regul A subdivision of an anatomical system. http://orcid.org/0000-0002-6601-2165 + + + + FBbt:00007330 + + @@ -39743,7 +39940,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -39768,7 +39965,7 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0011899 epimysium - + @@ -39781,7 +39978,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + FMA @@ -39887,7 +40084,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -39909,7 +40106,7 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0012429 hematopoietic tissue - + @@ -39922,7 +40119,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + defitional @@ -40085,7 +40282,6 @@ For example, A and B may be gene products and binding of B by A positively regul The region of the organism associated with the visceral organs. - Cardinal body part, which consists of a maximal set of diverse subclasses of organ and organ part spatially associated with the vertebral column and ribcage. Examples: There is only one body proper[FMA:231424]. AEO:0000103 BTO:0001489 @@ -40095,7 +40291,6 @@ For example, A and B may be gene products and binding of B by A positively regul body whole body UBERON:0013702 - body proper @@ -40196,6 +40391,7 @@ For example, A and B may be gene products and binding of B by A positively regul A muscle organ that consists of skeletal muscle tissue ensheathed in epimysium, that develops from myotome and that is innervated by some somatic motor neuron. Skeletal muscles are typically attached (via a tendon) to a bone but there are exceptions (e.g. intrinsic tongue muscles). + skeletal muscle AAO:0011099 BTO:0001103 @@ -40218,6 +40414,7 @@ For example, A and B may be gene products and binding of B by A positively regul ZFA:0005277 uberon UBERON:0014892 + skeletal muscle organ, vertebrate @@ -40249,6 +40446,12 @@ For example, A and B may be gene products and binding of B by A positively regul FBC:DOS FBbt:00007278 + + + + FBbt:00007278 + + @@ -40498,7 +40701,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -40521,7 +40724,7 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0016887 entire extraembryonic component - + @@ -40534,7 +40737,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + AEO @@ -40620,7 +40823,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -40628,22 +40831,24 @@ For example, A and B may be gene products and binding of B by A positively regul Added for consistency with MA EMAPA and EHDAA2. See https://github.com/obophenotype/mouse-anatomy-ontology/issues/104 + EHDAA2:0001842 EMAPA:35578 MA:0000165 uberon UBERON:0018254 + skeletal musculature - + - + MA @@ -40756,6 +40961,12 @@ For example, A and B may be gene products and binding of B by A positively regul Material anatomical entity consisting of multiple anatomical structures that are not connected to each other. CARO:0020000 + + + + FBbt:00007276 + + @@ -41184,6 +41395,24 @@ For example, A and B may be gene products and binding of B by A positively regul + + + + + + + + + + + + + + + + + + @@ -41204,6 +41433,16 @@ For example, A and B may be gene products and binding of B by A positively regul + + + + + + + + + + diff --git a/src/ontology/subsets/general_cell_types_upper_slim.tsv b/src/ontology/subsets/general_cell_types_upper_slim.tsv index 75c36b0e2..a0a6dd677 100644 --- a/src/ontology/subsets/general_cell_types_upper_slim.tsv +++ b/src/ontology/subsets/general_cell_types_upper_slim.tsv @@ -1,278 +1,275 @@ ?x ?label -_:B29fb0e95X2D184aX2D4ac6X2D9e6aX2Dbd864e34a507genid1001 -_:B29fb0e95X2D184aX2D4ac6X2D9e6aX2Dbd864e34a507genid1050 -_:B29fb0e95X2D184aX2D4ac6X2D9e6aX2Dbd864e34a507genid1057 -_:B29fb0e95X2D184aX2D4ac6X2D9e6aX2Dbd864e34a507genid1064 -_:B29fb0e95X2D184aX2D4ac6X2D9e6aX2Dbd864e34a507genid1074 -_:B29fb0e95X2D184aX2D4ac6X2D9e6aX2Dbd864e34a507genid1081 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+_:B9ac295d7X2Ded0bX2D4368X2D889cX2D7714613be411genid873 +_:B9ac295d7X2Ded0bX2D4368X2D889cX2D7714613be411genid879 +_:B9ac295d7X2Ded0bX2D4368X2D889cX2D7714613be411genid888 +_:B9ac295d7X2Ded0bX2D4368X2D889cX2D7714613be411genid900 +_:B9ac295d7X2Ded0bX2D4368X2D889cX2D7714613be411genid915 +_:B9ac295d7X2Ded0bX2D4368X2D889cX2D7714613be411genid922 +_:B9ac295d7X2Ded0bX2D4368X2D889cX2D7714613be411genid928 +_:B9ac295d7X2Ded0bX2D4368X2D889cX2D7714613be411genid938 +_:B9ac295d7X2Ded0bX2D4368X2D889cX2D7714613be411genid948 +_:B9ac295d7X2Ded0bX2D4368X2D889cX2D7714613be411genid974 +_:B9ac295d7X2Ded0bX2D4368X2D889cX2D7714613be411genid990 +_:B9ac295d7X2Ded0bX2D4368X2D889cX2D7714613be411genid998 "continuant" "occurrent" "independent continuant" @@ -409,7 +406,6 @@ _:B29fb0e95X2D184aX2D4ac6X2D9e6aX2Dbd864e34a507genid993 "precursor cell" "neutrophillic cytoplasm" "basophilic cytoplasm" - "increased nucleus size" "bone marrow hematopoietic cell" "reproduction" "lytic vacuole" @@ -688,6 +684,7 @@ _:B29fb0e95X2D184aX2D4ac6X2D9e6aX2Dbd864e34a507genid993 "plasma membrane bounded cell projection organization" "exocytic process" "export from cell" + "defense response to symbiont" "organic substance biosynthetic process" "regulation of leukocyte differentiation" "mononuclear cell differentiation" @@ -728,13 +725,8 @@ _:B29fb0e95X2D184aX2D4ac6X2D9e6aX2Dbd864e34a507genid993 "quality" "morphology" "shape" - "qualitative" - "deviation (from_normal)" - "size" "structure" "circular" - "normal" - "increased size" "elliptic" "physical quality" "physical object quality" @@ -762,14 +754,13 @@ _:B29fb0e95X2D184aX2D4ac6X2D9e6aX2Dbd864e34a507genid993 "subcylindrical" "3-D shape" "tubular" - "increased quality" - "increased object quality" "fiber shaped" "superelliptic" "transversely striated" "nucleated" "disconnected" "polymeric" + "high nuclear/cytoplasmic ratio" "anatomical structure quality" "anatomical histological quality" "neutrophillic" diff --git a/src/ontology/subsets/kidney_upper_slim.json b/src/ontology/subsets/kidney_upper_slim.json index f1316cf80..84c2067cc 100644 --- a/src/ontology/subsets/kidney_upper_slim.json +++ b/src/ontology/subsets/kidney_upper_slim.json @@ -4,9 +4,9 @@ "meta" : { "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2002/07/owl#versionInfo", - "val" : "2024-01-04" + "val" : "2024-02-13" } ], - "version" : "http://purl.obolibrary.org/obo/cl/releases/2024-01-04/subsets/kidney_upper_slim.owl" + "version" : "http://purl.obolibrary.org/obo/cl/releases/2024-02-13/subsets/kidney_upper_slim.owl" }, "nodes" : [ { "id" : "http://purl.obolibrary.org/obo/BFO_0000002", @@ -731,7 +731,7 @@ "xrefs" : [ "CARO:mah" ] }, "comments" : [ "The definition of cell is intended to represent all cells, and thus a cell is defined as a material entity and not an anatomical structure, which implies that it is part of an organism (or the entirety of one)." ], - "subsets" : [ "http://purl.obolibrary.org/obo/ubprop#_upper_level" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/ubprop#_upper_level" ], "xrefs" : [ { "val" : "CALOHA:TS-2035" }, { @@ -772,7 +772,7 @@ "xrefs" : [ "GOC:tfm", "MESH:D013234" ] }, "comments" : [ "This term applies to metazoan. For plant stem cells, consider using PO:0004011 ‘initial cell’ or its parent PO:0004010 ‘meristematic cell’." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "animal stem cell" @@ -797,7 +797,7 @@ "xrefs" : [ "GOC:add", "GOC:dsd", "GOC:tfm", "PMID:19022770", "http://en.wikipedia.org/wiki/Hematopoietic_stem_cell" ] }, "comments" : [ "Markers differ between species, and two sets of markers have been described for mice. HSCs are reportedly CD34-positive, CD45-positive, CD48-negative, CD150-positive, CD133-positive, and CD244-negative." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "blood forming stem cell" @@ -837,7 +837,7 @@ "val" : "A progenitor cell committed to the erythroid lineage.", "xrefs" : [ "GOC:add", "ISBN:0721601464" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003000", "pred" : "hasRelatedSynonym", @@ -911,7 +911,7 @@ "xrefs" : [ "GOC:add", "ISBN:0878932437", "MESH:D023461" ] }, "comments" : [ "This cell type is intended to be compatible with any vertebrate common myeloid progenitor. For mammalian CMP known to be CD34-positive, please use the term 'common myeloid progenitor, CD34-positive' (CL_0001059)." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "common myeloid precursor" @@ -965,7 +965,7 @@ "xrefs" : [ "GOC:add", "GOC:dsd", "GOC:tfm", "MESH:D055015", "PMID:16647566", "http://en.wikipedia.org/wiki/Megakaryocyte-erythroid_progenitor_cell" ] }, "comments" : [ "MEPs are reportedly CD19-negative, CD34-negative, CD45RA-negative, CD110-positive, CD117-positive, and SCA1-negative and reportedly express the transcription factors GATA-1 and NF-E2." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "CFU-EM" @@ -1022,6 +1022,7 @@ "xrefs" : [ "SANBI:mhl" ] }, "comments" : [ "define using PATO mulit-potent or oligopotent?" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "blast cell" @@ -1063,7 +1064,7 @@ "xrefs" : [ "ISBN:0517223651", "MESH:D005347", "http://en.wikipedia.org/wiki/Fibroblast" ] }, "comments" : [ "These cells may be vimentin-positive, fibronectin-positive, fsp1-positive, MMP-1-positive, collagen I-positive, collagen III-positive, and alpha-SMA-negative." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { "val" : "BTO:0000452" }, { @@ -1089,6 +1090,7 @@ "val" : "A cell that has a filiform extrusion of the cell surface.", "xrefs" : [ "GOC:tfm" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "VHOG:0001532" }, { @@ -1104,7 +1106,7 @@ "val" : "A cell that is usually found in a two-dimensional sheet with a free surface. The cell has a cytoskeleton that allows for tight cell to cell contact and for cell polarity where apical part is directed towards the lumen and the basal part to the basal lamina.", "xrefs" : [ "FB:ma", "GOC:tfm", "MESH:D004847" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "epitheliocyte" @@ -1139,6 +1141,7 @@ "val" : "An epithelial cell that has a cilia.", "xrefs" : [ "GOC:tfm" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "FMA:70605" } ] @@ -1151,7 +1154,8 @@ "definition" : { "val" : "An epithelial cell that is part of a duct.", "xrefs" : [ "https://orcid.org/0000-0001-5208-3432" ] - } + }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000071", @@ -1162,7 +1166,7 @@ "val" : "An endothelial cell that lines the vasculature.", "xrefs" : [ "GOC:tfm" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cuboidal endothelial cell of vascular tree" @@ -1185,7 +1189,7 @@ "val" : "A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube.", "xrefs" : [ "GO:0002065", "https://orcid.org/0000-0001-5208-3432" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" @@ -1196,6 +1200,7 @@ "lbl" : "squamous epithelial cell", "type" : "CLASS", "meta" : { + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "CALOHA:TS-1249" } ] @@ -1209,7 +1214,7 @@ "val" : "A cell found predominately in the blood.", "xrefs" : [ "GOC:add", "GOC:tfm" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim" ], "xrefs" : [ { "val" : "FMA:62844" }, { @@ -1226,7 +1231,7 @@ "xrefs" : [ "GOC:tfm", "MESH:D042783", "PMID:21275341", "http://en.wikipedia.org/wiki/Endothelial_cell", "https://sourceforge.net/tracker/?func=detail&atid=440764&aid=3364936&group_id=36855" ] }, "comments" : [ "From FMA: 9.07.2001: Endothelial cell has always been classified as a kind of epithelial cell, specifically a squamous cell but that is not true. First, endothelial cell can either be squamous or cuboidal (e.g. high-endothelial cell) and secondly, it has different embryological derivation (mesodermal) than a true epithelial cell (ectodermal and endodermal). The basis for present classification is the fact that it comprises the outermost layer or lining of anatomical structures (location-based) but a better structural basis for the differentia is the cytoskeleton of the cell. Endothelial cell has vimentin filaments while an epithelial cell has keratin filaments. [Onard]." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "endotheliocyte" @@ -1267,6 +1272,7 @@ "xrefs" : [ "FB:ma", "GOC:dsd", "PMCID:PMC2613570", "PMID:10102814", "PMID:16923606", "PMID:17986482", "PMID:19960544", "http://en.wikipedia.org/wiki/Mesenchymal_stem_cell", "http://www.copewithcytokines.de/cope.cgi?key=mesenchymal%20stem%20cells" ] }, "comments" : [ "Many but not all mesenchymal cells derive from the mesoderm. MSCs are reportedly CD3-negative, CD4-negative, CD5-negative, CD8-negative, CD11a-negative, CD11b-negative, CD14-negative, CD19-negative, CD29-positive, CD31-negative, CD34-negative, CD38-negative, CD40-negative, CD44-positive, CD45-negative, CD49-positive, CD54-positive, CD66b-negative, CD79a-negative, CD80-negative, CD102-positive, CD106-positive, CD117-positive, CD121a-positive, CD121b-positive, CD123-positive, CD124-positive, CD133-negative, CD146-positive, CD166-positive, CD271-positive, B220-negative, Gr1-negative, MHCI-positive, MHCII-negative, SSEA4-negative, sca1-positive, Ter119-negative, and glycophorin A-negative. Cultured MSCs are capable of producing stem cell factor, IL7, IL8, IL11, TGF-beta, cofilin, galectin-1, laminin-receptor 1, cyclophilin A, and MMP-2." ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "bone marrow stromal cells" @@ -1335,6 +1341,7 @@ "val" : "A cell that specializes in controlled release of one or more substances.", "xrefs" : [ "GOC:tfm", "ISBN:0721662544" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "BTO:0003659" }, { @@ -1353,7 +1360,8 @@ "definition" : { "val" : "A cell whose primary function is to shorten.", "xrefs" : [ "FB:ma" ] - } + }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000187", @@ -1364,6 +1372,7 @@ "val" : "A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns.", "xrefs" : [ "MESH:D032342" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "muscle fiber" @@ -1398,7 +1407,7 @@ "val" : "A non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels. They develop from specialized myoblasts (smooth muscle myoblast).", "xrefs" : [ "MESH:D032389", "PMID:9315361", "http://en.wikipedia.org/wiki/Smooth_muscle_cell" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "non-striated muscle cell" @@ -1496,6 +1505,7 @@ "val" : "A cell of the middle germ layer of the embryo.", "xrefs" : [ "MESH:D008648" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "mesoblast" @@ -1533,7 +1543,7 @@ "val" : "A red blood cell. In mammals, mature erythrocytes are biconcave disks containing hemoglobin whose function is to transport oxygen.", "xrefs" : [ "GOC:tfm", "MESH:D004912" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "RBC" @@ -1562,6 +1572,7 @@ "lbl" : "eukaryotic cell", "type" : "CLASS", "meta" : { + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "MESH:D005057" } ] @@ -1653,6 +1664,7 @@ "val" : "A precursor cell destined to differentiate into smooth muscle myocytes.", "xrefs" : [ "GOC:tfm", "MESH:D032390" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "myoblast, smooth muscle", @@ -1675,7 +1687,7 @@ "xrefs" : [ "MESH:D009474", "http://en.wikipedia.org/wiki/Neuron" ] }, "comments" : [ "These cells are also reportedly CD4-negative and CD200-positive. They are also capable of producing CD40L and IFN-gamma." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "nerve cell" @@ -1710,7 +1722,7 @@ "val" : "An immature, nucleated erythrocyte occupying the stage of erythropoeisis that follows formation of erythroid progenitor cells. This cell is CD71-positive, has both a nucleus and a nucleolus, and lacks hematopoeitic lineage markers.", "xrefs" : [ "ISBN:0721601464", "PMID:1638021" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "rubriblast", @@ -1834,7 +1846,7 @@ "xrefs" : [ "GOC:dsd", "GOC:tfm", "ISBN:0721601464" ] }, "comments" : [ "Lineage negative is described here as CD2-negative, CD3-negative, CD4-negative, CD5-negative, CD8a-negative, CD14-negative, CD19-negative, CD20-negative, CD56-negative, Ly6g-negative, and Ter119-negative." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "CFU-Meg", @@ -1894,7 +1906,7 @@ "xrefs" : [ "ISBN:0721601464", "MESH:D008533", "PMID:31043076", "http://en.wikipedia.org/wiki/Megakaryocyte" ] }, "comments" : [ "Megakaryocytes are reportedly CD181-positive and CD182-positive." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "megacaryocyte" @@ -1926,7 +1938,7 @@ "val" : "An immature erythrocyte that changes the protein composition of its plasma membrane by exosome formation and extrusion. The types of protein removed differ between species though removal of the transferrin receptor is apparent in mammals and birds.", "xrefs" : [ "GOC:add", "GOC:tfm", "PMID:15946868", "PMID:2037622" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "BTO:0001173" }, { @@ -1962,6 +1974,7 @@ "val" : "The reproductive cell in multicellular organisms.", "xrefs" : [ "MESH:D005854" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "BTO:0000535" }, { @@ -1981,6 +1994,7 @@ "val" : "A cell whose primary function is to support other cell types.", "xrefs" : [ "FB:ma", "GOC:tfm" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "supportive cell" @@ -2027,6 +2041,7 @@ "xrefs" : [ "GOC:tfm", "http://www.copewithcytokines.de/cope.cgi?key=mesangial%20cells" ] }, "comments" : [ "Do all of these cells really develop from some mesenchymal stem cell?" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "kidney mesangial cell" @@ -2046,6 +2061,7 @@ "lbl" : "fenestrated cell", "type" : "CLASS", "meta" : { + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "window cell" @@ -2061,7 +2077,7 @@ "xrefs" : [ "GOC:dsd", "GOC:tfm", "ISBN:0721662544", "MESH:D020286", "PMID:16807374", "PMID:17986482", "PMID:20024907" ] }, "comments" : [ "Pericytes are CD10-positive, CD13-positive, CD31-negative, CD45-negative, CD106-positive, CD117-negative, CD140-positive, CD144-negative, CD146-positive, CD271-positive, CD325-positive, NG2-positive, RGS5-positive, SMA-positive, and desmin-positive. A subpopulation is CD248-positive. They are also capable of producing angiopoietin 1, CXCL12, TGF-beta, and VEGF-A." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "ARC", @@ -2100,7 +2116,8 @@ "definition" : { "val" : "A non-terminally differentiated cell that is capable of developing into a muscle cell.", "xrefs" : [ "GOC:add" ] - } + }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000723", @@ -2126,6 +2143,7 @@ "val" : "A cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage.", "xrefs" : [ "GOC:add" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "BTO:0001441" }, { @@ -2144,7 +2162,7 @@ "xrefs" : [ "GOC:add", "GOC:tfm" ] }, "comments" : [ "Note that in FMA erythropoietic cells are types of nucleated erythrocytes and thus don't include erythrocytes." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "erythropoietic cell" @@ -2170,7 +2188,7 @@ "val" : "A nucleated precursor of an erythrocyte that lacks hematopoietic lineage markers.", "xrefs" : [ "GOC:add", "ISBN:0721601464", "PMID:18174176" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "normoblast" @@ -2195,7 +2213,7 @@ "xrefs" : [ "GOC:add", "GOC:tfm", "PMID:19022770" ] }, "comments" : [ "Markers differ between mouse and human." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "MPP" @@ -2223,7 +2241,7 @@ "xrefs" : [ "GOC:add", "GOC:tfm", "PMID:19022770" ] }, "comments" : [ "Note that this is a class of cell types, not an identified single cell type." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "myeloid progenitor cell" @@ -2249,6 +2267,7 @@ "val" : "A cell of a hematopoietic lineage.", "xrefs" : [ "GOC:add", "GO_REF:0000031" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "haematopoietic cell" @@ -2360,6 +2379,7 @@ "xrefs" : [ "GOC:dsd", "GOC:tfm", "PMID:12768659" ] }, "comments" : [ "These cells are reportedly CD31-positive, CD34-positive, CD144-positive, TAL1-positive." ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "vascular endothelial cell" @@ -2423,7 +2443,7 @@ "val" : "An endothelial cell found in the glomerulus of the kidney. This cell is flattened, highly fenestrated, and plays a vital role in the formation of glomerular ultrafiltrate.", "xrefs" : [ "GOC:tfm", "PMID:15840009" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#kidney_upper_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#kidney_upper_slim" ], "xrefs" : [ { "val" : "BTO:0004632" }, { @@ -2486,7 +2506,7 @@ "val" : "An epithelial cell of the proximal tubule of the kidney.", "xrefs" : [ "GOC:tfm", "ISBN:1-4160-2328-3" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#kidney_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#kidney_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "kidney proximal tubule epithelial cell" @@ -2510,6 +2530,7 @@ "val" : "A cell that is part of the nervous system.", "xrefs" : [ "GOC:tfm", "ISBN:0618947256" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "CALOHA:TS-2040" }, { @@ -2532,6 +2553,7 @@ "val" : "A cell of the supporting or framework tissue of the body, arising chiefly from the embryonic mesoderm and including adipose tissue, cartilage, and bone.", "xrefs" : [ "GOC:tfm", "ISBN:0618947256" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "CALOHA:TS-2096" }, { @@ -2611,6 +2633,7 @@ "val" : "An epithelial cell of the kidney.", "xrefs" : [ "GOC:tfm", "KUPO:SJ" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "KUPO:0001019" } ], @@ -2677,7 +2700,8 @@ "definition" : { "val" : "A cuboidal epithelial cell of the kidney which regulates sodium and potassium balance. The activity of sodium and potassium channels on the apical membrane of the cell is regulated by aldosterone and vasopressin. In mammals this cell type is located in the renal collecting duct system.", "xrefs" : [ "CL:CVS" ] - } + }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0007004", @@ -2714,7 +2738,8 @@ "definition" : { "val" : "Any hematopoietic cell that is a precursor of some other hematopoietic cell type.", "xrefs" : [ "GOC:dos" ] - } + }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0008007", @@ -2737,7 +2762,7 @@ "definition" : { "val" : "A non-polarised cell precursor cell that is part of some mesenchyme, is associated with the cell matrix but is not connected to other cells and is capable of migration." }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "mesenchyme cell" @@ -2756,7 +2781,7 @@ "val" : "Mural cells are pericytes and the vascular smooth muscle cells (vSMCs) of the microcirculation.", "xrefs" : [ "Wiki:Mural_cell&oldid=930603194" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#added_for_HCA", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#added_for_HCA", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" @@ -2792,7 +2817,8 @@ "definition" : { "val" : "A cell of the neural crest. Neural crest cells are multipotent. Premigratory neural crest cells are found at the neural plate boarder, some of which will undergo ectomesynchymal transition and delamination to form migratory neural crest cells.", "xrefs" : [ "https://orcid.org/0000-0001-5208-3432", "https://orcid.org/0000-0002-9900-7880" ] - } + }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0011026", @@ -2803,6 +2829,7 @@ "val" : "A precursor cell that has a tendency to differentiate into a specific type of cell. They are descendants of stem cells, only they are more constrained in their differentiation potential or capacity for self-renewal, and are often more limited in both senses.", "xrefs" : [ "ISBN:978-1-62808-994-3", "https://doi.org/10.1016/B978-0-12-409503-8.00002-0" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0001-5208-3432" @@ -2817,7 +2844,8 @@ "val" : "A cell that, by division or terminal differentiation, can give rise to other cell types.", "xrefs" : [ "GOC:dos" ] }, - "comments" : [ "Work is needed on GO 'cell differentiation' before it is clear whether the equivalent class definition 'native cell' that capable_of some 'cell differentiation' works. Also, may want to consider merging this with non-terminally differentiated cell." ] + "comments" : [ "Work is needed on GO 'cell differentiation' before it is clear whether the equivalent class definition 'native cell' that capable_of some 'cell differentiation' works. Also, may want to consider merging this with non-terminally differentiated cell." ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0017502", @@ -2874,23 +2902,6 @@ "val" : "2009-12-28T04:25:23Z" } ] } - }, { - "id" : "http://purl.obolibrary.org/obo/CL_0017505", - "lbl" : "increased nucleus size", - "type" : "CLASS", - "meta" : { - "definition" : { - "val" : "A nucleus size quality which is relatively high compared to the amount of cytoplasm present in the same cell.", - "xrefs" : [ "GOC:tfm" ] - }, - "basicPropertyValues" : [ { - "pred" : "http://purl.org/dc/terms/contributor", - "val" : "https://orcid.org/0000-0003-1980-3228" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", - "val" : "2009-12-23T10:53:24Z" - } ] - } }, { "id" : "http://purl.obolibrary.org/obo/CL_1000449", "lbl" : "epithelial cell of nephron", @@ -2900,6 +2911,7 @@ "val" : "An epithelial cell that is part of the nephron.", "xrefs" : [ "GOC:tfm" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "FMA:70965" } ] @@ -2913,7 +2925,7 @@ "val" : "An epithelial cell that is part of the glomerular capsule.", "xrefs" : [ "GOC:tfm" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#kidney_upper_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#kidney_upper_slim" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "Bowmans capsule epithelial cell" @@ -2937,7 +2949,7 @@ "val" : "An epithelial cell that is part of the collecting duct of renal tubule.", "xrefs" : [ "GOC:tfm" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#kidney_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#kidney_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "epithelial cell of renal collecting tubule", @@ -2963,6 +2975,7 @@ "xrefs" : [ "GOC:tfm" ] }, "comments" : [ "This needs to be further defined as a juxtamedullary nephron. Will request the juxtamedullary nephron tubule class from UBERON." ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "kidney tubule epithelial cell" @@ -2981,6 +2994,7 @@ "definition" : { "val" : "A cell that is part of a kidney." }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "KUPO:0001010" } ] @@ -2993,7 +3007,7 @@ "definition" : { "val" : "A cell that is part of kidney interstitium." }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#kidney_upper_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#kidney_upper_slim" ], "xrefs" : [ { "val" : "KUPO:0001013" } ] @@ -3041,6 +3055,7 @@ "lbl" : "kidney glomerular epithelial cell", "type" : "CLASS", "meta" : { + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "KUPO:0001023" } ] @@ -3083,6 +3098,7 @@ "lbl" : "kidney cortex tubule cell", "type" : "CLASS", "meta" : { + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "KUPO:0001024" } ] @@ -3107,7 +3123,7 @@ "lbl" : "kidney interstitial fibroblast", "type" : "CLASS", "meta" : { - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { "val" : "KUPO:0001102" } ], @@ -3130,7 +3146,7 @@ "lbl" : "kidney connecting tubule epithelial cell", "type" : "CLASS", "meta" : { - "subsets" : [ "http://purl.obolibrary.org/obo/cl#kidney_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#kidney_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { "val" : "KUPO:0001058" } ], @@ -3144,7 +3160,7 @@ "lbl" : "kidney distal convoluted tubule epithelial cell", "type" : "CLASS", "meta" : { - "subsets" : [ "http://purl.obolibrary.org/obo/cl#kidney_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#kidney_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { "val" : "KUPO:0001056" } ], @@ -3177,7 +3193,7 @@ "lbl" : "kidney capillary endothelial cell", "type" : "CLASS", "meta" : { - "subsets" : [ "http://purl.obolibrary.org/obo/cl#kidney_upper_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#kidney_upper_slim" ], "xrefs" : [ { "val" : "KUPO:0001030" } ] @@ -3197,6 +3213,7 @@ "lbl" : "kidney loop of Henle epithelial cell", "type" : "CLASS", "meta" : { + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "KUPO:0001047" } ] @@ -3206,7 +3223,7 @@ "lbl" : "kidney loop of Henle ascending limb epithelial cell", "type" : "CLASS", "meta" : { - "subsets" : [ "http://purl.obolibrary.org/obo/cl#kidney_upper_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#kidney_upper_slim" ], "xrefs" : [ { "val" : "KUPO:0001048" } ] @@ -3229,6 +3246,7 @@ "definition" : { "val" : "A cell that is part of a collecting duct of renal tubule." }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "KUPO:0001012" }, { @@ -3243,7 +3261,7 @@ "definition" : { "val" : "A pericyte cell located in the kidney interstitium." }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { "val" : "KUPO:0001104" } ], @@ -4099,7 +4117,7 @@ "type" : "CLASS", "meta" : { "definition" : { - "val" : "A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex).", + "val" : "A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex).", "xrefs" : [ "GOC:pdt" ] }, "comments" : [ "Note that, in addition to forming the root of the cellular component ontology, this term is recommended for the annotation of gene products whose cellular component is unknown. When this term is used for annotation, it indicates that no information was available about the cellular component of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this." ], @@ -4139,7 +4157,7 @@ "xrefs" : [ "GOC:go_curators" ] }, "comments" : [ "Note that this term is intended to annotate gene products that are not attached to the cell surface. For gene products from multicellular organisms which are secreted from a cell but retained within the organism (i.e. released into the interstitial fluid or blood), consider the cellular component term 'extracellular space ; GO:0005615'." ], - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_yeast", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "extracellular" @@ -4257,7 +4275,7 @@ "xrefs" : [ "ISBN:0198547684" ] }, "comments" : [ "Note that for multicellular organisms, the extracellular space refers to everything outside a cell, but still within the organism (excluding the extracellular matrix). Gene products from a multi-cellular organism that are secreted from a cell into the interstitial fluid or blood can therefore be annotated to this term." ], - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "intercellular space" @@ -4347,7 +4365,7 @@ "xrefs" : [ "ISBN:0198547684" ] }, "comments" : [ "Chromosomes include parts that are not part of the chromatin. Examples include the kinetochore." ], - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_yeast", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "interphase chromosome" @@ -4395,7 +4413,7 @@ "val" : "The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.", "xrefs" : [ "ISBN:0198547684" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_yeast", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "xrefs" : [ { "val" : "Wikipedia:Cytoplasm" } ], @@ -4495,7 +4513,7 @@ "val" : "An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins.", "xrefs" : [ "ISBN:0198506732" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_yeast", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "free ribosome", @@ -4530,7 +4548,7 @@ "val" : "A cellular structure that forms the internal framework of eukaryotic and prokaryotic cells. The cytoskeleton includes intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.", "xrefs" : [ "GOC:mah", "PMID:16959967", "PMID:27419875" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_yeast", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "xrefs" : [ { "val" : "Wikipedia:Cytoskeleton" } ], @@ -4579,7 +4597,7 @@ "val" : "The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.", "xrefs" : [ "ISBN:0716731363" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_yeast", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "juxtamembrane" @@ -4764,7 +4782,7 @@ "val" : "The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.", "xrefs" : [ "GOC:go_curators" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "protein anabolism" @@ -4903,7 +4921,7 @@ "xrefs" : [ "GOC:dos", "GOC:dph", "GOC:jl", "GOC:mah" ] }, "comments" : [ "Note that this term should not be used for direct annotation. It should be possible to make a more specific annotation to one of the children of this term, for e.g. to transmembrane transport, to microtubule-based transport or to vesicle-mediated transport." ], - "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "single-organism transport" @@ -5148,7 +5166,7 @@ "val" : "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures.", "xrefs" : [ "GOC:dph", "GOC:jl", "GOC:mah" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_yeast", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cytoskeleton organisation" @@ -5742,7 +5760,7 @@ "val" : "Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538).", "xrefs" : [ "GOC:mah", "GOC:mtg_apoptosis", "PMID:25236395" ] }, - "comments" : [ "This term should not be used for direct annotation, it is currently kept in GO as a placeholder for describing cell death phenotypes in uPHENO. When information is provided on a programmed cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'). Unintentional cell death, i.e. cell death caused by injury, ageing, or cell phenotypes observed as a result of a pathological mutation in an essential gene should NOT be annotated using GO terms." ], + "comments" : [ "This term should not be used for direct annotation, it is currently kept in GO as a placeholder for describing cell death phenotypes in uPHENO. When information is provided on a programmed cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'). Unintentional cell death, i.e. cell death caused by injury, ageing, or cell phenotypes observed as a result of a pathological mutation in an essential gene should NOT be annotated using GO terms." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", @@ -6142,7 +6160,7 @@ "xrefs" : [ "GOC:lr", "GOC:mtg_apoptosis" ] }, "comments" : [ "Note that this term should be used to annotate gene products in the organism undergoing the programmed cell death. To annotate genes in another organism whose products modulate programmed cell death in a host organism, consider the term 'modulation by symbiont of host programmed cell death ; GO:0052040'. Also, note that 'programmed cell death ; GO:0012501' should be used to refer to instances of caspase-independent cell death mechanisms, in the absence of further indications on the process taking place. At present, caspase-independent cell death is not yet represented in GO due to the lack of consensus and in-depth research on the topic. 'programmed cell death ; GO:0012501' may also be used to annotate gene products in taxa where apoptosis as defined in GO:0006915 does not occur, such as plants. You may also consider these specific children: GO:0097468 'programmed cell death in response to reactive oxygen species' (with descendants GO:0010421 'hydrogen peroxide-mediated programmed cell death' and GO:0010343 'singlet oxygen-mediated programmed cell death'), and GO:0009626 'plant-type hypersensitive response' and its children." ], - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "regulated cell death" @@ -6760,7 +6778,7 @@ "xrefs" : [ "GOC:mtg_signal", "GOC:mtg_signaling_feb11", "GOC:signaling" ] }, "comments" : [ "Note that a signal is any variable property or parameter that serves to convey information, and may be a physical entity such as a gene product or small molecule, a photon, or a change in state such as movement or voltage change." ], - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pombe", "http://purl.obolibrary.org/obo/go#goslim_yeast", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pombe", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "biological signaling" @@ -6826,7 +6844,7 @@ "val" : "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon.", "xrefs" : [ "GOC:jl", "GOC:mah", "http://www.cogsci.princeton.edu/~wn/" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cell projection organisation" @@ -7144,7 +7162,7 @@ "val" : "A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues.", "xrefs" : [ "GOC:BHF", "GOC:mah", "GOC:rph", "NIF_Subcellular:nlx_subcell_20090513", "PMID:21123617", "PMID:28089324" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "proteinaceous extracellular matrix" @@ -8025,7 +8043,7 @@ "val" : "A prolongation or process extending from a cell, e.g. a flagellum or axon.", "xrefs" : [ "GOC:jl", "http://www.cogsci.princeton.edu/~wn/" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "cell process" @@ -8082,7 +8100,7 @@ "val" : "The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.", "xrefs" : [ "GOC:mah" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_pir" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_pir" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "biopolymer metabolic process", @@ -8098,6 +8116,9 @@ "val" : "multicellular organismal macromolecule metabolic process" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/26424" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0034960" }, { @@ -8120,7 +8141,7 @@ "val" : "Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane.", "xrefs" : [ "GOC:go_curators" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "xrefs" : [ { "val" : "NIF_Subcellular:sao1539965131" }, { @@ -8420,12 +8441,15 @@ "val" : "The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.", "xrefs" : [ "GOC:go_curators", "http://www.metacyc.org" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_pir" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_pir" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "primary metabolism" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/26424" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] @@ -8847,12 +8871,15 @@ "val" : "The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.", "xrefs" : [ "GO_REF:0000021" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_plant" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_plant" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "development of an anatomical structure" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/26424" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] @@ -8880,7 +8907,7 @@ "val" : "Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another.", "xrefs" : [ "GOC:dgh", "GOC:dph", "GOC:isa_complete", "GOC:mlg" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cell locomotion" @@ -9082,7 +9109,7 @@ "xrefs" : [ "GOC:ai", "GOC:bf" ] }, "comments" : [ "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ], - "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_manually_annotate", "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_manually_annotate", "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "physiological response to stimulus" @@ -9675,7 +9702,7 @@ "val" : "The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex.", "xrefs" : [ "GOC:jl" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_pombe", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_pombe", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cellular protein complex assembly" @@ -9982,6 +10009,7 @@ "val" : "The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon.", "xrefs" : [ "GOC:mah" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "organic molecular entity metabolic process" @@ -9993,6 +10021,9 @@ "val" : "organic substance metabolism" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/26424" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "mah" }, { @@ -10084,7 +10115,7 @@ "type" : "CLASS", "meta" : { "definition" : { - "val" : "The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures.", + "val" : "The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures.", "xrefs" : [ "GOC:pdt" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon" ], @@ -10717,6 +10748,9 @@ "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/24200" + }, { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/26424" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "kmv" @@ -12438,47 +12472,6 @@ "val" : "quality" } ] } - }, { - "id" : "http://purl.obolibrary.org/obo/PATO_0000068", - "lbl" : "qualitative", - "type" : "CLASS", - "meta" : { - "comments" : [ "TODO: define this or obsolete it and move children somewhere else." ], - "basicPropertyValues" : [ { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", - "val" : "quality" - } ] - } - }, { - "id" : "http://purl.obolibrary.org/obo/PATO_0000069", - "lbl" : "deviation (from_normal)", - "type" : "CLASS", - "meta" : { - "definition" : { - "val" : "A quality inhering in a bearer by virtue of the whether the bearer differs from normal or average.", - "xrefs" : [ "PATOC:GVG" ] - }, - "subsets" : [ "http://purl.obolibrary.org/obo/pato#attribute_slim" ], - "basicPropertyValues" : [ { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", - "val" : "quality" - } ] - } - }, { - "id" : "http://purl.obolibrary.org/obo/PATO_0000117", - "lbl" : "size", - "type" : "CLASS", - "meta" : { - "definition" : { - "val" : "A morphology quality inhering in a bearer by virtue of the bearer's physical magnitude.", - "xrefs" : [ "WordNet:WordNet" ] - }, - "subsets" : [ "http://purl.obolibrary.org/obo/pato#attribute_slim", "http://purl.obolibrary.org/obo/pato#scalar_slim" ], - "basicPropertyValues" : [ { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", - "val" : "quality" - } ] - } }, { "id" : "http://purl.obolibrary.org/obo/PATO_0000141", "lbl" : "structure", @@ -12552,65 +12545,6 @@ "val" : "quality" } ] } - }, { - "id" : "http://purl.obolibrary.org/obo/PATO_0000461", - "lbl" : "normal", - "type" : "CLASS", - "meta" : { - "definition" : { - "val" : "A quality inhering in a bearer by virtue of the bearer's exhibiting no deviation from normal or average.", - "xrefs" : [ "PATOC:GVG" ] - }, - "subsets" : [ "http://purl.obolibrary.org/obo/pato#abnormal_slim", "http://purl.obolibrary.org/obo/pato#mpath_slim", "http://purl.obolibrary.org/obo/pato#value_slim" ], - "synonyms" : [ { - "pred" : "hasRelatedSynonym", - "val" : "average" - } ], - "basicPropertyValues" : [ { - "pred" : "http://purl.obolibrary.org/obo/RO_0002604", - "val" : "http://purl.obolibrary.org/obo/PATO_0000460" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", - "val" : "quality" - } ] - } - }, { - "id" : "http://purl.obolibrary.org/obo/PATO_0000586", - "lbl" : "increased size", - "type" : "CLASS", - "meta" : { - "definition" : { - "val" : "A size quality which is relatively high.", - "xrefs" : [ "PATOC:GVG" ] - }, - "subsets" : [ "http://purl.obolibrary.org/obo/pato#value_slim" ], - "synonyms" : [ { - "pred" : "hasRelatedSynonym", - "val" : "big" - }, { - "pred" : "hasRelatedSynonym", - "val" : "enlarged" - }, { - "pred" : "hasRelatedSynonym", - "val" : "expanded" - }, { - "pred" : "hasRelatedSynonym", - "val" : "great" - }, { - "pred" : "hasRelatedSynonym", - "val" : "large" - } ], - "basicPropertyValues" : [ { - "pred" : "http://purl.obolibrary.org/obo/RO_0002604", - "val" : "http://purl.obolibrary.org/obo/PATO_0000587" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", - "val" : "PATO:0001202" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", - "val" : "quality" - } ] - } }, { "id" : "http://purl.obolibrary.org/obo/PATO_0000947", "lbl" : "elliptic", @@ -13292,52 +13226,6 @@ "val" : "quality" } ] } - }, { - "id" : "http://purl.obolibrary.org/obo/PATO_0002300", - "lbl" : "increased quality", - "type" : "CLASS", - "meta" : { - "definition" : { - "val" : "A quality that has a value that is increased compared to normal or average.", - "xrefs" : [ "PATOC:GVG" ] - }, - "basicPropertyValues" : [ { - "pred" : "http://purl.obolibrary.org/obo/RO_0002604", - "val" : "http://purl.obolibrary.org/obo/PATO_0002301" - }, { - "pred" : "http://purl.org/dc/terms/contributor", - "val" : "https://orcid.org/0000-0002-2061-091X" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", - "val" : "2011-06-16T06:39:43Z" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", - "val" : "quality" - } ] - } - }, { - "id" : "http://purl.obolibrary.org/obo/PATO_0002305", - "lbl" : "increased object quality", - "type" : "CLASS", - "meta" : { - "definition" : { - "val" : "A quality of an object that has a value that is increased compared to normal or average.", - "xrefs" : [ "PATOC:GVG" ] - }, - "basicPropertyValues" : [ { - "pred" : "http://purl.obolibrary.org/obo/RO_0002604", - "val" : "http://purl.obolibrary.org/obo/PATO_0002303" - }, { - "pred" : "http://purl.org/dc/terms/contributor", - "val" : "https://orcid.org/0000-0002-2061-091X" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", - "val" : "2011-06-16T06:54:01Z" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", - "val" : "quality" - } ] - } }, { "id" : "http://purl.obolibrary.org/obo/PATO_0002309", "lbl" : "fiber shaped", @@ -13503,6 +13391,28 @@ "val" : "quality" } ] } + }, { + "id" : "http://purl.obolibrary.org/obo/PATO_0040072", + "lbl" : "high nuclear/cytoplasmic ratio", + "type" : "CLASS", + "meta" : { + "definition" : { + "val" : "A quality inhering in a cell by virtue of the cell having a high nuclear/cytoplasmic ratio.", + "xrefs" : [ "Wikipedia:NC_ratio&oldid=931936284", "http://lymerick.net/blood-cells.pdf" ] + }, + "comments" : [ "A high nuclear/cytolasmic ratio is 70% or higher." ], + "synonyms" : [ { + "pred" : "hasExactSynonym", + "val" : "high N:C ratio" + } ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", + "val" : "http://orcid.org/0000-0001-5208-3432" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "quality" + } ] + } }, { "id" : "http://purl.obolibrary.org/obo/PATO_0070044", "lbl" : "anatomical structure quality", @@ -16341,6 +16251,9 @@ "val" : "inverse of develops from" }, "subsets" : [ "http://purl.obolibrary.org/obo/RO_0002259" ], + "xrefs" : [ { + "val" : "RO:0002203" + } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000114", "val" : "http://purl.obolibrary.org/obo/IAO_0000125" @@ -16353,6 +16266,12 @@ }, { "pred" : "http://purl.obolibrary.org/obo/IAO_0000117", "val" : "https://orcid.org/0000-0003-1980-3228" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "uberon" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#shorthand", + "val" : "develops_into" } ] } }, { @@ -21451,7 +21370,7 @@ "pred" : "hasRelatedSynonym", "val" : "glomerular tuft" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "glomerulus renis", "xrefs" : [ "Wikipedia:Glomerulus" ] @@ -21752,7 +21671,7 @@ "val" : "renal tubules", "xrefs" : [ "VHOG:0000500" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "tubuli mesonephrici", "xrefs" : [ "Wikipedia:Mesonephric_tubules" ] @@ -21799,12 +21718,12 @@ "val" : "diverticulum", "xrefs" : [ "BTO:0001646" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "diverticulum metanephricum", "xrefs" : [ "Wikipedia:Ureteric_bud" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "gemma ureterica", "xrefs" : [ "Wikipedia:Ureteric_bud" ] @@ -22056,7 +21975,7 @@ "val" : "zygote", "xrefs" : [ "VHOG:0000745" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "zygotum", "xrefs" : [ "Wikipedia:Zygote" ] @@ -22559,7 +22478,7 @@ "val" : "fetal UGS", "xrefs" : [ "PMID:18977204" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "sinus urogenitalis" } ], @@ -22610,7 +22529,7 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#efo_slim", "http://purl.obolibrary.org/obo/uberon/core#major_organ", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "regio oralis", "xrefs" : [ "BTO:0004698", "FMA:49184", "FMA:TA" ] @@ -22618,7 +22537,7 @@ "pred" : "hasNarrowSynonym", "val" : "adult mouth" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "cavital oralis", "xrefs" : [ "Wikipedia:Mouth" ] @@ -22975,6 +22894,8 @@ "xrefs" : [ "Wikipedia:Parenchyma" ] }, "xrefs" : [ { + "val" : "BTO:0000999" + }, { "val" : "BTO:0001539" }, { "val" : "EHDAA:3015" @@ -23043,12 +22964,12 @@ "val" : "medulla of kidney", "xrefs" : [ "OBOL:automatic" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "medulla renalis", "xrefs" : [ "FMA:74268", "FMA:TA" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "pyramides renales", "xrefs" : [ "FMA:74268", "FMA:TA" ] @@ -23896,8 +23817,6 @@ "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#common_anatomy", "http://purl.obolibrary.org/obo/uberon/core#upper_level" ], "xrefs" : [ { "val" : "FBbt:00007277" - }, { - "val" : "IDOMAL:0002461" }, { "val" : "VHOG:0001737" } ], @@ -25355,7 +25274,7 @@ "val" : "Anatomical system that has as its parts the organs concerned with reproduction.", "xrefs" : [ "Wikipedia:Reproductive_system" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#efo_slim", "http://purl.obolibrary.org/obo/uberon/core#functional_classification", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], + "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#efo_slim", "http://purl.obolibrary.org/obo/uberon/core#functional_classification", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "genital system" @@ -25386,7 +25305,7 @@ "pred" : "hasRelatedSynonym", "val" : "reproductive tract" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "systemata genitalia", "xrefs" : [ "Wikipedia:Reproductive_system" ] @@ -25421,6 +25340,8 @@ "val" : "HAO:0000895" }, { "val" : "MA:0000326" + }, { + "val" : "MESH:D005835" }, { "val" : "MIAA:0000305" }, { @@ -25445,6 +25366,9 @@ "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000116", "val" : "consider splitting genitalia from reproductive system" + }, { + "pred" : "http://purl.obolibrary.org/obo/RO_0002175", + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" }, { "pred" : "http://purl.obolibrary.org/obo/UBPROP_0000001", "val" : "Anatomical system which consists of organs and tissues associated with sexual reproduction of the organism.[AAO]" @@ -25760,7 +25684,7 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "systema cardiovasculare", "xrefs" : [ "Wikipedia:Circulatory_system" ] @@ -25769,6 +25693,8 @@ "val" : "AAO:0000959" }, { "val" : "CALOHA:TS-2103" + }, { + "val" : "MESH:D002319" }, { "val" : "VHOG:0001248" }, { @@ -25826,7 +25752,7 @@ "pred" : "hasExactSynonym", "val" : "musculature" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "musculi", "xrefs" : [ "FMA:32558", "FMA:TA" ] @@ -25900,7 +25826,7 @@ "val" : "The nervous system is an organ system containing predominantly neuron and glial cells. In bilaterally symmetrical organism, it is arranged in a network of tree-like structures connected to a central body. The main functions of the nervous system are to regulate and control body functions, and to receive sensory input, process this information, and generate behavior [CUMBO].", "xrefs" : [ "BIRNLEX:844", "ISBN:0-14-051288-8", "ISBN:3110148986", "NLM:nervous+system", "WB:rynl", "Wikipedia:Nervous_system", "ZFIN:curator" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#cumbo", "http://purl.obolibrary.org/obo/uberon/core#efo_slim", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], + "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#cumbo", "http://purl.obolibrary.org/obo/uberon/core#efo_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "neurological system", @@ -25910,7 +25836,7 @@ "val" : "nerve net", "xrefs" : [ "Wikipedia:Nerve_net" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "systema nervosum", "xrefs" : [ "Wikipedia:Nervous_system" ] @@ -25973,6 +25899,9 @@ "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_6040" + }, { + "pred" : "http://purl.obolibrary.org/obo/RO_0002175", + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" }, { "pred" : "http://purl.obolibrary.org/obo/UBPROP_0000001", "val" : "A regulatory system of the body that consists of neurons and neuroglial cells. The nervous system is divided into two parts, the central nervous system (CNS) and the peripheral nervous system (PNS). (Source: BioGlossary, www.Biology-Text.com)[TAO]" @@ -26008,13 +25937,13 @@ "val" : "The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the neural tube derivatives: the brain and spinal cord. In invertebrates it includes central ganglia plus nerve cord.", "xrefs" : [ "GO:0021551", "http://www.frontiersinzoology.com/content/7/1/29", "https://sourceforge.net/p/geneontology/ontology-requests/11422/" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#cumbo", "http://purl.obolibrary.org/obo/uberon/core#efo_slim", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], + "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#cumbo", "http://purl.obolibrary.org/obo/uberon/core#efo_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], "synonyms" : [ { "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003000", "pred" : "hasExactSynonym", "val" : "CNS" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "systema nervosum centrale", "xrefs" : [ "FMA:55675", "FMA:TA" ] @@ -26085,6 +26014,9 @@ "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099" + }, { + "pred" : "http://purl.obolibrary.org/obo/RO_0002175", + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" }, { "pred" : "http://purl.obolibrary.org/obo/UBPROP_0000001", "val" : "Part of the nervous system which includes the brain and spinal cord.[AAO]" @@ -26113,12 +26045,12 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#developmental_classification", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "praeenteron", "xrefs" : [ "Wikipedia:Foregut" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "proenteron", "xrefs" : [ "Wikipedia:Foregut" ] @@ -26184,7 +26116,7 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#developmental_classification", "http://purl.obolibrary.org/obo/uberon/core#efo_slim", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "mesenteron", "xrefs" : [ "Wikipedia:Midgut" ] @@ -26253,7 +26185,7 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#developmental_classification", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "metenteron", "xrefs" : [ "Wikipedia:Hindgut" ] @@ -26385,7 +26317,7 @@ "pred" : "hasRelatedSynonym", "val" : "presumptive central nervous system" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "tubus neuralis", "xrefs" : [ "Wikipedia:Neural_tube" ] @@ -26546,7 +26478,7 @@ "pred" : "hasRelatedSynonym", "val" : "postcava" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "vena cava inferior", "xrefs" : [ "BTO:0002682", "Wikipedia:Inferior_vena_cava" ] @@ -26670,7 +26602,7 @@ "val" : "vein of kidney", "xrefs" : [ "OBOL:automatic" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "venae renales", "xrefs" : [ "Wikipedia:Renal_vein" ] @@ -26743,7 +26675,7 @@ "pred" : "hasExactSynonym", "val" : "pelvis of ureter" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "p. renallis", "xrefs" : [ "Wikipedia:Renal_pelvis" ] @@ -26797,7 +26729,7 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "cortex renalis", "xrefs" : [ "FMA:15581", "FMA:TA" ] @@ -26880,11 +26812,11 @@ "val" : "Malpighian corpuscle", "xrefs" : [ "ZFA:0005281" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "corpusculum renale" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "corpusculum renis", "xrefs" : [ "Wikipedia:Renal_corpuscle" ] @@ -26965,7 +26897,7 @@ "val" : "Bowmans capsule", "xrefs" : [ "KUPO:0001001" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "capsula glomerularis" }, { @@ -26994,7 +26926,7 @@ "val" : "Muellerian capsule", "xrefs" : [ "BTO:0002297" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "capsula glomeruli" }, { @@ -27142,7 +27074,7 @@ "val" : "renal collecting tubule", "xrefs" : [ "FMA:15628" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "tubulus renalis arcuatus", "xrefs" : [ "Wikipedia:Connecting_tubule" ] @@ -27300,7 +27232,7 @@ "val" : "bladder", "xrefs" : [ "EHDAA2:0000174" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "vesica urinaria", "xrefs" : [ "Wikipedia:Urinary_bladder" ] @@ -27448,12 +27380,12 @@ "val" : "mature nephron", "xrefs" : [ "EMAPA:28491" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "nephroneum", "xrefs" : [ "Wikipedia:Nephron" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "tubulus renalis", "xrefs" : [ "Wikipedia:Nephron" ] @@ -27543,12 +27475,12 @@ "val" : "renal proximal convoluted tubule", "xrefs" : [ "http://orcid.org/0000-0002-6601-2165" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "tubulus contortus proximalis", "xrefs" : [ "Wikipedia:Proximal_convoluted_tubule" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "tubulus convolutus proximalis" } ], @@ -27603,7 +27535,7 @@ "pred" : "hasExactSynonym", "val" : "Henle's loop" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "ansa nephroni", "xrefs" : [ "Wikipedia:Loop_of_Henle" ] @@ -27795,12 +27727,12 @@ "pred" : "hasRelatedSynonym", "val" : "second convoluted tubule" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "tubulus contortus distalis", "xrefs" : [ "Wikipedia:Distal_convoluted_tubule" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "tubulus convolutus distalis" } ], @@ -27862,12 +27794,12 @@ "val" : "renal outer medulla", "xrefs" : [ "BTO:0001746" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "zona externa (medullaris renalis)", "xrefs" : [ "FMA:17733", "FMA:TA" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "zona externa medullae renalis", "xrefs" : [ "FMA:17733", "FMA:TA" ] @@ -28126,6 +28058,8 @@ "val" : "FMA:45615" }, { "val" : "MA:0000917" + }, { + "val" : "MESH:D041981" }, { "val" : "NCIT:C34082" }, { @@ -28181,7 +28115,7 @@ "val" : "Subdivision of urinary system which consists of the urinary bladder and the urethra.", "xrefs" : [ "FMA:45659" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim" ], "xrefs" : [ { "val" : "FMA:45659" }, { @@ -28192,6 +28126,9 @@ "val" : "galen:LowerUrinaryTract" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/RO_0002175", + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "uberon" } ] @@ -28376,7 +28313,7 @@ "val" : "vascular element", "xrefs" : [ "EMAPA:th" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "vena", "xrefs" : [ "Wikipedia:Vein" ] @@ -28564,7 +28501,7 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "venula", "xrefs" : [ "Wikipedia:Venule" ] @@ -28619,7 +28556,7 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "arteriola", "xrefs" : [ "Wikipedia:Arteriole" ] @@ -28688,7 +28625,7 @@ "val" : "vascular tree organ region", "xrefs" : [ "FMA:50722" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "vas sanguineum", "xrefs" : [ "Wikipedia:Blood_vessel" ] @@ -29112,7 +29049,7 @@ "pred" : "hasExactSynonym", "val" : "right cardiac atrium" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "atrium dextrum", "xrefs" : [ "Wikipedia:Right_atrium" ] @@ -29297,6 +29234,8 @@ "val" : "MA:0002986" }, { "val" : "MAT:0000148" + }, { + "val" : "MESH:D013131" }, { "val" : "MIAA:0000148" }, { @@ -29352,7 +29291,7 @@ "pred" : "hasNarrowSynonym", "val" : "paired fin skeleton" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "skeleton appendiculare", "xrefs" : [ "Wikipedia:Appendicular_skeleton" ] @@ -29809,7 +29748,7 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "cavitas thoracis", "xrefs" : [ "Wikipedia:Thoracic_cavity" ] @@ -29877,7 +29816,7 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "complexus juxtaglomerularis" }, { @@ -30089,7 +30028,7 @@ "val" : "notocord", "xrefs" : [ "ZFA:0000135" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "notochorda", "xrefs" : [ "Wikipedia:Notochord" ] @@ -30202,7 +30141,7 @@ "pred" : "hasRelatedSynonym", "val" : "somitic mesoderm" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "somitus", "xrefs" : [ "Wikipedia:Somite" ] @@ -30336,7 +30275,7 @@ "val" : "NC", "xrefs" : [ "XAO:0000048" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "crista neuralis", "xrefs" : [ "Wikipedia:Neural_crest" ] @@ -30430,7 +30369,7 @@ "pred" : "hasExactSynonym", "val" : "neuroectoderm" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "epithelium tubi neuralis; neuroectoderma", "xrefs" : [ "Wikipedia:Neuroectoderm" ] @@ -30870,7 +30809,7 @@ "val" : "ectoblast", "xrefs" : [ "MP:0003886" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "epiblastus", "xrefs" : [ "Wikipedia:Epiblast" ] @@ -31017,7 +30956,7 @@ "val" : "archinephric duct", "xrefs" : [ "VHOG:0000082" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "ductus pronephricus", "xrefs" : [ "Wikipedia:Pronephric_duct" ] @@ -31164,7 +31103,7 @@ "val" : "intermediate plate mesoderm", "xrefs" : [ "https://orcid.org/0000-0002-6601-2165" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "mesenchyma intermedium", "xrefs" : [ "Wikipedia:Intermediate_mesoderm" ] @@ -31275,7 +31214,7 @@ "val" : "archinephric duct", "xrefs" : [ "VHOG:0000082", "Wikipedia:Wolffian_duct" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "ductus mesonephricus; ductus Wolffi", "xrefs" : [ "Wikipedia:Mesonephric_duct" ] @@ -31351,7 +31290,7 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "lamina neuralis", "xrefs" : [ "Wikipedia:Neural_plate" ] @@ -31429,7 +31368,7 @@ "val" : "somitic mesoderm", "xrefs" : [ "ISBN:9780878932504" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "mesoderma paraxiale", "xrefs" : [ "Wikipedia:Paraxial_mesoderm" ] @@ -31505,7 +31444,7 @@ "val" : "lateral plate mesenchyme", "xrefs" : [ "EHDAA2:0000919" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "mesoderma laminae lateralis", "xrefs" : [ "Wikipedia:Lateral_plate_mesoderm" ] @@ -31626,7 +31565,7 @@ "val" : "sclerotomes", "xrefs" : [ "TAO:0001080" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "sclerotomus", "xrefs" : [ "Wikipedia:Sclerotome" ] @@ -31745,7 +31684,7 @@ "pred" : "hasExactSynonym", "val" : "portion of mesenchyme tissue" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "mesenchyma", "xrefs" : [ "Wikipedia:Mesenchyme" ] @@ -32486,7 +32425,7 @@ "val" : "kidney collecting duct system", "xrefs" : [ "Wikipedia:Collecting_duct_system" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "tubulus renalis colligens", "xrefs" : [ "Wikipedia:Collecting_duct_system" ] @@ -33131,6 +33070,8 @@ } ], "xrefs" : [ { "val" : "EMAPA:27756" + }, { + "val" : "VO:0010896" }, { "val" : "ZFA:0005589" } ], @@ -33185,7 +33126,7 @@ "val" : "pyramid of Malpighi", "xrefs" : [ "UBERON:cjm" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "pyramides renales", "xrefs" : [ "Wikipedia:Renal_pyramids" ] @@ -33283,7 +33224,7 @@ "val" : "outer stripe of renal medulla", "xrefs" : [ "FMA:76662" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "stria externa medullae renalis", "xrefs" : [ "FMA:76662", "FMA:TA" ] @@ -33820,7 +33761,7 @@ "val" : "An endothelium that lines the blood vasculature. Other endothelia may line lymph vessels, the heart.", "xrefs" : [ "https://orcid.org/0000-0002-6601-2165" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], + "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], "xrefs" : [ { "val" : "BTO:0000766" }, { @@ -33839,6 +33780,9 @@ "val" : "ZFA:0005257" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/RO_0002175", + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "uberon" } ] @@ -33866,7 +33810,7 @@ "val" : "afferent glomerular arteriole of kidney", "xrefs" : [ "FMA:77042" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "arteriola glomerularis afferens renis", "xrefs" : [ "FMA:77042", "FMA:TA" ] @@ -33875,7 +33819,7 @@ "val" : "kidney afferent arteriole", "xrefs" : [ "MP:0011312" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "arteriola glomerularis afferens", "xrefs" : [ "Wikipedia:Afferent_arterioles" ] @@ -33965,12 +33909,12 @@ "val" : "kidney interlobular artery", "xrefs" : [ "MP:0011316" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "arteriae corticales radiatae", "xrefs" : [ "Wikipedia:Interlobular_arteries" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "arteriae interlobulares renis", "xrefs" : [ "Wikipedia:Interlobular_arteries" ] @@ -34395,7 +34339,7 @@ }, "comments" : [ "part_of or develops_from urogenital ridge?" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "chorda nephrogenica", "xrefs" : [ "Wikipedia:Nephrogenic_cord" ] @@ -34761,7 +34705,7 @@ "type" : "CLASS", "meta" : { "definition" : { - "val" : ".", + "val" : "Missing definition for term UBERON:0005095. Please replace it using linked reference.", "xrefs" : [ "GO:0072003" ] }, "synonyms" : [ { @@ -34870,7 +34814,7 @@ "val" : "kidney connecting tubule", "xrefs" : [ "MA:0002610" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "tubulus renalis arcuatus", "xrefs" : [ "Wikipedia:Connecting_tubule" ] @@ -35697,7 +35641,7 @@ "val" : "basement membrane of connective tissue", "xrefs" : [ "FMA:63872" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "membrana basalis", "xrefs" : [ "Wikipedia:Basement_membrane" ] @@ -35857,7 +35801,7 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "skeleton axiale", "xrefs" : [ "Wikipedia:Axial_skeleton" ] @@ -35914,7 +35858,7 @@ "pred" : "hasExactSynonym", "val" : "embryonic cloacal membrane" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "membrana cloacalis", "xrefs" : [ "Wikipedia:Cloacal_membrane" ] @@ -37447,7 +37391,7 @@ "val" : "renal interlobar artery", "xrefs" : [ "MP:0011355" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "arteriae interlobares renis", "xrefs" : [ "Wikipedia:Interlobar_arteries" ] @@ -37494,7 +37438,7 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#upper_level" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "lobus", "xrefs" : [ "FMA:45728", "FMA:TA" ] @@ -37535,7 +37479,7 @@ "val" : "lobus renalis", "xrefs" : [ "http://www.mondofacto.com/facts/dictionary?lobus+renalis" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "lobi renales", "xrefs" : [ "Wikipedia:Renal_lobe" ] @@ -38058,7 +38002,7 @@ "val" : "A subdivision of an anatomical system.", "xrefs" : [ "http://orcid.org/0000-0002-6601-2165" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#common_anatomy", "http://purl.obolibrary.org/obo/uberon/core#upper_level" ], + "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#common_anatomy", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#upper_level" ], "xrefs" : [ { "val" : "FBbt:00007330" }, { @@ -38075,6 +38019,9 @@ }, { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_4751" + }, { + "pred" : "http://purl.obolibrary.org/obo/RO_0002175", + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "uberon" @@ -38377,7 +38324,7 @@ "xrefs" : [ "http://orcid.org/0000-0002-6601-2165" ] }, "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "sulcus urethralis primarius", "xrefs" : [ "Wikipedia:Urethral_groove" ] @@ -38466,7 +38413,7 @@ "val" : "The region of the organism associated with the visceral organs.", "xrefs" : [ "AEO:0000103" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#non_informative" ], + "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#non_informative" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "body", @@ -38486,9 +38433,6 @@ "val" : "FMA:231424" } ], "basicPropertyValues" : [ { - "pred" : "http://purl.obolibrary.org/obo/RO_0002175", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" - }, { "pred" : "http://purl.obolibrary.org/obo/UBPROP_0000001", "val" : "Cardinal body part, which consists of a maximal set of diverse subclasses of organ and organ part spatially associated with the vertebral column and ribcage. Examples: There is only one body proper[FMA:231424]." }, { @@ -39054,6 +38998,7 @@ "val" : "The upper tract of the renal system. The renal pelvis is the large cavity in the middle of each kidney. Urine drains from each kidney through a long tube called the ureter, into the bladder, where it is stored until it is passed from the body through the urethra.", "xrefs" : [ "NCIT:C54419" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "renal pelvis and ureter" @@ -39065,6 +39010,9 @@ "val" : "NCIT:C54419" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/RO_0002175", + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "uberon" } ] @@ -39185,8 +39133,10 @@ "val" : "OBSOLETE A relation between a cell and molecule or complex such that every instance of the cell has a high number of instances of that molecule expressed on the cell surface. For the formal definition, see Masci et al (PMID:19243617).", "xrefs" : [ "PMID:19243617" ] }, - "comments" : [ "Replaced with RO:0015015, see https://github.com/obophenotype/cell-ontology/issues/1481" ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/obophenotype/cell-ontology/issues/1481" + }, { "pred" : "http://purl.obolibrary.org/obo/IAO_0100001", "val" : "http://purl.obolibrary.org/obo/RO_0015015" } ], @@ -39201,8 +39151,10 @@ "val" : "OBSOLETE A relation between a cell and molecule or complex such that every instance of the cell has a low number of instances of that molecule expressed on the cell surface. For the formal definition, see Masci et al (PMID:19243617).", "xrefs" : [ "PMID:19243617" ] }, - "comments" : [ "Replaced with RO:0015016, see https://github.com/obophenotype/cell-ontology/issues/1481" ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/obophenotype/cell-ontology/issues/1481" + }, { "pred" : "http://purl.obolibrary.org/obo/IAO_0100001", "val" : "http://purl.obolibrary.org/obo/RO_0015016" } ], @@ -39432,13 +39384,12 @@ "lbl" : "transitively anteriorly connected to", "type" : "PROPERTY", "meta" : { - "definition" : { - "val" : ".", - "xrefs" : [ "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" ] - }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "uberon" + }, { + "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", + "val" : "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" } ] } }, { @@ -39446,13 +39397,12 @@ "lbl" : "transitively distally connected to", "type" : "PROPERTY", "meta" : { - "definition" : { - "val" : ".", - "xrefs" : [ "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" ] - }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "uberon" + }, { + "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", + "val" : "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" } ] } }, { @@ -39460,13 +39410,12 @@ "lbl" : "transitively proximally connected to", "type" : "PROPERTY", "meta" : { - "definition" : { - "val" : ".", - "xrefs" : [ "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" ] - }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "uberon" + }, { + "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", + "val" : "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" } ] } }, { @@ -40312,10 +40261,6 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0000547", "pred" : "http://purl.obolibrary.org/obo/BFO_0000051", "obj" : "http://purl.obolibrary.org/obo/CL_0017503" - }, { - "sub" : "http://purl.obolibrary.org/obo/CL_0000547", - "pred" : "http://purl.obolibrary.org/obo/BFO_0000051", - "obj" : "http://purl.obolibrary.org/obo/CL_0017505" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000547", "pred" : "http://purl.obolibrary.org/obo/BFO_0000051", @@ -40364,6 +40309,10 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0000547", "pred" : "http://purl.obolibrary.org/obo/CL_4030046", "obj" : "http://purl.obolibrary.org/obo/PR_000002978" + }, { + "sub" : "http://purl.obolibrary.org/obo/CL_0000547", + "pred" : "http://purl.obolibrary.org/obo/RO_0000053", + "obj" : "http://purl.obolibrary.org/obo/PATO_0040072" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000547", "pred" : "http://purl.obolibrary.org/obo/RO_0002104", @@ -41232,14 +41181,6 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0017504", "pred" : "http://purl.obolibrary.org/obo/RO_0000053", "obj" : "http://purl.obolibrary.org/obo/PATO_0070047" - }, { - "sub" : "http://purl.obolibrary.org/obo/CL_0017505", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/GO_0005634" - }, { - "sub" : "http://purl.obolibrary.org/obo/CL_0017505", - "pred" : "http://purl.obolibrary.org/obo/RO_0000053", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000586" }, { "sub" : "http://purl.obolibrary.org/obo/CL_1000449", "pred" : "is_a", @@ -44340,18 +44281,6 @@ "sub" : "http://purl.obolibrary.org/obo/PATO_0000052", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/PATO_0000051" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0000068", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000001" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0000069", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000068" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0000117", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000051" }, { "sub" : "http://purl.obolibrary.org/obo/PATO_0000141", "pred" : "is_a", @@ -44364,18 +44293,6 @@ "sub" : "http://purl.obolibrary.org/obo/PATO_0000411", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/PATO_0000947" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0000461", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000068" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0000586", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000117" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0000586", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0002305" }, { "sub" : "http://purl.obolibrary.org/obo/PATO_0000947", "pred" : "is_a", @@ -44524,22 +44441,6 @@ "sub" : "http://purl.obolibrary.org/obo/PATO_0002299", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/PATO_0002078" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0002300", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000069" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0002300", - "pred" : "http://purl.obolibrary.org/obo/RO_0015007", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000461" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0002305", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0001241" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0002305", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0002300" }, { "sub" : "http://purl.obolibrary.org/obo/PATO_0002309", "pred" : "is_a", @@ -44572,6 +44473,10 @@ "sub" : "http://purl.obolibrary.org/obo/PATO_0015008", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/PATO_0000141" + }, { + "sub" : "http://purl.obolibrary.org/obo/PATO_0040072", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/PATO_0001396" }, { "sub" : "http://purl.obolibrary.org/obo/PATO_0070044", "pred" : "is_a", @@ -52781,9 +52686,6 @@ "restrictions" : [ { "propertyId" : "http://purl.obolibrary.org/obo/BFO_0000051", "fillerId" : "http://purl.obolibrary.org/obo/CL_0017503" - }, { - "propertyId" : "http://purl.obolibrary.org/obo/BFO_0000051", - "fillerId" : "http://purl.obolibrary.org/obo/CL_0017505" }, { "propertyId" : "http://purl.obolibrary.org/obo/BFO_0000051", "fillerId" : "http://purl.obolibrary.org/obo/GO_0005730" @@ -52823,6 +52725,9 @@ }, { "propertyId" : "http://purl.obolibrary.org/obo/RO_0000053", "fillerId" : "http://purl.obolibrary.org/obo/PATO_0002505" + }, { + "propertyId" : "http://purl.obolibrary.org/obo/RO_0000053", + "fillerId" : "http://purl.obolibrary.org/obo/PATO_0040072" }, { "propertyId" : "http://purl.obolibrary.org/obo/RO_0002104", "fillerId" : "http://purl.obolibrary.org/obo/PR_000001945" @@ -53245,13 +53150,6 @@ "propertyId" : "http://purl.obolibrary.org/obo/RO_0000053", "fillerId" : "http://purl.obolibrary.org/obo/PATO_0070047" } ] - }, { - "definedClassId" : "http://purl.obolibrary.org/obo/CL_0017505", - "genusIds" : [ "http://purl.obolibrary.org/obo/GO_0005634" ], - "restrictions" : [ { - "propertyId" : "http://purl.obolibrary.org/obo/RO_0000053", - "fillerId" : "http://purl.obolibrary.org/obo/PATO_0000586" - } ] }, { "definedClassId" : "http://purl.obolibrary.org/obo/CL_1000449", "genusIds" : [ "http://purl.obolibrary.org/obo/CL_0000066" ], @@ -54424,27 +54322,6 @@ "propertyId" : "http://purl.obolibrary.org/obo/RO_0002588", "fillerId" : "http://purl.obolibrary.org/obo/GO_0035869" } ] - }, { - "definedClassId" : "http://purl.obolibrary.org/obo/PATO_0000586", - "genusIds" : [ "http://purl.obolibrary.org/obo/PATO_0000117" ], - "restrictions" : [ { - "propertyId" : "http://purl.obolibrary.org/obo/RO_0015007", - "fillerId" : "http://purl.obolibrary.org/obo/PATO_0000461" - } ] - }, { - "definedClassId" : "http://purl.obolibrary.org/obo/PATO_0002300", - "genusIds" : [ "http://purl.obolibrary.org/obo/PATO_0000001" ], - "restrictions" : [ { - "propertyId" : "http://purl.obolibrary.org/obo/RO_0015007", - "fillerId" : "http://purl.obolibrary.org/obo/PATO_0000461" - } ] - }, { - "definedClassId" : "http://purl.obolibrary.org/obo/PATO_0002305", - "genusIds" : [ "http://purl.obolibrary.org/obo/PATO_0001241" ], - "restrictions" : [ { - "propertyId" : "http://purl.obolibrary.org/obo/RO_0015007", - "fillerId" : "http://purl.obolibrary.org/obo/PATO_0000461" - } ] }, { "definedClassId" : "http://purl.obolibrary.org/obo/PR_000029032", "genusIds" : [ "http://purl.obolibrary.org/obo/PR_000000001" ], diff --git a/src/ontology/subsets/kidney_upper_slim.obo b/src/ontology/subsets/kidney_upper_slim.obo index b7ccbe436..161bb5549 100644 --- a/src/ontology/subsets/kidney_upper_slim.obo +++ b/src/ontology/subsets/kidney_upper_slim.obo @@ -1,5 +1,5 @@ format-version: 1.2 -data-version: cl/releases/2024-01-04/subsets/kidney_upper_slim.owl +data-version: cl/releases/2024-02-13/subsets/kidney_upper_slim.owl subsetdef: abnormal_slim "" subsetdef: added_for_HCA "" subsetdef: attribute_slim "" @@ -31,6 +31,7 @@ subsetdef: goslim_mouse "" subsetdef: goslim_pir "" subsetdef: goslim_plant "" subsetdef: goslim_pombe "" +subsetdef: goslim_prokaryote "" subsetdef: goslim_synapse "" subsetdef: goslim_yeast "" subsetdef: grouping_class "" @@ -49,7 +50,6 @@ subsetdef: non_informative "" subsetdef: organ_slim "" subsetdef: pheno_slim "" subsetdef: phenotype_rcn "" -subsetdef: prokaryote_subset "" subsetdef: ro-eco "" subsetdef: RO:0002259 "" subsetdef: scalar_slim "" @@ -62,7 +62,6 @@ subsetdef: vertebrate_core "" synonymtypedef: blast_name "" synonymtypedef: COMPARATIVE_PREFERRED "" synonymtypedef: DEPRECATED "" -synonymtypedef: DUBIOUS "" synonymtypedef: equivalent_name "" synonymtypedef: genbank_common_name "" synonymtypedef: Gene-based "" @@ -71,13 +70,14 @@ synonymtypedef: HUMAN_PREFERRED "" synonymtypedef: HUMAN_PREFERRED "preferred term when talking about an instance of this class in Homo sapiens" synonymtypedef: in_part "" synonymtypedef: INCONSISTENT "" -synonymtypedef: LATIN "" synonymtypedef: LATIN "latin term" synonymtypedef: MISSPELLING "a mis-spelling that is in common use and thus recorded" synonymtypedef: NON_MAMMAL "" synonymtypedef: OMO:0003000 "abbreviation" +synonymtypedef: OMO:0003002 "" synonymtypedef: OMO:0003003 "" synonymtypedef: OMO:0003004 "plural form" +synonymtypedef: OMO:0003011 "" synonymtypedef: PENDING_REVIEW "" synonymtypedef: PLURAL "plural term" synonymtypedef: PRO-short-label "" @@ -88,7 +88,7 @@ synonymtypedef: synonym "" synonymtypedef: SYSTEMATIC "" synonymtypedef: systematic_synonym "" ontology: cl/subsets/kidney_upper_slim -property_value: owl:versionInfo "2024-01-04" xsd:string +property_value: owl:versionInfo "2024-02-13" xsd:string [Term] id: BFO:0000002 @@ -144,6 +144,7 @@ id: CL:0000000 name: cell def: "A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane." [CARO:mah] comment: The definition of cell is intended to represent all cells, and thus a cell is defined as a material entity and not an anatomical structure, which implies that it is part of an organism (or the entirety of one). +subset: cellxgene_subset subset: ubprop:upper_level xref: CALOHA:TS-2035 xref: FBbt:00007002 @@ -171,6 +172,7 @@ id: CL:0000034 name: stem cell def: "A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells." [GOC:tfm, MESH:D013234] comment: This term applies to metazoan. For plant stem cells, consider using PO:0004011 ‘initial cell’ or its parent PO:0004010 ‘meristematic cell’. +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "animal stem cell" EXACT [] @@ -189,6 +191,7 @@ name: hematopoietic stem cell def: "A stem cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system. Hematopoietic stem cells lack cell markers of effector cells (lin-negative). Lin-negative is defined by lacking one or more of the following cell surface markers: CD2, CD3 epsilon, CD4, CD5 ,CD8 alpha chain, CD11b, CD14, CD19, CD20, CD56, ly6G, ter119." [GOC:add, GOC:dsd, GOC:tfm, http://en.wikipedia.org/wiki/Hematopoietic_stem_cell, PMID:19022770] comment: Markers differ between species, and two sets of markers have been described for mice. HSCs are reportedly CD34-positive, CD45-positive, CD48-negative, CD150-positive, CD133-positive, and CD244-negative. subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "blood forming stem cell" EXACT [] synonym: "colony forming unit hematopoietic" RELATED [] @@ -238,6 +241,7 @@ id: CL:0000038 name: erythroid progenitor cell def: "A progenitor cell committed to the erythroid lineage." [GOC:add, ISBN:0721601464] subset: blood_and_immune_upper_slim +subset: cellxgene_subset synonym: "BFU-E" RELATED OMO:0003000 [] synonym: "blast forming unit erythroid" RELATED [] synonym: "burst forming unit erythroid" RELATED [] @@ -279,6 +283,7 @@ id: CL:0000049 name: common myeloid progenitor def: "A progenitor cell committed to myeloid lineage, including the megakaryocyte and erythroid lineages." [GOC:add, ISBN:0878932437, MESH:D023461] comment: This cell type is intended to be compatible with any vertebrate common myeloid progenitor. For mammalian CMP known to be CD34-positive, please use the term 'common myeloid progenitor, CD34-positive' (CL_0001059). +subset: cellxgene_subset subset: human_reference_atlas synonym: "CFU-GEMM" RELATED OMO:0003000 [ISBN:0878932437] synonym: "CFU-S" RELATED OMO:0003000 [ISBN:0878932437] @@ -298,6 +303,7 @@ id: CL:0000050 name: megakaryocyte-erythroid progenitor cell def: "A progenitor cell committed to the megakaryocyte and erythroid lineages." [GOC:add, GOC:dsd, GOC:tfm, http://en.wikipedia.org/wiki/Megakaryocyte-erythroid_progenitor_cell, MESH:D055015, PMID:16647566] comment: MEPs are reportedly CD19-negative, CD34-negative, CD45RA-negative, CD110-positive, CD117-positive, and SCA1-negative and reportedly express the transcription factors GATA-1 and NF-E2. +subset: cellxgene_subset subset: human_reference_atlas synonym: "CFU-EM" EXACT [] synonym: "CFU-MegE" EXACT [] @@ -330,6 +336,7 @@ id: CL:0000055 name: non-terminally differentiated cell def: "A precursor cell with a limited number of potential fates." [SANBI:mhl] comment: define using PATO mulit-potent or oligopotent? +subset: cellxgene_subset synonym: "blast cell" EXACT [] xref: BTO:0000125 xref: FMA:84782 @@ -351,6 +358,7 @@ id: CL:0000057 name: fibroblast def: "A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped." [http://en.wikipedia.org/wiki/Fibroblast, ISBN:0517223651, MESH:D005347] comment: These cells may be vimentin-positive, fibronectin-positive, fsp1-positive, MMP-1-positive, collagen I-positive, collagen III-positive, and alpha-SMA-negative. +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas xref: BTO:0000452 @@ -366,6 +374,7 @@ relationship: present_in_taxon NCBITaxon:9606 id: CL:0000064 name: ciliated cell def: "A cell that has a filiform extrusion of the cell surface." [GOC:tfm] +subset: cellxgene_subset xref: VHOG:0001532 xref: XAO:0000031 is_a: CL:0000000 ! cell @@ -378,6 +387,7 @@ relationship: has_part GO:0005929 ! cilium id: CL:0000066 name: epithelial cell def: "A cell that is usually found in a two-dimensional sheet with a free surface. The cell has a cytoskeleton that allows for tight cell to cell contact and for cell polarity where apical part is directed towards the lumen and the basal part to the basal lamina." [FB:ma, GOC:tfm, MESH:D004847] +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "epitheliocyte" EXACT [] @@ -396,6 +406,7 @@ property_value: depiction "https://www.swissbiopics.org/api/image/Epithelial_cel id: CL:0000067 name: ciliated epithelial cell def: "An epithelial cell that has a cilia." [GOC:tfm] +subset: cellxgene_subset xref: FMA:70605 is_a: CL:0000064 ! ciliated cell is_a: CL:0000066 ! epithelial cell @@ -406,6 +417,7 @@ intersection_of: has_part GO:0005929 ! cilium id: CL:0000068 name: duct epithelial cell def: "An epithelial cell that is part of a duct." [https://orcid.org/0000-0001-5208-3432] +subset: cellxgene_subset is_a: CL:0000066 ! epithelial cell intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0000058 ! duct @@ -415,6 +427,7 @@ relationship: part_of UBERON:0000058 ! duct id: CL:0000071 name: blood vessel endothelial cell def: "An endothelial cell that lines the vasculature." [GOC:tfm] +subset: cellxgene_subset subset: human_reference_atlas synonym: "cuboidal endothelial cell of vascular tree" EXACT [] is_a: CL:0000076 {is_inferred="true"} ! squamous epithelial cell @@ -435,6 +448,7 @@ is_a: CL:0002078 ! meso-epithelial cell id: CL:0000075 name: columnar/cuboidal epithelial cell def: "A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube." [GO:0002065, https://orcid.org/0000-0001-5208-3432] +subset: cellxgene_subset subset: human_reference_atlas is_a: CL:0000066 ! epithelial cell relationship: present_in_taxon NCBITaxon:9606 @@ -442,6 +456,7 @@ relationship: present_in_taxon NCBITaxon:9606 [Term] id: CL:0000076 name: squamous epithelial cell +subset: cellxgene_subset xref: CALOHA:TS-1249 is_a: CL:0000066 ! epithelial cell @@ -449,6 +464,7 @@ is_a: CL:0000066 ! epithelial cell id: CL:0000081 name: blood cell def: "A cell found predominately in the blood." [GOC:add, GOC:tfm] +subset: cellxgene_subset subset: general_cell_types_upper_slim xref: FMA:62844 xref: MESH:D001773 @@ -462,6 +478,7 @@ id: CL:0000115 name: endothelial cell def: "An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal. In mammals, endothelial cell has vimentin filaments and is derived from the mesoderm." [GOC:tfm, http://en.wikipedia.org/wiki/Endothelial_cell, https://sourceforge.net/tracker/?func=detail&atid=440764&aid=3364936&group_id=36855, MESH:D042783, PMID:21275341] comment: From FMA: 9.07.2001: Endothelial cell has always been classified as a kind of epithelial cell, specifically a squamous cell but that is not true. First, endothelial cell can either be squamous or cuboidal (e.g. high-endothelial cell) and secondly, it has different embryological derivation (mesodermal) than a true epithelial cell (ectodermal and endodermal). The basis for present classification is the fact that it comprises the outermost layer or lining of anatomical structures (location-based) but a better structural basis for the differentia is the cytoskeleton of the cell. Endothelial cell has vimentin filaments while an epithelial cell has keratin filaments. [Onard]. +subset: cellxgene_subset subset: human_reference_atlas synonym: "endotheliocyte" EXACT [] xref: BTO:0001176 @@ -483,6 +500,7 @@ id: CL:0000134 name: mesenchymal stem cell def: "A connective tissue cell that normally gives rise to other cells that are organized as three-dimensional masses. In humans, this cell type is CD73-positive, CD90-positive, CD105-positive, CD45-negative, CD34-negative, and MHCII-negative. They may further differentiate into osteoblasts, adipocytes, myocytes, neurons, or chondroblasts in vitro. Originally described as residing in the bone marrow, this cell type is now known to reside in many, if not all, adult organs." [FB:ma, GOC:dsd, http://en.wikipedia.org/wiki/Mesenchymal_stem_cell, http://www.copewithcytokines.de/cope.cgi?key=mesenchymal%20stem%20cells, PMCID:PMC2613570, PMID:10102814, PMID:16923606, PMID:17986482, PMID:19960544] comment: Many but not all mesenchymal cells derive from the mesoderm. MSCs are reportedly CD3-negative, CD4-negative, CD5-negative, CD8-negative, CD11a-negative, CD11b-negative, CD14-negative, CD19-negative, CD29-positive, CD31-negative, CD34-negative, CD38-negative, CD40-negative, CD44-positive, CD45-negative, CD49-positive, CD54-positive, CD66b-negative, CD79a-negative, CD80-negative, CD102-positive, CD106-positive, CD117-positive, CD121a-positive, CD121b-positive, CD123-positive, CD124-positive, CD133-negative, CD146-positive, CD166-positive, CD271-positive, B220-negative, Gr1-negative, MHCI-positive, MHCII-negative, SSEA4-negative, sca1-positive, Ter119-negative, and glycophorin A-negative. Cultured MSCs are capable of producing stem cell factor, IL7, IL8, IL11, TGF-beta, cofilin, galectin-1, laminin-receptor 1, cyclophilin A, and MMP-2. +subset: cellxgene_subset synonym: "BMSC" RELATED OMO:0003000 [] synonym: "bone marrow stromal cells" NARROW [] synonym: "CFU-F" RELATED OMO:0003000 [] @@ -506,6 +524,7 @@ property_value: seeAlso "https://github.com/obophenotype/cell-ontology/issues/47 id: CL:0000151 name: secretory cell def: "A cell that specializes in controlled release of one or more substances." [GOC:tfm, ISBN:0721662544] +subset: cellxgene_subset xref: BTO:0003659 xref: FMA:86916 is_a: CL:0000000 ! cell @@ -525,12 +544,14 @@ relationship: capable_of GO:0009306 ! protein secretion id: CL:0000183 name: contractile cell def: "A cell whose primary function is to shorten." [FB:ma] +subset: cellxgene_subset is_a: CL:0000000 ! cell [Term] id: CL:0000187 name: muscle cell def: "A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns." [MESH:D032342] +subset: cellxgene_subset synonym: "muscle fiber" EXACT [] synonym: "myocyte" EXACT [] xref: BTO:0000888 @@ -548,6 +569,7 @@ property_value: depiction "https://www.swissbiopics.org/api/image/Muscle_cells.s id: CL:0000192 name: smooth muscle cell def: "A non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels. They develop from specialized myoblasts (smooth muscle myoblast)." [http://en.wikipedia.org/wiki/Smooth_muscle_cell, MESH:D032389, PMID:9315361] +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "myocytes, smooth muscle" EXACT [MESH:D032389] @@ -603,6 +625,7 @@ relationship: part_of UBERON:0000924 ! ectoderm id: CL:0000222 name: mesodermal cell def: "A cell of the middle germ layer of the embryo." [MESH:D008648] +subset: cellxgene_subset synonym: "mesoblast" EXACT [] synonym: "mesoderm cell" EXACT [] xref: FMA:72554 @@ -623,6 +646,7 @@ id: CL:0000232 name: erythrocyte def: "A red blood cell. In mammals, mature erythrocytes are biconcave disks containing hemoglobin whose function is to transport oxygen." [GOC:tfm, MESH:D004912] subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "RBC" EXACT [] synonym: "red blood cell" EXACT [] @@ -653,6 +677,7 @@ is_a: CL:0000075 ! columnar/cuboidal epithelial cell [Term] id: CL:0000255 name: eukaryotic cell +subset: cellxgene_subset xref: MESH:D005057 is_a: CL:0000000 ! cell intersection_of: CL:0000000 ! cell @@ -720,19 +745,21 @@ is_a: CL:0000211 ! electrically active cell id: CL:0000514 name: smooth muscle myoblast def: "A precursor cell destined to differentiate into smooth muscle myocytes." [GOC:tfm, MESH:D032390] +subset: cellxgene_subset synonym: "myoblast, smooth muscle" EXACT [MESH:D032390] synonym: "satellite cell" RELATED [] xref: FMA:84798 is_a: CL:0000056 ! myoblast intersection_of: CL:0000056 ! myoblast -intersection_of: RO:0002203 CL:0000192 ! develops into smooth muscle cell -relationship: RO:0002203 CL:0000192 ! develops into smooth muscle cell +intersection_of: develops_into CL:0000192 ! smooth muscle cell +relationship: develops_into CL:0000192 ! smooth muscle cell [Term] id: CL:0000540 name: neuron def: "The basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system." [http://en.wikipedia.org/wiki/Neuron, MESH:D009474] comment: These cells are also reportedly CD4-negative and CD200-positive. They are also capable of producing CD40L and IFN-gamma. +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "nerve cell" EXACT [] @@ -754,6 +781,7 @@ id: CL:0000547 name: proerythroblast def: "An immature, nucleated erythrocyte occupying the stage of erythropoeisis that follows formation of erythroid progenitor cells. This cell is CD71-positive, has both a nucleus and a nucleolus, and lacks hematopoeitic lineage markers." [ISBN:0721601464, PMID:1638021] subset: blood_and_immune_upper_slim +subset: cellxgene_subset synonym: "pronormoblast" RELATED [] synonym: "rubriblast" EXACT [ISBN:0721601464] xref: FMA:83518 @@ -762,6 +790,7 @@ is_a: CL:0002242 ! nucleate cell is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000764 ! erythroid lineage cell intersection_of: bearer_of PATO:0002505 ! nucleated +intersection_of: bearer_of PATO:0040072 ! high nuclear/cytoplasmic ratio intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M @@ -774,9 +803,9 @@ intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell sur intersection_of: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule intersection_of: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G intersection_of: has_part CL:0017503 ! basophilic cytoplasm -intersection_of: has_part CL:0017505 ! increased nucleus size intersection_of: has_part GO:0005730 ! nucleolus intersection_of: RO:0002104 PR:000001945 ! has plasma membrane part transferrin receptor protein 1 +relationship: bearer_of PATO:0040072 ! high nuclear/cytoplasmic ratio relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M @@ -790,7 +819,6 @@ relationship: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule relationship: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G relationship: develops_from CL:0000038 ! erythroid progenitor cell relationship: has_part CL:0017503 ! basophilic cytoplasm -relationship: has_part CL:0017505 ! increased nucleus size relationship: has_part GO:0005730 ! nucleolus relationship: RO:0002104 PR:000001945 ! has plasma membrane part transferrin receptor protein 1 @@ -858,6 +886,7 @@ id: CL:0000553 name: megakaryocyte progenitor cell def: "The earliest cytologically identifiable precursor in the thrombocytic series. This cell is capable of endomitosis and lacks expression of hematopoieitic lineage markers (lin-negative)." [GOC:dsd, GOC:tfm, ISBN:0721601464] comment: Lineage negative is described here as CD2-negative, CD3-negative, CD4-negative, CD5-negative, CD8a-negative, CD14-negative, CD19-negative, CD20-negative, CD56-negative, Ly6g-negative, and Ter119-negative. +subset: cellxgene_subset subset: human_reference_atlas synonym: "CFU-Meg" EXACT [PMID:11722431, PMID:12482498] synonym: "colony-forming unit-megakaryocyte" EXACT [] @@ -913,6 +942,7 @@ name: megakaryocyte def: "A large hematopoietic cell (50 to 100 micron) with a lobated nucleus. Once mature, this cell undergoes multiple rounds of endomitosis and cytoplasmic restructuring to allow platelet formation and release." [http://en.wikipedia.org/wiki/Megakaryocyte, ISBN:0721601464, MESH:D008533, PMID:31043076] comment: Megakaryocytes are reportedly CD181-positive and CD182-positive. subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "megacaryocyte" EXACT [] synonym: "megalocaryocyte" EXACT [] @@ -931,6 +961,7 @@ id: CL:0000558 name: reticulocyte def: "An immature erythrocyte that changes the protein composition of its plasma membrane by exosome formation and extrusion. The types of protein removed differ between species though removal of the transferrin receptor is apparent in mammals and birds." [GOC:add, GOC:tfm, PMID:15946868, PMID:2037622] subset: blood_and_immune_upper_slim +subset: cellxgene_subset xref: BTO:0001173 xref: CALOHA:TS-0864 xref: MESH:D012156 @@ -988,6 +1019,7 @@ relationship: RO:0002104 PR:000016043 ! has plasma membrane part T-cell acute ly id: CL:0000586 name: germ cell def: "The reproductive cell in multicellular organisms." [MESH:D005854] +subset: cellxgene_subset xref: BTO:0000535 xref: NCIT:C12597 xref: VHOG:0001534 @@ -999,6 +1031,7 @@ relationship: capable_of_part_of GO:0009566 ! fertilization id: CL:0000630 name: supporting cell def: "A cell whose primary function is to support other cell types." [FB:ma, GOC:tfm] +subset: cellxgene_subset synonym: "supportive cell" EXACT [] xref: BTO:0002315 is_a: CL:0000000 ! cell @@ -1026,6 +1059,7 @@ id: CL:0000650 name: mesangial cell def: "A cell type that encapsulates the capillaries and venules in the kidney. This cell secretes mesangial matrix that provides the structural support for the capillaries." [GOC:tfm, http://www.copewithcytokines.de/cope.cgi?key=mesangial%20cells] comment: Do all of these cells really develop from some mesenchymal stem cell? +subset: cellxgene_subset synonym: "kidney mesangial cell" EXACT [] xref: BTO:0000853 xref: CALOHA:TS-0617 @@ -1037,6 +1071,7 @@ relationship: develops_from CL:0000134 ! mesenchymal stem cell [Term] id: CL:0000666 name: fenestrated cell +subset: cellxgene_subset synonym: "window cell" EXACT [] is_a: CL:0000066 ! epithelial cell @@ -1045,6 +1080,7 @@ id: CL:0000669 name: pericyte def: "An elongated, contractile cell found wrapped about precapillary arterioles outside the basement membrane. Pericytes are present in capillaries where proper adventitia and muscle layer are missing (thus distingushing this cell type from adventitial cells). They are relatively undifferentiated and may become fibroblasts, macrophages, or smooth muscle cells." [GOC:dsd, GOC:tfm, ISBN:0721662544, MESH:D020286, PMID:16807374, PMID:17986482, PMID:20024907] comment: Pericytes are CD10-positive, CD13-positive, CD31-negative, CD45-negative, CD106-positive, CD117-negative, CD140-positive, CD144-negative, CD146-positive, CD271-positive, CD325-positive, NG2-positive, RGS5-positive, SMA-positive, and desmin-positive. A subpopulation is CD248-positive. They are also capable of producing angiopoietin 1, CXCL12, TGF-beta, and VEGF-A. +subset: cellxgene_subset subset: human_reference_atlas synonym: "adventitial cell" RELATED [] synonym: "adventitial reticular cell" EXACT [] @@ -1064,11 +1100,12 @@ relationship: present_in_taxon NCBITaxon:9606 id: CL:0000680 name: muscle precursor cell def: "A non-terminally differentiated cell that is capable of developing into a muscle cell." [GOC:add] +subset: cellxgene_subset is_a: CL:0000055 ! non-terminally differentiated cell intersection_of: CL:0011115 ! precursor cell -intersection_of: RO:0002203 CL:0000187 ! develops into muscle cell +intersection_of: develops_into CL:0000187 ! muscle cell relationship: develops_from CL:0000222 ! mesodermal cell -relationship: RO:0002203 CL:0000187 ! develops into muscle cell +relationship: develops_into CL:0000187 ! muscle cell [Term] id: CL:0000723 @@ -1085,6 +1122,7 @@ relationship: capable_of GO:0048103 ! somatic stem cell division id: CL:0000763 name: myeloid cell def: "A cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage." [GOC:add] +subset: cellxgene_subset xref: BTO:0001441 xref: CALOHA:TS-0647 xref: MESH:D022423 @@ -1098,6 +1136,7 @@ id: CL:0000764 name: erythroid lineage cell def: "A immature or mature cell in the lineage leading to and including erythrocytes." [GOC:add, GOC:tfm] comment: Note that in FMA erythropoietic cells are types of nucleated erythrocytes and thus don't include erythrocytes. +subset: cellxgene_subset subset: human_reference_atlas synonym: "erythropoietic cell" EXACT [] xref: CALOHA:TS-0290 @@ -1111,6 +1150,7 @@ id: CL:0000765 name: erythroblast def: "A nucleated precursor of an erythrocyte that lacks hematopoietic lineage markers." [GOC:add, ISBN:0721601464, PMID:18174176] subset: blood_and_immune_upper_slim +subset: cellxgene_subset synonym: "normoblast" EXACT [] xref: BTO:0001571 xref: CALOHA:TS-0289 @@ -1155,6 +1195,7 @@ name: hematopoietic multipotent progenitor cell def: "A hematopoietic multipotent progenitor cell is multipotent, but not capable of long-term self-renewal. These cells are characterized as lacking lineage cell surface markers and being CD34-positive in both mice and humans." [GOC:add, GOC:tfm, PMID:19022770] comment: Markers differ between mouse and human. subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "hemopoietic progenitor cell" EXACT [] synonym: "MPP" EXACT [] @@ -1202,6 +1243,7 @@ id: CL:0000839 name: myeloid lineage restricted progenitor cell def: "A progenitor cell restricted to the myeloid lineage." [GOC:add, GOC:tfm, PMID:19022770] comment: Note that this is a class of cell types, not an identified single cell type. +subset: cellxgene_subset subset: human_reference_atlas synonym: "myeloid progenitor cell" BROAD [] xref: BTO:0004730 @@ -1218,6 +1260,7 @@ relationship: present_in_taxon NCBITaxon:9606 id: CL:0000988 name: hematopoietic cell def: "A cell of a hematopoietic lineage." [GO_REF:0000031, GOC:add] +subset: cellxgene_subset synonym: "haematopoietic cell" EXACT [] synonym: "haemopoietic cell" EXACT [] synonym: "hemopoietic cell" EXACT [] @@ -1285,6 +1328,7 @@ id: CL:0002139 name: endothelial cell of vascular tree def: "An endothelial cell of the vascular tree, which includes blood vessels and lymphatic vessels." [GOC:dsd, GOC:tfm, PMID:12768659] comment: These cells are reportedly CD31-positive, CD34-positive, CD144-positive, TAL1-positive. +subset: cellxgene_subset synonym: "cubodial endothelial cell of vascular tree" NARROW [] synonym: "vascular endothelial cell" EXACT [] xref: BTO:0001854 @@ -1316,6 +1360,7 @@ creation_date: 2010-08-25T02:20:55Z id: CL:0002188 name: glomerular endothelial cell def: "An endothelial cell found in the glomerulus of the kidney. This cell is flattened, highly fenestrated, and plays a vital role in the formation of glomerular ultrafiltrate." [GOC:tfm, PMID:15840009] +subset: cellxgene_subset subset: kidney_upper_slim xref: BTO:0004632 xref: FMA:70970 @@ -1358,6 +1403,7 @@ relationship: part_of UBERON:0004135 ! distal tubule id: CL:0002306 name: epithelial cell of proximal tubule def: "An epithelial cell of the proximal tubule of the kidney." [GOC:tfm, ISBN:1-4160-2328-3] +subset: cellxgene_subset subset: human_reference_atlas subset: kidney_upper_slim synonym: "kidney proximal tubule epithelial cell" EXACT [] @@ -1376,6 +1422,7 @@ relationship: present_in_taxon NCBITaxon:9606 id: CL:0002319 name: neural cell def: "A cell that is part of the nervous system." [GOC:tfm, ISBN:0618947256] +subset: cellxgene_subset xref: CALOHA:TS-2040 xref: FMA:70333 is_a: CL:0000000 ! cell @@ -1389,6 +1436,7 @@ creation_date: 2010-09-15T01:34:57Z id: CL:0002320 name: connective tissue cell def: "A cell of the supporting or framework tissue of the body, arising chiefly from the embryonic mesoderm and including adipose tissue, cartilage, and bone." [GOC:tfm, ISBN:0618947256] +subset: cellxgene_subset xref: CALOHA:TS-2096 xref: FMA:63875 xref: MESH:D003239 @@ -1431,6 +1479,7 @@ creation_date: 2010-12-07T09:37:22Z id: CL:0002518 name: kidney epithelial cell def: "An epithelial cell of the kidney." [GOC:tfm, KUPO:SJ] +subset: cellxgene_subset xref: KUPO:0001019 is_a: CL:0000066 ! epithelial cell is_a: CL:1000497 {is_inferred="true"} ! kidney cell @@ -1473,6 +1522,7 @@ creation_date: 2011-10-25T03:49:41Z id: CL:0005009 name: renal principal cell def: "A cuboidal epithelial cell of the kidney which regulates sodium and potassium balance. The activity of sodium and potassium channels on the apical membrane of the cell is regulated by aldosterone and vasopressin. In mammals this cell type is located in the renal collecting duct system." [CL:CVS] +subset: cellxgene_subset is_a: CL:0000075 ! columnar/cuboidal epithelial cell is_a: CL:0002518 ! kidney epithelial cell @@ -1496,6 +1546,7 @@ is_a: CL:0000187 ! muscle cell id: CL:0008001 name: hematopoietic precursor cell def: "Any hematopoietic cell that is a precursor of some other hematopoietic cell type." [GOC:dos] +subset: cellxgene_subset is_a: CL:0000988 ! hematopoietic cell [Term] @@ -1512,6 +1563,7 @@ relationship: part_of UBERON:8600004 ! visceral muscle tissue id: CL:0008019 name: mesenchymal cell def: "A non-polarised cell precursor cell that is part of some mesenchyme, is associated with the cell matrix but is not connected to other cells and is capable of migration." [] +subset: cellxgene_subset subset: human_reference_atlas synonym: "mesenchyme cell" EXACT [] is_a: CL:0000219 ! motile cell @@ -1524,6 +1576,7 @@ id: CL:0008034 name: mural cell def: "Mural cells are pericytes and the vascular smooth muscle cells (vSMCs) of the microcirculation." [Wiki:Mural_cell&oldid=930603194] subset: added_for_HCA +subset: cellxgene_subset subset: human_reference_atlas is_a: CL:4033054 ! perivascular cell relationship: dc-contributor https://orcid.org/0000-0002-7073-9172 @@ -1542,6 +1595,7 @@ relationship: seeAlso https://github.com/obophenotype/cell-ontology/issues/786 id: CL:0011012 name: neural crest cell def: "A cell of the neural crest. Neural crest cells are multipotent. Premigratory neural crest cells are found at the neural plate boarder, some of which will undergo ectomesynchymal transition and delamination to form migratory neural crest cells." [https://orcid.org/0000-0001-5208-3432, https://orcid.org/0000-0002-9900-7880] +subset: cellxgene_subset is_a: CL:0000048 ! multi fate stem cell is_a: CL:0002321 ! embryonic cell (metazoa) @@ -1549,6 +1603,7 @@ is_a: CL:0002321 ! embryonic cell (metazoa) id: CL:0011026 name: progenitor cell def: "A precursor cell that has a tendency to differentiate into a specific type of cell. They are descendants of stem cells, only they are more constrained in their differentiation potential or capacity for self-renewal, and are often more limited in both senses." [https://doi.org/10.1016/B978-0-12-409503-8.00002-0, ISBN:978-1-62808-994-3] +subset: cellxgene_subset is_a: CL:0011115 ! precursor cell intersection_of: CL:0011115 ! precursor cell intersection_of: develops_from CL:0000034 ! stem cell @@ -1560,6 +1615,7 @@ id: CL:0011115 name: precursor cell def: "A cell that, by division or terminal differentiation, can give rise to other cell types." [GOC:dos] comment: Work is needed on GO 'cell differentiation' before it is clear whether the equivalent class definition 'native cell' that capable_of some 'cell differentiation' works. Also, may want to consider merging this with non-terminally differentiated cell. +subset: cellxgene_subset is_a: CL:0000000 ! cell intersection_of: CL:0000000 ! cell intersection_of: capable_of GO:0030154 ! cell differentiation @@ -1599,21 +1655,11 @@ relationship: bearer_of PATO:0070047 ! polychromatophilic relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2009-12-28T04:25:23Z -[Term] -id: CL:0017505 -name: increased nucleus size -def: "A nucleus size quality which is relatively high compared to the amount of cytoplasm present in the same cell." [GOC:tfm] -is_a: GO:0005634 ! nucleus -intersection_of: GO:0005634 ! nucleus -intersection_of: bearer_of PATO:0000586 ! increased size -relationship: bearer_of PATO:0000586 ! increased size -relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 -creation_date: 2009-12-23T10:53:24Z - [Term] id: CL:1000449 name: epithelial cell of nephron def: "An epithelial cell that is part of the nephron." [GOC:tfm] +subset: cellxgene_subset xref: FMA:70965 is_a: CL:0002518 ! kidney epithelial cell intersection_of: CL:0000066 ! epithelial cell @@ -1624,6 +1670,7 @@ relationship: part_of UBERON:0001285 ! nephron id: CL:1000450 name: epithelial cell of glomerular capsule def: "An epithelial cell that is part of the glomerular capsule." [GOC:tfm] +subset: cellxgene_subset subset: kidney_upper_slim synonym: "Bowmans capsule epithelial cell" EXACT [] synonym: "epithelial cell of Bowman's capsule" EXACT [FMA:70966] @@ -1638,6 +1685,7 @@ relationship: part_of UBERON:0001230 ! glomerular capsule id: CL:1000454 name: kidney collecting duct epithelial cell def: "An epithelial cell that is part of the collecting duct of renal tubule." [GOC:tfm] +subset: cellxgene_subset subset: human_reference_atlas subset: kidney_upper_slim synonym: "epithelial cell of renal collecting tubule" EXACT [FMA:70982] @@ -1655,6 +1703,7 @@ id: CL:1000494 name: nephron tubule epithelial cell def: "An epithelial cell that is part of a nephron tubule." [GOC:tfm] comment: This needs to be further defined as a juxtamedullary nephron. Will request the juxtamedullary nephron tubule class from UBERON. +subset: cellxgene_subset synonym: "kidney tubule epithelial cell" EXACT [] xref: FMA:86785 xref: KUPO:0001022 @@ -1668,6 +1717,7 @@ relationship: part_of UBERON:0004810 ! nephron tubule epithelium id: CL:1000497 name: kidney cell def: "A cell that is part of a kidney." [] +subset: cellxgene_subset xref: KUPO:0001010 is_a: CL:0000000 ! cell intersection_of: CL:0000000 ! cell @@ -1678,6 +1728,7 @@ relationship: part_of UBERON:0002113 ! kidney id: CL:1000500 name: kidney interstitial cell def: "A cell that is part of kidney interstitium." [] +subset: cellxgene_subset subset: kidney_upper_slim xref: KUPO:0001013 is_a: CL:1000497 ! kidney cell @@ -1721,6 +1772,7 @@ relationship: part_of UBERON:0001231 ! nephron tubule [Term] id: CL:1000510 name: kidney glomerular epithelial cell +subset: cellxgene_subset xref: KUPO:0001023 is_a: CL:1000746 ! glomerular cell intersection_of: CL:0002518 ! kidney epithelial cell @@ -1763,6 +1815,7 @@ relationship: part_of UBERON:0001229 ! renal corpuscle [Term] id: CL:1000615 name: kidney cortex tubule cell +subset: cellxgene_subset xref: KUPO:0001024 is_a: CL:0002584 ! renal cortical epithelial cell is_a: CL:1000449 ! epithelial cell of nephron @@ -1785,6 +1838,7 @@ relationship: part_of UBERON:0002303 ! juxtaglomerular apparatus [Term] id: CL:1000692 name: kidney interstitial fibroblast +subset: cellxgene_subset subset: human_reference_atlas xref: KUPO:0001102 is_a: CL:0000057 ! fibroblast @@ -1805,6 +1859,7 @@ relationship: part_of UBERON:0000074 ! renal glomerulus [Term] id: CL:1000768 name: kidney connecting tubule epithelial cell +subset: cellxgene_subset subset: human_reference_atlas subset: kidney_upper_slim xref: KUPO:0001058 @@ -1818,6 +1873,7 @@ relationship: present_in_taxon NCBITaxon:9606 [Term] id: CL:1000849 name: kidney distal convoluted tubule epithelial cell +subset: cellxgene_subset subset: human_reference_atlas subset: kidney_upper_slim xref: KUPO:0001056 @@ -1851,6 +1907,7 @@ relationship: part_of UBERON:0003644 ! kidney arterial blood vessel [Term] id: CL:1000892 name: kidney capillary endothelial cell +subset: cellxgene_subset subset: kidney_upper_slim xref: KUPO:0001030 is_a: CL:0000071 ! blood vessel endothelial cell @@ -1872,6 +1929,7 @@ relationship: part_of UBERON:0001140 ! renal vein [Term] id: CL:1000909 name: kidney loop of Henle epithelial cell +subset: cellxgene_subset xref: KUPO:0001047 is_a: CL:1000494 {is_inferred="true"} ! nephron tubule epithelial cell intersection_of: CL:1000494 ! nephron tubule epithelial cell @@ -1881,6 +1939,7 @@ relationship: part_of UBERON:0001288 ! loop of Henle [Term] id: CL:1001016 name: kidney loop of Henle ascending limb epithelial cell +subset: cellxgene_subset subset: kidney_upper_slim xref: KUPO:0001048 is_a: CL:0002305 ! epithelial cell of distal tubule @@ -1903,6 +1962,7 @@ relationship: part_of UBERON:0001289 ! descending limb of loop of Henle id: CL:1001225 name: kidney collecting duct cell def: "A cell that is part of a collecting duct of renal tubule." [] +subset: cellxgene_subset xref: KUPO:0001012 xref: Wikipedia:Kidney_collecting_duct_cell is_a: CL:1000497 ! kidney cell @@ -1914,6 +1974,7 @@ relationship: part_of UBERON:0001232 ! collecting duct of renal tubule id: CL:1001318 name: renal interstitial pericyte def: "A pericyte cell located in the kidney interstitium." [] +subset: cellxgene_subset subset: human_reference_atlas xref: KUPO:0001104 is_a: CL:0000669 {is_inferred="true"} ! pericyte @@ -2375,7 +2436,7 @@ id: GO:0005575 name: cellular_component namespace: cellular_component alt_id: GO:0008372 -def: "A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex)." [GOC:pdt] +def: "A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex)." [GOC:pdt] comment: Note that, in addition to forming the root of the cellular component ontology, this term is recommended for the annotation of gene products whose cellular component is unknown. When this term is used for annotation, it indicates that no information was available about the cellular component of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this. subset: goslim_candida subset: goslim_chembl @@ -2406,8 +2467,8 @@ subset: goslim_metagenomics subset: goslim_mouse subset: goslim_pir subset: goslim_plant +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset synonym: "extracellular" EXACT [] xref: Wikipedia:Extracellular is_a: GO:0110165 ! cellular anatomical entity @@ -2466,7 +2527,7 @@ comment: Note that for multicellular organisms, the extracellular space refers t subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "intercellular space" RELATED [] xref: NIF_Subcellular:sao1425028079 is_a: GO:0110165 ! cellular anatomical entity @@ -2530,8 +2591,8 @@ subset: goslim_flybase_ribbon subset: goslim_generic subset: goslim_metagenomics subset: goslim_pir +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset synonym: "chromatid" RELATED [] synonym: "interphase chromosome" NARROW [] synonym: "prophase chromosome" NARROW [] @@ -2565,8 +2626,8 @@ subset: goslim_chembl subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset xref: Wikipedia:Cytoplasm is_a: GO:0110165 ! cellular anatomical entity relationship: part_of GO:0005622 ! intracellular anatomical structure @@ -2641,8 +2702,8 @@ subset: goslim_generic subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset synonym: "free ribosome" NARROW [NIF_Subcellular:sao1139385046] synonym: "membrane bound ribosome" NARROW [NIF_Subcellular:sao1291545653] synonym: "ribosomal RNA" RELATED [] @@ -2666,8 +2727,8 @@ subset: goslim_generic subset: goslim_mouse subset: goslim_pir subset: goslim_plant +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset xref: Wikipedia:Cytoskeleton is_a: GO:0043232 ! intracellular non-membrane-bounded organelle @@ -2700,8 +2761,8 @@ subset: goslim_generic subset: goslim_metagenomics subset: goslim_mouse subset: goslim_plant +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset synonym: "bacterial inner membrane" NARROW [] synonym: "cell membrane" EXACT [] synonym: "cellular membrane" EXACT [NIF_Subcellular:sao6433132645] @@ -2793,7 +2854,7 @@ subset: goslim_drosophila subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "protein anabolism" EXACT [] synonym: "protein biosynthesis" EXACT [] synonym: "protein biosynthetic process" EXACT [] @@ -2865,7 +2926,7 @@ subset: goslim_chembl subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "single-organism transport" RELATED [] is_a: GO:0051234 ! establishment of localization property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20292" xsd:anyURI @@ -2982,8 +3043,8 @@ subset: goslim_candida subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset synonym: "cytoskeletal organization and biogenesis" RELATED [GOC:mah] synonym: "cytoskeletal regulator activity" RELATED [] synonym: "cytoskeleton organisation" EXACT [] @@ -3306,7 +3367,7 @@ id: GO:0008219 name: cell death namespace: biological_process def: "Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538)." [GOC:mah, GOC:mtg_apoptosis, PMID:25236395] -comment: This term should not be used for direct annotation, it is currently kept in GO as a placeholder for describing cell death phenotypes in uPHENO. When information is provided on a programmed cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'). Unintentional cell death, i.e. cell death caused by injury, ageing, or cell phenotypes observed as a result of a pathological mutation in an essential gene should NOT be annotated using GO terms. +comment: This term should not be used for direct annotation, it is currently kept in GO as a placeholder for describing cell death phenotypes in uPHENO. When information is provided on a programmed cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'). Unintentional cell death, i.e. cell death caused by injury, ageing, or cell phenotypes observed as a result of a pathological mutation in an essential gene should NOT be annotated using GO terms. subset: gocheck_do_not_annotate synonym: "accidental cell death" RELATED [] synonym: "necrosis" RELATED [] @@ -3514,7 +3575,7 @@ subset: goslim_drosophila subset: goslim_generic subset: goslim_mouse subset: goslim_plant -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "caspase-independent apoptosis" RELATED [] synonym: "caspase-independent cell death" NARROW [] synonym: "non-apoptotic programmed cell death" NARROW [] @@ -3871,8 +3932,8 @@ subset: goslim_flybase_ribbon subset: goslim_generic subset: goslim_mouse subset: goslim_pombe +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset synonym: "biological signaling" EXACT [] synonym: "signaling process" EXACT [] synonym: "signalling" EXACT [] @@ -3899,7 +3960,7 @@ id: GO:0030030 name: cell projection organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon." [GOC:jl, GOC:mah, http://www.cogsci.princeton.edu/~wn/] -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "cell projection organisation" EXACT [] synonym: "cell projection organization and biogenesis" RELATED [GOC:mah] synonym: "cell surface structure organization and biogenesis" RELATED [GOC:mah] @@ -4085,7 +4146,7 @@ subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_pir -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "matrisome" NARROW [] synonym: "proteinaceous extracellular matrix" EXACT [] xref: NIF_Subcellular:nlx_subcell_20090513 @@ -4539,7 +4600,7 @@ subset: goslim_agr subset: goslim_flybase_ribbon subset: goslim_mouse subset: goslim_pir -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "cell process" BROAD [] synonym: "cellular process" BROAD [] synonym: "cellular projection" EXACT [] @@ -4574,12 +4635,14 @@ alt_id: GO:0034960 alt_id: GO:0043283 alt_id: GO:0044259 def: "The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:mah] +subset: gocheck_do_not_annotate subset: goslim_pir synonym: "biopolymer metabolic process" EXACT [GOC:mtg_chebi_dec09] synonym: "macromolecule metabolism" EXACT [] synonym: "multicellular organismal macromolecule metabolic process" NARROW [] synonym: "organismal macromolecule metabolism" EXACT [] is_a: GO:0008152 ! metabolic process +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI [Term] id: GO:0043226 @@ -4589,7 +4652,7 @@ def: "Organized structure of distinctive morphology and function. Includes the n subset: goslim_chembl subset: goslim_generic subset: goslim_pir -subset: prokaryote_subset +subset: goslim_prokaryote xref: NIF_Subcellular:sao1539965131 xref: Wikipedia:Organelle is_a: GO:0110165 ! cellular anatomical entity @@ -4751,9 +4814,11 @@ id: GO:0044238 name: primary metabolic process namespace: biological_process def: "The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism." [GOC:go_curators, http://www.metacyc.org] +subset: gocheck_do_not_annotate subset: goslim_pir synonym: "primary metabolism" EXACT [] is_a: GO:0008152 ! metabolic process +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI [Term] id: GO:0044249 @@ -5001,6 +5066,7 @@ id: GO:0048856 name: anatomical structure development namespace: biological_process def: "The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome." [GO_REF:0000021] +subset: gocheck_do_not_annotate subset: goslim_chembl subset: goslim_generic subset: goslim_plant @@ -5009,6 +5075,7 @@ is_a: GO:0032502 ! developmental process intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of UBERON:0000061 ! anatomical structure relationship: results_in_development_of UBERON:0000061 ! anatomical structure +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI [Term] id: GO:0048869 @@ -5026,7 +5093,7 @@ def: "Any process involved in the controlled self-propelled movement of a cell t subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "cell locomotion" EXACT [] synonym: "cell movement" RELATED [] synonym: "movement of a cell" EXACT [] @@ -5141,7 +5208,7 @@ subset: goslim_agr subset: goslim_flybase_ribbon subset: goslim_mouse subset: goslim_pir -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "physiological response to stimulus" EXACT [] is_a: GO:0008150 ! biological_process @@ -5469,7 +5536,7 @@ subset: goslim_generic subset: goslim_metagenomics subset: goslim_pir subset: goslim_pombe -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "cellular macromolecule complex assembly" RELATED [] synonym: "cellular protein complex assembly" EXACT [] synonym: "cellular protein-containing complex assembly" RELATED [] @@ -5616,10 +5683,12 @@ id: GO:0071704 name: organic substance metabolic process namespace: biological_process def: "The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon." [GOC:mah] +subset: gocheck_do_not_annotate synonym: "organic molecular entity metabolic process" EXACT [] synonym: "organic molecular entity metabolism" EXACT [] synonym: "organic substance metabolism" EXACT [] is_a: GO:0008152 ! metabolic process +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI created_by: mah creation_date: 2010-03-08T03:32:18Z @@ -5659,7 +5728,7 @@ creation_date: 2010-09-10T01:39:16Z id: GO:0071944 name: cell periphery namespace: cellular_component -def: "The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures." [GOC:pdt] +def: "The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures." [GOC:pdt] subset: goslim_flybase_ribbon is_a: GO:0110165 ! cellular anatomical entity created_by: mah @@ -6017,6 +6086,7 @@ subset: goslim_pir is_a: GO:0005575 ! cellular_component is_a: UBERON:0000061 ! anatomical structure property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24200" xsd:anyURI +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI created_by: kmv creation_date: 2019-08-12T18:01:37Z @@ -6542,30 +6612,6 @@ subset: attribute_slim synonym: "relational shape quality" EXACT [] is_a: PATO:0000051 ! morphology -[Term] -id: PATO:0000068 -name: qualitative -namespace: quality -comment: TODO: define this or obsolete it and move children somewhere else. -is_a: PATO:0000001 ! quality - -[Term] -id: PATO:0000069 -name: deviation (from_normal) -namespace: quality -def: "A quality inhering in a bearer by virtue of the whether the bearer differs from normal or average." [PATOC:GVG] -subset: attribute_slim -is_a: PATO:0000068 ! qualitative - -[Term] -id: PATO:0000117 -name: size -namespace: quality -def: "A morphology quality inhering in a bearer by virtue of the bearer's physical magnitude." [WordNet:WordNet] -subset: attribute_slim -subset: scalar_slim -is_a: PATO:0000051 ! morphology - [Term] id: PATO:0000141 name: structure @@ -6602,36 +6648,6 @@ synonym: "round" RELATED [] synonym: "rounded" RELATED [] is_a: PATO:0000947 ! elliptic -[Term] -id: PATO:0000461 -name: normal -namespace: quality -def: "A quality inhering in a bearer by virtue of the bearer's exhibiting no deviation from normal or average." [PATOC:GVG] -subset: abnormal_slim -subset: mpath_slim -subset: value_slim -synonym: "average" RELATED [] -is_a: PATO:0000068 ! qualitative -property_value: RO:0002604 PATO:0000460 - -[Term] -id: PATO:0000586 -name: increased size -namespace: quality -alt_id: PATO:0001202 -def: "A size quality which is relatively high." [PATOC:GVG] -subset: value_slim -synonym: "big" RELATED [] -synonym: "enlarged" RELATED [] -synonym: "expanded" RELATED [] -synonym: "great" RELATED [] -synonym: "large" RELATED [] -is_a: PATO:0000117 ! size -is_a: PATO:0002305 ! increased object quality -intersection_of: PATO:0000117 ! size -intersection_of: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal -property_value: RO:0002604 PATO:0000587 - [Term] id: PATO:0000947 name: elliptic @@ -6981,32 +6997,6 @@ is_a: PATO:0002078 ! hollow relationship: dc-contributor https://orcid.org/0000-0002-2061-091X creation_date: 2011-06-08T06:33:50Z -[Term] -id: PATO:0002300 -name: increased quality -namespace: quality -def: "A quality that has a value that is increased compared to normal or average." [PATOC:GVG] -is_a: PATO:0000069 ! deviation (from_normal) -intersection_of: PATO:0000001 ! quality -intersection_of: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal -relationship: dc-contributor https://orcid.org/0000-0002-2061-091X -relationship: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal -property_value: RO:0002604 PATO:0002301 -creation_date: 2011-06-16T06:39:43Z - -[Term] -id: PATO:0002305 -name: increased object quality -namespace: quality -def: "A quality of an object that has a value that is increased compared to normal or average." [PATOC:GVG] -is_a: PATO:0001241 ! physical object quality -is_a: PATO:0002300 ! increased quality -intersection_of: PATO:0001241 ! physical object quality -intersection_of: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal -relationship: dc-contributor https://orcid.org/0000-0002-2061-091X -property_value: RO:0002604 PATO:0002303 -creation_date: 2011-06-16T06:54:01Z - [Term] id: PATO:0002309 name: fiber shaped @@ -7088,6 +7078,16 @@ def: "A quality inhering in a bearer by virtue of the extent to which the bearer subset: attribute_slim is_a: PATO:0000141 ! structure +[Term] +id: PATO:0040072 +name: high nuclear/cytoplasmic ratio +namespace: quality +def: "A quality inhering in a cell by virtue of the cell having a high nuclear/cytoplasmic ratio." [http://lymerick.net/blood-cells.pdf, Wikipedia:NC_ratio&oldid=931936284] +comment: A high nuclear/cytolasmic ratio is 70% or higher. +synonym: "high N:C ratio" EXACT [] +is_a: PATO:0001396 ! cellular quality +created_by: http://orcid.org/0000-0001-5208-3432 + [Term] id: PATO:0070044 name: anatomical structure quality @@ -7594,7 +7594,7 @@ xref: EFO:0000799 xref: EHDAA2:0003193 xref: EMAPA:37283 {source="MA:th"} xref: EV:0100155 -xref: FBbt:00007000 +xref: FBbt:00007000 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: HAO:0000144 xref: MAT:0000023 xref: MESH:D005121 @@ -7728,7 +7728,7 @@ synonym: "ducts" RELATED OMO:0003004 [XAO:0004000] synonym: "exocrine duct" NARROW [] synonym: "exocrine gland duct" NARROW [] xref: AAO:0011123 -xref: FBbt:00100314 +xref: FBbt:00100314 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:30320 xref: galen:Duct xref: NCIT:C12948 @@ -7779,7 +7779,7 @@ xref: BILA:0000003 xref: CARO:0000003 xref: EHDAA2:0003003 xref: EMAPA:0 -xref: FBbt:00007001 +xref: FBbt:00007001 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:305751 xref: FMA:67135 xref: GAID:781 @@ -7950,7 +7950,7 @@ subset: vertebrate_core synonym: "glomerular capillary tuft" RELATED [ZFA:0001288] synonym: "glomerular tuft" RELATED INCONSISTENT [] synonym: "glomerulus" BROAD [] -synonym: "glomerulus renis" RELATED LATIN [Wikipedia:Glomerulus] +synonym: "glomerulus renis" RELATED OMO:0003011 [Wikipedia:Glomerulus] synonym: "Malphigian glomerulus" RELATED MISSPELLING [BTO:0000530] synonym: "Malpighian glomerulus" RELATED [http://medical-dictionary.thefreedictionary.com/malpighian+glomerulus] synonym: "Malpighian tuft" RELATED [http://medical-dictionary.thefreedictionary.com/malpighian+glomerulus] @@ -8092,7 +8092,7 @@ name: mesonephric tubule namespace: uberon def: "A mesonephric tubule is an epithelial tube that is part of the mesonephros[GO]. Genital ridge that is next to the mesonephros[WP]." [Wikipedia:Mesonephric_tubules] synonym: "renal tubules" RELATED OMO:0003004 [VHOG:0000500] -synonym: "tubuli mesonephrici" RELATED LATIN [Wikipedia:Mesonephric_tubules] +synonym: "tubuli mesonephrici" RELATED OMO:0003011 [Wikipedia:Mesonephric_tubules] xref: AAO:0010389 xref: EHDAA2:0001134 xref: EMAPA:16747 @@ -8115,8 +8115,8 @@ namespace: uberon def: "An epithelial swelling on the Wolffian duct that elongates to invade the adjacent metanephric mesenchyme[MP]." [MP:0010979, PMID:19828308] subset: pheno_slim synonym: "diverticulum" RELATED [BTO:0001646] -synonym: "diverticulum metanephricum" RELATED LATIN [Wikipedia:Ureteric_bud] -synonym: "gemma ureterica" RELATED LATIN [Wikipedia:Ureteric_bud] +synonym: "diverticulum metanephricum" RELATED OMO:0003011 [Wikipedia:Ureteric_bud] +synonym: "gemma ureterica" RELATED OMO:0003011 [Wikipedia:Ureteric_bud] synonym: "metanephric bud" RELATED [BTO:0001646] synonym: "metanephric diverticulum" RELATED [Wikipedia:Metanephros#Metanephros] synonym: "ureteric ampulla" RELATED [] @@ -8234,13 +8234,13 @@ synonym: "fertilized egg stage" RELATED [] synonym: "one cell stage" EXACT [] synonym: "one-cell stage" RELATED [VHOG:0000745] synonym: "zygote" RELATED [VHOG:0000745] -synonym: "zygotum" RELATED LATIN [Wikipedia:Zygote] +synonym: "zygotum" RELATED OMO:0003011 [Wikipedia:Zygote] xref: BilaDO:0000005 xref: BILS:0000106 xref: EFO:0001322 xref: EHDAA:27 xref: FBdv:00005288 -xref: IDOMAL:0000302 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: IDOMAL:0000302 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: NCIT:C12601 xref: PdumDv:0000100 xref: VHOG:0000745 @@ -8482,7 +8482,7 @@ namespace: uberon def: "The ventral part of the cloaca remaining after septation of the rectum, which further develops into part of the bladder, part of the prostatic part of the male urethra and the urethra and vestibule in females." [ISBN:0-683-40008-8, MP:0010116] subset: pheno_slim synonym: "fetal UGS" EXACT [PMID:18977204] -synonym: "sinus urogenitalis" EXACT LATIN [] +synonym: "sinus urogenitalis" EXACT OMO:0003011 [] synonym: "UGS" EXACT [MP:0010116] synonym: "urogenital sinus" BROAD [MP:0010116] xref: EHDAA2:0004060 @@ -8515,13 +8515,13 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "adult mouth" NARROW [] -synonym: "cavital oralis" RELATED LATIN [Wikipedia:Mouth] +synonym: "cavital oralis" RELATED OMO:0003011 [Wikipedia:Mouth] synonym: "cavitas oris" RELATED [BTO:0001090] synonym: "cavum oris" RELATED [BTO:0001090] synonym: "mouth cavity" RELATED [BTO:0001090] synonym: "oral region" RELATED [EHDAA2:0001326] synonym: "oral vestibule" RELATED [BTO:0001090] -synonym: "regio oralis" EXACT LATIN [BTO:0004698, FMA:49184, FMA:TA] +synonym: "regio oralis" EXACT OMO:0003011 [BTO:0004698, FMA:49184, FMA:TA] synonym: "rima oris" RELATED [BTO:0001090] synonym: "stoma" RELATED [] synonym: "stomatodaeum" RELATED [VHOG:0000812] @@ -8536,7 +8536,7 @@ xref: EFO:0000825 xref: EHDAA2:0001326 xref: EHDAA:542 xref: EMAPA:16262 -xref: FBbt:00003126 +xref: FBbt:00003126 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:49184 xref: GAID:75 xref: galen:Mouth @@ -8686,7 +8686,8 @@ id: UBERON:0000353 name: parenchyma namespace: uberon def: "Functional part of an organ in the body. This is in contrast to the stroma, which refers to the structural tissue of organs, being exactly, connective tissues." [Wikipedia:Parenchyma] -xref: BTO:0001539 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: BTO:0000999 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} +xref: BTO:0001539 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: EHDAA:3015 xref: EHDAA:3905 xref: EHDAA:3999 @@ -8721,9 +8722,9 @@ subset: human_reference_atlas subset: pheno_slim synonym: "kidney medulla" EXACT [OBOL:automatic] synonym: "medulla of kidney" EXACT [OBOL:automatic] -synonym: "medulla renalis" EXACT LATIN [FMA:74268, FMA:TA] +synonym: "medulla renalis" EXACT OMO:0003011 [FMA:74268, FMA:TA] synonym: "medullary pyramids" RELATED OMO:0003004 [FMA:74268] -synonym: "pyramides renales" EXACT LATIN [FMA:74268, FMA:TA] +synonym: "pyramides renales" EXACT OMO:0003011 [FMA:74268, FMA:TA] synonym: "renal marrow" RELATED [BTO:0001167] synonym: "renal medullae" EXACT OMO:0003004 [FMA:86327] synonym: "renal medullae set" EXACT OMO:0003004 [FMA:86327] @@ -8815,7 +8816,7 @@ xref: CALOHA:TS-2101 xref: CARO:0000004 xref: EHDAA2:0003004 xref: EMAPA:35178 -xref: FBbt:00007019 +xref: FBbt:00007019 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:9669 xref: galen:BodySubstance xref: HAO:0000004 @@ -8850,7 +8851,7 @@ xref: AEO:0000005 xref: BILA:0000005 xref: CARO:0000005 xref: EHDAA2:0003005 -xref: FBbt:00007017 +xref: FBbt:00007017 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:5897 xref: HAO:0000005 xref: NCIT:C94478 @@ -8878,7 +8879,7 @@ xref: AEO:0000006 xref: BILA:0000006 xref: CARO:0000006 xref: EHDAA2:0003006 -xref: FBbt:00007016 +xref: FBbt:00007016 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:67165 xref: HAO:0000006 xref: TAO:0001836 @@ -8904,7 +8905,7 @@ xref: AEO:0000007 xref: BILA:0000007 xref: CARO:0000007 xref: EHDAA2:0003007 -xref: FBbt:00007015 +xref: FBbt:00007015 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:67112 xref: HAO:0000007 xref: TAO:0001835 @@ -8942,11 +8943,11 @@ xref: EHDAA2:0003011 xref: EHDAA:392 xref: EMAPA:16103 xref: EV:0100000 -xref: FBbt:00004856 +xref: FBbt:00004856 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:7149 xref: galen:AnatomicalSystem xref: HAO:0000011 -xref: IDOMAL:0002460 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: IDOMAL:0002460 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: MA:0000003 xref: NCIT:C12919 xref: SCTID:278195005 @@ -8997,7 +8998,7 @@ xref: EHDAA2:0003191 xref: EHDAA:1 xref: EMAPA:25765 xref: EV:0100016 -xref: FBbt:00000001 +xref: FBbt:00000001 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:256135 xref: galen:Organism xref: HAO:0000012 @@ -9063,7 +9064,7 @@ xref: CARO:0000032 xref: EFO:0000808 xref: EHDAA2:0003032 xref: EMAPA:36031 -xref: FBbt:00007009 +xref: FBbt:00007009 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:7153 xref: galen:BodyPart xref: HAO:0000032 @@ -9099,7 +9100,7 @@ xref: AEO:0000040 xref: BILA:0000040 xref: CARO:0000040 xref: EHDAA2:0003040 -xref: FBbt:00007013 +xref: FBbt:00007013 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:63863 xref: HAO:0000040 xref: TAO:0000382 @@ -9119,8 +9120,7 @@ namespace: uberon def: "Anatomical group whose component anatomical structures lie in close proximity to each other." [FBbt:00007277] subset: common_anatomy subset: upper_level -xref: FBbt:00007277 -xref: IDOMAL:0002461 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: FBbt:00007277 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: VHOG:0001737 is_a: UBERON:0034923 ! disconnected anatomical group relationship: present_in_taxon NCBITaxon:33090 @@ -9147,7 +9147,7 @@ xref: CALOHA:TS-2090 xref: CARO:0000043 xref: EHDAA2:0003043 xref: EMAPA:35868 -xref: FBbt:00007003 +xref: FBbt:00007003 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:9637 xref: galen:Tissue xref: HAO:0000043 @@ -9182,7 +9182,7 @@ xref: AEO:0000055 xref: BILA:0000055 xref: CARO:0000055 xref: EHDAA2:0003055 -xref: FBbt:00007010 +xref: FBbt:00007010 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: HAO:0000055 xref: TAO:0001488 xref: TGMA:0001847 @@ -9215,7 +9215,7 @@ xref: CALOHA:TS-0288 xref: CARO:0000066 xref: EHDAA2:0003066 xref: EMAPA:32738 -xref: FBbt:00007005 +xref: FBbt:00007005 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:9639 xref: GAID:402 xref: HAO:0000066 @@ -9258,7 +9258,7 @@ xref: AEO:0000068 xref: BILA:0000068 xref: CARO:0000068 xref: EHDAA2_RETIRED:0003068 -xref: FBbt:00007027 +xref: FBbt:00007027 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:45567 xref: HAO:0000068 xref: NCIT:C33552 @@ -9437,11 +9437,11 @@ xref: EHDAA2:0000002 xref: EHDAA2_RETIRED:0003236 xref: EHDAA:38 xref: EMAPA:16039 -xref: FBbt:00000052 +xref: FBbt:00000052 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:69068 xref: GAID:963 xref: http://neurolex.org/wiki/Category\:Embryonic_organism -xref: IDOMAL:0000646 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: IDOMAL:0000646 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: MAT:0000226 xref: MESH:D004622 xref: MIAA:0000019 @@ -9481,7 +9481,7 @@ xref: AAO:0000480 xref: BILA:0000035 xref: BTO:0000556 xref: EMAPA:36033 -xref: FBbt:00000110 +xref: FBbt:00000110 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:69069 xref: GAID:1303 xref: MESH:D005855 @@ -9516,7 +9516,7 @@ xref: EFO:0000414 xref: EHDAA2:0000428 xref: EMAPA:16069 xref: EV:0100003 -xref: FBbt:00000111 +xref: FBbt:00000111 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:69070 xref: GAID:1304 xref: MAT:0000155 @@ -9557,7 +9557,7 @@ xref: EFO:0002545 xref: EHDAA2:0000436 xref: EMAPA:16062 xref: EV:0100005 -xref: FBbt:00000125 +xref: FBbt:00000125 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:69071 xref: GAID:1305 xref: MAT:0000175 @@ -9603,7 +9603,7 @@ xref: EHDAA:160 xref: EHDAA:183 xref: EMAPA:16083 xref: EV:0100006 -xref: FBbt:00000126 +xref: FBbt:00000126 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:69072 xref: GAID:522 xref: MAT:0000174 @@ -9647,7 +9647,7 @@ synonym: "stomodeal-hypophyseal primordium" BROAD [XAO:0000269] xref: BTO:0004224 xref: EHDAA2:0001929 xref: EMAPA:16263 -xref: FBbt:00000439 +xref: FBbt:00000439 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:295846 xref: NCIT:C34306 xref: TAO:0001290 @@ -9681,7 +9681,7 @@ synonym: "proctodaeum" EXACT [] xref: AAO:0011087 xref: EHDAA2:0000121 xref: EMAPA:25038 -xref: FBbt:00000123 +xref: FBbt:00000123 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: NCIT:C34278 xref: TAO:0000066 xref: UMLS:C0231054 {source="ncithesaurus:Proctodeum"} @@ -9847,6 +9847,7 @@ namespace: uberon def: "Anatomical system that has as its parts the organs concerned with reproduction." [Wikipedia:Reproductive_system] subset: efo_slim subset: functional_classification +subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core @@ -9858,7 +9859,7 @@ synonym: "Geschlechtsorgan" RELATED [BTO:0000081] synonym: "organa genitalia" RELATED [BTO:0000081] synonym: "reproductive tissue" RELATED [BTO:0000081] synonym: "reproductive tract" RELATED [] -synonym: "systemata genitalia" RELATED LATIN [Wikipedia:Reproductive_system] +synonym: "systemata genitalia" RELATED OMO:0003011 [Wikipedia:Reproductive_system] xref: AAO:0010258 xref: BILA:0000103 xref: BTO:0000081 @@ -9868,12 +9869,13 @@ xref: EHDAA2:0001603 xref: EHDAA:5923 xref: EMAPA:17381 xref: EV:0100100 -xref: FBbt:00004857 +xref: FBbt:00004857 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:7160 xref: GAID:363 xref: HAO:0000374 xref: HAO:0000895 xref: MA:0000326 +xref: MESH:D005835 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} xref: MIAA:0000305 xref: NCIT:C12841 xref: SCTID:278875001 @@ -9897,6 +9899,7 @@ disjoint_from: UBERON:8450002 ! excretory system relationship: capable_of_part_of GO:0000003 ! reproduction relationship: existence_ends_during UBERON:0000066 ! fully formed stage relationship: has_part UBERON:0000991 ! gonad +relationship: present_in_taxon NCBITaxon:9606 property_value: dcterms-date "2022-06-10T18:22:34Z" xsd:dateTime property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/5/52/Penis.svg" xsd:anyURI property_value: editor_note "consider splitting genitalia from reproductive system" xsd:string @@ -9921,7 +9924,7 @@ xref: BILA:0000123 xref: BSA:0000079 xref: BTO:0000534 xref: EMAPA:17383 -xref: FBbt:00004858 +xref: FBbt:00004858 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:18250 xref: GAID:368 xref: HAO:0000379 @@ -9968,7 +9971,7 @@ xref: BTO:0000058 xref: CALOHA:TS-1293 xref: EFO:0000793 xref: EV:0100056 -xref: FBbt:00005055 +xref: FBbt:00005055 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:7152 xref: GAID:278 xref: galen:DigestiveSystem @@ -10028,7 +10031,7 @@ xref: EHDAA2:0001601 xref: EHDAA:5901 xref: EMAPA:17366 xref: EV:0100095 -xref: FBbt:00005056 +xref: FBbt:00005056 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:7159 xref: GAID:391 xref: galen:UrinaryTract @@ -10067,9 +10070,10 @@ namespace: uberon def: "Organ system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis[WP]." [Wikipedia:Circulatory_system] subset: human_reference_atlas subset: uberon_slim -synonym: "systema cardiovasculare" RELATED LATIN [Wikipedia:Circulatory_system] +synonym: "systema cardiovasculare" RELATED OMO:0003011 [Wikipedia:Circulatory_system] xref: AAO:0000959 xref: CALOHA:TS-2103 +xref: MESH:D002319 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} xref: VHOG:0001248 xref: Wikipedia:Circulatory_system is_a: UBERON:0000467 ! anatomical system @@ -10106,7 +10110,7 @@ synonym: "muscles" RELATED [] synonym: "muscles set" EXACT [] synonym: "musculature" EXACT [] synonym: "musculature system" RELATED [] -synonym: "musculi" EXACT LATIN [FMA:32558, FMA:TA] +synonym: "musculi" EXACT OMO:0003011 [FMA:32558, FMA:TA] synonym: "set of muscles" EXACT [FMA:32558] synonym: "set of skeletal muscles" EXACT [MA:0000165] xref: AAO:0011066 @@ -10137,12 +10141,13 @@ namespace: uberon def: "The nervous system is an organ system containing predominantly neuron and glial cells. In bilaterally symmetrical organism, it is arranged in a network of tree-like structures connected to a central body. The main functions of the nervous system are to regulate and control body functions, and to receive sensory input, process this information, and generate behavior [CUMBO]." [BIRNLEX:844, ISBN:0-14-051288-8, ISBN:3110148986, NLM:nervous+system, WB:rynl, Wikipedia:Nervous_system, ZFIN:curator] subset: cumbo subset: efo_slim +subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "nerve net" NARROW [Wikipedia:Nerve_net] synonym: "neurological system" EXACT [GO:0050877] -synonym: "systema nervosum" RELATED LATIN [Wikipedia:Nervous_system] +synonym: "systema nervosum" RELATED OMO:0003011 [Wikipedia:Nervous_system] xref: AAO:0000324 xref: BILA:0000079 xref: BIRNLEX:844 @@ -10153,7 +10158,7 @@ xref: EHDAA2:0001246 xref: EHDAA:826 xref: EMAPA:16469 xref: EV:0100162 -xref: FBbt:00005093 +xref: FBbt:00005093 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:7157 xref: GAID:466 xref: MA:0000016 @@ -10182,6 +10187,7 @@ relationship: has_part CL:0000540 ! neuron relationship: immediate_transformation_of UBERON:0016880 {source="Bgee:AN"} ! future nervous system relationship: never_in_taxon NCBITaxon:6040 relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa +relationship: present_in_taxon NCBITaxon:9606 property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/b/b2/TE-Nervous_system_diagram.svg" xsd:anyURI property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/b/ba/Nervous_system_diagram.png" xsd:anyURI property_value: UBPROP:0000001 "A regulatory system of the body that consists of neurons and neuroglial cells. The nervous system is divided into two parts, the central nervous system (CNS) and the peripheral nervous system (PNS). (Source: BioGlossary, www.Biology-Text.com)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000396", ontology="TAO", source="ZFIN:curator"} @@ -10197,13 +10203,14 @@ namespace: uberon def: "The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the neural tube derivatives: the brain and spinal cord. In invertebrates it includes central ganglia plus nerve cord." [GO:0021551, http://www.frontiersinzoology.com/content/7/1/29, https://sourceforge.net/p/geneontology/ontology-requests/11422/] subset: cumbo subset: efo_slim +subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "cerebrospinal axis" NARROW [FMA:55675] synonym: "CNS" EXACT OMO:0003000 [] synonym: "neuraxis" RELATED [FMA:55675] -synonym: "systema nervosum centrale" EXACT LATIN [FMA:55675, FMA:TA] +synonym: "systema nervosum centrale" EXACT OMO:0003011 [FMA:55675, FMA:TA] xref: AAO:0000090 xref: BAMS:CNS xref: BILA:0000080 @@ -10216,7 +10223,7 @@ xref: EHDAA:828 xref: EMAPA:16470 xref: EMAPA:16754 xref: EV:0100163 -xref: FBbt:00005094 +xref: FBbt:00005094 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:55675 xref: GAID:570 xref: MA:0000167 @@ -10237,6 +10244,7 @@ relationship: immediate_transformation_of UBERON:0016879 {source="Bgee:AN"} ! fu relationship: never_in_taxon NCBITaxon:147099 {source="Wikipedia:Acoelomorpha"} relationship: only_in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of UBERON:0001016 ! nervous system +relationship: present_in_taxon NCBITaxon:9606 property_value: UBPROP:0000001 "Part of the nervous system which includes the brain and spinal cord.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000090", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000001 "The brain and spinal cord. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000012", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "The central nervous system (CNS) is the part of the nervous system which includes the brain, spinal cord, and nerve cell layer of the retina (CUMBO)." xsd:string {source="BIRNLEX:1099"} @@ -10250,15 +10258,15 @@ def: "Anterior subdivision of a digestive tract." [http://orcid.org/0000-0002-66 subset: developmental_classification subset: pheno_slim subset: uberon_slim -synonym: "praeenteron" RELATED LATIN [Wikipedia:Foregut] -synonym: "proenteron" RELATED LATIN [Wikipedia:Foregut] +synonym: "praeenteron" RELATED OMO:0003011 [Wikipedia:Foregut] +synonym: "proenteron" RELATED OMO:0003011 [Wikipedia:Foregut] xref: AAO:0011042 xref: BILA:0000085 xref: BTO:0000507 xref: EHDAA2:0000557 xref: EHDAA:520 xref: EMAPA:16548 -xref: FBbt:00005379 +xref: FBbt:00005379 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:45616 xref: MA:0001526 xref: NCIT:C34180 @@ -10283,14 +10291,14 @@ subset: developmental_classification subset: efo_slim subset: pheno_slim subset: uberon_slim -synonym: "mesenteron" RELATED LATIN [Wikipedia:Midgut] +synonym: "mesenteron" RELATED OMO:0003011 [Wikipedia:Midgut] xref: BILA:0000086 xref: BTO:0000863 xref: EFO:0001950 xref: EHDAA2:0001185 xref: EHDAA:983 xref: EMAPA:16255 -xref: FBbt:00005383 +xref: FBbt:00005383 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:45617 xref: MA:0001564 xref: NCIT:C34210 @@ -10316,14 +10324,14 @@ def: "The caudalmost subdivision of a digestive tract." [http://orcid.org/0000-0 subset: developmental_classification subset: pheno_slim subset: uberon_slim -synonym: "metenteron" RELATED LATIN [Wikipedia:Hindgut] +synonym: "metenteron" RELATED OMO:0003011 [Wikipedia:Hindgut] xref: AAO:0011052 xref: BILA:0000087 xref: BTO:0000510 xref: EHDAA2:0000779 xref: EHDAA:975 xref: EMAPA:16715 -xref: FBbt:00005384 +xref: FBbt:00005384 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:45618 xref: MA:0001527 xref: NCIT:C34188 @@ -10359,7 +10367,7 @@ xref: AEO:0000171 xref: BTO:0001886 xref: EFO:0001652 xref: EHDAA2:0003171 -xref: FBbt:00005495 +xref: FBbt:00005495 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:86589 xref: MAT:0000482 xref: NCIT:C34275 @@ -10379,7 +10387,7 @@ subset: uberon_slim subset: vertebrate_core synonym: "neural primordium" RELATED [] synonym: "presumptive central nervous system" RELATED [] -synonym: "tubus neuralis" RELATED LATIN [Wikipedia:Neural_tube] +synonym: "tubus neuralis" RELATED OMO:0003011 [Wikipedia:Neural_tube] xref: AAO:0010617 xref: BTO:0001057 xref: CALOHA:TS-2371 @@ -10391,7 +10399,7 @@ xref: EMAPA:16164 xref: EMAPA:16757 xref: FMA:293882 xref: MAT:0000069 -xref: MESH:D054259 +xref: MESH:D054259 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: MIAA:0000069 xref: NCIT:C34226 xref: neuronames:1365 @@ -10427,7 +10435,7 @@ xref: BILA:0000000 xref: BIRNLEX:6 xref: CARO:0000000 xref: EHDAA2:0002229 -xref: FBbt:10000000 +xref: FBbt:10000000 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:62955 xref: HAO:0000000 xref: MA:0000001 @@ -10455,7 +10463,7 @@ synonym: "inferior caval vein" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "inferior vena cava" EXACT [Wikipedia:Venae_cavae] synonym: "postcava" RELATED [] synonym: "posterior vena cava" EXACT [Wikipedia:Venae_cavae] -synonym: "vena cava inferior" RELATED LATIN [BTO:0002682, Wikipedia:Inferior_vena_cava] +synonym: "vena cava inferior" RELATED OMO:0003011 [BTO:0002682, Wikipedia:Inferior_vena_cava] xref: AAO:0011083 xref: BTO:0002682 xref: EHDAA2:0000611 @@ -10521,7 +10529,7 @@ subset: uberon_slim synonym: "kidney vein" EXACT [OBOL:automatic] synonym: "renal venous tree" EXACT [] synonym: "vein of kidney" EXACT [OBOL:automatic] -synonym: "venae renales" RELATED LATIN [Wikipedia:Renal_vein] +synonym: "venae renales" RELATED OMO:0003011 [Wikipedia:Renal_vein] xref: BTO:0002681 xref: EHDAA2:0001602 xref: EHDAA:8722 @@ -10557,7 +10565,7 @@ subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "kidney pelvis" EXACT [] -synonym: "p. renallis" RELATED LATIN [Wikipedia:Renal_pelvis] +synonym: "p. renallis" RELATED OMO:0003011 [Wikipedia:Renal_pelvis] synonym: "pelvis of ureter" EXACT [] synonym: "pyelum" RELATED [MP:0004194] xref: CALOHA:TS-2230 @@ -10592,7 +10600,7 @@ def: "Outer cortical portion of the kidney, between the renal capsule and the re subset: human_reference_atlas subset: pheno_slim subset: uberon_slim -synonym: "cortex renalis" EXACT LATIN [FMA:15581, FMA:TA] +synonym: "cortex renalis" EXACT OMO:0003011 [FMA:15581, FMA:TA] synonym: "kidney cortex" EXACT [] synonym: "renal cortex" EXACT [] xref: BTO:0001166 @@ -10630,8 +10638,8 @@ subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "corpusculum renale" EXACT LATIN [] -synonym: "corpusculum renis" RELATED LATIN [Wikipedia:Renal_corpuscle] +synonym: "corpusculum renale" EXACT OMO:0003011 [] +synonym: "corpusculum renis" RELATED OMO:0003011 [Wikipedia:Renal_corpuscle] synonym: "cortical renal corpuscle" RELATED [MA:0000376] synonym: "kidney corpuscle" RELATED [Wikipedia:Renal_corpuscle] synonym: "Malphigian corpuscle" EXACT MISSPELLING [MA:0000376] @@ -10672,8 +10680,8 @@ subset: vertebrate_core synonym: "Bowman's capsule" EXACT [http://www.gudmap.org/About/Tutorial/DevMUS.html#DMK_Nephron] synonym: "Bowman's capsule" RELATED [TAO:0005254] synonym: "Bowmans capsule" EXACT [KUPO:0001001] -synonym: "capsula glomerularis" EXACT LATIN [] -synonym: "capsula glomeruli" RELATED LATIN [] +synonym: "capsula glomerularis" EXACT OMO:0003011 [] +synonym: "capsula glomeruli" RELATED OMO:0003011 [] synonym: "Malphigian capsule" RELATED MISSPELLING [BTO:0002297] synonym: "Malpighian capsule" RELATED [UBERON:cjm] synonym: "Mueller capsule" RELATED [BTO:0002297] @@ -10762,7 +10770,7 @@ synonym: "junctional tube" RELATED [Wikipedia:Connecting_tubule] synonym: "kidney collecting duct" EXACT [] synonym: "kidney collecting tubule" RELATED [] synonym: "renal collecting tubule" EXACT [FMA:15628] -synonym: "tubulus renalis arcuatus" EXACT LATIN [Wikipedia:Connecting_tubule] +synonym: "tubulus renalis arcuatus" EXACT OMO:0003011 [Wikipedia:Connecting_tubule] synonym: "tubulus renalis colligens" EXACT [] synonym: "ureteric tree" RELATED [EMAPA:28407] xref: BTO:0000761 @@ -10800,7 +10808,7 @@ synonym: "proctodeum" RELATED [] xref: BTO:0001680 xref: CALOHA:TS-2005 xref: EV:0100082 -xref: FBbt:00047153 +xref: FBbt:00047153 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:15711 xref: GAID:312 xref: galen:Anus @@ -10839,7 +10847,7 @@ subset: uberon_slim synonym: "bladder" BROAD [EHDAA2:0000174] synonym: "urocyst" RELATED [Wikipedia:Urinary_bladder] synonym: "vesica" RELATED [BTO:0001418] -synonym: "vesica urinaria" EXACT LATIN [Wikipedia:Urinary_bladder] +synonym: "vesica urinaria" EXACT OMO:0003011 [Wikipedia:Urinary_bladder] xref: AAO:0000623 xref: BTO:0001418 xref: CALOHA:TS-1090 @@ -10914,8 +10922,8 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "mature nephron" NARROW [EMAPA:28491] -synonym: "nephroneum" RELATED LATIN [Wikipedia:Nephron] -synonym: "tubulus renalis" RELATED LATIN [Wikipedia:Nephron] +synonym: "nephroneum" RELATED OMO:0003011 [Wikipedia:Nephron] +synonym: "tubulus renalis" RELATED OMO:0003011 [Wikipedia:Nephron] xref: BTO:0000924 xref: CALOHA:TS-1312 xref: EMAPA:28491 @@ -10957,8 +10965,8 @@ synonym: "PCT" RELATED [] synonym: "proximal convoluted renal tubule" EXACT [] synonym: "renal proximal convoluted tubule" RELATED [http://orcid.org/0000-0002-6601-2165] synonym: "tubulus contortus proximalis" EXACT [] -synonym: "tubulus contortus proximalis" RELATED LATIN [Wikipedia:Proximal_convoluted_tubule] -synonym: "tubulus convolutus proximalis" RELATED LATIN [] +synonym: "tubulus contortus proximalis" RELATED OMO:0003011 [Wikipedia:Proximal_convoluted_tubule] +synonym: "tubulus convolutus proximalis" RELATED OMO:0003011 [] xref: CALOHA:TS-2198 xref: EMAPA:28287 xref: EV:0100388 @@ -10988,7 +10996,7 @@ namespace: uberon def: "The section of the renal tubule in the kidney medulla with a hairpin bend; consists of a descending limb and an ascending limb, and is situated between the proximal convoluted tubule to the distal convoluted tubule; it functions to reabsorb water and ions from the urine." [MGI:csmith, MP:0004755] subset: pheno_slim subset: uberon_slim -synonym: "ansa nephroni" EXACT LATIN [Wikipedia:Loop_of_Henle] +synonym: "ansa nephroni" EXACT OMO:0003011 [Wikipedia:Loop_of_Henle] synonym: "Henle loop" EXACT [] synonym: "Henle's loop" EXACT [] xref: BTO:0004608 @@ -11088,8 +11096,8 @@ subset: uberon_slim synonym: "distal convoluted renal tubule" EXACT [] synonym: "second convoluted tubule" RELATED [] synonym: "tubulus contortus distalis" EXACT [] -synonym: "tubulus contortus distalis" RELATED LATIN [Wikipedia:Distal_convoluted_tubule] -synonym: "tubulus convolutus distalis" RELATED LATIN [] +synonym: "tubulus contortus distalis" RELATED OMO:0003011 [Wikipedia:Distal_convoluted_tubule] +synonym: "tubulus convolutus distalis" RELATED OMO:0003011 [] xref: EMAPA:28393 xref: EV:0100389 xref: FMA:17721 @@ -11121,8 +11129,8 @@ synonym: "outer zone of medulla of kidney" EXACT [] synonym: "outer zone of renal medulla" EXACT [] synonym: "renal outer medulla" EXACT [BTO:0001746] synonym: "set of outer region of renal pyramids" RELATED [FMA:17733] -synonym: "zona externa (medullaris renalis)" EXACT LATIN [FMA:17733, FMA:TA] -synonym: "zona externa medullae renalis" EXACT LATIN [FMA:17733, FMA:TA] +synonym: "zona externa (medullaris renalis)" EXACT OMO:0003011 [FMA:17733, FMA:TA] +synonym: "zona externa medullae renalis" EXACT OMO:0003011 [FMA:17733, FMA:TA] xref: BTO:0001746 xref: CALOHA:TS-0508 xref: EMAPA:28310 @@ -11251,10 +11259,11 @@ xref: BTO:0000545 xref: EHDAA2:0000726 xref: EHDAA:518 xref: EMAPA:16247 -xref: FBbt:00003125 +xref: FBbt:00003125 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:45615 xref: galen:AlimentaryTract xref: MA:0000917 +xref: MESH:D041981 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} xref: NCIT:C34082 xref: TAO:0000112 xref: TGMA:0001819 @@ -11281,6 +11290,7 @@ id: UBERON:0001556 name: lower urinary tract namespace: uberon def: "Subdivision of urinary system which consists of the urinary bladder and the urethra." [FMA:45659] +subset: human_reference_atlas subset: pheno_slim subset: uberon_slim xref: FMA:45659 @@ -11291,6 +11301,7 @@ is_a: UBERON:0011216 ! organ system subdivision relationship: has_part UBERON:0000057 ! urethra relationship: has_part UBERON:0001255 ! urinary bladder relationship: part_of UBERON:0001008 ! renal system +relationship: present_in_taxon NCBITaxon:9606 [Term] id: UBERON:0001630 @@ -11382,7 +11393,7 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "vascular element" RELATED [EMAPA:th] -synonym: "vena" RELATED LATIN [Wikipedia:Vein] +synonym: "vena" RELATED OMO:0003011 [Wikipedia:Vein] synonym: "venae" RELATED OMO:0003004 [VHOG:0001743] synonym: "venous subtree" BROAD [] synonym: "venous tree organ part" EXACT [] @@ -11487,7 +11498,7 @@ subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "venula" RELATED LATIN [Wikipedia:Venule] +synonym: "venula" RELATED OMO:0003011 [Wikipedia:Venule] xref: BTO:0002626 xref: EMAPA:35917 xref: FMA:63130 @@ -11516,7 +11527,7 @@ def: "The smallest division of the artery located between the muscular arteries subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "arteriola" RELATED LATIN [Wikipedia:Arteriole] +synonym: "arteriola" RELATED OMO:0003011 [Wikipedia:Arteriole] xref: AAO:0010253 xref: BTO:0001997 xref: EMAPA:35146 @@ -11553,7 +11564,7 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "region of vascular tree organ" EXACT [FMA:50722] -synonym: "vas sanguineum" RELATED LATIN [Wikipedia:Blood_vessel] +synonym: "vas sanguineum" RELATED OMO:0003011 [Wikipedia:Blood_vessel] synonym: "vascular element" BROAD [EMAPA:35993] synonym: "vascular tree organ region" EXACT [FMA:50722] xref: AAO:0011004 @@ -11711,7 +11722,7 @@ xref: BILA:0000034 xref: BTO:0000174 xref: CALOHA:TS-2110 xref: EFO:0000461 -xref: FBbt:00004208 +xref: FBbt:00004208 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:69067 xref: GAID:407 xref: MESH:D004628 @@ -11774,7 +11785,7 @@ def: "A cardiac atrium that is in the right side of the heart. It receives deoxy subset: human_reference_atlas subset: pheno_slim subset: uberon_slim -synonym: "atrium dextrum" RELATED LATIN [Wikipedia:Right_atrium] +synonym: "atrium dextrum" RELATED OMO:0003011 [Wikipedia:Right_atrium] synonym: "cardiac right atrium" EXACT [] synonym: "heart right atrium" EXACT [MA:0000075] synonym: "right atrium" EXACT [VHOG:0000328] @@ -11871,6 +11882,7 @@ xref: EMAPA:37721 {source="MA:th"} xref: FMA:71221 xref: MA:0002986 xref: MAT:0000148 +xref: MESH:D013131 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} xref: MIAA:0000148 xref: TAO:0000317 xref: VHOG:0000317 @@ -11900,7 +11912,7 @@ subset: vertebrate_core synonym: "appendicular skeleton" EXACT [] synonym: "entire appendicular skeleton" EXACT [https://github.com/obophenotype/uberon/issues/59] synonym: "paired fin skeleton" NARROW SENSU [] -synonym: "skeleton appendiculare" RELATED LATIN [Wikipedia:Appendicular_skeleton] +synonym: "skeleton appendiculare" RELATED OMO:0003011 [Wikipedia:Appendicular_skeleton] xref: AAO:0000747 xref: EFO:0000951 xref: EMAPA:32729 @@ -12035,7 +12047,7 @@ xref: EHDAA:1017 xref: EMAPA:16579 xref: FMA:72170 xref: MAT:0000117 -xref: MESH:D060910 +xref: MESH:D060910 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: MIAA:0000117 xref: NCIT:C34280 xref: SCTID:308804007 @@ -12135,7 +12147,7 @@ namespace: uberon def: "The part of the coelemic cavity lumen that is enclosed by the walls of the thorax." [UBERON:cjm, Wikipedia:Thoracic_cavity] subset: pheno_slim subset: uberon_slim -synonym: "cavitas thoracis" EXACT LATIN [Wikipedia:Thoracic_cavity] +synonym: "cavitas thoracis" EXACT OMO:0003011 [Wikipedia:Thoracic_cavity] synonym: "cavity of chest" EXACT [] synonym: "cavity of thorax" EXACT [] synonym: "chest cavity" EXACT [] @@ -12169,7 +12181,7 @@ def: "An anatomical structure which consists of juxtaglomerular cells, extraglom subset: human_reference_atlas subset: pheno_slim subset: uberon_slim -synonym: "complexus juxtaglomerularis" EXACT LATIN [] +synonym: "complexus juxtaglomerularis" EXACT OMO:0003011 [] synonym: "juxtaglomerular complex" EXACT [MP:0002829] xref: BTO:0005157 xref: EMAPA:30449 @@ -12256,7 +12268,7 @@ synonym: "ventral body cavity" NARROW [NCBITaxon:7742] xref: AEO:0000186 xref: BTO:0001707 xref: EHDAA2:0000267 -xref: FBbt:00005060 +xref: FBbt:00005060 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:85006 xref: galen:BodyCavity xref: NCIT:C25444 @@ -12282,7 +12294,7 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "embryonic notocord" EXACT [] -synonym: "notochorda" RELATED LATIN [Wikipedia:Notochord] +synonym: "notochorda" RELATED OMO:0003011 [Wikipedia:Notochord] synonym: "notocord" EXACT [ZFA:0000135] xref: AAO:0000327 xref: BTO:0001768 @@ -12341,7 +12353,7 @@ synonym: "epithelial somite" RELATED [https://github.com/obophenotype/uberon/wik synonym: "mesodermal cluster" BROAD [GO:0001756] synonym: "somites" RELATED OMO:0003004 [] synonym: "somitic mesoderm" RELATED [] -synonym: "somitus" RELATED LATIN [Wikipedia:Somite] +synonym: "somitus" RELATED OMO:0003011 [Wikipedia:Somite] xref: AAO:0010569 xref: AEO:0001015 xref: BTO:0001558 @@ -12407,7 +12419,7 @@ comment: Gene notes: Many factors and genes, such as Pax3 (Tremblay et al., 1995 subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "crista neuralis" RELATED LATIN [Wikipedia:Neural_crest] +synonym: "crista neuralis" RELATED OMO:0003011 [Wikipedia:Neural_crest] synonym: "NC" EXACT OMO:0003000 [XAO:0000048] synonym: "neural crest material" RELATED [VHOG:0000057] xref: AAO:0010578 @@ -12453,7 +12465,7 @@ namespace: uberon def: "Embryonic ectoderm that gives rise to nervous tissue." [Wikipedia:Neuroectoderm] subset: uberon_slim subset: vertebrate_core -synonym: "epithelium tubi neuralis; neuroectoderma" RELATED LATIN [Wikipedia:Neuroectoderm] +synonym: "epithelium tubi neuralis; neuroectoderma" RELATED OMO:0003011 [Wikipedia:Neuroectoderm] synonym: "neuaral ectoderm" RELATED [] synonym: "neural ectoderm" EXACT [] synonym: "neuroectoderm" EXACT [] @@ -12467,7 +12479,7 @@ xref: EHDAA:1498 xref: EHDAA:255 xref: EMAPA:16073 xref: EV:0100004 -xref: FBbt:00001057 +xref: FBbt:00001057 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:87657 xref: MAT:0000176 xref: MIAA:0000176 @@ -12670,7 +12682,7 @@ subset: vertebrate_core synonym: "blastocyst" RELATED [] synonym: "ectoblast" RELATED [MP:0003886] synonym: "epiblast" EXACT [VHOG:0000243] -synonym: "epiblastus" RELATED LATIN [Wikipedia:Epiblast] +synonym: "epiblastus" RELATED OMO:0003011 [Wikipedia:Epiblast] synonym: "primitive ectoderm" RELATED [VHOG:0000243] xref: BTO:0004593 xref: FMA:296704 @@ -12740,10 +12752,10 @@ def: "In mammals, the pronephric duct is the predecessor of the Wolffian duct[WP comment: The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the pronephric kidney[GOC:mtg_kidney_jan10, PMID:15647339, XAO:0000063, ZFA:0000150] subset: uberon_slim synonym: "archinephric duct" RELATED [VHOG:0000082] -synonym: "ductus pronephricus" RELATED LATIN [Wikipedia:Pronephric_duct] +synonym: "ductus pronephricus" RELATED OMO:0003011 [Wikipedia:Pronephric_duct] synonym: "pronephric ducts" RELATED OMO:0003004 [ZFA:0000150] xref: AAO:0011088 -xref: BTO:0005991 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: BTO:0005991 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: NCIT:C34279 xref: SCTID:361406002 xref: TAO:0000150 @@ -12809,7 +12821,7 @@ synonym: "IM" RELATED [] synonym: "intermediate mesenchyme" RELATED [https://github.com/obophenotype/uberon/wiki/The-neural-crest] synonym: "intermediate plate" RELATED [EMAPA:16178] synonym: "intermediate plate mesoderm" RELATED [https://orcid.org/0000-0002-6601-2165] -synonym: "mesenchyma intermedium" RELATED LATIN [Wikipedia:Intermediate_mesoderm] +synonym: "mesenchyma intermedium" RELATED OMO:0003011 [Wikipedia:Intermediate_mesoderm] xref: AAO:0010575 xref: EMAPA:16056 xref: EMAPA:16178 @@ -12864,12 +12876,12 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "archinephric duct" RELATED [VHOG:0000082, Wikipedia:Wolffian_duct] -synonym: "ductus mesonephricus; ductus Wolffi" RELATED LATIN [Wikipedia:Mesonephric_duct] +synonym: "ductus mesonephricus; ductus Wolffi" RELATED OMO:0003011 [Wikipedia:Mesonephric_duct] synonym: "Leydig's duct" RELATED [Wikipedia:Wolffian_duct] synonym: "renal duct" RELATED [] synonym: "Wolffian duct" EXACT [GOC:yaf, Wikipedia:Wolffian_duct, ZFA:0000546] xref: AAO:0000637 -xref: BTO:0005990 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: BTO:0005990 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: EHDAA2:0001243 xref: EHDAA:1590 xref: EMAPA:16577 @@ -12904,7 +12916,7 @@ def: "A region of embryonic ectodermal cells that lie directly above the notocho subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "lamina neuralis" RELATED LATIN [Wikipedia:Neural_plate] +synonym: "lamina neuralis" RELATED OMO:0003011 [Wikipedia:Neural_plate] synonym: "presumptive central nervous system" RELATED [] xref: AAO:0011072 xref: BTO:0001765 @@ -12914,7 +12926,7 @@ xref: EHDAA:346 xref: EHDAA:902 xref: EMAPA:35593 xref: FMA:293879 -xref: MESH:D054258 +xref: MESH:D054258 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: NCIT:C34225 xref: neuronames:1362 xref: RETIRED_EHDAA2:0001252 @@ -12942,7 +12954,7 @@ def: "The paraxial mesoderm is the mesoderm located bilaterally adjacent to the subset: efo_slim subset: uberon_slim subset: vertebrate_core -synonym: "mesoderma paraxiale" RELATED LATIN [Wikipedia:Paraxial_mesoderm] +synonym: "mesoderma paraxiale" RELATED OMO:0003011 [Wikipedia:Paraxial_mesoderm] synonym: "paraxial mesenchyme" EXACT [https://github.com/obophenotype/uberon/issues/30, https://github.com/obophenotype/uberon/wiki/The-neural-crest, ZFA:0000255] synonym: "somitic mesoderm" EXACT [ISBN:9780878932504] xref: AAO:0010568 @@ -12981,7 +12993,7 @@ synonym: "lateral mesoderm" EXACT [GO:0048368] synonym: "lateral plate" RELATED [] synonym: "lateral plate mesenchyme" RELATED [EHDAA2:0000919] synonym: "LPM" EXACT OMO:0003000 [ZFA:0000121] -synonym: "mesoderma laminae lateralis" RELATED LATIN [Wikipedia:Lateral_plate_mesoderm] +synonym: "mesoderma laminae lateralis" RELATED OMO:0003011 [Wikipedia:Lateral_plate_mesoderm] xref: AAO:0010574 xref: EHDAA2:0000919 xref: EHDAA:379 @@ -13042,10 +13054,10 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "sclerotomes" EXACT OMO:0003004 [TAO:0001080] -synonym: "sclerotomus" RELATED LATIN [Wikipedia:Sclerotome] +synonym: "sclerotomus" RELATED OMO:0003011 [Wikipedia:Sclerotome] xref: AAO:0010571 xref: AEO:0000212 -xref: BTO:0006255 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: BTO:0006255 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: EHDAA2:0003439 xref: EMAPA:31159 xref: FMA:295652 @@ -13096,7 +13108,7 @@ def: "Portion of tissue composed of mesenchymal cells (motile cells that develop subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "mesenchyma" RELATED LATIN [Wikipedia:Mesenchyme] +synonym: "mesenchyma" RELATED OMO:0003011 [Wikipedia:Mesenchyme] synonym: "mesenchymal tissue" EXACT [] synonym: "mesenchyme tissue" EXACT [] synonym: "portion of mesenchymal tissue" EXACT [] @@ -13398,7 +13410,7 @@ def: "Epithelial tubes transport gases, liquids and cells from one site to anoth synonym: "epithelial or endothelial tube" EXACT [] xref: AEO:0000114 xref: EHDAA2:0003114 -xref: FBbt:00007474 +xref: FBbt:00007474 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0000025 ! tube is_a: UBERON:0000483 ! epithelium intersection_of: UBERON:0000483 ! epithelium @@ -13471,7 +13483,7 @@ subset: human_reference_atlas subset: pheno_slim synonym: "collecting duct system" EXACT [Wikipedia:Collecting_duct_system] synonym: "kidney collecting duct system" EXACT [Wikipedia:Collecting_duct_system] -synonym: "tubulus renalis colligens" RELATED LATIN [Wikipedia:Collecting_duct_system] +synonym: "tubulus renalis colligens" RELATED OMO:0003011 [Wikipedia:Collecting_duct_system] xref: FMA:265239 xref: SCTID:279371005 xref: Wikipedia:Collecting_duct_system @@ -13772,6 +13784,7 @@ subset: pheno_slim synonym: "SSB" EXACT OMO:0003000 [] synonym: "stage II nephron" EXACT [http://www.gudmap.org/Organ_Summaries/Metanephros/Renal_vesicle.html] xref: EMAPA:27756 +xref: VO:0010896 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: ZFA:0005589 is_a: UBERON:0005423 ! developing anatomical structure relationship: develops_from UBERON:0004198 {source="GO"} ! comma-shaped body @@ -13794,7 +13807,7 @@ synonym: "medullary pyramid" RELATED [] synonym: "pyramid" BROAD [GO:0072056] synonym: "pyramid of Malphigi" RELATED MISSPELLING [ncithesaurus:Pyramid_of_Malpighi] synonym: "pyramid of Malpighi" RELATED [UBERON:cjm] -synonym: "pyramides renales" RELATED LATIN [Wikipedia:Renal_pyramids] +synonym: "pyramides renales" RELATED OMO:0003011 [Wikipedia:Renal_pyramids] synonym: "pyramis renalis" RELATED [BTO:0003926] synonym: "renal medullary region" RELATED [FMA:258870] synonym: "renal pyramid" EXACT [Wikipedia:Renal_pyramids] @@ -13831,7 +13844,7 @@ synonym: "outer stripe" EXACT [GO:0072058] synonym: "outer stripe of medulla of kidney" EXACT [FMA:76662] synonym: "outer stripe of outer medulla" EXACT [EMAPA:29663] synonym: "outer stripe of renal medulla" EXACT [FMA:76662] -synonym: "stria externa medullae renalis" EXACT LATIN [FMA:76662, FMA:TA] +synonym: "stria externa medullae renalis" EXACT OMO:0003011 [FMA:76662, FMA:TA] xref: EMAPA:29663 xref: FMA:76662 xref: MA:0002629 @@ -13973,7 +13986,7 @@ xref: EHDAA2:0001525 xref: EHDAA:185 xref: EMAPA:16072 xref: FMA:293110 -xref: MESH:D054240 +xref: MESH:D054240 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: NCIT:C28402 xref: SCTID:361438007 xref: UMLS:C0033153 {source="ncithesaurus:Primitive_Streak"} @@ -14108,6 +14121,7 @@ id: UBERON:0004638 name: blood vessel endothelium namespace: uberon def: "An endothelium that lines the blood vasculature. Other endothelia may line lymph vessels, the heart." [https://orcid.org/0000-0002-6601-2165] +subset: human_reference_atlas subset: pheno_slim subset: vertebrate_core xref: BTO:0000766 @@ -14122,6 +14136,7 @@ is_a: UBERON:0004852 ! cardiovascular system endothelium intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:0001981 ! blood vessel relationship: part_of UBERON:0001981 ! blood vessel +relationship: present_in_taxon NCBITaxon:9606 [Term] id: UBERON:0004639 @@ -14134,8 +14149,8 @@ subset: vertebrate_core synonym: "afferent arteriole" EXACT [MA:0002579] synonym: "afferent glomerular arteriole" EXACT [ZFA:0005307] synonym: "afferent glomerular arteriole of kidney" EXACT [FMA:77042] -synonym: "arteriola glomerularis afferens" RELATED LATIN [Wikipedia:Afferent_arterioles] -synonym: "arteriola glomerularis afferens renis" EXACT LATIN [FMA:77042, FMA:TA] +synonym: "arteriola glomerularis afferens" RELATED OMO:0003011 [Wikipedia:Afferent_arterioles] +synonym: "arteriola glomerularis afferens renis" EXACT OMO:0003011 [FMA:77042, FMA:TA] synonym: "kidney afferent arteriole" EXACT [MP:0011312] xref: EMAPA:28230 xref: EMAPA:28266 @@ -14185,8 +14200,8 @@ namespace: uberon def: "The branches of the arcuate arteries of the kidney that radiate outward throught the renal columns and supply the glomeruli[MP]. The first set of renal bloodvessels, the interlobular arteries (or cortical radiate arteries, or cortical radial arteries), are given off at right angles from the side of the arcuate arteries looking toward the cortical substance, and pass directly outward between the medullary rays to reach the fibrous tunic, where they end in the capillary network of this part. These vessels do not anastomose with each other, but form what are called end-arteries. In their outward course they give off lateral branches; these are the afferent vessels for the renal corpuscles; they enter the capsule, and end in the glomerulus. From each tuft the corresponding efferent vessel arises, and, having made its egress from the capsule near to the point where the afferent vessel enters, breaks up into a number of branches, which form a dense plexus within Bowman's capsule." [MP:0011316, Wikipedia:Interlobular_arteries] subset: human_reference_atlas subset: pheno_slim -synonym: "arteriae corticales radiatae" RELATED LATIN [Wikipedia:Interlobular_arteries] -synonym: "arteriae interlobulares renis" RELATED LATIN [Wikipedia:Interlobular_arteries] +synonym: "arteriae corticales radiatae" RELATED OMO:0003011 [Wikipedia:Interlobular_arteries] +synonym: "arteriae interlobulares renis" RELATED OMO:0003011 [Wikipedia:Interlobular_arteries] synonym: "cortical radial arteries" RELATED [Wikipedia:Interlobular_arteries] synonym: "interlobular" RELATED [Wikipedia:Interlobular_arteries] synonym: "interlobular renal artery" EXACT [FMA:70498] @@ -14223,7 +14238,7 @@ synonym: "trilaminar disk" RELATED [https://orcid.org/0000-0002-6601-2165] synonym: "trilaminar germ" RELATED [https://orcid.org/0000-0002-6601-2165] xref: BILA:0000060 xref: BTO:0001403 -xref: FBbt:00005317 +xref: FBbt:00005317 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:293108 xref: GAID:1302 xref: MESH:D005775 @@ -14393,7 +14408,7 @@ name: nephrogenic cord namespace: uberon def: "A portion of the urogenital ridge which is the source of much of the urinary system[WP]." [Wikipedia:Nephrogenic_cord] comment: part_of or develops_from urogenital ridge? -synonym: "chorda nephrogenica" RELATED LATIN [Wikipedia:Nephrogenic_cord] +synonym: "chorda nephrogenica" RELATED OMO:0003011 [Wikipedia:Nephrogenic_cord] xref: FMA:72168 xref: NCIT:C34219 xref: SCTID:361405003 @@ -14450,7 +14465,7 @@ namespace: uberon def: "Anatomical structure that connects two or more adjacent skeletal elements or hardened body parts." [http://orcid.org/0000-0002-6601-2165] subset: grouping_class synonym: "joint" NARROW [] -xref: FBbt:00005811 +xref: FBbt:00005811 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0034921 ! multi organ part structure relationship: part_of UBERON:0004770 ! articular system @@ -14466,7 +14481,7 @@ synonym: "gut section" RELATED [FBbt:00100315] synonym: "intestinal tract" RELATED [] synonym: "segment of intestinal tract" RELATED [] synonym: "subdivision of alimentary system" RELATED [FMA:71131] -xref: FBbt:00100315 +xref: FBbt:00100315 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:71131 is_a: UBERON:0013522 ! subdivision of tube intersection_of: UBERON:0013522 ! subdivision of tube @@ -14581,7 +14596,7 @@ property_value: IAO:0000232 "in some organisms such as drosophila, muscles can b id: UBERON:0005095 name: kidney rudiment namespace: uberon -def: "." [GO:0072003] +def: "Missing definition for term UBERON:0005095. Please replace it using linked reference." [GO:0072003] synonym: "kidney anlage" RELATED [GOC:mtg_kidney_jan10] is_a: UBERON:0002050 ! embryonic structure relationship: develops_from UBERON:0007687 {source="GO"} ! kidney field @@ -14624,7 +14639,7 @@ def: "The connecting tubule is a tubular segment of the nephron; it connects the subset: human_reference_atlas synonym: "connecting tubule" EXACT [MA:0002610] synonym: "kidney connecting tubule" EXACT [MA:0002610] -synonym: "tubulus renalis arcuatus" RELATED LATIN [Wikipedia:Connecting_tubule] +synonym: "tubulus renalis arcuatus" RELATED OMO:0003011 [Wikipedia:Connecting_tubule] xref: BTO:0004539 xref: EMAPA:27758 xref: EMAPA:27790 @@ -14910,7 +14925,7 @@ synonym: "developmental tissue" RELATED [MIAA:0000019] xref: AEO:0000125 xref: CALOHA:TS-2122 xref: EHDAA2:0003125 -xref: FBbt:00007006 +xref: FBbt:00007006 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:292313 xref: MIAA:0000019 is_a: UBERON:0000465 ! material anatomical entity @@ -14927,7 +14942,7 @@ def: "Multi-tissue structure that arises from the heart rudiment and will become subset: vertebrate_core synonym: "early primitive heart tube" NARROW [EMAPA:16208] synonym: "primitive heart tube" EXACT [EMAPA:16215] -xref: BTO:0006179 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: BTO:0006179 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: EHDAA2:0001512 xref: EHDAA:424 xref: EHDAA:436 @@ -15054,7 +15069,7 @@ namespace: uberon def: "An acellular membrane that is part of the epithelium, lies adjacent to the epithelial cells, and is the fusion of the the basal lamina and the reticular lamina." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Basement_membrane] synonym: "basement membrane" RELATED [FMA:63872] synonym: "basement membrane of connective tissue" EXACT [FMA:63872] -synonym: "membrana basalis" EXACT LATIN [Wikipedia:Basement_membrane] +synonym: "membrana basalis" EXACT OMO:0003011 [Wikipedia:Basement_membrane] xref: AAO:0010596 xref: FMA:63872 xref: GAID:915 @@ -15086,7 +15101,7 @@ xref: EMAPA:28251 xref: EMAPA:30965 xref: FMA:74274 xref: MA:0001659 -xref: MESH:D050533 +xref: MESH:D050533 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: NCIT:C32683 xref: SCTID:243897006 xref: TAO:0005285 @@ -15137,7 +15152,7 @@ def: "Subdivision of skeleton which consists of cranial skeleton, set of all ver subset: human_reference_atlas subset: pheno_slim subset: uberon_slim -synonym: "skeleton axiale" RELATED LATIN [Wikipedia:Axial_skeleton] +synonym: "skeleton axiale" RELATED OMO:0003011 [Wikipedia:Axial_skeleton] xref: AAO:0000963 xref: EMAPA:17214 xref: EMAPA:18043 @@ -15165,7 +15180,7 @@ def: "The membrane that covers the embryonic cloaca, formed by the union of proc subset: emapa_ehdaa2 subset: pheno_slim synonym: "embryonic cloacal membrane" EXACT [] -synonym: "membrana cloacalis" RELATED LATIN [Wikipedia:Cloacal_membrane] +synonym: "membrana cloacalis" RELATED OMO:0003011 [Wikipedia:Cloacal_membrane] xref: EHDAA2:0000257 xref: EHDAA:214 xref: EHDAA:2933 @@ -15424,7 +15439,7 @@ def: "The distalmost portion of the digestive tract, derived from the hindgut, a synonym: "rectal part of digestive tract" RELATED [] synonym: "rectum" NARROW [FBbt:00005756] synonym: "terminal section of digestive tract" RELATED [] -xref: FBbt:00005756 +xref: FBbt:00005756 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: WBbt:0005773 is_a: UBERON:0004921 ! subdivision of digestive tract relationship: continuous_with UBERON:0001245 ! anus @@ -15764,7 +15779,7 @@ synonym: "organ field" RELATED [] xref: AEO:0000170 xref: EFO:0001649 xref: EHDAA2:0003170 -xref: FBbt:00005426 +xref: FBbt:00005426 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: Wikipedia:Anlage_(biology) is_a: UBERON:0000479 {source="FBbt"} ! tissue is_a: UBERON:0005423 {source="AEO", source="FBbt"} ! developing anatomical structure @@ -15995,7 +16010,7 @@ def: "An artery that supplies a renal lobe." [http://orcid.org/0000-0002-6601-21 subset: human_reference_atlas subset: pheno_slim synonym: "arteriae interlobares renis" EXACT OMO:0003004 [FMA:TA] -synonym: "arteriae interlobares renis" RELATED LATIN [Wikipedia:Interlobar_arteries] +synonym: "arteriae interlobares renis" RELATED OMO:0003011 [Wikipedia:Interlobar_arteries] synonym: "interlobar arteries of kidney" RELATED [FMA:71637] synonym: "interlobar artery of kidney" EXACT [FMA:71637] synonym: "kidney interlobar artery" EXACT [] @@ -16019,7 +16034,7 @@ name: anatomical lobe namespace: uberon def: "A portion of an organ, such as the liver, lung, breast, or brain." [ncithesaurus:Lobe] subset: upper_level -synonym: "lobus" EXACT LATIN [FMA:45728, FMA:TA] +synonym: "lobus" EXACT OMO:0003011 [FMA:45728, FMA:TA] xref: FMA:45728 xref: NCIT:C13393 xref: UMLS:C0796494 @@ -16032,7 +16047,7 @@ namespace: uberon def: "The portion of a kidney consisting of a renal medullary pyramid and the renal cortex above it[MP]. It is composed of many renal lobules[WP]." [MP:0011381, Wikipedia:Renal_lobe] subset: pheno_slim synonym: "kidney lobe" EXACT [MP:0011381] -synonym: "lobi renales" RELATED LATIN [Wikipedia:Renal_lobe] +synonym: "lobi renales" RELATED OMO:0003011 [Wikipedia:Renal_lobe] synonym: "lobi renalis" EXACT OMO:0003004 [Wikipedia:Renal_lobe] synonym: "lobus renalis" EXACT [http://www.mondofacto.com/facts/dictionary?lobus+renalis] xref: FMA:17881 @@ -16057,7 +16072,7 @@ subset: common_anatomy subset: upper_level synonym: "multicellular structure" EXACT [FBbt:00100313] xref: CARO:0010000 -xref: FBbt:00100313 +xref: FBbt:00100313 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0000061 ! anatomical structure intersection_of: UBERON:0000061 ! anatomical structure intersection_of: has_quality PATO:0001993 ! multicellular @@ -16310,8 +16325,9 @@ name: organ system subdivision namespace: uberon def: "A subdivision of an anatomical system." [http://orcid.org/0000-0002-6601-2165] subset: common_anatomy +subset: human_reference_atlas subset: upper_level -xref: FBbt:00007330 +xref: FBbt:00007330 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:67509 xref: SCTID:91690000 is_a: UBERON:0010000 {source="FBbt"} ! multicellular anatomical structure @@ -16319,6 +16335,7 @@ relationship: part_of UBERON:0000467 ! anatomical system relationship: present_in_taxon NCBITaxon:33090 relationship: present_in_taxon NCBITaxon:33208 ! Metazoa relationship: present_in_taxon NCBITaxon:4751 +relationship: present_in_taxon NCBITaxon:9606 [Term] id: UBERON:0011249 @@ -16467,7 +16484,7 @@ id: UBERON:0013241 name: embryonic urethral groove namespace: uberon def: "The precursor of the urethra." [http://orcid.org/0000-0002-6601-2165] -synonym: "sulcus urethralis primarius" EXACT LATIN [Wikipedia:Urethral_groove] +synonym: "sulcus urethralis primarius" EXACT OMO:0003011 [Wikipedia:Urethral_groove] synonym: "urethral groove" EXACT [] synonym: "urethral sulcus" EXACT [] xref: SCTID:361531004 @@ -16515,7 +16532,6 @@ id: UBERON:0013702 name: body proper namespace: uberon def: "The region of the organism associated with the visceral organs." [AEO:0000103] -subset: human_reference_atlas subset: non_informative synonym: "body" RELATED [AEO:0000103] synonym: "whole body" RELATED [BTO:0001489] @@ -16525,7 +16541,6 @@ xref: EMAPA:36031 xref: FMA:231424 is_a: UBERON:0000475 {source="AEO"} ! organism subdivision relationship: part_of UBERON:0013701 ! main body axis -relationship: present_in_taxon NCBITaxon:9606 property_value: UBPROP:0000001 "Cardinal body part, which consists of a maximal set of diverse subclasses of organ and organ part spatially associated with the vertebral column and ribcage. Examples: There is only one body proper[FMA:231424]." xsd:string {source="FMA:231424"} [Term] @@ -16536,7 +16551,7 @@ def: "A blood that is part of a vein." [OBOL:automatic] synonym: "blood in vein" EXACT [FMA:83067] synonym: "portion of venous blood" EXACT [FMA:83067] synonym: "venous blood" EXACT [FMA:83067] -xref: BTO:0006187 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: BTO:0006187 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: FMA:83067 is_a: UBERON:0000178 ! blood intersection_of: UBERON:0000178 ! blood @@ -16717,7 +16732,7 @@ namespace: uberon def: "Material anatomical entity consisting of multiple anatomical structures that are not connected to each other." [CARO:0020000] subset: common_anatomy xref: CARO:0020000 -xref: FBbt:00007276 +xref: FBbt:00007276 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0000465 {source="CARO"} ! material anatomical entity relationship: composed_primarily_of UBERON:0000061 ! anatomical structure relationship: has_component UBERON:0000061 {minCardinality="2"} ! anatomical structure @@ -16829,11 +16844,13 @@ id: UBERON:0036295 name: renal pelvis/ureter namespace: uberon def: "The upper tract of the renal system. The renal pelvis is the large cavity in the middle of each kidney. Urine drains from each kidney through a long tube called the ureter, into the bladder, where it is stored until it is passed from the body through the urethra." [NCIT:C54419] +subset: human_reference_atlas synonym: "renal pelvis and ureter" EXACT [] synonym: "renal pelvis plus ureter" EXACT [] xref: NCIT:C54419 is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0011143 {source="NCIT"} ! upper urinary tract +relationship: present_in_taxon NCBITaxon:9606 [Term] id: UBERON:8410081 @@ -16854,7 +16871,7 @@ name: excretory system namespace: uberon def: "An anatomical system that eliminates waste products that arise as a result of metabolic activity." [GO:0007588] subset: human_reference_atlas -xref: BTO:0006338 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: BTO:0006338 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} is_a: UBERON:0000467 ! anatomical system intersection_of: UBERON:0000467 ! anatomical system intersection_of: capable_of GO:0046903 ! secretion @@ -17254,20 +17271,6 @@ property_value: seeAlso "https://github.com/obophenotype/uberon/wiki/Part-disjoi is_a: RO:0002323 ! mereotopologically related to expand_expression_to: "BFO_0000051 exactly 0 (BFO_0000050 some ?Y)" [] -[Typedef] -id: RO:0002203 -name: develops into -def: "inverse of develops from" [] -subset: RO:0002259 -property_value: IAO:0000114 IAO:0000125 -property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 -property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172 -property_value: IAO:0000117 https://orcid.org/0000-0003-1980-3228 -is_transitive: true -is_a: has_potential_to_develop_into ! has potential to develop into -is_a: RO:0002286 ! developmentally succeeded by -is_a: RO:0002388 ! has potential to directly develop into - [Typedef] id: RO:0002206 name: expressed in @@ -17288,7 +17291,7 @@ def: "inverse of directly develops from" [] subset: RO:0002259 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000118 "developmental precursor of" xsd:string -is_a: RO:0002203 ! develops into +is_a: develops_into ! develops into [Typedef] id: RO:0002222 @@ -17318,7 +17321,7 @@ def: "inverse of has developmental contribution from" [] subset: RO:0002259 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 -holds_over_chain: RO:0002203 part_of +holds_over_chain: develops_into part_of is_a: has_potential_to_developmentally_contribute_to ! has potential to developmentally contribute to is_a: RO:0002286 ! developmentally succeeded by @@ -18603,7 +18606,7 @@ range: BFO:0000004 ! independent continuant is_transitive: true is_a: has_developmental_contribution_from ! has developmental contribution from is_a: RO:0002258 ! developmentally preceded by -inverse_of: RO:0002203 ! develops into +inverse_of: develops_into ! develops into [Typedef] id: develops_from_part_of @@ -18630,6 +18633,22 @@ domain: UBERON:0001062 ! anatomical entity holds_over_chain: directly_develops_from located_in is_a: RO:0002258 ! developmentally preceded by +[Typedef] +id: develops_into +name: develops into +namespace: uberon +def: "inverse of develops from" [] +subset: RO:0002259 +xref: RO:0002203 +property_value: IAO:0000114 IAO:0000125 +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 +property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172 +property_value: IAO:0000117 https://orcid.org/0000-0003-1980-3228 +is_transitive: true +is_a: has_potential_to_develop_into ! has potential to develop into +is_a: RO:0002286 ! developmentally succeeded by +is_a: RO:0002388 ! has potential to directly develop into + [Typedef] id: directly_develops_from name: directly develops from @@ -18965,7 +18984,7 @@ is_a: RO:0002479 ! has part that occurs in id: has_high_plasma_membrane_amount name: obsolete has_high_plasma_membrane_amount def: "OBSOLETE A relation between a cell and molecule or complex such that every instance of the cell has a high number of instances of that molecule expressed on the cell surface. For the formal definition, see Masci et al (PMID:19243617)." [PMID:19243617] -comment: Replaced with RO:0015015, see https://github.com/obophenotype/cell-ontology/issues/1481 +property_value: term_tracker_item https://github.com/obophenotype/cell-ontology/issues/1481 is_obsolete: true replaced_by: RO:0015015 @@ -18992,7 +19011,7 @@ inverse_of: input_of ! input of id: has_low_plasma_membrane_amount name: obsolete has_low_plasma_membrane_amount def: "OBSOLETE A relation between a cell and molecule or complex such that every instance of the cell has a low number of instances of that molecule expressed on the cell surface. For the formal definition, see Masci et al (PMID:19243617)." [PMID:19243617] -comment: Replaced with RO:0015016, see https://github.com/obophenotype/cell-ontology/issues/1481 +property_value: term_tracker_item https://github.com/obophenotype/cell-ontology/issues/1481 is_obsolete: true replaced_by: RO:0015016 @@ -20380,21 +20399,21 @@ is_a: develops_from ! develops from id: transitively_anteriorly_connected_to name: transitively anteriorly connected to namespace: uberon -def: "." [http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern] +property_value: seeAlso "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" xsd:anyURI is_transitive: true [Typedef] id: transitively_distally_connected_to name: transitively distally connected to namespace: uberon -def: "." [http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern] +property_value: seeAlso "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" xsd:anyURI is_transitive: true [Typedef] id: transitively_proximally_connected_to name: transitively proximally connected to namespace: uberon -def: "." [http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern] +property_value: seeAlso "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" xsd:anyURI is_transitive: true [Typedef] diff --git a/src/ontology/subsets/kidney_upper_slim.owl b/src/ontology/subsets/kidney_upper_slim.owl index a5d1fc86e..a3abeb5aa 100644 --- a/src/ontology/subsets/kidney_upper_slim.owl +++ b/src/ontology/subsets/kidney_upper_slim.owl @@ -18,6 +18,7 @@ xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#" xmlns:skos="http://www.w3.org/2004/02/skos/core#" xmlns:swrl="http://www.w3.org/2003/11/swrl#" + xmlns:sssom="https://w3id.org/sssom/" xmlns:swrla="http://swrl.stanford.edu/ontologies/3.3/swrla.owl#" xmlns:swrlb="http://www.w3.org/2003/11/swrlb#" xmlns:terms="http://purl.org/dc/terms/" @@ -29,8 +30,8 @@ xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#" xmlns:ncbitaxon="http://purl.obolibrary.org/obo/ncbitaxon#"> - - 2024-01-04 + + 2024-02-13 @@ -315,6 +316,14 @@ Annotations: IAO_0000424 "http://purl.obolibrary.org/obo/BFO_0000051 some ( + + + + + + + + @@ -337,6 +346,14 @@ Annotations: IAO_0000424 "http://purl.obolibrary.org/obo/BFO_0000051 some ( + + + + + + + + @@ -846,25 +863,25 @@ WHERE { - + - + - + - + - + - + @@ -1071,14 +1088,6 @@ WHERE { - - - - - - - - @@ -1103,14 +1112,6 @@ WHERE { - - - - - - - - @@ -1942,6 +1943,24 @@ WHERE { + + + + + + + + + + + + + + + + + + - - - - - - - - - - - - - - - - - - - - - A nucleus size quality which is relatively high compared to the amount of cytoplasm present in the same cell. - - 2009-12-23T10:53:24Z - increased nucleus size - - - - - A nucleus size quality which is relatively high compared to the amount of cytoplasm present in the same cell. - GOC:tfm - - - - @@ -12544,6 +12571,7 @@ For example, A and B may be gene products and binding of B by A positively regul An epithelial cell that is part of the nephron. FMA:70965 + epithelial cell of nephron @@ -12581,6 +12609,7 @@ For example, A and B may be gene products and binding of B by A positively regul KUPO:0001034 Bowmans capsule epithelial cell epithelial cell of Bowman's capsule + epithelial cell of glomerular capsule @@ -12621,6 +12650,7 @@ For example, A and B may be gene products and binding of B by A positively regul FMA:70982 KUPO:0001059 epithelial cell of renal collecting tubule + kidney collecting duct epithelial cell @@ -12678,6 +12708,7 @@ For example, A and B may be gene products and binding of B by A positively regul FMA:86785 KUPO:0001022 kidney tubule epithelial cell + This needs to be further defined as a juxtamedullary nephron. Will request the juxtamedullary nephron tubule class from UBERON. nephron tubule epithelial cell @@ -12713,6 +12744,7 @@ For example, A and B may be gene products and binding of B by A positively regul A cell that is part of a kidney. KUPO:0001010 + kidney cell @@ -12742,6 +12774,7 @@ For example, A and B may be gene products and binding of B by A positively regul A cell that is part of kidney interstitium. KUPO:0001013 + kidney interstitial cell @@ -12856,6 +12889,7 @@ For example, A and B may be gene products and binding of B by A positively regul KUPO:0001023 + kidney glomerular epithelial cell @@ -12978,6 +13012,7 @@ For example, A and B may be gene products and binding of B by A positively regul KUPO:0001024 + kidney cortex tubule cell @@ -13048,6 +13083,7 @@ For example, A and B may be gene products and binding of B by A positively regul KUPO:0001102 + kidney interstitial fibroblast @@ -13111,6 +13147,7 @@ For example, A and B may be gene products and binding of B by A positively regul KUPO:0001058 + kidney connecting tubule epithelial cell @@ -13147,6 +13184,7 @@ For example, A and B may be gene products and binding of B by A positively regul KUPO:0001056 + kidney distal convoluted tubule epithelial cell @@ -13257,6 +13295,7 @@ For example, A and B may be gene products and binding of B by A positively regul KUPO:0001030 + kidney capillary endothelial cell @@ -13319,6 +13358,7 @@ For example, A and B may be gene products and binding of B by A positively regul KUPO:0001047 + kidney loop of Henle epithelial cell @@ -13353,6 +13393,7 @@ For example, A and B may be gene products and binding of B by A positively regul KUPO:0001048 + kidney loop of Henle ascending limb epithelial cell @@ -13423,6 +13464,7 @@ For example, A and B may be gene products and binding of B by A positively regul A cell that is part of a collecting duct of renal tubule. KUPO:0001012 Wikipedia:Kidney_collecting_duct_cell + kidney collecting duct cell @@ -13447,6 +13489,7 @@ For example, A and B may be gene products and binding of B by A positively regul A pericyte cell located in the kidney interstitium. KUPO:0001104 + renal interstitial pericyte @@ -14770,7 +14813,7 @@ For example, A and B may be gene products and binding of B by A positively regul - A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex). + A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex). https://github.com/geneontology/go-ontology/issues/17729 GO:0008372 NIF_Subcellular:sao1337158144 @@ -14791,7 +14834,7 @@ For example, A and B may be gene products and binding of B by A positively regul - A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex). + A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex). GOC:pdt @@ -14821,8 +14864,8 @@ For example, A and B may be gene products and binding of B by A positively regul + - Note that this term is intended to annotate gene products that are not attached to the cell surface. For gene products from multicellular organisms which are secreted from a cell but retained within the organism (i.e. released into the interstitial fluid or blood), consider the cellular component term 'extracellular space ; GO:0005615'. extracellular region @@ -14867,32 +14910,32 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + A protein complex consisting of three collagen chains assembled into a left-handed triple helix. These trimers typically assemble into higher order structures. Wikipedia:Collagen cellular_component GO:0005581 collagen trimer - + - + - + PMID:12382326 - + PMID:12382326 @@ -14974,7 +15017,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Note that for multicellular organisms, the extracellular space refers to everything outside a cell, but still within the organism (excluding the extracellular matrix). Gene products from a multi-cellular organism that are secreted from a cell into the interstitial fluid or blood can therefore be annotated to this term. extracellular space @@ -15114,8 +15157,8 @@ For example, A and B may be gene products and binding of B by A positively regul + - Chromosomes include parts that are not part of the chromatin. Examples include the kinetochore. chromosome @@ -15181,8 +15224,8 @@ For example, A and B may be gene products and binding of B by A positively regul + - cytoplasm @@ -15342,8 +15385,8 @@ For example, A and B may be gene products and binding of B by A positively regul + - ribosome @@ -15384,8 +15427,8 @@ For example, A and B may be gene products and binding of B by A positively regul + - cytoskeleton @@ -15470,8 +15513,8 @@ For example, A and B may be gene products and binding of B by A positively regul + - plasma membrane @@ -15689,7 +15732,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + translation @@ -15817,7 +15860,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Note that this term should not be used for direct annotation. It should be possible to make a more specific annotation to one of the children of this term, for e.g. to transmembrane transport, to microtubule-based transport or to vesicle-mediated transport. transport @@ -16146,8 +16189,8 @@ For example, A and B may be gene products and binding of B by A positively regul + - cytoskeleton organization @@ -16933,7 +16976,7 @@ For example, A and B may be gene products and binding of B by A positively regul necrosis GO:0008219 - This term should not be used for direct annotation, it is currently kept in GO as a placeholder for describing cell death phenotypes in uPHENO. When information is provided on a programmed cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'). Unintentional cell death, i.e. cell death caused by injury, ageing, or cell phenotypes observed as a result of a pathological mutation in an essential gene should NOT be annotated using GO terms. + This term should not be used for direct annotation, it is currently kept in GO as a placeholder for describing cell death phenotypes in uPHENO. When information is provided on a programmed cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'). Unintentional cell death, i.e. cell death caused by injury, ageing, or cell phenotypes observed as a result of a pathological mutation in an essential gene should NOT be annotated using GO terms. cell death @@ -17439,7 +17482,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Note that this term should be used to annotate gene products in the organism undergoing the programmed cell death. To annotate genes in another organism whose products modulate programmed cell death in a host organism, consider the term 'modulation by symbiont of host programmed cell death ; GO:0052040'. Also, note that 'programmed cell death ; GO:0012501' should be used to refer to instances of caspase-independent cell death mechanisms, in the absence of further indications on the process taking place. At present, caspase-independent cell death is not yet represented in GO due to the lack of consensus and in-depth research on the topic. 'programmed cell death ; GO:0012501' may also be used to annotate gene products in taxa where apoptosis as defined in GO:0006915 does not occur, such as plants. You may also consider these specific children: GO:0097468 'programmed cell death in response to reactive oxygen species' (with descendants GO:0010421 'hydrogen peroxide-mediated programmed cell death' and GO:0010343 'singlet oxygen-mediated programmed cell death'), and GO:0009626 'plant-type hypersensitive response' and its children. programmed cell death @@ -18371,8 +18414,8 @@ For example, A and B may be gene products and binding of B by A positively regul + - Note that a signal is any variable property or parameter that serves to convey information, and may be a physical entity such as a gene product or small molecule, a photon, or a change in state such as movement or voltage change. signaling @@ -18464,7 +18507,7 @@ For example, A and B may be gene products and binding of B by A positively regul cell projection organization and biogenesis cell surface structure organization and biogenesis GO:0030030 - + cell projection organization @@ -19004,7 +19047,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + extracellular matrix @@ -20238,7 +20281,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + cell projection @@ -20323,6 +20366,7 @@ For example, A and B may be gene products and binding of B by A positively regul The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. + https://github.com/geneontology/go-ontology/issues/26424 GO:0034960 GO:0043283 GO:0044259 @@ -20332,6 +20376,7 @@ For example, A and B may be gene products and binding of B by A positively regul multicellular organismal macromolecule metabolic process biological_process GO:0043170 + macromolecule metabolic process @@ -20362,7 +20407,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + organelle @@ -20785,9 +20830,11 @@ For example, A and B may be gene products and binding of B by A positively regul The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism. + https://github.com/geneontology/go-ontology/issues/26424 primary metabolism biological_process GO:0044238 + primary metabolic process @@ -21568,9 +21615,11 @@ For example, A and B may be gene products and binding of B by A positively regul The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. + https://github.com/geneontology/go-ontology/issues/26424 development of an anatomical structure biological_process GO:0048856 + @@ -21618,7 +21667,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + cell motility @@ -21901,7 +21950,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. response to stimulus @@ -22838,7 +22887,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + protein-containing complex assembly @@ -23242,6 +23291,7 @@ For example, A and B may be gene products and binding of B by A positively regul The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon. + https://github.com/geneontology/go-ontology/issues/26424 mah 2010-03-08T03:32:18Z organic molecular entity metabolic process @@ -23249,6 +23299,7 @@ For example, A and B may be gene products and binding of B by A positively regul organic substance metabolism biological_process GO:0071704 + organic substance metabolic process @@ -23362,7 +23413,7 @@ For example, A and B may be gene products and binding of B by A positively regul - The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures. + The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures. mah 2010-10-04T01:51:47Z cellular_component @@ -23373,7 +23424,7 @@ For example, A and B may be gene products and binding of B by A positively regul - The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures. + The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures. GOC:pdt @@ -24402,6 +24453,7 @@ For example, A and B may be gene products and binding of B by A positively regul A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex but below that of an anatomical system. Or, a substance produced by a cellular organism with granularity above the level of a protein complex. https://github.com/geneontology/go-ontology/issues/24200 + https://github.com/geneontology/go-ontology/issues/26424 kmv 2019-08-12T18:01:37Z cellular_component @@ -25746,57 +25798,6 @@ For example, A and B may be gene products and binding of B by A positively regul - - - - - quality - PATO:0000068 - TODO: define this or obsolete it and move children somewhere else. - qualitative - - - - - - - - - A quality inhering in a bearer by virtue of the whether the bearer differs from normal or average. - quality - PATO:0000069 - - deviation (from_normal) - - - - - A quality inhering in a bearer by virtue of the whether the bearer differs from normal or average. - PATOC:GVG - - - - - - - - - A morphology quality inhering in a bearer by virtue of the bearer's physical magnitude. - quality - PATO:0000117 - - - size - - - - - A morphology quality inhering in a bearer by virtue of the bearer's physical magnitude. - WordNet:WordNet - - - - @@ -25872,67 +25873,6 @@ For example, A and B may be gene products and binding of B by A positively regul - - - - - A quality inhering in a bearer by virtue of the bearer's exhibiting no deviation from normal or average. - - quality - average - PATO:0000461 - - - - normal - - - - - A quality inhering in a bearer by virtue of the bearer's exhibiting no deviation from normal or average. - PATOC:GVG - - - - - - - - - - - - - - - - - - - - - A size quality which is relatively high. - - PATO:0001202 - quality - big - enlarged - expanded - great - large - PATO:0000586 - - increased size - - - - - A size quality which is relatively high. - PATOC:GVG - - - - @@ -26666,77 +26606,6 @@ For example, A and B may be gene products and binding of B by A positively regul - - - - - - - - - - - - - - - - - - - - - - A quality that has a value that is increased compared to normal or average. - - - 2011-06-16T06:39:43Z - quality - PATO:0002300 - increased quality - - - - - A quality that has a value that is increased compared to normal or average. - PATOC:GVG - - - - - - - - - - - - - - - - - - - - - A quality of an object that has a value that is increased compared to normal or average. - - - 2011-06-16T06:54:01Z - quality - PATO:0002305 - increased object quality - - - - - A quality of an object that has a value that is increased compared to normal or average. - PATOC:GVG - - - - @@ -26907,6 +26776,28 @@ For example, A and B may be gene products and binding of B by A positively regul + + + + + A quality inhering in a cell by virtue of the cell having a high nuclear/cytoplasmic ratio. + http://orcid.org/0000-0001-5208-3432 + high N:C ratio + quality + PATO:0040072 + A high nuclear/cytolasmic ratio is 70% or higher. + high nuclear/cytoplasmic ratio + + + + + A quality inhering in a cell by virtue of the cell having a high nuclear/cytoplasmic ratio. + Wikipedia:NC_ratio&oldid=931936284 + http://lymerick.net/blood-cells.pdf + + + + @@ -28250,6 +28141,12 @@ For example, A and B may be gene products and binding of B by A positively regul EMAPA:37283 MA:th + + + + FBbt:00007000 + + @@ -28325,7 +28222,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -28385,14 +28282,14 @@ For example, A and B may be gene products and binding of B by A positively regul ureter https://upload.wikimedia.org/wikipedia/commons/3/30/Urinary_system.svg - + - + GO @@ -28464,8 +28361,8 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + @@ -28515,25 +28412,25 @@ For example, A and B may be gene products and binding of B by A positively regul urethra https://upload.wikimedia.org/wikipedia/commons/c/cb/Female_anatomy.png - + - + - + pelvic part of UG sinus gives rise to prostatic and membranous parts of urethra Wikipedia - + Wikipedia @@ -28611,6 +28508,12 @@ For example, A and B may be gene products and binding of B by A positively regul A tube shaped portion of tissue lined with epithelial cells that collects secretions and routes them to their destination[ZFA:0005171]. ZFA:0005171 + + + + FBbt:00100314 + + @@ -28732,6 +28635,12 @@ For example, A and B may be gene products and binding of B by A positively regul Material anatomical entity that is a single connected structure with inherent 3D shape generated by coordinated expression of the organism's own genome. CARO:0000003 + + + + FBbt:00007001 + + @@ -29080,7 +28989,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -29131,14 +29040,14 @@ For example, A and B may be gene products and binding of B by A positively regul http://upload.wikimedia.org/wikipedia/commons/3/30/Gray1130.svg https://upload.wikimedia.org/wikipedia/commons/2/22/Renal_corpuscle.svg - + - + FMA MA @@ -29203,7 +29112,7 @@ For example, A and B may be gene products and binding of B by A positively regul glomerulus renis Wikipedia:Glomerulus - + @@ -29435,15 +29344,15 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + - + @@ -29479,34 +29388,34 @@ For example, A and B may be gene products and binding of B by A positively regul metanephros - + - + - + - + definitional - + GO - + ISBN:9780878932504 @@ -29645,7 +29554,7 @@ For example, A and B may be gene products and binding of B by A positively regul tubuli mesonephrici Wikipedia:Mesonephric_tubules - + @@ -29663,8 +29572,8 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + An epithelial swelling on the Wolffian duct that elongates to invade the adjacent metanephric mesenchyme[MP]. Outgrowth of the mesonephric duct that penetrates the metanephric mesoderm and forms the ureter, renal pelvis, major and minor calyces and collecting ducts. [Embryology, See_Dudek_RW_and_Fix_JD, Third_Edition_(2004)_Philadelphia:_Lippincott_William_and_Wilkins, p.137][VHOG] Outgrowth of the mesonephric duct that penetrates the metanephric mesoderm and forms the ureter, renal pelvis, major and minor calyces and collecting ducts[VHOG:0000541]. @@ -29691,11 +29600,11 @@ For example, A and B may be gene products and binding of B by A positively regul ureteric bud - + - + @@ -29708,13 +29617,13 @@ For example, A and B may be gene products and binding of B by A positively regul - + EHDAA2 - + ISBN:9780878932504 @@ -29766,14 +29675,14 @@ For example, A and B may be gene products and binding of B by A positively regul diverticulum metanephricum Wikipedia:Ureteric_bud - + gemma ureterica Wikipedia:Ureteric_bud - + @@ -29998,7 +29907,9 @@ For example, A and B may be gene products and binding of B by A positively regul IDOMAL:0000302 - https://orcid.org/0000-0003-4423-4370 + + + https://github.com/biopragmatics/biomappings @@ -30023,7 +29934,7 @@ For example, A and B may be gene products and binding of B by A positively regul zygotum Wikipedia:Zygote - + @@ -30147,7 +30058,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -30183,14 +30094,14 @@ For example, A and B may be gene products and binding of B by A positively regul gastrula stage - + - + BILS @@ -30468,8 +30379,8 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + @@ -30502,24 +30413,24 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0000162 cloaca - + - + - + ZFA - + AAO @@ -30601,8 +30512,8 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + @@ -30621,24 +30532,24 @@ For example, A and B may be gene products and binding of B by A positively regul embryonic cloaca - + - + - + EHDAA2 - + EHDAA2 @@ -30661,7 +30572,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -30703,14 +30614,14 @@ For example, A and B may be gene products and binding of B by A positively regul primitive urogenital sinus http://upload.wikimedia.org/wikipedia/commons/6/6d/Gray1109.png - + - + MP-def @@ -30774,7 +30685,7 @@ For example, A and B may be gene products and binding of B by A positively regul sinus urogenitalis - + @@ -30910,6 +30821,12 @@ For example, A and B may be gene products and binding of B by A positively regul in FMA, the tongue, palate etc are part of the mouth which is itself a subdivision of the face. ZFA includes a separate class 'oral region' which is part of the mouth, but excludes tongue and lips FMA + + + + FBbt:00003126 + + @@ -30917,14 +30834,14 @@ For example, A and B may be gene products and binding of B by A positively regul BTO:0004698 FMA:49184 FMA:TA - + cavital oralis Wikipedia:Mouth - + @@ -31066,15 +30983,15 @@ For example, A and B may be gene products and binding of B by A positively regul - + - - + + A fluid that is composed of blood plasma and erythrocytes. This class excludes blood analogues, such as the insect analog of blood. See UBERON:0000179 haemolymphatic fluid. @@ -31116,34 +31033,34 @@ For example, A and B may be gene products and binding of B by A positively regul blood - + - + - + - + CL:tm - + https://github.com/obophenotype/uberon/issues/1330 - + Bgee:AN @@ -31338,6 +31255,7 @@ For example, A and B may be gene products and binding of B by A positively regul parenchymal Early in development the mammalian embryo has three distinct layers: ectoderm (external layer), endoderm (internal layer) and in between those two layers the middle layer or mesoderm. The parenchyma of most organs is of ectodermal (brain, skin) or endodermal origin (lungs, gastrointestinal tract, liver, pancreas). The parenchyma of a few organs (spleen, kidneys, heart) is of mesodermal origin. The stroma of all organs is of mesodermal origin the FMA definition is more restrictive, and limits this to solid organs. This would seem to cause problems for the lung parenchyma, except FMA classifies Lung as solid rather than cavitated + BTO:0000999 BTO:0001539 EHDAA:3015 EHDAA:3905 @@ -31377,11 +31295,21 @@ For example, A and B may be gene products and binding of B by A positively regul the FMA definition is more restrictive, and limits this to solid organs. This would seem to cause problems for the lung parenchyma, except FMA classifies Lung as solid rather than cavitated FMA + + + + BTO:0000999 + + + https://github.com/biopragmatics/biomappings + BTO:0001539 - https://orcid.org/0000-0003-4423-4370 + + + https://github.com/biopragmatics/biomappings @@ -31499,7 +31427,7 @@ For example, A and B may be gene products and binding of B by A positively regul medulla renalis FMA:74268 FMA:TA - + @@ -31507,7 +31435,7 @@ For example, A and B may be gene products and binding of B by A positively regul pyramides renales FMA:74268 FMA:TA - + @@ -31683,7 +31611,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -31725,14 +31653,14 @@ For example, A and B may be gene products and binding of B by A positively regul organism substance - + - + this relationship may be too strong and may be weakened in future @@ -31741,6 +31669,12 @@ For example, A and B may be gene products and binding of B by A positively regul Material anatomical entity in a gaseous, liquid, semisolid or solid state; produced by anatomical structures or derived from inhaled and ingested substances that have been modified by anatomical structures as they pass through the body. http://orcid.org/0000-0001-9114-8737 + + + + FBbt:00007019 + + @@ -31819,6 +31753,12 @@ For example, A and B may be gene products and binding of B by A positively regul Non-material anatomical entity of three dimensions, that is generated by morphogenetic or other physiologic processes; is surrounded by one or more anatomical structures; contains one or more organism substances or anatomical structures. http://orcid.org/0000-0001-9114-8737 + + + + FBbt:00007017 + + @@ -31868,6 +31808,12 @@ For example, A and B may be gene products and binding of B by A positively regul Anatomical entity that has mass. http://orcid.org/0000-0001-9114-8737 + + + + FBbt:00007016 + + @@ -31904,6 +31850,12 @@ For example, A and B may be gene products and binding of B by A positively regul Anatomical entity that has no mass. http://orcid.org/0000-0001-9114-8737 + + + + FBbt:00007015 + + @@ -31989,11 +31941,19 @@ For example, A and B may be gene products and binding of B by A positively regul system GO:0048731 + + + + FBbt:00004856 + + IDOMAL:0002460 - https://orcid.org/0000-0003-4423-4370 + + + https://github.com/biopragmatics/biomappings @@ -32092,6 +32052,12 @@ For example, A and B may be gene products and binding of B by A positively regul VHOG:0000671 WBbt:0007833 + + + + FBbt:00000001 + + @@ -32240,6 +32206,12 @@ For example, A and B may be gene products and binding of B by A positively regul CARO:DOS http://orcid.org/0000-0001-9114-8737 + + + + FBbt:00007009 + + @@ -32307,6 +32279,12 @@ For example, A and B may be gene products and binding of B by A positively regul Anatomical structure that consists of cell parts and cell substances and together does not constitute a cell or a tissue. http://orcid.org/0000-0001-9114-8737 + + + + FBbt:00007013 + + @@ -32326,7 +32304,6 @@ For example, A and B may be gene products and binding of B by A positively regul FBbt:00007277 - IDOMAL:0002461 VHOG:0001737 uberon UBERON:0000477 @@ -32343,8 +32320,8 @@ For example, A and B may be gene products and binding of B by A positively regul - IDOMAL:0002461 - https://orcid.org/0000-0003-4423-4370 + FBbt:00007277 + @@ -32415,6 +32392,12 @@ For example, A and B may be gene products and binding of B by A positively regul Multicellular anatomical structure that consists of many cells of one or a few types, arranged in an extracellular matrix such that their long-range organisation is at least partly a repetition of their short-range organisation. CARO:0000043 + + + + FBbt:00007003 + + @@ -32482,6 +32465,12 @@ For example, A and B may be gene products and binding of B by A positively regul CARO:0000055 http://orcid.org/0000-0001-9114-8737 + + + + FBbt:00007010 + + @@ -32520,7 +32509,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -32564,14 +32553,14 @@ For example, A and B may be gene products and binding of B by A positively regul epithelium https://upload.wikimedia.org/wikipedia/commons/8/8f/Illu_epithelium.jpg - + - + http://palaeos.com/metazoa/porifera/homoscleromorpha.html @@ -32591,6 +32580,12 @@ For example, A and B may be gene products and binding of B by A positively regul ISBN:978-0030259821 Ruppert EE, Fox RS, Barnes RD, Invertebrate zoology: a functional evolutionary approach (2003) p.59 http://bgee.unil.ch/ + + + + FBbt:00007005 + + @@ -32659,6 +32654,12 @@ For example, A and B may be gene products and binding of B by A positively regul columnar epithlium AEO:0000068 + + + + FBbt:00007027 + + @@ -32954,7 +32955,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -32991,14 +32992,14 @@ For example, A and B may be gene products and binding of B by A positively regul abdomen - + - + MA @@ -33112,11 +33113,19 @@ For example, A and B may be gene products and binding of B by A positively regul Obsoleted in ZFA. Note that embryo is not classified as an embryonic structure - an embryonic structure is only the parts of an embryo ZFA + + + + FBbt:00000052 + + IDOMAL:0000646 - https://orcid.org/0000-0003-4423-4370 + + + https://github.com/biopragmatics/biomappings @@ -33203,6 +33212,12 @@ For example, A and B may be gene products and binding of B by A positively regul embryonic tissue FMA:69069 + + + + FBbt:00000110 + + @@ -33241,7 +33256,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Primary germ layer that is the outer of the embryo's three germ layers and gives rise to epidermis and neural tissue. Primary germ layer that is the outer of the embryonic germ layers and gives rise to epidermis and neural tissue.[AAO] The Bilateria are triploblastic (with true endoderm, mesoderm, and ectoderm) (...).[well established][VHOG] @@ -33279,14 +33294,14 @@ For example, A and B may be gene products and binding of B by A positively regul ectoderm http://upload.wikimedia.org/wikipedia/commons/1/19/Gray32.png - + - + Bgee:AN @@ -33314,6 +33329,12 @@ For example, A and B may be gene products and binding of B by A positively regul ISBN:978-0878932504 Gilbert SF, Developmental Biology (2006) Limb development and evolution, p.722 http://bgee.unil.ch/ + + + + FBbt:00000111 + + @@ -33339,7 +33360,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Primary germ layer that lies remote from the surface of the embryo and gives rise to internal tissues such as gut. The Bilateria are triploblastic (with true endoderm, mesoderm, and ectoderm) (...).[well established][VHOG] endodermal @@ -33376,14 +33397,14 @@ For example, A and B may be gene products and binding of B by A positively regul http://upload.wikimedia.org/wikipedia/commons/c/c0/Endoderm2.png http://upload.wikimedia.org/wikipedia/commons/d/df/Gray10.png - + - + Bgee:AN @@ -33402,6 +33423,12 @@ For example, A and B may be gene products and binding of B by A positively regul ISBN:978-0878932504 Gilbert SF, Developmental Biology (2006) Limb development and evolution, p.722 http://bgee.unil.ch/ + + + + FBbt:00000125 + + @@ -33428,7 +33455,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + The middle germ layer of the embryo, between the endoderm and ectoderm. Primary germ layer that is the middle of the embryonic germ layers.[AAO] @@ -33473,7 +33500,7 @@ For example, A and B may be gene products and binding of B by A positively regul mesoderm http://upload.wikimedia.org/wikipedia/commons/e/e8/Mesoderm.png - + @@ -33486,7 +33513,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Bgee:AN @@ -33520,6 +33547,12 @@ For example, A and B may be gene products and binding of B by A positively regul sponges do not seem to have a mesoderm and accordingly Amphimedon lacks transcription factors involved in mesoderm development (Fkh, Gsc, Twist, Snail)[http://www.nature.com/nature/journal/v466/n7307/full/nature09201.html]. Mesoderm may not be homologous across verteberates https://github.com/obophenotype/uberon/wiki/The-neural-crest + + + + FBbt:00000126 + + @@ -33629,6 +33662,12 @@ For example, A and B may be gene products and binding of B by A positively regul stomodeal-hypophyseal primordium XAO:0000269 + + + + FBbt:00000439 + + @@ -33685,7 +33724,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -33731,7 +33770,7 @@ For example, A and B may be gene products and binding of B by A positively regul proctodeum https://github.com/obophenotype/uberon/issues/685 - + @@ -33744,7 +33783,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + EHDAA2 @@ -33773,6 +33812,12 @@ For example, A and B may be gene products and binding of B by A positively regul AAO ZFA:0000066 + + + + FBbt:00000123 + + @@ -33818,7 +33863,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -33895,14 +33940,14 @@ For example, A and B may be gene products and binding of B by A positively regul https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Heart.glb https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Heart.glb - + - + MA @@ -34218,6 +34263,7 @@ For example, A and B may be gene products and binding of B by A positively regul Anatomical system that has as its parts the organs concerned with reproduction. consider splitting genitalia from reproductive system + Anatomical system which consists of organs and tissues associated with sexual reproduction of the organism.[AAO] Arguably, one of the most important aspects of urbilaterian organogenesis would have been gonadogenesis, since Urbilateria must have successfully generated gametes and developed a strategy for extrusion and fertilization, in order to be the ancestor of all living Bilateria.[well established][VHOG] @@ -34237,6 +34283,7 @@ For example, A and B may be gene products and binding of B by A positively regul HAO:0000374 HAO:0000895 MA:0000326 + MESH:D005835 MIAA:0000305 NCIT:C12841 SCTID:278875001 @@ -34260,6 +34307,7 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0000990 + @@ -34291,6 +34339,19 @@ For example, A and B may be gene products and binding of B by A positively regul PMID:21672850 Extavour CGM, Gray anatomy: phylogenetic patterns of somatic gonad structures and reproductive strategies across Bilateria. Integrative and Comparative Biology (2007) http://bgee.unil.ch/ + + + + FBbt:00004857 + + + + + + MESH:D005835 + + https://github.com/biopragmatics/biomappings + @@ -34332,7 +34393,7 @@ For example, A and B may be gene products and binding of B by A positively regul systemata genitalia Wikipedia:Reproductive_system - + @@ -34450,6 +34511,12 @@ For example, A and B may be gene products and binding of B by A positively regul FMA xref is a 'general anatomical term' FMA + + + + FBbt:00004858 + + @@ -34562,6 +34629,12 @@ For example, A and B may be gene products and binding of B by A positively regul many anatomy ontologies consider gastrointestinal system synonymous with digestive system. here we follow MA in dividing digestive system into gastrointestinal and hepatobiliary. hepatobiliary includes the liver and biliary tract. species-specific AO classes are categorized according to whether liver is included. For example, XAO includes liver as part of XAO:0000125 alimentary system, so we assume this class is the more generic class MA + + + + FBbt:00005055 + + @@ -34701,6 +34774,12 @@ For example, A and B may be gene products and binding of B by A positively regul This definition is inclusive of the organs of the vertebrate renal system, as well as the Malpighian tubules of insects, and allows for future incorporation of structures such as the antennal glands of crustaceans DOI:10.1371/journal.pone.0099864 + + + + FBbt:00005056 + + @@ -34766,6 +34845,7 @@ For example, A and B may be gene products and binding of B by A positively regul We should divest ourselves of the view that earlier vertebrate groups were 'on their way' to becoming mammals, as clearly they were not such visionaries. Neither were their systems 'imperfect' as earlier anatomists thought. Instead, their circulatory systems served them well to address the ecological demands arising from their lifestyles.[well established][VHOG] AAO:0000959 CALOHA:TS-2103 + MESH:D002319 VHOG:0001248 Wikipedia:Circulatory_system uberon @@ -34813,12 +34893,19 @@ For example, A and B may be gene products and binding of B by A positively regul ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.493 http://bgee.unil.ch/ + + + + MESH:D002319 + + https://github.com/biopragmatics/biomappings + systema cardiovasculare Wikipedia:Circulatory_system - + @@ -34899,7 +34986,7 @@ For example, A and B may be gene products and binding of B by A positively regul musculi FMA:32558 FMA:TA - + @@ -34950,13 +35037,14 @@ For example, A and B may be gene products and binding of B by A positively regul - + The nervous system is an organ system containing predominantly neuron and glial cells. In bilaterally symmetrical organism, it is arranged in a network of tree-like structures connected to a central body. The main functions of the nervous system are to regulate and control body functions, and to receive sensory input, process this information, and generate behavior [CUMBO]. + A regulatory system of the body that consists of neurons and neuroglial cells. The nervous system is divided into two parts, the central nervous system (CNS) and the peripheral nervous system (PNS). (Source: BioGlossary, www.Biology-Text.com)[TAO] Anatomical system consisting of nerve bodies and nerve fibers which regulate the response of the body to external and internal stimuli.[AAO] Nervous systems evolved in the ancestor of Eumetazoa.[well established][VHOG] @@ -34996,6 +35084,7 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0001016 + @@ -35003,14 +35092,14 @@ For example, A and B may be gene products and binding of B by A positively regul http://upload.wikimedia.org/wikipedia/commons/b/b2/TE-Nervous_system_diagram.svg http://upload.wikimedia.org/wikipedia/commons/b/ba/Nervous_system_diagram.png - + - + Bgee:AN @@ -35053,6 +35142,12 @@ For example, A and B may be gene products and binding of B by A positively regul ISBN:978-0198566694 Schmidt-Rhaesa A, The evolution of organ systems (2007) p.117 http://bgee.unil.ch/ + + + + FBbt:00005093 + + @@ -35076,7 +35171,7 @@ For example, A and B may be gene products and binding of B by A positively regul systema nervosum Wikipedia:Nervous_system - + @@ -35098,9 +35193,10 @@ For example, A and B may be gene products and binding of B by A positively regul - + The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the neural tube derivatives: the brain and spinal cord. In invertebrates it includes central ganglia plus nerve cord. + Part of the nervous system which includes the brain and spinal cord.[AAO] The brain and spinal cord. Kimmel et al, 1995.[TAO] The central nervous system (CNS) is the part of the nervous system which includes the brain, spinal cord, and nerve cell layer of the retina (CUMBO). @@ -35140,12 +35236,13 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0001017 + central nervous system - + @@ -35159,7 +35256,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Bgee:AN @@ -35210,6 +35307,12 @@ For example, A and B may be gene products and binding of B by A positively regul ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.28 (reference 1), ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.165 (reference 2), DOI:10.1016/j.cell.2007.02.040 Denes AS, Jekely G, Steinmetz PRH, Raible F, Snyman H, Prud'homme B, Ferrier DEK, Balavoine G and Arendt D, Molecular architecture of annelid nerve cord supports common origin of nervous system centralization in Bilateria. Cell (2007) (reference 3) http://bgee.unil.ch/ + + + + FBbt:00005094 + + @@ -35229,7 +35332,7 @@ For example, A and B may be gene products and binding of B by A positively regul systema nervosum centrale FMA:55675 FMA:TA - + @@ -35302,6 +35405,12 @@ For example, A and B may be gene products and binding of B by A positively regul ISBN:978-0030259821 Ruppert EE, Fox RS, Barnes RD, Invertebrate zoology: a functional evolutionary approach (2003) p.203, ISBN:978-0521617147 Stevens CE and Hume ID, Comparative physiology of the vertebrate digestive system (2004) p.11 http://bgee.unil.ch/ + + + + FBbt:00005379 + + @@ -35313,14 +35422,14 @@ For example, A and B may be gene products and binding of B by A positively regul praeenteron Wikipedia:Foregut - + proenteron Wikipedia:Foregut - + @@ -35395,6 +35504,12 @@ For example, A and B may be gene products and binding of B by A positively regul in FMA this represents an embryonic region. FMA + + + + FBbt:00005383 + + @@ -35406,7 +35521,7 @@ For example, A and B may be gene products and binding of B by A positively regul mesenteron Wikipedia:Midgut - + @@ -35415,7 +35530,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -35452,14 +35567,14 @@ For example, A and B may be gene products and binding of B by A positively regul hindgut http://upload.wikimedia.org/wikipedia/commons/f/f7/Gray472.png - + - + Wikipedia @@ -35490,6 +35605,12 @@ For example, A and B may be gene products and binding of B by A positively regul in FMA this class has no children. In MA it has a single child hindgut epithelium FMA + + + + FBbt:00005384 + + @@ -35501,7 +35622,7 @@ For example, A and B may be gene products and binding of B by A positively regul metenteron Wikipedia:Hindgut - + @@ -35555,6 +35676,12 @@ For example, A and B may be gene products and binding of B by A positively regul FB:FBrf0089570 http://flybase.org/reports/FBrf0178740.html + + + + FBbt:00005495 + + @@ -35675,6 +35802,14 @@ For example, A and B may be gene products and binding of B by A positively regul The mature structure of the neural tube exists when the tube has been segmented into the forebrain, midbrain, hindbrain and spinal cord regions. In addition neural crest has budded away from the epithelium GO:0021915 + + + + MESH:D054259 + + + https://github.com/biopragmatics/biomappings + @@ -35686,7 +35821,7 @@ For example, A and B may be gene products and binding of B by A positively regul tubus neuralis Wikipedia:Neural_tube - + @@ -35729,6 +35864,12 @@ For example, A and B may be gene products and binding of B by A positively regul FMA:62955 http://orcid.org/0000-0001-9114-8737 + + + + FBbt:10000000 + + @@ -35857,7 +35998,7 @@ For example, A and B may be gene products and binding of B by A positively regul vena cava inferior BTO:0002682 Wikipedia:Inferior_vena_cava - + @@ -36024,7 +36165,7 @@ For example, A and B may be gene products and binding of B by A positively regul venae renales Wikipedia:Renal_vein - + @@ -36034,14 +36175,14 @@ For example, A and B may be gene products and binding of B by A positively regul - + - + @@ -36093,24 +36234,24 @@ For example, A and B may be gene products and binding of B by A positively regul renal pelvis https://upload.wikimedia.org/wikipedia/commons/c/c0/Illu_kidney2.jpg - + - + - + MA - + FMA @@ -36130,7 +36271,7 @@ For example, A and B may be gene products and binding of B by A positively regul p. renallis Wikipedia:Renal_pelvis - + @@ -36156,7 +36297,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -36193,14 +36334,14 @@ For example, A and B may be gene products and binding of B by A positively regul https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Kidney_R.glb https://upload.wikimedia.org/wikipedia/commons/6/69/Illu_kidney.jpg - + - + FMA @@ -36221,7 +36362,7 @@ For example, A and B may be gene products and binding of B by A positively regul cortex renalis FMA:15581 FMA:TA - + @@ -36236,7 +36377,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -36284,14 +36425,14 @@ For example, A and B may be gene products and binding of B by A positively regul renal corpuscle https://upload.wikimedia.org/wikipedia/commons/2/22/Renal_corpuscle.svg - + - + MA ZFA @@ -36352,14 +36493,14 @@ For example, A and B may be gene products and binding of B by A positively regul corpusculum renale - + corpusculum renis Wikipedia:Renal_corpuscle - + @@ -36392,7 +36533,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -36437,14 +36578,14 @@ For example, A and B may be gene products and binding of B by A positively regul glomerular capsule http://upload.wikimedia.org/wikipedia/commons/3/30/Gray1130.svg - + - + Wikipedia @@ -36486,7 +36627,7 @@ For example, A and B may be gene products and binding of B by A positively regul capsula glomerularis - + @@ -36529,7 +36670,7 @@ For example, A and B may be gene products and binding of B by A positively regul capsula glomeruli - + @@ -36543,11 +36684,11 @@ For example, A and B may be gene products and binding of B by A positively regul - + - - + + @@ -36586,7 +36727,7 @@ For example, A and B may be gene products and binding of B by A positively regul nephron tubule - + @@ -36595,18 +36736,18 @@ For example, A and B may be gene products and binding of B by A positively regul - + - + - + GO MA ZFA @@ -36620,13 +36761,13 @@ For example, A and B may be gene products and binding of B by A positively regul - + ZFA - + checkme @@ -36667,7 +36808,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -36715,14 +36856,14 @@ For example, A and B may be gene products and binding of B by A positively regul collecting duct of renal tubule - + - + checkme GO @@ -36765,7 +36906,7 @@ For example, A and B may be gene products and binding of B by A positively regul tubulus renalis arcuatus Wikipedia:Connecting_tubule - + @@ -36867,6 +37008,12 @@ For example, A and B may be gene products and binding of B by A positively regul Wikipedia:Anus ZFIN:curator + + + + FBbt:00047153 + + @@ -36882,8 +37029,8 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + Distensible musculomembranous organ situated in the anterior part of the pelvic cavity in which urine collects before excretion[MP]. @@ -36930,11 +37077,11 @@ For example, A and B may be gene products and binding of B by A positively regul https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Urinary_Bladder.glb https://upload.wikimedia.org/wikipedia/commons/3/30/Urinary_system.svg - + - + @@ -36947,13 +37094,13 @@ For example, A and B may be gene products and binding of B by A positively regul - + FMA - + upper part of UG sinus @@ -37016,7 +37163,7 @@ For example, A and B may be gene products and binding of B by A positively regul vesica urinaria Wikipedia:Urinary_bladder - + @@ -37136,15 +37283,15 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + - + The basic functional unit of the kidney. its chief function is to regulate the concentration of water and soluble substances like sodium salts by filtering the blood, reabsorbing what is needed and excreting the rest as urine. A nephron eliminates wastes from the body, regulates blood volume and blood pressure, controls levels of electrolytes and metabolites, and regulates blood pH. Its functions are vital to life and are regulated by the endocrine system by hormones such as antidiuretic hormone, aldosterone, and parathyroid hormone.[WP]. kidney terms require review for cross-vertebrate compatibility and developmental relationships. @@ -37177,34 +37324,34 @@ For example, A and B may be gene products and binding of B by A positively regul nephron http://upload.wikimedia.org/wikipedia/commons/0/02/Gray1128.png - + - + - + - + FMA - + definitional - + Bgee:AN @@ -37246,14 +37393,14 @@ For example, A and B may be gene products and binding of B by A positively regul nephroneum Wikipedia:Nephron - + tubulus renalis Wikipedia:Nephron - + @@ -37264,15 +37411,15 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + - + @@ -37309,15 +37456,15 @@ For example, A and B may be gene products and binding of B by A positively regul proximal convoluted tubule http://upload.wikimedia.org/wikipedia/commons/0/02/Gray1128.png - + - + - + @@ -37330,20 +37477,20 @@ For example, A and B may be gene products and binding of B by A positively regul - + MA uses subclass GOC:mtg_kidney_jan10 - + GO - + Wikipedia @@ -37384,13 +37531,13 @@ For example, A and B may be gene products and binding of B by A positively regul tubulus contortus proximalis Wikipedia:Proximal_convoluted_tubule - + tubulus convolutus proximalis - + @@ -37500,7 +37647,7 @@ For example, A and B may be gene products and binding of B by A positively regul ansa nephroni Wikipedia:Loop_of_Henle - + @@ -37509,7 +37656,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -37536,7 +37683,7 @@ For example, A and B may be gene products and binding of B by A positively regul descending limb of loop of Henle http://upload.wikimedia.org/wikipedia/commons/0/02/Gray1128.png - + @@ -37549,7 +37696,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + FMA @@ -37573,9 +37720,9 @@ For example, A and B may be gene products and binding of B by A positively regul - - - + + + @@ -37615,15 +37762,15 @@ For example, A and B may be gene products and binding of B by A positively regul proximal straight tubule - + - + - + @@ -37636,20 +37783,20 @@ For example, A and B may be gene products and binding of B by A positively regul - + MA - + MA uses subclass GOC:mtg_kidney_jan10 - + MA @@ -37700,7 +37847,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -37738,7 +37885,7 @@ For example, A and B may be gene products and binding of B by A positively regul distal convoluted tubule https://upload.wikimedia.org/wikipedia/commons/2/21/Kidney_nephron.png - + @@ -37751,7 +37898,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + EMAPA GO MA-modified-from-isa @@ -37779,13 +37926,13 @@ For example, A and B may be gene products and binding of B by A positively regul tubulus contortus distalis Wikipedia:Distal_convoluted_tubule - + tubulus convolutus distalis - + @@ -37844,7 +37991,7 @@ For example, A and B may be gene products and binding of B by A positively regul zona externa (medullaris renalis) FMA:17733 FMA:TA - + @@ -37852,7 +37999,7 @@ For example, A and B may be gene products and binding of B by A positively regul zona externa medullae renalis FMA:17733 FMA:TA - + @@ -37879,7 +38026,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + The anus and surrounding regions. Encompasses both internal and external regions, where present. Although all vertebrates have a digestive tract and accessory glands, various parts of this system are not necessarily homologous, analogous, or even present in all species. Therefore, broad comparisons can be best made under the listings of headgut, foregut, midgut, pancreas and biliary system, hindgut.[uncertain][VHOG] EFO:0000847 @@ -37905,14 +38052,14 @@ For example, A and B may be gene products and binding of B by A positively regul https://github.com/obophenotype/uberon/issues/507 http://upload.wikimedia.org/wikipedia/commons/f/fb/Gray408.png - + - + cjm @@ -38099,7 +38246,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -38122,14 +38269,14 @@ For example, A and B may be gene products and binding of B by A positively regul kidney arcuate artery https://upload.wikimedia.org/wikipedia/commons/8/87/2610_The_Kidney.jpg - + - + MA @@ -38170,7 +38317,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + A tube extending from the mouth to the anus. @@ -38191,6 +38338,7 @@ For example, A and B may be gene products and binding of B by A positively regul FBbt:00003125 FMA:45615 MA:0000917 + MESH:D041981 NCIT:C34082 TAO:0000112 TGMA:0001819 @@ -38212,14 +38360,14 @@ For example, A and B may be gene products and binding of B by A positively regul digestive tract - + - + NCBIBook:NBK10107 @@ -38272,6 +38420,19 @@ For example, A and B may be gene products and binding of B by A positively regul we place the MA and EMAPA class here, although the intent is probably a smaller region. See https://github.com/obophenotype/uberon/issues/509 MA + + + + FBbt:00003125 + + + + + + MESH:D041981 + + https://github.com/biopragmatics/biomappings + @@ -38316,12 +38477,14 @@ For example, A and B may be gene products and binding of B by A positively regul Subdivision of urinary system which consists of the urinary bladder and the urethra. + FMA:45659 MA:0002636 SCTID:181420004 galen:LowerUrinaryTract uberon UBERON:0001556 + lower urinary tract @@ -38637,7 +38800,7 @@ For example, A and B may be gene products and binding of B by A positively regul vena Wikipedia:Vein - + @@ -38864,7 +39027,7 @@ For example, A and B may be gene products and binding of B by A positively regul venula Wikipedia:Venule - + @@ -38973,7 +39136,7 @@ For example, A and B may be gene products and binding of B by A positively regul arteriola Wikipedia:Arteriole - + @@ -38989,8 +39152,8 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + @@ -39003,7 +39166,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -39062,34 +39225,34 @@ For example, A and B may be gene products and binding of B by A positively regul blood vessel http://upload.wikimedia.org/wikipedia/commons/2/29/Circulatory_System_en.svg - + - + - + - + AEO - + EHDAA2 - + GO:0072360 @@ -39162,7 +39325,7 @@ For example, A and B may be gene products and binding of B by A positively regul vas sanguineum Wikipedia:Blood_vessel - + @@ -39499,6 +39662,12 @@ For example, A and B may be gene products and binding of B by A positively regul in FMA embryo is_a embryonic structure FMA + + + + FBbt:00004208 + + @@ -39741,7 +39910,7 @@ For example, A and B may be gene products and binding of B by A positively regul atrium dextrum Wikipedia:Right_atrium - + @@ -39907,6 +40076,7 @@ For example, A and B may be gene products and binding of B by A positively regul FMA:71221 MA:0002986 MAT:0000148 + MESH:D013131 MIAA:0000148 TAO:0000317 VHOG:0000317 @@ -39982,6 +40152,13 @@ For example, A and B may be gene products and binding of B by A positively regul EMAPA:37721 MA:th + + + + MESH:D013131 + + https://github.com/biopragmatics/biomappings + @@ -40113,7 +40290,7 @@ For example, A and B may be gene products and binding of B by A positively regul skeleton appendiculare Wikipedia:Appendicular_skeleton - + @@ -40225,7 +40402,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -40238,7 +40415,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -40287,24 +40464,24 @@ For example, A and B may be gene products and binding of B by A positively regul kidney - + - + - + FMA - + definitional @@ -40345,8 +40522,8 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + @@ -40390,11 +40567,11 @@ For example, A and B may be gene products and binding of B by A positively regul Once the more complex mesonephros forms the pronephros undergoes apoptosis in amphibians. In fishes the nephron degenerates but the organ remains and becomes a component of the immune system[Wikipedia:Pronephros]. // TODO - check developmental relationships. Note that we previously include the ZFA/XAO terms under the more specific 'pronephric kidney', but these are now merged. TODO GCI: relationship: capable_of GO:0030104 pronephros - + - + @@ -40407,13 +40584,13 @@ For example, A and B may be gene products and binding of B by A positively regul - + OG - + ZFA @@ -40460,6 +40637,14 @@ For example, A and B may be gene products and binding of B by A positively regul ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.637 http://bgee.unil.ch/ + + + + MESH:D060910 + + + https://github.com/biopragmatics/biomappings + @@ -40635,7 +40820,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -40669,14 +40854,14 @@ For example, A and B may be gene products and binding of B by A positively regul musculoskeletal system - + - + check ctenophore @@ -40790,7 +40975,7 @@ For example, A and B may be gene products and binding of B by A positively regul cavitas thoracis Wikipedia:Thoracic_cavity - + @@ -40806,7 +40991,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -40825,7 +41010,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + An anatomical structure which consists of juxtaglomerular cells, extraglomerular mesangial cells and the macula densa. The juxtaglomerular apparatus lies adjacent to the glomerulus and regulates kidney function by maintaining the blood flow to the kidney and the filtration rate[GO]. a microscopic structure in the kidney, which regulates the function of each nephron. The juxtaglomerular apparatus is named for its proximity to the glomerulus: it is found between the vascular pole of the renal corpuscle and the returning distal convoluted tubule of the same nephron. This location is critical to its function in regulating renal blood flow and glomerular filtration rate. The three cellular components of the apparatus are the macula densa, extraglomerular mesangial cells, and juxtaglomerular cells (also known as granular cells)[WP]. BTO:0005157 @@ -40847,24 +41032,24 @@ For example, A and B may be gene products and binding of B by A positively regul juxtaglomerular apparatus - + - + - + MA - + GO @@ -40884,7 +41069,7 @@ For example, A and B may be gene products and binding of B by A positively regul complexus juxtaglomerularis - + @@ -40995,8 +41180,8 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + @@ -41013,24 +41198,24 @@ For example, A and B may be gene products and binding of B by A positively regul EDITOR_NOTE check MA part_ofs - should be spatially disjoint from renal glomerulus? extraglomerular mesangium - + - + - + MA - + MA @@ -41047,7 +41232,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -41088,14 +41273,14 @@ For example, A and B may be gene products and binding of B by A positively regul EDITOR_NOTE check the FMA placement here; ncit placement of body cavity here probably not correct coelemic cavity lumen - + - + definitional @@ -41128,6 +41313,12 @@ For example, A and B may be gene products and binding of B by A positively regul body cavity BTO:0001707 + + + + FBbt:00005060 + + @@ -41203,9 +41394,9 @@ For example, A and B may be gene products and binding of B by A positively regul - - - + + + @@ -41260,15 +41451,15 @@ For example, A and B may be gene products and binding of B by A positively regul notochord http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + - + - + @@ -41287,19 +41478,19 @@ For example, A and B may be gene products and binding of B by A positively regul - + http://tolweb.org/Chordata/2499 - + ZFA - + EHDAA2 @@ -41374,7 +41565,7 @@ For example, A and B may be gene products and binding of B by A positively regul notochorda Wikipedia:Notochord - + @@ -41384,8 +41575,8 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + Somites are spheres of epithelial cells that form sequentially along the anterior-posterior axis of the embryo through mesenchymal to epithelial transition of the presomitic mesoderm. EDITOR_NOTE currently classified as an epithelial vesicle, consistent with EHDAA2 and https://github.com/obophenotype/uberon/wiki/The-neural-crest. Consider making 'somitic mesoderm' a separate term and correlate with regionalization processes. Consider moving ZFA term to 'trunk somite' as it is part of the trunk @@ -41431,11 +41622,11 @@ For example, A and B may be gene products and binding of B by A positively regul somite http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + - + @@ -41448,13 +41639,13 @@ For example, A and B may be gene products and binding of B by A positively regul - + GOTAX:0000352 - + ZFA @@ -41557,7 +41748,7 @@ For example, A and B may be gene products and binding of B by A positively regul somitus Wikipedia:Somite - + @@ -41566,8 +41757,8 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + The macula densa is an area of specialized cells in the distal tubule that makes contact with the vascular pole of the glomerulus[GO]. not part of a nephron or distal tubule in MA and FMA @@ -41586,24 +41777,24 @@ For example, A and B may be gene products and binding of B by A positively regul macula densa - + - + - + MA - + GO @@ -41633,12 +41824,12 @@ For example, A and B may be gene products and binding of B by A positively regul - - - - - - + + + + + + A specialized region of ectoderm found between the neural ectoderm (neural plate) and non-neural ectoderm and composed of highly migratory pluripotent cells that delaminate in early embryonic development from the dorsal neural tube and give rise to an astounding variety of differentiated cell types[MP]. EDITOR_NOTE consider including subclasses for pre- and post- migratory (e.g. sheets/paths/streams). @@ -41678,66 +41869,66 @@ For example, A and B may be gene products and binding of B by A positively regul http://upload.wikimedia.org/wikipedia/commons/5/5f/Gray644.png https://upload.wikimedia.org/wikipedia/commons/8/8f/Neural_Crest.png - + - + - + - + - + - + - + XAO https://github.com/obophenotype/uberon/wiki/The-neural-crest - + Hall and others restrict NC to vertebrates but we opt for a less restrictive constraint to avoid inconsistencies when areas such as P1 area of pallium in hagfishes inherit cell lineage from telecephalon-contributing NC cells ISBN:0073040584 - + BTO - + PMID:11523831 - + pre migratory https://github.com/obophenotype/uberon/wiki/The-neural-crest - + PMID:11523831 @@ -41805,7 +41996,7 @@ For example, A and B may be gene products and binding of B by A positively regul crista neuralis Wikipedia:Neural_crest - + @@ -41878,6 +42069,12 @@ For example, A and B may be gene products and binding of B by A positively regul DOI:10.1046/j.1469-7580.2001.19910133.x Graham A. The development and evolution of the pharyngeal arches. J Anat (2001) http://bgee.unil.ch/ + + + + FBbt:00001057 + + @@ -41889,7 +42086,7 @@ For example, A and B may be gene products and binding of B by A positively regul epithelium tubi neuralis; neuroectoderma Wikipedia:Neuroectoderm - + @@ -42206,14 +42403,14 @@ For example, A and B may be gene products and binding of B by A positively regul - + - + Anatomical system that is involved in the production of hematopoietic cells. @@ -42258,24 +42455,24 @@ For example, A and B may be gene products and binding of B by A positively regul hematopoietic system - + - + - + FMA - + definitional @@ -42449,7 +42646,7 @@ For example, A and B may be gene products and binding of B by A positively regul epiblastus Wikipedia:Epiblast - + @@ -42529,7 +42726,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Unsegmented field of paraxial mesoderm present posterior to the most recently formed somite pair, from which somites will form. Unsegmented field of paraxial mesoderm present posterior to the most recently formed somite pair, from which somites will form. Kimmel et al, 1995.[TAO] It is reasonable to assume that the proximate invertebrate ancestor of the vertebrates had an amphioxus-like tail bud in its larval stage. This archetypal tail bud would have (...) (3) lacked any component of mesenchyme cells, (4) budded off new mesodermal segments directly, without any intervening zone of presomitic mesoderm (...). Then, early in vertebrate evolution, epithelium-to-mesenchyme interconversions (and the gene networks for effecting them) became prominent features of development. (...) In any case, conspicuous mesenchymal components tended to be added to the vertebrate tail bud itself. In addition, a mesenchymatous presomitic mesoderm (not a part of the tail bud proper) came to intervene between the tail bud and the forming somites.[well established][VHOG] @@ -42554,14 +42751,14 @@ For example, A and B may be gene products and binding of B by A positively regul presomitic mesoderm - + - + Bgee:AN @@ -42621,8 +42818,8 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + In mammals, the pronephric duct is the predecessor of the Wolffian duct[WP]. Duct of the embryonic kidney, present bilaterally ventral to the somites and leading to the anal region where it empties separately from, and just posterior to the anus. Kimmel et al, 1995.[TAO] The first-formed kidney duct, which drains the kidney of most anamniotes and becomes the ductus deferens of male amniotes. [Bemis_WE, Functional_Anatomy_of_the_Vertebrates:_An_Evolutionary_Perspective, Glossary_G-3, Grande_L, Liem_KF, Third_Edition_(2001)_Orlando_Fla.:_Harcourt_College_Publishers, Walker_WF][VHOG] @@ -42646,11 +42843,11 @@ For example, A and B may be gene products and binding of B by A positively regul The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the pronephric kidney[GOC:mtg_kidney_jan10, PMID:15647339, XAO:0000063, ZFA:0000150] pronephric duct - + - + @@ -42663,13 +42860,13 @@ For example, A and B may be gene products and binding of B by A positively regul - + Wikipedia - + XAO @@ -42710,7 +42907,9 @@ For example, A and B may be gene products and binding of B by A positively regul BTO:0005991 - https://orcid.org/0000-0003-4423-4370 + + + https://github.com/biopragmatics/biomappings @@ -42729,7 +42928,7 @@ For example, A and B may be gene products and binding of B by A positively regul ductus pronephricus Wikipedia:Pronephric_duct - + @@ -42856,9 +43055,9 @@ For example, A and B may be gene products and binding of B by A positively regul - - - + + + @@ -42900,34 +43099,34 @@ For example, A and B may be gene products and binding of B by A positively regul intermediate mesoderm http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + - + - + - + AAO - + EMAPA - + XAO @@ -42991,7 +43190,7 @@ For example, A and B may be gene products and binding of B by A positively regul mesenchyma intermedium Wikipedia:Intermediate_mesoderm - + @@ -43072,7 +43271,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Paired organ that connects the primitive kidney Wolffian body (or mesonephros) to the cloaca and serves as the anlage for certain male reproductive organs. the Wolffian duct is what remains of the pronephric duct after the atrophy of the pronephros[WP]. In Zebrafish: Duct of the adult kidney (mesonephros), present bilaterally ventral to the somites and leading to the cloacal chamber[ZFA]. Consider adding subclasses for male and female specific variants TODO - mesonephric portion of the nephric duct @@ -43108,7 +43307,7 @@ For example, A and B may be gene products and binding of B by A positively regul mesonephric duct http://upload.wikimedia.org/wikipedia/commons/6/6d/Gray1109.png - + @@ -43121,7 +43320,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + EHDAA2 @@ -43164,7 +43363,9 @@ For example, A and B may be gene products and binding of B by A positively regul BTO:0005990 - https://orcid.org/0000-0003-4423-4370 + + + https://github.com/biopragmatics/biomappings @@ -43198,7 +43399,7 @@ For example, A and B may be gene products and binding of B by A positively regul ductus mesonephricus; ductus Wolffi Wikipedia:Mesonephric_duct - + @@ -43209,9 +43410,9 @@ For example, A and B may be gene products and binding of B by A positively regul - - - + + + A region of embryonic ectodermal cells that lie directly above the notochord. During neurulation, they change shape and produce an infolding of the neural plate (the neural fold) that then seals to form the neural tube[XAO]. The earliest recognizable dorsal ectodermal primordium of the central nervous system present near the end of gastrulation before infolding to form the neural keel; consists of a thickened pseudostratified epithelium[ZFA]. The earliest recognizable dorsal ectodermal primordium of the central nervous system present near the end of gastrulation before infolding to form the neural keel; consists of a thickened pseudostratified epithelium. Kimmel et al, 1995.[TAO] (...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord that is located dorsal to the notochord (...).[well established][VHOG] @@ -43243,34 +43444,34 @@ For example, A and B may be gene products and binding of B by A positively regul neural plate https://upload.wikimedia.org/wikipedia/commons/8/8f/Neural_Crest.png - + - + - + - + GOTAX:0000352 - + Wikipedia - + Bgee:AN @@ -43301,6 +43502,14 @@ For example, A and B may be gene products and binding of B by A positively regul ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.28 http://bgee.unil.ch/ + + + + MESH:D054258 + + + https://github.com/biopragmatics/biomappings + @@ -43312,7 +43521,7 @@ For example, A and B may be gene products and binding of B by A positively regul lamina neuralis Wikipedia:Neural_plate - + @@ -43335,7 +43544,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube[GO]. Mesoderm lateral to the neural tube and notochord that is divided into cranial and post-cranial portions. The trunk portions further segment into somites.[AAO] Presently, Cephalochordata, Urochordata, and Vertebrata are placed as subphyla of the phylum Chordata, in which the overall organization of embryonic tissues (dorsal hollow nerve cord, ventral digestive tract, axial notochord, and bilateral paraxial mesoderm) is largely conserved. In contrast, the echinoderms and hemichordates are sister groups of the chordates and they lack the notochord and paraxial mesoderm. Thus, the basic mesodermal organization of vertebrates must have appeared first in the common ancestor of the chordates.[well established][VHOG] @@ -43364,7 +43573,7 @@ For example, A and B may be gene products and binding of B by A positively regul paraxial mesoderm http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + @@ -43377,7 +43586,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Bgee:AN @@ -43437,7 +43646,7 @@ For example, A and B may be gene products and binding of B by A positively regul mesoderma paraxiale Wikipedia:Paraxial_mesoderm - + @@ -43449,7 +43658,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -43493,7 +43702,7 @@ For example, A and B may be gene products and binding of B by A positively regul lateral plate mesoderm http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + @@ -43506,7 +43715,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + EHDAA2 VHOG @@ -43581,7 +43790,7 @@ For example, A and B may be gene products and binding of B by A positively regul mesoderma laminae lateralis Wikipedia:Lateral_plate_mesoderm - + @@ -43590,15 +43799,15 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + - + Bilateral groups of cells consisting of three rows: one row of endocardial precursors medially and two rows of myocardical precursors laterally. The two populations fuse at the midline to form the heart rudiment or cone. should probably be merged with heart rudiment. Bilateral groups of cells consisting of three rows: one row of endocardial precursors medially and two rows of myocardical precursors laterally. The two populations fuse at the midline between 21 and 26 somites to form the heart rudiment or cone. Stainier 2001.[TAO] @@ -43618,15 +43827,15 @@ For example, A and B may be gene products and binding of B by A positively regul heart primordium - + - + - + @@ -43639,19 +43848,19 @@ For example, A and B may be gene products and binding of B by A positively regul - + ZFA - + ZFA - + XAO @@ -43706,8 +43915,8 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + Ventral somitic compartment that is a precursor of the axial skeleton[XAO]. Sclerotomes eventually differentiate into the vertebrae and most of the skull. The caudal (posterior) half of one sclerotome fuses with the rostral (anterior) half of the adjacent one to form each vertebra. From their initial location within the somite, the sclerotome cells migrate medially towards the notochord. These cells meet the sclerotome cells from the other side to form the vertebral body. From this vertebral body, sclerotome cells move dorsally and surround the developing spinal cord, forming the vertebral arch[WP]. Skeletogenic portion of somites.[AAO] The vertebrate sclerotome has no equivalent in amphioxus and is a novelty linked with the evolution of the axial skeleton.[well established][VHOG] @@ -43735,11 +43944,11 @@ For example, A and B may be gene products and binding of B by A positively regul sclerotome http://upload.wikimedia.org/wikipedia/commons/9/96/Gray65.png - + - + @@ -43758,13 +43967,13 @@ For example, A and B may be gene products and binding of B by A positively regul - + VHOG:0000680 - + ZFA @@ -43804,7 +44013,9 @@ For example, A and B may be gene products and binding of B by A positively regul BTO:0006255 - https://orcid.org/0000-0003-4423-4370 + + + https://github.com/biopragmatics/biomappings @@ -43824,7 +44035,7 @@ For example, A and B may be gene products and binding of B by A positively regul sclerotomus Wikipedia:Sclerotome - + @@ -43964,7 +44175,7 @@ For example, A and B may be gene products and binding of B by A positively regul mesenchyma Wikipedia:Mesenchyme - + @@ -44070,7 +44281,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -44098,14 +44309,14 @@ For example, A and B may be gene products and binding of B by A positively regul Genes: The positional specification of the metanephrogenic mesenchyme is negatively regulated by Foxc1 and Foxc2. Next the permanent kidney forming metanephrogenic mesenchyme is specified by Hox11 genes. The competence to respond to ureteric bud inducers is regulated by WT1. GDNF secretion restricted to posterior region by Robo2 and Sprouty1. The receptors for GDNF are synthesized in the nephric ducts and later in ureteric buds [ISBN:9780878932504 "Developmental Biology"] metanephric mesenchyme - + - + ISBN:9780878932504 @@ -44821,7 +45032,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + The part of the coelom in the embryo between the somatopleuric and splanchnopleuric mesoderm; the principal body cavities of the trunk (thoracic, abdominal, and pelvic) arise from this embryonic part of the coelom. consider merging with coelom. TODO - add spatial relationships to halves of LPM. Note the OG places XAO and ZFA coelem terms here. editor note: TODO check ZFA, which appears to be a structure present in adults (...) I regard it unlikely that coeloms of all bilaterian animals are comparable and evolved very early. Considering all these questions, few convincing characters concerning the evolution of body cavities remain to be named. (...) A segmental coelom appears to have evolved at least two times, in Annelida and in Myomerata (Acrania and Craniota).[well established][VHOG] @@ -44837,14 +45048,14 @@ For example, A and B may be gene products and binding of B by A positively regul intraembryonic coelom - + - + Wikipedia @@ -44954,6 +45165,12 @@ For example, A and B may be gene products and binding of B by A positively regul GO:0060562 PMID:12526790 + + + + FBbt:00007474 + + @@ -45150,7 +45367,7 @@ For example, A and B may be gene products and binding of B by A positively regul tubulus renalis colligens Wikipedia:Collecting_duct_system - + @@ -45471,8 +45688,8 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + In mammals, the proximal tubule is a nephron tubule that connects Bowman's capsule to the loop of Henle. It has a brush border epithelial morphology[GO]. TODO - ensure definition works across species. @@ -45489,24 +45706,24 @@ For example, A and B may be gene products and binding of B by A positively regul proximal tubule - + - + - + GO - + GO @@ -45566,7 +45783,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + The intermediate tubule is a nephron tubule that lies between the proximal and distal tubules. TODO - check for applicability across species FMA:17718 @@ -45576,14 +45793,14 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0004136 intermediate tubule - + - + FMA @@ -45669,8 +45886,8 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + A specific region of the lateral mesoderm that will form the primary beating heart tube. In mammals the primary heart field gives rise to the left ventricle. this term denotes the primary heart field; GO:0003128 denotes the superclass of primary and secondary: specific region of the lateral mesoderm into the area which will form the primary beating heart tube[GO:0003138] XAO:0004185 @@ -45683,24 +45900,24 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0004140 primary heart field - + - + - + GO:0003128 - + https://orcid.org/0000-0003-3308-6245 @@ -45759,7 +45976,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + An epithelial tube that will give rise to the mature heart. the paired, longitudinal, endothelial-lined channels formed from the cardiogenic mesoderm in embryonic development; angiogenic cell clusters (aka angioblastic cords) located in a horse-shoe shape configuration in the cardiogenic plate coalesce to form the right and left endocardial heart tubes which then fuse in cephalo-caudal direction to form a single primitive heart tube. AAO:0010411 @@ -45779,14 +45996,14 @@ For example, A and B may be gene products and binding of B by A positively regul heart tube - + - + ZFA-modified @@ -46012,8 +46229,8 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + The comma-shaped body is the precursor structure to the S-shaped body that contributes to the morphogenesis of the nephron. EMAPA:27681 ZFA:0005588 @@ -46023,24 +46240,24 @@ For example, A and B may be gene products and binding of B by A positively regul comma-shaped body - + - + - + cjm - + ZFA @@ -46062,11 +46279,12 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + The S-shaped body is the successor of the comma-shaped body that contributes to the morphogenesis of the nephron. TODO EMAPA:27756 + VO:0010896 ZFA:0005589 SSB stage II nephron @@ -46075,24 +46293,24 @@ For example, A and B may be gene products and binding of B by A positively regul S-shaped body - + - + - + cjm - + GO @@ -46101,6 +46319,14 @@ For example, A and B may be gene products and binding of B by A positively regul The S-shaped body is the successor of the comma-shaped body that contributes to the morphogenesis of the nephron. GO:0072050 + + + + VO:0010896 + + + https://github.com/biopragmatics/biomappings + @@ -46237,7 +46463,7 @@ For example, A and B may be gene products and binding of B by A positively regul pyramides renales Wikipedia:Renal_pyramids - + @@ -46329,7 +46555,7 @@ For example, A and B may be gene products and binding of B by A positively regul stria externa medullae renalis FMA:76662 FMA:TA - + @@ -46512,7 +46738,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -46551,14 +46777,14 @@ For example, A and B may be gene products and binding of B by A positively regul glomerular capillary - + - + https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -46819,6 +47045,14 @@ For example, A and B may be gene products and binding of B by A positively regul VHOG includes a very broad grouping here based on http://www.ncbi.nlm.nih.gov/pubmed/9609826 VHOG + + + + MESH:D054240 + + + https://github.com/biopragmatics/biomappings + @@ -47141,6 +47375,7 @@ For example, A and B may be gene products and binding of B by A positively regul An endothelium that lines the blood vasculature. Other endothelia may line lymph vessels, the heart. + BTO:0000766 CALOHA:TS-2155 EMAPA:35176 @@ -47151,6 +47386,7 @@ For example, A and B may be gene products and binding of B by A positively regul ZFA:0005257 uberon UBERON:0004638 + blood vessel endothelium @@ -47188,7 +47424,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -47225,14 +47461,14 @@ For example, A and B may be gene products and binding of B by A positively regul renal afferent arteriole http://upload.wikimedia.org/wikipedia/commons/0/02/Gray1128.png - + - + Wikipedia @@ -47267,7 +47503,7 @@ For example, A and B may be gene products and binding of B by A positively regul arteriola glomerularis afferens renis FMA:77042 FMA:TA - + @@ -47280,7 +47516,7 @@ For example, A and B may be gene products and binding of B by A positively regul arteriola glomerularis afferens Wikipedia:Afferent_arterioles - + @@ -47420,14 +47656,14 @@ For example, A and B may be gene products and binding of B by A positively regul arteriae corticales radiatae Wikipedia:Interlobular_arteries - + arteriae interlobulares renis Wikipedia:Interlobular_arteries - + @@ -47520,6 +47756,12 @@ For example, A and B may be gene products and binding of B by A positively regul We explicitly merge the NCITA terms here NCIT + + + + FBbt:00005317 + + @@ -47593,7 +47835,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Organ consisting of skeletal tissue. Encompasses whole bones, fused bones, cartilaginious elements, teeth, dermal denticles. Organ entity that is typically involved in mechanical support and may have different skeletal tissue compositions at different stages.[VSAO] Organ entity that may have different tissue compositions at different stages and is typically involved in mechanical support.[TAO] @@ -47609,14 +47851,14 @@ For example, A and B may be gene products and binding of B by A positively regul skeletal element - + - + VSAO @@ -47661,7 +47903,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -47700,14 +47942,14 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0004770 articular system - + - + FMA @@ -48023,7 +48265,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -48046,14 +48288,14 @@ For example, A and B may be gene products and binding of B by A positively regul somatopleure http://upload.wikimedia.org/wikipedia/commons/2/28/Gray16.png - + - + EHDAA2 @@ -48110,7 +48352,7 @@ For example, A and B may be gene products and binding of B by A positively regul chorda nephrogenica Wikipedia:Nephrogenic_cord - + @@ -48119,9 +48361,9 @@ For example, A and B may be gene products and binding of B by A positively regul - - - + + + @@ -48142,34 +48384,34 @@ For example, A and B may be gene products and binding of B by A positively regul urogenital fold - + - + - + - + EHDAA2 - + Wikipedia - + EHDAA2 @@ -48293,6 +48535,12 @@ For example, A and B may be gene products and binding of B by A positively regul Anatomical structure that connects two or more adjacent skeletal elements or hardened body parts. http://orcid.org/0000-0002-6601-2165 + + + + FBbt:00005811 + + @@ -48345,6 +48593,12 @@ For example, A and B may be gene products and binding of B by A positively regul A proximal-distal subdivision of the digestive tract. http://orcid.org/0000-0002-6601-2165 + + + + FBbt:00100315 + + @@ -48672,28 +48926,28 @@ For example, A and B may be gene products and binding of B by A positively regul - - . + + Missing definition for term UBERON:0005095. Please replace it using linked reference. class added for consistency with GO - consider merging with kidney mesenchyme. uberon kidney anlage UBERON:0005095 kidney rudiment - + - + GO - . + Missing definition for term UBERON:0005095. Please replace it using linked reference. GO:0072003 @@ -48803,7 +49057,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + The connecting tubule is a tubular segment of the nephron; it connects the distal convoluted tubule to the collecting duct[GO]. BTO:0004539 @@ -48821,14 +49075,14 @@ For example, A and B may be gene products and binding of B by A positively regul renal connecting tubule http://upload.wikimedia.org/wikipedia/commons/0/02/Gray1128.png - + - + Wikipedia @@ -48855,7 +49109,7 @@ For example, A and B may be gene products and binding of B by A positively regul tubulus renalis arcuatus Wikipedia:Connecting_tubule - + @@ -49561,7 +49815,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Mesenchyme that is part of a developing trunk. EFO:0003485 EHDAA2:0002092 @@ -49577,14 +49831,14 @@ For example, A and B may be gene products and binding of B by A positively regul trunk mesenchyme - + - + EHDAA2 @@ -49675,6 +49929,12 @@ For example, A and B may be gene products and binding of B by A positively regul developing anatomical structure + + + + FBbt:00007006 + + @@ -49695,7 +49955,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Multi-tissue structure that arises from the heart rudiment and will become the heart tube. BTO:0006179 EHDAA2:0001512 @@ -49714,14 +49974,14 @@ For example, A and B may be gene products and binding of B by A positively regul primitive heart tube - + - + ZFA @@ -49734,7 +49994,9 @@ For example, A and B may be gene products and binding of B by A positively regul BTO:0006179 - https://orcid.org/0000-0003-4423-4370 + + + https://github.com/biopragmatics/biomappings @@ -49755,7 +50017,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -49784,7 +50046,7 @@ For example, A and B may be gene products and binding of B by A positively regul gonad primordium - + @@ -49797,7 +50059,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + ZFA @@ -49864,14 +50126,14 @@ For example, A and B may be gene products and binding of B by A positively regul - + - + A mesoderm that has the potential to develop into a pronephros. Portion of tissue that consists of the mesenchymal precursor to the pronephric kidney and that begins to separate from the intermediate mesoderm at NF stage 21 and epithelializes by NF stage 30.[AAO] AAO:0011090 @@ -49890,24 +50152,24 @@ For example, A and B may be gene products and binding of B by A positively regul the intermediate mesoderm of the chick embryo acquires its ability to form kidneys through its interactions with the paraxial mesoderm [ISBN:9780878932504 "Developmental Biology", PMID:10720431 "Signals from trunk paraxial mesoderm induce pronephros formation in chick intermediate mesoderm"]. These interactions induce the expression of TFs including Lim1, Pax2 and Pax6 that cause the intermediate mesoderm to form the kidney pronephric mesoderm - + - + - + ZFA - + Bgee:AN @@ -49963,7 +50225,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -49982,14 +50244,14 @@ For example, A and B may be gene products and binding of B by A positively regul glomerular tuft - + - + Wikipedia @@ -50220,7 +50482,7 @@ For example, A and B may be gene products and binding of B by A positively regul membrana basalis Wikipedia:Basement_membrane - + @@ -50246,7 +50508,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -50276,14 +50538,14 @@ For example, A and B may be gene products and binding of B by A positively regul glomerular basement membrane http://upload.wikimedia.org/wikipedia/commons/d/de/PhysiologieGlom%C3%A9rulaire.png - + - + true https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -50309,6 +50571,14 @@ For example, A and B may be gene products and binding of B by A positively regul GBM + + + + MESH:D050533 + + + https://github.com/biopragmatics/biomappings + @@ -50377,7 +50647,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + A delimited region of dense mesenchyme within looser mesenchyme. AEO:0000148 EHDAA2_RETIRED:0003148 @@ -50387,7 +50657,7 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0005856 developing mesenchymal condensation - + @@ -50406,7 +50676,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + AEO-modified-relation @@ -50499,7 +50769,7 @@ For example, A and B may be gene products and binding of B by A positively regul skeleton axiale Wikipedia:Axial_skeleton - + @@ -50514,7 +50784,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -50555,14 +50825,14 @@ For example, A and B may be gene products and binding of B by A positively regul cloacal membrane http://upload.wikimedia.org/wikipedia/commons/d/d2/Gray991.png - + - + Wikipedia @@ -50603,7 +50873,7 @@ For example, A and B may be gene products and binding of B by A positively regul membrana cloacalis Wikipedia:Cloacal_membrane - + @@ -50615,7 +50885,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + The notochordal plate is the dorsal part of the notochordal process when the ventral portion breaks down. It is continuous laterally with the endoderm that composes the roof of the primitive foregut and is in contact dorsally with the neural tube. The folding off of the notochordal plate gives rise to the notochord. TODO - check ordering; awaiting confirmation from JB The notochordal plate is the dorsal part of the notochordal process when the ventral portion breaks down. It is continuous laterally with the endoderm that composes the roof of the primitive foregut and is in contact dorsally with the neural tube. The folding off of the notochordal plate gives rise to the notochord. [Carson_JL, Dehart_DB, Developmental_Dynamics_(1994)_201:_260-278, Gesteland_K_and_Schoenwolf_GC, Inagaki_T, Morphogenesis_of_the_murine_node_and_notochordal_plate, The_prechordal_plate, Vrablic_T, see_Mueller_F_and_O'Rahilly_R, the_rostral_end_of_the_notochord_and_nearby_median_features_in_staged_human_embryos._Cells_Tissues_Organs_(2003)_173:_1-20_and_Sulik_K][VHOG] @@ -50630,7 +50900,7 @@ For example, A and B may be gene products and binding of B by A positively regul notochordal plate - + @@ -50643,7 +50913,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + EHDAA2 @@ -50680,7 +50950,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + A midline cellular cord formed from the migration of mesenchymal cells from the primitive knot. EHDAA2:0001279 EHDAA:224 @@ -50697,14 +50967,14 @@ For example, A and B may be gene products and binding of B by A positively regul The notochordal process grows cranially until it reaches the prechordal plate, the future site of the mouth. In this area the ectoderm is attached directly to the endoderm without intervening mesoderm. This area is known as the oropharyngeal membrane, and it will break down to become the mouth. At the other end of the primitive streak the ectoderm is also fused directly to the endoderm; this is known as the cloacal membrane (proctodeum), or primordial anus. notochordal process - + - + EHDAA2 @@ -51255,7 +51525,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + A region of nephron tubule that is part of a cortex of kidney. EMAPA:18976 MA:0002609 @@ -51265,14 +51535,14 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0006853 renal cortex tubule - + - + MA @@ -51329,6 +51599,12 @@ For example, A and B may be gene products and binding of B by A positively regul The distalmost portion of the digestive tract, derived from the hindgut, and terminating with the anus. http://orcid.org/0000-0002-6601-2165 + + + + FBbt:00005756 + + @@ -51757,7 +52033,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + A hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood or analogs[GO,modified]. note we reserve the subclass 'heart' from the vertebrate multi-chambered heart. 'The first heart-like organ is believed to have appeared 500my ago in an ancestral bilaterian'. Amniotes: four-chambered heart. Amphibians: two atria, one ventricle, pulmonary; fish: single atrium and ventricle; amphioxus: tubular, non-striated, closed, unidirectional; ascidians: tubular, striated, open, bidirectional; arthropods: tubular, open; C elegans: contractile pharynx; Cnideria: striated muscle cells associated with gastrodermis SPD:0000130 @@ -51772,14 +52048,14 @@ For example, A and B may be gene products and binding of B by A positively regul Gene notes: Bmp, Nkx, Gata primary circulatory organ - + - + GO uses blood circulation generically to include the haemolymphatic fluid of arthropods @@ -51869,7 +52145,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -51886,14 +52162,14 @@ For example, A and B may be gene products and binding of B by A positively regul presumptive segmental plate - + - + https://github.com/obophenotype/uberon/wiki/The-neural-crest EDHAA2 @@ -51992,7 +52268,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -52018,7 +52294,7 @@ For example, A and B may be gene products and binding of B by A positively regul presumptive paraxial mesoderm - + @@ -52034,7 +52310,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + https://github.com/obophenotype/uberon/issues/1277 @@ -52195,7 +52471,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Mesenchyme with little extracellular matrix. AEO:0000146 EHDAA2:0003146 @@ -52203,7 +52479,7 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0007524 dense mesenchyme tissue - + @@ -52216,7 +52492,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + AEO @@ -52424,6 +52700,12 @@ For example, A and B may be gene products and binding of B by A positively regul FBbt:00005426 http://flybase.org/reports/FBrf0178740.html + + + + FBbt:00005426 + + @@ -52431,7 +52713,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Anatomical system that consists of all blood and lymph vessels. consider merging with vasculature @@ -52450,14 +52732,14 @@ For example, A and B may be gene products and binding of B by A positively regul vascular system - + - + MA @@ -52617,7 +52899,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -52660,14 +52942,14 @@ For example, A and B may be gene products and binding of B by A positively regul pelvic girdle skeleton http://upload.wikimedia.org/wikipedia/commons/f/fe/Gray242.png - + - + PMID:21455939 @@ -52763,7 +53045,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + The functional tissue of the kidney, consisting of the nephrons. BTO:0003604 FMA:15574 @@ -52774,7 +53056,7 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0008987 renal parenchyma - + @@ -52787,7 +53069,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + FMA @@ -52857,7 +53139,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -52874,14 +53156,14 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0009142 entire embryonic mesenchyme - + - + EHDAA2 @@ -53000,7 +53282,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + EHDAA2:0002094 trunk and cervical paraxial mesenchyme uberon @@ -53008,14 +53290,14 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0009618 trunk paraxial mesoderm - + - + EHDAA2 @@ -53114,7 +53396,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + EFO:0003704 TAO:0005041 ZFA:0005041 @@ -53124,14 +53406,14 @@ For example, A and B may be gene products and binding of B by A positively regul anterior lateral plate mesoderm - + - + ZFA @@ -53228,7 +53510,7 @@ For example, A and B may be gene products and binding of B by A positively regul arteriae interlobares renis Wikipedia:Interlobar_arteries - + @@ -53277,7 +53559,7 @@ For example, A and B may be gene products and binding of B by A positively regul lobus FMA:45728 FMA:TA - + @@ -53369,7 +53651,7 @@ For example, A and B may be gene products and binding of B by A positively regul lobi renales Wikipedia:Renal_lobe - + @@ -53420,6 +53702,12 @@ For example, A and B may be gene products and binding of B by A positively regul An anatomical structure that has more than one cell as a part. CARO:0010000 + + + + FBbt:00100313 + + @@ -53460,7 +53748,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -53478,14 +53766,14 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0010227 future cardiac atrium - + - + ZFA @@ -53628,7 +53916,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -53642,7 +53930,7 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0010377 mesenchyme from somatopleure - + @@ -53655,7 +53943,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + EHDAA2 @@ -53671,7 +53959,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + A vessel of the microcirculature, lying between the arterioles and venules; includes capillaries (blood and lymphatic), metarterioles and arteriovenous anastomoses. MESH:D055806 TAO:0005251 @@ -53681,14 +53969,14 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0010523 microcirculatory vessel - + - + ZFA @@ -53721,7 +54009,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -53738,7 +54026,7 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0010532 primitive nephron - + @@ -53751,7 +54039,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + EHDAA2 @@ -53773,7 +54061,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -53784,7 +54072,7 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0010536 nephron progenitor - + @@ -53797,7 +54085,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + cjm @@ -54119,8 +54407,8 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + Anatomical cluster consisting of the skeletal elements (i.e. bone elements, cartilage elements, cartilage condensations) that are part of an individual subdivision of the organism. Excludes joints. Anatomical cluster consisting of the skeletal elements that are part of the skeleton.[VSAO] FMA:23879 @@ -54133,11 +54421,11 @@ For example, A and B may be gene products and binding of B by A positively regul subdivision of skeleton - + - + @@ -54150,13 +54438,13 @@ For example, A and B may be gene products and binding of B by A positively regul - + UBERONREF:0000003 - + VSAO @@ -54227,7 +54515,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Subdivision of the skeletal system which consists of the postcranial axial skeleton plus associated joints. axial skeletal system FMA:302077 @@ -54237,7 +54525,7 @@ For example, A and B may be gene products and binding of B by A positively regul postcranial axial skeletal system http://purl.obolibrary.org/obo/uberon/docs/The-axial-skeleton - + @@ -54250,7 +54538,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + cjm @@ -54274,7 +54562,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -54287,7 +54575,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Subdivision of urinary system which consists of the kidney and the ureters. FMA:45658 @@ -54300,24 +54588,24 @@ For example, A and B may be gene products and binding of B by A positively regul upper urinary tract - + - + - + FMA - + FMA-abduced-lr @@ -54343,12 +54631,14 @@ For example, A and B may be gene products and binding of B by A positively regul + FBbt:00007330 FMA:67509 SCTID:91690000 uberon UBERON:0011216 + organ system subdivision @@ -54364,6 +54654,12 @@ For example, A and B may be gene products and binding of B by A positively regul A subdivision of an anatomical system. http://orcid.org/0000-0002-6601-2165 + + + + FBbt:00007330 + + @@ -54639,7 +54935,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -54654,14 +54950,14 @@ For example, A and B may be gene products and binding of B by A positively regul We presume this is distinct from AAO:0001003, an external integumentary structure - check with amphibian anatomy ontology developers. AO notes: the text def states mesenchymal swelling, EHDAA2 splits into mesenchymal and epithelial parts embryonic cloacal fold - + - + EHDAA2 @@ -54684,20 +54980,20 @@ For example, A and B may be gene products and binding of B by A positively regul - + EHDAA2:0004588 uberon UBERON:0012361 internal anal region - + - + EHDAA2 @@ -54707,20 +55003,20 @@ For example, A and B may be gene products and binding of B by A positively regul - + EHDAA2:0004589 uberon UBERON:0012469 external anal region - + - + EHDAA2 @@ -54747,7 +55043,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -54767,14 +55063,14 @@ For example, A and B may be gene products and binding of B by A positively regul skeleton of pelvic complex - + - + FMA @@ -54826,7 +55122,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + The precursor of the urethra. In humans, the urethral groove is a temporary linear indentation on the underside (ventral side) of the male penis during embryonic development. It typically appears around 8 weeks of gestation and becomes closed into a normal male urethra by the 12th week SCTID:361531004 @@ -54838,14 +55134,14 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0013241 embryonic urethral groove - + - + Wikipedia @@ -54865,7 +55161,7 @@ For example, A and B may be gene products and binding of B by A positively regul sulcus urethralis primarius Wikipedia:Urethral_groove - + @@ -54985,7 +55281,6 @@ For example, A and B may be gene products and binding of B by A positively regul The region of the organism associated with the visceral organs. - Cardinal body part, which consists of a maximal set of diverse subclasses of organ and organ part spatially associated with the vertebral column and ribcage. Examples: There is only one body proper[FMA:231424]. AEO:0000103 BTO:0001489 @@ -54995,7 +55290,6 @@ For example, A and B may be gene products and binding of B by A positively regul body whole body UBERON:0013702 - body proper @@ -55073,7 +55367,9 @@ For example, A and B may be gene products and binding of B by A positively regul BTO:0006187 - https://orcid.org/0000-0003-4423-4370 + + + https://github.com/biopragmatics/biomappings @@ -55458,7 +55754,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -55481,7 +55777,7 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0016887 entire extraembryonic component - + @@ -55494,7 +55790,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + AEO @@ -55640,6 +55936,12 @@ For example, A and B may be gene products and binding of B by A positively regul Material anatomical entity consisting of multiple anatomical structures that are not connected to each other. CARO:0020000 + + + + FBbt:00007276 + + @@ -55915,23 +56217,25 @@ For example, A and B may be gene products and binding of B by A positively regul - + The upper tract of the renal system. The renal pelvis is the large cavity in the middle of each kidney. Urine drains from each kidney through a long tube called the ureter, into the bladder, where it is stored until it is passed from the body through the urethra. + NCIT:C54419 renal pelvis and ureter renal pelvis plus ureter uberon UBERON:0036295 + renal pelvis/ureter - + - + NCIT @@ -56009,7 +56313,9 @@ For example, A and B may be gene products and binding of B by A positively regul BTO:0006338 - https://orcid.org/0000-0003-4423-4370 + + + https://github.com/biopragmatics/biomappings @@ -56268,6 +56574,24 @@ For example, A and B may be gene products and binding of B by A positively regul /////////////////////////////////////////////////////////////////////////////////////// --> + + + + + + + + + + + + + + + + + + @@ -56298,6 +56622,16 @@ For example, A and B may be gene products and binding of B by A positively regul + + + + + + + + + + diff --git a/src/ontology/subsets/kidney_upper_slim.tsv b/src/ontology/subsets/kidney_upper_slim.tsv index 0fcb14222..134b85af5 100644 --- 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+_:Be350484aX2D0263X2D4acdX2Da142X2D4091eb1e8e26genid921 +_:Be350484aX2D0263X2D4acdX2Da142X2D4091eb1e8e26genid927 +_:Be350484aX2D0263X2D4acdX2Da142X2D4091eb1e8e26genid934 +_:Be350484aX2D0263X2D4acdX2Da142X2D4091eb1e8e26genid941 +_:Be350484aX2D0263X2D4acdX2Da142X2D4091eb1e8e26genid947 +_:Be350484aX2D0263X2D4acdX2Da142X2D4091eb1e8e26genid953 +_:Be350484aX2D0263X2D4acdX2Da142X2D4091eb1e8e26genid960 +_:Be350484aX2D0263X2D4acdX2Da142X2D4091eb1e8e26genid967 +_:Be350484aX2D0263X2D4acdX2Da142X2D4091eb1e8e26genid973 +_:Be350484aX2D0263X2D4acdX2Da142X2D4091eb1e8e26genid980 +_:Be350484aX2D0263X2D4acdX2Da142X2D4091eb1e8e26genid986 +_:Be350484aX2D0263X2D4acdX2Da142X2D4091eb1e8e26genid993 "continuant" "occurrent" "independent continuant" @@ -481,7 +478,6 @@ _:B6571aa82X2D487eX2D4480X2Db6d1X2D930b425859f2genid996 "acidophilic cytoplasm" "basophilic cytoplasm" "polychromatophilic cytoplasm" - "increased nucleus size" "epithelial cell of nephron" "epithelial cell of glomerular capsule" "kidney collecting duct epithelial cell" @@ -856,14 +852,9 @@ _:B6571aa82X2D487eX2D4480X2Db6d1X2D930b425859f2genid996 "quality" "morphology" "shape" - "qualitative" - "deviation (from_normal)" - "size" "structure" "branched" "circular" - "normal" - "increased size" "elliptic" "physical quality" "physical object quality" @@ -898,8 +889,6 @@ _:B6571aa82X2D487eX2D4480X2Db6d1X2D930b425859f2genid996 "subcylindrical" "3-D shape" "tubular" - "increased quality" - "increased object quality" "fiber shaped" "superelliptic" "acidophilic" @@ -908,6 +897,7 @@ _:B6571aa82X2D487eX2D4480X2Db6d1X2D930b425859f2genid996 "disconnected" "polymeric" "distensibility" + "high nuclear/cytoplasmic ratio" "anatomical structure quality" "anatomical histological quality" "polychromatophilic" diff --git a/subsets/blood_and_immune_upper_slim.json b/subsets/blood_and_immune_upper_slim.json index a642004a5..f2b3e3a5d 100644 --- a/subsets/blood_and_immune_upper_slim.json +++ b/subsets/blood_and_immune_upper_slim.json @@ -4,9 +4,9 @@ "meta" : { "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2002/07/owl#versionInfo", - "val" : "2024-01-04" + "val" : "2024-02-13" } ], - "version" : "http://purl.obolibrary.org/obo/cl/releases/2024-01-04/subsets/blood_and_immune_upper_slim.owl" + "version" : "http://purl.obolibrary.org/obo/cl/releases/2024-02-13/subsets/blood_and_immune_upper_slim.owl" }, "nodes" : [ { "id" : "http://purl.obolibrary.org/obo/BFO_0000002", @@ -731,7 +731,7 @@ "xrefs" : [ "CARO:mah" ] }, "comments" : [ "The definition of cell is intended to represent all cells, and thus a cell is defined as a material entity and not an anatomical structure, which implies that it is part of an organism (or the entirety of one)." ], - "subsets" : [ "http://purl.obolibrary.org/obo/ubprop#_upper_level" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/ubprop#_upper_level" ], "xrefs" : [ { "val" : "CALOHA:TS-2035" }, { @@ -772,7 +772,7 @@ "xrefs" : [ "GOC:tfm", "MESH:D013234" ] }, "comments" : [ "This term applies to metazoan. For plant stem cells, consider using PO:0004011 ‘initial cell’ or its parent PO:0004010 ‘meristematic cell’." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "animal stem cell" @@ -797,7 +797,7 @@ "xrefs" : [ "GOC:add", "GOC:dsd", "GOC:tfm", "PMID:19022770", "http://en.wikipedia.org/wiki/Hematopoietic_stem_cell" ] }, "comments" : [ "Markers differ between species, and two sets of markers have been described for mice. HSCs are reportedly CD34-positive, CD45-positive, CD48-negative, CD150-positive, CD133-positive, and CD244-negative." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "blood forming stem cell" @@ -837,7 +837,7 @@ "val" : "A progenitor cell committed to the erythroid lineage.", "xrefs" : [ "GOC:add", "ISBN:0721601464" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003000", "pred" : "hasRelatedSynonym", @@ -929,7 +929,7 @@ "xrefs" : [ "GOC:add", "ISBN:0878932437", "MESH:D023461" ] }, "comments" : [ "This cell type is intended to be compatible with any vertebrate common myeloid progenitor. For mammalian CMP known to be CD34-positive, please use the term 'common myeloid progenitor, CD34-positive' (CL_0001059)." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "common myeloid precursor" @@ -983,7 +983,7 @@ "xrefs" : [ "GOC:add", "GOC:dsd", "GOC:tfm", "MESH:D055015", "PMID:16647566", "http://en.wikipedia.org/wiki/Megakaryocyte-erythroid_progenitor_cell" ] }, "comments" : [ "MEPs are reportedly CD19-negative, CD34-negative, CD45RA-negative, CD110-positive, CD117-positive, and SCA1-negative and reportedly express the transcription factors GATA-1 and NF-E2." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "CFU-EM" @@ -1021,7 +1021,7 @@ "xrefs" : [ "GOC:add", "GOC:dsd", "GOC:tfm", "PMID:10407577", "PMID:16551251" ] }, "comments" : [ "CLP are CD7-positive, CD10-positive, CD19-negative, CD34-positive, CD45RA-positive, CD79a-negative, CD127-positive, AA4.1-positive, RAG-negative, Sca-1-low, sIgM-negative, sIgD-negative, TdT-negative, Vpre-B-negative, and pre-BCR-negative. Expression of transcription factors include E2A-positive, EBF-positive, Ikaros-negative, PU.1-negative, and Pax5-negative." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "common lymphocyte precursor" @@ -1086,6 +1086,7 @@ "xrefs" : [ "SANBI:mhl" ] }, "comments" : [ "define using PATO mulit-potent or oligopotent?" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "blast cell" @@ -1127,7 +1128,7 @@ "xrefs" : [ "ISBN:0517223651", "MESH:D005347", "http://en.wikipedia.org/wiki/Fibroblast" ] }, "comments" : [ "These cells may be vimentin-positive, fibronectin-positive, fsp1-positive, MMP-1-positive, collagen I-positive, collagen III-positive, and alpha-SMA-negative." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { "val" : "BTO:0000452" }, { @@ -1153,7 +1154,7 @@ "val" : "A cell that is usually found in a two-dimensional sheet with a free surface. The cell has a cytoskeleton that allows for tight cell to cell contact and for cell polarity where apical part is directed towards the lumen and the basal part to the basal lamina.", "xrefs" : [ "FB:ma", "GOC:tfm", "MESH:D004847" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "epitheliocyte" @@ -1188,7 +1189,7 @@ "val" : "An endothelial cell that lines the vasculature.", "xrefs" : [ "GOC:tfm" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cuboidal endothelial cell of vascular tree" @@ -1203,6 +1204,7 @@ "lbl" : "squamous epithelial cell", "type" : "CLASS", "meta" : { + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "CALOHA:TS-1249" } ] @@ -1226,7 +1228,7 @@ "val" : "A cell found predominately in the blood.", "xrefs" : [ "GOC:add", "GOC:tfm" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim" ], "xrefs" : [ { "val" : "FMA:62844" }, { @@ -1242,7 +1244,7 @@ "val" : "A type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex.", "xrefs" : [ "GOC:add", "GOC:tfm", "ISBN:0781735149" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "T lymphocyte" @@ -1285,6 +1287,7 @@ "xrefs" : [ "GOC:add", "GOC:tfm", "GO_REF:0000031", "ISBN:0781735149", "PMID:10428500", "PMID:15055519", "PMID:17380158" ] }, "comments" : [ "Morphology: Highly vesicular; markers: Surface: RANK, cFMS (MCSF receptor); Secreted: cathepsin K and TRAP (tartate resistant acid phosphatase); transcription factors: PU.1, cFOS, MITF, NFkB (p52); role or process: tissue remodelling: bone resorption; lineage: hematopoietic, myeloid." ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "chondroclast" @@ -1308,7 +1311,7 @@ "val" : "A leukocyte with abundant granules in the cytoplasm.", "xrefs" : [ "GOC:amm", "GOC:tfm", "MESH:D006098", "http://en.wikipedia.org/wiki/Granulocyte" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "granular leucocyte" @@ -1343,7 +1346,7 @@ "xrefs" : [ "GOC:add", "GOC:dsd", "GOC:tfm", "ISBN:068340007X", "MESH:D008407", "PMCID:PMC1312421", "PMCID:PMC2855166", "PMID:15153310", "PMID:16455980", "PMID:19671378", "PMID:212366338", "PMID:9354811" ] }, "comments" : [ "Mast cells are generally integrin beta-7-negative and positive for TLR2, TLR3, TLR4, TLR5, TLR7, TLR9, C3aR, C5aR, CR3, CR4, VEGF, FGF2, and renin. They can express MHC Class I and II on their surface. Activated murine mast cells (IgE+Antigen) were capable of expressing the following co-stimulatory molecules: CD95 (Fas), CD120b, CD137 (4-1BB), CD153 (CD30L), CD154 (CD40L), GITR, ICOSL, OX40L, PD-L1, and PD-L2. Note that there was some mouse strain variation. Mast cells have also been demonstrated to produce bFGF, CCL2, CCL4, CCL5, CCL11, CCL20, CXCL2, CXCL8, CXCL10, GM-CSF, IFN-gamma, IL-1, IL-2, IL-3, IL-8, IL-10, IL-11, IL-12, IL-13, IL-16, IL-25, IL-18, MIP-1, prostaglandin D2, SCF, TGF-beta, TNF-alpha, TSLP, VEGF, and XCL1. They express the transcription factors Transcription factors AP-1, GATA1, MITF, Notch2, PIAS3, PU.1, and STAT5." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "histaminocyte" @@ -1381,7 +1384,7 @@ "val" : "A vertebrate phagocyte with a single nucleus.", "xrefs" : [ "GOC:add", "GOC:tfm", "ISBN:0781735149" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { "val" : "BTO:0001433" } ], @@ -1400,7 +1403,7 @@ "xrefs" : [ "GOC:tfm", "MESH:D042783", "PMID:21275341", "http://en.wikipedia.org/wiki/Endothelial_cell", "https://sourceforge.net/tracker/?func=detail&atid=440764&aid=3364936&group_id=36855" ] }, "comments" : [ "From FMA: 9.07.2001: Endothelial cell has always been classified as a kind of epithelial cell, specifically a squamous cell but that is not true. First, endothelial cell can either be squamous or cuboidal (e.g. high-endothelial cell) and secondly, it has different embryological derivation (mesodermal) than a true epithelial cell (ectodermal and endodermal). The basis for present classification is the fact that it comprises the outermost layer or lining of anatomical structures (location-based) but a better structural basis for the differentia is the cytoskeleton of the cell. Endothelial cell has vimentin filaments while an epithelial cell has keratin filaments. [Onard]." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "endotheliocyte" @@ -1441,6 +1444,7 @@ "xrefs" : [ "FB:ma", "GOC:dsd", "PMCID:PMC2613570", "PMID:10102814", "PMID:16923606", "PMID:17986482", "PMID:19960544", "http://en.wikipedia.org/wiki/Mesenchymal_stem_cell", "http://www.copewithcytokines.de/cope.cgi?key=mesenchymal%20stem%20cells" ] }, "comments" : [ "Many but not all mesenchymal cells derive from the mesoderm. MSCs are reportedly CD3-negative, CD4-negative, CD5-negative, CD8-negative, CD11a-negative, CD11b-negative, CD14-negative, CD19-negative, CD29-positive, CD31-negative, CD34-negative, CD38-negative, CD40-negative, CD44-positive, CD45-negative, CD49-positive, CD54-positive, CD66b-negative, CD79a-negative, CD80-negative, CD102-positive, CD106-positive, CD117-positive, CD121a-positive, CD121b-positive, CD123-positive, CD124-positive, CD133-negative, CD146-positive, CD166-positive, CD271-positive, B220-negative, Gr1-negative, MHCI-positive, MHCII-negative, SSEA4-negative, sca1-positive, Ter119-negative, and glycophorin A-negative. Cultured MSCs are capable of producing stem cell factor, IL7, IL8, IL11, TGF-beta, cofilin, galectin-1, laminin-receptor 1, cyclophilin A, and MMP-2." ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "bone marrow stromal cells" @@ -1510,7 +1514,7 @@ "xrefs" : [ "GOC:add", "ISBN:0781735149" ] }, "comments" : [ "Note change of name; nearly all somatic cells can present antigens to T cells via MHC Class I complexes leading to effector responses, but professional antigen presenting cells constitutively express MHC Class II as well as costimulatory molecules, and thus can initiate immune responses via T cells." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003000", "pred" : "hasRelatedSynonym", @@ -1526,6 +1530,7 @@ "val" : "A cell that specializes in controlled release of one or more substances.", "xrefs" : [ "GOC:tfm", "ISBN:0721662544" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "BTO:0003659" }, { @@ -1540,7 +1545,8 @@ "definition" : { "val" : "A cell whose primary function is to shorten.", "xrefs" : [ "FB:ma" ] - } + }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000187", @@ -1551,6 +1557,7 @@ "val" : "A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns.", "xrefs" : [ "MESH:D032342" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "muscle fiber" @@ -1646,6 +1653,7 @@ "val" : "A cell of the middle germ layer of the embryo.", "xrefs" : [ "MESH:D008648" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "mesoblast" @@ -1735,7 +1743,7 @@ "val" : "A red blood cell. In mammals, mature erythrocytes are biconcave disks containing hemoglobin whose function is to transport oxygen.", "xrefs" : [ "GOC:tfm", "MESH:D004912" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "RBC" @@ -1765,7 +1773,7 @@ "xrefs" : [ "GOC:add", "GOC:dsd", "GOC:tfm", "MESH:D001792", "PMID:11110672", "PMID:16987572", "PMID:17204662", "PMID:17479180", "PMID:20414831", "http://en.wikipedia.org/wiki/Platelet" ] }, "comments" : [ "Platelets are reportedly CCR1-positive, CCR2-negative, CCR3-positive, CCR4-positive, CCR5-negative, CCR6-negative, CCR7-negative, CCR8-negative, CCR9-negative, CCR10-negative, CD16-positive, CD23-positive, CD32-positive, CD40-positive, CD41-positive CD42-positive, CD61-positive, CD62P-positive, CD64-positive, CD89-positive, CD102-positive, CD147-positive (activated platelets), CD154-positive (activated platelets), CD162-positive, CD209, CD282-positive, CD284-positive, CD289-positive, CD181-negative, CD182-negative, CD183-negative, CD184-positive, CLEC2-positive, GPVI-positive, JAMC-positive, PAR1-positive, PAR2-negative, PAR3-positive, PAR4-positive, TSP1-positive, and TXA2R-positive. Platelets can reportedly produce CCL2, CCL3, CCL5, CCL7, CCL17, CD40L, CXCL1, CXCL4, CXCL4L1, CXCL5, CXCL7, CXCL8, CXCL12, EGF, factor V, factor VII, factor XI, factor XIII, bFGF, histamine, IGF-1, IL-1beta, PAI-1, PDGF, plasminogen, protein S, serotonin, TGF-beta, TFPI, VEGF, and vWF." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "anucleate thrombocyte" @@ -1797,6 +1805,7 @@ "val" : "Any cell capable of ingesting particulate matter via phagocytosis.", "xrefs" : [ "GOC:add", "ISBN:0721601464" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "BTO:0001044" }, { @@ -1815,7 +1824,7 @@ "xrefs" : [ "GOC:add", "GOC:tfm", "GO_REF:0000031", "PMID:16213494", "PMID:1919437" ] }, "comments" : [ "Morphology: Diameter 30_M-80 _M, abundant cytoplasm, low N/C ratio, eccentric nucleus. Irregular shape with pseudopods, highly adhesive. Contain vacuoles and phagosomes, may contain azurophilic granules; markers: Mouse & Human: CD68, in most cases CD11b. Mouse: in most cases F4/80+; role or process: immune, antigen presentation, & tissue remodelling; lineage: hematopoietic, myeloid." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "histiocyte" @@ -1845,7 +1854,7 @@ "val" : "A lymphocyte of B lineage that is capable of B cell mediated immunity.", "xrefs" : [ "GOC:add", "GOC:tfm", "GO_REF:0000031", "ISBN:0781735149" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "B lymphocyte" @@ -1877,6 +1886,7 @@ "lbl" : "eukaryotic cell", "type" : "CLASS", "meta" : { + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "MESH:D005057" } ] @@ -1979,7 +1989,7 @@ "val" : "A cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation. These cells are lineage negative (CD3-negative, CD19-negative, CD34-negative, and CD56-negative).", "xrefs" : [ "GOC:add", "ISBN:0781735149" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "interdigitating cell" @@ -2052,7 +2062,7 @@ "xrefs" : [ "MESH:D009474", "http://en.wikipedia.org/wiki/Neuron" ] }, "comments" : [ "These cells are also reportedly CD4-negative and CD200-positive. They are also capable of producing CD40L and IFN-gamma." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "nerve cell" @@ -2088,7 +2098,7 @@ "xrefs" : [ "GOC:add", "ISBN:0683073696", "ISBN:0781735149" ] }, "comments" : [ "Editors note: consider adding taxon constraint to vertebrata (PMID:18025161)" ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { "val" : "BTO:0000775" }, { @@ -2114,7 +2124,7 @@ "val" : "An immature, nucleated erythrocyte occupying the stage of erythropoeisis that follows formation of erythroid progenitor cells. This cell is CD71-positive, has both a nucleus and a nucleolus, and lacks hematopoeitic lineage markers.", "xrefs" : [ "ISBN:0721601464", "PMID:1638021" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "rubriblast", @@ -2238,7 +2248,7 @@ "xrefs" : [ "GOC:dsd", "GOC:tfm", "ISBN:0721601464" ] }, "comments" : [ "Lineage negative is described here as CD2-negative, CD3-negative, CD4-negative, CD5-negative, CD8a-negative, CD14-negative, CD19-negative, CD20-negative, CD56-negative, Ly6g-negative, and Ter119-negative." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "CFU-Meg", @@ -2298,7 +2308,7 @@ "xrefs" : [ "ISBN:0721601464", "MESH:D008533", "PMID:31043076", "http://en.wikipedia.org/wiki/Megakaryocyte" ] }, "comments" : [ "Megakaryocytes are reportedly CD181-positive and CD182-positive." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "megacaryocyte" @@ -2331,7 +2341,7 @@ "xrefs" : [ "GOC:amm", "GOC:dsd", "GOC:tfm", "GO_REF:0000031", "ISBN:0721601464", "MESH:D055014", "PMCID:PMC2213186", "PMCID:PMC548021", "PMID:16551251", "PMID:16647566", "http://en.wikipedia.org/wiki/CFU-GM", "http://www.copewithcytokines.de" ] }, "comments" : [ "Originally described in the dendritic cell ontology (DC_CL:0000042)(PMID:19243617). GMPs are reportedly CD16-positive, CD32-positive, CD34-positive, CD38-positive, CD45RA-positive, CD110-negative, CD117-positive, CD123-positive, and SCA1-negative." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "CFU-C , Colony forming unit in culture", @@ -2375,7 +2385,7 @@ "val" : "An immature erythrocyte that changes the protein composition of its plasma membrane by exosome formation and extrusion. The types of protein removed differ between species though removal of the transferrin receptor is apparent in mammals and birds.", "xrefs" : [ "GOC:add", "GOC:tfm", "PMID:15946868", "PMID:2037622" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "BTO:0001173" }, { @@ -2394,7 +2404,7 @@ "xrefs" : [ "GOC:tfm", "ISBN:0721601464" ] }, "comments" : [ "Morphology: Mononuclear cell, diameter 14-18 _M, fine azurophilic granules; markers: CD11b (shared with many other myeloid cells); location: Adult: bone marrow; Fetal: Liver, Yolk Sac; role or process: hematopoiesis, monocyte development; lineage: hematopoietic, myeloid." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { "val" : "BTO:0004657" }, { @@ -2433,7 +2443,7 @@ "xrefs" : [ "GO_REF:0000031", "MESH:D009000" ] }, "comments" : [ "Morphology: Mononuclear cell, diameter, 14 to 20 _M, N/C ratio 2:1-1:1. Nucleus may appear in variety of shapes: round, kidney, lobulated, or convoluted. Fine azurophilic granules present; markers: CD11b (shared with other myeloid cells), human: CD14, mouse: F4/80-mid,GR1-low; location: Blood, but can be recruited into tissues; role or process: immune & tissue remodelling; lineage: hematopoietic, myeloid." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { "val" : "BTO:0000876" }, { @@ -2494,7 +2504,8 @@ "definition" : { "val" : "A non-terminally differentiated cell that is capable of developing into a muscle cell.", "xrefs" : [ "GOC:add" ] - } + }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000723", @@ -2520,7 +2531,7 @@ "val" : "An achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue.", "xrefs" : [ "GOC:add", "GOC:tfm", "ISBN:978-0-323-05290-0" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "leucocyte" @@ -2568,6 +2579,7 @@ "val" : "A cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage.", "xrefs" : [ "GOC:add" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "BTO:0001441" }, { @@ -2586,7 +2598,7 @@ "xrefs" : [ "GOC:add", "GOC:tfm" ] }, "comments" : [ "Note that in FMA erythropoietic cells are types of nucleated erythrocytes and thus don't include erythrocytes." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "erythropoietic cell" @@ -2612,7 +2624,7 @@ "val" : "A nucleated precursor of an erythrocyte that lacks hematopoietic lineage markers.", "xrefs" : [ "GOC:add", "ISBN:0721601464", "PMID:18174176" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "normoblast" @@ -2635,7 +2647,8 @@ "definition" : { "val" : "A cell of the monocyte, granulocyte, or mast cell lineage.", "xrefs" : [ "GOC:add" ] - } + }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000767", @@ -2647,7 +2660,7 @@ "xrefs" : [ "GOC:add", "GOC:amm", "GOC:dsd", "GOC:tfm", "ISBN:0721601464", "MESH:D001491", "PMCID:PMC2626675", "PMID:11927641", "PMID:19741522", "PMID:21236338", "PMID:9933081" ] }, "comments" : [ "Matures in the bone marrow and account for <1% of leukocytes in the peripheral blood, spleen, and bone marrow. Basophils are described as being CD11a-positive, CD11b-positive, CD13-positive, CD15-positive, CD18-positive, CD21-positive, CD25-positive, CD29-positive, CD35-positive, CD40-positive, CD40L-positive, CD44-positive, CD45R-negative, CD46-positive, CD49a-positive, CD49b-positive, CD49d-positive, CD55-positive, CD59-positive, CD62L-positive, CD63-positive, CD69-positive, CD90-negative, CD116-positive, CD117-negative, CD124-positive, CD125-positive, CD131-positive, CD161-positive, CD184-positive, CD191-positive, CD192-positive, CD197-positive, CD200R3-positive, CD218-positive, CD282-positive, CD284-positive, CD289-positive, CD290-positive, CD294-positive, natural killer cell receptor 2B4-positive, smad1-positive, CD3-negative, CD4-negative, CD7-negative, CD8-negative, CD14-negative, CD15-negative, CD16-negative, CD19-negative, CD20-negative, CD34-negative, CD36-negative, CD45R-negative, CD56-negative, CD57-negative, CD235a-negative, and GR1-negative. Transcription factors- GATA1-positive, PU.1-positive." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "polymorphonuclear leucocyte" @@ -2683,7 +2696,7 @@ "xrefs" : [ "GOC:add", "GOC:amm", "GOC:dsd", "GOC:tfm", "ISBN:0721601464", "PMCID:PMC2626675", "PMID:10914487", "PMID:1662676" ] }, "comments" : [ "Eosinophils are also CD14-negative, CD32-positive, CD44-positive, CD48-positive, CD69-positive, CD192-negative, MBP1-positive, MBP2-positive, TLR2-negative, TLR4-negative, and lineage-negative (B220, CD2, CD14, CD19, CD56, CD71, CD117, CD123, CD235a (glycophorin A), and TER119). The cytokines IL-3, IL-5, and GM-CSF are involved in their development and differentiation. Usually considered CD16-negative, CD16 is observed on eosinophilic metamyelocyte." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "polymorphonuclear leucocyte" @@ -2726,7 +2739,7 @@ "val" : "Any of the immature or mature forms of a granular leukocyte that in its mature form has a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes.", "xrefs" : [ "GOC:add", "GOC:amm", "GOC:tfm", "ISBN:0721601464" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "PMN" @@ -2788,6 +2801,7 @@ "xrefs" : [ "GOC:add", "PMID:10449155", "PMID:17332250", "PMID:9521319" ] }, "comments" : [ "These cells are CD1a-negative, CD1b-positive, CD11a-positive, CD11c-positive, CD13-positive, CD14-negative, CD20-negative, CD21-negative, CD33-positive, CD40-negative, CD50-positive, CD54-positive, CD58-positive, CD68-negative, CD80-negative, CD83-negative, CD85j-positive, CD86-positive, CD89-negative, CD95-positive, CD120a-negative, CD120b-positive, CD123-negative, CD178-negative, CD206-negative, CD207-negative, CD209-negative, and TNF-alpha-negative. Upon TLR stimulation, they are capable of producing high levels of TNF-alpha, IL-6, CXCL8 (IL-8)." ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "interdigitating cell" @@ -2814,7 +2828,7 @@ "val" : "A dendritic cell type of distinct morphology, localization, and surface marker expression (CD123-positive) from other dendritic cell types and associated with early stage immune responses, particularly the release of physiologically abundant amounts of type I interferons in response to infection.", "xrefs" : [ "GOC:add", "GOC:dsd", "PMCID:PMC2118448", "PMCID:PMC538703", "PMID:15549123", "PMID:17332250", "PMID:17850486", "PMID:20304825" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "DC2" @@ -2861,6 +2875,7 @@ "xrefs" : [ "GOC:add", "GOC:dsd", "ISBN:0781735149" ] }, "comments" : [ "Mature B cells are also reportedly CD10-negative, CD19-positive, CD22-positive, CD34-negative, CD48-positive, CD79a-positive, CD84-positive, CD127-negative, CD352-positive, RAG-negative, TdT-negative, Vpre-B-negative, and pre-BCR-negative. Transcription factors expressed: Pax5-positive." ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "mature B lymphocyte" @@ -2882,7 +2897,7 @@ "xrefs" : [ "GOC:add", "GOC:dsd", "GO_REF:0000031", "ISBN:0721601464", "ISBN:0781735149", "PMID:19447676", "PMID:20081059", "PMID:20839338", "PMID:20951740", "http://en.wikipedia.org/wiki/Plasma_cell" ] }, "comments" : [ "Plasma cells develop in the spleen and migrate to the bone marrow. Plasma cells are also reportedly CD5-negative, CD10-negative, CD19-positive, CD20-negative, CD21-negative, CD22-negative, CD23-negative, CD24-negative, CD25-negative, CD27-positive, CD34-negative, CD38-positive, CD40-positive, CD43-positive, CD45-positive, CD48-positive, CD53-low, CD80-negative, CD81-positive, CD86-positive, CD95-positive, CD196-negative, CD229-positive, CD270-positive, CD352-positive, CD361-positive, and IgD-negative. Transcription factors: BLIMP1-positive, IRF4-positive, PAX5-negative, SpiB-negative, Ets1-negative, and XBP1-positive." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "plasma B cell" @@ -2923,7 +2938,7 @@ "val" : "A T cell that expresses an alpha-beta T cell receptor complex.", "xrefs" : [ "GOC:add", "GOC:tfm", "ISBN:0781735149" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "alpha-beta T lymphocyte" @@ -2945,7 +2960,7 @@ "xrefs" : [ "GOC:add", "GOC:tfm", "ISBN:0781735149" ] }, "comments" : [ "Note that gamma-delta T cells have both thymic and extrathymic differentiation pathways." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "gamma-delta T lymphocyte" @@ -2978,7 +2993,7 @@ "xrefs" : [ "GOC:add", "GOC:dsd", "GOC:rhs", "GOC:tfm", "GO_REF:0000031", "ISBN:0781735149", "PMID:20081059", "PMID:20839338" ] }, "comments" : [ "Immature B cells are also reportedly CD5-positive, CD10-positive, CD19-positive, CD20-positive, CD21-positive, CD22-positive, CD24-positive, CD25-negative, CD27-negative, CD34-negative, CD38-positive, CD40-positive, CD43-negative, CD45-positive, CD48-positive, CD53-positive, CD79a-positive, CD80-negative, CD81-positive, CD86-negative, CD95-negative, CD127-negative, CD138-negative, CD185-positive, CD196-positive, MHCII/HLA-DR-positive, RAG-positive, TdT-negative, Vpre-B-negative, and preBCR-negative. Transcription factors expressed: Pax5-positive." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "immature B lymphocyte" @@ -3007,7 +3022,7 @@ "val" : "A precursor B cell is a B cell with the phenotype CD10-positive.", "xrefs" : [ "GOC:rhs", "GOC:tfm", "GO_REF:0000031" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "pre-B cell" @@ -3032,7 +3047,7 @@ "xrefs" : [ "GOC:add", "GO_REF:0000031", "ISBN:0781735149", "PMID:12810111", "PMID:22343568" ] }, "comments" : [ "This cell type is compatible with the HIPC Lyoplate markers for 'transitional B cell'." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "transitional B cell", @@ -3071,7 +3086,7 @@ "xrefs" : [ "GOC:add", "GOC:dsd", "ISBN:0781735149", "PMID:12633665", "PMID:16551251", "PMID:18432934" ] }, "comments" : [ "Human pro-B cells are reportedly CD10-positive, CD22-positive, CD34-positive, CD38-positive, CD45-low, CD48-positive, CD79a-positive, CD127-positive, CD184-positive, RAG-positive, TdT-positive, Vpre-B-positive, pre-BCR-negative, IgD-negative, and IgM-negative. Transcription factors expressed: Pax5-positive, EBF-positive, E2A-negative, Ikaros-negative, and PU.1-negative." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "pre-pro B cell", @@ -3119,6 +3134,7 @@ "val" : "A lymphoid progenitor cell of the T cell lineage, with some lineage specific marker expression, but not yet fully committed to the T cell lineage.", "xrefs" : [ "GOC:add", "ISBN:0781735149" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "pro-T lymphocyte" @@ -3181,7 +3197,7 @@ "xrefs" : [ "GOC:add", "GOC:tfm", "PMID:19022770" ] }, "comments" : [ "Markers differ between mouse and human." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "MPP" @@ -3209,6 +3225,7 @@ "xrefs" : [ "GOC:add", "GOC:tfm" ] }, "comments" : [ "Note that this is a class of cell types, not an identified single cell type." ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "lymphoid progenitor cell" @@ -3231,7 +3248,7 @@ "xrefs" : [ "GOC:add", "GOC:tfm", "PMID:19022770" ] }, "comments" : [ "Note that this is a class of cell types, not an identified single cell type." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "myeloid progenitor cell" @@ -3257,7 +3274,7 @@ "val" : "A leukocyte with a single non-segmented nucleus in the mature form.", "xrefs" : [ "GOC:add" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "mononuclear leukocyte" @@ -3321,6 +3338,7 @@ "xrefs" : [ "GOC:dsd", "GOC:rhs", "GOC:tfm", "GO_REF:0000031", "PMID:16551251", "PMID:18432934", "PMID:9785673" ] }, "comments" : [ "Small pre-B-II cells are also reportedly CD10-positive, CD19-positive, CD34-negative, CD79a-positive, CD127-negative, TdT-negative, Vpre-B-negative, sIgM-negative, and sIgD-negative. Transcription factors: PU.1-positive, Ikaros-positive, E2A-positive, and PAX5-positive." ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "small pre-BII cell" @@ -3359,7 +3377,7 @@ "xrefs" : [ "GOC:dsd", "GOC:msz", "GOC:tfm", "GO_REF:0000031", "PMCID:PMC2673126" ] }, "comments" : [ "This cell type is compatible with the HIPC Lyoplate markers for 'plasmablast'. Plasmablasts are also reportedly CD48-positive, CD63-positive, CD229-positive, CD270-positive, CD319-positive, CD352-positive, CD361-positive, and IgD-negative." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "CD20-negative B cell" @@ -3384,6 +3402,7 @@ "val" : "A cell of a hematopoietic lineage.", "xrefs" : [ "GOC:add", "GO_REF:0000031" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "haematopoietic cell" @@ -3414,7 +3433,7 @@ "xrefs" : [ "GOC:amm", "GO_REF:0000031", "PMID:17850486" ] }, "comments" : [ "Originally described in the dendritic cell ontology (DC_CL:0000003)(PMID:19243617) These cells are also CD20-negative, MHCII-positive." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "interdigitating cell" @@ -3496,7 +3515,7 @@ "val" : "A lymphocyte that lacks characteristic T cell, B cell, myeloid cell, and dendritic cell markers, that functions as part of the innate immune response to produce cytokines and other effector responses.", "xrefs" : [ "GOC:add", "GOC:dsd", "PMID:23292121", "PMID:23348417" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" @@ -3562,6 +3581,7 @@ "val" : "A progenitor cell that can give rise to plasmacytoid and myeloid dendritic cells, and to monocytes and macrophages.", "xrefs" : [ "GOC:tfm", "PMID:19273628" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "MDP" @@ -3584,6 +3604,7 @@ "xrefs" : [ "GOC:ak", "GOC:dsd", "GOC:tfm", "PMCID:PMC1312421" ] }, "comments" : [ "There may be an intermediate cell type. These cells also CD13-positive, CD16-positive, CD32-positive, and integrin beta 7-positive. Transcription factors: GATA1-positive, MCP-1-positive, mitf-positive, PU.1-positive, and CEBP/a-low." ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "BMCP" @@ -3712,6 +3733,7 @@ "xrefs" : [ "GOC:tfm", "ISBN:0618947256" ] }, "comments" : [ "MH consider whether bone marrow cells are bone cells in the structural sense vs. being part of bone organ sense." ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "BTO:0004850" }, { @@ -3737,6 +3759,7 @@ "xrefs" : [ "GOC:dsd", "GOC:tfm", "PMID:12768659" ] }, "comments" : [ "These cells are reportedly CD31-positive, CD34-positive, CD144-positive, TAL1-positive." ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "vascular endothelial cell" @@ -3768,6 +3791,7 @@ "val" : "A cell involved in the formation of a granulocyte.", "xrefs" : [ "GOC:tfm" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "FMA:83519" } ], @@ -3845,6 +3869,7 @@ "val" : "A cell that is part of the nervous system.", "xrefs" : [ "GOC:tfm", "ISBN:0618947256" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "CALOHA:TS-2040" }, { @@ -3867,6 +3892,7 @@ "val" : "A cell of the supporting or framework tissue of the body, arising chiefly from the embryonic mesoderm and including adipose tissue, cartilage, and bone.", "xrefs" : [ "GOC:tfm", "ISBN:0618947256" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "CALOHA:TS-2096" }, { @@ -3915,7 +3941,7 @@ "val" : "A T cell that has not completed T cell selection.", "xrefs" : [ "GOC:tfm" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "immature T-cell" @@ -4048,7 +4074,8 @@ "definition" : { "val" : "Any hematopoietic cell that is a precursor of some other hematopoietic cell type.", "xrefs" : [ "GOC:dos" ] - } + }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0008019", @@ -4058,7 +4085,7 @@ "definition" : { "val" : "A non-polarised cell precursor cell that is part of some mesenchyme, is associated with the cell matrix but is not connected to other cells and is capable of migration." }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "mesenchyme cell" @@ -4092,7 +4119,8 @@ "definition" : { "val" : "A cell of the neural crest. Neural crest cells are multipotent. Premigratory neural crest cells are found at the neural plate boarder, some of which will undergo ectomesynchymal transition and delamination to form migratory neural crest cells.", "xrefs" : [ "https://orcid.org/0000-0001-5208-3432", "https://orcid.org/0000-0002-9900-7880" ] - } + }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0011026", @@ -4103,6 +4131,7 @@ "val" : "A precursor cell that has a tendency to differentiate into a specific type of cell. They are descendants of stem cells, only they are more constrained in their differentiation potential or capacity for self-renewal, and are often more limited in both senses.", "xrefs" : [ "ISBN:978-1-62808-994-3", "https://doi.org/10.1016/B978-0-12-409503-8.00002-0" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0001-5208-3432" @@ -4117,7 +4146,8 @@ "val" : "A cell that, by division or terminal differentiation, can give rise to other cell types.", "xrefs" : [ "GOC:dos" ] }, - "comments" : [ "Work is needed on GO 'cell differentiation' before it is clear whether the equivalent class definition 'native cell' that capable_of some 'cell differentiation' works. Also, may want to consider merging this with non-terminally differentiated cell." ] + "comments" : [ "Work is needed on GO 'cell differentiation' before it is clear whether the equivalent class definition 'native cell' that capable_of some 'cell differentiation' works. Also, may want to consider merging this with non-terminally differentiated cell." ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0017005", @@ -4239,23 +4269,6 @@ "val" : "2009-12-28T04:25:23Z" } ] } - }, { - "id" : "http://purl.obolibrary.org/obo/CL_0017505", - "lbl" : "increased nucleus size", - "type" : "CLASS", - "meta" : { - "definition" : { - "val" : "A nucleus size quality which is relatively high compared to the amount of cytoplasm present in the same cell.", - "xrefs" : [ "GOC:tfm" ] - }, - "basicPropertyValues" : [ { - "pred" : "http://purl.org/dc/terms/contributor", - "val" : "https://orcid.org/0000-0003-1980-3228" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", - "val" : "2009-12-23T10:53:24Z" - } ] - } }, { "id" : "http://purl.obolibrary.org/obo/CL_0017508", "lbl" : "cartwheel heterochromatin", @@ -4304,6 +4317,7 @@ "val" : "A leukocyte with a single non-segmented nucleus in the mature form found in the circulatory pool of blood.", "xrefs" : [ "GOC:TermGenie" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://www.wikidata.org/entity/Q35563349" @@ -6349,7 +6363,7 @@ "type" : "CLASS", "meta" : { "definition" : { - "val" : "A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex).", + "val" : "A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex).", "xrefs" : [ "GOC:pdt" ] }, "comments" : [ "Note that, in addition to forming the root of the cellular component ontology, this term is recommended for the annotation of gene products whose cellular component is unknown. When this term is used for annotation, it indicates that no information was available about the cellular component of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this." ], @@ -6389,7 +6403,7 @@ "xrefs" : [ "GOC:go_curators" ] }, "comments" : [ "Note that this term is intended to annotate gene products that are not attached to the cell surface. For gene products from multicellular organisms which are secreted from a cell but retained within the organism (i.e. released into the interstitial fluid or blood), consider the cellular component term 'extracellular space ; GO:0005615'." ], - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_yeast", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "extracellular" @@ -6507,7 +6521,7 @@ "xrefs" : [ "ISBN:0198547684" ] }, "comments" : [ "Note that for multicellular organisms, the extracellular space refers to everything outside a cell, but still within the organism (excluding the extracellular matrix). Gene products from a multi-cellular organism that are secreted from a cell into the interstitial fluid or blood can therefore be annotated to this term." ], - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "intercellular space" @@ -6597,7 +6611,7 @@ "xrefs" : [ "ISBN:0198547684" ] }, "comments" : [ "Chromosomes include parts that are not part of the chromatin. Examples include the kinetochore." ], - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_yeast", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "interphase chromosome" @@ -6645,7 +6659,7 @@ "val" : "The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.", "xrefs" : [ "ISBN:0198547684" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_yeast", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "xrefs" : [ { "val" : "Wikipedia:Cytoplasm" } ], @@ -6759,7 +6773,7 @@ "val" : "An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins.", "xrefs" : [ "ISBN:0198506732" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_yeast", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "free ribosome", @@ -6794,7 +6808,7 @@ "val" : "The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.", "xrefs" : [ "ISBN:0716731363" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_yeast", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "juxtamembrane" @@ -6909,7 +6923,7 @@ "val" : "Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction.", "xrefs" : [ "ISBN:0198506732" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_pombe", "http://purl.obolibrary.org/obo/go#goslim_yeast", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_pombe", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" @@ -6924,7 +6938,7 @@ "val" : "The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.", "xrefs" : [ "GOC:go_curators" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "protein anabolism" @@ -7063,7 +7077,7 @@ "xrefs" : [ "GOC:dos", "GOC:dph", "GOC:jl", "GOC:mah" ] }, "comments" : [ "Note that this term should not be used for direct annotation. It should be possible to make a more specific annotation to one of the children of this term, for e.g. to transmembrane transport, to microtubule-based transport or to vesicle-mediated transport." ], - "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "single-organism transport" @@ -8070,7 +8084,7 @@ "val" : "Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538).", "xrefs" : [ "GOC:mah", "GOC:mtg_apoptosis", "PMID:25236395" ] }, - "comments" : [ "This term should not be used for direct annotation, it is currently kept in GO as a placeholder for describing cell death phenotypes in uPHENO. When information is provided on a programmed cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'). Unintentional cell death, i.e. cell death caused by injury, ageing, or cell phenotypes observed as a result of a pathological mutation in an essential gene should NOT be annotated using GO terms." ], + "comments" : [ "This term should not be used for direct annotation, it is currently kept in GO as a placeholder for describing cell death phenotypes in uPHENO. When information is provided on a programmed cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'). Unintentional cell death, i.e. cell death caused by injury, ageing, or cell phenotypes observed as a result of a pathological mutation in an essential gene should NOT be annotated using GO terms." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", @@ -8474,7 +8488,7 @@ "xrefs" : [ "GOC:lr", "GOC:mtg_apoptosis" ] }, "comments" : [ "Note that this term should be used to annotate gene products in the organism undergoing the programmed cell death. To annotate genes in another organism whose products modulate programmed cell death in a host organism, consider the term 'modulation by symbiont of host programmed cell death ; GO:0052040'. Also, note that 'programmed cell death ; GO:0012501' should be used to refer to instances of caspase-independent cell death mechanisms, in the absence of further indications on the process taking place. At present, caspase-independent cell death is not yet represented in GO due to the lack of consensus and in-depth research on the topic. 'programmed cell death ; GO:0012501' may also be used to annotate gene products in taxa where apoptosis as defined in GO:0006915 does not occur, such as plants. You may also consider these specific children: GO:0097468 'programmed cell death in response to reactive oxygen species' (with descendants GO:0010421 'hydrogen peroxide-mediated programmed cell death' and GO:0010343 'singlet oxygen-mediated programmed cell death'), and GO:0009626 'plant-type hypersensitive response' and its children." ], - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "regulated cell death" @@ -9198,7 +9212,7 @@ "xrefs" : [ "GOC:mtg_signal", "GOC:mtg_signaling_feb11", "GOC:signaling" ] }, "comments" : [ "Note that a signal is any variable property or parameter that serves to convey information, and may be a physical entity such as a gene product or small molecule, a photon, or a change in state such as movement or voltage change." ], - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pombe", "http://purl.obolibrary.org/obo/go#goslim_yeast", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pombe", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "biological signaling" @@ -9264,7 +9278,7 @@ "val" : "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon.", "xrefs" : [ "GOC:jl", "GOC:mah", "http://www.cogsci.princeton.edu/~wn/" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cell projection organisation" @@ -9899,7 +9913,7 @@ "val" : "A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues.", "xrefs" : [ "GOC:BHF", "GOC:mah", "GOC:rph", "NIF_Subcellular:nlx_subcell_20090513", "PMID:21123617", "PMID:28089324" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "proteinaceous extracellular matrix" @@ -11159,7 +11173,7 @@ "val" : "A prolongation or process extending from a cell, e.g. a flagellum or axon.", "xrefs" : [ "GOC:jl", "http://www.cogsci.princeton.edu/~wn/" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "cell process" @@ -11215,7 +11229,7 @@ "val" : "The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.", "xrefs" : [ "GOC:mah" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_pir" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_pir" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "biopolymer metabolic process", @@ -11231,6 +11245,9 @@ "val" : "multicellular organismal macromolecule metabolic process" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/26424" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0034960" }, { @@ -11267,7 +11284,7 @@ "val" : "Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane.", "xrefs" : [ "GOC:go_curators" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "xrefs" : [ { "val" : "NIF_Subcellular:sao1539965131" }, { @@ -11568,12 +11585,15 @@ "val" : "The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.", "xrefs" : [ "GOC:go_curators", "http://www.metacyc.org" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_pir" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_pir" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "primary metabolism" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/26424" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] @@ -12338,12 +12358,15 @@ "val" : "The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.", "xrefs" : [ "GO_REF:0000021" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_plant" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_plant" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "development of an anatomical structure" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/26424" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] @@ -12371,7 +12394,7 @@ "val" : "Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another.", "xrefs" : [ "GOC:dgh", "GOC:dph", "GOC:isa_complete", "GOC:mlg" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cell locomotion" @@ -12665,7 +12688,7 @@ "xrefs" : [ "GOC:ai", "GOC:bf" ] }, "comments" : [ "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ], - "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_manually_annotate", "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_manually_annotate", "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "physiological response to stimulus" @@ -13044,7 +13067,7 @@ "val" : "A compound molecular function in which an effector function is controlled by one or more regulatory components.", "xrefs" : [ "GOC:dos", "GOC:pdt" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_manually_annotate", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_manually_annotate", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "molecular_function" @@ -13155,7 +13178,7 @@ "val" : "A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.", "xrefs" : [ "GOC:dph", "GOC:tb" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_pombe", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_pombe", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cellular membrane organisation" @@ -13277,7 +13300,7 @@ "val" : "The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex.", "xrefs" : [ "GOC:jl" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_pombe", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_pombe", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cellular protein complex assembly" @@ -13487,6 +13510,7 @@ "val" : "The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon.", "xrefs" : [ "GOC:mah" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "organic molecular entity metabolic process" @@ -13498,6 +13522,9 @@ "val" : "organic substance metabolism" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/26424" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "mah" }, { @@ -13697,7 +13724,7 @@ "type" : "CLASS", "meta" : { "definition" : { - "val" : "The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures.", + "val" : "The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures.", "xrefs" : [ "GOC:pdt" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon" ], @@ -13925,7 +13952,7 @@ "val" : "Reactions triggered in response to the presence of another organism that act to protect the cell or organism from damage caused by that organism.", "xrefs" : [ "GOC:dos" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "defence response incompatible interaction" @@ -14258,6 +14285,9 @@ "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/24200" + }, { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/26424" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "kmv" @@ -14443,6 +14473,29 @@ "val" : "biological_process" } ] } + }, { + "id" : "http://purl.obolibrary.org/obo/GO_0140546", + "lbl" : "defense response to symbiont", + "type" : "CLASS", + "meta" : { + "definition" : { + "val" : "Reactions triggered in response to the presence of a symbiont that act to protect or prevent damage to the host.", + "xrefs" : [ "GOC:pg" ] + }, + "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/20261" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", + "val" : "pg" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", + "val" : "2020-11-11T17:19:06Z" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "biological_process" + } ] + } }, { "id" : "http://purl.obolibrary.org/obo/GO_1901576", "lbl" : "organic substance biosynthetic process", @@ -16111,47 +16164,6 @@ "val" : "quality" } ] } - }, { - "id" : "http://purl.obolibrary.org/obo/PATO_0000068", - "lbl" : "qualitative", - "type" : "CLASS", - "meta" : { - "comments" : [ "TODO: define this or obsolete it and move children somewhere else." ], - "basicPropertyValues" : [ { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", - "val" : "quality" - } ] - } - }, { - "id" : "http://purl.obolibrary.org/obo/PATO_0000069", - "lbl" : "deviation (from_normal)", - "type" : "CLASS", - "meta" : { - "definition" : { - "val" : "A quality inhering in a bearer by virtue of the whether the bearer differs from normal or average.", - "xrefs" : [ "PATOC:GVG" ] - }, - "subsets" : [ "http://purl.obolibrary.org/obo/pato#attribute_slim" ], - "basicPropertyValues" : [ { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", - "val" : "quality" - } ] - } - }, { - "id" : "http://purl.obolibrary.org/obo/PATO_0000117", - "lbl" : "size", - "type" : "CLASS", - "meta" : { - "definition" : { - "val" : "A morphology quality inhering in a bearer by virtue of the bearer's physical magnitude.", - "xrefs" : [ "WordNet:WordNet" ] - }, - "subsets" : [ "http://purl.obolibrary.org/obo/pato#attribute_slim", "http://purl.obolibrary.org/obo/pato#scalar_slim" ], - "basicPropertyValues" : [ { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", - "val" : "quality" - } ] - } }, { "id" : "http://purl.obolibrary.org/obo/PATO_0000141", "lbl" : "structure", @@ -16240,65 +16252,6 @@ "val" : "quality" } ] } - }, { - "id" : "http://purl.obolibrary.org/obo/PATO_0000461", - "lbl" : "normal", - "type" : "CLASS", - "meta" : { - "definition" : { - "val" : "A quality inhering in a bearer by virtue of the bearer's exhibiting no deviation from normal or average.", - "xrefs" : [ "PATOC:GVG" ] - }, - "subsets" : [ "http://purl.obolibrary.org/obo/pato#abnormal_slim", "http://purl.obolibrary.org/obo/pato#mpath_slim", "http://purl.obolibrary.org/obo/pato#value_slim" ], - "synonyms" : [ { - "pred" : "hasRelatedSynonym", - "val" : "average" - } ], - "basicPropertyValues" : [ { - "pred" : "http://purl.obolibrary.org/obo/RO_0002604", - "val" : "http://purl.obolibrary.org/obo/PATO_0000460" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", - "val" : "quality" - } ] - } - }, { - "id" : "http://purl.obolibrary.org/obo/PATO_0000586", - "lbl" : "increased size", - "type" : "CLASS", - "meta" : { - "definition" : { - "val" : "A size quality which is relatively high.", - "xrefs" : [ "PATOC:GVG" ] - }, - "subsets" : [ "http://purl.obolibrary.org/obo/pato#value_slim" ], - "synonyms" : [ { - "pred" : "hasRelatedSynonym", - "val" : "big" - }, { - "pred" : "hasRelatedSynonym", - "val" : "enlarged" - }, { - "pred" : "hasRelatedSynonym", - "val" : "expanded" - }, { - "pred" : "hasRelatedSynonym", - "val" : "great" - }, { - "pred" : "hasRelatedSynonym", - "val" : "large" - } ], - "basicPropertyValues" : [ { - "pred" : "http://purl.obolibrary.org/obo/RO_0002604", - "val" : "http://purl.obolibrary.org/obo/PATO_0000587" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", - "val" : "PATO:0001202" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", - "val" : "quality" - } ] - } }, { "id" : "http://purl.obolibrary.org/obo/PATO_0000947", "lbl" : "elliptic", @@ -17008,52 +16961,6 @@ "val" : "quality" } ] } - }, { - "id" : "http://purl.obolibrary.org/obo/PATO_0002300", - "lbl" : "increased quality", - "type" : "CLASS", - "meta" : { - "definition" : { - "val" : "A quality that has a value that is increased compared to normal or average.", - "xrefs" : [ "PATOC:GVG" ] - }, - "basicPropertyValues" : [ { - "pred" : "http://purl.obolibrary.org/obo/RO_0002604", - "val" : "http://purl.obolibrary.org/obo/PATO_0002301" - }, { - "pred" : "http://purl.org/dc/terms/contributor", - "val" : "https://orcid.org/0000-0002-2061-091X" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", - "val" : "2011-06-16T06:39:43Z" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", - "val" : "quality" - } ] - } - }, { - "id" : "http://purl.obolibrary.org/obo/PATO_0002305", - "lbl" : "increased object quality", - "type" : "CLASS", - "meta" : { - "definition" : { - "val" : "A quality of an object that has a value that is increased compared to normal or average.", - "xrefs" : [ "PATOC:GVG" ] - }, - "basicPropertyValues" : [ { - "pred" : "http://purl.obolibrary.org/obo/RO_0002604", - "val" : "http://purl.obolibrary.org/obo/PATO_0002303" - }, { - "pred" : "http://purl.org/dc/terms/contributor", - "val" : "https://orcid.org/0000-0002-2061-091X" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", - "val" : "2011-06-16T06:54:01Z" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", - "val" : "quality" - } ] - } }, { "id" : "http://purl.obolibrary.org/obo/PATO_0002318", "lbl" : "superelliptic", @@ -17161,6 +17068,28 @@ "val" : "quality" } ] } + }, { + "id" : "http://purl.obolibrary.org/obo/PATO_0040072", + "lbl" : "high nuclear/cytoplasmic ratio", + "type" : "CLASS", + "meta" : { + "definition" : { + "val" : "A quality inhering in a cell by virtue of the cell having a high nuclear/cytoplasmic ratio.", + "xrefs" : [ "Wikipedia:NC_ratio&oldid=931936284", "http://lymerick.net/blood-cells.pdf" ] + }, + "comments" : [ "A high nuclear/cytolasmic ratio is 70% or higher." ], + "synonyms" : [ { + "pred" : "hasExactSynonym", + "val" : "high N:C ratio" + } ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", + "val" : "http://orcid.org/0000-0001-5208-3432" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "quality" + } ] + } }, { "id" : "http://purl.obolibrary.org/obo/PATO_0070044", "lbl" : "anatomical structure quality", @@ -22110,6 +22039,9 @@ "val" : "inverse of develops from" }, "subsets" : [ "http://purl.obolibrary.org/obo/RO_0002259" ], + "xrefs" : [ { + "val" : "RO:0002203" + } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000114", "val" : "http://purl.obolibrary.org/obo/IAO_0000125" @@ -22122,6 +22054,12 @@ }, { "pred" : "http://purl.obolibrary.org/obo/IAO_0000117", "val" : "https://orcid.org/0000-0003-1980-3228" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "uberon" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#shorthand", + "val" : "develops_into" } ] } }, { @@ -27087,7 +27025,7 @@ "val" : "zygote", "xrefs" : [ "VHOG:0000745" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "zygotum", "xrefs" : [ "Wikipedia:Zygote" ] @@ -27364,7 +27302,7 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#efo_slim", "http://purl.obolibrary.org/obo/uberon/core#major_organ", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "regio oralis", "xrefs" : [ "BTO:0004698", "FMA:49184", "FMA:TA" ] @@ -27372,7 +27310,7 @@ "pred" : "hasNarrowSynonym", "val" : "adult mouth" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "cavital oralis", "xrefs" : [ "Wikipedia:Mouth" ] @@ -28390,8 +28328,6 @@ "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#common_anatomy", "http://purl.obolibrary.org/obo/uberon/core#upper_level" ], "xrefs" : [ { "val" : "FBbt:00007277" - }, { - "val" : "IDOMAL:0002461" }, { "val" : "VHOG:0001737" } ], @@ -29609,7 +29545,7 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "systema cardiovasculare", "xrefs" : [ "Wikipedia:Circulatory_system" ] @@ -29618,6 +29554,8 @@ "val" : "AAO:0000959" }, { "val" : "CALOHA:TS-2103" + }, { + "val" : "MESH:D002319" }, { "val" : "VHOG:0001248" }, { @@ -29675,7 +29613,7 @@ "pred" : "hasExactSynonym", "val" : "musculature" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "musculi", "xrefs" : [ "FMA:32558", "FMA:TA" ] @@ -29749,7 +29687,7 @@ "val" : "The nervous system is an organ system containing predominantly neuron and glial cells. In bilaterally symmetrical organism, it is arranged in a network of tree-like structures connected to a central body. The main functions of the nervous system are to regulate and control body functions, and to receive sensory input, process this information, and generate behavior [CUMBO].", "xrefs" : [ "BIRNLEX:844", "ISBN:0-14-051288-8", "ISBN:3110148986", "NLM:nervous+system", "WB:rynl", "Wikipedia:Nervous_system", "ZFIN:curator" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#cumbo", "http://purl.obolibrary.org/obo/uberon/core#efo_slim", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], + "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#cumbo", "http://purl.obolibrary.org/obo/uberon/core#efo_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "neurological system", @@ -29759,7 +29697,7 @@ "val" : "nerve net", "xrefs" : [ "Wikipedia:Nerve_net" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "systema nervosum", "xrefs" : [ "Wikipedia:Nervous_system" ] @@ -29822,6 +29760,9 @@ "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_6040" + }, { + "pred" : "http://purl.obolibrary.org/obo/RO_0002175", + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" }, { "pred" : "http://purl.obolibrary.org/obo/UBPROP_0000001", "val" : "A regulatory system of the body that consists of neurons and neuroglial cells. The nervous system is divided into two parts, the central nervous system (CNS) and the peripheral nervous system (PNS). (Source: BioGlossary, www.Biology-Text.com)[TAO]" @@ -29857,13 +29798,13 @@ "val" : "The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the neural tube derivatives: the brain and spinal cord. In invertebrates it includes central ganglia plus nerve cord.", "xrefs" : [ "GO:0021551", "http://www.frontiersinzoology.com/content/7/1/29", "https://sourceforge.net/p/geneontology/ontology-requests/11422/" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#cumbo", "http://purl.obolibrary.org/obo/uberon/core#efo_slim", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], + "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#cumbo", "http://purl.obolibrary.org/obo/uberon/core#efo_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], "synonyms" : [ { "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003000", "pred" : "hasExactSynonym", "val" : "CNS" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "systema nervosum centrale", "xrefs" : [ "FMA:55675", "FMA:TA" ] @@ -29934,6 +29875,9 @@ "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099" + }, { + "pred" : "http://purl.obolibrary.org/obo/RO_0002175", + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" }, { "pred" : "http://purl.obolibrary.org/obo/UBPROP_0000001", "val" : "Part of the nervous system which includes the brain and spinal cord.[AAO]" @@ -30025,7 +29969,7 @@ "pred" : "hasRelatedSynonym", "val" : "presumptive central nervous system" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "tubus neuralis", "xrefs" : [ "Wikipedia:Neural_tube" ] @@ -30396,6 +30340,8 @@ "val" : "FMA:45615" }, { "val" : "MA:0000917" + }, { + "val" : "MESH:D041981" }, { "val" : "NCIT:C34082" }, { @@ -30578,7 +30524,7 @@ "val" : "vascular tree organ region", "xrefs" : [ "FMA:50722" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "vas sanguineum", "xrefs" : [ "Wikipedia:Blood_vessel" ] @@ -30933,6 +30879,8 @@ "val" : "MA:0002986" }, { "val" : "MAT:0000148" + }, { + "val" : "MESH:D013131" }, { "val" : "MIAA:0000148" }, { @@ -31152,7 +31100,7 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "cavitas thoracis", "xrefs" : [ "Wikipedia:Thoracic_cavity" ] @@ -31320,7 +31268,7 @@ "val" : "notocord", "xrefs" : [ "ZFA:0000135" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "notochorda", "xrefs" : [ "Wikipedia:Notochord" ] @@ -31433,7 +31381,7 @@ "pred" : "hasRelatedSynonym", "val" : "somitic mesoderm" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "somitus", "xrefs" : [ "Wikipedia:Somite" ] @@ -31529,7 +31477,7 @@ "val" : "NC", "xrefs" : [ "XAO:0000048" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "crista neuralis", "xrefs" : [ "Wikipedia:Neural_crest" ] @@ -31623,7 +31571,7 @@ "pred" : "hasExactSynonym", "val" : "neuroectoderm" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "epithelium tubi neuralis; neuroectoderma", "xrefs" : [ "Wikipedia:Neuroectoderm" ] @@ -31702,12 +31650,12 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#efo_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "medulla ossea", "xrefs" : [ "BTO:0000141", "FMA:9608" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "medulla ossium", "xrefs" : [ "BTO:0000141", "Wikipedia:Bone_marrow" ] @@ -32165,7 +32113,7 @@ "val" : "ectoblast", "xrefs" : [ "MP:0003886" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "epiblastus", "xrefs" : [ "Wikipedia:Epiblast" ] @@ -32424,7 +32372,7 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "lamina neuralis", "xrefs" : [ "Wikipedia:Neural_plate" ] @@ -32502,7 +32450,7 @@ "val" : "somitic mesoderm", "xrefs" : [ "ISBN:9780878932504" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "mesoderma paraxiale", "xrefs" : [ "Wikipedia:Paraxial_mesoderm" ] @@ -32578,7 +32526,7 @@ "val" : "lateral plate mesenchyme", "xrefs" : [ "EHDAA2:0000919" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "mesoderma laminae lateralis", "xrefs" : [ "Wikipedia:Lateral_plate_mesoderm" ] @@ -32699,7 +32647,7 @@ "val" : "sclerotomes", "xrefs" : [ "TAO:0001080" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "sclerotomus", "xrefs" : [ "Wikipedia:Sclerotome" ] @@ -32818,7 +32766,7 @@ "pred" : "hasExactSynonym", "val" : "portion of mesenchyme tissue" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "mesenchyma", "xrefs" : [ "Wikipedia:Mesenchyme" ] @@ -33461,7 +33409,7 @@ "val" : "An endothelium that lines the blood vasculature. Other endothelia may line lymph vessels, the heart.", "xrefs" : [ "https://orcid.org/0000-0002-6601-2165" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], + "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], "xrefs" : [ { "val" : "BTO:0000766" }, { @@ -33480,6 +33428,9 @@ "val" : "ZFA:0005257" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/RO_0002175", + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "uberon" } ] @@ -34359,7 +34310,7 @@ "val" : "basement membrane of connective tissue", "xrefs" : [ "FMA:63872" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "membrana basalis", "xrefs" : [ "Wikipedia:Basement_membrane" ] @@ -34431,7 +34382,7 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "skeleton axiale", "xrefs" : [ "Wikipedia:Axial_skeleton" ] @@ -35575,7 +35526,7 @@ "val" : "A subdivision of an anatomical system.", "xrefs" : [ "http://orcid.org/0000-0002-6601-2165" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#common_anatomy", "http://purl.obolibrary.org/obo/uberon/core#upper_level" ], + "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#common_anatomy", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#upper_level" ], "xrefs" : [ { "val" : "FBbt:00007330" }, { @@ -35592,6 +35543,9 @@ }, { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_4751" + }, { + "pred" : "http://purl.obolibrary.org/obo/RO_0002175", + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "uberon" @@ -35860,7 +35814,7 @@ "val" : "The region of the organism associated with the visceral organs.", "xrefs" : [ "AEO:0000103" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#non_informative" ], + "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#non_informative" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "body", @@ -35880,9 +35834,6 @@ "val" : "FMA:231424" } ], "basicPropertyValues" : [ { - "pred" : "http://purl.obolibrary.org/obo/RO_0002175", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" - }, { "pred" : "http://purl.obolibrary.org/obo/UBPROP_0000001", "val" : "Cardinal body part, which consists of a maximal set of diverse subclasses of organ and organ part spatially associated with the vertebral column and ribcage. Examples: There is only one body proper[FMA:231424]." }, { @@ -36314,8 +36265,10 @@ "val" : "OBSOLETE A relation between a cell and molecule or complex such that every instance of the cell has a high number of instances of that molecule expressed on the cell surface. For the formal definition, see Masci et al (PMID:19243617).", "xrefs" : [ "PMID:19243617" ] }, - "comments" : [ "Replaced with RO:0015015, see https://github.com/obophenotype/cell-ontology/issues/1481" ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/obophenotype/cell-ontology/issues/1481" + }, { "pred" : "http://purl.obolibrary.org/obo/IAO_0100001", "val" : "http://purl.obolibrary.org/obo/RO_0015015" } ], @@ -36330,8 +36283,10 @@ "val" : "OBSOLETE A relation between a cell and molecule or complex such that every instance of the cell has a low number of instances of that molecule expressed on the cell surface. For the formal definition, see Masci et al (PMID:19243617).", "xrefs" : [ "PMID:19243617" ] }, - "comments" : [ "Replaced with RO:0015016, see https://github.com/obophenotype/cell-ontology/issues/1481" ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/obophenotype/cell-ontology/issues/1481" + }, { "pred" : "http://purl.obolibrary.org/obo/IAO_0100001", "val" : "http://purl.obolibrary.org/obo/RO_0015016" } ], @@ -36561,13 +36516,12 @@ "lbl" : "transitively anteriorly connected to", "type" : "PROPERTY", "meta" : { - "definition" : { - "val" : ".", - "xrefs" : [ "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" ] - }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "uberon" + }, { + "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", + "val" : "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" } ] } }, { @@ -36575,13 +36529,12 @@ "lbl" : "transitively distally connected to", "type" : "PROPERTY", "meta" : { - "definition" : { - "val" : ".", - "xrefs" : [ "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" ] - }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "uberon" + }, { + "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", + "val" : "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" } ] } }, { @@ -36589,13 +36542,12 @@ "lbl" : "transitively proximally connected to", "type" : "PROPERTY", "meta" : { - "definition" : { - "val" : ".", - "xrefs" : [ "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" ] - }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "uberon" + }, { + "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", + "val" : "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" } ] } }, { @@ -37828,11 +37780,11 @@ }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000542", "pred" : "http://purl.obolibrary.org/obo/BFO_0000051", - "obj" : "http://purl.obolibrary.org/obo/CL_0017505" + "obj" : "http://purl.obolibrary.org/obo/GO_0000792" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000542", - "pred" : "http://purl.obolibrary.org/obo/BFO_0000051", - "obj" : "http://purl.obolibrary.org/obo/GO_0000792" + "pred" : "http://purl.obolibrary.org/obo/RO_0000053", + "obj" : "http://purl.obolibrary.org/obo/PATO_0040072" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000542", "pred" : "http://purl.obolibrary.org/obo/RO_0002202", @@ -37859,10 +37811,6 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0000547", "pred" : "http://purl.obolibrary.org/obo/BFO_0000051", "obj" : "http://purl.obolibrary.org/obo/CL_0017503" - }, { - "sub" : "http://purl.obolibrary.org/obo/CL_0000547", - "pred" : "http://purl.obolibrary.org/obo/BFO_0000051", - "obj" : "http://purl.obolibrary.org/obo/CL_0017505" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000547", "pred" : "http://purl.obolibrary.org/obo/BFO_0000051", @@ -37911,6 +37859,10 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0000547", "pred" : "http://purl.obolibrary.org/obo/CL_4030046", "obj" : "http://purl.obolibrary.org/obo/PR_000002978" + }, { + "sub" : "http://purl.obolibrary.org/obo/CL_0000547", + "pred" : "http://purl.obolibrary.org/obo/RO_0000053", + "obj" : "http://purl.obolibrary.org/obo/PATO_0040072" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000547", "pred" : "http://purl.obolibrary.org/obo/RO_0002104", @@ -39781,14 +39733,6 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0017504", "pred" : "http://purl.obolibrary.org/obo/RO_0000053", "obj" : "http://purl.obolibrary.org/obo/PATO_0070047" - }, { - "sub" : "http://purl.obolibrary.org/obo/CL_0017505", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/GO_0005634" - }, { - "sub" : "http://purl.obolibrary.org/obo/CL_0017505", - "pred" : "http://purl.obolibrary.org/obo/RO_0000053", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000586" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0017508", "pred" : "is_a", @@ -41057,7 +41001,7 @@ "obj" : "http://purl.obolibrary.org/obo/GO_0042060" }, { "sub" : "http://purl.obolibrary.org/obo/GO_0007596", - "pred" : "http://purl.obolibrary.org/obo/RO_0004008", + "pred" : "http://purl.obolibrary.org/obo/RO_0002588", "obj" : "http://purl.obolibrary.org/obo/UBERON_0010210" }, { "sub" : "http://purl.obolibrary.org/obo/GO_0007599", @@ -42178,7 +42122,7 @@ }, { "sub" : "http://purl.obolibrary.org/obo/GO_0045087", "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/GO_0098542" + "obj" : "http://purl.obolibrary.org/obo/GO_0140546" }, { "sub" : "http://purl.obolibrary.org/obo/GO_0045190", "pred" : "is_a", @@ -43239,6 +43183,10 @@ "sub" : "http://purl.obolibrary.org/obo/GO_0140352", "pred" : "http://purl.obolibrary.org/obo/RO_0002339", "obj" : "http://purl.obolibrary.org/obo/GO_0005576" + }, { + "sub" : "http://purl.obolibrary.org/obo/GO_0140546", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/GO_0098542" }, { "sub" : "http://purl.obolibrary.org/obo/GO_1901576", "pred" : "is_a", @@ -43475,18 +43423,6 @@ "sub" : "http://purl.obolibrary.org/obo/PATO_0000052", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/PATO_0000051" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0000068", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000001" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0000069", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000068" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0000117", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000051" }, { "sub" : "http://purl.obolibrary.org/obo/PATO_0000141", "pred" : "is_a", @@ -43503,18 +43439,6 @@ "sub" : "http://purl.obolibrary.org/obo/PATO_0000411", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/PATO_0000947" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0000461", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000068" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0000586", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000117" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0000586", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0002305" }, { "sub" : "http://purl.obolibrary.org/obo/PATO_0000947", "pred" : "is_a", @@ -43671,22 +43595,6 @@ "sub" : "http://purl.obolibrary.org/obo/PATO_0002299", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/PATO_0002078" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0002300", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000069" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0002300", - "pred" : "http://purl.obolibrary.org/obo/RO_0015007", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000461" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0002305", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0001241" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0002305", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0002300" }, { "sub" : "http://purl.obolibrary.org/obo/PATO_0002318", "pred" : "is_a", @@ -43707,6 +43615,10 @@ "sub" : "http://purl.obolibrary.org/obo/PATO_0015006", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/PATO_0000141" + }, { + "sub" : "http://purl.obolibrary.org/obo/PATO_0040072", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/PATO_0001396" }, { "sub" : "http://purl.obolibrary.org/obo/PATO_0070044", "pred" : "is_a", @@ -49257,15 +49169,15 @@ "restrictions" : [ { "propertyId" : "http://purl.obolibrary.org/obo/BFO_0000051", "fillerId" : "http://purl.obolibrary.org/obo/CL_0017500" - }, { - "propertyId" : "http://purl.obolibrary.org/obo/BFO_0000051", - "fillerId" : "http://purl.obolibrary.org/obo/CL_0017505" }, { "propertyId" : "http://purl.obolibrary.org/obo/BFO_0000051", "fillerId" : "http://purl.obolibrary.org/obo/GO_0000792" }, { "propertyId" : "http://purl.obolibrary.org/obo/RO_0000053", "fillerId" : "http://purl.obolibrary.org/obo/PATO_0001407" + }, { + "propertyId" : "http://purl.obolibrary.org/obo/RO_0000053", + "fillerId" : "http://purl.obolibrary.org/obo/PATO_0040072" } ] }, { "definedClassId" : "http://purl.obolibrary.org/obo/CL_0000547", @@ -49273,9 +49185,6 @@ "restrictions" : [ { "propertyId" : "http://purl.obolibrary.org/obo/BFO_0000051", "fillerId" : "http://purl.obolibrary.org/obo/CL_0017503" - }, { - "propertyId" : "http://purl.obolibrary.org/obo/BFO_0000051", - "fillerId" : "http://purl.obolibrary.org/obo/CL_0017505" }, { "propertyId" : "http://purl.obolibrary.org/obo/BFO_0000051", "fillerId" : "http://purl.obolibrary.org/obo/GO_0005730" @@ -49315,6 +49224,9 @@ }, { "propertyId" : "http://purl.obolibrary.org/obo/RO_0000053", "fillerId" : "http://purl.obolibrary.org/obo/PATO_0002505" + }, { + "propertyId" : "http://purl.obolibrary.org/obo/RO_0000053", + "fillerId" : "http://purl.obolibrary.org/obo/PATO_0040072" }, { "propertyId" : "http://purl.obolibrary.org/obo/RO_0002104", "fillerId" : "http://purl.obolibrary.org/obo/PR_000001945" @@ -50341,13 +50253,6 @@ "propertyId" : "http://purl.obolibrary.org/obo/RO_0000053", "fillerId" : "http://purl.obolibrary.org/obo/PATO_0070047" } ] - }, { - "definedClassId" : "http://purl.obolibrary.org/obo/CL_0017505", - "genusIds" : [ "http://purl.obolibrary.org/obo/GO_0005634" ], - "restrictions" : [ { - "propertyId" : "http://purl.obolibrary.org/obo/RO_0000053", - "fillerId" : "http://purl.obolibrary.org/obo/PATO_0000586" - } ] }, { "definedClassId" : "http://purl.obolibrary.org/obo/CL_1001610", "genusIds" : [ "http://purl.obolibrary.org/obo/CL_0000988" ], @@ -50765,7 +50670,7 @@ "definedClassId" : "http://purl.obolibrary.org/obo/GO_0007596", "genusIds" : [ "http://purl.obolibrary.org/obo/GO_0050817" ], "restrictions" : [ { - "propertyId" : "http://purl.obolibrary.org/obo/RO_0004008", + "propertyId" : "http://purl.obolibrary.org/obo/RO_0002588", "fillerId" : "http://purl.obolibrary.org/obo/UBERON_0010210" } ] }, { @@ -51777,27 +51682,6 @@ "propertyId" : "http://purl.obolibrary.org/obo/RO_0002213", "fillerId" : "http://purl.obolibrary.org/obo/GO_0048870" } ] - }, { - "definedClassId" : "http://purl.obolibrary.org/obo/PATO_0000586", - "genusIds" : [ "http://purl.obolibrary.org/obo/PATO_0000117" ], - "restrictions" : [ { - "propertyId" : "http://purl.obolibrary.org/obo/RO_0015007", - "fillerId" : "http://purl.obolibrary.org/obo/PATO_0000461" - } ] - }, { - "definedClassId" : "http://purl.obolibrary.org/obo/PATO_0002300", - "genusIds" : [ "http://purl.obolibrary.org/obo/PATO_0000001" ], - "restrictions" : [ { - "propertyId" : "http://purl.obolibrary.org/obo/RO_0015007", - "fillerId" : "http://purl.obolibrary.org/obo/PATO_0000461" - } ] - }, { - "definedClassId" : "http://purl.obolibrary.org/obo/PATO_0002305", - "genusIds" : [ "http://purl.obolibrary.org/obo/PATO_0001241" ], - "restrictions" : [ { - "propertyId" : "http://purl.obolibrary.org/obo/RO_0015007", - "fillerId" : "http://purl.obolibrary.org/obo/PATO_0000461" - } ] }, { "definedClassId" : "http://purl.obolibrary.org/obo/PR_000029032", "genusIds" : [ "http://purl.obolibrary.org/obo/PR_000000001" ], diff --git a/subsets/blood_and_immune_upper_slim.obo b/subsets/blood_and_immune_upper_slim.obo index dfabdc25d..35057603f 100644 --- a/subsets/blood_and_immune_upper_slim.obo +++ b/subsets/blood_and_immune_upper_slim.obo @@ -1,5 +1,5 @@ format-version: 1.2 -data-version: cl/releases/2024-01-04/subsets/blood_and_immune_upper_slim.owl +data-version: cl/releases/2024-02-13/subsets/blood_and_immune_upper_slim.owl subsetdef: abnormal_slim "" subsetdef: added_for_HCA "" subsetdef: attribute_slim "" @@ -31,6 +31,7 @@ subsetdef: goslim_mouse "" subsetdef: goslim_pir "" subsetdef: goslim_plant "" subsetdef: goslim_pombe "" +subsetdef: goslim_prokaryote "" subsetdef: goslim_synapse "" subsetdef: goslim_yeast "" subsetdef: grouping_class "" @@ -49,7 +50,6 @@ subsetdef: non_informative "" subsetdef: organ_slim "" subsetdef: pheno_slim "" subsetdef: phenotype_rcn "" -subsetdef: prokaryote_subset "" subsetdef: ro-eco "" subsetdef: RO:0002259 "" subsetdef: scalar_slim "" @@ -62,7 +62,6 @@ subsetdef: vertebrate_core "" synonymtypedef: blast_name "" synonymtypedef: COMPARATIVE_PREFERRED "" synonymtypedef: DEPRECATED "" -synonymtypedef: DUBIOUS "" synonymtypedef: equivalent_name "" synonymtypedef: genbank_common_name "" synonymtypedef: Gene-based "" @@ -71,13 +70,14 @@ synonymtypedef: HUMAN_PREFERRED "" synonymtypedef: HUMAN_PREFERRED "preferred term when talking about an instance of this class in Homo sapiens" synonymtypedef: in_part "" synonymtypedef: INCONSISTENT "" -synonymtypedef: LATIN "" synonymtypedef: LATIN "latin term" synonymtypedef: MISSPELLING "a mis-spelling that is in common use and thus recorded" synonymtypedef: NON_MAMMAL "" synonymtypedef: OMO:0003000 "abbreviation" +synonymtypedef: OMO:0003002 "" synonymtypedef: OMO:0003003 "" synonymtypedef: OMO:0003004 "plural form" +synonymtypedef: OMO:0003011 "" synonymtypedef: PENDING_REVIEW "" synonymtypedef: PLURAL "plural term" synonymtypedef: PRO-short-label "" @@ -88,7 +88,7 @@ synonymtypedef: synonym "" synonymtypedef: SYSTEMATIC "" synonymtypedef: systematic_synonym "" ontology: cl/subsets/blood_and_immune_upper_slim -property_value: owl:versionInfo "2024-01-04" xsd:string +property_value: owl:versionInfo "2024-02-13" xsd:string [Term] id: BFO:0000002 @@ -144,6 +144,7 @@ id: CL:0000000 name: cell def: "A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane." [CARO:mah] comment: The definition of cell is intended to represent all cells, and thus a cell is defined as a material entity and not an anatomical structure, which implies that it is part of an organism (or the entirety of one). +subset: cellxgene_subset subset: ubprop:upper_level xref: CALOHA:TS-2035 xref: FBbt:00007002 @@ -171,6 +172,7 @@ id: CL:0000034 name: stem cell def: "A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells." [GOC:tfm, MESH:D013234] comment: This term applies to metazoan. For plant stem cells, consider using PO:0004011 ‘initial cell’ or its parent PO:0004010 ‘meristematic cell’. +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "animal stem cell" EXACT [] @@ -189,6 +191,7 @@ name: hematopoietic stem cell def: "A stem cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system. Hematopoietic stem cells lack cell markers of effector cells (lin-negative). Lin-negative is defined by lacking one or more of the following cell surface markers: CD2, CD3 epsilon, CD4, CD5 ,CD8 alpha chain, CD11b, CD14, CD19, CD20, CD56, ly6G, ter119." [GOC:add, GOC:dsd, GOC:tfm, http://en.wikipedia.org/wiki/Hematopoietic_stem_cell, PMID:19022770] comment: Markers differ between species, and two sets of markers have been described for mice. HSCs are reportedly CD34-positive, CD45-positive, CD48-negative, CD150-positive, CD133-positive, and CD244-negative. subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "blood forming stem cell" EXACT [] synonym: "colony forming unit hematopoietic" RELATED [] @@ -238,6 +241,7 @@ id: CL:0000038 name: erythroid progenitor cell def: "A progenitor cell committed to the erythroid lineage." [GOC:add, ISBN:0721601464] subset: blood_and_immune_upper_slim +subset: cellxgene_subset synonym: "BFU-E" RELATED OMO:0003000 [] synonym: "blast forming unit erythroid" RELATED [] synonym: "burst forming unit erythroid" RELATED [] @@ -295,6 +299,7 @@ id: CL:0000049 name: common myeloid progenitor def: "A progenitor cell committed to myeloid lineage, including the megakaryocyte and erythroid lineages." [GOC:add, ISBN:0878932437, MESH:D023461] comment: This cell type is intended to be compatible with any vertebrate common myeloid progenitor. For mammalian CMP known to be CD34-positive, please use the term 'common myeloid progenitor, CD34-positive' (CL_0001059). +subset: cellxgene_subset subset: human_reference_atlas synonym: "CFU-GEMM" RELATED OMO:0003000 [ISBN:0878932437] synonym: "CFU-S" RELATED OMO:0003000 [ISBN:0878932437] @@ -316,6 +321,7 @@ id: CL:0000050 name: megakaryocyte-erythroid progenitor cell def: "A progenitor cell committed to the megakaryocyte and erythroid lineages." [GOC:add, GOC:dsd, GOC:tfm, http://en.wikipedia.org/wiki/Megakaryocyte-erythroid_progenitor_cell, MESH:D055015, PMID:16647566] comment: MEPs are reportedly CD19-negative, CD34-negative, CD45RA-negative, CD110-positive, CD117-positive, and SCA1-negative and reportedly express the transcription factors GATA-1 and NF-E2. +subset: cellxgene_subset subset: human_reference_atlas synonym: "CFU-EM" EXACT [] synonym: "CFU-MegE" EXACT [] @@ -341,6 +347,7 @@ id: CL:0000051 name: common lymphoid progenitor def: "A oligopotent progenitor cell committed to the lymphoid lineage." [GOC:add, GOC:dsd, GOC:tfm, PMID:10407577, PMID:16551251] comment: CLP are CD7-positive, CD10-positive, CD19-negative, CD34-positive, CD45RA-positive, CD79a-negative, CD127-positive, AA4.1-positive, RAG-negative, Sca-1-low, sIgM-negative, sIgD-negative, TdT-negative, Vpre-B-negative, and pre-BCR-negative. Expression of transcription factors include E2A-positive, EBF-positive, Ikaros-negative, PU.1-negative, and Pax5-negative. +subset: cellxgene_subset subset: human_reference_atlas synonym: "CLP" RELATED OMO:0003000 [] synonym: "committed lymphopoietic stem cell" RELATED [] @@ -372,6 +379,7 @@ id: CL:0000055 name: non-terminally differentiated cell def: "A precursor cell with a limited number of potential fates." [SANBI:mhl] comment: define using PATO mulit-potent or oligopotent? +subset: cellxgene_subset synonym: "blast cell" EXACT [] xref: BTO:0000125 xref: FMA:84782 @@ -393,6 +401,7 @@ id: CL:0000057 name: fibroblast def: "A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped." [http://en.wikipedia.org/wiki/Fibroblast, ISBN:0517223651, MESH:D005347] comment: These cells may be vimentin-positive, fibronectin-positive, fsp1-positive, MMP-1-positive, collagen I-positive, collagen III-positive, and alpha-SMA-negative. +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas xref: BTO:0000452 @@ -408,6 +417,7 @@ relationship: present_in_taxon NCBITaxon:9606 id: CL:0000066 name: epithelial cell def: "A cell that is usually found in a two-dimensional sheet with a free surface. The cell has a cytoskeleton that allows for tight cell to cell contact and for cell polarity where apical part is directed towards the lumen and the basal part to the basal lamina." [FB:ma, GOC:tfm, MESH:D004847] +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "epitheliocyte" EXACT [] @@ -427,6 +437,7 @@ property_value: depiction "https://www.swissbiopics.org/api/image/Epithelial_cel id: CL:0000071 name: blood vessel endothelial cell def: "An endothelial cell that lines the vasculature." [GOC:tfm] +subset: cellxgene_subset subset: human_reference_atlas synonym: "cuboidal endothelial cell of vascular tree" EXACT [] is_a: CL:0000076 {is_inferred="true"} ! squamous epithelial cell @@ -440,6 +451,7 @@ relationship: present_in_taxon NCBITaxon:9606 [Term] id: CL:0000076 name: squamous epithelial cell +subset: cellxgene_subset xref: CALOHA:TS-1249 is_a: CL:0000066 ! epithelial cell @@ -456,6 +468,7 @@ relationship: part_of UBERON:0000179 ! haemolymphatic fluid id: CL:0000081 name: blood cell def: "A cell found predominately in the blood." [GOC:add, GOC:tfm] +subset: cellxgene_subset subset: general_cell_types_upper_slim xref: FMA:62844 xref: MESH:D001773 @@ -468,6 +481,7 @@ relationship: capable_of GO:0008015 ! blood circulation id: CL:0000084 name: T cell def: "A type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex." [GOC:add, GOC:tfm, ISBN:0781735149] +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "immature T cell" RELATED [] @@ -493,6 +507,7 @@ id: CL:0000092 name: osteoclast def: "A specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue, which typically differentiates from monocytes. This cell has the following markers: tartrate-resistant acid phosphatase type 5-positive, PU.1-positive, c-fos-positive, nuclear factor NF-kappa-B p100 subunit-positive, tumor necrosis factor receptor superfamily member 11A-positive and macrophage colony-stimulating factor 1 receptor-positive." [GO_REF:0000031, GOC:add, GOC:tfm, ISBN:0781735149, PMID:10428500, PMID:15055519, PMID:17380158] comment: Morphology: Highly vesicular; markers: Surface: RANK, cFMS (MCSF receptor); Secreted: cathepsin K and TRAP (tartate resistant acid phosphatase); transcription factors: PU.1, cFOS, MITF, NFkB (p52); role or process: tissue remodelling: bone resorption; lineage: hematopoietic, myeloid. +subset: cellxgene_subset synonym: "chondroclast" RELATED [] xref: BTO:0000968 xref: CALOHA:TS-0721 @@ -526,6 +541,7 @@ relationship: RO:0002104 PR:000002062 ! has plasma membrane part macrophage colo id: CL:0000094 name: granulocyte def: "A leukocyte with abundant granules in the cytoplasm." [GOC:amm, GOC:tfm, http://en.wikipedia.org/wiki/Granulocyte, MESH:D006098] +subset: cellxgene_subset subset: human_reference_atlas synonym: "granular leucocyte" EXACT [] synonym: "granular leukocyte" EXACT [] @@ -563,6 +579,7 @@ name: mast cell def: "A cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation. Progenitors leave bone marrow and mature in connective and mucosal tissue. Mature mast cells are found in all tissues, except the bloodstream. Their phenotype is CD117-high, CD123-negative, CD193-positive, CD200R3-positive, and FceRI-high. Stem-cell factor (KIT-ligand; SCF) is the main controlling signal of their survival and development." [GOC:add, GOC:dsd, GOC:tfm, ISBN:068340007X, MESH:D008407, PMCID:PMC1312421, PMCID:PMC2855166, PMID:15153310, PMID:16455980, PMID:19671378, PMID:212366338, PMID:9354811] comment: Mast cells are generally integrin beta-7-negative and positive for TLR2, TLR3, TLR4, TLR5, TLR7, TLR9, C3aR, C5aR, CR3, CR4, VEGF, FGF2, and renin. They can express MHC Class I and II on their surface. Activated murine mast cells (IgE+Antigen) were capable of expressing the following co-stimulatory molecules: CD95 (Fas), CD120b, CD137 (4-1BB), CD153 (CD30L), CD154 (CD40L), GITR, ICOSL, OX40L, PD-L1, and PD-L2. Note that there was some mouse strain variation. Mast cells have also been demonstrated to produce bFGF, CCL2, CCL4, CCL5, CCL11, CCL20, CXCL2, CXCL8, CXCL10, GM-CSF, IFN-gamma, IL-1, IL-2, IL-3, IL-8, IL-10, IL-11, IL-12, IL-13, IL-16, IL-25, IL-18, MIP-1, prostaglandin D2, SCF, TGF-beta, TNF-alpha, TSLP, VEGF, and XCL1. They express the transcription factors Transcription factors AP-1, GATA1, MITF, Notch2, PIAS3, PU.1, and STAT5. subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "histaminocyte" EXACT [] synonym: "labrocyte" EXACT [ISBN:0721601464] @@ -606,6 +623,7 @@ relationship: RO:0015015 PR:000007431 ! has high plasma membrane amount high aff id: CL:0000113 name: mononuclear phagocyte def: "A vertebrate phagocyte with a single nucleus." [GOC:add, GOC:tfm, ISBN:0781735149] +subset: cellxgene_subset subset: human_reference_atlas xref: BTO:0001433 is_a: CL:0000518 {is_inferred="true"} ! phagocyte (sensu Vertebrata) @@ -619,6 +637,7 @@ id: CL:0000115 name: endothelial cell def: "An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal. In mammals, endothelial cell has vimentin filaments and is derived from the mesoderm." [GOC:tfm, http://en.wikipedia.org/wiki/Endothelial_cell, https://sourceforge.net/tracker/?func=detail&atid=440764&aid=3364936&group_id=36855, MESH:D042783, PMID:21275341] comment: From FMA: 9.07.2001: Endothelial cell has always been classified as a kind of epithelial cell, specifically a squamous cell but that is not true. First, endothelial cell can either be squamous or cuboidal (e.g. high-endothelial cell) and secondly, it has different embryological derivation (mesodermal) than a true epithelial cell (ectodermal and endodermal). The basis for present classification is the fact that it comprises the outermost layer or lining of anatomical structures (location-based) but a better structural basis for the differentia is the cytoskeleton of the cell. Endothelial cell has vimentin filaments while an epithelial cell has keratin filaments. [Onard]. +subset: cellxgene_subset subset: human_reference_atlas synonym: "endotheliocyte" EXACT [] xref: BTO:0001176 @@ -640,6 +659,7 @@ id: CL:0000134 name: mesenchymal stem cell def: "A connective tissue cell that normally gives rise to other cells that are organized as three-dimensional masses. In humans, this cell type is CD73-positive, CD90-positive, CD105-positive, CD45-negative, CD34-negative, and MHCII-negative. They may further differentiate into osteoblasts, adipocytes, myocytes, neurons, or chondroblasts in vitro. Originally described as residing in the bone marrow, this cell type is now known to reside in many, if not all, adult organs." [FB:ma, GOC:dsd, http://en.wikipedia.org/wiki/Mesenchymal_stem_cell, http://www.copewithcytokines.de/cope.cgi?key=mesenchymal%20stem%20cells, PMCID:PMC2613570, PMID:10102814, PMID:16923606, PMID:17986482, PMID:19960544] comment: Many but not all mesenchymal cells derive from the mesoderm. MSCs are reportedly CD3-negative, CD4-negative, CD5-negative, CD8-negative, CD11a-negative, CD11b-negative, CD14-negative, CD19-negative, CD29-positive, CD31-negative, CD34-negative, CD38-negative, CD40-negative, CD44-positive, CD45-negative, CD49-positive, CD54-positive, CD66b-negative, CD79a-negative, CD80-negative, CD102-positive, CD106-positive, CD117-positive, CD121a-positive, CD121b-positive, CD123-positive, CD124-positive, CD133-negative, CD146-positive, CD166-positive, CD271-positive, B220-negative, Gr1-negative, MHCI-positive, MHCII-negative, SSEA4-negative, sca1-positive, Ter119-negative, and glycophorin A-negative. Cultured MSCs are capable of producing stem cell factor, IL7, IL8, IL11, TGF-beta, cofilin, galectin-1, laminin-receptor 1, cyclophilin A, and MMP-2. +subset: cellxgene_subset synonym: "BMSC" RELATED OMO:0003000 [] synonym: "bone marrow stromal cells" NARROW [] synonym: "CFU-F" RELATED OMO:0003000 [] @@ -665,6 +685,7 @@ name: professional antigen presenting cell def: "A cell capable of processing and presenting lipid and protein antigens to T cells in order to initiate an immune response." [GOC:add, ISBN:0781735149] comment: Note change of name; nearly all somatic cells can present antigens to T cells via MHC Class I complexes leading to effector responses, but professional antigen presenting cells constitutively express MHC Class II as well as costimulatory molecules, and thus can initiate immune responses via T cells. subset: blood_and_immune_upper_slim +subset: cellxgene_subset synonym: "APC" RELATED OMO:0003000 [] is_a: CL:0000738 ! leukocyte intersection_of: CL:0000738 ! leukocyte @@ -675,6 +696,7 @@ relationship: capable_of GO:0002504 ! antigen processing and presentation of pep id: CL:0000151 name: secretory cell def: "A cell that specializes in controlled release of one or more substances." [GOC:tfm, ISBN:0721662544] +subset: cellxgene_subset xref: BTO:0003659 xref: FMA:86916 is_a: CL:0000000 ! cell @@ -686,12 +708,14 @@ relationship: capable_of GO:0032940 ! secretion by cell id: CL:0000183 name: contractile cell def: "A cell whose primary function is to shorten." [FB:ma] +subset: cellxgene_subset is_a: CL:0000000 ! cell [Term] id: CL:0000187 name: muscle cell def: "A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns." [MESH:D032342] +subset: cellxgene_subset synonym: "muscle fiber" EXACT [] synonym: "myocyte" EXACT [] xref: BTO:0000888 @@ -746,6 +770,7 @@ relationship: part_of UBERON:0000924 ! ectoderm id: CL:0000222 name: mesodermal cell def: "A cell of the middle germ layer of the embryo." [MESH:D008648] +subset: cellxgene_subset synonym: "mesoblast" EXACT [] synonym: "mesoderm cell" EXACT [] xref: FMA:72554 @@ -801,6 +826,7 @@ id: CL:0000232 name: erythrocyte def: "A red blood cell. In mammals, mature erythrocytes are biconcave disks containing hemoglobin whose function is to transport oxygen." [GOC:tfm, MESH:D004912] subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "RBC" EXACT [] synonym: "red blood cell" EXACT [] @@ -828,6 +854,7 @@ name: platelet def: "A non-nucleated disk-shaped cell formed by extrusion from megakaryocytes, found in the blood of all mammals, and mainly involved in blood coagulation." [GOC:add, GOC:dsd, GOC:tfm, http://en.wikipedia.org/wiki/Platelet, MESH:D001792, PMID:11110672, PMID:16987572, PMID:17204662, PMID:17479180, PMID:20414831] comment: Platelets are reportedly CCR1-positive, CCR2-negative, CCR3-positive, CCR4-positive, CCR5-negative, CCR6-negative, CCR7-negative, CCR8-negative, CCR9-negative, CCR10-negative, CD16-positive, CD23-positive, CD32-positive, CD40-positive, CD41-positive CD42-positive, CD61-positive, CD62P-positive, CD64-positive, CD89-positive, CD102-positive, CD147-positive (activated platelets), CD154-positive (activated platelets), CD162-positive, CD209, CD282-positive, CD284-positive, CD289-positive, CD181-negative, CD182-negative, CD183-negative, CD184-positive, CLEC2-positive, GPVI-positive, JAMC-positive, PAR1-positive, PAR2-negative, PAR3-positive, PAR4-positive, TSP1-positive, and TXA2R-positive. Platelets can reportedly produce CCL2, CCL3, CCL5, CCL7, CCL17, CD40L, CXCL1, CXCL4, CXCL4L1, CXCL5, CXCL7, CXCL8, CXCL12, EGF, factor V, factor VII, factor XI, factor XIII, bFGF, histamine, IGF-1, IL-1beta, PAI-1, PDGF, plasminogen, protein S, serotonin, TGF-beta, TFPI, VEGF, and vWF. subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "anucleate thrombocyte" EXACT [] synonym: "blood platelet" EXACT [] @@ -848,6 +875,7 @@ relationship: present_in_taxon NCBITaxon:9606 id: CL:0000234 name: phagocyte def: "Any cell capable of ingesting particulate matter via phagocytosis." [GOC:add, ISBN:0721601464] +subset: cellxgene_subset xref: BTO:0001044 xref: FMA:83806 xref: MESH:D010586 @@ -864,6 +892,7 @@ name: macrophage def: "A mononuclear phagocyte present in variety of tissues, typically differentiated from monocytes, capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells." [GO_REF:0000031, GOC:add, GOC:tfm, PMID:16213494, PMID:1919437] comment: Morphology: Diameter 30_M-80 _M, abundant cytoplasm, low N/C ratio, eccentric nucleus. Irregular shape with pseudopods, highly adhesive. Contain vacuoles and phagosomes, may contain azurophilic granules; markers: Mouse & Human: CD68, in most cases CD11b. Mouse: in most cases F4/80+; role or process: immune, antigen presentation, & tissue remodelling; lineage: hematopoietic, myeloid. subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "histiocyte" EXACT [] @@ -888,6 +917,7 @@ id: CL:0000236 name: B cell def: "A lymphocyte of B lineage that is capable of B cell mediated immunity." [GO_REF:0000031, GOC:add, GOC:tfm, ISBN:0781735149] subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "B lymphocyte" EXACT [] @@ -907,6 +937,7 @@ relationship: present_in_taxon NCBITaxon:9606 [Term] id: CL:0000255 name: eukaryotic cell +subset: cellxgene_subset xref: MESH:D005057 is_a: CL:0000000 ! cell intersection_of: CL:0000000 ! cell @@ -981,6 +1012,7 @@ is_a: CL:0000211 ! electrically active cell id: CL:0000451 name: dendritic cell def: "A cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation. These cells are lineage negative (CD3-negative, CD19-negative, CD34-negative, and CD56-negative)." [GOC:add, ISBN:0781735149] +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "interdigitating cell" RELATED [] @@ -1050,6 +1082,7 @@ id: CL:0000540 name: neuron def: "The basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system." [http://en.wikipedia.org/wiki/Neuron, MESH:D009474] comment: These cells are also reportedly CD4-negative and CD200-positive. They are also capable of producing CD40L and IFN-gamma. +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "nerve cell" EXACT [] @@ -1071,6 +1104,7 @@ id: CL:0000542 name: lymphocyte def: "A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin." [GOC:add, ISBN:0683073696, ISBN:0781735149] comment: Editors note: consider adding taxon constraint to vertebrata (PMID:18025161) +subset: cellxgene_subset subset: human_reference_atlas xref: BTO:0000775 xref: CALOHA:TS-0583 @@ -1081,13 +1115,13 @@ is_a: CL:0000842 ! mononuclear cell is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000738 ! leukocyte intersection_of: bearer_of PATO:0001407 ! mononucleate +intersection_of: bearer_of PATO:0040072 ! high nuclear/cytoplasmic ratio intersection_of: has_part CL:0017500 ! neutrophillic cytoplasm -intersection_of: has_part CL:0017505 ! increased nucleus size intersection_of: has_part GO:0000792 ! heterochromatin disjoint_from: CL:0000766 ! myeloid leukocyte +relationship: bearer_of PATO:0040072 ! high nuclear/cytoplasmic ratio relationship: develops_from CL:0000051 ! common lymphoid progenitor relationship: has_part CL:0017500 ! neutrophillic cytoplasm -relationship: has_part CL:0017505 ! increased nucleus size relationship: has_part GO:0000792 ! heterochromatin relationship: present_in_taxon NCBITaxon:9606 @@ -1096,6 +1130,7 @@ id: CL:0000547 name: proerythroblast def: "An immature, nucleated erythrocyte occupying the stage of erythropoeisis that follows formation of erythroid progenitor cells. This cell is CD71-positive, has both a nucleus and a nucleolus, and lacks hematopoeitic lineage markers." [ISBN:0721601464, PMID:1638021] subset: blood_and_immune_upper_slim +subset: cellxgene_subset synonym: "pronormoblast" RELATED [] synonym: "rubriblast" EXACT [ISBN:0721601464] xref: FMA:83518 @@ -1104,6 +1139,7 @@ is_a: CL:0002242 ! nucleate cell is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000764 ! erythroid lineage cell intersection_of: bearer_of PATO:0002505 ! nucleated +intersection_of: bearer_of PATO:0040072 ! high nuclear/cytoplasmic ratio intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M @@ -1116,9 +1152,9 @@ intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell sur intersection_of: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule intersection_of: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G intersection_of: has_part CL:0017503 ! basophilic cytoplasm -intersection_of: has_part CL:0017505 ! increased nucleus size intersection_of: has_part GO:0005730 ! nucleolus intersection_of: RO:0002104 PR:000001945 ! has plasma membrane part transferrin receptor protein 1 +relationship: bearer_of PATO:0040072 ! high nuclear/cytoplasmic ratio relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M @@ -1132,7 +1168,6 @@ relationship: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule relationship: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G relationship: develops_from CL:0000038 ! erythroid progenitor cell relationship: has_part CL:0017503 ! basophilic cytoplasm -relationship: has_part CL:0017505 ! increased nucleus size relationship: has_part GO:0005730 ! nucleolus relationship: RO:0002104 PR:000001945 ! has plasma membrane part transferrin receptor protein 1 @@ -1200,6 +1235,7 @@ id: CL:0000553 name: megakaryocyte progenitor cell def: "The earliest cytologically identifiable precursor in the thrombocytic series. This cell is capable of endomitosis and lacks expression of hematopoieitic lineage markers (lin-negative)." [GOC:dsd, GOC:tfm, ISBN:0721601464] comment: Lineage negative is described here as CD2-negative, CD3-negative, CD4-negative, CD5-negative, CD8a-negative, CD14-negative, CD19-negative, CD20-negative, CD56-negative, Ly6g-negative, and Ter119-negative. +subset: cellxgene_subset subset: human_reference_atlas synonym: "CFU-Meg" EXACT [PMID:11722431, PMID:12482498] synonym: "colony-forming unit-megakaryocyte" EXACT [] @@ -1255,6 +1291,7 @@ name: megakaryocyte def: "A large hematopoietic cell (50 to 100 micron) with a lobated nucleus. Once mature, this cell undergoes multiple rounds of endomitosis and cytoplasmic restructuring to allow platelet formation and release." [http://en.wikipedia.org/wiki/Megakaryocyte, ISBN:0721601464, MESH:D008533, PMID:31043076] comment: Megakaryocytes are reportedly CD181-positive and CD182-positive. subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "megacaryocyte" EXACT [] synonym: "megalocaryocyte" EXACT [] @@ -1273,6 +1310,7 @@ id: CL:0000557 name: granulocyte monocyte progenitor cell def: "A hematopoietic progenitor cell that is committed to the granulocyte and monocyte lineages. These cells are CD123-positive, and do not express Gata1 or Gata2 but do express C/EBPa, and Pu.1." [GO_REF:0000031, GOC:amm, GOC:dsd, GOC:tfm, http://en.wikipedia.org/wiki/CFU-GM, http://www.copewithcytokines.de, ISBN:0721601464, MESH:D055014, PMCID:PMC2213186, PMCID:PMC548021, PMID:16551251, PMID:16647566] comment: Originally described in the dendritic cell ontology (DC_CL:0000042)(PMID:19243617). GMPs are reportedly CD16-positive, CD32-positive, CD34-positive, CD38-positive, CD45RA-positive, CD110-negative, CD117-positive, CD123-positive, and SCA1-negative. +subset: cellxgene_subset subset: human_reference_atlas synonym: "CFU-C , Colony forming unit in culture" BROAD [http://www.copewithcytokines.de] synonym: "CFU-GM" RELATED OMO:0003000 [ISBN:0721601464, PMCID:PMC2213186, PMCID:PMC548021] @@ -1309,6 +1347,7 @@ id: CL:0000558 name: reticulocyte def: "An immature erythrocyte that changes the protein composition of its plasma membrane by exosome formation and extrusion. The types of protein removed differ between species though removal of the transferrin receptor is apparent in mammals and birds." [GOC:add, GOC:tfm, PMID:15946868, PMID:2037622] subset: blood_and_immune_upper_slim +subset: cellxgene_subset xref: BTO:0001173 xref: CALOHA:TS-0864 xref: MESH:D012156 @@ -1348,6 +1387,7 @@ id: CL:0000559 name: promonocyte def: "A precursor in the monocytic series, being a cell intermediate in development between the monoblast and monocyte. This cell is CD11b-positive and has fine azurophil granules." [GOC:tfm, ISBN:0721601464] comment: Morphology: Mononuclear cell, diameter 14-18 _M, fine azurophilic granules; markers: CD11b (shared with many other myeloid cells); location: Adult: bone marrow; Fetal: Liver, Yolk Sac; role or process: hematopoiesis, monocyte development; lineage: hematopoietic, myeloid. +subset: cellxgene_subset subset: human_reference_atlas xref: BTO:0004657 xref: FMA:83551 @@ -1388,6 +1428,7 @@ name: monocyte def: "Myeloid mononuclear recirculating leukocyte that can act as a precursor of tissue macrophages, osteoclasts and some populations of tissue dendritic cells." [GO_REF:0000031, MESH:D009000] comment: Morphology: Mononuclear cell, diameter, 14 to 20 _M, N/C ratio 2:1-1:1. Nucleus may appear in variety of shapes: round, kidney, lobulated, or convoluted. Fine azurophilic granules present; markers: CD11b (shared with other myeloid cells), human: CD14, mouse: F4/80-mid,GR1-low; location: Blood, but can be recruited into tissues; role or process: immune & tissue remodelling; lineage: hematopoietic, myeloid. subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas xref: BTO:0000876 @@ -1435,11 +1476,12 @@ relationship: participates_in GO:0002544 ! chronic inflammatory response id: CL:0000680 name: muscle precursor cell def: "A non-terminally differentiated cell that is capable of developing into a muscle cell." [GOC:add] +subset: cellxgene_subset is_a: CL:0000055 ! non-terminally differentiated cell intersection_of: CL:0011115 ! precursor cell -intersection_of: RO:0002203 CL:0000187 ! develops into muscle cell +intersection_of: develops_into CL:0000187 ! muscle cell relationship: develops_from CL:0000222 ! mesodermal cell -relationship: RO:0002203 CL:0000187 ! develops into muscle cell +relationship: develops_into CL:0000187 ! muscle cell [Term] id: CL:0000723 @@ -1456,6 +1498,7 @@ relationship: capable_of GO:0048103 ! somatic stem cell division id: CL:0000738 name: leukocyte def: "An achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue." [GOC:add, GOC:tfm, ISBN:978-0-323-05290-0] +subset: cellxgene_subset subset: human_reference_atlas synonym: "immune cell" RELATED [] synonym: "leucocyte" EXACT [] @@ -1496,6 +1539,7 @@ relationship: develops_from CL:0000828 ! thromboblast id: CL:0000763 name: myeloid cell def: "A cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage." [GOC:add] +subset: cellxgene_subset xref: BTO:0001441 xref: CALOHA:TS-0647 xref: MESH:D022423 @@ -1509,6 +1553,7 @@ id: CL:0000764 name: erythroid lineage cell def: "A immature or mature cell in the lineage leading to and including erythrocytes." [GOC:add, GOC:tfm] comment: Note that in FMA erythropoietic cells are types of nucleated erythrocytes and thus don't include erythrocytes. +subset: cellxgene_subset subset: human_reference_atlas synonym: "erythropoietic cell" EXACT [] xref: CALOHA:TS-0290 @@ -1522,6 +1567,7 @@ id: CL:0000765 name: erythroblast def: "A nucleated precursor of an erythrocyte that lacks hematopoietic lineage markers." [GOC:add, ISBN:0721601464, PMID:18174176] subset: blood_and_immune_upper_slim +subset: cellxgene_subset synonym: "normoblast" EXACT [] xref: BTO:0001571 xref: CALOHA:TS-0289 @@ -1564,6 +1610,7 @@ relationship: has_part GO:0005634 ! nucleus id: CL:0000766 name: myeloid leukocyte def: "A cell of the monocyte, granulocyte, or mast cell lineage." [GOC:add] +subset: cellxgene_subset is_a: CL:0000738 {is_inferred="true"} ! leukocyte is_a: CL:0000763 ! myeloid cell intersection_of: CL:0000738 ! leukocyte @@ -1575,6 +1622,7 @@ name: basophil def: "Any of the immature or mature forms of a granular leukocyte that in its mature form has an irregularly shaped, pale-staining nucleus that is partially constricted into two lobes, and with cytoplasm that contains coarse, bluish-black granules of variable size. Basophils contain vasoactive amines such as histamine and serotonin, which are released on appropriate stimulation. A basophil is CD123-positive, CD193-positive, CD203c-positive, and FceRIa-positive." [GOC:add, GOC:amm, GOC:dsd, GOC:tfm, ISBN:0721601464, MESH:D001491, PMCID:PMC2626675, PMID:11927641, PMID:19741522, PMID:21236338, PMID:9933081] comment: Matures in the bone marrow and account for <1% of leukocytes in the peripheral blood, spleen, and bone marrow. Basophils are described as being CD11a-positive, CD11b-positive, CD13-positive, CD15-positive, CD18-positive, CD21-positive, CD25-positive, CD29-positive, CD35-positive, CD40-positive, CD40L-positive, CD44-positive, CD45R-negative, CD46-positive, CD49a-positive, CD49b-positive, CD49d-positive, CD55-positive, CD59-positive, CD62L-positive, CD63-positive, CD69-positive, CD90-negative, CD116-positive, CD117-negative, CD124-positive, CD125-positive, CD131-positive, CD161-positive, CD184-positive, CD191-positive, CD192-positive, CD197-positive, CD200R3-positive, CD218-positive, CD282-positive, CD284-positive, CD289-positive, CD290-positive, CD294-positive, natural killer cell receptor 2B4-positive, smad1-positive, CD3-negative, CD4-negative, CD7-negative, CD8-negative, CD14-negative, CD15-negative, CD16-negative, CD19-negative, CD20-negative, CD34-negative, CD36-negative, CD45R-negative, CD56-negative, CD57-negative, CD235a-negative, and GR1-negative. Transcription factors- GATA1-positive, PU.1-positive. subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "basophilic leucocyte" EXACT [] synonym: "basophilic leukocyte" EXACT [] @@ -1603,6 +1651,7 @@ name: eosinophil def: "Any of the immature or mature forms of a granular leukocyte with a nucleus that usually has two lobes connected by one or more slender threads of chromatin, and cytoplasm containing coarse, round granules that are uniform in size and which can be stained by the dye eosin. Eosinophils are CD9-positive, CD191-positive, and CD193-positive." [GOC:add, GOC:amm, GOC:dsd, GOC:tfm, ISBN:0721601464, PMCID:PMC2626675, PMID:10914487, PMID:1662676] comment: Eosinophils are also CD14-negative, CD32-positive, CD44-positive, CD48-positive, CD69-positive, CD192-negative, MBP1-positive, MBP2-positive, TLR2-negative, TLR4-negative, and lineage-negative (B220, CD2, CD14, CD19, CD56, CD71, CD117, CD123, CD235a (glycophorin A), and TER119). The cytokines IL-3, IL-5, and GM-CSF are involved in their development and differentiation. Usually considered CD16-negative, CD16 is observed on eosinophilic metamyelocyte. subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "eosinocyte" EXACT [] synonym: "eosinophilic granulocyte" EXACT [] @@ -1633,6 +1682,7 @@ id: CL:0000775 name: neutrophil def: "Any of the immature or mature forms of a granular leukocyte that in its mature form has a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes." [GOC:add, GOC:amm, GOC:tfm, ISBN:0721601464] subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "neutrocyte" EXACT [] synonym: "neutrophil leucocyte" EXACT [] @@ -1663,6 +1713,7 @@ id: CL:0000782 name: myeloid dendritic cell def: "A dendritic cell of the myeloid lineage." [GOC:add, PMID:10449155, PMID:17332250, PMID:9521319] comment: These cells are CD1a-negative, CD1b-positive, CD11a-positive, CD11c-positive, CD13-positive, CD14-negative, CD20-negative, CD21-negative, CD33-positive, CD40-negative, CD50-positive, CD54-positive, CD58-positive, CD68-negative, CD80-negative, CD83-negative, CD85j-positive, CD86-positive, CD89-negative, CD95-positive, CD120a-negative, CD120b-positive, CD123-negative, CD178-negative, CD206-negative, CD207-negative, CD209-negative, and TNF-alpha-negative. Upon TLR stimulation, they are capable of producing high levels of TNF-alpha, IL-6, CXCL8 (IL-8). +subset: cellxgene_subset synonym: "CD11c+CD123- DC" EXACT [] synonym: "interdigitating cell" BROAD [] synonym: "mDC" EXACT [] @@ -1681,6 +1732,7 @@ id: CL:0000784 name: plasmacytoid dendritic cell def: "A dendritic cell type of distinct morphology, localization, and surface marker expression (CD123-positive) from other dendritic cell types and associated with early stage immune responses, particularly the release of physiologically abundant amounts of type I interferons in response to infection." [GOC:add, GOC:dsd, PMCID:PMC2118448, PMCID:PMC538703, PMID:15549123, PMID:17332250, PMID:17850486, PMID:20304825] subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "DC2" EXACT [] synonym: "interferon-producing cell" EXACT [] @@ -1703,6 +1755,7 @@ id: CL:0000785 name: mature B cell def: "A B cell that is mature, having left the bone marrow. Initially, these cells are IgM-positive and IgD-positive, and they can be activated by antigen." [GOC:add, GOC:dsd, ISBN:0781735149] comment: Mature B cells are also reportedly CD10-negative, CD19-positive, CD22-positive, CD34-negative, CD48-positive, CD79a-positive, CD84-positive, CD127-negative, CD352-positive, RAG-negative, TdT-negative, Vpre-B-negative, and pre-BCR-negative. Transcription factors expressed: Pax5-positive. +subset: cellxgene_subset synonym: "mature B lymphocyte" EXACT [] synonym: "mature B-cell" EXACT [] synonym: "mature B-lymphocyte" EXACT [] @@ -1725,6 +1778,7 @@ name: plasma cell def: "A terminally differentiated, post-mitotic, antibody secreting cell of the B cell lineage with the phenotype CD138-positive, surface immunonoglobulin-negative, and MHC Class II-negative. Plasma cells are oval or round with extensive rough endoplasmic reticulum, a well-developed Golgi apparatus, and a round nucleus having a characteristic cartwheel heterochromatin pattern and are devoted to producing large amounts of immunoglobulin." [GO_REF:0000031, GOC:add, GOC:dsd, http://en.wikipedia.org/wiki/Plasma_cell, ISBN:0721601464, ISBN:0781735149, PMID:19447676, PMID:20081059, PMID:20839338, PMID:20951740] comment: Plasma cells develop in the spleen and migrate to the bone marrow. Plasma cells are also reportedly CD5-negative, CD10-negative, CD19-positive, CD20-negative, CD21-negative, CD22-negative, CD23-negative, CD24-negative, CD25-negative, CD27-positive, CD34-negative, CD38-positive, CD40-positive, CD43-positive, CD45-positive, CD48-positive, CD53-low, CD80-negative, CD81-positive, CD86-positive, CD95-positive, CD196-negative, CD229-positive, CD270-positive, CD352-positive, CD361-positive, and IgD-negative. Transcription factors: BLIMP1-positive, IRF4-positive, PAX5-negative, SpiB-negative, Ets1-negative, and XBP1-positive. subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "effector B cell" RELATED [] synonym: "effector B-cell" RELATED [] @@ -1757,6 +1811,7 @@ id: CL:0000789 name: alpha-beta T cell def: "A T cell that expresses an alpha-beta T cell receptor complex." [GOC:add, GOC:tfm, ISBN:0781735149] subset: blood_and_immune_upper_slim +subset: cellxgene_subset synonym: "alpha-beta T lymphocyte" EXACT [] synonym: "alpha-beta T-cell" EXACT [] synonym: "alpha-beta T-lymphocyte" EXACT [] @@ -1772,6 +1827,7 @@ name: gamma-delta T cell def: "A T cell that expresses a gamma-delta T cell receptor complex." [GOC:add, GOC:tfm, ISBN:0781735149] comment: Note that gamma-delta T cells have both thymic and extrathymic differentiation pathways. subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "gamma-delta T lymphocyte" EXACT [] synonym: "gamma-delta T-cell" EXACT [] @@ -1790,6 +1846,7 @@ name: immature B cell def: "An immature B cell is a B cell that has the phenotype surface IgM-positive and surface IgD-negative, and have not undergone class immunoglobulin class switching or peripheral encounter with antigen and activation." [GO_REF:0000031, GOC:add, GOC:dsd, GOC:rhs, GOC:tfm, ISBN:0781735149, PMID:20081059, PMID:20839338] comment: Immature B cells are also reportedly CD5-positive, CD10-positive, CD19-positive, CD20-positive, CD21-positive, CD22-positive, CD24-positive, CD25-negative, CD27-negative, CD34-negative, CD38-positive, CD40-positive, CD43-negative, CD45-positive, CD48-positive, CD53-positive, CD79a-positive, CD80-negative, CD81-positive, CD86-negative, CD95-negative, CD127-negative, CD138-negative, CD185-positive, CD196-positive, MHCII/HLA-DR-positive, RAG-positive, TdT-negative, Vpre-B-negative, and preBCR-negative. Transcription factors expressed: Pax5-positive. subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "immature B lymphocyte" EXACT [] synonym: "immature B-cell" EXACT [] @@ -1812,6 +1869,7 @@ relationship: RO:0002104 PR:000001289 ! has plasma membrane part membrane-spanni id: CL:0000817 name: precursor B cell def: "A precursor B cell is a B cell with the phenotype CD10-positive." [GO_REF:0000031, GOC:rhs, GOC:tfm] +subset: cellxgene_subset subset: human_reference_atlas synonym: "pre-B cell" RELATED [] xref: BTO:0001133 @@ -1830,6 +1888,7 @@ id: CL:0000818 name: transitional stage B cell def: "An immature B cell of an intermediate stage between the pre-B cell stage and the mature naive stage with the phenotype surface IgM-positive and CD19-positive, and are subject to the process of B cell selection. A transitional B cell migrates from the bone marrow into the peripheral circulation, and then to the spleen." [GO_REF:0000031, GOC:add, ISBN:0781735149, PMID:12810111, PMID:22343568] comment: This cell type is compatible with the HIPC Lyoplate markers for 'transitional B cell'. +subset: cellxgene_subset subset: human_reference_atlas synonym: "T1 B cell" NARROW [] synonym: "T2 B cell" NARROW [] @@ -1858,6 +1917,7 @@ id: CL:0000826 name: pro-B cell def: "A progenitor cell of the B cell lineage, with some lineage specific activity such as early stages of recombination of B cell receptor genes, but not yet fully committed to the B cell lineage until the expression of PAX5 occurs." [GOC:add, GOC:dsd, ISBN:0781735149, PMID:12633665, PMID:16551251, PMID:18432934] comment: Human pro-B cells are reportedly CD10-positive, CD22-positive, CD34-positive, CD38-positive, CD45-low, CD48-positive, CD79a-positive, CD127-positive, CD184-positive, RAG-positive, TdT-positive, Vpre-B-positive, pre-BCR-negative, IgD-negative, and IgM-negative. Transcription factors expressed: Pax5-positive, EBF-positive, E2A-negative, Ikaros-negative, and PU.1-negative. +subset: cellxgene_subset subset: human_reference_atlas synonym: "pre-B cell (Philadelphia nomenclature)" RELATED [PMID:11244048] synonym: "pre-pro B cell" BROAD [PMID:17582343] @@ -1885,6 +1945,7 @@ relationship: present_in_taxon NCBITaxon:9606 id: CL:0000827 name: pro-T cell def: "A lymphoid progenitor cell of the T cell lineage, with some lineage specific marker expression, but not yet fully committed to the T cell lineage." [GOC:add, ISBN:0781735149] +subset: cellxgene_subset synonym: "DN1 cell" NARROW [] synonym: "DN1 thymocyte" NARROW [] synonym: "pro-T lymphocyte" EXACT [] @@ -1979,6 +2040,7 @@ name: hematopoietic multipotent progenitor cell def: "A hematopoietic multipotent progenitor cell is multipotent, but not capable of long-term self-renewal. These cells are characterized as lacking lineage cell surface markers and being CD34-positive in both mice and humans." [GOC:add, GOC:tfm, PMID:19022770] comment: Markers differ between mouse and human. subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "hemopoietic progenitor cell" EXACT [] synonym: "MPP" EXACT [] @@ -2026,6 +2088,7 @@ id: CL:0000838 name: lymphoid lineage restricted progenitor cell def: "A progenitor cell restricted to the lymphoid lineage." [GOC:add, GOC:tfm] comment: Note that this is a class of cell types, not an identified single cell type. +subset: cellxgene_subset synonym: "lymphoid progenitor cell" BROAD [] xref: BTO:0004731 xref: CALOHA:TS-2025 @@ -2042,6 +2105,7 @@ id: CL:0000839 name: myeloid lineage restricted progenitor cell def: "A progenitor cell restricted to the myeloid lineage." [GOC:add, GOC:tfm, PMID:19022770] comment: Note that this is a class of cell types, not an identified single cell type. +subset: cellxgene_subset subset: human_reference_atlas synonym: "myeloid progenitor cell" BROAD [] xref: BTO:0004730 @@ -2059,6 +2123,7 @@ id: CL:0000842 name: mononuclear cell def: "A leukocyte with a single non-segmented nucleus in the mature form." [GOC:add] subset: blood_and_immune_upper_slim +subset: cellxgene_subset synonym: "mononuclear leukocyte" EXACT [] synonym: "peripheral blood mononuclear cell" NARROW [] xref: BTO:0000878 @@ -2111,6 +2176,7 @@ id: CL:0000954 name: small pre-B-II cell def: "A small pre-B-II cell is a pre-B-II cell that is Rag1-positive, Rag2-positive, pre-BCR-negative, and BCR-negative, is not proliferating, and carries a DNA rearrangement of one or more immunoglobulin light chain genes." [GO_REF:0000031, GOC:dsd, GOC:rhs, GOC:tfm, PMID:16551251, PMID:18432934, PMID:9785673] comment: Small pre-B-II cells are also reportedly CD10-positive, CD19-positive, CD34-negative, CD79a-positive, CD127-negative, TdT-negative, Vpre-B-negative, sIgM-negative, and sIgD-negative. Transcription factors: PU.1-positive, Ikaros-positive, E2A-positive, and PAX5-positive. +subset: cellxgene_subset synonym: "small pre-BII cell" EXACT [] is_a: CL:0000955 {is_inferred="true"} ! pre-B-II cell intersection_of: CL:0000955 ! pre-B-II cell @@ -2148,6 +2214,7 @@ id: CL:0000980 name: plasmablast def: "An activated mature (naive or memory) B cell that is secreting immunoglobulin, typified by being CD27-positive, CD38-positive, CD138-negative." [GO_REF:0000031, GOC:dsd, GOC:msz, GOC:tfm, PMCID:PMC2673126] comment: This cell type is compatible with the HIPC Lyoplate markers for 'plasmablast'. Plasmablasts are also reportedly CD48-positive, CD63-positive, CD229-positive, CD270-positive, CD319-positive, CD352-positive, CD361-positive, and IgD-negative. +subset: cellxgene_subset subset: human_reference_atlas synonym: "CD20-negative B cell" BROAD [] synonym: "CD27-positive, CD38-positive, CD20-negative B cell" EXACT [] @@ -2171,6 +2238,7 @@ relationship: RO:0015015 PR:000001963 ! has high plasma membrane amount CD27 mol id: CL:0000988 name: hematopoietic cell def: "A cell of a hematopoietic lineage." [GO_REF:0000031, GOC:add] +subset: cellxgene_subset synonym: "haematopoietic cell" EXACT [] synonym: "haemopoietic cell" EXACT [] synonym: "hemopoietic cell" EXACT [] @@ -2186,6 +2254,7 @@ name: conventional dendritic cell def: "Conventional dendritic cell is a dendritic cell that is CD11c-high." [GO_REF:0000031, GOC:amm, PMID:17850486] comment: Originally described in the dendritic cell ontology (DC_CL:0000003)(PMID:19243617) These cells are also CD20-negative, MHCII-positive. subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "cDC" EXACT [] synonym: "DC1" EXACT [] @@ -2259,6 +2328,7 @@ id: CL:0001065 name: innate lymphoid cell def: "A lymphocyte that lacks characteristic T cell, B cell, myeloid cell, and dendritic cell markers, that functions as part of the innate immune response to produce cytokines and other effector responses." [GOC:add, GOC:dsd, PMID:23292121, PMID:23348417] subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas is_a: CL:0000542 ! lymphocyte intersection_of: CL:0000542 ! lymphocyte @@ -2310,6 +2380,7 @@ relationship: dc-contributor https://orcid.org/0000-0001-9990-8331 id: CL:0002009 name: macrophage dendritic cell progenitor def: "A progenitor cell that can give rise to plasmacytoid and myeloid dendritic cells, and to monocytes and macrophages." [GOC:tfm, PMID:19273628] +subset: cellxgene_subset synonym: "MDP" EXACT [] is_a: CL:0000763 ! myeloid cell is_a: CL:0002032 {is_inferred="true"} ! hematopoietic oligopotent progenitor cell @@ -2328,6 +2399,7 @@ id: CL:0002028 name: basophil mast progenitor cell def: "A cell type that can give rise to basophil and mast cells. This cell is CD34-positive, CD117-positive, CD125-positive, FceRIa-negative, and T1/ST2-negative, and expresses Gata-1, Gata-2, C/EBPa" [GOC:ak, GOC:dsd, GOC:tfm, PMCID:PMC1312421] comment: There may be an intermediate cell type. These cells also CD13-positive, CD16-positive, CD32-positive, and integrin beta 7-positive. Transcription factors: GATA1-positive, MCP-1-positive, mitf-positive, PU.1-positive, and CEBP/a-low. +subset: cellxgene_subset synonym: "BMCP" EXACT [] is_a: CL:0000763 ! myeloid cell is_a: CL:0002191 ! granulocytopoietic cell @@ -2425,6 +2497,7 @@ id: CL:0002092 name: bone marrow cell def: "A cell found in the bone marrow. This can include fibroblasts, macrophages, adipocytes, osteoblasts, osteoclasts, endothelial cells and hematopoietic cells." [GOC:tfm, ISBN:0618947256] comment: MH consider whether bone marrow cells are bone cells in the structural sense vs. being part of bone organ sense. +subset: cellxgene_subset xref: BTO:0004850 xref: FMA:83621 xref: MESH:D001854 @@ -2440,6 +2513,7 @@ id: CL:0002139 name: endothelial cell of vascular tree def: "An endothelial cell of the vascular tree, which includes blood vessels and lymphatic vessels." [GOC:dsd, GOC:tfm, PMID:12768659] comment: These cells are reportedly CD31-positive, CD34-positive, CD144-positive, TAL1-positive. +subset: cellxgene_subset synonym: "cubodial endothelial cell of vascular tree" NARROW [] synonym: "vascular endothelial cell" EXACT [] xref: BTO:0001854 @@ -2453,6 +2527,7 @@ creation_date: 2010-08-24T02:06:40Z id: CL:0002191 name: granulocytopoietic cell def: "A cell involved in the formation of a granulocyte." [GOC:tfm] +subset: cellxgene_subset xref: FMA:83519 is_a: CL:0000839 {is_inferred="true"} ! myeloid lineage restricted progenitor cell intersection_of: CL:0000839 ! myeloid lineage restricted progenitor cell @@ -2500,6 +2575,7 @@ creation_date: 2010-09-10T03:04:42Z id: CL:0002319 name: neural cell def: "A cell that is part of the nervous system." [GOC:tfm, ISBN:0618947256] +subset: cellxgene_subset xref: CALOHA:TS-2040 xref: FMA:70333 is_a: CL:0000000 ! cell @@ -2513,6 +2589,7 @@ creation_date: 2010-09-15T01:34:57Z id: CL:0002320 name: connective tissue cell def: "A cell of the supporting or framework tissue of the body, arising chiefly from the embryonic mesoderm and including adipose tissue, cartilage, and bone." [GOC:tfm, ISBN:0618947256] +subset: cellxgene_subset xref: CALOHA:TS-2096 xref: FMA:63875 xref: MESH:D003239 @@ -2539,6 +2616,7 @@ id: CL:0002420 name: immature T cell def: "A T cell that has not completed T cell selection." [GOC:tfm] subset: blood_and_immune_upper_slim +subset: cellxgene_subset synonym: "immature T-cell" EXACT [] xref: BTO:0001372 xref: CALOHA:TS-1042 @@ -2629,12 +2707,14 @@ creation_date: 2012-06-27T08:27:35Z id: CL:0008001 name: hematopoietic precursor cell def: "Any hematopoietic cell that is a precursor of some other hematopoietic cell type." [GOC:dos] +subset: cellxgene_subset is_a: CL:0000988 ! hematopoietic cell [Term] id: CL:0008019 name: mesenchymal cell def: "A non-polarised cell precursor cell that is part of some mesenchyme, is associated with the cell matrix but is not connected to other cells and is capable of migration." [] +subset: cellxgene_subset subset: human_reference_atlas synonym: "mesenchyme cell" EXACT [] is_a: CL:0000219 ! motile cell @@ -2654,6 +2734,7 @@ relationship: seeAlso https://github.com/obophenotype/cell-ontology/issues/786 id: CL:0011012 name: neural crest cell def: "A cell of the neural crest. Neural crest cells are multipotent. Premigratory neural crest cells are found at the neural plate boarder, some of which will undergo ectomesynchymal transition and delamination to form migratory neural crest cells." [https://orcid.org/0000-0001-5208-3432, https://orcid.org/0000-0002-9900-7880] +subset: cellxgene_subset is_a: CL:0000048 ! multi fate stem cell is_a: CL:0002321 ! embryonic cell (metazoa) @@ -2661,6 +2742,7 @@ is_a: CL:0002321 ! embryonic cell (metazoa) id: CL:0011026 name: progenitor cell def: "A precursor cell that has a tendency to differentiate into a specific type of cell. They are descendants of stem cells, only they are more constrained in their differentiation potential or capacity for self-renewal, and are often more limited in both senses." [https://doi.org/10.1016/B978-0-12-409503-8.00002-0, ISBN:978-1-62808-994-3] +subset: cellxgene_subset is_a: CL:0011115 ! precursor cell intersection_of: CL:0011115 ! precursor cell intersection_of: develops_from CL:0000034 ! stem cell @@ -2672,6 +2754,7 @@ id: CL:0011115 name: precursor cell def: "A cell that, by division or terminal differentiation, can give rise to other cell types." [GOC:dos] comment: Work is needed on GO 'cell differentiation' before it is clear whether the equivalent class definition 'native cell' that capable_of some 'cell differentiation' works. Also, may want to consider merging this with non-terminally differentiated cell. +subset: cellxgene_subset is_a: CL:0000000 ! cell intersection_of: CL:0000000 ! cell intersection_of: capable_of GO:0030154 ! cell differentiation @@ -2747,17 +2830,6 @@ relationship: bearer_of PATO:0070047 ! polychromatophilic relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2009-12-28T04:25:23Z -[Term] -id: CL:0017505 -name: increased nucleus size -def: "A nucleus size quality which is relatively high compared to the amount of cytoplasm present in the same cell." [GOC:tfm] -is_a: GO:0005634 ! nucleus -intersection_of: GO:0005634 ! nucleus -intersection_of: bearer_of PATO:0000586 ! increased size -relationship: bearer_of PATO:0000586 ! increased size -relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 -creation_date: 2009-12-23T10:53:24Z - [Term] id: CL:0017508 name: cartwheel heterochromatin @@ -2783,6 +2855,7 @@ relationship: part_of UBERON:0012429 ! hematopoietic tissue id: CL:2000001 name: peripheral blood mononuclear cell def: "A leukocyte with a single non-segmented nucleus in the mature form found in the circulatory pool of blood." [GOC:TermGenie] +subset: cellxgene_subset is_a: CL:0000080 ! circulating cell is_a: CL:0000842 ! mononuclear cell intersection_of: CL:0000842 ! mononuclear cell @@ -3866,7 +3939,7 @@ id: GO:0005575 name: cellular_component namespace: cellular_component alt_id: GO:0008372 -def: "A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex)." [GOC:pdt] +def: "A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex)." [GOC:pdt] comment: Note that, in addition to forming the root of the cellular component ontology, this term is recommended for the annotation of gene products whose cellular component is unknown. When this term is used for annotation, it indicates that no information was available about the cellular component of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this. subset: goslim_candida subset: goslim_chembl @@ -3897,8 +3970,8 @@ subset: goslim_metagenomics subset: goslim_mouse subset: goslim_pir subset: goslim_plant +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset synonym: "extracellular" EXACT [] xref: Wikipedia:Extracellular is_a: GO:0110165 ! cellular anatomical entity @@ -3957,7 +4030,7 @@ comment: Note that for multicellular organisms, the extracellular space refers t subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "intercellular space" RELATED [] xref: NIF_Subcellular:sao1425028079 is_a: GO:0110165 ! cellular anatomical entity @@ -4021,8 +4094,8 @@ subset: goslim_flybase_ribbon subset: goslim_generic subset: goslim_metagenomics subset: goslim_pir +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset synonym: "chromatid" RELATED [] synonym: "interphase chromosome" NARROW [] synonym: "prophase chromosome" NARROW [] @@ -4056,8 +4129,8 @@ subset: goslim_chembl subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset xref: Wikipedia:Cytoplasm is_a: GO:0110165 ! cellular anatomical entity relationship: part_of GO:0005622 ! intracellular anatomical structure @@ -4142,8 +4215,8 @@ subset: goslim_generic subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset synonym: "free ribosome" NARROW [NIF_Subcellular:sao1139385046] synonym: "membrane bound ribosome" NARROW [NIF_Subcellular:sao1291545653] synonym: "ribosomal RNA" RELATED [] @@ -4168,8 +4241,8 @@ subset: goslim_generic subset: goslim_metagenomics subset: goslim_mouse subset: goslim_plant +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset synonym: "bacterial inner membrane" NARROW [] synonym: "cell membrane" EXACT [] synonym: "cellular membrane" EXACT [NIF_Subcellular:sao6433132645] @@ -4222,8 +4295,8 @@ def: "Any process in which a new genotype is formed by reassortment of genes res subset: goslim_drosophila subset: goslim_generic subset: goslim_pombe +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset is_a: GO:0006259 ! DNA metabolic process [Term] @@ -4240,7 +4313,7 @@ subset: goslim_drosophila subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "protein anabolism" EXACT [] synonym: "protein biosynthesis" EXACT [] synonym: "protein biosynthetic process" EXACT [] @@ -4312,7 +4385,7 @@ subset: goslim_chembl subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "single-organism transport" RELATED [] is_a: GO:0051234 ! establishment of localization property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20292" xsd:anyURI @@ -4757,9 +4830,9 @@ xref: Wikipedia:Coagulation is_a: GO:0007599 ! hemostasis is_a: GO:0050817 ! coagulation intersection_of: GO:0050817 ! coagulation -intersection_of: has_primary_output UBERON:0010210 ! blood clot -relationship: has_primary_output UBERON:0010210 ! blood clot +intersection_of: results_in_assembly_of UBERON:0010210 ! blood clot relationship: part_of GO:0042060 ! wound healing +relationship: results_in_assembly_of UBERON:0010210 ! blood clot [Term] id: GO:0007599 @@ -4834,7 +4907,7 @@ id: GO:0008219 name: cell death namespace: biological_process def: "Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538)." [GOC:mah, GOC:mtg_apoptosis, PMID:25236395] -comment: This term should not be used for direct annotation, it is currently kept in GO as a placeholder for describing cell death phenotypes in uPHENO. When information is provided on a programmed cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'). Unintentional cell death, i.e. cell death caused by injury, ageing, or cell phenotypes observed as a result of a pathological mutation in an essential gene should NOT be annotated using GO terms. +comment: This term should not be used for direct annotation, it is currently kept in GO as a placeholder for describing cell death phenotypes in uPHENO. When information is provided on a programmed cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'). Unintentional cell death, i.e. cell death caused by injury, ageing, or cell phenotypes observed as a result of a pathological mutation in an essential gene should NOT be annotated using GO terms. subset: gocheck_do_not_annotate synonym: "accidental cell death" RELATED [] synonym: "necrosis" RELATED [] @@ -5038,7 +5111,7 @@ subset: goslim_drosophila subset: goslim_generic subset: goslim_mouse subset: goslim_plant -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "caspase-independent apoptosis" RELATED [] synonym: "caspase-independent cell death" NARROW [] synonym: "non-apoptotic programmed cell death" NARROW [] @@ -5439,8 +5512,8 @@ subset: goslim_flybase_ribbon subset: goslim_generic subset: goslim_mouse subset: goslim_pombe +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset synonym: "biological signaling" EXACT [] synonym: "signaling process" EXACT [] synonym: "signalling" EXACT [] @@ -5467,7 +5540,7 @@ id: GO:0030030 name: cell projection organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon." [GOC:jl, GOC:mah, http://www.cogsci.princeton.edu/~wn/] -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "cell projection organisation" EXACT [] synonym: "cell projection organization and biogenesis" RELATED [GOC:mah] synonym: "cell surface structure organization and biogenesis" RELATED [GOC:mah] @@ -5822,7 +5895,7 @@ subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_pir -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "matrisome" NARROW [] synonym: "proteinaceous extracellular matrix" EXACT [] xref: NIF_Subcellular:nlx_subcell_20090513 @@ -6467,7 +6540,7 @@ subset: goslim_agr subset: goslim_flybase_ribbon subset: goslim_mouse subset: goslim_pir -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "cell process" BROAD [] synonym: "cellular process" BROAD [] synonym: "cellular projection" EXACT [] @@ -6504,12 +6577,14 @@ alt_id: GO:0034960 alt_id: GO:0043283 alt_id: GO:0044259 def: "The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:mah] +subset: gocheck_do_not_annotate subset: goslim_pir synonym: "biopolymer metabolic process" EXACT [GOC:mtg_chebi_dec09] synonym: "macromolecule metabolism" EXACT [] synonym: "multicellular organismal macromolecule metabolic process" NARROW [] synonym: "organismal macromolecule metabolism" EXACT [] is_a: GO:0008152 ! metabolic process +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI [Term] id: GO:0043207 @@ -6527,7 +6602,7 @@ def: "Organized structure of distinctive morphology and function. Includes the n subset: goslim_chembl subset: goslim_generic subset: goslim_pir -subset: prokaryote_subset +subset: goslim_prokaryote xref: NIF_Subcellular:sao1539965131 xref: Wikipedia:Organelle is_a: GO:0110165 ! cellular anatomical entity @@ -6690,9 +6765,11 @@ id: GO:0044238 name: primary metabolic process namespace: biological_process def: "The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism." [GOC:go_curators, http://www.metacyc.org] +subset: gocheck_do_not_annotate subset: goslim_pir synonym: "primary metabolism" EXACT [] is_a: GO:0008152 ! metabolic process +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI [Term] id: GO:0044249 @@ -6745,7 +6822,7 @@ synonym: "innate immunity" EXACT [GOC:pg] synonym: "nonspecific immune response" EXACT [] xref: Wikipedia:Innate_immune_system is_a: GO:0006955 ! immune response -is_a: GO:0098542 ! defense response to other organism +is_a: GO:0140546 ! defense response to symbiont [Term] id: GO:0045190 @@ -7125,6 +7202,7 @@ id: GO:0048856 name: anatomical structure development namespace: biological_process def: "The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome." [GO_REF:0000021] +subset: gocheck_do_not_annotate subset: goslim_chembl subset: goslim_generic subset: goslim_plant @@ -7133,6 +7211,7 @@ is_a: GO:0032502 ! developmental process intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of UBERON:0000061 ! anatomical structure relationship: results_in_development_of UBERON:0000061 ! anatomical structure +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI [Term] id: GO:0048869 @@ -7150,7 +7229,7 @@ def: "Any process involved in the controlled self-propelled movement of a cell t subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "cell locomotion" EXACT [] synonym: "cell movement" RELATED [] synonym: "movement of a cell" EXACT [] @@ -7329,7 +7408,7 @@ subset: goslim_agr subset: goslim_flybase_ribbon subset: goslim_mouse subset: goslim_pir -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "physiological response to stimulus" EXACT [] is_a: GO:0008150 ! biological_process @@ -7541,7 +7620,7 @@ def: "A compound molecular function in which an effector function is controlled subset: gocheck_do_not_manually_annotate subset: goslim_generic subset: goslim_pir -subset: prokaryote_subset +subset: goslim_prokaryote is_a: GO:0003674 ! molecular_function [Term] @@ -7620,7 +7699,7 @@ subset: goslim_drosophila subset: goslim_generic subset: goslim_pir subset: goslim_pombe -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "cellular membrane organisation" EXACT [] synonym: "cellular membrane organization" EXACT [] synonym: "membrane organisation" EXACT [GOC:mah] @@ -7686,7 +7765,7 @@ subset: goslim_generic subset: goslim_metagenomics subset: goslim_pir subset: goslim_pombe -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "cellular macromolecule complex assembly" RELATED [] synonym: "cellular protein complex assembly" EXACT [] synonym: "cellular protein-containing complex assembly" RELATED [] @@ -7794,10 +7873,12 @@ id: GO:0071704 name: organic substance metabolic process namespace: biological_process def: "The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon." [GOC:mah] +subset: gocheck_do_not_annotate synonym: "organic molecular entity metabolic process" EXACT [] synonym: "organic molecular entity metabolism" EXACT [] synonym: "organic substance metabolism" EXACT [] is_a: GO:0008152 ! metabolic process +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI created_by: mah creation_date: 2010-03-08T03:32:18Z @@ -7881,7 +7962,7 @@ creation_date: 2010-09-10T01:39:16Z id: GO:0071944 name: cell periphery namespace: cellular_component -def: "The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures." [GOC:pdt] +def: "The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures." [GOC:pdt] subset: goslim_flybase_ribbon is_a: GO:0110165 ! cellular anatomical entity created_by: mah @@ -8002,7 +8083,7 @@ namespace: biological_process alt_id: GO:0009814 def: "Reactions triggered in response to the presence of another organism that act to protect the cell or organism from damage caused by that organism." [GOC:dos] subset: goslim_generic -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "defence response incompatible interaction" NARROW [] synonym: "defence response to pathogen, incompatible interaction" NARROW [] synonym: "defense response, incompatible interaction" NARROW [] @@ -8217,6 +8298,7 @@ subset: goslim_pir is_a: GO:0005575 ! cellular_component is_a: UBERON:0000061 ! anatomical structure property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24200" xsd:anyURI +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI created_by: kmv creation_date: 2019-08-12T18:01:37Z @@ -8317,6 +8399,16 @@ relationship: has_target_start_location GO:0005622 ! intracellular anatomical st created_by: pg creation_date: 2019-05-22T11:20:45Z +[Term] +id: GO:0140546 +name: defense response to symbiont +namespace: biological_process +def: "Reactions triggered in response to the presence of a symbiont that act to protect or prevent damage to the host." [GOC:pg] +is_a: GO:0098542 ! defense response to other organism +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20261" xsd:anyURI +created_by: pg +creation_date: 2020-11-11T17:19:06Z + [Term] id: GO:1901576 name: organic substance biosynthetic process @@ -8817,30 +8909,6 @@ subset: attribute_slim synonym: "relational shape quality" EXACT [] is_a: PATO:0000051 ! morphology -[Term] -id: PATO:0000068 -name: qualitative -namespace: quality -comment: TODO: define this or obsolete it and move children somewhere else. -is_a: PATO:0000001 ! quality - -[Term] -id: PATO:0000069 -name: deviation (from_normal) -namespace: quality -def: "A quality inhering in a bearer by virtue of the whether the bearer differs from normal or average." [PATOC:GVG] -subset: attribute_slim -is_a: PATO:0000068 ! qualitative - -[Term] -id: PATO:0000117 -name: size -namespace: quality -def: "A morphology quality inhering in a bearer by virtue of the bearer's physical magnitude." [WordNet:WordNet] -subset: attribute_slim -subset: scalar_slim -is_a: PATO:0000051 ! morphology - [Term] id: PATO:0000141 name: structure @@ -8885,36 +8953,6 @@ synonym: "round" RELATED [] synonym: "rounded" RELATED [] is_a: PATO:0000947 ! elliptic -[Term] -id: PATO:0000461 -name: normal -namespace: quality -def: "A quality inhering in a bearer by virtue of the bearer's exhibiting no deviation from normal or average." [PATOC:GVG] -subset: abnormal_slim -subset: mpath_slim -subset: value_slim -synonym: "average" RELATED [] -is_a: PATO:0000068 ! qualitative -property_value: RO:0002604 PATO:0000460 - -[Term] -id: PATO:0000586 -name: increased size -namespace: quality -alt_id: PATO:0001202 -def: "A size quality which is relatively high." [PATOC:GVG] -subset: value_slim -synonym: "big" RELATED [] -synonym: "enlarged" RELATED [] -synonym: "expanded" RELATED [] -synonym: "great" RELATED [] -synonym: "large" RELATED [] -is_a: PATO:0000117 ! size -is_a: PATO:0002305 ! increased object quality -intersection_of: PATO:0000117 ! size -intersection_of: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal -property_value: RO:0002604 PATO:0000587 - [Term] id: PATO:0000947 name: elliptic @@ -9284,32 +9322,6 @@ is_a: PATO:0002078 ! hollow relationship: dc-contributor https://orcid.org/0000-0002-2061-091X creation_date: 2011-06-08T06:33:50Z -[Term] -id: PATO:0002300 -name: increased quality -namespace: quality -def: "A quality that has a value that is increased compared to normal or average." [PATOC:GVG] -is_a: PATO:0000069 ! deviation (from_normal) -intersection_of: PATO:0000001 ! quality -intersection_of: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal -relationship: dc-contributor https://orcid.org/0000-0002-2061-091X -relationship: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal -property_value: RO:0002604 PATO:0002301 -creation_date: 2011-06-16T06:39:43Z - -[Term] -id: PATO:0002305 -name: increased object quality -namespace: quality -def: "A quality of an object that has a value that is increased compared to normal or average." [PATOC:GVG] -is_a: PATO:0001241 ! physical object quality -is_a: PATO:0002300 ! increased quality -intersection_of: PATO:0001241 ! physical object quality -intersection_of: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal -relationship: dc-contributor https://orcid.org/0000-0002-2061-091X -property_value: RO:0002604 PATO:0002303 -creation_date: 2011-06-16T06:54:01Z - [Term] id: PATO:0002318 name: superelliptic @@ -9362,6 +9374,16 @@ comment: A complete coverage of this domain would subclasses homopolymeric, copo subset: value_slim is_a: PATO:0000141 ! structure +[Term] +id: PATO:0040072 +name: high nuclear/cytoplasmic ratio +namespace: quality +def: "A quality inhering in a cell by virtue of the cell having a high nuclear/cytoplasmic ratio." [http://lymerick.net/blood-cells.pdf, Wikipedia:NC_ratio&oldid=931936284] +comment: A high nuclear/cytolasmic ratio is 70% or higher. +synonym: "high N:C ratio" EXACT [] +is_a: PATO:0001396 ! cellular quality +created_by: http://orcid.org/0000-0001-5208-3432 + [Term] id: PATO:0070044 name: anatomical structure quality @@ -10695,7 +10717,7 @@ xref: BILA:0000003 xref: CARO:0000003 xref: EHDAA2:0003003 xref: EMAPA:0 -xref: FBbt:00007001 +xref: FBbt:00007001 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:305751 xref: FMA:67135 xref: GAID:781 @@ -10950,13 +10972,13 @@ synonym: "fertilized egg stage" RELATED [] synonym: "one cell stage" EXACT [] synonym: "one-cell stage" RELATED [VHOG:0000745] synonym: "zygote" RELATED [VHOG:0000745] -synonym: "zygotum" RELATED LATIN [Wikipedia:Zygote] +synonym: "zygotum" RELATED OMO:0003011 [Wikipedia:Zygote] xref: BilaDO:0000005 xref: BILS:0000106 xref: EFO:0001322 xref: EHDAA:27 xref: FBdv:00005288 -xref: IDOMAL:0000302 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: IDOMAL:0000302 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: NCIT:C12601 xref: PdumDv:0000100 xref: VHOG:0000745 @@ -11104,13 +11126,13 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "adult mouth" NARROW [] -synonym: "cavital oralis" RELATED LATIN [Wikipedia:Mouth] +synonym: "cavital oralis" RELATED OMO:0003011 [Wikipedia:Mouth] synonym: "cavitas oris" RELATED [BTO:0001090] synonym: "cavum oris" RELATED [BTO:0001090] synonym: "mouth cavity" RELATED [BTO:0001090] synonym: "oral region" RELATED [EHDAA2:0001326] synonym: "oral vestibule" RELATED [BTO:0001090] -synonym: "regio oralis" EXACT LATIN [BTO:0004698, FMA:49184, FMA:TA] +synonym: "regio oralis" EXACT OMO:0003011 [BTO:0004698, FMA:49184, FMA:TA] synonym: "rima oris" RELATED [BTO:0001090] synonym: "stoma" RELATED [] synonym: "stomatodaeum" RELATED [VHOG:0000812] @@ -11125,7 +11147,7 @@ xref: EFO:0000825 xref: EHDAA2:0001326 xref: EHDAA:542 xref: EMAPA:16262 -xref: FBbt:00003126 +xref: FBbt:00003126 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:49184 xref: GAID:75 xref: galen:Mouth @@ -11308,7 +11330,7 @@ xref: CALOHA:TS-2101 xref: CARO:0000004 xref: EHDAA2:0003004 xref: EMAPA:35178 -xref: FBbt:00007019 +xref: FBbt:00007019 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:9669 xref: galen:BodySubstance xref: HAO:0000004 @@ -11343,7 +11365,7 @@ xref: AEO:0000005 xref: BILA:0000005 xref: CARO:0000005 xref: EHDAA2:0003005 -xref: FBbt:00007017 +xref: FBbt:00007017 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:5897 xref: HAO:0000005 xref: NCIT:C94478 @@ -11371,7 +11393,7 @@ xref: AEO:0000006 xref: BILA:0000006 xref: CARO:0000006 xref: EHDAA2:0003006 -xref: FBbt:00007016 +xref: FBbt:00007016 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:67165 xref: HAO:0000006 xref: TAO:0001836 @@ -11397,7 +11419,7 @@ xref: AEO:0000007 xref: BILA:0000007 xref: CARO:0000007 xref: EHDAA2:0003007 -xref: FBbt:00007015 +xref: FBbt:00007015 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:67112 xref: HAO:0000007 xref: TAO:0001835 @@ -11435,11 +11457,11 @@ xref: EHDAA2:0003011 xref: EHDAA:392 xref: EMAPA:16103 xref: EV:0100000 -xref: FBbt:00004856 +xref: FBbt:00004856 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:7149 xref: galen:AnatomicalSystem xref: HAO:0000011 -xref: IDOMAL:0002460 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: IDOMAL:0002460 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: MA:0000003 xref: NCIT:C12919 xref: SCTID:278195005 @@ -11490,7 +11512,7 @@ xref: EHDAA2:0003191 xref: EHDAA:1 xref: EMAPA:25765 xref: EV:0100016 -xref: FBbt:00000001 +xref: FBbt:00000001 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:256135 xref: galen:Organism xref: HAO:0000012 @@ -11535,7 +11557,7 @@ xref: CARO:0000032 xref: EFO:0000808 xref: EHDAA2:0003032 xref: EMAPA:36031 -xref: FBbt:00007009 +xref: FBbt:00007009 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:7153 xref: galen:BodyPart xref: HAO:0000032 @@ -11571,7 +11593,7 @@ xref: AEO:0000040 xref: BILA:0000040 xref: CARO:0000040 xref: EHDAA2:0003040 -xref: FBbt:00007013 +xref: FBbt:00007013 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:63863 xref: HAO:0000040 xref: TAO:0000382 @@ -11591,8 +11613,7 @@ namespace: uberon def: "Anatomical group whose component anatomical structures lie in close proximity to each other." [FBbt:00007277] subset: common_anatomy subset: upper_level -xref: FBbt:00007277 -xref: IDOMAL:0002461 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: FBbt:00007277 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: VHOG:0001737 is_a: UBERON:0034923 ! disconnected anatomical group relationship: present_in_taxon NCBITaxon:33090 @@ -11619,7 +11640,7 @@ xref: CALOHA:TS-2090 xref: CARO:0000043 xref: EHDAA2:0003043 xref: EMAPA:35868 -xref: FBbt:00007003 +xref: FBbt:00007003 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:9637 xref: galen:Tissue xref: HAO:0000043 @@ -11654,7 +11675,7 @@ xref: AEO:0000055 xref: BILA:0000055 xref: CARO:0000055 xref: EHDAA2:0003055 -xref: FBbt:00007010 +xref: FBbt:00007010 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: HAO:0000055 xref: TAO:0001488 xref: TGMA:0001847 @@ -11687,7 +11708,7 @@ xref: CALOHA:TS-0288 xref: CARO:0000066 xref: EHDAA2:0003066 xref: EMAPA:32738 -xref: FBbt:00007005 +xref: FBbt:00007005 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:9639 xref: GAID:402 xref: HAO:0000066 @@ -11817,11 +11838,11 @@ xref: EHDAA2:0000002 xref: EHDAA2_RETIRED:0003236 xref: EHDAA:38 xref: EMAPA:16039 -xref: FBbt:00000052 +xref: FBbt:00000052 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:69068 xref: GAID:963 xref: http://neurolex.org/wiki/Category\:Embryonic_organism -xref: IDOMAL:0000646 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: IDOMAL:0000646 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: MAT:0000226 xref: MESH:D004622 xref: MIAA:0000019 @@ -11861,7 +11882,7 @@ xref: AAO:0000480 xref: BILA:0000035 xref: BTO:0000556 xref: EMAPA:36033 -xref: FBbt:00000110 +xref: FBbt:00000110 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:69069 xref: GAID:1303 xref: MESH:D005855 @@ -11896,7 +11917,7 @@ xref: EFO:0000414 xref: EHDAA2:0000428 xref: EMAPA:16069 xref: EV:0100003 -xref: FBbt:00000111 +xref: FBbt:00000111 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:69070 xref: GAID:1304 xref: MAT:0000155 @@ -11937,7 +11958,7 @@ xref: EFO:0002545 xref: EHDAA2:0000436 xref: EMAPA:16062 xref: EV:0100005 -xref: FBbt:00000125 +xref: FBbt:00000125 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:69071 xref: GAID:1305 xref: MAT:0000175 @@ -11983,7 +12004,7 @@ xref: EHDAA:160 xref: EHDAA:183 xref: EMAPA:16083 xref: EV:0100006 -xref: FBbt:00000126 +xref: FBbt:00000126 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:69072 xref: GAID:522 xref: MAT:0000174 @@ -12027,7 +12048,7 @@ synonym: "stomodeal-hypophyseal primordium" BROAD [XAO:0000269] xref: BTO:0004224 xref: EHDAA2:0001929 xref: EMAPA:16263 -xref: FBbt:00000439 +xref: FBbt:00000439 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:295846 xref: NCIT:C34306 xref: TAO:0001290 @@ -12174,7 +12195,7 @@ xref: BTO:0000058 xref: CALOHA:TS-1293 xref: EFO:0000793 xref: EV:0100056 -xref: FBbt:00005055 +xref: FBbt:00005055 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:7152 xref: GAID:278 xref: galen:DigestiveSystem @@ -12213,9 +12234,10 @@ namespace: uberon def: "Organ system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis[WP]." [Wikipedia:Circulatory_system] subset: human_reference_atlas subset: uberon_slim -synonym: "systema cardiovasculare" RELATED LATIN [Wikipedia:Circulatory_system] +synonym: "systema cardiovasculare" RELATED OMO:0003011 [Wikipedia:Circulatory_system] xref: AAO:0000959 xref: CALOHA:TS-2103 +xref: MESH:D002319 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} xref: VHOG:0001248 xref: Wikipedia:Circulatory_system is_a: UBERON:0000467 ! anatomical system @@ -12252,7 +12274,7 @@ synonym: "muscles" RELATED [] synonym: "muscles set" EXACT [] synonym: "musculature" EXACT [] synonym: "musculature system" RELATED [] -synonym: "musculi" EXACT LATIN [FMA:32558, FMA:TA] +synonym: "musculi" EXACT OMO:0003011 [FMA:32558, FMA:TA] synonym: "set of muscles" EXACT [FMA:32558] synonym: "set of skeletal muscles" EXACT [MA:0000165] xref: AAO:0011066 @@ -12283,12 +12305,13 @@ namespace: uberon def: "The nervous system is an organ system containing predominantly neuron and glial cells. In bilaterally symmetrical organism, it is arranged in a network of tree-like structures connected to a central body. The main functions of the nervous system are to regulate and control body functions, and to receive sensory input, process this information, and generate behavior [CUMBO]." [BIRNLEX:844, ISBN:0-14-051288-8, ISBN:3110148986, NLM:nervous+system, WB:rynl, Wikipedia:Nervous_system, ZFIN:curator] subset: cumbo subset: efo_slim +subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "nerve net" NARROW [Wikipedia:Nerve_net] synonym: "neurological system" EXACT [GO:0050877] -synonym: "systema nervosum" RELATED LATIN [Wikipedia:Nervous_system] +synonym: "systema nervosum" RELATED OMO:0003011 [Wikipedia:Nervous_system] xref: AAO:0000324 xref: BILA:0000079 xref: BIRNLEX:844 @@ -12299,7 +12322,7 @@ xref: EHDAA2:0001246 xref: EHDAA:826 xref: EMAPA:16469 xref: EV:0100162 -xref: FBbt:00005093 +xref: FBbt:00005093 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:7157 xref: GAID:466 xref: MA:0000016 @@ -12328,6 +12351,7 @@ relationship: has_part CL:0000540 ! neuron relationship: immediate_transformation_of UBERON:0016880 {source="Bgee:AN"} ! future nervous system relationship: never_in_taxon NCBITaxon:6040 relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa +relationship: present_in_taxon NCBITaxon:9606 property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/b/b2/TE-Nervous_system_diagram.svg" xsd:anyURI property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/b/ba/Nervous_system_diagram.png" xsd:anyURI property_value: UBPROP:0000001 "A regulatory system of the body that consists of neurons and neuroglial cells. The nervous system is divided into two parts, the central nervous system (CNS) and the peripheral nervous system (PNS). (Source: BioGlossary, www.Biology-Text.com)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000396", ontology="TAO", source="ZFIN:curator"} @@ -12343,13 +12367,14 @@ namespace: uberon def: "The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the neural tube derivatives: the brain and spinal cord. In invertebrates it includes central ganglia plus nerve cord." [GO:0021551, http://www.frontiersinzoology.com/content/7/1/29, https://sourceforge.net/p/geneontology/ontology-requests/11422/] subset: cumbo subset: efo_slim +subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "cerebrospinal axis" NARROW [FMA:55675] synonym: "CNS" EXACT OMO:0003000 [] synonym: "neuraxis" RELATED [FMA:55675] -synonym: "systema nervosum centrale" EXACT LATIN [FMA:55675, FMA:TA] +synonym: "systema nervosum centrale" EXACT OMO:0003011 [FMA:55675, FMA:TA] xref: AAO:0000090 xref: BAMS:CNS xref: BILA:0000080 @@ -12362,7 +12387,7 @@ xref: EHDAA:828 xref: EMAPA:16470 xref: EMAPA:16754 xref: EV:0100163 -xref: FBbt:00005094 +xref: FBbt:00005094 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:55675 xref: GAID:570 xref: MA:0000167 @@ -12383,6 +12408,7 @@ relationship: immediate_transformation_of UBERON:0016879 {source="Bgee:AN"} ! fu relationship: never_in_taxon NCBITaxon:147099 {source="Wikipedia:Acoelomorpha"} relationship: only_in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of UBERON:0001016 ! nervous system +relationship: present_in_taxon NCBITaxon:9606 property_value: UBPROP:0000001 "Part of the nervous system which includes the brain and spinal cord.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000090", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000001 "The brain and spinal cord. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000012", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "The central nervous system (CNS) is the part of the nervous system which includes the brain, spinal cord, and nerve cell layer of the retina (CUMBO)." xsd:string {source="BIRNLEX:1099"} @@ -12405,7 +12431,7 @@ xref: AEO:0000171 xref: BTO:0001886 xref: EFO:0001652 xref: EHDAA2:0003171 -xref: FBbt:00005495 +xref: FBbt:00005495 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:86589 xref: MAT:0000482 xref: NCIT:C34275 @@ -12425,7 +12451,7 @@ subset: uberon_slim subset: vertebrate_core synonym: "neural primordium" RELATED [] synonym: "presumptive central nervous system" RELATED [] -synonym: "tubus neuralis" RELATED LATIN [Wikipedia:Neural_tube] +synonym: "tubus neuralis" RELATED OMO:0003011 [Wikipedia:Neural_tube] xref: AAO:0010617 xref: BTO:0001057 xref: CALOHA:TS-2371 @@ -12437,7 +12463,7 @@ xref: EMAPA:16164 xref: EMAPA:16757 xref: FMA:293882 xref: MAT:0000069 -xref: MESH:D054259 +xref: MESH:D054259 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: MIAA:0000069 xref: NCIT:C34226 xref: neuronames:1365 @@ -12473,7 +12499,7 @@ xref: BILA:0000000 xref: BIRNLEX:6 xref: CARO:0000000 xref: EHDAA2:0002229 -xref: FBbt:10000000 +xref: FBbt:10000000 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:62955 xref: HAO:0000000 xref: MA:0000001 @@ -12613,10 +12639,11 @@ xref: BTO:0000545 xref: EHDAA2:0000726 xref: EHDAA:518 xref: EMAPA:16247 -xref: FBbt:00003125 +xref: FBbt:00003125 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:45615 xref: galen:AlimentaryTract xref: MA:0000917 +xref: MESH:D041981 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} xref: NCIT:C34082 xref: TAO:0000112 xref: TGMA:0001819 @@ -12718,7 +12745,7 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "region of vascular tree organ" EXACT [FMA:50722] -synonym: "vas sanguineum" RELATED LATIN [Wikipedia:Blood_vessel] +synonym: "vas sanguineum" RELATED OMO:0003011 [Wikipedia:Blood_vessel] synonym: "vascular element" BROAD [EMAPA:35993] synonym: "vascular tree organ region" EXACT [FMA:50722] xref: AAO:0011004 @@ -12833,7 +12860,7 @@ xref: BILA:0000034 xref: BTO:0000174 xref: CALOHA:TS-2110 xref: EFO:0000461 -xref: FBbt:00004208 +xref: FBbt:00004208 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:69067 xref: GAID:407 xref: MESH:D004628 @@ -12909,6 +12936,7 @@ xref: EMAPA:37721 {source="MA:th"} xref: FMA:71221 xref: MA:0002986 xref: MAT:0000148 +xref: MESH:D013131 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} xref: MIAA:0000148 xref: TAO:0000317 xref: VHOG:0000317 @@ -13021,7 +13049,7 @@ namespace: uberon def: "The part of the coelemic cavity lumen that is enclosed by the walls of the thorax." [UBERON:cjm, Wikipedia:Thoracic_cavity] subset: pheno_slim subset: uberon_slim -synonym: "cavitas thoracis" EXACT LATIN [Wikipedia:Thoracic_cavity] +synonym: "cavitas thoracis" EXACT OMO:0003011 [Wikipedia:Thoracic_cavity] synonym: "cavity of chest" EXACT [] synonym: "cavity of thorax" EXACT [] synonym: "chest cavity" EXACT [] @@ -13069,7 +13097,7 @@ synonym: "ventral body cavity" NARROW [NCBITaxon:7742] xref: AEO:0000186 xref: BTO:0001707 xref: EHDAA2:0000267 -xref: FBbt:00005060 +xref: FBbt:00005060 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:85006 xref: galen:BodyCavity xref: NCIT:C25444 @@ -13095,7 +13123,7 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "embryonic notocord" EXACT [] -synonym: "notochorda" RELATED LATIN [Wikipedia:Notochord] +synonym: "notochorda" RELATED OMO:0003011 [Wikipedia:Notochord] synonym: "notocord" EXACT [ZFA:0000135] xref: AAO:0000327 xref: BTO:0001768 @@ -13154,7 +13182,7 @@ synonym: "epithelial somite" RELATED [https://github.com/obophenotype/uberon/wik synonym: "mesodermal cluster" BROAD [GO:0001756] synonym: "somites" RELATED OMO:0003004 [] synonym: "somitic mesoderm" RELATED [] -synonym: "somitus" RELATED LATIN [Wikipedia:Somite] +synonym: "somitus" RELATED OMO:0003011 [Wikipedia:Somite] xref: AAO:0010569 xref: AEO:0001015 xref: BTO:0001558 @@ -13198,7 +13226,7 @@ comment: Gene notes: Many factors and genes, such as Pax3 (Tremblay et al., 1995 subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "crista neuralis" RELATED LATIN [Wikipedia:Neural_crest] +synonym: "crista neuralis" RELATED OMO:0003011 [Wikipedia:Neural_crest] synonym: "NC" EXACT OMO:0003000 [XAO:0000048] synonym: "neural crest material" RELATED [VHOG:0000057] xref: AAO:0010578 @@ -13244,7 +13272,7 @@ namespace: uberon def: "Embryonic ectoderm that gives rise to nervous tissue." [Wikipedia:Neuroectoderm] subset: uberon_slim subset: vertebrate_core -synonym: "epithelium tubi neuralis; neuroectoderma" RELATED LATIN [Wikipedia:Neuroectoderm] +synonym: "epithelium tubi neuralis; neuroectoderma" RELATED OMO:0003011 [Wikipedia:Neuroectoderm] synonym: "neuaral ectoderm" RELATED [] synonym: "neural ectoderm" EXACT [] synonym: "neuroectoderm" EXACT [] @@ -13258,7 +13286,7 @@ xref: EHDAA:1498 xref: EHDAA:255 xref: EMAPA:16073 xref: EV:0100004 -xref: FBbt:00001057 +xref: FBbt:00001057 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:87657 xref: MAT:0000176 xref: MIAA:0000176 @@ -13286,8 +13314,8 @@ subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "medulla of bone" RELATED [BTO:0000141] -synonym: "medulla ossea" EXACT LATIN [BTO:0000141, FMA:9608] -synonym: "medulla ossium" EXACT LATIN [BTO:0000141, Wikipedia:Bone_marrow] +synonym: "medulla ossea" EXACT OMO:0003011 [BTO:0000141, FMA:9608] +synonym: "medulla ossium" EXACT OMO:0003011 [BTO:0000141, Wikipedia:Bone_marrow] synonym: "medullary bone" RELATED [] xref: AAO:0011007 xref: BTO:0000141 @@ -13523,7 +13551,7 @@ subset: vertebrate_core synonym: "blastocyst" RELATED [] synonym: "ectoblast" RELATED [MP:0003886] synonym: "epiblast" EXACT [VHOG:0000243] -synonym: "epiblastus" RELATED LATIN [Wikipedia:Epiblast] +synonym: "epiblastus" RELATED OMO:0003011 [Wikipedia:Epiblast] synonym: "primitive ectoderm" RELATED [VHOG:0000243] xref: BTO:0004593 xref: FMA:296704 @@ -13651,7 +13679,7 @@ def: "A region of embryonic ectodermal cells that lie directly above the notocho subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "lamina neuralis" RELATED LATIN [Wikipedia:Neural_plate] +synonym: "lamina neuralis" RELATED OMO:0003011 [Wikipedia:Neural_plate] synonym: "presumptive central nervous system" RELATED [] xref: AAO:0011072 xref: BTO:0001765 @@ -13661,7 +13689,7 @@ xref: EHDAA:346 xref: EHDAA:902 xref: EMAPA:35593 xref: FMA:293879 -xref: MESH:D054258 +xref: MESH:D054258 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: NCIT:C34225 xref: neuronames:1362 xref: RETIRED_EHDAA2:0001252 @@ -13689,7 +13717,7 @@ def: "The paraxial mesoderm is the mesoderm located bilaterally adjacent to the subset: efo_slim subset: uberon_slim subset: vertebrate_core -synonym: "mesoderma paraxiale" RELATED LATIN [Wikipedia:Paraxial_mesoderm] +synonym: "mesoderma paraxiale" RELATED OMO:0003011 [Wikipedia:Paraxial_mesoderm] synonym: "paraxial mesenchyme" EXACT [https://github.com/obophenotype/uberon/issues/30, https://github.com/obophenotype/uberon/wiki/The-neural-crest, ZFA:0000255] synonym: "somitic mesoderm" EXACT [ISBN:9780878932504] xref: AAO:0010568 @@ -13728,7 +13756,7 @@ synonym: "lateral mesoderm" EXACT [GO:0048368] synonym: "lateral plate" RELATED [] synonym: "lateral plate mesenchyme" RELATED [EHDAA2:0000919] synonym: "LPM" EXACT OMO:0003000 [ZFA:0000121] -synonym: "mesoderma laminae lateralis" RELATED LATIN [Wikipedia:Lateral_plate_mesoderm] +synonym: "mesoderma laminae lateralis" RELATED OMO:0003011 [Wikipedia:Lateral_plate_mesoderm] xref: AAO:0010574 xref: EHDAA2:0000919 xref: EHDAA:379 @@ -13789,10 +13817,10 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "sclerotomes" EXACT OMO:0003004 [TAO:0001080] -synonym: "sclerotomus" RELATED LATIN [Wikipedia:Sclerotome] +synonym: "sclerotomus" RELATED OMO:0003011 [Wikipedia:Sclerotome] xref: AAO:0010571 xref: AEO:0000212 -xref: BTO:0006255 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: BTO:0006255 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: EHDAA2:0003439 xref: EMAPA:31159 xref: FMA:295652 @@ -13843,7 +13871,7 @@ def: "Portion of tissue composed of mesenchymal cells (motile cells that develop subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "mesenchyma" RELATED LATIN [Wikipedia:Mesenchyme] +synonym: "mesenchyma" RELATED OMO:0003011 [Wikipedia:Mesenchyme] synonym: "mesenchymal tissue" EXACT [] synonym: "mesenchyme tissue" EXACT [] synonym: "portion of mesenchymal tissue" EXACT [] @@ -13917,7 +13945,7 @@ def: "Epithelial tubes transport gases, liquids and cells from one site to anoth synonym: "epithelial or endothelial tube" EXACT [] xref: AEO:0000114 xref: EHDAA2:0003114 -xref: FBbt:00007474 +xref: FBbt:00007474 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0000025 ! tube is_a: UBERON:0000483 ! epithelium intersection_of: UBERON:0000483 ! epithelium @@ -14177,6 +14205,7 @@ id: UBERON:0004638 name: blood vessel endothelium namespace: uberon def: "An endothelium that lines the blood vasculature. Other endothelia may line lymph vessels, the heart." [https://orcid.org/0000-0002-6601-2165] +subset: human_reference_atlas subset: pheno_slim subset: vertebrate_core xref: BTO:0000766 @@ -14191,6 +14220,7 @@ is_a: UBERON:0004852 ! cardiovascular system endothelium intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:0001981 ! blood vessel relationship: part_of UBERON:0001981 ! blood vessel +relationship: present_in_taxon NCBITaxon:9606 [Term] id: UBERON:0004716 @@ -14232,7 +14262,7 @@ synonym: "trilaminar disk" RELATED [https://orcid.org/0000-0002-6601-2165] synonym: "trilaminar germ" RELATED [https://orcid.org/0000-0002-6601-2165] xref: BILA:0000060 xref: BTO:0001403 -xref: FBbt:00005317 +xref: FBbt:00005317 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:293108 xref: GAID:1302 xref: MESH:D005775 @@ -14380,7 +14410,7 @@ namespace: uberon def: "Anatomical structure that connects two or more adjacent skeletal elements or hardened body parts." [http://orcid.org/0000-0002-6601-2165] subset: grouping_class synonym: "joint" NARROW [] -xref: FBbt:00005811 +xref: FBbt:00005811 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0034921 ! multi organ part structure relationship: part_of UBERON:0004770 ! articular system @@ -14396,7 +14426,7 @@ synonym: "gut section" RELATED [FBbt:00100315] synonym: "intestinal tract" RELATED [] synonym: "segment of intestinal tract" RELATED [] synonym: "subdivision of alimentary system" RELATED [FMA:71131] -xref: FBbt:00100315 +xref: FBbt:00100315 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:71131 is_a: UBERON:0013522 ! subdivision of tube intersection_of: UBERON:0013522 ! subdivision of tube @@ -14588,7 +14618,7 @@ synonym: "developmental tissue" RELATED [MIAA:0000019] xref: AEO:0000125 xref: CALOHA:TS-2122 xref: EHDAA2:0003125 -xref: FBbt:00007006 +xref: FBbt:00007006 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:292313 xref: MIAA:0000019 is_a: UBERON:0000465 ! material anatomical entity @@ -14605,7 +14635,7 @@ def: "Multi-tissue structure that arises from the heart rudiment and will become subset: vertebrate_core synonym: "early primitive heart tube" NARROW [EMAPA:16208] synonym: "primitive heart tube" EXACT [EMAPA:16215] -xref: BTO:0006179 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: BTO:0006179 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: EHDAA2:0001512 xref: EHDAA:424 xref: EHDAA:436 @@ -14642,7 +14672,7 @@ namespace: uberon def: "An acellular membrane that is part of the epithelium, lies adjacent to the epithelial cells, and is the fusion of the the basal lamina and the reticular lamina." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Basement_membrane] synonym: "basement membrane" RELATED [FMA:63872] synonym: "basement membrane of connective tissue" EXACT [FMA:63872] -synonym: "membrana basalis" EXACT LATIN [Wikipedia:Basement_membrane] +synonym: "membrana basalis" EXACT OMO:0003011 [Wikipedia:Basement_membrane] xref: AAO:0010596 xref: FMA:63872 xref: GAID:915 @@ -14681,7 +14711,7 @@ def: "Subdivision of skeleton which consists of cranial skeleton, set of all ver subset: human_reference_atlas subset: pheno_slim subset: uberon_slim -synonym: "skeleton axiale" RELATED LATIN [Wikipedia:Axial_skeleton] +synonym: "skeleton axiale" RELATED OMO:0003011 [Wikipedia:Axial_skeleton] xref: AAO:0000963 xref: EMAPA:17214 xref: EMAPA:18043 @@ -15105,7 +15135,7 @@ synonym: "organ field" RELATED [] xref: AEO:0000170 xref: EFO:0001649 xref: EHDAA2:0003170 -xref: FBbt:00005426 +xref: FBbt:00005426 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: Wikipedia:Anlage_(biology) is_a: UBERON:0000479 {source="FBbt"} ! tissue is_a: UBERON:0005423 {source="AEO", source="FBbt"} ! developing anatomical structure @@ -15190,7 +15220,7 @@ subset: common_anatomy subset: upper_level synonym: "multicellular structure" EXACT [FBbt:00100313] xref: CARO:0010000 -xref: FBbt:00100313 +xref: FBbt:00100313 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0000061 ! anatomical structure intersection_of: UBERON:0000061 ! anatomical structure intersection_of: has_quality PATO:0001993 ! multicellular @@ -15311,8 +15341,9 @@ name: organ system subdivision namespace: uberon def: "A subdivision of an anatomical system." [http://orcid.org/0000-0002-6601-2165] subset: common_anatomy +subset: human_reference_atlas subset: upper_level -xref: FBbt:00007330 +xref: FBbt:00007330 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:67509 xref: SCTID:91690000 is_a: UBERON:0010000 {source="FBbt"} ! multicellular anatomical structure @@ -15320,6 +15351,7 @@ relationship: part_of UBERON:0000467 ! anatomical system relationship: present_in_taxon NCBITaxon:33090 relationship: present_in_taxon NCBITaxon:33208 ! Metazoa relationship: present_in_taxon NCBITaxon:4751 +relationship: present_in_taxon NCBITaxon:9606 [Term] id: UBERON:0011585 @@ -15451,7 +15483,6 @@ id: UBERON:0013702 name: body proper namespace: uberon def: "The region of the organism associated with the visceral organs." [AEO:0000103] -subset: human_reference_atlas subset: non_informative synonym: "body" RELATED [AEO:0000103] synonym: "whole body" RELATED [BTO:0001489] @@ -15461,7 +15492,6 @@ xref: EMAPA:36031 xref: FMA:231424 is_a: UBERON:0000475 {source="AEO"} ! organism subdivision relationship: part_of UBERON:0013701 ! main body axis -relationship: present_in_taxon NCBITaxon:9606 property_value: UBPROP:0000001 "Cardinal body part, which consists of a maximal set of diverse subclasses of organ and organ part spatially associated with the vertebral column and ribcage. Examples: There is only one body proper[FMA:231424]." xsd:string {source="FMA:231424"} [Term] @@ -15502,7 +15532,7 @@ name: non-connected functional system namespace: uberon def: "An anatomical group whose component structures share a common function." [AEO:0000093, AEO:JB, FBbt:00007278, FBC:DOS] xref: AEO:0000093 -xref: FBbt:00007278 +xref: FBbt:00007278 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0034923 ! disconnected anatomical group [Term] @@ -15628,7 +15658,7 @@ namespace: uberon def: "Material anatomical entity consisting of multiple anatomical structures that are not connected to each other." [CARO:0020000] subset: common_anatomy xref: CARO:0020000 -xref: FBbt:00007276 +xref: FBbt:00007276 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0000465 {source="CARO"} ! material anatomical entity relationship: composed_primarily_of UBERON:0000061 ! anatomical structure relationship: has_component UBERON:0000061 {minCardinality="2"} ! anatomical structure @@ -16052,20 +16082,6 @@ property_value: seeAlso "https://github.com/obophenotype/uberon/wiki/Part-disjoi is_a: RO:0002323 ! mereotopologically related to expand_expression_to: "BFO_0000051 exactly 0 (BFO_0000050 some ?Y)" [] -[Typedef] -id: RO:0002203 -name: develops into -def: "inverse of develops from" [] -subset: RO:0002259 -property_value: IAO:0000114 IAO:0000125 -property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 -property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172 -property_value: IAO:0000117 https://orcid.org/0000-0003-1980-3228 -is_transitive: true -is_a: has_potential_to_develop_into ! has potential to develop into -is_a: RO:0002286 ! developmentally succeeded by -is_a: RO:0002388 ! has potential to directly develop into - [Typedef] id: RO:0002206 name: expressed in @@ -16086,7 +16102,7 @@ def: "inverse of directly develops from" [] subset: RO:0002259 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000118 "developmental precursor of" xsd:string -is_a: RO:0002203 ! develops into +is_a: develops_into ! develops into [Typedef] id: RO:0002222 @@ -16116,7 +16132,7 @@ def: "inverse of has developmental contribution from" [] subset: RO:0002259 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 -holds_over_chain: RO:0002203 part_of +holds_over_chain: develops_into part_of is_a: has_potential_to_developmentally_contribute_to ! has potential to developmentally contribute to is_a: RO:0002286 ! developmentally succeeded by @@ -17401,7 +17417,7 @@ range: BFO:0000004 ! independent continuant is_transitive: true is_a: has_developmental_contribution_from ! has developmental contribution from is_a: RO:0002258 ! developmentally preceded by -inverse_of: RO:0002203 ! develops into +inverse_of: develops_into ! develops into [Typedef] id: develops_from_part_of @@ -17428,6 +17444,22 @@ domain: UBERON:0001062 ! anatomical entity holds_over_chain: directly_develops_from located_in is_a: RO:0002258 ! developmentally preceded by +[Typedef] +id: develops_into +name: develops into +namespace: uberon +def: "inverse of develops from" [] +subset: RO:0002259 +xref: RO:0002203 +property_value: IAO:0000114 IAO:0000125 +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 +property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172 +property_value: IAO:0000117 https://orcid.org/0000-0003-1980-3228 +is_transitive: true +is_a: has_potential_to_develop_into ! has potential to develop into +is_a: RO:0002286 ! developmentally succeeded by +is_a: RO:0002388 ! has potential to directly develop into + [Typedef] id: directly_develops_from name: directly develops from @@ -17762,7 +17794,7 @@ is_a: RO:0002479 ! has part that occurs in id: has_high_plasma_membrane_amount name: obsolete has_high_plasma_membrane_amount def: "OBSOLETE A relation between a cell and molecule or complex such that every instance of the cell has a high number of instances of that molecule expressed on the cell surface. For the formal definition, see Masci et al (PMID:19243617)." [PMID:19243617] -comment: Replaced with RO:0015015, see https://github.com/obophenotype/cell-ontology/issues/1481 +property_value: term_tracker_item https://github.com/obophenotype/cell-ontology/issues/1481 is_obsolete: true replaced_by: RO:0015015 @@ -17789,7 +17821,7 @@ inverse_of: input_of ! input of id: has_low_plasma_membrane_amount name: obsolete has_low_plasma_membrane_amount def: "OBSOLETE A relation between a cell and molecule or complex such that every instance of the cell has a low number of instances of that molecule expressed on the cell surface. For the formal definition, see Masci et al (PMID:19243617)." [PMID:19243617] -comment: Replaced with RO:0015016, see https://github.com/obophenotype/cell-ontology/issues/1481 +property_value: term_tracker_item https://github.com/obophenotype/cell-ontology/issues/1481 is_obsolete: true replaced_by: RO:0015016 @@ -19176,21 +19208,21 @@ is_a: develops_from ! develops from id: transitively_anteriorly_connected_to name: transitively anteriorly connected to namespace: uberon -def: "." [http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern] +property_value: seeAlso "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" xsd:anyURI is_transitive: true [Typedef] id: transitively_distally_connected_to name: transitively distally connected to namespace: uberon -def: "." [http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern] +property_value: seeAlso "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" xsd:anyURI is_transitive: true [Typedef] id: transitively_proximally_connected_to name: transitively proximally connected to namespace: uberon -def: "." [http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern] +property_value: seeAlso "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" xsd:anyURI is_transitive: true [Typedef] diff --git a/subsets/blood_and_immune_upper_slim.owl b/subsets/blood_and_immune_upper_slim.owl index 36e01f07d..d0c2dbd2b 100644 --- a/subsets/blood_and_immune_upper_slim.owl +++ b/subsets/blood_and_immune_upper_slim.owl @@ -18,6 +18,7 @@ xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#" xmlns:skos="http://www.w3.org/2004/02/skos/core#" xmlns:swrl="http://www.w3.org/2003/11/swrl#" + xmlns:sssom="https://w3id.org/sssom/" xmlns:swrla="http://swrl.stanford.edu/ontologies/3.3/swrla.owl#" xmlns:swrlb="http://www.w3.org/2003/11/swrlb#" xmlns:terms="http://purl.org/dc/terms/" @@ -29,8 +30,8 @@ xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#" xmlns:ncbitaxon="http://purl.obolibrary.org/obo/ncbitaxon#"> - - 2024-01-04 + + 2024-02-13 @@ -315,6 +316,14 @@ Annotations: IAO_0000424 "http://purl.obolibrary.org/obo/BFO_0000051 some ( + + + + + + + + @@ -337,6 +346,14 @@ Annotations: IAO_0000424 "http://purl.obolibrary.org/obo/BFO_0000051 some ( + + + + + + + + @@ -846,25 +863,25 @@ WHERE { - + - + - + - + - + - + @@ -1071,14 +1088,6 @@ WHERE { - - - - - - - - @@ -1103,14 +1112,6 @@ WHERE { - - - - - - - - @@ -1942,6 +1943,24 @@ WHERE { + + + + + + + + + + + + + + + + + + - - - - - - - - - - - - - - - - - - - - - A nucleus size quality which is relatively high compared to the amount of cytoplasm present in the same cell. - - 2009-12-23T10:53:24Z - increased nucleus size - - - - - A nucleus size quality which is relatively high compared to the amount of cytoplasm present in the same cell. - GOC:tfm - - - - @@ -16792,6 +16846,7 @@ For example, A and B may be gene products and binding of B by A positively regul 2014-02-11T17:29:04Z CL:2000001 + peripheral blood mononuclear cell @@ -19890,7 +19945,7 @@ For example, A and B may be gene products and binding of B by A positively regul - A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex). + A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex). https://github.com/geneontology/go-ontology/issues/17729 GO:0008372 NIF_Subcellular:sao1337158144 @@ -19911,7 +19966,7 @@ For example, A and B may be gene products and binding of B by A positively regul - A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex). + A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex). GOC:pdt @@ -19941,8 +19996,8 @@ For example, A and B may be gene products and binding of B by A positively regul + - Note that this term is intended to annotate gene products that are not attached to the cell surface. For gene products from multicellular organisms which are secreted from a cell but retained within the organism (i.e. released into the interstitial fluid or blood), consider the cellular component term 'extracellular space ; GO:0005615'. extracellular region @@ -19987,32 +20042,32 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + A protein complex consisting of three collagen chains assembled into a left-handed triple helix. These trimers typically assemble into higher order structures. Wikipedia:Collagen cellular_component GO:0005581 collagen trimer - + - + - + PMID:12382326 - + PMID:12382326 @@ -20094,7 +20149,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Note that for multicellular organisms, the extracellular space refers to everything outside a cell, but still within the organism (excluding the extracellular matrix). Gene products from a multi-cellular organism that are secreted from a cell into the interstitial fluid or blood can therefore be annotated to this term. extracellular space @@ -20234,8 +20289,8 @@ For example, A and B may be gene products and binding of B by A positively regul + - Chromosomes include parts that are not part of the chromatin. Examples include the kinetochore. chromosome @@ -20301,8 +20356,8 @@ For example, A and B may be gene products and binding of B by A positively regul + - cytoplasm @@ -20479,8 +20534,8 @@ For example, A and B may be gene products and binding of B by A positively regul + - ribosome @@ -20539,8 +20594,8 @@ For example, A and B may be gene products and binding of B by A positively regul + - plasma membrane @@ -20637,8 +20692,8 @@ For example, A and B may be gene products and binding of B by A positively regul + - DNA recombination @@ -20698,7 +20753,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + translation @@ -20826,7 +20881,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Note that this term should not be used for direct annotation. It should be possible to make a more specific annotation to one of the children of this term, for e.g. to transmembrane transport, to microtubule-based transport or to vesicle-mediated transport. transport @@ -21954,7 +22009,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -21970,7 +22025,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -22115,7 +22170,7 @@ For example, A and B may be gene products and binding of B by A positively regul necrosis GO:0008219 - This term should not be used for direct annotation, it is currently kept in GO as a placeholder for describing cell death phenotypes in uPHENO. When information is provided on a programmed cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'). Unintentional cell death, i.e. cell death caused by injury, ageing, or cell phenotypes observed as a result of a pathological mutation in an essential gene should NOT be annotated using GO terms. + This term should not be used for direct annotation, it is currently kept in GO as a placeholder for describing cell death phenotypes in uPHENO. When information is provided on a programmed cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'). Unintentional cell death, i.e. cell death caused by injury, ageing, or cell phenotypes observed as a result of a pathological mutation in an essential gene should NOT be annotated using GO terms. cell death @@ -22569,7 +22624,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Note that this term should be used to annotate gene products in the organism undergoing the programmed cell death. To annotate genes in another organism whose products modulate programmed cell death in a host organism, consider the term 'modulation by symbiont of host programmed cell death ; GO:0052040'. Also, note that 'programmed cell death ; GO:0012501' should be used to refer to instances of caspase-independent cell death mechanisms, in the absence of further indications on the process taking place. At present, caspase-independent cell death is not yet represented in GO due to the lack of consensus and in-depth research on the topic. 'programmed cell death ; GO:0012501' may also be used to annotate gene products in taxa where apoptosis as defined in GO:0006915 does not occur, such as plants. You may also consider these specific children: GO:0097468 'programmed cell death in response to reactive oxygen species' (with descendants GO:0010421 'hydrogen peroxide-mediated programmed cell death' and GO:0010343 'singlet oxygen-mediated programmed cell death'), and GO:0009626 'plant-type hypersensitive response' and its children. programmed cell death @@ -23617,8 +23672,8 @@ For example, A and B may be gene products and binding of B by A positively regul + - Note that a signal is any variable property or parameter that serves to convey information, and may be a physical entity such as a gene product or small molecule, a photon, or a change in state such as movement or voltage change. signaling @@ -23710,7 +23765,7 @@ For example, A and B may be gene products and binding of B by A positively regul cell projection organization and biogenesis cell surface structure organization and biogenesis GO:0030030 - + cell projection organization @@ -24731,7 +24786,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + extracellular matrix @@ -26450,7 +26505,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + cell projection @@ -26537,6 +26592,7 @@ For example, A and B may be gene products and binding of B by A positively regul The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. + https://github.com/geneontology/go-ontology/issues/26424 GO:0034960 GO:0043283 GO:0044259 @@ -26546,6 +26602,7 @@ For example, A and B may be gene products and binding of B by A positively regul multicellular organismal macromolecule metabolic process biological_process GO:0043170 + macromolecule metabolic process @@ -26595,7 +26652,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + organelle @@ -27019,9 +27076,11 @@ For example, A and B may be gene products and binding of B by A positively regul The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism. + https://github.com/geneontology/go-ontology/issues/26424 primary metabolism biological_process GO:0044238 + primary metabolic process @@ -27124,7 +27183,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. GO:0002226 Wikipedia:Innate_immune_system @@ -28268,9 +28327,11 @@ For example, A and B may be gene products and binding of B by A positively regul The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. + https://github.com/geneontology/go-ontology/issues/26424 development of an anatomical structure biological_process GO:0048856 + @@ -28318,7 +28379,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + cell motility @@ -28796,7 +28857,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. response to stimulus @@ -29336,7 +29397,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + molecular transducer activity @@ -29601,7 +29662,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + membrane organization @@ -29768,7 +29829,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + protein-containing complex assembly @@ -30048,6 +30109,7 @@ For example, A and B may be gene products and binding of B by A positively regul The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon. + https://github.com/geneontology/go-ontology/issues/26424 mah 2010-03-08T03:32:18Z organic molecular entity metabolic process @@ -30055,6 +30117,7 @@ For example, A and B may be gene products and binding of B by A positively regul organic substance metabolism biological_process GO:0071704 + organic substance metabolic process @@ -30298,7 +30361,7 @@ For example, A and B may be gene products and binding of B by A positively regul - The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures. + The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures. mah 2010-10-04T01:51:47Z cellular_component @@ -30309,7 +30372,7 @@ For example, A and B may be gene products and binding of B by A positively regul - The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures. + The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures. GOC:pdt @@ -30639,7 +30702,7 @@ For example, A and B may be gene products and binding of B by A positively regul biological_process GO:0098542 - + defense response to other organism @@ -31284,6 +31347,7 @@ For example, A and B may be gene products and binding of B by A positively regul A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex but below that of an anatomical system. Or, a substance produced by a cellular organism with granularity above the level of a protein complex. https://github.com/geneontology/go-ontology/issues/24200 + https://github.com/geneontology/go-ontology/issues/26424 kmv 2019-08-12T18:01:37Z cellular_component @@ -31571,6 +31635,27 @@ For example, A and B may be gene products and binding of B by A positively regul + + + + + Reactions triggered in response to the presence of a symbiont that act to protect or prevent damage to the host. + https://github.com/geneontology/go-ontology/issues/20261 + pg + 2020-11-11T17:19:06Z + biological_process + GO:0140546 + defense response to symbiont + + + + + Reactions triggered in response to the presence of a symbiont that act to protect or prevent damage to the host. + GOC:pg + + + + @@ -32880,57 +32965,6 @@ For example, A and B may be gene products and binding of B by A positively regul - - - - - quality - PATO:0000068 - TODO: define this or obsolete it and move children somewhere else. - qualitative - - - - - - - - - A quality inhering in a bearer by virtue of the whether the bearer differs from normal or average. - quality - PATO:0000069 - - deviation (from_normal) - - - - - A quality inhering in a bearer by virtue of the whether the bearer differs from normal or average. - PATOC:GVG - - - - - - - - - A morphology quality inhering in a bearer by virtue of the bearer's physical magnitude. - quality - PATO:0000117 - - - size - - - - - A morphology quality inhering in a bearer by virtue of the bearer's physical magnitude. - WordNet:WordNet - - - - @@ -33025,67 +33059,6 @@ For example, A and B may be gene products and binding of B by A positively regul - - - - - A quality inhering in a bearer by virtue of the bearer's exhibiting no deviation from normal or average. - - quality - average - PATO:0000461 - - - - normal - - - - - A quality inhering in a bearer by virtue of the bearer's exhibiting no deviation from normal or average. - PATOC:GVG - - - - - - - - - - - - - - - - - - - - - A size quality which is relatively high. - - PATO:0001202 - quality - big - enlarged - expanded - great - large - PATO:0000586 - - increased size - - - - - A size quality which is relatively high. - PATOC:GVG - - - - @@ -33861,77 +33834,6 @@ For example, A and B may be gene products and binding of B by A positively regul - - - - - - - - - - - - - - - - - - - - - - A quality that has a value that is increased compared to normal or average. - - - 2011-06-16T06:39:43Z - quality - PATO:0002300 - increased quality - - - - - A quality that has a value that is increased compared to normal or average. - PATOC:GVG - - - - - - - - - - - - - - - - - - - - - A quality of an object that has a value that is increased compared to normal or average. - - - 2011-06-16T06:54:01Z - quality - PATO:0002305 - increased object quality - - - - - A quality of an object that has a value that is increased compared to normal or average. - PATOC:GVG - - - - @@ -34040,6 +33942,28 @@ For example, A and B may be gene products and binding of B by A positively regul + + + + + A quality inhering in a cell by virtue of the cell having a high nuclear/cytoplasmic ratio. + http://orcid.org/0000-0001-5208-3432 + high N:C ratio + quality + PATO:0040072 + A high nuclear/cytolasmic ratio is 70% or higher. + high nuclear/cytoplasmic ratio + + + + + A quality inhering in a cell by virtue of the cell having a high nuclear/cytoplasmic ratio. + Wikipedia:NC_ratio&oldid=931936284 + http://lymerick.net/blood-cells.pdf + + + + @@ -37533,6 +37457,12 @@ For example, A and B may be gene products and binding of B by A positively regul Material anatomical entity that is a single connected structure with inherent 3D shape generated by coordinated expression of the organism's own genome. CARO:0000003 + + + + FBbt:00007001 + + @@ -38084,7 +38014,9 @@ For example, A and B may be gene products and binding of B by A positively regul IDOMAL:0000302 - https://orcid.org/0000-0003-4423-4370 + + + https://github.com/biopragmatics/biomappings @@ -38109,7 +38041,7 @@ For example, A and B may be gene products and binding of B by A positively regul zygotum Wikipedia:Zygote - + @@ -38233,7 +38165,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -38269,14 +38201,14 @@ For example, A and B may be gene products and binding of B by A positively regul gastrula stage - + - + BILS @@ -38554,6 +38486,12 @@ For example, A and B may be gene products and binding of B by A positively regul in FMA, the tongue, palate etc are part of the mouth which is itself a subdivision of the face. ZFA includes a separate class 'oral region' which is part of the mouth, but excludes tongue and lips FMA + + + + FBbt:00003126 + + @@ -38561,14 +38499,14 @@ For example, A and B may be gene products and binding of B by A positively regul BTO:0004698 FMA:49184 FMA:TA - + cavital oralis Wikipedia:Mouth - + @@ -38644,15 +38582,15 @@ For example, A and B may be gene products and binding of B by A positively regul - + - - + + A fluid that is composed of blood plasma and erythrocytes. This class excludes blood analogues, such as the insect analog of blood. See UBERON:0000179 haemolymphatic fluid. @@ -38694,34 +38632,34 @@ For example, A and B may be gene products and binding of B by A positively regul blood - + - + - + - + CL:tm - + https://github.com/obophenotype/uberon/issues/1330 - + Bgee:AN @@ -39025,7 +38963,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -39067,14 +39005,14 @@ For example, A and B may be gene products and binding of B by A positively regul organism substance - + - + this relationship may be too strong and may be weakened in future @@ -39083,6 +39021,12 @@ For example, A and B may be gene products and binding of B by A positively regul Material anatomical entity in a gaseous, liquid, semisolid or solid state; produced by anatomical structures or derived from inhaled and ingested substances that have been modified by anatomical structures as they pass through the body. http://orcid.org/0000-0001-9114-8737 + + + + FBbt:00007019 + + @@ -39161,6 +39105,12 @@ For example, A and B may be gene products and binding of B by A positively regul Non-material anatomical entity of three dimensions, that is generated by morphogenetic or other physiologic processes; is surrounded by one or more anatomical structures; contains one or more organism substances or anatomical structures. http://orcid.org/0000-0001-9114-8737 + + + + FBbt:00007017 + + @@ -39210,6 +39160,12 @@ For example, A and B may be gene products and binding of B by A positively regul Anatomical entity that has mass. http://orcid.org/0000-0001-9114-8737 + + + + FBbt:00007016 + + @@ -39246,6 +39202,12 @@ For example, A and B may be gene products and binding of B by A positively regul Anatomical entity that has no mass. http://orcid.org/0000-0001-9114-8737 + + + + FBbt:00007015 + + @@ -39331,11 +39293,19 @@ For example, A and B may be gene products and binding of B by A positively regul system GO:0048731 + + + + FBbt:00004856 + + IDOMAL:0002460 - https://orcid.org/0000-0003-4423-4370 + + + https://github.com/biopragmatics/biomappings @@ -39434,6 +39404,12 @@ For example, A and B may be gene products and binding of B by A positively regul VHOG:0000671 WBbt:0007833 + + + + FBbt:00000001 + + @@ -39537,6 +39513,12 @@ For example, A and B may be gene products and binding of B by A positively regul CARO:DOS http://orcid.org/0000-0001-9114-8737 + + + + FBbt:00007009 + + @@ -39604,6 +39586,12 @@ For example, A and B may be gene products and binding of B by A positively regul Anatomical structure that consists of cell parts and cell substances and together does not constitute a cell or a tissue. http://orcid.org/0000-0001-9114-8737 + + + + FBbt:00007013 + + @@ -39623,7 +39611,6 @@ For example, A and B may be gene products and binding of B by A positively regul FBbt:00007277 - IDOMAL:0002461 VHOG:0001737 uberon UBERON:0000477 @@ -39640,8 +39627,8 @@ For example, A and B may be gene products and binding of B by A positively regul - IDOMAL:0002461 - https://orcid.org/0000-0003-4423-4370 + FBbt:00007277 + @@ -39712,6 +39699,12 @@ For example, A and B may be gene products and binding of B by A positively regul Multicellular anatomical structure that consists of many cells of one or a few types, arranged in an extracellular matrix such that their long-range organisation is at least partly a repetition of their short-range organisation. CARO:0000043 + + + + FBbt:00007003 + + @@ -39779,6 +39772,12 @@ For example, A and B may be gene products and binding of B by A positively regul CARO:0000055 http://orcid.org/0000-0001-9114-8737 + + + + FBbt:00007010 + + @@ -39817,7 +39816,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -39861,14 +39860,14 @@ For example, A and B may be gene products and binding of B by A positively regul epithelium https://upload.wikimedia.org/wikipedia/commons/8/8f/Illu_epithelium.jpg - + - + http://palaeos.com/metazoa/porifera/homoscleromorpha.html @@ -39888,6 +39887,12 @@ For example, A and B may be gene products and binding of B by A positively regul ISBN:978-0030259821 Ruppert EE, Fox RS, Barnes RD, Invertebrate zoology: a functional evolutionary approach (2003) p.59 http://bgee.unil.ch/ + + + + FBbt:00007005 + + @@ -40203,11 +40208,19 @@ For example, A and B may be gene products and binding of B by A positively regul Obsoleted in ZFA. Note that embryo is not classified as an embryonic structure - an embryonic structure is only the parts of an embryo ZFA + + + + FBbt:00000052 + + IDOMAL:0000646 - https://orcid.org/0000-0003-4423-4370 + + + https://github.com/biopragmatics/biomappings @@ -40294,6 +40307,12 @@ For example, A and B may be gene products and binding of B by A positively regul embryonic tissue FMA:69069 + + + + FBbt:00000110 + + @@ -40332,7 +40351,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Primary germ layer that is the outer of the embryo's three germ layers and gives rise to epidermis and neural tissue. Primary germ layer that is the outer of the embryonic germ layers and gives rise to epidermis and neural tissue.[AAO] The Bilateria are triploblastic (with true endoderm, mesoderm, and ectoderm) (...).[well established][VHOG] @@ -40370,14 +40389,14 @@ For example, A and B may be gene products and binding of B by A positively regul ectoderm http://upload.wikimedia.org/wikipedia/commons/1/19/Gray32.png - + - + Bgee:AN @@ -40405,6 +40424,12 @@ For example, A and B may be gene products and binding of B by A positively regul ISBN:978-0878932504 Gilbert SF, Developmental Biology (2006) Limb development and evolution, p.722 http://bgee.unil.ch/ + + + + FBbt:00000111 + + @@ -40430,7 +40455,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Primary germ layer that lies remote from the surface of the embryo and gives rise to internal tissues such as gut. The Bilateria are triploblastic (with true endoderm, mesoderm, and ectoderm) (...).[well established][VHOG] endodermal @@ -40467,14 +40492,14 @@ For example, A and B may be gene products and binding of B by A positively regul http://upload.wikimedia.org/wikipedia/commons/c/c0/Endoderm2.png http://upload.wikimedia.org/wikipedia/commons/d/df/Gray10.png - + - + Bgee:AN @@ -40493,6 +40518,12 @@ For example, A and B may be gene products and binding of B by A positively regul ISBN:978-0878932504 Gilbert SF, Developmental Biology (2006) Limb development and evolution, p.722 http://bgee.unil.ch/ + + + + FBbt:00000125 + + @@ -40519,7 +40550,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + The middle germ layer of the embryo, between the endoderm and ectoderm. Primary germ layer that is the middle of the embryonic germ layers.[AAO] @@ -40564,7 +40595,7 @@ For example, A and B may be gene products and binding of B by A positively regul mesoderm http://upload.wikimedia.org/wikipedia/commons/e/e8/Mesoderm.png - + @@ -40577,7 +40608,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Bgee:AN @@ -40611,6 +40642,12 @@ For example, A and B may be gene products and binding of B by A positively regul sponges do not seem to have a mesoderm and accordingly Amphimedon lacks transcription factors involved in mesoderm development (Fkh, Gsc, Twist, Snail)[http://www.nature.com/nature/journal/v466/n7307/full/nature09201.html]. Mesoderm may not be homologous across verteberates https://github.com/obophenotype/uberon/wiki/The-neural-crest + + + + FBbt:00000126 + + @@ -40720,6 +40757,12 @@ For example, A and B may be gene products and binding of B by A positively regul stomodeal-hypophyseal primordium XAO:0000269 + + + + FBbt:00000439 + + @@ -40784,7 +40827,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -40861,14 +40904,14 @@ For example, A and B may be gene products and binding of B by A positively regul https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Heart.glb https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Heart.glb - + - + MA @@ -41154,6 +41197,12 @@ For example, A and B may be gene products and binding of B by A positively regul many anatomy ontologies consider gastrointestinal system synonymous with digestive system. here we follow MA in dividing digestive system into gastrointestinal and hepatobiliary. hepatobiliary includes the liver and biliary tract. species-specific AO classes are categorized according to whether liver is included. For example, XAO includes liver as part of XAO:0000125 alimentary system, so we assume this class is the more generic class MA + + + + FBbt:00005055 + + @@ -41195,6 +41244,7 @@ For example, A and B may be gene products and binding of B by A positively regul We should divest ourselves of the view that earlier vertebrate groups were 'on their way' to becoming mammals, as clearly they were not such visionaries. Neither were their systems 'imperfect' as earlier anatomists thought. Instead, their circulatory systems served them well to address the ecological demands arising from their lifestyles.[well established][VHOG] AAO:0000959 CALOHA:TS-2103 + MESH:D002319 VHOG:0001248 Wikipedia:Circulatory_system uberon @@ -41242,12 +41292,19 @@ For example, A and B may be gene products and binding of B by A positively regul ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.493 http://bgee.unil.ch/ + + + + MESH:D002319 + + https://github.com/biopragmatics/biomappings + systema cardiovasculare Wikipedia:Circulatory_system - + @@ -41328,7 +41385,7 @@ For example, A and B may be gene products and binding of B by A positively regul musculi FMA:32558 FMA:TA - + @@ -41379,13 +41436,14 @@ For example, A and B may be gene products and binding of B by A positively regul - + The nervous system is an organ system containing predominantly neuron and glial cells. In bilaterally symmetrical organism, it is arranged in a network of tree-like structures connected to a central body. The main functions of the nervous system are to regulate and control body functions, and to receive sensory input, process this information, and generate behavior [CUMBO]. + A regulatory system of the body that consists of neurons and neuroglial cells. The nervous system is divided into two parts, the central nervous system (CNS) and the peripheral nervous system (PNS). (Source: BioGlossary, www.Biology-Text.com)[TAO] Anatomical system consisting of nerve bodies and nerve fibers which regulate the response of the body to external and internal stimuli.[AAO] Nervous systems evolved in the ancestor of Eumetazoa.[well established][VHOG] @@ -41425,6 +41483,7 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0001016 + @@ -41432,14 +41491,14 @@ For example, A and B may be gene products and binding of B by A positively regul http://upload.wikimedia.org/wikipedia/commons/b/b2/TE-Nervous_system_diagram.svg http://upload.wikimedia.org/wikipedia/commons/b/ba/Nervous_system_diagram.png - + - + Bgee:AN @@ -41482,6 +41541,12 @@ For example, A and B may be gene products and binding of B by A positively regul ISBN:978-0198566694 Schmidt-Rhaesa A, The evolution of organ systems (2007) p.117 http://bgee.unil.ch/ + + + + FBbt:00005093 + + @@ -41505,7 +41570,7 @@ For example, A and B may be gene products and binding of B by A positively regul systema nervosum Wikipedia:Nervous_system - + @@ -41527,9 +41592,10 @@ For example, A and B may be gene products and binding of B by A positively regul - + The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the neural tube derivatives: the brain and spinal cord. In invertebrates it includes central ganglia plus nerve cord. + Part of the nervous system which includes the brain and spinal cord.[AAO] The brain and spinal cord. Kimmel et al, 1995.[TAO] The central nervous system (CNS) is the part of the nervous system which includes the brain, spinal cord, and nerve cell layer of the retina (CUMBO). @@ -41569,12 +41635,13 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0001017 + central nervous system - + @@ -41588,7 +41655,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Bgee:AN @@ -41639,6 +41706,12 @@ For example, A and B may be gene products and binding of B by A positively regul ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.28 (reference 1), ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.165 (reference 2), DOI:10.1016/j.cell.2007.02.040 Denes AS, Jekely G, Steinmetz PRH, Raible F, Snyman H, Prud'homme B, Ferrier DEK, Balavoine G and Arendt D, Molecular architecture of annelid nerve cord supports common origin of nervous system centralization in Bilateria. Cell (2007) (reference 3) http://bgee.unil.ch/ + + + + FBbt:00005094 + + @@ -41658,7 +41731,7 @@ For example, A and B may be gene products and binding of B by A positively regul systema nervosum centrale FMA:55675 FMA:TA - + @@ -41724,6 +41797,12 @@ For example, A and B may be gene products and binding of B by A positively regul FB:FBrf0089570 http://flybase.org/reports/FBrf0178740.html + + + + FBbt:00005495 + + @@ -41844,6 +41923,14 @@ For example, A and B may be gene products and binding of B by A positively regul The mature structure of the neural tube exists when the tube has been segmented into the forebrain, midbrain, hindbrain and spinal cord regions. In addition neural crest has budded away from the epithelium GO:0021915 + + + + MESH:D054259 + + + https://github.com/biopragmatics/biomappings + @@ -41855,7 +41942,7 @@ For example, A and B may be gene products and binding of B by A positively regul tubus neuralis Wikipedia:Neural_tube - + @@ -41898,6 +41985,12 @@ For example, A and B may be gene products and binding of B by A positively regul FMA:62955 http://orcid.org/0000-0001-9114-8737 + + + + FBbt:10000000 + + @@ -42272,6 +42365,7 @@ For example, A and B may be gene products and binding of B by A positively regul FBbt:00003125 FMA:45615 MA:0000917 + MESH:D041981 NCIT:C34082 TAO:0000112 TGMA:0001819 @@ -42353,6 +42447,19 @@ For example, A and B may be gene products and binding of B by A positively regul we place the MA and EMAPA class here, although the intent is probably a smaller region. See https://github.com/obophenotype/uberon/issues/509 MA + + + + FBbt:00003125 + + + + + + MESH:D041981 + + https://github.com/biopragmatics/biomappings + @@ -42577,8 +42684,8 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -42591,7 +42698,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -42650,34 +42757,34 @@ For example, A and B may be gene products and binding of B by A positively regul blood vessel http://upload.wikimedia.org/wikipedia/commons/2/29/Circulatory_System_en.svg - + - + - + - + AEO - + EHDAA2 - + GO:0072360 @@ -42750,7 +42857,7 @@ For example, A and B may be gene products and binding of B by A positively regul vas sanguineum Wikipedia:Blood_vessel - + @@ -42984,6 +43091,12 @@ For example, A and B may be gene products and binding of B by A positively regul in FMA embryo is_a embryonic structure FMA + + + + FBbt:00004208 + + @@ -43161,6 +43274,7 @@ For example, A and B may be gene products and binding of B by A positively regul FMA:71221 MA:0002986 MAT:0000148 + MESH:D013131 MIAA:0000148 TAO:0000317 VHOG:0000317 @@ -43236,6 +43350,13 @@ For example, A and B may be gene products and binding of B by A positively regul EMAPA:37721 MA:th + + + + MESH:D013131 + + https://github.com/biopragmatics/biomappings + @@ -43400,7 +43521,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -43434,14 +43555,14 @@ For example, A and B may be gene products and binding of B by A positively regul musculoskeletal system - + - + check ctenophore @@ -43555,7 +43676,7 @@ For example, A and B may be gene products and binding of B by A positively regul cavitas thoracis Wikipedia:Thoracic_cavity - + @@ -43570,7 +43691,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -43611,14 +43732,14 @@ For example, A and B may be gene products and binding of B by A positively regul EDITOR_NOTE check the FMA placement here; ncit placement of body cavity here probably not correct coelemic cavity lumen - + - + definitional @@ -43651,6 +43772,12 @@ For example, A and B may be gene products and binding of B by A positively regul body cavity BTO:0001707 + + + + FBbt:00005060 + + @@ -43726,9 +43853,9 @@ For example, A and B may be gene products and binding of B by A positively regul - - - + + + @@ -43783,15 +43910,15 @@ For example, A and B may be gene products and binding of B by A positively regul notochord http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + - + - + @@ -43810,19 +43937,19 @@ For example, A and B may be gene products and binding of B by A positively regul - + http://tolweb.org/Chordata/2499 - + ZFA - + EHDAA2 @@ -43897,7 +44024,7 @@ For example, A and B may be gene products and binding of B by A positively regul notochorda Wikipedia:Notochord - + @@ -43907,8 +44034,8 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + Somites are spheres of epithelial cells that form sequentially along the anterior-posterior axis of the embryo through mesenchymal to epithelial transition of the presomitic mesoderm. EDITOR_NOTE currently classified as an epithelial vesicle, consistent with EHDAA2 and https://github.com/obophenotype/uberon/wiki/The-neural-crest. Consider making 'somitic mesoderm' a separate term and correlate with regionalization processes. Consider moving ZFA term to 'trunk somite' as it is part of the trunk @@ -43954,11 +44081,11 @@ For example, A and B may be gene products and binding of B by A positively regul somite http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + - + @@ -43971,13 +44098,13 @@ For example, A and B may be gene products and binding of B by A positively regul - + GOTAX:0000352 - + ZFA @@ -44080,7 +44207,7 @@ For example, A and B may be gene products and binding of B by A positively regul somitus Wikipedia:Somite - + @@ -44090,12 +44217,12 @@ For example, A and B may be gene products and binding of B by A positively regul - - - - - - + + + + + + A specialized region of ectoderm found between the neural ectoderm (neural plate) and non-neural ectoderm and composed of highly migratory pluripotent cells that delaminate in early embryonic development from the dorsal neural tube and give rise to an astounding variety of differentiated cell types[MP]. EDITOR_NOTE consider including subclasses for pre- and post- migratory (e.g. sheets/paths/streams). @@ -44135,66 +44262,66 @@ For example, A and B may be gene products and binding of B by A positively regul http://upload.wikimedia.org/wikipedia/commons/5/5f/Gray644.png https://upload.wikimedia.org/wikipedia/commons/8/8f/Neural_Crest.png - + - + - + - + - + - + - + XAO https://github.com/obophenotype/uberon/wiki/The-neural-crest - + Hall and others restrict NC to vertebrates but we opt for a less restrictive constraint to avoid inconsistencies when areas such as P1 area of pallium in hagfishes inherit cell lineage from telecephalon-contributing NC cells ISBN:0073040584 - + BTO - + PMID:11523831 - + pre migratory https://github.com/obophenotype/uberon/wiki/The-neural-crest - + PMID:11523831 @@ -44262,7 +44389,7 @@ For example, A and B may be gene products and binding of B by A positively regul crista neuralis Wikipedia:Neural_crest - + @@ -44335,6 +44462,12 @@ For example, A and B may be gene products and binding of B by A positively regul DOI:10.1046/j.1469-7580.2001.19910133.x Graham A. The development and evolution of the pharyngeal arches. J Anat (2001) http://bgee.unil.ch/ + + + + FBbt:00001057 + + @@ -44346,7 +44479,7 @@ For example, A and B may be gene products and binding of B by A positively regul epithelium tubi neuralis; neuroectoderma Wikipedia:Neuroectoderm - + @@ -44382,7 +44515,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -44440,14 +44573,14 @@ For example, A and B may be gene products and binding of B by A positively regul bone marrow http://upload.wikimedia.org/wikipedia/commons/7/74/Gray72-en.svg - + - + FMA MA @@ -44480,7 +44613,7 @@ For example, A and B may be gene products and binding of B by A positively regul medulla ossea BTO:0000141 FMA:9608 - + @@ -44488,7 +44621,7 @@ For example, A and B may be gene products and binding of B by A positively regul medulla ossium BTO:0000141 Wikipedia:Bone_marrow - + @@ -44718,14 +44851,14 @@ For example, A and B may be gene products and binding of B by A positively regul - + - + Anatomical system that is involved in the production of hematopoietic cells. @@ -44770,24 +44903,24 @@ For example, A and B may be gene products and binding of B by A positively regul hematopoietic system - + - + - + FMA - + definitional @@ -45078,7 +45211,7 @@ For example, A and B may be gene products and binding of B by A positively regul epiblastus Wikipedia:Epiblast - + @@ -45158,7 +45291,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Unsegmented field of paraxial mesoderm present posterior to the most recently formed somite pair, from which somites will form. Unsegmented field of paraxial mesoderm present posterior to the most recently formed somite pair, from which somites will form. Kimmel et al, 1995.[TAO] It is reasonable to assume that the proximate invertebrate ancestor of the vertebrates had an amphioxus-like tail bud in its larval stage. This archetypal tail bud would have (...) (3) lacked any component of mesenchyme cells, (4) budded off new mesodermal segments directly, without any intervening zone of presomitic mesoderm (...). Then, early in vertebrate evolution, epithelium-to-mesenchyme interconversions (and the gene networks for effecting them) became prominent features of development. (...) In any case, conspicuous mesenchymal components tended to be added to the vertebrate tail bud itself. In addition, a mesenchymatous presomitic mesoderm (not a part of the tail bud proper) came to intervene between the tail bud and the forming somites.[well established][VHOG] @@ -45183,14 +45316,14 @@ For example, A and B may be gene products and binding of B by A positively regul presomitic mesoderm - + - + Bgee:AN @@ -45420,9 +45553,9 @@ For example, A and B may be gene products and binding of B by A positively regul - - - + + + A region of embryonic ectodermal cells that lie directly above the notochord. During neurulation, they change shape and produce an infolding of the neural plate (the neural fold) that then seals to form the neural tube[XAO]. The earliest recognizable dorsal ectodermal primordium of the central nervous system present near the end of gastrulation before infolding to form the neural keel; consists of a thickened pseudostratified epithelium[ZFA]. The earliest recognizable dorsal ectodermal primordium of the central nervous system present near the end of gastrulation before infolding to form the neural keel; consists of a thickened pseudostratified epithelium. Kimmel et al, 1995.[TAO] (...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord that is located dorsal to the notochord (...).[well established][VHOG] @@ -45454,34 +45587,34 @@ For example, A and B may be gene products and binding of B by A positively regul neural plate https://upload.wikimedia.org/wikipedia/commons/8/8f/Neural_Crest.png - + - + - + - + GOTAX:0000352 - + Wikipedia - + Bgee:AN @@ -45512,6 +45645,14 @@ For example, A and B may be gene products and binding of B by A positively regul ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.28 http://bgee.unil.ch/ + + + + MESH:D054258 + + + https://github.com/biopragmatics/biomappings + @@ -45523,7 +45664,7 @@ For example, A and B may be gene products and binding of B by A positively regul lamina neuralis Wikipedia:Neural_plate - + @@ -45546,7 +45687,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube[GO]. Mesoderm lateral to the neural tube and notochord that is divided into cranial and post-cranial portions. The trunk portions further segment into somites.[AAO] Presently, Cephalochordata, Urochordata, and Vertebrata are placed as subphyla of the phylum Chordata, in which the overall organization of embryonic tissues (dorsal hollow nerve cord, ventral digestive tract, axial notochord, and bilateral paraxial mesoderm) is largely conserved. In contrast, the echinoderms and hemichordates are sister groups of the chordates and they lack the notochord and paraxial mesoderm. Thus, the basic mesodermal organization of vertebrates must have appeared first in the common ancestor of the chordates.[well established][VHOG] @@ -45575,7 +45716,7 @@ For example, A and B may be gene products and binding of B by A positively regul paraxial mesoderm http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + @@ -45588,7 +45729,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Bgee:AN @@ -45648,7 +45789,7 @@ For example, A and B may be gene products and binding of B by A positively regul mesoderma paraxiale Wikipedia:Paraxial_mesoderm - + @@ -45660,7 +45801,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -45704,7 +45845,7 @@ For example, A and B may be gene products and binding of B by A positively regul lateral plate mesoderm http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + @@ -45717,7 +45858,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + EHDAA2 VHOG @@ -45792,7 +45933,7 @@ For example, A and B may be gene products and binding of B by A positively regul mesoderma laminae lateralis Wikipedia:Lateral_plate_mesoderm - + @@ -45801,15 +45942,15 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + - + Bilateral groups of cells consisting of three rows: one row of endocardial precursors medially and two rows of myocardical precursors laterally. The two populations fuse at the midline to form the heart rudiment or cone. should probably be merged with heart rudiment. Bilateral groups of cells consisting of three rows: one row of endocardial precursors medially and two rows of myocardical precursors laterally. The two populations fuse at the midline between 21 and 26 somites to form the heart rudiment or cone. Stainier 2001.[TAO] @@ -45829,15 +45970,15 @@ For example, A and B may be gene products and binding of B by A positively regul heart primordium - + - + - + @@ -45850,19 +45991,19 @@ For example, A and B may be gene products and binding of B by A positively regul - + ZFA - + ZFA - + XAO @@ -45917,8 +46058,8 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + Ventral somitic compartment that is a precursor of the axial skeleton[XAO]. Sclerotomes eventually differentiate into the vertebrae and most of the skull. The caudal (posterior) half of one sclerotome fuses with the rostral (anterior) half of the adjacent one to form each vertebra. From their initial location within the somite, the sclerotome cells migrate medially towards the notochord. These cells meet the sclerotome cells from the other side to form the vertebral body. From this vertebral body, sclerotome cells move dorsally and surround the developing spinal cord, forming the vertebral arch[WP]. Skeletogenic portion of somites.[AAO] The vertebrate sclerotome has no equivalent in amphioxus and is a novelty linked with the evolution of the axial skeleton.[well established][VHOG] @@ -45946,11 +46087,11 @@ For example, A and B may be gene products and binding of B by A positively regul sclerotome http://upload.wikimedia.org/wikipedia/commons/9/96/Gray65.png - + - + @@ -45969,13 +46110,13 @@ For example, A and B may be gene products and binding of B by A positively regul - + VHOG:0000680 - + ZFA @@ -46015,7 +46156,9 @@ For example, A and B may be gene products and binding of B by A positively regul BTO:0006255 - https://orcid.org/0000-0003-4423-4370 + + + https://github.com/biopragmatics/biomappings @@ -46035,7 +46178,7 @@ For example, A and B may be gene products and binding of B by A positively regul sclerotomus Wikipedia:Sclerotome - + @@ -46175,7 +46318,7 @@ For example, A and B may be gene products and binding of B by A positively regul mesenchyma Wikipedia:Mesenchyme - + @@ -46247,7 +46390,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + The part of the coelom in the embryo between the somatopleuric and splanchnopleuric mesoderm; the principal body cavities of the trunk (thoracic, abdominal, and pelvic) arise from this embryonic part of the coelom. consider merging with coelom. TODO - add spatial relationships to halves of LPM. Note the OG places XAO and ZFA coelem terms here. editor note: TODO check ZFA, which appears to be a structure present in adults (...) I regard it unlikely that coeloms of all bilaterian animals are comparable and evolved very early. Considering all these questions, few convincing characters concerning the evolution of body cavities remain to be named. (...) A segmental coelom appears to have evolved at least two times, in Annelida and in Myomerata (Acrania and Craniota).[well established][VHOG] @@ -46263,14 +46406,14 @@ For example, A and B may be gene products and binding of B by A positively regul intraembryonic coelom - + - + Wikipedia @@ -46338,6 +46481,12 @@ For example, A and B may be gene products and binding of B by A positively regul GO:0060562 PMID:12526790 + + + + FBbt:00007474 + + @@ -46589,8 +46738,8 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + A specific region of the lateral mesoderm that will form the primary beating heart tube. In mammals the primary heart field gives rise to the left ventricle. this term denotes the primary heart field; GO:0003128 denotes the superclass of primary and secondary: specific region of the lateral mesoderm into the area which will form the primary beating heart tube[GO:0003138] XAO:0004185 @@ -46603,24 +46752,24 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0004140 primary heart field - + - + - + GO:0003128 - + https://orcid.org/0000-0003-3308-6245 @@ -46679,7 +46828,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + An epithelial tube that will give rise to the mature heart. the paired, longitudinal, endothelial-lined channels formed from the cardiogenic mesoderm in embryonic development; angiogenic cell clusters (aka angioblastic cords) located in a horse-shoe shape configuration in the cardiogenic plate coalesce to form the right and left endocardial heart tubes which then fuse in cephalo-caudal direction to form a single primitive heart tube. AAO:0010411 @@ -46699,14 +46848,14 @@ For example, A and B may be gene products and binding of B by A positively regul heart tube - + - + ZFA-modified @@ -47082,6 +47231,7 @@ For example, A and B may be gene products and binding of B by A positively regul An endothelium that lines the blood vasculature. Other endothelia may line lymph vessels, the heart. + BTO:0000766 CALOHA:TS-2155 EMAPA:35176 @@ -47092,6 +47242,7 @@ For example, A and B may be gene products and binding of B by A positively regul ZFA:0005257 uberon UBERON:0004638 + blood vessel endothelium @@ -47246,6 +47397,12 @@ For example, A and B may be gene products and binding of B by A positively regul We explicitly merge the NCITA terms here NCIT + + + + FBbt:00005317 + + @@ -47325,7 +47482,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + A specialized form of connective tissue in which the extracellular matrix is firm, providing the tissue with resilience, and/or mineralized and that functions in mechanical and structural support.[VSAO]. A specialized form of connective tissue in which the extracellular matrix is firm, providing the tissue with resilience, and/or mineralized and that functions in mechanical and structural support.[VSAO] EMAPA:37744 @@ -47339,7 +47496,7 @@ For example, A and B may be gene products and binding of B by A positively regul Four classes of mineralized tissues are found in vertebrates: bone, cartilage, dentine, and enamel. We think of cartilage and bone as skeletal tissues and of enamel and dentine as dental tissues, but enamel and dentine arose evolutionarily together with bone as skeletal tissues in the dermal skeleton (exoskeleton) of early vertebrates. Scales and teeth of sharks are examples of dermal skeletal elements that are still composed of the three ancient components-enamel, dentine, and bone. Cartilage, on the other hand, provided the basis for the second vertebrate skeletal system, the endoskeleton (Smith and Hall, 1990; Hall, 1998a,b). some invertebrate skeletal tissues have surprisingly bone-like features. Examples include chondrocytes interconnected by cell processes in cephalopod cartilages (Cole and Hall, 2004a,b), and the calcium phosphate layer in the shells of brachiopods (Rodland et al., 2003). However, neither bone nor mineralized cartilage have been found in invertebrates. Editors notes: TODO - develops_from skeletal tissue - + @@ -47352,7 +47509,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + 2012-08-14 VSAO:0000015 VSAO @@ -47391,7 +47548,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Organ consisting of skeletal tissue. Encompasses whole bones, fused bones, cartilaginious elements, teeth, dermal denticles. Organ entity that is typically involved in mechanical support and may have different skeletal tissue compositions at different stages.[VSAO] Organ entity that may have different tissue compositions at different stages and is typically involved in mechanical support.[TAO] @@ -47407,14 +47564,14 @@ For example, A and B may be gene products and binding of B by A positively regul skeletal element - + - + VSAO @@ -47459,7 +47616,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -47498,14 +47655,14 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0004770 articular system - + - + FMA @@ -47760,6 +47917,12 @@ For example, A and B may be gene products and binding of B by A positively regul Anatomical structure that connects two or more adjacent skeletal elements or hardened body parts. http://orcid.org/0000-0002-6601-2165 + + + + FBbt:00005811 + + @@ -47812,6 +47975,12 @@ For example, A and B may be gene products and binding of B by A positively regul A proximal-distal subdivision of the digestive tract. http://orcid.org/0000-0002-6601-2165 + + + + FBbt:00100315 + + @@ -48265,7 +48434,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Mesenchyme that is part of a developing trunk. EFO:0003485 EHDAA2:0002092 @@ -48281,14 +48450,14 @@ For example, A and B may be gene products and binding of B by A positively regul trunk mesenchyme - + - + EHDAA2 @@ -48379,6 +48548,12 @@ For example, A and B may be gene products and binding of B by A positively regul developing anatomical structure + + + + FBbt:00007006 + + @@ -48399,7 +48574,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Multi-tissue structure that arises from the heart rudiment and will become the heart tube. BTO:0006179 EHDAA2:0001512 @@ -48418,14 +48593,14 @@ For example, A and B may be gene products and binding of B by A positively regul primitive heart tube - + - + ZFA @@ -48438,7 +48613,9 @@ For example, A and B may be gene products and binding of B by A positively regul BTO:0006179 - https://orcid.org/0000-0003-4423-4370 + + + https://github.com/biopragmatics/biomappings @@ -48583,7 +48760,7 @@ For example, A and B may be gene products and binding of B by A positively regul membrana basalis Wikipedia:Basement_membrane - + @@ -48599,7 +48776,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + A delimited region of dense mesenchyme within looser mesenchyme. AEO:0000148 EHDAA2_RETIRED:0003148 @@ -48609,7 +48786,7 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0005856 developing mesenchymal condensation - + @@ -48628,7 +48805,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + AEO-modified-relation @@ -48721,7 +48898,7 @@ For example, A and B may be gene products and binding of B by A positively regul skeleton axiale Wikipedia:Axial_skeleton - + @@ -48733,7 +48910,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + The notochordal plate is the dorsal part of the notochordal process when the ventral portion breaks down. It is continuous laterally with the endoderm that composes the roof of the primitive foregut and is in contact dorsally with the neural tube. The folding off of the notochordal plate gives rise to the notochord. TODO - check ordering; awaiting confirmation from JB The notochordal plate is the dorsal part of the notochordal process when the ventral portion breaks down. It is continuous laterally with the endoderm that composes the roof of the primitive foregut and is in contact dorsally with the neural tube. The folding off of the notochordal plate gives rise to the notochord. [Carson_JL, Dehart_DB, Developmental_Dynamics_(1994)_201:_260-278, Gesteland_K_and_Schoenwolf_GC, Inagaki_T, Morphogenesis_of_the_murine_node_and_notochordal_plate, The_prechordal_plate, Vrablic_T, see_Mueller_F_and_O'Rahilly_R, the_rostral_end_of_the_notochord_and_nearby_median_features_in_staged_human_embryos._Cells_Tissues_Organs_(2003)_173:_1-20_and_Sulik_K][VHOG] @@ -48748,7 +48925,7 @@ For example, A and B may be gene products and binding of B by A positively regul notochordal plate - + @@ -48761,7 +48938,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + EHDAA2 @@ -48798,7 +48975,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + A midline cellular cord formed from the migration of mesenchymal cells from the primitive knot. EHDAA2:0001279 EHDAA:224 @@ -48815,14 +48992,14 @@ For example, A and B may be gene products and binding of B by A positively regul The notochordal process grows cranially until it reaches the prechordal plate, the future site of the mouth. In this area the ectoderm is attached directly to the endoderm without intervening mesoderm. This area is known as the oropharyngeal membrane, and it will break down to become the mouth. At the other end of the primitive streak the ectoderm is also fused directly to the endoderm; this is known as the cloacal membrane (proctodeum), or primordial anus. notochordal process - + - + EHDAA2 @@ -49529,7 +49706,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + A hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood or analogs[GO,modified]. note we reserve the subclass 'heart' from the vertebrate multi-chambered heart. 'The first heart-like organ is believed to have appeared 500my ago in an ancestral bilaterian'. Amniotes: four-chambered heart. Amphibians: two atria, one ventricle, pulmonary; fish: single atrium and ventricle; amphioxus: tubular, non-striated, closed, unidirectional; ascidians: tubular, striated, open, bidirectional; arthropods: tubular, open; C elegans: contractile pharynx; Cnideria: striated muscle cells associated with gastrodermis SPD:0000130 @@ -49544,14 +49721,14 @@ For example, A and B may be gene products and binding of B by A positively regul Gene notes: Bmp, Nkx, Gata primary circulatory organ - + - + GO uses blood circulation generically to include the haemolymphatic fluid of arthropods @@ -49641,7 +49818,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -49658,14 +49835,14 @@ For example, A and B may be gene products and binding of B by A positively regul presumptive segmental plate - + - + https://github.com/obophenotype/uberon/wiki/The-neural-crest EDHAA2 @@ -49764,7 +49941,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -49790,7 +49967,7 @@ For example, A and B may be gene products and binding of B by A positively regul presumptive paraxial mesoderm - + @@ -49806,7 +49983,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + https://github.com/obophenotype/uberon/issues/1277 @@ -49882,7 +50059,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Mesenchyme with little extracellular matrix. AEO:0000146 EHDAA2:0003146 @@ -49890,7 +50067,7 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0007524 dense mesenchyme tissue - + @@ -49903,7 +50080,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + AEO @@ -49993,6 +50170,12 @@ For example, A and B may be gene products and binding of B by A positively regul FBbt:00005426 http://flybase.org/reports/FBrf0178740.html + + + + FBbt:00005426 + + @@ -50000,7 +50183,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Anatomical system that consists of all blood and lymph vessels. consider merging with vasculature @@ -50019,14 +50202,14 @@ For example, A and B may be gene products and binding of B by A positively regul vascular system - + - + MA @@ -50066,7 +50249,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -50083,14 +50266,14 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0009142 entire embryonic mesenchyme - + - + EHDAA2 @@ -50146,7 +50329,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + EHDAA2:0002094 trunk and cervical paraxial mesenchyme uberon @@ -50154,14 +50337,14 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0009618 trunk paraxial mesoderm - + - + EHDAA2 @@ -50183,7 +50366,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + EFO:0003704 TAO:0005041 ZFA:0005041 @@ -50193,14 +50376,14 @@ For example, A and B may be gene products and binding of B by A positively regul anterior lateral plate mesoderm - + - + ZFA @@ -50258,6 +50441,12 @@ For example, A and B may be gene products and binding of B by A positively regul An anatomical structure that has more than one cell as a part. CARO:0010000 + + + + FBbt:00100313 + + @@ -50334,7 +50523,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -50354,14 +50543,14 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0010210 blood clot - + - + BTO @@ -50483,8 +50672,8 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + Anatomical cluster consisting of the skeletal elements (i.e. bone elements, cartilage elements, cartilage condensations) that are part of an individual subdivision of the organism. Excludes joints. Anatomical cluster consisting of the skeletal elements that are part of the skeleton.[VSAO] FMA:23879 @@ -50497,11 +50686,11 @@ For example, A and B may be gene products and binding of B by A positively regul subdivision of skeleton - + - + @@ -50514,13 +50703,13 @@ For example, A and B may be gene products and binding of B by A positively regul - + UBERONREF:0000003 - + VSAO @@ -50591,7 +50780,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Subdivision of the skeletal system which consists of the postcranial axial skeleton plus associated joints. axial skeletal system FMA:302077 @@ -50601,7 +50790,7 @@ For example, A and B may be gene products and binding of B by A positively regul postcranial axial skeletal system http://purl.obolibrary.org/obo/uberon/docs/The-axial-skeleton - + @@ -50614,7 +50803,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + cjm @@ -50647,12 +50836,14 @@ For example, A and B may be gene products and binding of B by A positively regul + FBbt:00007330 FMA:67509 SCTID:91690000 uberon UBERON:0011216 + organ system subdivision @@ -50668,6 +50859,12 @@ For example, A and B may be gene products and binding of B by A positively regul A subdivision of an anatomical system. http://orcid.org/0000-0002-6601-2165 + + + + FBbt:00007330 + + @@ -50879,7 +51076,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -50901,7 +51098,7 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0012429 hematopoietic tissue - + @@ -50914,7 +51111,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + defitional @@ -51077,7 +51274,6 @@ For example, A and B may be gene products and binding of B by A positively regul The region of the organism associated with the visceral organs. - Cardinal body part, which consists of a maximal set of diverse subclasses of organ and organ part spatially associated with the vertebral column and ribcage. Examples: There is only one body proper[FMA:231424]. AEO:0000103 BTO:0001489 @@ -51087,7 +51283,6 @@ For example, A and B may be gene products and binding of B by A positively regul body whole body UBERON:0013702 - body proper @@ -51235,6 +51430,12 @@ For example, A and B may be gene products and binding of B by A positively regul FBC:DOS FBbt:00007278 + + + + FBbt:00007278 + + @@ -51488,7 +51689,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -51511,7 +51712,7 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0016887 entire extraembryonic component - + @@ -51524,7 +51725,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + AEO @@ -51650,6 +51851,12 @@ For example, A and B may be gene products and binding of B by A positively regul Material anatomical entity consisting of multiple anatomical structures that are not connected to each other. CARO:0020000 + + + + FBbt:00007276 + + @@ -52026,6 +52233,24 @@ For example, A and B may be gene products and binding of B by A positively regul + + + + + + + + + + + + + + + + + + @@ -52056,6 +52281,16 @@ For example, A and B may be gene products and binding of B by A positively regul + + + + + + + + + + diff --git a/subsets/blood_and_immune_upper_slim.tsv b/subsets/blood_and_immune_upper_slim.tsv index bc02e85e2..ed97b6166 100644 --- a/subsets/blood_and_immune_upper_slim.tsv +++ b/subsets/blood_and_immune_upper_slim.tsv @@ -1,395 +1,392 @@ ?x ?label -_:B401aa5d3X2D71a9X2D4aa1X2Da48dX2Dfa166a9c6ddagenid1014 -_:B401aa5d3X2D71a9X2D4aa1X2Da48dX2Dfa166a9c6ddagenid1027 -_:B401aa5d3X2D71a9X2D4aa1X2Da48dX2Dfa166a9c6ddagenid1041 -_:B401aa5d3X2D71a9X2D4aa1X2Da48dX2Dfa166a9c6ddagenid1057 -_:B401aa5d3X2D71a9X2D4aa1X2Da48dX2Dfa166a9c6ddagenid1075 -_:B401aa5d3X2D71a9X2D4aa1X2Da48dX2Dfa166a9c6ddagenid1082 -_:B401aa5d3X2D71a9X2D4aa1X2Da48dX2Dfa166a9c6ddagenid1088 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+_:Bfc26b7c9X2D6e5eX2D4e75X2D81bcX2D5596fb9a64a9genid776 +_:Bfc26b7c9X2D6e5eX2D4e75X2D81bcX2D5596fb9a64a9genid829 +_:Bfc26b7c9X2D6e5eX2D4e75X2D81bcX2D5596fb9a64a9genid846 +_:Bfc26b7c9X2D6e5eX2D4e75X2D81bcX2D5596fb9a64a9genid866 +_:Bfc26b7c9X2D6e5eX2D4e75X2D81bcX2D5596fb9a64a9genid881 +_:Bfc26b7c9X2D6e5eX2D4e75X2D81bcX2D5596fb9a64a9genid936 +_:Bfc26b7c9X2D6e5eX2D4e75X2D81bcX2D5596fb9a64a9genid967 "continuant" "occurrent" "independent continuant" @@ -547,7 +544,6 @@ _:B401aa5d3X2D71a9X2D4aa1X2Da48dX2Dfa166a9c6ddagenid970 "acidophilic cytoplasm" "basophilic cytoplasm" "polychromatophilic cytoplasm" - "increased nucleus size" "cartwheel heterochromatin" "bone marrow hematopoietic cell" "peripheral blood mononuclear cell" @@ -966,6 +962,7 @@ _:B401aa5d3X2D71a9X2D4aa1X2Da48dX2Dfa166a9c6ddagenid970 "exocytic process" "extracellular vesicle biogenesis" "export from cell" + "defense response to symbiont" "organic substance biosynthetic process" "regulation of leukocyte differentiation" "mitotic cell cycle process" @@ -1011,15 +1008,10 @@ _:B401aa5d3X2D71a9X2D4aa1X2Da48dX2Dfa166a9c6ddagenid970 "quality" "morphology" "shape" - "qualitative" - "deviation (from_normal)" - "size" "structure" "maturity" "branched" "circular" - "normal" - "increased size" "elliptic" "physical quality" "physical object quality" @@ -1056,13 +1048,12 @@ _:B401aa5d3X2D71a9X2D4aa1X2Da48dX2Dfa166a9c6ddagenid970 "quality of a substance" "3-D shape" "tubular" - "increased quality" - "increased object quality" "superelliptic" "acidophilic" "nucleated" "disconnected" "polymeric" + "high nuclear/cytoplasmic ratio" "anatomical structure quality" "anatomical histological quality" "neutrophillic" diff --git a/subsets/eye_upper_slim.json b/subsets/eye_upper_slim.json index 45ef90be0..8b2e399be 100644 --- a/subsets/eye_upper_slim.json +++ b/subsets/eye_upper_slim.json @@ -4,9 +4,9 @@ "meta" : { "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2002/07/owl#versionInfo", - "val" : "2024-01-04" + "val" : "2024-02-13" } ], - "version" : "http://purl.obolibrary.org/obo/cl/releases/2024-01-04/subsets/eye_upper_slim.owl" + "version" : "http://purl.obolibrary.org/obo/cl/releases/2024-02-13/subsets/eye_upper_slim.owl" }, "nodes" : [ { "id" : "http://purl.obolibrary.org/obo/BFO_0000002", @@ -731,7 +731,7 @@ "xrefs" : [ "CARO:mah" ] }, "comments" : [ "The definition of cell is intended to represent all cells, and thus a cell is defined as a material entity and not an anatomical structure, which implies that it is part of an organism (or the entirety of one)." ], - "subsets" : [ "http://purl.obolibrary.org/obo/ubprop#_upper_level" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/ubprop#_upper_level" ], "xrefs" : [ { "val" : "CALOHA:TS-2035" }, { @@ -767,6 +767,7 @@ "lbl" : "neuronal receptor cell", "type" : "CLASS", "meta" : { + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "neuronal receptor cell (sensu Animalia)" @@ -795,7 +796,10 @@ }, { "id" : "http://purl.obolibrary.org/obo/CL_0000030", "lbl" : "glioblast", - "type" : "CLASS" + "type" : "CLASS", + "meta" : { + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] + } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000031", "lbl" : "neuroblast (sensu Vertebrata)", @@ -805,6 +809,7 @@ "val" : "A cell that will develop into a neuron often after a migration phase.", "xrefs" : [ "GOC:NV", "http://en.wikipedia.org/wiki/Neuroblast" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "neuroblast" @@ -825,7 +830,7 @@ "xrefs" : [ "GOC:tfm", "MESH:D013234" ] }, "comments" : [ "This term applies to metazoan. For plant stem cells, consider using PO:0004011 ‘initial cell’ or its parent PO:0004010 ‘meristematic cell’." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "animal stem cell" @@ -850,7 +855,7 @@ "xrefs" : [ "GOC:add", "GOC:dsd", "GOC:tfm", "PMID:19022770", "http://en.wikipedia.org/wiki/Hematopoietic_stem_cell" ] }, "comments" : [ "Markers differ between species, and two sets of markers have been described for mice. HSCs are reportedly CD34-positive, CD45-positive, CD48-negative, CD150-positive, CD133-positive, and CD244-negative." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "blood forming stem cell" @@ -890,7 +895,7 @@ "val" : "A progenitor cell committed to the erythroid lineage.", "xrefs" : [ "GOC:add", "ISBN:0721601464" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003000", "pred" : "hasRelatedSynonym", @@ -952,7 +957,7 @@ "xrefs" : [ "GOC:add", "ISBN:0878932437", "MESH:D023461" ] }, "comments" : [ "This cell type is intended to be compatible with any vertebrate common myeloid progenitor. For mammalian CMP known to be CD34-positive, please use the term 'common myeloid progenitor, CD34-positive' (CL_0001059)." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "common myeloid precursor" @@ -1006,7 +1011,7 @@ "xrefs" : [ "GOC:add", "GOC:dsd", "GOC:tfm", "MESH:D055015", "PMID:16647566", "http://en.wikipedia.org/wiki/Megakaryocyte-erythroid_progenitor_cell" ] }, "comments" : [ "MEPs are reportedly CD19-negative, CD34-negative, CD45RA-negative, CD110-positive, CD117-positive, and SCA1-negative and reportedly express the transcription factors GATA-1 and NF-E2." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "CFU-EM" @@ -1063,6 +1068,7 @@ "xrefs" : [ "SANBI:mhl" ] }, "comments" : [ "define using PATO mulit-potent or oligopotent?" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "blast cell" @@ -1104,7 +1110,7 @@ "xrefs" : [ "ISBN:0517223651", "MESH:D005347", "http://en.wikipedia.org/wiki/Fibroblast" ] }, "comments" : [ "These cells may be vimentin-positive, fibronectin-positive, fsp1-positive, MMP-1-positive, collagen I-positive, collagen III-positive, and alpha-SMA-negative." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { "val" : "BTO:0000452" }, { @@ -1130,7 +1136,7 @@ "val" : "A cell that is usually found in a two-dimensional sheet with a free surface. The cell has a cytoskeleton that allows for tight cell to cell contact and for cell polarity where apical part is directed towards the lumen and the basal part to the basal lamina.", "xrefs" : [ "FB:ma", "GOC:tfm", "MESH:D004847" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "epitheliocyte" @@ -1165,7 +1171,7 @@ "val" : "An endothelial cell that lines the vasculature.", "xrefs" : [ "GOC:tfm" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cuboidal endothelial cell of vascular tree" @@ -1184,7 +1190,7 @@ "val" : "A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube.", "xrefs" : [ "GO:0002065", "https://orcid.org/0000-0001-5208-3432" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" @@ -1195,6 +1201,7 @@ "lbl" : "squamous epithelial cell", "type" : "CLASS", "meta" : { + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "CALOHA:TS-1249" } ] @@ -1208,7 +1215,7 @@ "val" : "A flattened epithelial cell of mesenchymal origin that lines the serous cavity.", "xrefs" : [ "GOC:tfm", "ISBN:0721662544" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "mesotheliocyte" @@ -1230,7 +1237,7 @@ "val" : "A cell found predominately in the blood.", "xrefs" : [ "GOC:add", "GOC:tfm" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim" ], "xrefs" : [ { "val" : "FMA:62844" }, { @@ -1240,7 +1247,10 @@ }, { "id" : "http://purl.obolibrary.org/obo/CL_0000095", "lbl" : "neuron associated cell", - "type" : "CLASS" + "type" : "CLASS", + "meta" : { + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] + } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000099", "lbl" : "interneuron", @@ -1250,7 +1260,7 @@ "val" : "Most generally any neuron which is not motor or sensory. Interneurons may also refer to neurons whose axons remain within a particular brain region as contrasted with projection neurons which have axons projecting to other brain regions.", "xrefs" : [ "GOC:tfm", "MESH:D007395" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { "val" : "BTO:0003811" }, { @@ -1295,7 +1305,7 @@ "val" : "A type of interneuron that has two neurites, usually an axon and a dendrite, extending from opposite poles of an ovoid cell body.", "xrefs" : [ "GOC:tfm", "ISBN:0444009442" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#BDS_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#BDS_subset", "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "FMA:67282" } ] @@ -1310,7 +1320,7 @@ "xrefs" : [ "GOC:tfm", "MESH:D042783", "PMID:21275341", "http://en.wikipedia.org/wiki/Endothelial_cell", "https://sourceforge.net/tracker/?func=detail&atid=440764&aid=3364936&group_id=36855" ] }, "comments" : [ "From FMA: 9.07.2001: Endothelial cell has always been classified as a kind of epithelial cell, specifically a squamous cell but that is not true. First, endothelial cell can either be squamous or cuboidal (e.g. high-endothelial cell) and secondly, it has different embryological derivation (mesodermal) than a true epithelial cell (ectodermal and endodermal). The basis for present classification is the fact that it comprises the outermost layer or lining of anatomical structures (location-based) but a better structural basis for the differentia is the cytoskeleton of the cell. Endothelial cell has vimentin filaments while an epithelial cell has keratin filaments. [Onard]." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "endotheliocyte" @@ -1334,7 +1344,10 @@ }, { "id" : "http://purl.obolibrary.org/obo/CL_0000123", "lbl" : "neuron associated cell (sensu Vertebrata)", - "type" : "CLASS" + "type" : "CLASS", + "meta" : { + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] + } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000125", "lbl" : "glial cell", @@ -1345,7 +1358,7 @@ "xrefs" : [ "MESH:D009457" ] }, "comments" : [ "Not all glial cells develop from glioblasts, with microglia developing from the mesoderm instead. See https://github.com/obophenotype/cell-ontology/issues/1571" ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "neuroglial cell" @@ -1372,6 +1385,7 @@ "val" : "A neuroglial cell of ectodermal origin, i.e., the astrocytes and oligodendrocytes considered together.", "xrefs" : [ "GOC:tfm", "ISBN:0721662544" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "macrogliocyte" @@ -1399,7 +1413,7 @@ "xrefs" : [ "GOC:dsd", "GOC:tfm", "MESH:D001253", "PMID:11746784", "PMID:12162730", "PMID:12898703", "PMID:20942978", "http://en.wikipedia.org/wiki/Astrocyte" ] }, "comments" : [ "Astrocytes are reportedly CD68-negative, CD121a-positive, CD184-positive, CD192-positive, CRF-positive, EGFR-positive, GFAP-positive, GLUT1-positive, MBP-negative, and NGFR-positive." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "astrocytic glia" @@ -1425,7 +1439,7 @@ "val" : "An hexagonal, flattened, mitochondria-rich endothelial cell that forms a monolayer on the posterior surface of the cornea (the corneal endothelium). Corneal endothelial cells are derived from the neural crest and are responsible for keeping the cornea transparent by maintaining the tissue in a semi-dry state through the action of their ionic pumps and tight junction barrier.", "xrefs" : [ "GOC:tfm", "PMID:21976958", "PMID:23284695", "PMID:34741068", "PMID:36769303" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { "val" : "CALOHA:TS-0172" }, { @@ -1460,6 +1474,7 @@ "xrefs" : [ "FB:ma", "GOC:dsd", "PMCID:PMC2613570", "PMID:10102814", "PMID:16923606", "PMID:17986482", "PMID:19960544", "http://en.wikipedia.org/wiki/Mesenchymal_stem_cell", "http://www.copewithcytokines.de/cope.cgi?key=mesenchymal%20stem%20cells" ] }, "comments" : [ "Many but not all mesenchymal cells derive from the mesoderm. MSCs are reportedly CD3-negative, CD4-negative, CD5-negative, CD8-negative, CD11a-negative, CD11b-negative, CD14-negative, CD19-negative, CD29-positive, CD31-negative, CD34-negative, CD38-negative, CD40-negative, CD44-positive, CD45-negative, CD49-positive, CD54-positive, CD66b-negative, CD79a-negative, CD80-negative, CD102-positive, CD106-positive, CD117-positive, CD121a-positive, CD121b-positive, CD123-positive, CD124-positive, CD133-negative, CD146-positive, CD166-positive, CD271-positive, B220-negative, Gr1-negative, MHCI-positive, MHCII-negative, SSEA4-negative, sca1-positive, Ter119-negative, and glycophorin A-negative. Cultured MSCs are capable of producing stem cell factor, IL7, IL8, IL11, TGF-beta, cofilin, galectin-1, laminin-receptor 1, cyclophilin A, and MMP-2." ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "bone marrow stromal cells" @@ -1548,7 +1563,7 @@ "val" : "A pigment cell derived from the neural crest. Contains melanin-filled pigment granules, which gives a brown to black appearance.", "xrefs" : [ "SANBI:mhl" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "melanophore" @@ -1588,6 +1603,7 @@ "val" : "A cell that specializes in controlled release of one or more substances.", "xrefs" : [ "GOC:tfm", "ISBN:0721662544" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "BTO:0003659" }, { @@ -1602,7 +1618,8 @@ "definition" : { "val" : "A cell whose primary function is to shorten.", "xrefs" : [ "FB:ma" ] - } + }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000187", @@ -1613,6 +1630,7 @@ "val" : "A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns.", "xrefs" : [ "MESH:D032342" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "muscle fiber" @@ -1647,7 +1665,7 @@ "val" : "A non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels. They develop from specialized myoblasts (smooth muscle myoblast).", "xrefs" : [ "MESH:D032389", "PMID:9315361", "http://en.wikipedia.org/wiki/Smooth_muscle_cell" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "non-striated muscle cell" @@ -1700,6 +1718,7 @@ "val" : "A cell specialized to detect and transduce light.", "xrefs" : [ "MESH:D010786" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "BTO:0001060" }, { @@ -1782,6 +1801,7 @@ "val" : "A cell of the middle germ layer of the embryo.", "xrefs" : [ "MESH:D008648" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "mesoblast" @@ -1819,7 +1839,7 @@ "val" : "A red blood cell. In mammals, mature erythrocytes are biconcave disks containing hemoglobin whose function is to transport oxygen.", "xrefs" : [ "GOC:tfm", "MESH:D004912" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "RBC" @@ -1844,6 +1864,7 @@ "lbl" : "eukaryotic cell", "type" : "CLASS", "meta" : { + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "MESH:D005057" } ] @@ -1853,7 +1874,7 @@ "lbl" : "eye photoreceptor cell", "type" : "CLASS", "meta" : { - "subsets" : [ "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" @@ -2043,6 +2064,7 @@ "val" : "A precursor cell destined to differentiate into smooth muscle myocytes.", "xrefs" : [ "GOC:tfm", "MESH:D032390" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "myoblast, smooth muscle", @@ -2080,7 +2102,10 @@ }, { "id" : "http://purl.obolibrary.org/obo/CL_0000529", "lbl" : "pigmented epithelial cell", - "type" : "CLASS" + "type" : "CLASS", + "meta" : { + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] + } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000540", "lbl" : "neuron", @@ -2091,7 +2116,7 @@ "xrefs" : [ "MESH:D009474", "http://en.wikipedia.org/wiki/Neuron" ] }, "comments" : [ "These cells are also reportedly CD4-negative and CD200-positive. They are also capable of producing CD40L and IFN-gamma." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "nerve cell" @@ -2142,7 +2167,7 @@ "val" : "An immature, nucleated erythrocyte occupying the stage of erythropoeisis that follows formation of erythroid progenitor cells. This cell is CD71-positive, has both a nucleus and a nucleolus, and lacks hematopoeitic lineage markers.", "xrefs" : [ "ISBN:0721601464", "PMID:1638021" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "rubriblast", @@ -2266,7 +2291,7 @@ "xrefs" : [ "GOC:dsd", "GOC:tfm", "ISBN:0721601464" ] }, "comments" : [ "Lineage negative is described here as CD2-negative, CD3-negative, CD4-negative, CD5-negative, CD8a-negative, CD14-negative, CD19-negative, CD20-negative, CD56-negative, Ly6g-negative, and Ter119-negative." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "CFU-Meg", @@ -2326,7 +2351,7 @@ "xrefs" : [ "ISBN:0721601464", "MESH:D008533", "PMID:31043076", "http://en.wikipedia.org/wiki/Megakaryocyte" ] }, "comments" : [ "Megakaryocytes are reportedly CD181-positive and CD182-positive." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "megacaryocyte" @@ -2358,7 +2383,7 @@ "val" : "An immature erythrocyte that changes the protein composition of its plasma membrane by exosome formation and extrusion. The types of protein removed differ between species though removal of the transferrin receptor is apparent in mammals and birds.", "xrefs" : [ "GOC:add", "GOC:tfm", "PMID:15946868", "PMID:2037622" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "BTO:0001173" }, { @@ -2376,7 +2401,7 @@ "val" : "Interneuron of the vertebrate retina. They integrate, modulate, and interpose a temporal domain in the visual message presented to the retinal ganglion cells, with which they synapse in the inner plexiform layer. They lack large axons.", "xrefs" : [ "GOC:tfm", "MESH:D025042", "WikipediaVersioned:Amacrine_cell&oldid=1023572246" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "amacrine neuron" @@ -2428,7 +2453,7 @@ "val" : "One of the two photoreceptor cell types in the vertebrate retina. In cones the photopigment is in invaginations of the cell membrane of the outer segment. Cones are less sensitive to light than rods, but they provide vision with higher spatial and temporal acuity, and the combination of signals from cones with different pigments allows color vision.", "xrefs" : [ "MESH:D017949" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "cone", @@ -2455,7 +2480,7 @@ "val" : "An epithelial cell of the cornea.", "xrefs" : [ "GOC:tfm" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "epithelial cell of cornea", @@ -2482,7 +2507,7 @@ "val" : "One of the two photoreceptor cell types of the vertebrate retina. In rods the photopigment is in stacks of membranous disks separate from the outer cell membrane. Rods are more sensitive to light than cones, but rod mediated vision has less spatial and temporal resolution than cone vision.", "xrefs" : [ "MESH:D017948" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "rod", @@ -2509,7 +2534,7 @@ "val" : "Astrocyte-like radial glial cell that extends vertically throughout the retina, with the nucleus are usually in the middle of the inner nuclear layer.", "xrefs" : [ "GOC:NV", "PMID:21911394" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#MISSPELLING", "pred" : "hasExactSynonym", @@ -2538,7 +2563,7 @@ "definition" : { "val" : "A neuron that is capable of some neurotansmission by glutamate secretion." }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { "val" : "FBbt:00100291" }, { @@ -2557,7 +2582,8 @@ "definition" : { "val" : "A non-terminally differentiated cell that is capable of developing into a muscle cell.", "xrefs" : [ "GOC:add" ] - } + }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000681", @@ -2569,6 +2595,7 @@ "xrefs" : [ "GOC:dph" ] }, "comments" : [ "Unlike that of mammals, the brain of adult teleost fish exhibits an intense and widespread neurogenic activity as a result of the persistence of\nradial glial cells acting as neural progenitors throughout life." ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "forebrain radial glial cell" @@ -2618,7 +2645,7 @@ "val" : "The set of neurons that receives neural inputs via bipolar, horizontal and amacrine cells. The axons of these cells make up the optic nerve.", "xrefs" : [ "GOC:dph" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "gangliocyte" @@ -2657,7 +2684,7 @@ "val" : "A neuron that laterally connects other neurons in the inner nuclear layer of the retina.", "xrefs" : [ "ISBN:0195088433" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "horizontal cell" @@ -2689,7 +2716,7 @@ "val" : "A bipolar neuron found in the retina and having connections with photoreceptors cells and neurons in the inner plexiform layer.", "xrefs" : [ "PMID:14689473" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003000", "pred" : "hasRelatedSynonym", @@ -2720,6 +2747,7 @@ "val" : "A cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage.", "xrefs" : [ "GOC:add" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "BTO:0001441" }, { @@ -2738,7 +2766,7 @@ "xrefs" : [ "GOC:add", "GOC:tfm" ] }, "comments" : [ "Note that in FMA erythropoietic cells are types of nucleated erythrocytes and thus don't include erythrocytes." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "erythropoietic cell" @@ -2764,7 +2792,7 @@ "val" : "A nucleated precursor of an erythrocyte that lacks hematopoietic lineage markers.", "xrefs" : [ "GOC:add", "ISBN:0721601464", "PMID:18174176" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "normoblast" @@ -2789,7 +2817,7 @@ "xrefs" : [ "GOC:add", "GOC:tfm", "PMID:19022770" ] }, "comments" : [ "Markers differ between mouse and human." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "MPP" @@ -2817,7 +2845,7 @@ "xrefs" : [ "GOC:add", "GOC:tfm", "PMID:19022770" ] }, "comments" : [ "Note that this is a class of cell types, not an identified single cell type." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "myeloid progenitor cell" @@ -2843,6 +2871,7 @@ "val" : "A cell of a hematopoietic lineage.", "xrefs" : [ "GOC:add", "GO_REF:0000031" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "haematopoietic cell" @@ -2954,6 +2983,7 @@ "xrefs" : [ "GOC:dsd", "GOC:tfm", "PMID:12768659" ] }, "comments" : [ "These cells are reportedly CD31-positive, CD34-positive, CD144-positive, TAL1-positive." ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "vascular endothelial cell" @@ -3047,7 +3077,7 @@ "xrefs" : [ "PMID:15106942" ] }, "comments" : [ "In a consensus model of unidirectional secretion, aqueous humour is formed by transferring solute, principally NaCl, from stroma to posterior chamber, with water passively following the osmotic gradient. Unidirectional secretion comprises three sequential steps. First, NaCl is transferred from the stromal interstitium into the pigmented ciliary epithelial (PE) cells. Second, solute passes from the PE into the non-pigmented ciliary epithelial (NPE) cells through gap junctions. Finally, NPE cells release Na+ and Cl− into the aqueous humour." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "PE cell", @@ -3077,7 +3107,7 @@ "xrefs" : [ "GOC:tfm", "PMID:15106942" ] }, "comments" : [ "In a consensus model of unidirectional secretion, aqueous humour is formed by transferring solute, principally NaCl, from stroma to posterior chamber, with water passively following the osmotic gradient. Unidirectional secretion comprises three sequential steps. First, NaCl is transferred from the stromal interstitium into the pigmented ciliary epithelial (PE) cells. Second, solute passes from the PE into the non-pigmented ciliary epithelial (NPE) cells through gap junctions. Finally, NPE cells release Na+ and Cl− into the aqueous humour." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "NPE cell", @@ -3110,6 +3140,7 @@ "val" : "A cell that is part of the nervous system.", "xrefs" : [ "GOC:tfm", "ISBN:0618947256" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "CALOHA:TS-2040" }, { @@ -3132,6 +3163,7 @@ "val" : "A cell of the supporting or framework tissue of the body, arising chiefly from the embryonic mesoderm and including adipose tissue, cartilage, and bone.", "xrefs" : [ "GOC:tfm", "ISBN:0618947256" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "CALOHA:TS-2096" }, { @@ -3180,7 +3212,7 @@ "val" : "A keratocyte is a specialized fibroblast residing in the cornea stroma that has a flattened, dendritic morphology; located between the lamellae with a large flattened nucleus, and lengthy processes which communicate with neighboring cells. This corneal layer, representing about 85-90% of corneal thickness, is built up from highly regular collagenous lamellae and extracellular matrix components. Keratocytes play the major role in keeping it transparent, healing its wounds, and synthesizing its components. This cell type secretes collagen I, V, VI, and keratan sulfate.", "xrefs" : [ "GOC:tfm", "ISBN:9780702029585" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "corneal fibroblast" @@ -3296,7 +3328,7 @@ "val" : "A blood vessel endothelial cell that is part of the retina.", "xrefs" : [ "GOC:tfm" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" @@ -3317,7 +3349,7 @@ "val" : "An epithelial cell of the retinal pigmented epithelium.", "xrefs" : [ "GOC:tfm" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#eye_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { "val" : "BTO:0004910" }, { @@ -3397,7 +3429,8 @@ "definition" : { "val" : "Any hematopoietic cell that is a precursor of some other hematopoietic cell type.", "xrefs" : [ "GOC:dos" ] - } + }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0008007", @@ -3420,7 +3453,7 @@ "definition" : { "val" : "A non-polarised cell precursor cell that is part of some mesenchyme, is associated with the cell matrix but is not connected to other cells and is capable of migration." }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "mesenchyme cell" @@ -3491,7 +3524,8 @@ "definition" : { "val" : "A cell of the neural crest. Neural crest cells are multipotent. Premigratory neural crest cells are found at the neural plate boarder, some of which will undergo ectomesynchymal transition and delamination to form migratory neural crest cells.", "xrefs" : [ "https://orcid.org/0000-0001-5208-3432", "https://orcid.org/0000-0002-9900-7880" ] - } + }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0011026", @@ -3502,6 +3536,7 @@ "val" : "A precursor cell that has a tendency to differentiate into a specific type of cell. They are descendants of stem cells, only they are more constrained in their differentiation potential or capacity for self-renewal, and are often more limited in both senses.", "xrefs" : [ "ISBN:978-1-62808-994-3", "https://doi.org/10.1016/B978-0-12-409503-8.00002-0" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0001-5208-3432" @@ -3528,7 +3563,8 @@ "val" : "A cell that, by division or terminal differentiation, can give rise to other cell types.", "xrefs" : [ "GOC:dos" ] }, - "comments" : [ "Work is needed on GO 'cell differentiation' before it is clear whether the equivalent class definition 'native cell' that capable_of some 'cell differentiation' works. Also, may want to consider merging this with non-terminally differentiated cell." ] + "comments" : [ "Work is needed on GO 'cell differentiation' before it is clear whether the equivalent class definition 'native cell' that capable_of some 'cell differentiation' works. Also, may want to consider merging this with non-terminally differentiated cell." ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0017502", @@ -3585,23 +3621,6 @@ "val" : "2009-12-28T04:25:23Z" } ] } - }, { - "id" : "http://purl.obolibrary.org/obo/CL_0017505", - "lbl" : "increased nucleus size", - "type" : "CLASS", - "meta" : { - "definition" : { - "val" : "A nucleus size quality which is relatively high compared to the amount of cytoplasm present in the same cell.", - "xrefs" : [ "GOC:tfm" ] - }, - "basicPropertyValues" : [ { - "pred" : "http://purl.org/dc/terms/contributor", - "val" : "https://orcid.org/0000-0003-1980-3228" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", - "val" : "2009-12-23T10:53:24Z" - } ] - } }, { "id" : "http://purl.obolibrary.org/obo/CL_1000432", "lbl" : "conjunctival epithelial cell", @@ -3611,7 +3630,7 @@ "val" : "An epithelial cell that is part of the conjunctiva.", "xrefs" : [ "GOC:tfm" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#eye_upper_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#eye_upper_slim" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "epithelial cell of conjunctiva", @@ -3630,7 +3649,7 @@ "val" : "A smooth muscle cell that is part of the ciliary body.", "xrefs" : [ "GOC:tfm" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#eye_upper_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#eye_upper_slim" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "smooth muscle cell of ciliary body", @@ -4221,7 +4240,7 @@ "type" : "CLASS", "meta" : { "definition" : { - "val" : "A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex).", + "val" : "A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex).", "xrefs" : [ "GOC:pdt" ] }, "comments" : [ "Note that, in addition to forming the root of the cellular component ontology, this term is recommended for the annotation of gene products whose cellular component is unknown. When this term is used for annotation, it indicates that no information was available about the cellular component of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this." ], @@ -4261,7 +4280,7 @@ "xrefs" : [ "GOC:go_curators" ] }, "comments" : [ "Note that this term is intended to annotate gene products that are not attached to the cell surface. For gene products from multicellular organisms which are secreted from a cell but retained within the organism (i.e. released into the interstitial fluid or blood), consider the cellular component term 'extracellular space ; GO:0005615'." ], - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_yeast", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "extracellular" @@ -4379,7 +4398,7 @@ "xrefs" : [ "ISBN:0198547684" ] }, "comments" : [ "Note that for multicellular organisms, the extracellular space refers to everything outside a cell, but still within the organism (excluding the extracellular matrix). Gene products from a multi-cellular organism that are secreted from a cell into the interstitial fluid or blood can therefore be annotated to this term." ], - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "intercellular space" @@ -4469,7 +4488,7 @@ "xrefs" : [ "ISBN:0198547684" ] }, "comments" : [ "Chromosomes include parts that are not part of the chromatin. Examples include the kinetochore." ], - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_yeast", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "interphase chromosome" @@ -4517,7 +4536,7 @@ "val" : "The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.", "xrefs" : [ "ISBN:0198547684" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_yeast", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "xrefs" : [ { "val" : "Wikipedia:Cytoplasm" } ], @@ -4538,7 +4557,7 @@ "val" : "An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins.", "xrefs" : [ "ISBN:0198506732" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_yeast", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "free ribosome", @@ -4573,7 +4592,7 @@ "val" : "The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.", "xrefs" : [ "ISBN:0716731363" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_yeast", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "juxtamembrane" @@ -4663,7 +4682,7 @@ "val" : "The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.", "xrefs" : [ "GOC:go_curators" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "protein anabolism" @@ -4802,7 +4821,7 @@ "xrefs" : [ "GOC:dos", "GOC:dph", "GOC:jl", "GOC:mah" ] }, "comments" : [ "Note that this term should not be used for direct annotation. It should be possible to make a more specific annotation to one of the children of this term, for e.g. to transmembrane transport, to microtubule-based transport or to vesicle-mediated transport." ], - "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "single-organism transport" @@ -5600,7 +5619,7 @@ "val" : "Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538).", "xrefs" : [ "GOC:mah", "GOC:mtg_apoptosis", "PMID:25236395" ] }, - "comments" : [ "This term should not be used for direct annotation, it is currently kept in GO as a placeholder for describing cell death phenotypes in uPHENO. When information is provided on a programmed cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'). Unintentional cell death, i.e. cell death caused by injury, ageing, or cell phenotypes observed as a result of a pathological mutation in an essential gene should NOT be annotated using GO terms." ], + "comments" : [ "This term should not be used for direct annotation, it is currently kept in GO as a placeholder for describing cell death phenotypes in uPHENO. When information is provided on a programmed cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'). Unintentional cell death, i.e. cell death caused by injury, ageing, or cell phenotypes observed as a result of a pathological mutation in an essential gene should NOT be annotated using GO terms." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", @@ -6070,7 +6089,7 @@ "xrefs" : [ "GOC:lr", "GOC:mtg_apoptosis" ] }, "comments" : [ "Note that this term should be used to annotate gene products in the organism undergoing the programmed cell death. To annotate genes in another organism whose products modulate programmed cell death in a host organism, consider the term 'modulation by symbiont of host programmed cell death ; GO:0052040'. Also, note that 'programmed cell death ; GO:0012501' should be used to refer to instances of caspase-independent cell death mechanisms, in the absence of further indications on the process taking place. At present, caspase-independent cell death is not yet represented in GO due to the lack of consensus and in-depth research on the topic. 'programmed cell death ; GO:0012501' may also be used to annotate gene products in taxa where apoptosis as defined in GO:0006915 does not occur, such as plants. You may also consider these specific children: GO:0097468 'programmed cell death in response to reactive oxygen species' (with descendants GO:0010421 'hydrogen peroxide-mediated programmed cell death' and GO:0010343 'singlet oxygen-mediated programmed cell death'), and GO:0009626 'plant-type hypersensitive response' and its children." ], - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "regulated cell death" @@ -6560,7 +6579,7 @@ "xrefs" : [ "GOC:mtg_signal", "GOC:mtg_signaling_feb11", "GOC:signaling" ] }, "comments" : [ "Note that a signal is any variable property or parameter that serves to convey information, and may be a physical entity such as a gene product or small molecule, a photon, or a change in state such as movement or voltage change." ], - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pombe", "http://purl.obolibrary.org/obo/go#goslim_yeast", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pombe", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "biological signaling" @@ -6626,7 +6645,7 @@ "val" : "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon.", "xrefs" : [ "GOC:jl", "GOC:mah", "http://www.cogsci.princeton.edu/~wn/" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cell projection organisation" @@ -6941,7 +6960,7 @@ "val" : "A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues.", "xrefs" : [ "GOC:BHF", "GOC:mah", "GOC:rph", "NIF_Subcellular:nlx_subcell_20090513", "PMID:21123617", "PMID:28089324" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "proteinaceous extracellular matrix" @@ -7566,7 +7585,7 @@ "val" : "A prolongation or process extending from a cell, e.g. a flagellum or axon.", "xrefs" : [ "GOC:jl", "http://www.cogsci.princeton.edu/~wn/" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "cell process" @@ -7672,7 +7691,7 @@ "val" : "The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.", "xrefs" : [ "GOC:mah" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_pir" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_pir" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "biopolymer metabolic process", @@ -7688,6 +7707,9 @@ "val" : "multicellular organismal macromolecule metabolic process" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/26424" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0034960" }, { @@ -7743,7 +7765,7 @@ "val" : "Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane.", "xrefs" : [ "GOC:go_curators" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "xrefs" : [ { "val" : "NIF_Subcellular:sao1539965131" }, { @@ -8071,12 +8093,15 @@ "val" : "The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.", "xrefs" : [ "GOC:go_curators", "http://www.metacyc.org" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_pir" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_pir" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "primary metabolism" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/26424" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] @@ -8401,12 +8426,15 @@ "val" : "The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.", "xrefs" : [ "GO_REF:0000021" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_plant" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_plant" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "development of an anatomical structure" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/26424" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] @@ -8434,7 +8462,7 @@ "val" : "Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another.", "xrefs" : [ "GOC:dgh", "GOC:dph", "GOC:isa_complete", "GOC:mlg" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cell locomotion" @@ -8574,7 +8602,7 @@ "xrefs" : [ "GOC:ai", "GOC:bf" ] }, "comments" : [ "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ], - "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_manually_annotate", "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_manually_annotate", "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "physiological response to stimulus" @@ -9196,7 +9224,7 @@ "val" : "The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex.", "xrefs" : [ "GOC:jl" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_pombe", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_pombe", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cellular protein complex assembly" @@ -9362,6 +9390,7 @@ "val" : "The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon.", "xrefs" : [ "GOC:mah" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "organic molecular entity metabolic process" @@ -9373,6 +9402,9 @@ "val" : "organic substance metabolism" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/26424" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "mah" }, { @@ -9464,7 +9496,7 @@ "type" : "CLASS", "meta" : { "definition" : { - "val" : "The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures.", + "val" : "The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures.", "xrefs" : [ "GOC:pdt" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon" ], @@ -9974,6 +10006,9 @@ "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/24200" + }, { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/26424" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "kmv" @@ -11658,47 +11693,6 @@ "val" : "quality" } ] } - }, { - "id" : "http://purl.obolibrary.org/obo/PATO_0000068", - "lbl" : "qualitative", - "type" : "CLASS", - "meta" : { - "comments" : [ "TODO: define this or obsolete it and move children somewhere else." ], - "basicPropertyValues" : [ { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", - "val" : "quality" - } ] - } - }, { - "id" : "http://purl.obolibrary.org/obo/PATO_0000069", - "lbl" : "deviation (from_normal)", - "type" : "CLASS", - "meta" : { - "definition" : { - "val" : "A quality inhering in a bearer by virtue of the whether the bearer differs from normal or average.", - "xrefs" : [ "PATOC:GVG" ] - }, - "subsets" : [ "http://purl.obolibrary.org/obo/pato#attribute_slim" ], - "basicPropertyValues" : [ { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", - "val" : "quality" - } ] - } - }, { - "id" : "http://purl.obolibrary.org/obo/PATO_0000117", - "lbl" : "size", - "type" : "CLASS", - "meta" : { - "definition" : { - "val" : "A morphology quality inhering in a bearer by virtue of the bearer's physical magnitude.", - "xrefs" : [ "WordNet:WordNet" ] - }, - "subsets" : [ "http://purl.obolibrary.org/obo/pato#attribute_slim", "http://purl.obolibrary.org/obo/pato#scalar_slim" ], - "basicPropertyValues" : [ { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", - "val" : "quality" - } ] - } }, { "id" : "http://purl.obolibrary.org/obo/PATO_0000136", "lbl" : "closure", @@ -11787,65 +11781,6 @@ "val" : "quality" } ] } - }, { - "id" : "http://purl.obolibrary.org/obo/PATO_0000461", - "lbl" : "normal", - "type" : "CLASS", - "meta" : { - "definition" : { - "val" : "A quality inhering in a bearer by virtue of the bearer's exhibiting no deviation from normal or average.", - "xrefs" : [ "PATOC:GVG" ] - }, - "subsets" : [ "http://purl.obolibrary.org/obo/pato#abnormal_slim", "http://purl.obolibrary.org/obo/pato#mpath_slim", "http://purl.obolibrary.org/obo/pato#value_slim" ], - "synonyms" : [ { - "pred" : "hasRelatedSynonym", - "val" : "average" - } ], - "basicPropertyValues" : [ { - "pred" : "http://purl.obolibrary.org/obo/RO_0002604", - "val" : "http://purl.obolibrary.org/obo/PATO_0000460" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", - "val" : "quality" - } ] - } - }, { - "id" : "http://purl.obolibrary.org/obo/PATO_0000586", - "lbl" : "increased size", - "type" : "CLASS", - "meta" : { - "definition" : { - "val" : "A size quality which is relatively high.", - "xrefs" : [ "PATOC:GVG" ] - }, - "subsets" : [ "http://purl.obolibrary.org/obo/pato#value_slim" ], - "synonyms" : [ { - "pred" : "hasRelatedSynonym", - "val" : "big" - }, { - "pred" : "hasRelatedSynonym", - "val" : "enlarged" - }, { - "pred" : "hasRelatedSynonym", - "val" : "expanded" - }, { - "pred" : "hasRelatedSynonym", - "val" : "great" - }, { - "pred" : "hasRelatedSynonym", - "val" : "large" - } ], - "basicPropertyValues" : [ { - "pred" : "http://purl.obolibrary.org/obo/RO_0002604", - "val" : "http://purl.obolibrary.org/obo/PATO_0000587" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", - "val" : "PATO:0001202" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", - "val" : "quality" - } ] - } }, { "id" : "http://purl.obolibrary.org/obo/PATO_0000608", "lbl" : "closed", @@ -12613,52 +12548,6 @@ "val" : "quality" } ] } - }, { - "id" : "http://purl.obolibrary.org/obo/PATO_0002300", - "lbl" : "increased quality", - "type" : "CLASS", - "meta" : { - "definition" : { - "val" : "A quality that has a value that is increased compared to normal or average.", - "xrefs" : [ "PATOC:GVG" ] - }, - "basicPropertyValues" : [ { - "pred" : "http://purl.obolibrary.org/obo/RO_0002604", - "val" : "http://purl.obolibrary.org/obo/PATO_0002301" - }, { - "pred" : "http://purl.org/dc/terms/contributor", - "val" : "https://orcid.org/0000-0002-2061-091X" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", - "val" : "2011-06-16T06:39:43Z" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", - "val" : "quality" - } ] - } - }, { - "id" : "http://purl.obolibrary.org/obo/PATO_0002305", - "lbl" : "increased object quality", - "type" : "CLASS", - "meta" : { - "definition" : { - "val" : "A quality of an object that has a value that is increased compared to normal or average.", - "xrefs" : [ "PATOC:GVG" ] - }, - "basicPropertyValues" : [ { - "pred" : "http://purl.obolibrary.org/obo/RO_0002604", - "val" : "http://purl.obolibrary.org/obo/PATO_0002303" - }, { - "pred" : "http://purl.org/dc/terms/contributor", - "val" : "https://orcid.org/0000-0002-2061-091X" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", - "val" : "2011-06-16T06:54:01Z" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", - "val" : "quality" - } ] - } }, { "id" : "http://purl.obolibrary.org/obo/PATO_0002309", "lbl" : "fiber shaped", @@ -12809,6 +12698,28 @@ "val" : "quality" } ] } + }, { + "id" : "http://purl.obolibrary.org/obo/PATO_0040072", + "lbl" : "high nuclear/cytoplasmic ratio", + "type" : "CLASS", + "meta" : { + "definition" : { + "val" : "A quality inhering in a cell by virtue of the cell having a high nuclear/cytoplasmic ratio.", + "xrefs" : [ "Wikipedia:NC_ratio&oldid=931936284", "http://lymerick.net/blood-cells.pdf" ] + }, + "comments" : [ "A high nuclear/cytolasmic ratio is 70% or higher." ], + "synonyms" : [ { + "pred" : "hasExactSynonym", + "val" : "high N:C ratio" + } ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", + "val" : "http://orcid.org/0000-0001-5208-3432" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "quality" + } ] + } }, { "id" : "http://purl.obolibrary.org/obo/PATO_0070006", "lbl" : "cortical bipolar morphology", @@ -15654,6 +15565,9 @@ "val" : "inverse of develops from" }, "subsets" : [ "http://purl.obolibrary.org/obo/RO_0002259" ], + "xrefs" : [ { + "val" : "RO:0002203" + } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000114", "val" : "http://purl.obolibrary.org/obo/IAO_0000125" @@ -15666,6 +15580,12 @@ }, { "pred" : "http://purl.obolibrary.org/obo/IAO_0000117", "val" : "https://orcid.org/0000-0003-1980-3228" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "uberon" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#shorthand", + "val" : "develops_into" } ] } }, { @@ -20008,7 +19928,7 @@ "val" : "eye", "xrefs" : [ "FMA:54448" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "regio orbitalis", "xrefs" : [ "FMA:54448", "FMA:TA" ] @@ -20308,7 +20228,7 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "tunica serosa", "xrefs" : [ "FMA:9581" ] @@ -21125,7 +21045,7 @@ "val" : "zygote", "xrefs" : [ "VHOG:0000745" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "zygotum", "xrefs" : [ "Wikipedia:Zygote" ] @@ -21457,7 +21377,7 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#efo_slim", "http://purl.obolibrary.org/obo/uberon/core#major_organ", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "regio oralis", "xrefs" : [ "BTO:0004698", "FMA:49184", "FMA:TA" ] @@ -21465,7 +21385,7 @@ "pred" : "hasNarrowSynonym", "val" : "adult mouth" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "cavital oralis", "xrefs" : [ "Wikipedia:Mouth" ] @@ -22483,8 +22403,6 @@ "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#common_anatomy", "http://purl.obolibrary.org/obo/uberon/core#upper_level" ], "xrefs" : [ { "val" : "FBbt:00007277" - }, { - "val" : "IDOMAL:0002461" }, { "val" : "VHOG:0001737" } ], @@ -23534,11 +23452,11 @@ "pred" : "hasExactSynonym", "val" : "cranial II" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "nervus opticus" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "nervus opticus [II]", "xrefs" : [ "FMA:50863", "FMA:TA" ] @@ -23932,7 +23850,7 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "chiasma opticum", "xrefs" : [ "Wikipedia:Optic_chiasm" ] @@ -23945,12 +23863,12 @@ "val" : "optic chiasm", "xrefs" : [ "Wikipedia:Optic_chiasm" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "chiasma", "xrefs" : [ "NeuroNames:459" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "chiasma nervorum opticorum", "xrefs" : [ "NeuroNames:459" ] @@ -24560,7 +24478,7 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "systema cardiovasculare", "xrefs" : [ "Wikipedia:Circulatory_system" ] @@ -24569,6 +24487,8 @@ "val" : "AAO:0000959" }, { "val" : "CALOHA:TS-2103" + }, { + "val" : "MESH:D002319" }, { "val" : "VHOG:0001248" }, { @@ -24626,7 +24546,7 @@ "pred" : "hasExactSynonym", "val" : "musculature" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "musculi", "xrefs" : [ "FMA:32558", "FMA:TA" ] @@ -24700,7 +24620,7 @@ "val" : "The nervous system is an organ system containing predominantly neuron and glial cells. In bilaterally symmetrical organism, it is arranged in a network of tree-like structures connected to a central body. The main functions of the nervous system are to regulate and control body functions, and to receive sensory input, process this information, and generate behavior [CUMBO].", "xrefs" : [ "BIRNLEX:844", "ISBN:0-14-051288-8", "ISBN:3110148986", "NLM:nervous+system", "WB:rynl", "Wikipedia:Nervous_system", "ZFIN:curator" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#cumbo", "http://purl.obolibrary.org/obo/uberon/core#efo_slim", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], + "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#cumbo", "http://purl.obolibrary.org/obo/uberon/core#efo_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "neurological system", @@ -24710,7 +24630,7 @@ "val" : "nerve net", "xrefs" : [ "Wikipedia:Nerve_net" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "systema nervosum", "xrefs" : [ "Wikipedia:Nervous_system" ] @@ -24773,6 +24693,9 @@ "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_6040" + }, { + "pred" : "http://purl.obolibrary.org/obo/RO_0002175", + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" }, { "pred" : "http://purl.obolibrary.org/obo/UBPROP_0000001", "val" : "A regulatory system of the body that consists of neurons and neuroglial cells. The nervous system is divided into two parts, the central nervous system (CNS) and the peripheral nervous system (PNS). (Source: BioGlossary, www.Biology-Text.com)[TAO]" @@ -24808,13 +24731,13 @@ "val" : "The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the neural tube derivatives: the brain and spinal cord. In invertebrates it includes central ganglia plus nerve cord.", "xrefs" : [ "GO:0021551", "http://www.frontiersinzoology.com/content/7/1/29", "https://sourceforge.net/p/geneontology/ontology-requests/11422/" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#cumbo", "http://purl.obolibrary.org/obo/uberon/core#efo_slim", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], + "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#cumbo", "http://purl.obolibrary.org/obo/uberon/core#efo_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], "synonyms" : [ { "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003000", "pred" : "hasExactSynonym", "val" : "CNS" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "systema nervosum centrale", "xrefs" : [ "FMA:55675", "FMA:TA" ] @@ -24885,6 +24808,9 @@ "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099" + }, { + "pred" : "http://purl.obolibrary.org/obo/RO_0002175", + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" }, { "pred" : "http://purl.obolibrary.org/obo/UBPROP_0000001", "val" : "Part of the nervous system which includes the brain and spinal cord.[AAO]" @@ -24970,7 +24896,7 @@ "val" : "fascicle", "xrefs" : [ "FBbt:00005101" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "fasciculus" }, { @@ -25023,7 +24949,7 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#efo_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "organa sensuum", "xrefs" : [ "FMA:75259", "FMA:TA" ] @@ -25047,7 +24973,7 @@ "val" : "sensory systems", "xrefs" : [ "TAO:0000282" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "organa sensuum", "xrefs" : [ "Wikipedia:Sensory_system" ] @@ -25182,7 +25108,7 @@ "pred" : "hasRelatedSynonym", "val" : "presumptive central nervous system" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "tubus neuralis", "xrefs" : [ "Wikipedia:Neural_tube" ] @@ -25333,7 +25259,7 @@ "pred" : "hasExactSynonym", "val" : "smooth muscle" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "textus muscularis nonstriatus", "xrefs" : [ "FMA:14070", "FMA:TA" ] @@ -25346,7 +25272,7 @@ "pred" : "hasNarrowSynonym", "val" : "visceral muscle tissue" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "textus muscularis levis; textus muscularis nonstriatus", "xrefs" : [ "Wikipedia:Smooth_muscle_tissue" ] @@ -25653,7 +25579,7 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "facia/facies", "xrefs" : [ "Wikipedia:Face" ] @@ -25763,6 +25689,8 @@ "val" : "FMA:45615" }, { "val" : "MA:0000917" + }, { + "val" : "MESH:D041981" }, { "val" : "NCIT:C34082" }, { @@ -25832,7 +25760,7 @@ "val" : "ciliaris", "xrefs" : [ "Wikipedia:Ciliary_muscle" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "musculus ciliaris", "xrefs" : [ "Wikipedia:Ciliary_muscle" ] @@ -26032,7 +25960,7 @@ "val" : "camera anterior bulbi", "xrefs" : [ "BTO:0002084" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "camera anterior bulbi oculi", "xrefs" : [ "Wikipedia:Anterior_chamber_of_eyeball" ] @@ -26113,7 +26041,7 @@ "val" : "tunica vasculatis oculi", "xrefs" : [ "Wikipedia:Uvea" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "tunica vasculosa bulbi", "xrefs" : [ "Wikipedia:Uvea" ] @@ -26269,7 +26197,7 @@ "pred" : "hasExactSynonym", "val" : "epithelium anterius (cornea)" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "epithelium anterius corneae", "xrefs" : [ "FMA:58263", "FMA:TA" ] @@ -26287,7 +26215,7 @@ "val" : "anterior endothelium of cornea", "xrefs" : [ "BTO:0000287" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "e. anterius corneae", "xrefs" : [ "Wikipedia:Corneal_epithelium" ] @@ -26459,7 +26387,7 @@ "val" : "ciliary bodies", "xrefs" : [ "VHOG:0000102" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "corpus ciliare", "xrefs" : [ "Wikipedia:Ciliary_body" ] @@ -26546,7 +26474,7 @@ "val" : "chorioid", "xrefs" : [ "BTO:0001829" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "choroidea", "xrefs" : [ "Wikipedia:Choroid" ] @@ -26627,7 +26555,7 @@ "pred" : "hasExactSynonym", "val" : "stroma of cornea" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "substantia propria corneae", "xrefs" : [ "FMA:58306", "FMA:TA" ] @@ -26809,7 +26737,7 @@ "pred" : "hasExactSynonym", "val" : "stratum pigmentosum (retina)" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "stratum pigmentosum retinae", "xrefs" : [ "FMA:58627", "FMA:TA" ] @@ -26824,7 +26752,7 @@ "val" : "epithelium, retinal pigment", "xrefs" : [ "BTO:0001177" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "p. pigmentosa retinae", "xrefs" : [ "Wikipedia:Retinal_pigment_epithelium" ] @@ -26839,7 +26767,7 @@ "val" : "retinal pigment layer", "xrefs" : [ "VHOG:0000536" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "stratum pigmentosa retinae", "xrefs" : [ "Wikipedia:Retinal_pigment_epithelium" ] @@ -26922,7 +26850,7 @@ "pred" : "hasExactSynonym", "val" : "stratum segmentorum externorum et internorum (retina)" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "stratum segmentorum externorum et internorum retinae", "xrefs" : [ "FMA:58680", "FMA:TA" ] @@ -27008,7 +26936,7 @@ "pred" : "hasExactSynonym", "val" : "stratum limitans externum (retina)" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "stratum limitans externum retinae", "xrefs" : [ "FMA:58683", "FMA:TA" ] @@ -27080,7 +27008,7 @@ "pred" : "hasExactSynonym", "val" : "stratum nucleare externum (retina)" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "stratum nucleare externum retinae", "xrefs" : [ "FMA:58684", "FMA:TA" ] @@ -27171,7 +27099,7 @@ "pred" : "hasExactSynonym", "val" : "stratum plexiforme externum" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "stratum plexiforme externum retinae", "xrefs" : [ "FMA:58685", "FMA:TA" ] @@ -27259,7 +27187,7 @@ "pred" : "hasExactSynonym", "val" : "stratum nucleare internum" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "stratum nucleare internum retinae", "xrefs" : [ "FMA:58686", "FMA:TA" ] @@ -27366,7 +27294,7 @@ "val" : "retina, ganglion cell layer", "xrefs" : [ "BAMS:Rgcl" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "stratum ganglionicum retinae", "xrefs" : [ "Wikipedia:Ganglion_cell_layer" ] @@ -27453,7 +27381,7 @@ "pred" : "hasExactSynonym", "val" : "stratum neurofibrarum (retina)" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "stratum neurofibrarum retinae", "xrefs" : [ "FMA:58688", "FMA:TA" ] @@ -27474,7 +27402,7 @@ "val" : "optic fiber layers", "xrefs" : [ "TAO:0002212" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "stratum neurofibrum retinae", "xrefs" : [ "Wikipedia:Nerve_fiber_layer" ] @@ -27547,7 +27475,7 @@ "pred" : "hasExactSynonym", "val" : "retina internal limiting lamina" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "stratum limitans internum retinae", "xrefs" : [ "FMA:58689", "FMA:TA" ] @@ -27634,7 +27562,7 @@ "val" : "stratum plexifome internum", "xrefs" : [ "BTO:0003175" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "stratum plexiforme internum retinae", "xrefs" : [ "Wikipedia:Inner_plexiform_layer" ] @@ -27708,7 +27636,7 @@ "val" : "aqueous humour", "xrefs" : [ "EHDAA2:0000139" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "humor aquosus", "xrefs" : [ "FMA:58819", "FMA:TA" ] @@ -27777,7 +27705,7 @@ "pred" : "hasExactSynonym", "val" : "humor vitreous" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "humor vitreus", "xrefs" : [ "FMA:58822", "FMA:TA" ] @@ -27819,6 +27747,8 @@ "val" : "FMA:58822" }, { "val" : "MA:0001286" + }, { + "val" : "MESH:D014822" }, { "val" : "NCIT:C13323" }, { @@ -27891,7 +27821,7 @@ "val" : "camera postrema", "xrefs" : [ "FMA:58848" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "camera postrema bulbi oculi", "xrefs" : [ "FMA:58848", "FMA:TA" ] @@ -27966,7 +27896,7 @@ "pred" : "hasExactSynonym", "val" : "segmentum anterius (bulbus oculi)" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "segmentum anterius bulbi oculi", "xrefs" : [ "Wikipedia:Anterior_segment_of_eyeball" ] @@ -28031,7 +27961,7 @@ "pred" : "hasExactSynonym", "val" : "segmentum posterius (bulbus oculi)" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "segmentum posterius bulbi oculi", "xrefs" : [ "Wikipedia:Posterior_segment_of_eyeball" ] @@ -28082,7 +28012,7 @@ "val" : "conjunctivas", "xrefs" : [ "XAO:0000182" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "tunica conjunctiva", "xrefs" : [ "FMA:TA" ] @@ -28250,7 +28180,7 @@ "val" : "MB", "xrefs" : [ "BIRNLEX:1667", "NIFSTD:NeuroNames_abbrevSource" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "mesencephalon", "xrefs" : [ "Wikipedia:Midbrain" ] @@ -28386,7 +28316,7 @@ "val" : "betweenbrain", "xrefs" : [ "BTO:0000342" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "diencephalon", "xrefs" : [ "Wikipedia:Diencephalon" ] @@ -28516,12 +28446,12 @@ "val" : "medulla", "xrefs" : [ "ABA:MY" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "bulbus", "xrefs" : [ "FMA:62004", "FMA:TA" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "medulla oblonzata", "xrefs" : [ "Wikipedia:Medulla_oblongata" ] @@ -28632,12 +28562,12 @@ "val" : "optic tracts", "xrefs" : [ "ZFA:0000252" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "tractus optici", "xrefs" : [ "NeuroNames:460" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "tractus opticus", "xrefs" : [ "Wikipedia:Optic_tract" ] @@ -28732,7 +28662,7 @@ "val" : "tegmentum", "xrefs" : [ "ISBN:0471888893" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "tegmentum mesencephali", "xrefs" : [ "Wikipedia:Midbrain_tegmentum" ] @@ -28744,7 +28674,7 @@ "val" : "mesencephalic tegmentum", "xrefs" : [ "VHOG:0001367" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "tegmentum mesencephalicum", "xrefs" : [ "NeuroNames:491" ] @@ -28771,6 +28701,8 @@ "val" : "MA:0000212" }, { "val" : "MAT:0000452" + }, { + "val" : "MESH:D013681" }, { "val" : "SCTID:362392007" }, { @@ -28882,7 +28814,7 @@ "val" : "vascular tree organ region", "xrefs" : [ "FMA:50722" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "vas sanguineum", "xrefs" : [ "Wikipedia:Blood_vessel" ] @@ -28984,7 +28916,7 @@ "val" : "endothelium of cornea", "xrefs" : [ "OBOL:automatic" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "epithelium posterius corneae", "xrefs" : [ "Wikipedia:Corneal_endothelium" ] @@ -29099,7 +29031,7 @@ "val" : "neuronal grey matter", "xrefs" : [ "AEO:0001012" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "substantia grisea", "xrefs" : [ "FMA:67242", "FMA:TA" ] @@ -29108,7 +29040,7 @@ "val" : "gray mater", "xrefs" : [ "ZFA:0001681" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "grisea" } ], @@ -29492,6 +29424,8 @@ "val" : "MA:0002986" }, { "val" : "MAT:0000148" + }, { + "val" : "MESH:D013131" }, { "val" : "MIAA:0000148" }, { @@ -29882,7 +29816,7 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "cavitas thoracis", "xrefs" : [ "Wikipedia:Thoracic_cavity" ] @@ -29962,17 +29896,17 @@ "val" : "cerebrocerebellar fissure", "xrefs" : [ "NeuroNames:22" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "fissura cerebro-cerebellaris", "xrefs" : [ "NeuroNames:22" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "fissura cerebrocerebellaris", "xrefs" : [ "NeuroNames:22" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "medulla spinalis", "xrefs" : [ "BTO:0001279", "Wikipedia:Spinal_cord" ] @@ -30089,7 +30023,7 @@ "val" : "brain stem", "xrefs" : [ "ABA:BS" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "truncus encephali", "xrefs" : [ "Wikipedia:Brainstem" ] @@ -30098,27 +30032,27 @@ "val" : "accessory medullary lamina of pallidum", "xrefs" : [ "NeuroNames:236" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "lamella pallidi incompleta", "xrefs" : [ "NeuroNames:236" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "lamina medullaris accessoria", "xrefs" : [ "NeuroNames:236" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "lamina medullaris incompleta pallidi", "xrefs" : [ "NeuroNames:236" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "lamina pallidi incompleta", "xrefs" : [ "NeuroNames:236" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "truncus encephalicus", "xrefs" : [ "BTO:0000146" ] @@ -30222,7 +30156,7 @@ "val" : "CNS white matter", "xrefs" : [ "TAO:0002143" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "substantia alba", "xrefs" : [ "Wikipedia:White_matter" ] @@ -30404,7 +30338,7 @@ "val" : "notocord", "xrefs" : [ "ZFA:0000135" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "notochorda", "xrefs" : [ "Wikipedia:Notochord" ] @@ -30517,7 +30451,7 @@ "pred" : "hasRelatedSynonym", "val" : "somitic mesoderm" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "somitus", "xrefs" : [ "Wikipedia:Somite" ] @@ -30613,7 +30547,7 @@ "val" : "NC", "xrefs" : [ "XAO:0000048" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "crista neuralis", "xrefs" : [ "Wikipedia:Neural_crest" ] @@ -30707,7 +30641,7 @@ "pred" : "hasExactSynonym", "val" : "neuroectoderm" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "epithelium tubi neuralis; neuroectoderma", "xrefs" : [ "Wikipedia:Neuroectoderm" ] @@ -31037,7 +30971,7 @@ "val" : "epithelium pigmentosum (iris)", "xrefs" : [ "FMA:58517" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "epithelium pigmentosum iridis", "xrefs" : [ "FMA:58517", "FMA:TA" ] @@ -31095,7 +31029,7 @@ "val" : "ectoblast", "xrefs" : [ "MP:0003886" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "epiblastus", "xrefs" : [ "Wikipedia:Epiblast" ] @@ -31733,7 +31667,7 @@ "val" : "lens placodes", "xrefs" : [ "ZFA:0000122" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "placoda lentis", "xrefs" : [ "Wikipedia:Lens_placode" ] @@ -31793,7 +31727,7 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "lamina neuralis", "xrefs" : [ "Wikipedia:Neural_plate" ] @@ -31895,7 +31829,7 @@ "val" : "somitic mesoderm", "xrefs" : [ "ISBN:9780878932504" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "mesoderma paraxiale", "xrefs" : [ "Wikipedia:Paraxial_mesoderm" ] @@ -31998,7 +31932,7 @@ "val" : "lateral plate mesenchyme", "xrefs" : [ "EHDAA2:0000919" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "mesoderma laminae lateralis", "xrefs" : [ "Wikipedia:Lateral_plate_mesoderm" ] @@ -32119,7 +32053,7 @@ "val" : "sclerotomes", "xrefs" : [ "TAO:0001080" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "sclerotomus", "xrefs" : [ "Wikipedia:Sclerotome" ] @@ -32184,7 +32118,7 @@ "val" : "optic stalks", "xrefs" : [ "ZFA:0000137" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "pedunculus opticus", "xrefs" : [ "Wikipedia:Optic_stalk" ] @@ -32254,7 +32188,7 @@ "pred" : "hasExactSynonym", "val" : "head NCC population" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "crista neuralis cranialis", "xrefs" : [ "Wikipedia:Cranial_neural_crest" ] @@ -32368,7 +32302,7 @@ "pred" : "hasExactSynonym", "val" : "portion of mesenchyme tissue" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "mesenchyma", "xrefs" : [ "Wikipedia:Mesenchyme" ] @@ -32991,7 +32925,7 @@ "val" : "stratum nervosum (retina)", "xrefs" : [ "FMA:58628" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "stratum nervosum retinae", "xrefs" : [ "FMA:58628", "FMA:TA" ] @@ -33803,7 +33737,7 @@ "val" : "lamina limitans posterior", "xrefs" : [ "FMA:58309" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "lamina limitans posterior corneae", "xrefs" : [ "FMA:58309", "FMA:TA" ] @@ -33893,12 +33827,12 @@ "val" : "lamina limitans anterior (cornea)", "xrefs" : [ "FMA:58273" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "lamina limitans anterior corneae", "xrefs" : [ "FMA:58273", "FMA:TA" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#DUBIOUS", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003002", "pred" : "hasRelatedSynonym", "val" : "Reichert's membrane", "xrefs" : [ "http://sourceforge.net/tracker/?func=detail&aid=2956371&group_id=76834&atid=974957" ] @@ -34100,7 +34034,7 @@ "val" : "An endothelium that lines the blood vasculature. Other endothelia may line lymph vessels, the heart.", "xrefs" : [ "https://orcid.org/0000-0002-6601-2165" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], + "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], "xrefs" : [ { "val" : "BTO:0000766" }, { @@ -34119,6 +34053,9 @@ "val" : "ZFA:0005257" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/RO_0002175", + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "uberon" } ] @@ -35505,7 +35442,7 @@ "val" : "basement membrane of connective tissue", "xrefs" : [ "FMA:63872" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "membrana basalis", "xrefs" : [ "Wikipedia:Basement_membrane" ] @@ -35626,7 +35563,7 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "skeleton axiale", "xrefs" : [ "Wikipedia:Axial_skeleton" ] @@ -35684,7 +35621,7 @@ "val" : "nerve fibre", "xrefs" : [ "FMA:5914" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "neurofibra", "xrefs" : [ "FMA:5914", "FMA:TA" ] @@ -35698,7 +35635,7 @@ "val" : "nerve fibers", "xrefs" : [ "BAMS:nfi" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "neurofibra", "xrefs" : [ "Wikipedia:Nerve_fiber" ] @@ -37785,7 +37722,7 @@ "val" : "ciliary processes set", "xrefs" : [ "FMA:76551" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "processus ciliares", "xrefs" : [ "FMA:TA" ] @@ -37798,7 +37735,7 @@ "val" : "ciliary process", "xrefs" : [ "Wikipedia:Ciliary_processes" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "processus ciliares", "xrefs" : [ "Wikipedia:Ciliary_processes" ] @@ -37948,7 +37885,7 @@ "val" : "A subdivision of an anatomical system.", "xrefs" : [ "http://orcid.org/0000-0002-6601-2165" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#common_anatomy", "http://purl.obolibrary.org/obo/uberon/core#upper_level" ], + "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#common_anatomy", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#upper_level" ], "xrefs" : [ { "val" : "FBbt:00007330" }, { @@ -37965,6 +37902,9 @@ }, { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_4751" + }, { + "pred" : "http://purl.obolibrary.org/obo/RO_0002175", + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "uberon" @@ -38142,12 +38082,12 @@ "xrefs" : [ "FMA:19783" ] }, "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "textus connectivus collagenosus laxus", "xrefs" : [ "FMA:19783", "FMA:TA" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "textus connectivus laxus", "xrefs" : [ "FMA:19783", "FMA:TA" ] @@ -38413,7 +38353,7 @@ "val" : "The region of the organism associated with the visceral organs.", "xrefs" : [ "AEO:0000103" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#non_informative" ], + "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#non_informative" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "body", @@ -38433,9 +38373,6 @@ "val" : "FMA:231424" } ], "basicPropertyValues" : [ { - "pred" : "http://purl.obolibrary.org/obo/RO_0002175", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" - }, { "pred" : "http://purl.obolibrary.org/obo/UBPROP_0000001", "val" : "Cardinal body part, which consists of a maximal set of diverse subclasses of organ and organ part spatially associated with the vertebral column and ribcage. Examples: There is only one body proper[FMA:231424]." }, { @@ -39012,7 +38949,7 @@ "xrefs" : [ "HPO:pr", "UBERON:cjm", "http://medical-dictionary.thefreedictionary.com/ocular+adnexa", "https://github.com/obophenotype/uberon/issues/1132" ] }, "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "adnexa oculi", "xrefs" : [ "http://medical-dictionary.thefreedictionary.com/ocular+adnexa" ] @@ -39047,7 +38984,7 @@ "val" : "set of accessory visual structures", "xrefs" : [ "FMA:76554" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "structurae oculi accessoriae", "xrefs" : [ "Wikipedia:Accessory_visual_structures" ] @@ -39195,8 +39132,10 @@ "val" : "OBSOLETE A relation between a cell and molecule or complex such that every instance of the cell has a high number of instances of that molecule expressed on the cell surface. For the formal definition, see Masci et al (PMID:19243617).", "xrefs" : [ "PMID:19243617" ] }, - "comments" : [ "Replaced with RO:0015015, see https://github.com/obophenotype/cell-ontology/issues/1481" ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/obophenotype/cell-ontology/issues/1481" + }, { "pred" : "http://purl.obolibrary.org/obo/IAO_0100001", "val" : "http://purl.obolibrary.org/obo/RO_0015015" } ], @@ -39211,8 +39150,10 @@ "val" : "OBSOLETE A relation between a cell and molecule or complex such that every instance of the cell has a low number of instances of that molecule expressed on the cell surface. For the formal definition, see Masci et al (PMID:19243617).", "xrefs" : [ "PMID:19243617" ] }, - "comments" : [ "Replaced with RO:0015016, see https://github.com/obophenotype/cell-ontology/issues/1481" ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/obophenotype/cell-ontology/issues/1481" + }, { "pred" : "http://purl.obolibrary.org/obo/IAO_0100001", "val" : "http://purl.obolibrary.org/obo/RO_0015016" } ], @@ -39442,13 +39383,12 @@ "lbl" : "transitively anteriorly connected to", "type" : "PROPERTY", "meta" : { - "definition" : { - "val" : ".", - "xrefs" : [ "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" ] - }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "uberon" + }, { + "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", + "val" : "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" } ] } }, { @@ -39456,13 +39396,12 @@ "lbl" : "transitively distally connected to", "type" : "PROPERTY", "meta" : { - "definition" : { - "val" : ".", - "xrefs" : [ "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" ] - }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "uberon" + }, { + "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", + "val" : "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" } ] } }, { @@ -39470,13 +39409,12 @@ "lbl" : "transitively proximally connected to", "type" : "PROPERTY", "meta" : { - "definition" : { - "val" : ".", - "xrefs" : [ "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" ] - }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "uberon" + }, { + "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", + "val" : "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" } ] } }, { @@ -40544,10 +40482,6 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0000547", "pred" : "http://purl.obolibrary.org/obo/BFO_0000051", "obj" : "http://purl.obolibrary.org/obo/CL_0017503" - }, { - "sub" : "http://purl.obolibrary.org/obo/CL_0000547", - "pred" : "http://purl.obolibrary.org/obo/BFO_0000051", - "obj" : "http://purl.obolibrary.org/obo/CL_0017505" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000547", "pred" : "http://purl.obolibrary.org/obo/BFO_0000051", @@ -40596,6 +40530,10 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0000547", "pred" : "http://purl.obolibrary.org/obo/CL_4030046", "obj" : "http://purl.obolibrary.org/obo/PR_000002978" + }, { + "sub" : "http://purl.obolibrary.org/obo/CL_0000547", + "pred" : "http://purl.obolibrary.org/obo/RO_0000053", + "obj" : "http://purl.obolibrary.org/obo/PATO_0040072" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000547", "pred" : "http://purl.obolibrary.org/obo/RO_0002104", @@ -41554,14 +41492,6 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0017504", "pred" : "http://purl.obolibrary.org/obo/RO_0000053", "obj" : "http://purl.obolibrary.org/obo/PATO_0070047" - }, { - "sub" : "http://purl.obolibrary.org/obo/CL_0017505", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/GO_0005634" - }, { - "sub" : "http://purl.obolibrary.org/obo/CL_0017505", - "pred" : "http://purl.obolibrary.org/obo/RO_0000053", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000586" }, { "sub" : "http://purl.obolibrary.org/obo/CL_1000432", "pred" : "is_a", @@ -43872,18 +43802,6 @@ "sub" : "http://purl.obolibrary.org/obo/PATO_0000052", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/PATO_0000051" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0000068", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000001" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0000069", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000068" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0000117", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000051" }, { "sub" : "http://purl.obolibrary.org/obo/PATO_0000136", "pred" : "is_a", @@ -43900,18 +43818,6 @@ "sub" : "http://purl.obolibrary.org/obo/PATO_0000411", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/PATO_0000947" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0000461", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000068" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0000586", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000117" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0000586", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0002305" }, { "sub" : "http://purl.obolibrary.org/obo/PATO_0000608", "pred" : "is_a", @@ -44076,22 +43982,6 @@ "sub" : "http://purl.obolibrary.org/obo/PATO_0002299", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/PATO_0002078" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0002300", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000069" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0002300", - "pred" : "http://purl.obolibrary.org/obo/RO_0015007", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000461" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0002305", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0001241" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0002305", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0002300" }, { "sub" : "http://purl.obolibrary.org/obo/PATO_0002309", "pred" : "is_a", @@ -44120,6 +44010,10 @@ "sub" : "http://purl.obolibrary.org/obo/PATO_0015006", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/PATO_0000141" + }, { + "sub" : "http://purl.obolibrary.org/obo/PATO_0040072", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/PATO_0001396" }, { "sub" : "http://purl.obolibrary.org/obo/PATO_0070006", "pred" : "is_a", @@ -52679,9 +52573,6 @@ "restrictions" : [ { "propertyId" : "http://purl.obolibrary.org/obo/BFO_0000051", "fillerId" : "http://purl.obolibrary.org/obo/CL_0017503" - }, { - "propertyId" : "http://purl.obolibrary.org/obo/BFO_0000051", - "fillerId" : "http://purl.obolibrary.org/obo/CL_0017505" }, { "propertyId" : "http://purl.obolibrary.org/obo/BFO_0000051", "fillerId" : "http://purl.obolibrary.org/obo/GO_0005730" @@ -52721,6 +52612,9 @@ }, { "propertyId" : "http://purl.obolibrary.org/obo/RO_0000053", "fillerId" : "http://purl.obolibrary.org/obo/PATO_0002505" + }, { + "propertyId" : "http://purl.obolibrary.org/obo/RO_0000053", + "fillerId" : "http://purl.obolibrary.org/obo/PATO_0040072" }, { "propertyId" : "http://purl.obolibrary.org/obo/RO_0002104", "fillerId" : "http://purl.obolibrary.org/obo/PR_000001945" @@ -53175,13 +53069,6 @@ "propertyId" : "http://purl.obolibrary.org/obo/RO_0000053", "fillerId" : "http://purl.obolibrary.org/obo/PATO_0070047" } ] - }, { - "definedClassId" : "http://purl.obolibrary.org/obo/CL_0017505", - "genusIds" : [ "http://purl.obolibrary.org/obo/GO_0005634" ], - "restrictions" : [ { - "propertyId" : "http://purl.obolibrary.org/obo/RO_0000053", - "fillerId" : "http://purl.obolibrary.org/obo/PATO_0000586" - } ] }, { "definedClassId" : "http://purl.obolibrary.org/obo/CL_1000432", "genusIds" : [ "http://purl.obolibrary.org/obo/CL_0000066" ], @@ -53950,27 +53837,6 @@ "propertyId" : "http://purl.obolibrary.org/obo/BFO_0000050", "fillerId" : "http://purl.obolibrary.org/obo/GO_0005576" } ] - }, { - "definedClassId" : "http://purl.obolibrary.org/obo/PATO_0000586", - "genusIds" : [ "http://purl.obolibrary.org/obo/PATO_0000117" ], - "restrictions" : [ { - "propertyId" : "http://purl.obolibrary.org/obo/RO_0015007", - "fillerId" : "http://purl.obolibrary.org/obo/PATO_0000461" - } ] - }, { - "definedClassId" : "http://purl.obolibrary.org/obo/PATO_0002300", - "genusIds" : [ "http://purl.obolibrary.org/obo/PATO_0000001" ], - "restrictions" : [ { - "propertyId" : "http://purl.obolibrary.org/obo/RO_0015007", - "fillerId" : "http://purl.obolibrary.org/obo/PATO_0000461" - } ] - }, { - "definedClassId" : "http://purl.obolibrary.org/obo/PATO_0002305", - "genusIds" : [ "http://purl.obolibrary.org/obo/PATO_0001241" ], - "restrictions" : [ { - "propertyId" : "http://purl.obolibrary.org/obo/RO_0015007", - "fillerId" : "http://purl.obolibrary.org/obo/PATO_0000461" - } ] }, { "definedClassId" : "http://purl.obolibrary.org/obo/PR_000029032", "genusIds" : [ "http://purl.obolibrary.org/obo/PR_000000001" ], diff --git a/subsets/eye_upper_slim.obo b/subsets/eye_upper_slim.obo index 700f7144d..998c256f5 100644 --- a/subsets/eye_upper_slim.obo +++ b/subsets/eye_upper_slim.obo @@ -1,5 +1,5 @@ format-version: 1.2 -data-version: cl/releases/2024-01-04/subsets/eye_upper_slim.owl +data-version: cl/releases/2024-02-13/subsets/eye_upper_slim.owl subsetdef: abnormal_slim "" subsetdef: added_for_HCA "" subsetdef: attribute_slim "" @@ -31,6 +31,7 @@ subsetdef: goslim_mouse "" subsetdef: goslim_pir "" subsetdef: goslim_plant "" subsetdef: goslim_pombe "" +subsetdef: goslim_prokaryote "" subsetdef: goslim_synapse "" subsetdef: goslim_yeast "" subsetdef: grouping_class "" @@ -49,7 +50,6 @@ subsetdef: non_informative "" subsetdef: organ_slim "" subsetdef: pheno_slim "" subsetdef: phenotype_rcn "" -subsetdef: prokaryote_subset "" subsetdef: ro-eco "" subsetdef: RO:0002259 "" subsetdef: scalar_slim "" @@ -62,7 +62,6 @@ subsetdef: vertebrate_core "" synonymtypedef: blast_name "" synonymtypedef: COMPARATIVE_PREFERRED "" synonymtypedef: DEPRECATED "" -synonymtypedef: DUBIOUS "" synonymtypedef: equivalent_name "" synonymtypedef: genbank_common_name "" synonymtypedef: Gene-based "" @@ -71,13 +70,14 @@ synonymtypedef: HUMAN_PREFERRED "" synonymtypedef: HUMAN_PREFERRED "preferred term when talking about an instance of this class in Homo sapiens" synonymtypedef: in_part "" synonymtypedef: INCONSISTENT "" -synonymtypedef: LATIN "" synonymtypedef: LATIN "latin term" synonymtypedef: MISSPELLING "a mis-spelling that is in common use and thus recorded" synonymtypedef: NON_MAMMAL "" synonymtypedef: OMO:0003000 "abbreviation" +synonymtypedef: OMO:0003002 "" synonymtypedef: OMO:0003003 "" synonymtypedef: OMO:0003004 "plural form" +synonymtypedef: OMO:0003011 "" synonymtypedef: PENDING_REVIEW "" synonymtypedef: PLURAL "plural term" synonymtypedef: PRO-short-label "" @@ -88,7 +88,7 @@ synonymtypedef: synonym "" synonymtypedef: SYSTEMATIC "" synonymtypedef: systematic_synonym "" ontology: cl/subsets/eye_upper_slim -property_value: owl:versionInfo "2024-01-04" xsd:string +property_value: owl:versionInfo "2024-02-13" xsd:string [Term] id: BFO:0000002 @@ -144,6 +144,7 @@ id: CL:0000000 name: cell def: "A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane." [CARO:mah] comment: The definition of cell is intended to represent all cells, and thus a cell is defined as a material entity and not an anatomical structure, which implies that it is part of an organism (or the entirety of one). +subset: cellxgene_subset subset: ubprop:upper_level xref: CALOHA:TS-2035 xref: FBbt:00007002 @@ -172,6 +173,7 @@ relationship: develops_from CL:0000008 ! migratory cranial neural crest cell [Term] id: CL:0000006 name: neuronal receptor cell +subset: cellxgene_subset synonym: "neuronal receptor cell (sensu Animalia)" EXACT [] is_a: CL:0000101 ! sensory neuron is_a: CL:0000197 ! sensory receptor cell @@ -194,6 +196,7 @@ is_a: CL:0000333 ! migratory neural crest cell [Term] id: CL:0000030 name: glioblast +subset: cellxgene_subset is_a: CL:0000055 ! non-terminally differentiated cell relationship: develops_from CL:0000133 ! neurectodermal cell @@ -201,6 +204,7 @@ relationship: develops_from CL:0000133 ! neurectodermal cell id: CL:0000031 name: neuroblast (sensu Vertebrata) def: "A cell that will develop into a neuron often after a migration phase." [GOC:NV, http://en.wikipedia.org/wiki/Neuroblast] +subset: cellxgene_subset synonym: "neuroblast" EXACT [] xref: BTO:0000930 xref: FMA:70563 @@ -213,6 +217,7 @@ id: CL:0000034 name: stem cell def: "A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells." [GOC:tfm, MESH:D013234] comment: This term applies to metazoan. For plant stem cells, consider using PO:0004011 ‘initial cell’ or its parent PO:0004010 ‘meristematic cell’. +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "animal stem cell" EXACT [] @@ -231,6 +236,7 @@ name: hematopoietic stem cell def: "A stem cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system. Hematopoietic stem cells lack cell markers of effector cells (lin-negative). Lin-negative is defined by lacking one or more of the following cell surface markers: CD2, CD3 epsilon, CD4, CD5 ,CD8 alpha chain, CD11b, CD14, CD19, CD20, CD56, ly6G, ter119." [GOC:add, GOC:dsd, GOC:tfm, http://en.wikipedia.org/wiki/Hematopoietic_stem_cell, PMID:19022770] comment: Markers differ between species, and two sets of markers have been described for mice. HSCs are reportedly CD34-positive, CD45-positive, CD48-negative, CD150-positive, CD133-positive, and CD244-negative. subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "blood forming stem cell" EXACT [] synonym: "colony forming unit hematopoietic" RELATED [] @@ -280,6 +286,7 @@ id: CL:0000038 name: erythroid progenitor cell def: "A progenitor cell committed to the erythroid lineage." [GOC:add, ISBN:0721601464] subset: blood_and_immune_upper_slim +subset: cellxgene_subset synonym: "BFU-E" RELATED OMO:0003000 [] synonym: "blast forming unit erythroid" RELATED [] synonym: "burst forming unit erythroid" RELATED [] @@ -311,6 +318,7 @@ id: CL:0000049 name: common myeloid progenitor def: "A progenitor cell committed to myeloid lineage, including the megakaryocyte and erythroid lineages." [GOC:add, ISBN:0878932437, MESH:D023461] comment: This cell type is intended to be compatible with any vertebrate common myeloid progenitor. For mammalian CMP known to be CD34-positive, please use the term 'common myeloid progenitor, CD34-positive' (CL_0001059). +subset: cellxgene_subset subset: human_reference_atlas synonym: "CFU-GEMM" RELATED OMO:0003000 [ISBN:0878932437] synonym: "CFU-S" RELATED OMO:0003000 [ISBN:0878932437] @@ -330,6 +338,7 @@ id: CL:0000050 name: megakaryocyte-erythroid progenitor cell def: "A progenitor cell committed to the megakaryocyte and erythroid lineages." [GOC:add, GOC:dsd, GOC:tfm, http://en.wikipedia.org/wiki/Megakaryocyte-erythroid_progenitor_cell, MESH:D055015, PMID:16647566] comment: MEPs are reportedly CD19-negative, CD34-negative, CD45RA-negative, CD110-positive, CD117-positive, and SCA1-negative and reportedly express the transcription factors GATA-1 and NF-E2. +subset: cellxgene_subset subset: human_reference_atlas synonym: "CFU-EM" EXACT [] synonym: "CFU-MegE" EXACT [] @@ -362,6 +371,7 @@ id: CL:0000055 name: non-terminally differentiated cell def: "A precursor cell with a limited number of potential fates." [SANBI:mhl] comment: define using PATO mulit-potent or oligopotent? +subset: cellxgene_subset synonym: "blast cell" EXACT [] xref: BTO:0000125 xref: FMA:84782 @@ -383,6 +393,7 @@ id: CL:0000057 name: fibroblast def: "A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped." [http://en.wikipedia.org/wiki/Fibroblast, ISBN:0517223651, MESH:D005347] comment: These cells may be vimentin-positive, fibronectin-positive, fsp1-positive, MMP-1-positive, collagen I-positive, collagen III-positive, and alpha-SMA-negative. +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas xref: BTO:0000452 @@ -398,6 +409,7 @@ relationship: present_in_taxon NCBITaxon:9606 id: CL:0000066 name: epithelial cell def: "A cell that is usually found in a two-dimensional sheet with a free surface. The cell has a cytoskeleton that allows for tight cell to cell contact and for cell polarity where apical part is directed towards the lumen and the basal part to the basal lamina." [FB:ma, GOC:tfm, MESH:D004847] +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "epitheliocyte" EXACT [] @@ -416,6 +428,7 @@ property_value: depiction "https://www.swissbiopics.org/api/image/Epithelial_cel id: CL:0000071 name: blood vessel endothelial cell def: "An endothelial cell that lines the vasculature." [GOC:tfm] +subset: cellxgene_subset subset: human_reference_atlas synonym: "cuboidal endothelial cell of vascular tree" EXACT [] is_a: CL:0000076 {is_inferred="true"} ! squamous epithelial cell @@ -430,6 +443,7 @@ relationship: present_in_taxon NCBITaxon:9606 id: CL:0000075 name: columnar/cuboidal epithelial cell def: "A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube." [GO:0002065, https://orcid.org/0000-0001-5208-3432] +subset: cellxgene_subset subset: human_reference_atlas is_a: CL:0000066 ! epithelial cell relationship: present_in_taxon NCBITaxon:9606 @@ -437,6 +451,7 @@ relationship: present_in_taxon NCBITaxon:9606 [Term] id: CL:0000076 name: squamous epithelial cell +subset: cellxgene_subset xref: CALOHA:TS-1249 is_a: CL:0000066 ! epithelial cell @@ -444,6 +459,7 @@ is_a: CL:0000066 ! epithelial cell id: CL:0000077 name: mesothelial cell def: "A flattened epithelial cell of mesenchymal origin that lines the serous cavity." [GOC:tfm, ISBN:0721662544] +subset: cellxgene_subset subset: human_reference_atlas synonym: "mesotheliocyte" EXACT [] xref: FMA:66773 @@ -456,6 +472,7 @@ relationship: present_in_taxon NCBITaxon:9606 id: CL:0000081 name: blood cell def: "A cell found predominately in the blood." [GOC:add, GOC:tfm] +subset: cellxgene_subset subset: general_cell_types_upper_slim xref: FMA:62844 xref: MESH:D001773 @@ -467,6 +484,7 @@ relationship: capable_of GO:0008015 ! blood circulation [Term] id: CL:0000095 name: neuron associated cell +subset: cellxgene_subset is_a: CL:0002319 ! neural cell relationship: develops_from CL:0000133 ! neurectodermal cell @@ -474,6 +492,7 @@ relationship: develops_from CL:0000133 ! neurectodermal cell id: CL:0000099 name: interneuron def: "Most generally any neuron which is not motor or sensory. Interneurons may also refer to neurons whose axons remain within a particular brain region as contrasted with projection neurons which have axons projecting to other brain regions." [GOC:tfm, MESH:D007395] +subset: cellxgene_subset subset: human_reference_atlas xref: BTO:0003811 xref: FBbt:00005125 @@ -501,6 +520,7 @@ id: CL:0000103 name: bipolar neuron def: "A type of interneuron that has two neurites, usually an axon and a dendrite, extending from opposite poles of an ovoid cell body." [GOC:tfm, ISBN:0444009442] subset: BDS_subset +subset: cellxgene_subset xref: FMA:67282 is_a: CL:0000099 ! interneuron intersection_of: CL:0000099 ! interneuron @@ -512,6 +532,7 @@ id: CL:0000115 name: endothelial cell def: "An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal. In mammals, endothelial cell has vimentin filaments and is derived from the mesoderm." [GOC:tfm, http://en.wikipedia.org/wiki/Endothelial_cell, https://sourceforge.net/tracker/?func=detail&atid=440764&aid=3364936&group_id=36855, MESH:D042783, PMID:21275341] comment: From FMA: 9.07.2001: Endothelial cell has always been classified as a kind of epithelial cell, specifically a squamous cell but that is not true. First, endothelial cell can either be squamous or cuboidal (e.g. high-endothelial cell) and secondly, it has different embryological derivation (mesodermal) than a true epithelial cell (ectodermal and endodermal). The basis for present classification is the fact that it comprises the outermost layer or lining of anatomical structures (location-based) but a better structural basis for the differentia is the cytoskeleton of the cell. Endothelial cell has vimentin filaments while an epithelial cell has keratin filaments. [Onard]. +subset: cellxgene_subset subset: human_reference_atlas synonym: "endotheliocyte" EXACT [] xref: BTO:0001176 @@ -531,6 +552,7 @@ relationship: part_of UBERON:0001017 ! central nervous system [Term] id: CL:0000123 name: neuron associated cell (sensu Vertebrata) +subset: cellxgene_subset is_a: CL:0000095 ! neuron associated cell is_a: CL:0000255 ! eukaryotic cell relationship: develops_from CL:0000333 ! migratory neural crest cell @@ -541,6 +563,7 @@ id: CL:0000125 name: glial cell def: "A non-neuronal cell of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu. Guide neuronal migration during development, and exchange metabolites with neurons." [MESH:D009457] comment: Not all glial cells develop from glioblasts, with microglia developing from the mesoderm instead. See https://github.com/obophenotype/cell-ontology/issues/1571 +subset: cellxgene_subset subset: general_cell_types_upper_slim synonym: "neuroglia" RELATED [] synonym: "neuroglial cell" EXACT [] @@ -554,6 +577,7 @@ is_a: CL:0000095 ! neuron associated cell id: CL:0000126 name: macroglial cell def: "A neuroglial cell of ectodermal origin, i.e., the astrocytes and oligodendrocytes considered together." [GOC:tfm, ISBN:0721662544] +subset: cellxgene_subset synonym: "macroglia" RELATED OMO:0003004 [doi:10.1152/physrev.2001.81.2.871] synonym: "macrogliocyte" EXACT [] xref: BTO:0000771 @@ -567,6 +591,7 @@ id: CL:0000127 name: astrocyte def: "A class of large neuroglial (macroglial) cells in the central nervous system - the largest and most numerous neuroglial cells in the brain and spinal cord. Astrocytes (from 'star' cells) are irregularly shaped with many long processes, including those with 'end feet' which form the glial (limiting) membrane and directly and indirectly contribute to the blood-brain barrier. They regulate the extracellular ionic and chemical environment, and 'reactive astrocytes' (along with microglia) respond to injury." [GOC:dsd, GOC:tfm, http://en.wikipedia.org/wiki/Astrocyte, MESH:D001253, PMID:11746784, PMID:12162730, PMID:12898703, PMID:20942978] comment: Astrocytes are reportedly CD68-negative, CD121a-positive, CD184-positive, CD192-positive, CRF-positive, EGFR-positive, GFAP-positive, GLUT1-positive, MBP-negative, and NGFR-positive. +subset: cellxgene_subset subset: human_reference_atlas synonym: "astrocytic glia" EXACT [] xref: BTO:0000099 @@ -579,6 +604,7 @@ relationship: present_in_taxon NCBITaxon:9606 id: CL:0000132 name: corneal endothelial cell def: "An hexagonal, flattened, mitochondria-rich endothelial cell that forms a monolayer on the posterior surface of the cornea (the corneal endothelium). Corneal endothelial cells are derived from the neural crest and are responsible for keeping the cornea transparent by maintaining the tissue in a semi-dry state through the action of their ionic pumps and tight junction barrier." [GOC:tfm, PMID:21976958, PMID:23284695, PMID:34741068, PMID:36769303] +subset: cellxgene_subset subset: eye_upper_slim subset: human_reference_atlas xref: CALOHA:TS-0172 @@ -601,6 +627,7 @@ id: CL:0000134 name: mesenchymal stem cell def: "A connective tissue cell that normally gives rise to other cells that are organized as three-dimensional masses. In humans, this cell type is CD73-positive, CD90-positive, CD105-positive, CD45-negative, CD34-negative, and MHCII-negative. They may further differentiate into osteoblasts, adipocytes, myocytes, neurons, or chondroblasts in vitro. Originally described as residing in the bone marrow, this cell type is now known to reside in many, if not all, adult organs." [FB:ma, GOC:dsd, http://en.wikipedia.org/wiki/Mesenchymal_stem_cell, http://www.copewithcytokines.de/cope.cgi?key=mesenchymal%20stem%20cells, PMCID:PMC2613570, PMID:10102814, PMID:16923606, PMID:17986482, PMID:19960544] comment: Many but not all mesenchymal cells derive from the mesoderm. MSCs are reportedly CD3-negative, CD4-negative, CD5-negative, CD8-negative, CD11a-negative, CD11b-negative, CD14-negative, CD19-negative, CD29-positive, CD31-negative, CD34-negative, CD38-negative, CD40-negative, CD44-positive, CD45-negative, CD49-positive, CD54-positive, CD66b-negative, CD79a-negative, CD80-negative, CD102-positive, CD106-positive, CD117-positive, CD121a-positive, CD121b-positive, CD123-positive, CD124-positive, CD133-negative, CD146-positive, CD166-positive, CD271-positive, B220-negative, Gr1-negative, MHCI-positive, MHCII-negative, SSEA4-negative, sca1-positive, Ter119-negative, and glycophorin A-negative. Cultured MSCs are capable of producing stem cell factor, IL7, IL8, IL11, TGF-beta, cofilin, galectin-1, laminin-receptor 1, cyclophilin A, and MMP-2. +subset: cellxgene_subset synonym: "BMSC" RELATED OMO:0003000 [] synonym: "bone marrow stromal cells" NARROW [] synonym: "CFU-F" RELATED OMO:0003000 [] @@ -633,6 +660,7 @@ is_a: CL:0000325 ! stuff accumulating cell id: CL:0000148 name: melanocyte def: "A pigment cell derived from the neural crest. Contains melanin-filled pigment granules, which gives a brown to black appearance." [SANBI:mhl] +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "melanophore" NARROW [] @@ -659,6 +687,7 @@ is_a: CL:0000147 ! pigment cell id: CL:0000151 name: secretory cell def: "A cell that specializes in controlled release of one or more substances." [GOC:tfm, ISBN:0721662544] +subset: cellxgene_subset xref: BTO:0003659 xref: FMA:86916 is_a: CL:0000000 ! cell @@ -670,12 +699,14 @@ relationship: capable_of GO:0032940 ! secretion by cell id: CL:0000183 name: contractile cell def: "A cell whose primary function is to shorten." [FB:ma] +subset: cellxgene_subset is_a: CL:0000000 ! cell [Term] id: CL:0000187 name: muscle cell def: "A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns." [MESH:D032342] +subset: cellxgene_subset synonym: "muscle fiber" EXACT [] synonym: "myocyte" EXACT [] xref: BTO:0000888 @@ -693,6 +724,7 @@ property_value: depiction "https://www.swissbiopics.org/api/image/Muscle_cells.s id: CL:0000192 name: smooth muscle cell def: "A non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels. They develop from specialized myoblasts (smooth muscle myoblast)." [http://en.wikipedia.org/wiki/Smooth_muscle_cell, MESH:D032389, PMID:9315361] +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "myocytes, smooth muscle" EXACT [MESH:D032389] @@ -724,6 +756,7 @@ relationship: part_of UBERON:0001032 ! sensory system id: CL:0000210 name: photoreceptor cell def: "A cell specialized to detect and transduce light." [MESH:D010786] +subset: cellxgene_subset xref: BTO:0001060 xref: CALOHA:TS-0868 xref: FMA:86740 @@ -774,6 +807,7 @@ relationship: part_of UBERON:0000924 ! ectoderm id: CL:0000222 name: mesodermal cell def: "A cell of the middle germ layer of the embryo." [MESH:D008648] +subset: cellxgene_subset synonym: "mesoblast" EXACT [] synonym: "mesoderm cell" EXACT [] xref: FMA:72554 @@ -794,6 +828,7 @@ id: CL:0000232 name: erythrocyte def: "A red blood cell. In mammals, mature erythrocytes are biconcave disks containing hemoglobin whose function is to transport oxygen." [GOC:tfm, MESH:D004912] subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "RBC" EXACT [] synonym: "red blood cell" EXACT [] @@ -818,6 +853,7 @@ relationship: present_in_taxon NCBITaxon:9606 [Term] id: CL:0000255 name: eukaryotic cell +subset: cellxgene_subset xref: MESH:D005057 is_a: CL:0000000 ! cell intersection_of: CL:0000000 ! cell @@ -827,6 +863,7 @@ relationship: only_in_taxon NCBITaxon:2759 ! Eukaryota [Term] id: CL:0000287 name: eye photoreceptor cell +subset: cellxgene_subset subset: eye_upper_slim subset: human_reference_atlas is_a: CL:0000210 ! photoreceptor cell @@ -968,13 +1005,14 @@ is_a: CL:0000211 ! electrically active cell id: CL:0000514 name: smooth muscle myoblast def: "A precursor cell destined to differentiate into smooth muscle myocytes." [GOC:tfm, MESH:D032390] +subset: cellxgene_subset synonym: "myoblast, smooth muscle" EXACT [MESH:D032390] synonym: "satellite cell" RELATED [] xref: FMA:84798 is_a: CL:0000056 ! myoblast intersection_of: CL:0000056 ! myoblast -intersection_of: RO:0002203 CL:0000192 ! develops into smooth muscle cell -relationship: RO:0002203 CL:0000192 ! develops into smooth muscle cell +intersection_of: develops_into CL:0000192 ! smooth muscle cell +relationship: develops_into CL:0000192 ! smooth muscle cell [Term] id: CL:0000526 @@ -989,6 +1027,7 @@ relationship: present_in_taxon NCBITaxon:9606 [Term] id: CL:0000529 name: pigmented epithelial cell +subset: cellxgene_subset is_a: CL:0000710 ! neurecto-epithelial cell [Term] @@ -996,6 +1035,7 @@ id: CL:0000540 name: neuron def: "The basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system." [http://en.wikipedia.org/wiki/Neuron, MESH:D009474] comment: These cells are also reportedly CD4-negative and CD200-positive. They are also capable of producing CD40L and IFN-gamma. +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "nerve cell" EXACT [] @@ -1028,6 +1068,7 @@ id: CL:0000547 name: proerythroblast def: "An immature, nucleated erythrocyte occupying the stage of erythropoeisis that follows formation of erythroid progenitor cells. This cell is CD71-positive, has both a nucleus and a nucleolus, and lacks hematopoeitic lineage markers." [ISBN:0721601464, PMID:1638021] subset: blood_and_immune_upper_slim +subset: cellxgene_subset synonym: "pronormoblast" RELATED [] synonym: "rubriblast" EXACT [ISBN:0721601464] xref: FMA:83518 @@ -1036,6 +1077,7 @@ is_a: CL:0002242 ! nucleate cell is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000764 ! erythroid lineage cell intersection_of: bearer_of PATO:0002505 ! nucleated +intersection_of: bearer_of PATO:0040072 ! high nuclear/cytoplasmic ratio intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M @@ -1048,9 +1090,9 @@ intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell sur intersection_of: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule intersection_of: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G intersection_of: has_part CL:0017503 ! basophilic cytoplasm -intersection_of: has_part CL:0017505 ! increased nucleus size intersection_of: has_part GO:0005730 ! nucleolus intersection_of: RO:0002104 PR:000001945 ! has plasma membrane part transferrin receptor protein 1 +relationship: bearer_of PATO:0040072 ! high nuclear/cytoplasmic ratio relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M @@ -1064,7 +1106,6 @@ relationship: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule relationship: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G relationship: develops_from CL:0000038 ! erythroid progenitor cell relationship: has_part CL:0017503 ! basophilic cytoplasm -relationship: has_part CL:0017505 ! increased nucleus size relationship: has_part GO:0005730 ! nucleolus relationship: RO:0002104 PR:000001945 ! has plasma membrane part transferrin receptor protein 1 @@ -1132,6 +1173,7 @@ id: CL:0000553 name: megakaryocyte progenitor cell def: "The earliest cytologically identifiable precursor in the thrombocytic series. This cell is capable of endomitosis and lacks expression of hematopoieitic lineage markers (lin-negative)." [GOC:dsd, GOC:tfm, ISBN:0721601464] comment: Lineage negative is described here as CD2-negative, CD3-negative, CD4-negative, CD5-negative, CD8a-negative, CD14-negative, CD19-negative, CD20-negative, CD56-negative, Ly6g-negative, and Ter119-negative. +subset: cellxgene_subset subset: human_reference_atlas synonym: "CFU-Meg" EXACT [PMID:11722431, PMID:12482498] synonym: "colony-forming unit-megakaryocyte" EXACT [] @@ -1187,6 +1229,7 @@ name: megakaryocyte def: "A large hematopoietic cell (50 to 100 micron) with a lobated nucleus. Once mature, this cell undergoes multiple rounds of endomitosis and cytoplasmic restructuring to allow platelet formation and release." [http://en.wikipedia.org/wiki/Megakaryocyte, ISBN:0721601464, MESH:D008533, PMID:31043076] comment: Megakaryocytes are reportedly CD181-positive and CD182-positive. subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "megacaryocyte" EXACT [] synonym: "megalocaryocyte" EXACT [] @@ -1205,6 +1248,7 @@ id: CL:0000558 name: reticulocyte def: "An immature erythrocyte that changes the protein composition of its plasma membrane by exosome formation and extrusion. The types of protein removed differ between species though removal of the transferrin receptor is apparent in mammals and birds." [GOC:add, GOC:tfm, PMID:15946868, PMID:2037622] subset: blood_and_immune_upper_slim +subset: cellxgene_subset xref: BTO:0001173 xref: CALOHA:TS-0864 xref: MESH:D012156 @@ -1243,6 +1287,7 @@ relationship: RO:0002104 PR:000001945 ! has plasma membrane part transferrin rec id: CL:0000561 name: amacrine cell def: "Interneuron of the vertebrate retina. They integrate, modulate, and interpose a temporal domain in the visual message presented to the retinal ganglion cells, with which they synapse in the inner plexiform layer. They lack large axons." [GOC:tfm, MESH:D025042, WikipediaVersioned:Amacrine_cell&oldid=1023572246] +subset: cellxgene_subset subset: eye_upper_slim subset: human_reference_atlas synonym: "AC" RELATED OMO:0003000 [doi:10.1038/s41598-020-66092-9] @@ -1280,6 +1325,7 @@ relationship: RO:0002104 PR:000016043 ! has plasma membrane part T-cell acute ly id: CL:0000573 name: retinal cone cell def: "One of the two photoreceptor cell types in the vertebrate retina. In cones the photopigment is in invaginations of the cell membrane of the outer segment. Cones are less sensitive to light than rods, but they provide vision with higher spatial and temporal acuity, and the combination of signals from cones with different pigments allows color vision." [MESH:D017949] +subset: cellxgene_subset subset: human_reference_atlas synonym: "cone" RELATED [doi:10.1038/s41598-020-66092-9] xref: BTO:0001036 @@ -1293,6 +1339,7 @@ relationship: present_in_taxon NCBITaxon:9606 id: CL:0000575 name: corneal epithelial cell def: "An epithelial cell of the cornea." [GOC:tfm] +subset: cellxgene_subset subset: eye_upper_slim subset: human_reference_atlas synonym: "epithelial cell of cornea" EXACT [FMA:70551] @@ -1310,6 +1357,7 @@ relationship: present_in_taxon NCBITaxon:9606 id: CL:0000604 name: retinal rod cell def: "One of the two photoreceptor cell types of the vertebrate retina. In rods the photopigment is in stacks of membranous disks separate from the outer cell membrane. Rods are more sensitive to light than cones, but rod mediated vision has less spatial and temporal resolution than cone vision." [MESH:D017948] +subset: cellxgene_subset subset: human_reference_atlas synonym: "rod" RELATED [doi:10.1038/s41598-020-66092-9] xref: BTO:0001024 @@ -1323,6 +1371,7 @@ relationship: present_in_taxon NCBITaxon:9606 id: CL:0000636 name: Mueller cell def: "Astrocyte-like radial glial cell that extends vertically throughout the retina, with the nucleus are usually in the middle of the inner nuclear layer." [GOC:NV, PMID:21911394] +subset: cellxgene_subset subset: eye_upper_slim subset: human_reference_atlas synonym: "Muller cell" EXACT MISSPELLING [doi:10.21769/BioProtoc.4179] @@ -1338,6 +1387,7 @@ relationship: present_in_taxon NCBITaxon:9606 id: CL:0000679 name: glutamatergic neuron def: "A neuron that is capable of some neurotansmission by glutamate secretion." [] +subset: cellxgene_subset subset: human_reference_atlas xref: FBbt:00100291 xref: WBbt:0006829 @@ -1352,17 +1402,19 @@ relationship: present_in_taxon NCBITaxon:9606 id: CL:0000680 name: muscle precursor cell def: "A non-terminally differentiated cell that is capable of developing into a muscle cell." [GOC:add] +subset: cellxgene_subset is_a: CL:0000055 ! non-terminally differentiated cell intersection_of: CL:0011115 ! precursor cell -intersection_of: RO:0002203 CL:0000187 ! develops into muscle cell +intersection_of: develops_into CL:0000187 ! muscle cell relationship: develops_from CL:0000222 ! mesodermal cell -relationship: RO:0002203 CL:0000187 ! develops into muscle cell +relationship: develops_into CL:0000187 ! muscle cell [Term] id: CL:0000681 name: radial glial cell def: "A cell present in the developing CNS. Functions as both a precursor cell and as a scaffold to support neuronal migration." [GOC:dph] comment: Unlike that of mammals, the brain of adult teleost fish exhibits an intense and widespread neurogenic activity as a result of the persistence of\nradial glial cells acting as neural progenitors throughout life. +subset: cellxgene_subset synonym: "forebrain radial glial cell" NARROW [] is_a: CL:0000125 ! glial cell relationship: develops_from CL:0000710 ! neurecto-epithelial cell @@ -1396,6 +1448,7 @@ relationship: capable_of GO:0048103 ! somatic stem cell division id: CL:0000740 name: retinal ganglion cell def: "The set of neurons that receives neural inputs via bipolar, horizontal and amacrine cells. The axons of these cells make up the optic nerve." [GOC:dph] +subset: cellxgene_subset subset: eye_upper_slim subset: human_reference_atlas synonym: "gangliocyte" EXACT [] @@ -1413,6 +1466,7 @@ relationship: RO:0002100 UBERON:0000966 ! has soma location retina id: CL:0000745 name: retina horizontal cell def: "A neuron that laterally connects other neurons in the inner nuclear layer of the retina." [ISBN:0195088433] +subset: cellxgene_subset subset: eye_upper_slim subset: human_reference_atlas synonym: "HC" RELATED OMO:0003000 [doi:10.1038/s41598-020-66092-9] @@ -1427,6 +1481,7 @@ relationship: RO:0002100 UBERON:0003902 ! has soma location retinal neural layer id: CL:0000748 name: retinal bipolar neuron def: "A bipolar neuron found in the retina and having connections with photoreceptors cells and neurons in the inner plexiform layer." [PMID:14689473] +subset: cellxgene_subset subset: eye_upper_slim subset: human_reference_atlas synonym: "BC" RELATED OMO:0003000 [doi:10.1038/s41598-020-66092-9] @@ -1445,6 +1500,7 @@ relationship: RO:0002100 UBERON:0001791 ! has soma location inner nuclear layer id: CL:0000763 name: myeloid cell def: "A cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage." [GOC:add] +subset: cellxgene_subset xref: BTO:0001441 xref: CALOHA:TS-0647 xref: MESH:D022423 @@ -1458,6 +1514,7 @@ id: CL:0000764 name: erythroid lineage cell def: "A immature or mature cell in the lineage leading to and including erythrocytes." [GOC:add, GOC:tfm] comment: Note that in FMA erythropoietic cells are types of nucleated erythrocytes and thus don't include erythrocytes. +subset: cellxgene_subset subset: human_reference_atlas synonym: "erythropoietic cell" EXACT [] xref: CALOHA:TS-0290 @@ -1471,6 +1528,7 @@ id: CL:0000765 name: erythroblast def: "A nucleated precursor of an erythrocyte that lacks hematopoietic lineage markers." [GOC:add, ISBN:0721601464, PMID:18174176] subset: blood_and_immune_upper_slim +subset: cellxgene_subset synonym: "normoblast" EXACT [] xref: BTO:0001571 xref: CALOHA:TS-0289 @@ -1515,6 +1573,7 @@ name: hematopoietic multipotent progenitor cell def: "A hematopoietic multipotent progenitor cell is multipotent, but not capable of long-term self-renewal. These cells are characterized as lacking lineage cell surface markers and being CD34-positive in both mice and humans." [GOC:add, GOC:tfm, PMID:19022770] comment: Markers differ between mouse and human. subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "hemopoietic progenitor cell" EXACT [] synonym: "MPP" EXACT [] @@ -1562,6 +1621,7 @@ id: CL:0000839 name: myeloid lineage restricted progenitor cell def: "A progenitor cell restricted to the myeloid lineage." [GOC:add, GOC:tfm, PMID:19022770] comment: Note that this is a class of cell types, not an identified single cell type. +subset: cellxgene_subset subset: human_reference_atlas synonym: "myeloid progenitor cell" BROAD [] xref: BTO:0004730 @@ -1578,6 +1638,7 @@ relationship: present_in_taxon NCBITaxon:9606 id: CL:0000988 name: hematopoietic cell def: "A cell of a hematopoietic lineage." [GO_REF:0000031, GOC:add] +subset: cellxgene_subset synonym: "haematopoietic cell" EXACT [] synonym: "haemopoietic cell" EXACT [] synonym: "hemopoietic cell" EXACT [] @@ -1645,6 +1706,7 @@ id: CL:0002139 name: endothelial cell of vascular tree def: "An endothelial cell of the vascular tree, which includes blood vessels and lymphatic vessels." [GOC:dsd, GOC:tfm, PMID:12768659] comment: These cells are reportedly CD31-positive, CD34-positive, CD144-positive, TAL1-positive. +subset: cellxgene_subset synonym: "cubodial endothelial cell of vascular tree" NARROW [] synonym: "vascular endothelial cell" EXACT [] xref: BTO:0001854 @@ -1692,6 +1754,7 @@ id: CL:0002303 name: pigmented ciliary epithelial cell def: "A cell that is part of pigmented ciliary epithelium. This cell type uptakes sodium and chloride ions from stromal interstitium and passes the ions to non-pigmented ciliary epithelial cells via gap junctions." [PMID:15106942] comment: In a consensus model of unidirectional secretion, aqueous humour is formed by transferring solute, principally NaCl, from stroma to posterior chamber, with water passively following the osmotic gradient. Unidirectional secretion comprises three sequential steps. First, NaCl is transferred from the stromal interstitium into the pigmented ciliary epithelial (PE) cells. Second, solute passes from the PE into the non-pigmented ciliary epithelial (NPE) cells through gap junctions. Finally, NPE cells release Na+ and Cl− into the aqueous humour. {xref="https://doi.org/10.1016/j.exer.2003.09.021"} +subset: cellxgene_subset subset: eye_upper_slim subset: human_reference_atlas synonym: "PE cell" EXACT [https://doi.org/10.1016/j.exer.2003.09.021] @@ -1707,6 +1770,7 @@ id: CL:0002304 name: non-pigmented ciliary epithelial cell def: "A cell that is part of non-pigmented ciliary epithelium. This cell type participates in aqueous humor formation by releasing solute, principally sodium and chloride ions received from pigmented epithelial cells via gap junctions, into the aqueous humor of the eye." [GOC:tfm, PMID:15106942] comment: In a consensus model of unidirectional secretion, aqueous humour is formed by transferring solute, principally NaCl, from stroma to posterior chamber, with water passively following the osmotic gradient. Unidirectional secretion comprises three sequential steps. First, NaCl is transferred from the stromal interstitium into the pigmented ciliary epithelial (PE) cells. Second, solute passes from the PE into the non-pigmented ciliary epithelial (NPE) cells through gap junctions. Finally, NPE cells release Na+ and Cl− into the aqueous humour. {xref="https://doi.org/10.1016/j.exer.2003.09.021"} +subset: cellxgene_subset subset: eye_upper_slim subset: human_reference_atlas synonym: "nonpigmented ciliary epithelial cell" EXACT [PMID:10913011] @@ -1722,6 +1786,7 @@ creation_date: 2010-09-13T04:09:31Z id: CL:0002319 name: neural cell def: "A cell that is part of the nervous system." [GOC:tfm, ISBN:0618947256] +subset: cellxgene_subset xref: CALOHA:TS-2040 xref: FMA:70333 is_a: CL:0000000 ! cell @@ -1735,6 +1800,7 @@ creation_date: 2010-09-15T01:34:57Z id: CL:0002320 name: connective tissue cell def: "A cell of the supporting or framework tissue of the body, arising chiefly from the embryonic mesoderm and including adipose tissue, cartilage, and bone." [GOC:tfm, ISBN:0618947256] +subset: cellxgene_subset xref: CALOHA:TS-2096 xref: FMA:63875 xref: MESH:D003239 @@ -1760,6 +1826,7 @@ creation_date: 2010-09-15T03:39:21Z id: CL:0002363 name: keratocyte def: "A keratocyte is a specialized fibroblast residing in the cornea stroma that has a flattened, dendritic morphology; located between the lamellae with a large flattened nucleus, and lengthy processes which communicate with neighboring cells. This corneal layer, representing about 85-90% of corneal thickness, is built up from highly regular collagenous lamellae and extracellular matrix components. Keratocytes play the major role in keeping it transparent, healing its wounds, and synthesizing its components. This cell type secretes collagen I, V, VI, and keratan sulfate." [GOC:tfm, ISBN:9780702029585] +subset: cellxgene_subset subset: eye_upper_slim subset: human_reference_atlas synonym: "corneal fibroblast" EXACT [] @@ -1830,6 +1897,7 @@ creation_date: 2011-03-01T05:28:52Z id: CL:0002585 name: retinal blood vessel endothelial cell def: "A blood vessel endothelial cell that is part of the retina." [GOC:tfm] +subset: cellxgene_subset subset: eye_upper_slim subset: human_reference_atlas is_a: CL:0000071 {is_inferred="true"} ! blood vessel endothelial cell @@ -1845,6 +1913,7 @@ creation_date: 2011-03-06T03:28:27Z id: CL:0002586 name: retinal pigment epithelial cell def: "An epithelial cell of the retinal pigmented epithelium." [GOC:tfm] +subset: cellxgene_subset subset: eye_upper_slim subset: human_reference_atlas xref: BTO:0004910 @@ -1899,6 +1968,7 @@ is_a: CL:0000187 ! muscle cell id: CL:0008001 name: hematopoietic precursor cell def: "Any hematopoietic cell that is a precursor of some other hematopoietic cell type." [GOC:dos] +subset: cellxgene_subset is_a: CL:0000988 ! hematopoietic cell [Term] @@ -1915,6 +1985,7 @@ relationship: part_of UBERON:8600004 ! visceral muscle tissue id: CL:0008019 name: mesenchymal cell def: "A non-polarised cell precursor cell that is part of some mesenchyme, is associated with the cell matrix but is not connected to other cells and is capable of migration." [] +subset: cellxgene_subset subset: human_reference_atlas synonym: "mesenchyme cell" EXACT [] is_a: CL:0000219 ! motile cell @@ -1964,6 +2035,7 @@ relationship: seeAlso https://github.com/obophenotype/cell-ontology/issues/786 id: CL:0011012 name: neural crest cell def: "A cell of the neural crest. Neural crest cells are multipotent. Premigratory neural crest cells are found at the neural plate boarder, some of which will undergo ectomesynchymal transition and delamination to form migratory neural crest cells." [https://orcid.org/0000-0001-5208-3432, https://orcid.org/0000-0002-9900-7880] +subset: cellxgene_subset is_a: CL:0000048 ! multi fate stem cell is_a: CL:0002321 ! embryonic cell (metazoa) @@ -1971,6 +2043,7 @@ is_a: CL:0002321 ! embryonic cell (metazoa) id: CL:0011026 name: progenitor cell def: "A precursor cell that has a tendency to differentiate into a specific type of cell. They are descendants of stem cells, only they are more constrained in their differentiation potential or capacity for self-renewal, and are often more limited in both senses." [https://doi.org/10.1016/B978-0-12-409503-8.00002-0, ISBN:978-1-62808-994-3] +subset: cellxgene_subset is_a: CL:0011115 ! precursor cell intersection_of: CL:0011115 ! precursor cell intersection_of: develops_from CL:0000034 ! stem cell @@ -1992,6 +2065,7 @@ id: CL:0011115 name: precursor cell def: "A cell that, by division or terminal differentiation, can give rise to other cell types." [GOC:dos] comment: Work is needed on GO 'cell differentiation' before it is clear whether the equivalent class definition 'native cell' that capable_of some 'cell differentiation' works. Also, may want to consider merging this with non-terminally differentiated cell. +subset: cellxgene_subset is_a: CL:0000000 ! cell intersection_of: CL:0000000 ! cell intersection_of: capable_of GO:0030154 ! cell differentiation @@ -2031,21 +2105,11 @@ relationship: bearer_of PATO:0070047 ! polychromatophilic relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2009-12-28T04:25:23Z -[Term] -id: CL:0017505 -name: increased nucleus size -def: "A nucleus size quality which is relatively high compared to the amount of cytoplasm present in the same cell." [GOC:tfm] -is_a: GO:0005634 ! nucleus -intersection_of: GO:0005634 ! nucleus -intersection_of: bearer_of PATO:0000586 ! increased size -relationship: bearer_of PATO:0000586 ! increased size -relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 -creation_date: 2009-12-23T10:53:24Z - [Term] id: CL:1000432 name: conjunctival epithelial cell def: "An epithelial cell that is part of the conjunctiva." [GOC:tfm] +subset: cellxgene_subset subset: eye_upper_slim synonym: "epithelial cell of conjunctiva" EXACT [FMA:70552] xref: FMA:70552 @@ -2058,6 +2122,7 @@ relationship: part_of UBERON:0001811 ! conjunctiva id: CL:1000443 name: ciliary muscle cell def: "A smooth muscle cell that is part of the ciliary body." [GOC:tfm] +subset: cellxgene_subset subset: eye_upper_slim synonym: "smooth muscle cell of ciliary body" EXACT [FMA:70610] xref: FMA:70610 @@ -2368,7 +2433,7 @@ id: GO:0005575 name: cellular_component namespace: cellular_component alt_id: GO:0008372 -def: "A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex)." [GOC:pdt] +def: "A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex)." [GOC:pdt] comment: Note that, in addition to forming the root of the cellular component ontology, this term is recommended for the annotation of gene products whose cellular component is unknown. When this term is used for annotation, it indicates that no information was available about the cellular component of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this. subset: goslim_candida subset: goslim_chembl @@ -2399,8 +2464,8 @@ subset: goslim_metagenomics subset: goslim_mouse subset: goslim_pir subset: goslim_plant +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset synonym: "extracellular" EXACT [] xref: Wikipedia:Extracellular is_a: GO:0110165 ! cellular anatomical entity @@ -2459,7 +2524,7 @@ comment: Note that for multicellular organisms, the extracellular space refers t subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "intercellular space" RELATED [] xref: NIF_Subcellular:sao1425028079 is_a: GO:0110165 ! cellular anatomical entity @@ -2523,8 +2588,8 @@ subset: goslim_flybase_ribbon subset: goslim_generic subset: goslim_metagenomics subset: goslim_pir +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset synonym: "chromatid" RELATED [] synonym: "interphase chromosome" NARROW [] synonym: "prophase chromosome" NARROW [] @@ -2558,8 +2623,8 @@ subset: goslim_chembl subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset xref: Wikipedia:Cytoplasm is_a: GO:0110165 ! cellular anatomical entity relationship: part_of GO:0005622 ! intracellular anatomical structure @@ -2577,8 +2642,8 @@ subset: goslim_generic subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset synonym: "free ribosome" NARROW [NIF_Subcellular:sao1139385046] synonym: "membrane bound ribosome" NARROW [NIF_Subcellular:sao1291545653] synonym: "ribosomal RNA" RELATED [] @@ -2603,8 +2668,8 @@ subset: goslim_generic subset: goslim_metagenomics subset: goslim_mouse subset: goslim_plant +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset synonym: "bacterial inner membrane" NARROW [] synonym: "cell membrane" EXACT [] synonym: "cellular membrane" EXACT [NIF_Subcellular:sao6433132645] @@ -2646,7 +2711,7 @@ subset: goslim_drosophila subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "protein anabolism" EXACT [] synonym: "protein biosynthesis" EXACT [] synonym: "protein biosynthetic process" EXACT [] @@ -2718,7 +2783,7 @@ subset: goslim_chembl subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "single-organism transport" RELATED [] is_a: GO:0051234 ! establishment of localization property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20292" xsd:anyURI @@ -3134,7 +3199,7 @@ id: GO:0008219 name: cell death namespace: biological_process def: "Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538)." [GOC:mah, GOC:mtg_apoptosis, PMID:25236395] -comment: This term should not be used for direct annotation, it is currently kept in GO as a placeholder for describing cell death phenotypes in uPHENO. When information is provided on a programmed cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'). Unintentional cell death, i.e. cell death caused by injury, ageing, or cell phenotypes observed as a result of a pathological mutation in an essential gene should NOT be annotated using GO terms. +comment: This term should not be used for direct annotation, it is currently kept in GO as a placeholder for describing cell death phenotypes in uPHENO. When information is provided on a programmed cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'). Unintentional cell death, i.e. cell death caused by injury, ageing, or cell phenotypes observed as a result of a pathological mutation in an essential gene should NOT be annotated using GO terms. subset: gocheck_do_not_annotate synonym: "accidental cell death" RELATED [] synonym: "necrosis" RELATED [] @@ -3373,7 +3438,7 @@ subset: goslim_drosophila subset: goslim_generic subset: goslim_mouse subset: goslim_plant -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "caspase-independent apoptosis" RELATED [] synonym: "caspase-independent cell death" NARROW [] synonym: "non-apoptotic programmed cell death" NARROW [] @@ -3652,8 +3717,8 @@ subset: goslim_flybase_ribbon subset: goslim_generic subset: goslim_mouse subset: goslim_pombe +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset synonym: "biological signaling" EXACT [] synonym: "signaling process" EXACT [] synonym: "signalling" EXACT [] @@ -3680,7 +3745,7 @@ id: GO:0030030 name: cell projection organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon." [GOC:jl, GOC:mah, http://www.cogsci.princeton.edu/~wn/] -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "cell projection organisation" EXACT [] synonym: "cell projection organization and biogenesis" RELATED [GOC:mah] synonym: "cell surface structure organization and biogenesis" RELATED [GOC:mah] @@ -3860,7 +3925,7 @@ subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_pir -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "matrisome" NARROW [] synonym: "proteinaceous extracellular matrix" EXACT [] xref: NIF_Subcellular:nlx_subcell_20090513 @@ -4184,7 +4249,7 @@ subset: goslim_agr subset: goslim_flybase_ribbon subset: goslim_mouse subset: goslim_pir -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "cell process" BROAD [] synonym: "cellular process" BROAD [] synonym: "cellular projection" EXACT [] @@ -4242,12 +4307,14 @@ alt_id: GO:0034960 alt_id: GO:0043283 alt_id: GO:0044259 def: "The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:mah] +subset: gocheck_do_not_annotate subset: goslim_pir synonym: "biopolymer metabolic process" EXACT [GOC:mtg_chebi_dec09] synonym: "macromolecule metabolism" EXACT [] synonym: "multicellular organismal macromolecule metabolic process" NARROW [] synonym: "organismal macromolecule metabolism" EXACT [] is_a: GO:0008152 ! metabolic process +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI [Term] id: GO:0043209 @@ -4273,7 +4340,7 @@ def: "Organized structure of distinctive morphology and function. Includes the n subset: goslim_chembl subset: goslim_generic subset: goslim_pir -subset: prokaryote_subset +subset: goslim_prokaryote xref: NIF_Subcellular:sao1539965131 xref: Wikipedia:Organelle is_a: GO:0110165 ! cellular anatomical entity @@ -4455,9 +4522,11 @@ id: GO:0044238 name: primary metabolic process namespace: biological_process def: "The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism." [GOC:go_curators, http://www.metacyc.org] +subset: gocheck_do_not_annotate subset: goslim_pir synonym: "primary metabolism" EXACT [] is_a: GO:0008152 ! metabolic process +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI [Term] id: GO:0044249 @@ -4643,6 +4712,7 @@ id: GO:0048856 name: anatomical structure development namespace: biological_process def: "The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome." [GO_REF:0000021] +subset: gocheck_do_not_annotate subset: goslim_chembl subset: goslim_generic subset: goslim_plant @@ -4651,6 +4721,7 @@ is_a: GO:0032502 ! developmental process intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of UBERON:0000061 ! anatomical structure relationship: results_in_development_of UBERON:0000061 ! anatomical structure +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI [Term] id: GO:0048869 @@ -4668,7 +4739,7 @@ def: "Any process involved in the controlled self-propelled movement of a cell t subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "cell locomotion" EXACT [] synonym: "cell movement" RELATED [] synonym: "movement of a cell" EXACT [] @@ -4754,7 +4825,7 @@ subset: goslim_agr subset: goslim_flybase_ribbon subset: goslim_mouse subset: goslim_pir -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "physiological response to stimulus" EXACT [] is_a: GO:0008150 ! biological_process @@ -5081,7 +5152,7 @@ subset: goslim_generic subset: goslim_metagenomics subset: goslim_pir subset: goslim_pombe -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "cellular macromolecule complex assembly" RELATED [] synonym: "cellular protein complex assembly" EXACT [] synonym: "cellular protein-containing complex assembly" RELATED [] @@ -5165,10 +5236,12 @@ id: GO:0071704 name: organic substance metabolic process namespace: biological_process def: "The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon." [GOC:mah] +subset: gocheck_do_not_annotate synonym: "organic molecular entity metabolic process" EXACT [] synonym: "organic molecular entity metabolism" EXACT [] synonym: "organic substance metabolism" EXACT [] is_a: GO:0008152 ! metabolic process +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI created_by: mah creation_date: 2010-03-08T03:32:18Z @@ -5208,7 +5281,7 @@ creation_date: 2010-09-10T01:39:16Z id: GO:0071944 name: cell periphery namespace: cellular_component -def: "The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures." [GOC:pdt] +def: "The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures." [GOC:pdt] subset: goslim_flybase_ribbon is_a: GO:0110165 ! cellular anatomical entity created_by: mah @@ -5509,6 +5582,7 @@ subset: goslim_pir is_a: GO:0005575 ! cellular_component is_a: UBERON:0000061 ! anatomical structure property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24200" xsd:anyURI +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI created_by: kmv creation_date: 2019-08-12T18:01:37Z @@ -6018,30 +6092,6 @@ subset: attribute_slim synonym: "relational shape quality" EXACT [] is_a: PATO:0000051 ! morphology -[Term] -id: PATO:0000068 -name: qualitative -namespace: quality -comment: TODO: define this or obsolete it and move children somewhere else. -is_a: PATO:0000001 ! quality - -[Term] -id: PATO:0000069 -name: deviation (from_normal) -namespace: quality -def: "A quality inhering in a bearer by virtue of the whether the bearer differs from normal or average." [PATOC:GVG] -subset: attribute_slim -is_a: PATO:0000068 ! qualitative - -[Term] -id: PATO:0000117 -name: size -namespace: quality -def: "A morphology quality inhering in a bearer by virtue of the bearer's physical magnitude." [WordNet:WordNet] -subset: attribute_slim -subset: scalar_slim -is_a: PATO:0000051 ! morphology - [Term] id: PATO:0000136 name: closure @@ -6086,36 +6136,6 @@ synonym: "round" RELATED [] synonym: "rounded" RELATED [] is_a: PATO:0000947 ! elliptic -[Term] -id: PATO:0000461 -name: normal -namespace: quality -def: "A quality inhering in a bearer by virtue of the bearer's exhibiting no deviation from normal or average." [PATOC:GVG] -subset: abnormal_slim -subset: mpath_slim -subset: value_slim -synonym: "average" RELATED [] -is_a: PATO:0000068 ! qualitative -property_value: RO:0002604 PATO:0000460 - -[Term] -id: PATO:0000586 -name: increased size -namespace: quality -alt_id: PATO:0001202 -def: "A size quality which is relatively high." [PATOC:GVG] -subset: value_slim -synonym: "big" RELATED [] -synonym: "enlarged" RELATED [] -synonym: "expanded" RELATED [] -synonym: "great" RELATED [] -synonym: "large" RELATED [] -is_a: PATO:0000117 ! size -is_a: PATO:0002305 ! increased object quality -intersection_of: PATO:0000117 ! size -intersection_of: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal -property_value: RO:0002604 PATO:0000587 - [Term] id: PATO:0000608 name: closed @@ -6507,32 +6527,6 @@ is_a: PATO:0002078 ! hollow relationship: dc-contributor https://orcid.org/0000-0002-2061-091X creation_date: 2011-06-08T06:33:50Z -[Term] -id: PATO:0002300 -name: increased quality -namespace: quality -def: "A quality that has a value that is increased compared to normal or average." [PATOC:GVG] -is_a: PATO:0000069 ! deviation (from_normal) -intersection_of: PATO:0000001 ! quality -intersection_of: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal -relationship: dc-contributor https://orcid.org/0000-0002-2061-091X -relationship: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal -property_value: RO:0002604 PATO:0002301 -creation_date: 2011-06-16T06:39:43Z - -[Term] -id: PATO:0002305 -name: increased object quality -namespace: quality -def: "A quality of an object that has a value that is increased compared to normal or average." [PATOC:GVG] -is_a: PATO:0001241 ! physical object quality -is_a: PATO:0002300 ! increased quality -intersection_of: PATO:0001241 ! physical object quality -intersection_of: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal -relationship: dc-contributor https://orcid.org/0000-0002-2061-091X -property_value: RO:0002604 PATO:0002303 -creation_date: 2011-06-16T06:54:01Z - [Term] id: PATO:0002309 name: fiber shaped @@ -6606,6 +6600,16 @@ comment: A complete coverage of this domain would subclasses homopolymeric, copo subset: value_slim is_a: PATO:0000141 ! structure +[Term] +id: PATO:0040072 +name: high nuclear/cytoplasmic ratio +namespace: quality +def: "A quality inhering in a cell by virtue of the cell having a high nuclear/cytoplasmic ratio." [http://lymerick.net/blood-cells.pdf, Wikipedia:NC_ratio&oldid=931936284] +comment: A high nuclear/cytolasmic ratio is 70% or higher. +synonym: "high N:C ratio" EXACT [] +is_a: PATO:0001396 ! cellular quality +created_by: http://orcid.org/0000-0001-5208-3432 + [Term] id: PATO:0070006 name: cortical bipolar morphology @@ -7097,7 +7101,7 @@ synonym: "eye" BROAD [FMA:54448] synonym: "eyes" RELATED OMO:0003004 [TAO:0000107] synonym: "orbital part of face" RELATED [FMA:54448] synonym: "orbital region" RELATED [FMA:54448] -synonym: "regio orbitalis" EXACT LATIN [FMA:54448, FMA:TA] +synonym: "regio orbitalis" EXACT OMO:0003011 [FMA:54448, FMA:TA] synonym: "vertebrate eye" NARROW [] xref: AAO:0010340 xref: BIRNLEX:1169 @@ -7152,7 +7156,7 @@ xref: CALOHA:TS-2043 xref: EHDAA2:0001824 xref: EHDAA:500 xref: EMAPA:35955 -xref: FBbt:00005155 +xref: FBbt:00005155 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: GAID:63 xref: HAO:0000930 xref: MA:0000017 @@ -7241,7 +7245,7 @@ def: "Multi-tissue structure that is comprised of a secretory epithelial layer ( subset: uberon_slim subset: vertebrate_core synonym: "serosa" RELATED [Wikipedia:Serous_membrane] -synonym: "tunica serosa" EXACT LATIN [FMA:9581] +synonym: "tunica serosa" EXACT OMO:0003011 [FMA:9581] synonym: "wall of serous sac" EXACT [FMA:9581] xref: FMA:9581 xref: GAID:19 @@ -7320,7 +7324,7 @@ xref: BILA:0000003 xref: CARO:0000003 xref: EHDAA2:0003003 xref: EMAPA:0 -xref: FBbt:00007001 +xref: FBbt:00007001 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:305751 xref: FMA:67135 xref: GAID:781 @@ -7525,7 +7529,7 @@ def: "The surface (external) layer of ectoderm which begins to proliferate short subset: pheno_slim synonym: "surface (external) ectoderm" EXACT [] synonym: "surface ectoderm" EXACT [MP:0012532] -xref: BTO:0006242 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: BTO:0006242 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: EHDAA2:0001968 xref: EHDAA:1494 xref: EHDAA:350 @@ -7638,13 +7642,13 @@ synonym: "fertilized egg stage" RELATED [] synonym: "one cell stage" EXACT [] synonym: "one-cell stage" RELATED [VHOG:0000745] synonym: "zygote" RELATED [VHOG:0000745] -synonym: "zygotum" RELATED LATIN [Wikipedia:Zygote] +synonym: "zygotum" RELATED OMO:0003011 [Wikipedia:Zygote] xref: BilaDO:0000005 xref: BILS:0000106 xref: EFO:0001322 xref: EHDAA:27 xref: FBdv:00005288 -xref: IDOMAL:0000302 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: IDOMAL:0000302 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: NCIT:C12601 xref: PdumDv:0000100 xref: VHOG:0000745 @@ -7791,7 +7795,7 @@ synonym: "funiculus" EXACT [] synonym: "nerve fiber bundle" EXACT [FBbt:00005099] synonym: "neural fiber bundle" EXACT [] xref: CARO:0001001 -xref: FBbt:00005099 +xref: FBbt:00005099 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: NLX:147821 is_a: UBERON:0005162 ! multi cell part structure relationship: has_part GO:0043005 ! neuron projection @@ -7824,13 +7828,13 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "adult mouth" NARROW [] -synonym: "cavital oralis" RELATED LATIN [Wikipedia:Mouth] +synonym: "cavital oralis" RELATED OMO:0003011 [Wikipedia:Mouth] synonym: "cavitas oris" RELATED [BTO:0001090] synonym: "cavum oris" RELATED [BTO:0001090] synonym: "mouth cavity" RELATED [BTO:0001090] synonym: "oral region" RELATED [EHDAA2:0001326] synonym: "oral vestibule" RELATED [BTO:0001090] -synonym: "regio oralis" EXACT LATIN [BTO:0004698, FMA:49184, FMA:TA] +synonym: "regio oralis" EXACT OMO:0003011 [BTO:0004698, FMA:49184, FMA:TA] synonym: "rima oris" RELATED [BTO:0001090] synonym: "stoma" RELATED [] synonym: "stomatodaeum" RELATED [VHOG:0000812] @@ -7845,7 +7849,7 @@ xref: EFO:0000825 xref: EHDAA2:0001326 xref: EHDAA:542 xref: EMAPA:16262 -xref: FBbt:00003126 +xref: FBbt:00003126 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:49184 xref: GAID:75 xref: galen:Mouth @@ -8028,7 +8032,7 @@ xref: CALOHA:TS-2101 xref: CARO:0000004 xref: EHDAA2:0003004 xref: EMAPA:35178 -xref: FBbt:00007019 +xref: FBbt:00007019 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:9669 xref: galen:BodySubstance xref: HAO:0000004 @@ -8063,7 +8067,7 @@ xref: AEO:0000005 xref: BILA:0000005 xref: CARO:0000005 xref: EHDAA2:0003005 -xref: FBbt:00007017 +xref: FBbt:00007017 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:5897 xref: HAO:0000005 xref: NCIT:C94478 @@ -8091,7 +8095,7 @@ xref: AEO:0000006 xref: BILA:0000006 xref: CARO:0000006 xref: EHDAA2:0003006 -xref: FBbt:00007016 +xref: FBbt:00007016 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:67165 xref: HAO:0000006 xref: TAO:0001836 @@ -8117,7 +8121,7 @@ xref: AEO:0000007 xref: BILA:0000007 xref: CARO:0000007 xref: EHDAA2:0003007 -xref: FBbt:00007015 +xref: FBbt:00007015 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:67112 xref: HAO:0000007 xref: TAO:0001835 @@ -8155,11 +8159,11 @@ xref: EHDAA2:0003011 xref: EHDAA:392 xref: EMAPA:16103 xref: EV:0100000 -xref: FBbt:00004856 +xref: FBbt:00004856 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:7149 xref: galen:AnatomicalSystem xref: HAO:0000011 -xref: IDOMAL:0002460 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: IDOMAL:0002460 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: MA:0000003 xref: NCIT:C12919 xref: SCTID:278195005 @@ -8210,7 +8214,7 @@ xref: EHDAA2:0003191 xref: EHDAA:1 xref: EMAPA:25765 xref: EV:0100016 -xref: FBbt:00000001 +xref: FBbt:00000001 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:256135 xref: galen:Organism xref: HAO:0000012 @@ -8255,7 +8259,7 @@ xref: CARO:0000032 xref: EFO:0000808 xref: EHDAA2:0003032 xref: EMAPA:36031 -xref: FBbt:00007009 +xref: FBbt:00007009 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:7153 xref: galen:BodyPart xref: HAO:0000032 @@ -8291,7 +8295,7 @@ xref: AEO:0000040 xref: BILA:0000040 xref: CARO:0000040 xref: EHDAA2:0003040 -xref: FBbt:00007013 +xref: FBbt:00007013 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:63863 xref: HAO:0000040 xref: TAO:0000382 @@ -8311,8 +8315,7 @@ namespace: uberon def: "Anatomical group whose component anatomical structures lie in close proximity to each other." [FBbt:00007277] subset: common_anatomy subset: upper_level -xref: FBbt:00007277 -xref: IDOMAL:0002461 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: FBbt:00007277 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: VHOG:0001737 is_a: UBERON:0034923 ! disconnected anatomical group relationship: present_in_taxon NCBITaxon:33090 @@ -8339,7 +8342,7 @@ xref: CALOHA:TS-2090 xref: CARO:0000043 xref: EHDAA2:0003043 xref: EMAPA:35868 -xref: FBbt:00007003 +xref: FBbt:00007003 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:9637 xref: galen:Tissue xref: HAO:0000043 @@ -8374,7 +8377,7 @@ xref: AEO:0000055 xref: BILA:0000055 xref: CARO:0000055 xref: EHDAA2:0003055 -xref: FBbt:00007010 +xref: FBbt:00007010 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: HAO:0000055 xref: TAO:0001488 xref: TGMA:0001847 @@ -8407,7 +8410,7 @@ xref: CALOHA:TS-0288 xref: CARO:0000066 xref: EHDAA2:0003066 xref: EMAPA:32738 -xref: FBbt:00007005 +xref: FBbt:00007005 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:9639 xref: GAID:402 xref: HAO:0000066 @@ -8584,11 +8587,11 @@ xref: EHDAA2:0000002 xref: EHDAA2_RETIRED:0003236 xref: EHDAA:38 xref: EMAPA:16039 -xref: FBbt:00000052 +xref: FBbt:00000052 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:69068 xref: GAID:963 xref: http://neurolex.org/wiki/Category\:Embryonic_organism -xref: IDOMAL:0000646 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: IDOMAL:0000646 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: MAT:0000226 xref: MESH:D004622 xref: MIAA:0000019 @@ -8628,7 +8631,7 @@ xref: AAO:0000480 xref: BILA:0000035 xref: BTO:0000556 xref: EMAPA:36033 -xref: FBbt:00000110 +xref: FBbt:00000110 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:69069 xref: GAID:1303 xref: MESH:D005855 @@ -8663,7 +8666,7 @@ xref: EFO:0000414 xref: EHDAA2:0000428 xref: EMAPA:16069 xref: EV:0100003 -xref: FBbt:00000111 +xref: FBbt:00000111 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:69070 xref: GAID:1304 xref: MAT:0000155 @@ -8704,7 +8707,7 @@ xref: EFO:0002545 xref: EHDAA2:0000436 xref: EMAPA:16062 xref: EV:0100005 -xref: FBbt:00000125 +xref: FBbt:00000125 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:69071 xref: GAID:1305 xref: MAT:0000175 @@ -8750,7 +8753,7 @@ xref: EHDAA:160 xref: EHDAA:183 xref: EMAPA:16083 xref: EV:0100006 -xref: FBbt:00000126 +xref: FBbt:00000126 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:69072 xref: GAID:522 xref: MAT:0000174 @@ -8794,7 +8797,7 @@ synonym: "stomodeal-hypophyseal primordium" BROAD [XAO:0000269] xref: BTO:0004224 xref: EHDAA2:0001929 xref: EMAPA:16263 -xref: FBbt:00000439 +xref: FBbt:00000439 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:295846 xref: NCIT:C34306 xref: TAO:0001290 @@ -8828,8 +8831,8 @@ synonym: "2n" BROAD OMO:0003000 [BIRNLEX:1640, NIFSTD:NeuroNames_abbrevSource] synonym: "CN-II" RELATED [ZFA:0000435] synonym: "cranial II" EXACT [] synonym: "nerve II" RELATED [NeuroNames:289] -synonym: "nervus opticus" EXACT LATIN [] -synonym: "nervus opticus [II]" EXACT LATIN [FMA:50863, FMA:TA] +synonym: "nervus opticus" EXACT OMO:0003011 [] +synonym: "nervus opticus [II]" EXACT OMO:0003011 [FMA:50863, FMA:TA] synonym: "optic" RELATED [TAO:0000435] synonym: "optic II" EXACT [EHDAA2:0001313] synonym: "optic II nerve" EXACT [EHDAA2:0001313] @@ -8975,7 +8978,7 @@ xref: EHDAA:2641 xref: EHDAA:6485 xref: EMAPA:16894 xref: EV:0100164 -xref: FBbt:00005095 +xref: FBbt:00005095 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:50801 xref: GAID:571 xref: galen:Brain @@ -9040,9 +9043,9 @@ def: "A decussation of the diencephalon where the fibers of the optic nerve cros subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "chiasma" RELATED LATIN [NeuroNames:459] -synonym: "chiasma nervorum opticorum" RELATED LATIN [NeuroNames:459] -synonym: "chiasma opticum" EXACT LATIN [Wikipedia:Optic_chiasm] +synonym: "chiasma" RELATED OMO:0003011 [NeuroNames:459] +synonym: "chiasma nervorum opticorum" RELATED OMO:0003011 [NeuroNames:459] +synonym: "chiasma opticum" EXACT OMO:0003011 [Wikipedia:Optic_chiasm] synonym: "decussation of optic nerve fibers" EXACT [FMA:62045] synonym: "optic chiasm" EXACT [Wikipedia:Optic_chiasm] synonym: "optic chiasm (Rufus of Ephesus)" RELATED [NeuroNames:459] @@ -9260,7 +9263,7 @@ xref: BTO:0000439 xref: CALOHA:TS-0309 xref: EFO:0000827 xref: EV:0100336 -xref: FBbt:00005162 +xref: FBbt:00005162 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: GAID:69 xref: MAT:0000140 xref: MESH:D005123 @@ -9339,7 +9342,7 @@ xref: BTO:0000058 xref: CALOHA:TS-1293 xref: EFO:0000793 xref: EV:0100056 -xref: FBbt:00005055 +xref: FBbt:00005055 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:7152 xref: GAID:278 xref: galen:DigestiveSystem @@ -9378,9 +9381,10 @@ namespace: uberon def: "Organ system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis[WP]." [Wikipedia:Circulatory_system] subset: human_reference_atlas subset: uberon_slim -synonym: "systema cardiovasculare" RELATED LATIN [Wikipedia:Circulatory_system] +synonym: "systema cardiovasculare" RELATED OMO:0003011 [Wikipedia:Circulatory_system] xref: AAO:0000959 xref: CALOHA:TS-2103 +xref: MESH:D002319 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} xref: VHOG:0001248 xref: Wikipedia:Circulatory_system is_a: UBERON:0000467 ! anatomical system @@ -9417,7 +9421,7 @@ synonym: "muscles" RELATED [] synonym: "muscles set" EXACT [] synonym: "musculature" EXACT [] synonym: "musculature system" RELATED [] -synonym: "musculi" EXACT LATIN [FMA:32558, FMA:TA] +synonym: "musculi" EXACT OMO:0003011 [FMA:32558, FMA:TA] synonym: "set of muscles" EXACT [FMA:32558] synonym: "set of skeletal muscles" EXACT [MA:0000165] xref: AAO:0011066 @@ -9448,12 +9452,13 @@ namespace: uberon def: "The nervous system is an organ system containing predominantly neuron and glial cells. In bilaterally symmetrical organism, it is arranged in a network of tree-like structures connected to a central body. The main functions of the nervous system are to regulate and control body functions, and to receive sensory input, process this information, and generate behavior [CUMBO]." [BIRNLEX:844, ISBN:0-14-051288-8, ISBN:3110148986, NLM:nervous+system, WB:rynl, Wikipedia:Nervous_system, ZFIN:curator] subset: cumbo subset: efo_slim +subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "nerve net" NARROW [Wikipedia:Nerve_net] synonym: "neurological system" EXACT [GO:0050877] -synonym: "systema nervosum" RELATED LATIN [Wikipedia:Nervous_system] +synonym: "systema nervosum" RELATED OMO:0003011 [Wikipedia:Nervous_system] xref: AAO:0000324 xref: BILA:0000079 xref: BIRNLEX:844 @@ -9464,7 +9469,7 @@ xref: EHDAA2:0001246 xref: EHDAA:826 xref: EMAPA:16469 xref: EV:0100162 -xref: FBbt:00005093 +xref: FBbt:00005093 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:7157 xref: GAID:466 xref: MA:0000016 @@ -9493,6 +9498,7 @@ relationship: has_part CL:0000540 ! neuron relationship: immediate_transformation_of UBERON:0016880 {source="Bgee:AN"} ! future nervous system relationship: never_in_taxon NCBITaxon:6040 relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa +relationship: present_in_taxon NCBITaxon:9606 property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/b/b2/TE-Nervous_system_diagram.svg" xsd:anyURI property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/b/ba/Nervous_system_diagram.png" xsd:anyURI property_value: UBPROP:0000001 "A regulatory system of the body that consists of neurons and neuroglial cells. The nervous system is divided into two parts, the central nervous system (CNS) and the peripheral nervous system (PNS). (Source: BioGlossary, www.Biology-Text.com)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000396", ontology="TAO", source="ZFIN:curator"} @@ -9508,13 +9514,14 @@ namespace: uberon def: "The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the neural tube derivatives: the brain and spinal cord. In invertebrates it includes central ganglia plus nerve cord." [GO:0021551, http://www.frontiersinzoology.com/content/7/1/29, https://sourceforge.net/p/geneontology/ontology-requests/11422/] subset: cumbo subset: efo_slim +subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "cerebrospinal axis" NARROW [FMA:55675] synonym: "CNS" EXACT OMO:0003000 [] synonym: "neuraxis" RELATED [FMA:55675] -synonym: "systema nervosum centrale" EXACT LATIN [FMA:55675, FMA:TA] +synonym: "systema nervosum centrale" EXACT OMO:0003011 [FMA:55675, FMA:TA] xref: AAO:0000090 xref: BAMS:CNS xref: BILA:0000080 @@ -9527,7 +9534,7 @@ xref: EHDAA:828 xref: EMAPA:16470 xref: EMAPA:16754 xref: EV:0100163 -xref: FBbt:00005094 +xref: FBbt:00005094 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:55675 xref: GAID:570 xref: MA:0000167 @@ -9548,6 +9555,7 @@ relationship: immediate_transformation_of UBERON:0016879 {source="Bgee:AN"} ! fu relationship: never_in_taxon NCBITaxon:147099 {source="Wikipedia:Acoelomorpha"} relationship: only_in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of UBERON:0001016 ! nervous system +relationship: present_in_taxon NCBITaxon:9606 property_value: UBPROP:0000001 "Part of the nervous system which includes the brain and spinal cord.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000090", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000001 "The brain and spinal cord. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000012", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "The central nervous system (CNS) is the part of the nervous system which includes the brain, spinal cord, and nerve cell layer of the retina (CUMBO)." xsd:string {source="BIRNLEX:1099"} @@ -9569,7 +9577,7 @@ synonym: "tract" RELATED [] synonym: "tract of neuraxis" EXACT [FMA:83847] xref: BIRNLEX:1649 xref: EV:0100304 -xref: FBbt:00005100 +xref: FBbt:00005100 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:83847 xref: NLX:147822 is_a: UBERON:0000122 ! neuron projection bundle @@ -9584,7 +9592,7 @@ def: "A slender neuron projection bundle[FBbt]; A bundle of anatomical fibers, a comment: EDITOR_NOTE note FBbt class not disjoint from tract. Consider merging with 'neuron projection bundle' subset: uberon_slim synonym: "fascicle" BROAD [FBbt:00005101] -synonym: "fasciculus" EXACT LATIN [] +synonym: "fasciculus" EXACT OMO:0003011 [] synonym: "nerve bundle" EXACT [FMA:12235] synonym: "nerve fasciculus" EXACT [FMA:12235] synonym: "nerve fiber tract" RELATED [BTO:0002191] @@ -9607,8 +9615,8 @@ def: "Anatomical system that overlaps the nervous system and is responsible for subset: efo_slim subset: uberon_slim subset: vertebrate_core -synonym: "organa sensuum" EXACT LATIN [FMA:75259, FMA:TA] -synonym: "organa sensuum" RELATED LATIN [Wikipedia:Sensory_system] +synonym: "organa sensuum" EXACT OMO:0003011 [FMA:75259, FMA:TA] +synonym: "organa sensuum" RELATED OMO:0003011 [Wikipedia:Sensory_system] synonym: "sense organ subsystem" EXACT [] synonym: "sense organs" EXACT [FMA:75259] synonym: "sense organs set" EXACT [FMA:75259] @@ -9622,7 +9630,7 @@ xref: BILA:0000099 xref: EFO:0000805 xref: EHDAA2:0003094 xref: EMAPA:16192 -xref: FBbt:00007692 +xref: FBbt:00007692 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:75259 xref: MA:0002442 xref: MAT:0000031 @@ -9658,7 +9666,7 @@ xref: AEO:0000171 xref: BTO:0001886 xref: EFO:0001652 xref: EHDAA2:0003171 -xref: FBbt:00005495 +xref: FBbt:00005495 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:86589 xref: MAT:0000482 xref: NCIT:C34275 @@ -9678,7 +9686,7 @@ subset: uberon_slim subset: vertebrate_core synonym: "neural primordium" RELATED [] synonym: "presumptive central nervous system" RELATED [] -synonym: "tubus neuralis" RELATED LATIN [Wikipedia:Neural_tube] +synonym: "tubus neuralis" RELATED OMO:0003011 [Wikipedia:Neural_tube] xref: AAO:0010617 xref: BTO:0001057 xref: CALOHA:TS-2371 @@ -9690,7 +9698,7 @@ xref: EMAPA:16164 xref: EMAPA:16757 xref: FMA:293882 xref: MAT:0000069 -xref: MESH:D054259 +xref: MESH:D054259 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: MIAA:0000069 xref: NCIT:C34226 xref: neuronames:1365 @@ -9726,7 +9734,7 @@ xref: BILA:0000000 xref: BIRNLEX:6 xref: CARO:0000000 xref: EHDAA2:0002229 -xref: FBbt:10000000 +xref: FBbt:10000000 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:62955 xref: HAO:0000000 xref: MA:0000001 @@ -9753,8 +9761,8 @@ subset: vertebrate_core synonym: "involuntary muscle" EXACT [] synonym: "non-striated muscle" EXACT [] synonym: "smooth muscle" EXACT [] -synonym: "textus muscularis levis; textus muscularis nonstriatus" RELATED LATIN [Wikipedia:Smooth_muscle_tissue] -synonym: "textus muscularis nonstriatus" EXACT LATIN [FMA:14070, FMA:TA] +synonym: "textus muscularis levis; textus muscularis nonstriatus" RELATED OMO:0003011 [Wikipedia:Smooth_muscle_tissue] +synonym: "textus muscularis nonstriatus" EXACT OMO:0003011 [FMA:14070, FMA:TA] synonym: "visceral muscle" NARROW SENSU [] synonym: "visceral muscle tissue" NARROW SENSU [] xref: AAO:0010244 @@ -9920,7 +9928,7 @@ namespace: uberon def: "A subdivision of the head that has as parts the layers deep to the surface of the anterior surface, including the mouth, eyes, and nose (when present). In vertebrates, this includes the facial skeleton and structures superficial to the facial skeleton (cheeks, mouth, eyeballs, skin of face, etc)." [http://orcid.org/0000-0002-6601-2165] subset: pheno_slim subset: uberon_slim -synonym: "facia/facies" RELATED LATIN [Wikipedia:Face] +synonym: "facia/facies" RELATED OMO:0003011 [Wikipedia:Face] synonym: "visage" RELATED [BTO:0003369] xref: BTO:0003369 xref: CALOHA:TS-2216 @@ -9966,10 +9974,11 @@ xref: BTO:0000545 xref: EHDAA2:0000726 xref: EHDAA:518 xref: EMAPA:16247 -xref: FBbt:00003125 +xref: FBbt:00003125 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:45615 xref: galen:AlimentaryTract xref: MA:0000917 +xref: MESH:D041981 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} xref: NCIT:C34082 xref: TAO:0000112 xref: TGMA:0001819 @@ -10001,7 +10010,7 @@ subset: pheno_slim subset: uberon_slim synonym: "Bowman`s muscles" RELATED [BTO:0000654] synonym: "ciliaris" RELATED [Wikipedia:Ciliary_muscle] -synonym: "musculus ciliaris" RELATED LATIN [Wikipedia:Ciliary_muscle] +synonym: "musculus ciliaris" RELATED OMO:0003011 [Wikipedia:Ciliary_muscle] synonym: "musculus ciliarus" EXACT [BTO:0000654] xref: BTO:0000654 xref: EMAPA:35240 @@ -10100,7 +10109,7 @@ synonym: "anterior chamber" EXACT [HP:0000593, MP:0010709] synonym: "anterior chamber of eye" EXACT [] synonym: "camera anterior" EXACT [] synonym: "camera anterior bulbi" RELATED [BTO:0002084] -synonym: "camera anterior bulbi oculi" RELATED LATIN [Wikipedia:Anterior_chamber_of_eyeball] +synonym: "camera anterior bulbi oculi" RELATED OMO:0003011 [Wikipedia:Anterior_chamber_of_eyeball] synonym: "camera oculi anterior" RELATED [BTO:0002084] synonym: "eye anterior chamber" EXACT [] xref: BTO:0002084 @@ -10132,7 +10141,7 @@ subset: pheno_slim subset: uberon_slim synonym: "pars iridica retinae" RELATED [Wikipedia:Uvea] synonym: "tunica vasculatis oculi" RELATED [Wikipedia:Uvea] -synonym: "tunica vasculosa bulbi" RELATED LATIN [Wikipedia:Uvea] +synonym: "tunica vasculosa bulbi" RELATED OMO:0003011 [Wikipedia:Uvea] synonym: "tunica vasculosa of eyeball" EXACT [FMA:58103] synonym: "uvea" EXACT [FMA:58103] synonym: "uveal tract" EXACT [FMA:58103] @@ -10214,13 +10223,13 @@ synonym: "anterior corneal epithelium" EXACT [] synonym: "anterior endothelium of cornea" RELATED [BTO:0000287] synonym: "cornea epithelial tissue" EXACT [OBOL:automatic] synonym: "cornea epithelium" EXACT [OBOL:automatic] -synonym: "e. anterius corneae" RELATED LATIN [Wikipedia:Corneal_epithelium] +synonym: "e. anterius corneae" RELATED OMO:0003011 [Wikipedia:Corneal_epithelium] synonym: "endothelium anterius corneae" RELATED [BTO:0000287] synonym: "endothelium camerae anterioris bulbi" RELATED [BTO:0000287] synonym: "endothelium corneale" RELATED [BTO:0000287] synonym: "epithelial tissue of cornea" EXACT [OBOL:automatic] synonym: "epithelium anterius (cornea)" EXACT [] -synonym: "epithelium anterius corneae" EXACT LATIN [FMA:58263, FMA:TA] +synonym: "epithelium anterius corneae" EXACT OMO:0003011 [FMA:58263, FMA:TA] synonym: "epithelium corneæ anterior layer" EXACT [] synonym: "epithelium of cornea" EXACT [] synonym: "epithelium posterius corneae" RELATED [BTO:0000287] @@ -10306,7 +10315,7 @@ subset: uberon_slim subset: vertebrate_core synonym: "anterior uvea" RELATED [] synonym: "ciliary bodies" RELATED OMO:0003004 [VHOG:0000102] -synonym: "corpus ciliare" RELATED LATIN [Wikipedia:Ciliary_body] +synonym: "corpus ciliare" RELATED OMO:0003011 [Wikipedia:Ciliary_body] synonym: "ocular ciliary body" EXACT [] xref: AAO:0010341 xref: BTO:0000260 @@ -10348,7 +10357,7 @@ synonym: "chorioid" RELATED [BTO:0001829] synonym: "choroid" EXACT [MA:0000263] synonym: "choroid coat" EXACT [Wikipedia:Choroid] synonym: "choroidea" EXACT [Wikipedia:Choroid] -synonym: "choroidea" RELATED LATIN [Wikipedia:Choroid] +synonym: "choroidea" RELATED OMO:0003011 [Wikipedia:Choroid] synonym: "eye choroid" EXACT [VHOG:0001568] synonym: "optic choroid" RELATED [ZFA:0005229] synonym: "posterior uvea" EXACT [Wikipedia:Uvea#Regions] @@ -10394,7 +10403,7 @@ subset: vertebrate_core synonym: "corneal stroma" EXACT [MA:0001245] synonym: "stroma of cornea" EXACT [] synonym: "substantia propria" BROAD [] -synonym: "substantia propria corneae" EXACT LATIN [FMA:58306, FMA:TA] +synonym: "substantia propria corneae" EXACT OMO:0003011 [FMA:58306, FMA:TA] xref: CALOHA:TS-1138 xref: EFO:0002514 xref: EMAPA:17602 @@ -10483,7 +10492,7 @@ subset: uberon_slim subset: vertebrate_core synonym: "epithelium, retinal pigment" RELATED [BTO:0001177] synonym: "outer pigmented layer of retina" EXACT [] -synonym: "p. pigmentosa retinae" RELATED LATIN [Wikipedia:Retinal_pigment_epithelium] +synonym: "p. pigmentosa retinae" RELATED OMO:0003011 [Wikipedia:Retinal_pigment_epithelium] synonym: "pigment epithelium of retina" EXACT [] synonym: "pigmented epithelium" RELATED [] synonym: "pigmented retina" RELATED [] @@ -10494,9 +10503,9 @@ synonym: "retinal pigment epithelium" EXACT [MP:0005201, Wikipedia:Retinal_pigme synonym: "retinal pigment layer" RELATED [VHOG:0000536] synonym: "retinal pigmented epithelium" EXACT [ZFA:0000144] synonym: "RPE" RELATED [] -synonym: "stratum pigmentosa retinae" RELATED LATIN [Wikipedia:Retinal_pigment_epithelium] +synonym: "stratum pigmentosa retinae" RELATED OMO:0003011 [Wikipedia:Retinal_pigment_epithelium] synonym: "stratum pigmentosum (retina)" EXACT [] -synonym: "stratum pigmentosum retinae" EXACT LATIN [FMA:58627, FMA:TA] +synonym: "stratum pigmentosum retinae" EXACT OMO:0003011 [FMA:58627, FMA:TA] xref: AAO:0011096 xref: BTO:0001177 xref: CALOHA:TS-0869 @@ -10544,7 +10553,7 @@ synonym: "retina photoreceptor layer" EXACT [] synonym: "retinal photoreceptor layer" EXACT [ZFA:0000143] synonym: "retinal photoreceptor layers" RELATED OMO:0003004 [ZFA:0000143] synonym: "stratum segmentorum externorum et internorum (retina)" EXACT [] -synonym: "stratum segmentorum externorum et internorum retinae" EXACT LATIN [FMA:58680, FMA:TA] +synonym: "stratum segmentorum externorum et internorum retinae" EXACT OMO:0003011 [FMA:58680, FMA:TA] xref: EMAPA:35686 xref: FMA:58680 xref: MA:0001308 @@ -10581,7 +10590,7 @@ synonym: "outer limiting membranes" RELATED OMO:0003004 [ZFA:0001331] synonym: "retina external limiting lamina" EXACT [] synonym: "retina outer limiting membrane" EXACT [MP:0010236] synonym: "stratum limitans externum (retina)" EXACT [] -synonym: "stratum limitans externum retinae" EXACT LATIN [FMA:58683, FMA:TA] +synonym: "stratum limitans externum retinae" EXACT OMO:0003011 [FMA:58683, FMA:TA] xref: EMAPA:36518 xref: FMA:58683 xref: MA:0001309 @@ -10613,7 +10622,7 @@ synonym: "retina, outer nuclear layer" RELATED [BAMS:Ronl] synonym: "retinal outer nuclear layer" EXACT [] synonym: "retinal outer nuclear layers" RELATED OMO:0003004 [ZFA:0001464] synonym: "stratum nucleare externum (retina)" EXACT [] -synonym: "stratum nucleare externum retinae" EXACT LATIN [FMA:58684, FMA:TA] +synonym: "stratum nucleare externum retinae" EXACT OMO:0003011 [FMA:58684, FMA:TA] xref: BAMS:Ronl xref: BTO:0005600 xref: EMAPA:19157 @@ -10650,7 +10659,7 @@ synonym: "retina, outer plexiform layer" RELATED [BAMS:Ropl] synonym: "retinal outer plexiform layer" EXACT [] synonym: "retinal outer plexiform layers" RELATED OMO:0003004 [ZFA:0001330] synonym: "stratum plexiforme externum" EXACT [] -synonym: "stratum plexiforme externum retinae" EXACT LATIN [FMA:58685, FMA:TA] +synonym: "stratum plexiforme externum retinae" EXACT OMO:0003011 [FMA:58685, FMA:TA] xref: BAMS:Ropl xref: BTO:0003174 xref: EMAPA:35744 @@ -10689,7 +10698,7 @@ synonym: "retina inner nuclear layer" EXACT [] synonym: "retina, inner nuclear layer" RELATED [BAMS:Rinl] synonym: "retinal inner nuclear layer" EXACT [] synonym: "stratum nucleare internum" EXACT [] -synonym: "stratum nucleare internum retinae" EXACT LATIN [FMA:58686, FMA:TA] +synonym: "stratum nucleare internum retinae" EXACT OMO:0003011 [FMA:58686, FMA:TA] xref: BAMS:Rinl xref: BTO:0003176 xref: EMAPA:19155 @@ -10735,7 +10744,7 @@ synonym: "retinal ganglion cell layer" EXACT [] synonym: "retinal ganglion layer" EXACT [MP:0008510] synonym: "RGC layer" EXACT [] synonym: "stratum ganglionicum (retina)" EXACT [FMA:58687] -synonym: "stratum ganglionicum retinae" RELATED LATIN [Wikipedia:Ganglion_cell_layer] +synonym: "stratum ganglionicum retinae" RELATED OMO:0003011 [Wikipedia:Ganglion_cell_layer] xref: BAMS:Rgcl xref: BTO:0003398 xref: CALOHA:TS-0867 @@ -10779,8 +10788,8 @@ synonym: "optic fiber layer" RELATED [VHOG:0001169] synonym: "optic fiber layers" RELATED OMO:0003004 [TAO:0002212] synonym: "retina nerve fiber layer" EXACT [] synonym: "stratum neurofibrarum (retina)" EXACT [] -synonym: "stratum neurofibrarum retinae" EXACT LATIN [FMA:58688, FMA:TA] -synonym: "stratum neurofibrum retinae" RELATED LATIN [Wikipedia:Nerve_fiber_layer] +synonym: "stratum neurofibrarum retinae" EXACT OMO:0003011 [FMA:58688, FMA:TA] +synonym: "stratum neurofibrum retinae" RELATED OMO:0003011 [Wikipedia:Nerve_fiber_layer] synonym: "stratum opticum of retina" EXACT [] xref: DMBA:15652 xref: EMAPA:18591 @@ -10815,7 +10824,7 @@ synonym: "internal limiting lamina of retina" EXACT [] synonym: "internal limiting membrane of retina" EXACT [] synonym: "retina inner limiting membrane" EXACT [MP:0010235] synonym: "retina internal limiting lamina" EXACT [] -synonym: "stratum limitans internum retinae" EXACT LATIN [FMA:58689, FMA:TA] +synonym: "stratum limitans internum retinae" EXACT OMO:0003011 [FMA:58689, FMA:TA] xref: EMAPA:36519 xref: FMA:58689 xref: MA:0001313 @@ -10850,7 +10859,7 @@ synonym: "retinal inner plexiform layer" EXACT [] synonym: "retinal internal plexiform layer" RELATED [NLXANAT:1005032] synonym: "stratum plexifome internum" RELATED [BTO:0003175] synonym: "stratum plexiforme internum" EXACT [FMA:58704] -synonym: "stratum plexiforme internum retinae" RELATED LATIN [Wikipedia:Inner_plexiform_layer] +synonym: "stratum plexiforme internum retinae" RELATED OMO:0003011 [Wikipedia:Inner_plexiform_layer] xref: BAMS:Ripl xref: BTO:0003175 xref: EMAPA:35741 @@ -10893,7 +10902,7 @@ subset: uberon_slim subset: vertebrate_core synonym: "aqueous humor" EXACT [] synonym: "aqueous humour" EXACT [EHDAA2:0000139] -synonym: "humor aquosus" EXACT LATIN [FMA:58819, FMA:TA] +synonym: "humor aquosus" EXACT OMO:0003011 [FMA:58819, FMA:TA] xref: EHDAA2:0000139 xref: EHDAA:10196 xref: EMAPA:18232 @@ -10926,7 +10935,7 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "humor vitreous" EXACT [] -synonym: "humor vitreus" EXACT LATIN [FMA:58822, FMA:TA] +synonym: "humor vitreus" EXACT OMO:0003011 [FMA:58822, FMA:TA] synonym: "humoral fluid" RELATED [BTO:0001451] synonym: "ocular fluid" RELATED [BTO:0001451] synonym: "portion of vitreous humor" BROAD [FMA:67388] @@ -10941,6 +10950,7 @@ xref: ENVO:02000032 xref: EV:0100344 xref: FMA:58822 xref: MA:0001286 +xref: MESH:D014822 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} xref: NCIT:C13323 xref: UMLS:C0229096 {source="ncithesaurus:Vitreous_Humor"} xref: VHOG:0000795 @@ -10982,7 +10992,7 @@ namespace: uberon def: "The chamber in the eyeball enclosing the vitreous humor, bounded anteriorly by the lens and ciliary body and posteriorly by the posterior wall of the eyeball[BTO,modified]." [BTO:0002087] subset: uberon_slim synonym: "camera postrema" EXACT [FMA:58848] -synonym: "camera postrema bulbi oculi" EXACT LATIN [FMA:58848, FMA:TA] +synonym: "camera postrema bulbi oculi" EXACT OMO:0003011 [FMA:58848, FMA:TA] synonym: "camera vitrea" EXACT [FMA:58848] synonym: "camera vitrea bulbi" EXACT [FMA:58848] synonym: "postremal chamber" EXACT [FMA:58848] @@ -11014,7 +11024,7 @@ synonym: "anterior segment of eye" EXACT [] synonym: "anterior segment of the eye" EXACT [] synonym: "eye anterior segment" EXACT [] synonym: "segmentum anterius (bulbus oculi)" EXACT [] -synonym: "segmentum anterius bulbi oculi" RELATED LATIN [Wikipedia:Anterior_segment_of_eyeball] +synonym: "segmentum anterius bulbi oculi" RELATED OMO:0003011 [Wikipedia:Anterior_segment_of_eyeball] xref: EMAPA:36594 xref: FMA:58865 xref: MA:0002484 @@ -11045,7 +11055,7 @@ synonym: "posterior segment eye" EXACT [ZFA:0005567] synonym: "posterior segment of eye" EXACT [] synonym: "posterior segment of the eye" EXACT [] synonym: "segmentum posterius (bulbus oculi)" EXACT [] -synonym: "segmentum posterius bulbi oculi" RELATED LATIN [Wikipedia:Posterior_segment_of_eyeball] +synonym: "segmentum posterius bulbi oculi" RELATED OMO:0003011 [Wikipedia:Posterior_segment_of_eyeball] xref: EMAPA:36595 xref: FMA:58868 xref: MA:0002485 @@ -11071,7 +11081,7 @@ subset: pheno_slim subset: uberon_slim synonym: "conjunctivae" EXACT OMO:0003004 [XAO:0000182] synonym: "conjunctivas" EXACT OMO:0003004 [XAO:0000182] -synonym: "tunica conjunctiva" EXACT LATIN [FMA:TA] +synonym: "tunica conjunctiva" EXACT OMO:0003011 [FMA:TA] synonym: "wall of conjunctival sac" EXACT [FMA:59011] xref: AAO:0010343 xref: BTO:0003415 @@ -11162,7 +11172,7 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "MB" BROAD OMO:0003000 [BIRNLEX:1667, NIFSTD:NeuroNames_abbrevSource] -synonym: "mesencephalon" RELATED LATIN [Wikipedia:Midbrain] +synonym: "mesencephalon" RELATED OMO:0003011 [Wikipedia:Midbrain] xref: AAO:0010149 xref: BAMS:MES xref: BIRNLEX:1667 @@ -11222,7 +11232,7 @@ subset: vertebrate_core synonym: "between brain" EXACT [] synonym: "betweenbrain" RELATED [BTO:0000342] synonym: "DiE" BROAD OMO:0003000 [BIRNLEX:1503, NIFSTD:NeuroNames_abbrevSource] -synonym: "diencephalon" RELATED LATIN [Wikipedia:Diencephalon] +synonym: "diencephalon" RELATED OMO:0003011 [Wikipedia:Diencephalon] synonym: "interbrain" EXACT [Swanson:2004] synonym: "mature diencephalon" EXACT [FMA:62001] synonym: "thalamencephalon" EXACT [MGI:anna] @@ -11291,9 +11301,9 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "bulb" BROAD [] -synonym: "bulbus" EXACT LATIN [FMA:62004, FMA:TA] +synonym: "bulbus" EXACT OMO:0003011 [FMA:62004, FMA:TA] synonym: "medulla" BROAD [ABA:MY] -synonym: "medulla oblonzata" RELATED LATIN [Wikipedia:Medulla_oblongata] +synonym: "medulla oblonzata" RELATED OMO:0003011 [Wikipedia:Medulla_oblongata] synonym: "metepencephalon" RELATED [FMA:62004] xref: AAO:0010486 xref: BAMS:Md @@ -11349,8 +11359,8 @@ subset: uberon_slim subset: vertebrate_core synonym: "optic lemniscus" EXACT [] synonym: "optic tracts" RELATED OMO:0003004 [ZFA:0000252] -synonym: "tractus optici" RELATED LATIN [NeuroNames:460] -synonym: "tractus opticus" RELATED LATIN [Wikipedia:Optic_tract] +synonym: "tractus optici" RELATED OMO:0003011 [NeuroNames:460] +synonym: "tractus opticus" RELATED OMO:0003011 [Wikipedia:Optic_tract] synonym: "visual pathway" RELATED [GAID:735] xref: BAMS:opt xref: BIRNLEX:1684 @@ -11401,8 +11411,8 @@ subset: vertebrate_core synonym: "mesencephalic tegmentum" RELATED [VHOG:0001367] synonym: "MTg" BROAD OMO:0003000 [BIRNLEX:1200, NIFSTD:NeuroNames_abbrevSource] synonym: "tegmentum" BROAD [ISBN:0471888893] -synonym: "tegmentum mesencephali" EXACT LATIN [Wikipedia:Midbrain_tegmentum] -synonym: "tegmentum mesencephalicum" RELATED LATIN [NeuroNames:491] +synonym: "tegmentum mesencephali" EXACT OMO:0003011 [Wikipedia:Midbrain_tegmentum] +synonym: "tegmentum mesencephalicum" RELATED OMO:0003011 [NeuroNames:491] synonym: "tegmentum of midbrain" EXACT [] xref: BAMS:MTg xref: BIRNLEX:1200 @@ -11415,6 +11425,7 @@ xref: FMA:62393 xref: HBA:9002 xref: MA:0000212 xref: MAT:0000452 +xref: MESH:D013681 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} xref: neuronames:491 {source="BIRNLEX:1200"} xref: SCTID:362392007 xref: TAO:0000160 @@ -11478,7 +11489,7 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "region of vascular tree organ" EXACT [FMA:50722] -synonym: "vas sanguineum" RELATED LATIN [Wikipedia:Blood_vessel] +synonym: "vas sanguineum" RELATED OMO:0003011 [Wikipedia:Blood_vessel] synonym: "vascular element" BROAD [EMAPA:35993] synonym: "vascular tree organ region" EXACT [FMA:50722] xref: AAO:0011004 @@ -11535,7 +11546,7 @@ subset: uberon_slim subset: vertebrate_core synonym: "cornea endothelium" EXACT [OBOL:automatic] synonym: "endothelium of cornea" EXACT [OBOL:automatic] -synonym: "epithelium posterius corneae" RELATED LATIN [Wikipedia:Corneal_endothelium] +synonym: "epithelium posterius corneae" RELATED OMO:0003011 [Wikipedia:Corneal_endothelium] xref: CALOHA:TS-0172 xref: EMAPA:35935 xref: FMA:63882 @@ -11602,9 +11613,9 @@ synonym: "gray matter of neuraxis" EXACT [FMA:67242] synonym: "grey matter" EXACT [] synonym: "grey matter of neuraxis" EXACT [] synonym: "grey substance" EXACT [] -synonym: "grisea" RELATED LATIN [] +synonym: "grisea" RELATED OMO:0003011 [] synonym: "neuronal grey matter" EXACT [AEO:0001012] -synonym: "substantia grisea" EXACT LATIN [FMA:67242, FMA:TA] +synonym: "substantia grisea" EXACT OMO:0003011 [FMA:67242, FMA:TA] xref: AEO:0001012 xref: EHDAA2:0003136 xref: EHDAA2_RETIRED:0004658 @@ -11612,7 +11623,7 @@ xref: EMAPA:37596 {source="MA:th"} xref: FMA:67242 xref: HBA:4006 xref: MA:0001112 -xref: MESH:D066128 +xref: MESH:D066128 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: NCIT:C32695 xref: neuronames:2869 xref: TAO:0002197 @@ -11723,7 +11734,7 @@ xref: BILA:0000034 xref: BTO:0000174 xref: CALOHA:TS-2110 xref: EFO:0000461 -xref: FBbt:00004208 +xref: FBbt:00004208 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:69067 xref: GAID:407 xref: MESH:D004628 @@ -11799,6 +11810,7 @@ xref: EMAPA:37721 {source="MA:th"} xref: FMA:71221 xref: MA:0002986 xref: MAT:0000148 +xref: MESH:D013131 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} xref: MIAA:0000148 xref: TAO:0000317 xref: VHOG:0000317 @@ -11993,7 +12005,7 @@ namespace: uberon def: "The part of the coelemic cavity lumen that is enclosed by the walls of the thorax." [UBERON:cjm, Wikipedia:Thoracic_cavity] subset: pheno_slim subset: uberon_slim -synonym: "cavitas thoracis" EXACT LATIN [Wikipedia:Thoracic_cavity] +synonym: "cavitas thoracis" EXACT OMO:0003011 [Wikipedia:Thoracic_cavity] synonym: "cavity of chest" EXACT [] synonym: "cavity of thorax" EXACT [] synonym: "chest cavity" EXACT [] @@ -12034,9 +12046,9 @@ subset: uberon_slim subset: vertebrate_core synonym: "cerebro-cerebellar fissure" RELATED [NeuroNames:22] synonym: "cerebrocerebellar fissure" RELATED [NeuroNames:22] -synonym: "fissura cerebro-cerebellaris" RELATED LATIN [NeuroNames:22] -synonym: "fissura cerebrocerebellaris" RELATED LATIN [NeuroNames:22] -synonym: "medulla spinalis" RELATED LATIN [BTO:0001279, Wikipedia:Spinal_cord] +synonym: "fissura cerebro-cerebellaris" RELATED OMO:0003011 [NeuroNames:22] +synonym: "fissura cerebrocerebellaris" RELATED OMO:0003011 [NeuroNames:22] +synonym: "medulla spinalis" RELATED OMO:0003011 [BTO:0001279, Wikipedia:Spinal_cord] synonym: "SpC" RELATED OMO:0003000 [] synonym: "spinal cord structure" RELATED [ZFA:0000075] synonym: "spinal medulla" RELATED [BTO:0001279] @@ -12099,12 +12111,12 @@ subset: uberon_slim subset: vertebrate_core synonym: "accessory medullary lamina of pallidum" RELATED [NeuroNames:236] synonym: "brain stem" EXACT [ABA:BS] -synonym: "lamella pallidi incompleta" RELATED LATIN [NeuroNames:236] -synonym: "lamina medullaris accessoria" RELATED LATIN [NeuroNames:236] -synonym: "lamina medullaris incompleta pallidi" RELATED LATIN [NeuroNames:236] -synonym: "lamina pallidi incompleta" RELATED LATIN [NeuroNames:236] -synonym: "truncus encephali" EXACT LATIN [Wikipedia:Brainstem] -synonym: "truncus encephalicus" RELATED LATIN [BTO:0000146] +synonym: "lamella pallidi incompleta" RELATED OMO:0003011 [NeuroNames:236] +synonym: "lamina medullaris accessoria" RELATED OMO:0003011 [NeuroNames:236] +synonym: "lamina medullaris incompleta pallidi" RELATED OMO:0003011 [NeuroNames:236] +synonym: "lamina pallidi incompleta" RELATED OMO:0003011 [NeuroNames:236] +synonym: "truncus encephali" EXACT OMO:0003011 [Wikipedia:Brainstem] +synonym: "truncus encephalicus" RELATED OMO:0003011 [BTO:0000146] xref: BAMS:BS xref: BIRNLEX:1565 xref: BTO:0000146 @@ -12148,7 +12160,7 @@ synonym: "CNS tract/commissure" EXACT [ZFA:0001682] synonym: "CNS tracts and commissures" RELATED [TAO:0000145] synonym: "CNS white matter" RELATED [TAO:0002143] synonym: "neuronal white matter" EXACT [AEO:0001011] -synonym: "substantia alba" RELATED LATIN [Wikipedia:White_matter] +synonym: "substantia alba" RELATED OMO:0003011 [Wikipedia:White_matter] synonym: "white mater" RELATED [VHOG:0001764] synonym: "white matter of neuraxis" EXACT [FMA:83929] synonym: "white substance" EXACT [] @@ -12158,7 +12170,7 @@ xref: EMAPA:35927 xref: FMA:83929 xref: HBA:9218 xref: MA:0001135 -xref: MESH:D066127 +xref: MESH:D066127 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: NCIT:C33892 xref: neuronames:2870 xref: NLX:412 @@ -12202,7 +12214,7 @@ synonym: "ventral body cavity" NARROW [NCBITaxon:7742] xref: AEO:0000186 xref: BTO:0001707 xref: EHDAA2:0000267 -xref: FBbt:00005060 +xref: FBbt:00005060 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:85006 xref: galen:BodyCavity xref: NCIT:C25444 @@ -12228,7 +12240,7 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "embryonic notocord" EXACT [] -synonym: "notochorda" RELATED LATIN [Wikipedia:Notochord] +synonym: "notochorda" RELATED OMO:0003011 [Wikipedia:Notochord] synonym: "notocord" EXACT [ZFA:0000135] xref: AAO:0000327 xref: BTO:0001768 @@ -12287,7 +12299,7 @@ synonym: "epithelial somite" RELATED [https://github.com/obophenotype/uberon/wik synonym: "mesodermal cluster" BROAD [GO:0001756] synonym: "somites" RELATED OMO:0003004 [] synonym: "somitic mesoderm" RELATED [] -synonym: "somitus" RELATED LATIN [Wikipedia:Somite] +synonym: "somitus" RELATED OMO:0003011 [Wikipedia:Somite] xref: AAO:0010569 xref: AEO:0001015 xref: BTO:0001558 @@ -12331,7 +12343,7 @@ comment: Gene notes: Many factors and genes, such as Pax3 (Tremblay et al., 1995 subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "crista neuralis" RELATED LATIN [Wikipedia:Neural_crest] +synonym: "crista neuralis" RELATED OMO:0003011 [Wikipedia:Neural_crest] synonym: "NC" EXACT OMO:0003000 [XAO:0000048] synonym: "neural crest material" RELATED [VHOG:0000057] xref: AAO:0010578 @@ -12377,7 +12389,7 @@ namespace: uberon def: "Embryonic ectoderm that gives rise to nervous tissue." [Wikipedia:Neuroectoderm] subset: uberon_slim subset: vertebrate_core -synonym: "epithelium tubi neuralis; neuroectoderma" RELATED LATIN [Wikipedia:Neuroectoderm] +synonym: "epithelium tubi neuralis; neuroectoderma" RELATED OMO:0003011 [Wikipedia:Neuroectoderm] synonym: "neuaral ectoderm" RELATED [] synonym: "neural ectoderm" EXACT [] synonym: "neuroectoderm" EXACT [] @@ -12391,7 +12403,7 @@ xref: EHDAA:1498 xref: EHDAA:255 xref: EMAPA:16073 xref: EV:0100004 -xref: FBbt:00001057 +xref: FBbt:00001057 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:87657 xref: MAT:0000176 xref: MIAA:0000176 @@ -12543,7 +12555,7 @@ subset: pheno_slim synonym: "epithelial tissue of iris" EXACT [OBOL:automatic] synonym: "epithelium of iris" EXACT [OBOL:automatic] synonym: "epithelium pigmentosum (iris)" EXACT [FMA:58517] -synonym: "epithelium pigmentosum iridis" EXACT LATIN [FMA:58517, FMA:TA] +synonym: "epithelium pigmentosum iridis" EXACT OMO:0003011 [FMA:58517, FMA:TA] synonym: "iris epithelial tissue" EXACT [OBOL:automatic] synonym: "iris epithelium" EXACT [FMA:58517] synonym: "iris pigmented epithelium" RELATED [MA:0002826] @@ -12572,7 +12584,7 @@ subset: vertebrate_core synonym: "blastocyst" RELATED [] synonym: "ectoblast" RELATED [MP:0003886] synonym: "epiblast" EXACT [VHOG:0000243] -synonym: "epiblastus" RELATED LATIN [Wikipedia:Epiblast] +synonym: "epiblastus" RELATED OMO:0003011 [Wikipedia:Epiblast] synonym: "primitive ectoderm" RELATED [VHOG:0000243] xref: BTO:0004593 xref: FMA:296704 @@ -12883,7 +12895,7 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "lens placodes" RELATED OMO:0003004 [ZFA:0000122] -synonym: "placoda lentis" RELATED LATIN [Wikipedia:Lens_placode] +synonym: "placoda lentis" RELATED OMO:0003011 [Wikipedia:Lens_placode] xref: AAO:0011055 xref: EFO:0003494 xref: EHDAA2:0000982 @@ -12918,7 +12930,7 @@ def: "A region of embryonic ectodermal cells that lie directly above the notocho subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "lamina neuralis" RELATED LATIN [Wikipedia:Neural_plate] +synonym: "lamina neuralis" RELATED OMO:0003011 [Wikipedia:Neural_plate] synonym: "presumptive central nervous system" RELATED [] xref: AAO:0011072 xref: BTO:0001765 @@ -12928,7 +12940,7 @@ xref: EHDAA:346 xref: EHDAA:902 xref: EMAPA:35593 xref: FMA:293879 -xref: MESH:D054258 +xref: MESH:D054258 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: NCIT:C34225 xref: neuronames:1362 xref: RETIRED_EHDAA2:0001252 @@ -12971,7 +12983,7 @@ def: "The paraxial mesoderm is the mesoderm located bilaterally adjacent to the subset: efo_slim subset: uberon_slim subset: vertebrate_core -synonym: "mesoderma paraxiale" RELATED LATIN [Wikipedia:Paraxial_mesoderm] +synonym: "mesoderma paraxiale" RELATED OMO:0003011 [Wikipedia:Paraxial_mesoderm] synonym: "paraxial mesenchyme" EXACT [https://github.com/obophenotype/uberon/issues/30, https://github.com/obophenotype/uberon/wiki/The-neural-crest, ZFA:0000255] synonym: "somitic mesoderm" EXACT [ISBN:9780878932504] xref: AAO:0010568 @@ -13025,7 +13037,7 @@ synonym: "lateral mesoderm" EXACT [GO:0048368] synonym: "lateral plate" RELATED [] synonym: "lateral plate mesenchyme" RELATED [EHDAA2:0000919] synonym: "LPM" EXACT OMO:0003000 [ZFA:0000121] -synonym: "mesoderma laminae lateralis" RELATED LATIN [Wikipedia:Lateral_plate_mesoderm] +synonym: "mesoderma laminae lateralis" RELATED OMO:0003011 [Wikipedia:Lateral_plate_mesoderm] xref: AAO:0010574 xref: EHDAA2:0000919 xref: EHDAA:379 @@ -13086,10 +13098,10 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "sclerotomes" EXACT OMO:0003004 [TAO:0001080] -synonym: "sclerotomus" RELATED LATIN [Wikipedia:Sclerotome] +synonym: "sclerotomus" RELATED OMO:0003011 [Wikipedia:Sclerotome] xref: AAO:0010571 xref: AEO:0000212 -xref: BTO:0006255 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: BTO:0006255 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: EHDAA2:0003439 xref: EMAPA:31159 xref: FMA:295652 @@ -13118,7 +13130,7 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "optic stalks" RELATED OMO:0003004 [ZFA:0000137] -synonym: "pedunculus opticus" RELATED LATIN [Wikipedia:Optic_stalk] +synonym: "pedunculus opticus" RELATED OMO:0003011 [Wikipedia:Optic_stalk] xref: AAO:0011077 xref: EHDAA2:0001318 xref: EHDAA:3816 @@ -13150,7 +13162,7 @@ subset: vertebrate_core synonym: "cephalic neural crest" EXACT [EMAPA:16091] synonym: "CNC" EXACT OMO:0003000 [XAO:0001001] synonym: "cranial NCC population" EXACT [] -synonym: "crista neuralis cranialis" RELATED LATIN [Wikipedia:Cranial_neural_crest] +synonym: "crista neuralis cranialis" RELATED OMO:0003011 [Wikipedia:Cranial_neural_crest] synonym: "head crest" RELATED [] synonym: "head NCC population" EXACT [] synonym: "head neural crest" RELATED [] @@ -13201,7 +13213,7 @@ def: "Portion of tissue composed of mesenchymal cells (motile cells that develop subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "mesenchyma" RELATED LATIN [Wikipedia:Mesenchyme] +synonym: "mesenchyma" RELATED OMO:0003011 [Wikipedia:Mesenchyme] synonym: "mesenchymal tissue" EXACT [] synonym: "mesenchyme tissue" EXACT [] synonym: "portion of mesenchymal tissue" EXACT [] @@ -13512,7 +13524,7 @@ synonym: "neural retina" EXACT [XAO:0003216, ZFA:0000046] synonym: "neural retinal epithelium" RELATED [MA:000027] synonym: "neuroretina" EXACT [ZFA:0000046] synonym: "stratum nervosum (retina)" EXACT [FMA:58628] -synonym: "stratum nervosum retinae" EXACT LATIN [FMA:58628, FMA:TA] +synonym: "stratum nervosum retinae" EXACT OMO:0003011 [FMA:58628, FMA:TA] xref: AAO:0011095 xref: BTO:0000929 xref: CALOHA:TS-0685 @@ -13546,7 +13558,7 @@ def: "Epithelial tubes transport gases, liquids and cells from one site to anoth synonym: "epithelial or endothelial tube" EXACT [] xref: AEO:0000114 xref: EHDAA2:0003114 -xref: FBbt:00007474 +xref: FBbt:00007474 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0000025 ! tube is_a: UBERON:0000483 ! epithelium intersection_of: UBERON:0000483 ! epithelium @@ -13913,7 +13925,7 @@ subset: vertebrate_core synonym: "Descemet membrane" EXACT [] synonym: "Descemet's posterior elastic lamina" EXACT [FMA:58309] synonym: "lamina limitans posterior" EXACT [FMA:58309] -synonym: "lamina limitans posterior corneae" EXACT LATIN [FMA:58309, FMA:TA] +synonym: "lamina limitans posterior corneae" EXACT OMO:0003011 [FMA:58309, FMA:TA] synonym: "posterior limiting lamina" EXACT [MA:0001246] synonym: "posterior limiting lamina of cornea" EXACT [FMA:58309] synonym: "posterior limiting membrane" EXACT [ZFA:0001686] @@ -13957,8 +13969,8 @@ synonym: "Bowman's anterior elastic lamina" EXACT [FMA:58273] synonym: "Bowman's layer" EXACT [FMA:58273] synonym: "Bowman's membrane" EXACT [FMA:58273] synonym: "lamina limitans anterior (cornea)" EXACT [FMA:58273] -synonym: "lamina limitans anterior corneae" EXACT LATIN [FMA:58273, FMA:TA] -synonym: "Reichert's membrane" RELATED DUBIOUS [http://sourceforge.net/tracker/?func=detail&aid=2956371&group_id=76834&atid=974957] +synonym: "lamina limitans anterior corneae" EXACT OMO:0003011 [FMA:58273, FMA:TA] +synonym: "Reichert's membrane" RELATED OMO:0003002 [http://sourceforge.net/tracker/?func=detail&aid=2956371&group_id=76834&atid=974957] xref: FMA:58273 xref: MA:0001240 xref: NCIT:C32226 @@ -14066,6 +14078,7 @@ id: UBERON:0004638 name: blood vessel endothelium namespace: uberon def: "An endothelium that lines the blood vasculature. Other endothelia may line lymph vessels, the heart." [https://orcid.org/0000-0002-6601-2165] +subset: human_reference_atlas subset: pheno_slim subset: vertebrate_core xref: BTO:0000766 @@ -14080,6 +14093,7 @@ is_a: UBERON:0004852 ! cardiovascular system endothelium intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:0001981 ! blood vessel relationship: part_of UBERON:0001981 ! blood vessel +relationship: present_in_taxon NCBITaxon:9606 [Term] id: UBERON:0004716 @@ -14148,7 +14162,7 @@ synonym: "trilaminar disk" RELATED [https://orcid.org/0000-0002-6601-2165] synonym: "trilaminar germ" RELATED [https://orcid.org/0000-0002-6601-2165] xref: BILA:0000060 xref: BTO:0001403 -xref: FBbt:00005317 +xref: FBbt:00005317 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:293108 xref: GAID:1302 xref: MESH:D005775 @@ -14279,7 +14293,7 @@ namespace: uberon def: "Anatomical structure that connects two or more adjacent skeletal elements or hardened body parts." [http://orcid.org/0000-0002-6601-2165] subset: grouping_class synonym: "joint" NARROW [] -xref: FBbt:00005811 +xref: FBbt:00005811 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0034921 ! multi organ part structure relationship: part_of UBERON:0004770 ! articular system @@ -14295,7 +14309,7 @@ synonym: "gut section" RELATED [FBbt:00100315] synonym: "intestinal tract" RELATED [] synonym: "segment of intestinal tract" RELATED [] synonym: "subdivision of alimentary system" RELATED [FMA:71131] -xref: FBbt:00100315 +xref: FBbt:00100315 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:71131 is_a: UBERON:0013522 ! subdivision of tube intersection_of: UBERON:0013522 ! subdivision of tube @@ -14418,7 +14432,7 @@ synonym: "multi-cell-component structure" EXACT [CARO:0001000] synonym: "multi-cell-part structure" EXACT [CARO:0001000] xref: AAO:0011000 xref: CARO:0001000 -xref: FBbt:00007060 +xref: FBbt:00007060 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:83115 is_a: UBERON:0000061 ! anatomical structure relationship: composed_primarily_of GO:0005575 ! cellular_component @@ -14551,7 +14565,7 @@ xref: EHDAA:5526 xref: EMAPA:17082 xref: HBA:9512 xref: MA:0000205 -xref: MESH:D054024 +xref: MESH:D054024 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: VHOG:0000456 xref: Wikipedia:Myelencephalon is_a: UBERON:0004121 ! ectoderm-derived structure @@ -14584,7 +14598,7 @@ name: photoreceptor array namespace: uberon def: "An array of photoreceptors and any supporting cells found in an eye." [https://orcid.org/0000-0002-6601-2165] synonym: "light-sensitive tissue" EXACT [] -xref: FBbt:00004200 +xref: FBbt:00004200 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0004923 ! organ component layer intersection_of: UBERON:0004923 ! organ component layer intersection_of: composed_primarily_of CL:0000210 ! photoreceptor cell @@ -14616,7 +14630,7 @@ synonym: "developmental tissue" RELATED [MIAA:0000019] xref: AEO:0000125 xref: CALOHA:TS-2122 xref: EHDAA2:0003125 -xref: FBbt:00007006 +xref: FBbt:00007006 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:292313 xref: MIAA:0000019 is_a: UBERON:0000465 ! material anatomical entity @@ -14724,7 +14738,7 @@ def: "Multi-tissue structure that arises from the heart rudiment and will become subset: vertebrate_core synonym: "early primitive heart tube" NARROW [EMAPA:16208] synonym: "primitive heart tube" EXACT [EMAPA:16215] -xref: BTO:0006179 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: BTO:0006179 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: EHDAA2:0001512 xref: EHDAA:424 xref: EHDAA:436 @@ -14776,7 +14790,7 @@ namespace: uberon def: "An acellular membrane that is part of the epithelium, lies adjacent to the epithelial cells, and is the fusion of the the basal lamina and the reticular lamina." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Basement_membrane] synonym: "basement membrane" RELATED [FMA:63872] synonym: "basement membrane of connective tissue" EXACT [FMA:63872] -synonym: "membrana basalis" EXACT LATIN [Wikipedia:Basement_membrane] +synonym: "membrana basalis" EXACT OMO:0003011 [Wikipedia:Basement_membrane] xref: AAO:0010596 xref: FMA:63872 xref: GAID:915 @@ -14843,7 +14857,7 @@ def: "Subdivision of skeleton which consists of cranial skeleton, set of all ver subset: human_reference_atlas subset: pheno_slim subset: uberon_slim -synonym: "skeleton axiale" RELATED LATIN [Wikipedia:Axial_skeleton] +synonym: "skeleton axiale" RELATED OMO:0003011 [Wikipedia:Axial_skeleton] xref: AAO:0000963 xref: EMAPA:17214 xref: EMAPA:18043 @@ -14871,8 +14885,8 @@ def: "A threadlike extension of a nerve cell and consists of an axon and myelin subset: human_reference_atlas synonym: "nerve fibers" RELATED OMO:0003004 [BAMS:nfi] synonym: "nerve fibre" EXACT [FMA:5914] -synonym: "neurofibra" EXACT LATIN [FMA:5914, FMA:TA] -synonym: "neurofibra" RELATED LATIN [Wikipedia:Nerve_fiber] +synonym: "neurofibra" EXACT OMO:0003011 [FMA:5914, FMA:TA] +synonym: "neurofibra" RELATED OMO:0003011 [Wikipedia:Nerve_fiber] synonym: "neurofibrum" EXACT [FMA:5914] xref: BAMS:nfi xref: FMA:5914 @@ -15620,7 +15634,7 @@ synonym: "organ field" RELATED [] xref: AEO:0000170 xref: EFO:0001649 xref: EHDAA2:0003170 -xref: FBbt:00005426 +xref: FBbt:00005426 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: Wikipedia:Anlage_(biology) is_a: UBERON:0000479 {source="FBbt"} ! tissue is_a: UBERON:0005423 {source="AEO", source="FBbt"} ! developing anatomical structure @@ -15824,7 +15838,7 @@ subset: common_anatomy subset: upper_level synonym: "multicellular structure" EXACT [FBbt:00100313] xref: CARO:0010000 -xref: FBbt:00100313 +xref: FBbt:00100313 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0000061 ! anatomical structure intersection_of: UBERON:0000061 ! anatomical structure intersection_of: has_quality PATO:0001993 ! multicellular @@ -15990,8 +16004,8 @@ def: "The ciliary processes are formed by the inward folding of the various laye synonym: "ciliary process" RELATED [Wikipedia:Ciliary_processes] synonym: "ciliary processes" EXACT [FMA:76551] synonym: "ciliary processes set" EXACT [FMA:76551] -synonym: "processus ciliares" EXACT LATIN [FMA:TA] -synonym: "processus ciliares" RELATED LATIN [Wikipedia:Ciliary_processes] +synonym: "processus ciliares" EXACT OMO:0003011 [FMA:TA] +synonym: "processus ciliares" RELATED OMO:0003011 [Wikipedia:Ciliary_processes] synonym: "set of ciliary processes" EXACT [FMA:76551] xref: FMA:76551 xref: SCTID:280860001 @@ -16062,8 +16076,9 @@ name: organ system subdivision namespace: uberon def: "A subdivision of an anatomical system." [http://orcid.org/0000-0002-6601-2165] subset: common_anatomy +subset: human_reference_atlas subset: upper_level -xref: FBbt:00007330 +xref: FBbt:00007330 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:67509 xref: SCTID:91690000 is_a: UBERON:0010000 {source="FBbt"} ! multicellular anatomical structure @@ -16071,6 +16086,7 @@ relationship: part_of UBERON:0000467 ! anatomical system relationship: present_in_taxon NCBITaxon:33090 relationship: present_in_taxon NCBITaxon:33208 ! Metazoa relationship: present_in_taxon NCBITaxon:4751 +relationship: present_in_taxon NCBITaxon:9606 [Term] id: UBERON:0011222 @@ -16156,8 +16172,8 @@ id: UBERON:0011825 name: loose connective tissue namespace: uberon def: "Irregular connective tissue, the intercellular matrix of which contains a sparse irregular network of collagen and elastic fiber bundles. Examples: areolar tissue, neuroglial tissue, mucoid tissue." [FMA:19783] -synonym: "textus connectivus collagenosus laxus" EXACT LATIN [FMA:19783, FMA:TA] -synonym: "textus connectivus laxus" EXACT LATIN [FMA:19783, FMA:TA] +synonym: "textus connectivus collagenosus laxus" EXACT OMO:0003011 [FMA:19783, FMA:TA] +synonym: "textus connectivus laxus" EXACT OMO:0003011 [FMA:19783, FMA:TA] xref: FMA:19783 xref: NCIT:C33007 xref: UMLS:C1253917 {source="ncithesaurus:Loose_Connective_Tissue"} @@ -16290,7 +16306,6 @@ id: UBERON:0013702 name: body proper namespace: uberon def: "The region of the organism associated with the visceral organs." [AEO:0000103] -subset: human_reference_atlas subset: non_informative synonym: "body" RELATED [AEO:0000103] synonym: "whole body" RELATED [BTO:0001489] @@ -16300,7 +16315,6 @@ xref: EMAPA:36031 xref: FMA:231424 is_a: UBERON:0000475 {source="AEO"} ! organism subdivision relationship: part_of UBERON:0013701 ! main body axis -relationship: present_in_taxon NCBITaxon:9606 property_value: UBPROP:0000001 "Cardinal body part, which consists of a maximal set of diverse subclasses of organ and organ part spatially associated with the vertebral column and ribcage. Examples: There is only one body proper[FMA:231424]." xsd:string {source="FMA:231424"} [Term] @@ -16341,7 +16355,7 @@ name: non-connected functional system namespace: uberon def: "An anatomical group whose component structures share a common function." [AEO:0000093, AEO:JB, FBbt:00007278, FBC:DOS] xref: AEO:0000093 -xref: FBbt:00007278 +xref: FBbt:00007278 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0034923 ! disconnected anatomical group [Term] @@ -16581,7 +16595,7 @@ namespace: uberon def: "Material anatomical entity consisting of multiple anatomical structures that are not connected to each other." [CARO:0020000] subset: common_anatomy xref: CARO:0020000 -xref: FBbt:00007276 +xref: FBbt:00007276 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0000465 {source="CARO"} ! material anatomical entity relationship: composed_primarily_of UBERON:0000061 ! anatomical structure relationship: has_component UBERON:0000061 {minCardinality="2"} ! anatomical structure @@ -16611,13 +16625,13 @@ def: "The parts of the orbital region that are outside of the the eyeball, inclu synonym: "accessory parts of orbital region" RELATED [] synonym: "accessory visual structures" RELATED [FMA:76554, Wikipedia:Accessory_visual_structures] synonym: "accessory visual structures set" RELATED [FMA:76554] -synonym: "adnexa oculi" EXACT LATIN [http://medical-dictionary.thefreedictionary.com/ocular+adnexa] +synonym: "adnexa oculi" EXACT OMO:0003011 [http://medical-dictionary.thefreedictionary.com/ocular+adnexa] synonym: "adnexal parts of orbital region" RELATED [] synonym: "appendage of eye" RELATED [http://medical-dictionary.thefreedictionary.com/ocular+adnexa] synonym: "appendages of the eye" RELATED OMO:0003004 [http://medical-dictionary.thefreedictionary.com/ocular+adnexa] synonym: "eye adnexa" RELATED [] synonym: "set of accessory visual structures" RELATED [FMA:76554] -synonym: "structurae oculi accessoriae" RELATED LATIN [Wikipedia:Accessory_visual_structures] +synonym: "structurae oculi accessoriae" RELATED OMO:0003011 [Wikipedia:Accessory_visual_structures] xref: FMA:76554 xref: NCIT:C32574 xref: SCTID:120612006 @@ -17056,20 +17070,6 @@ property_value: seeAlso "https://github.com/obophenotype/uberon/wiki/Part-disjoi is_a: RO:0002323 ! mereotopologically related to expand_expression_to: "BFO_0000051 exactly 0 (BFO_0000050 some ?Y)" [] -[Typedef] -id: RO:0002203 -name: develops into -def: "inverse of develops from" [] -subset: RO:0002259 -property_value: IAO:0000114 IAO:0000125 -property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 -property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172 -property_value: IAO:0000117 https://orcid.org/0000-0003-1980-3228 -is_transitive: true -is_a: has_potential_to_develop_into ! has potential to develop into -is_a: RO:0002286 ! developmentally succeeded by -is_a: RO:0002388 ! has potential to directly develop into - [Typedef] id: RO:0002206 name: expressed in @@ -17090,7 +17090,7 @@ def: "inverse of directly develops from" [] subset: RO:0002259 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000118 "developmental precursor of" xsd:string -is_a: RO:0002203 ! develops into +is_a: develops_into ! develops into [Typedef] id: RO:0002222 @@ -17120,7 +17120,7 @@ def: "inverse of has developmental contribution from" [] subset: RO:0002259 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 -holds_over_chain: RO:0002203 part_of +holds_over_chain: develops_into part_of is_a: has_potential_to_developmentally_contribute_to ! has potential to developmentally contribute to is_a: RO:0002286 ! developmentally succeeded by @@ -18406,7 +18406,7 @@ range: BFO:0000004 ! independent continuant is_transitive: true is_a: has_developmental_contribution_from ! has developmental contribution from is_a: RO:0002258 ! developmentally preceded by -inverse_of: RO:0002203 ! develops into +inverse_of: develops_into ! develops into [Typedef] id: develops_from_part_of @@ -18433,6 +18433,22 @@ domain: UBERON:0001062 ! anatomical entity holds_over_chain: directly_develops_from located_in is_a: RO:0002258 ! developmentally preceded by +[Typedef] +id: develops_into +name: develops into +namespace: uberon +def: "inverse of develops from" [] +subset: RO:0002259 +xref: RO:0002203 +property_value: IAO:0000114 IAO:0000125 +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 +property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172 +property_value: IAO:0000117 https://orcid.org/0000-0003-1980-3228 +is_transitive: true +is_a: has_potential_to_develop_into ! has potential to develop into +is_a: RO:0002286 ! developmentally succeeded by +is_a: RO:0002388 ! has potential to directly develop into + [Typedef] id: directly_develops_from name: directly develops from @@ -18767,7 +18783,7 @@ is_a: RO:0002479 ! has part that occurs in id: has_high_plasma_membrane_amount name: obsolete has_high_plasma_membrane_amount def: "OBSOLETE A relation between a cell and molecule or complex such that every instance of the cell has a high number of instances of that molecule expressed on the cell surface. For the formal definition, see Masci et al (PMID:19243617)." [PMID:19243617] -comment: Replaced with RO:0015015, see https://github.com/obophenotype/cell-ontology/issues/1481 +property_value: term_tracker_item https://github.com/obophenotype/cell-ontology/issues/1481 is_obsolete: true replaced_by: RO:0015015 @@ -18794,7 +18810,7 @@ inverse_of: input_of ! input of id: has_low_plasma_membrane_amount name: obsolete has_low_plasma_membrane_amount def: "OBSOLETE A relation between a cell and molecule or complex such that every instance of the cell has a low number of instances of that molecule expressed on the cell surface. For the formal definition, see Masci et al (PMID:19243617)." [PMID:19243617] -comment: Replaced with RO:0015016, see https://github.com/obophenotype/cell-ontology/issues/1481 +property_value: term_tracker_item https://github.com/obophenotype/cell-ontology/issues/1481 is_obsolete: true replaced_by: RO:0015016 @@ -20183,21 +20199,21 @@ is_a: develops_from ! develops from id: transitively_anteriorly_connected_to name: transitively anteriorly connected to namespace: uberon -def: "." [http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern] +property_value: seeAlso "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" xsd:anyURI is_transitive: true [Typedef] id: transitively_distally_connected_to name: transitively distally connected to namespace: uberon -def: "." [http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern] +property_value: seeAlso "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" xsd:anyURI is_transitive: true [Typedef] id: transitively_proximally_connected_to name: transitively proximally connected to namespace: uberon -def: "." [http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern] +property_value: seeAlso "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" xsd:anyURI is_transitive: true [Typedef] diff --git a/subsets/eye_upper_slim.owl b/subsets/eye_upper_slim.owl index fec82a604..379bb2999 100644 --- a/subsets/eye_upper_slim.owl +++ b/subsets/eye_upper_slim.owl @@ -18,6 +18,7 @@ xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#" xmlns:skos="http://www.w3.org/2004/02/skos/core#" xmlns:swrl="http://www.w3.org/2003/11/swrl#" + xmlns:sssom="https://w3id.org/sssom/" xmlns:swrla="http://swrl.stanford.edu/ontologies/3.3/swrla.owl#" xmlns:swrlb="http://www.w3.org/2003/11/swrlb#" xmlns:terms="http://purl.org/dc/terms/" @@ -29,8 +30,8 @@ xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#" xmlns:ncbitaxon="http://purl.obolibrary.org/obo/ncbitaxon#"> - - 2024-01-04 + + 2024-02-13 @@ -315,6 +316,14 @@ Annotations: IAO_0000424 "http://purl.obolibrary.org/obo/BFO_0000051 some ( + + + + + + + + @@ -337,6 +346,14 @@ Annotations: IAO_0000424 "http://purl.obolibrary.org/obo/BFO_0000051 some ( + + + + + + + + @@ -846,25 +863,25 @@ WHERE { - + - + - + - + - + - + @@ -1071,14 +1088,6 @@ WHERE { - - - - - - - - @@ -1103,14 +1112,6 @@ WHERE { - - - - - - - - @@ -1942,6 +1943,24 @@ WHERE { + + + + + + + + + + + + + + + + + + - - - - - - - - - - - - - - - - - - - - - A nucleus size quality which is relatively high compared to the amount of cytoplasm present in the same cell. - - 2009-12-23T10:53:24Z - increased nucleus size - - - - - A nucleus size quality which is relatively high compared to the amount of cytoplasm present in the same cell. - GOC:tfm - - - - @@ -13758,6 +13803,7 @@ plexiform layer. An epithelial cell that is part of the conjunctiva. FMA:70552 epithelial cell of conjunctiva + conjunctival epithelial cell @@ -13806,6 +13852,7 @@ plexiform layer. A smooth muscle cell that is part of the ciliary body. FMA:70610 smooth muscle cell of ciliary body + ciliary muscle cell @@ -14718,7 +14765,7 @@ plexiform layer. - A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex). + A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex). https://github.com/geneontology/go-ontology/issues/17729 GO:0008372 NIF_Subcellular:sao1337158144 @@ -14739,7 +14786,7 @@ plexiform layer. - A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex). + A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex). GOC:pdt @@ -14769,8 +14816,8 @@ plexiform layer. + - Note that this term is intended to annotate gene products that are not attached to the cell surface. For gene products from multicellular organisms which are secreted from a cell but retained within the organism (i.e. released into the interstitial fluid or blood), consider the cellular component term 'extracellular space ; GO:0005615'. extracellular region @@ -14815,32 +14862,32 @@ plexiform layer. - - + + A protein complex consisting of three collagen chains assembled into a left-handed triple helix. These trimers typically assemble into higher order structures. Wikipedia:Collagen cellular_component GO:0005581 collagen trimer - + - + - + PMID:12382326 - + PMID:12382326 @@ -14922,7 +14969,7 @@ plexiform layer. - + Note that for multicellular organisms, the extracellular space refers to everything outside a cell, but still within the organism (excluding the extracellular matrix). Gene products from a multi-cellular organism that are secreted from a cell into the interstitial fluid or blood can therefore be annotated to this term. extracellular space @@ -15062,8 +15109,8 @@ plexiform layer. + - Chromosomes include parts that are not part of the chromatin. Examples include the kinetochore. chromosome @@ -15129,8 +15176,8 @@ plexiform layer. + - cytoplasm @@ -15168,8 +15215,8 @@ plexiform layer. + - ribosome @@ -15228,8 +15275,8 @@ plexiform layer. + - plasma membrane @@ -15336,7 +15383,7 @@ plexiform layer. - + translation @@ -15464,7 +15511,7 @@ plexiform layer. - + Note that this term should not be used for direct annotation. It should be possible to make a more specific annotation to one of the children of this term, for e.g. to transmembrane transport, to microtubule-based transport or to vesicle-mediated transport. transport @@ -16486,7 +16533,7 @@ plexiform layer. necrosis GO:0008219 - This term should not be used for direct annotation, it is currently kept in GO as a placeholder for describing cell death phenotypes in uPHENO. When information is provided on a programmed cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'). Unintentional cell death, i.e. cell death caused by injury, ageing, or cell phenotypes observed as a result of a pathological mutation in an essential gene should NOT be annotated using GO terms. + This term should not be used for direct annotation, it is currently kept in GO as a placeholder for describing cell death phenotypes in uPHENO. When information is provided on a programmed cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'). Unintentional cell death, i.e. cell death caused by injury, ageing, or cell phenotypes observed as a result of a pathological mutation in an essential gene should NOT be annotated using GO terms. cell death @@ -17022,7 +17069,7 @@ plexiform layer. - + Note that this term should be used to annotate gene products in the organism undergoing the programmed cell death. To annotate genes in another organism whose products modulate programmed cell death in a host organism, consider the term 'modulation by symbiont of host programmed cell death ; GO:0052040'. Also, note that 'programmed cell death ; GO:0012501' should be used to refer to instances of caspase-independent cell death mechanisms, in the absence of further indications on the process taking place. At present, caspase-independent cell death is not yet represented in GO due to the lack of consensus and in-depth research on the topic. 'programmed cell death ; GO:0012501' may also be used to annotate gene products in taxa where apoptosis as defined in GO:0006915 does not occur, such as plants. You may also consider these specific children: GO:0097468 'programmed cell death in response to reactive oxygen species' (with descendants GO:0010421 'hydrogen peroxide-mediated programmed cell death' and GO:0010343 'singlet oxygen-mediated programmed cell death'), and GO:0009626 'plant-type hypersensitive response' and its children. programmed cell death @@ -17758,8 +17805,8 @@ plexiform layer. + - Note that a signal is any variable property or parameter that serves to convey information, and may be a physical entity such as a gene product or small molecule, a photon, or a change in state such as movement or voltage change. signaling @@ -17851,7 +17898,7 @@ plexiform layer. cell projection organization and biogenesis cell surface structure organization and biogenesis GO:0030030 - + cell projection organization @@ -18373,7 +18420,7 @@ plexiform layer. - + extracellular matrix @@ -19230,7 +19277,7 @@ plexiform layer. - + cell projection @@ -19375,6 +19422,7 @@ plexiform layer. The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. + https://github.com/geneontology/go-ontology/issues/26424 GO:0034960 GO:0043283 GO:0044259 @@ -19384,6 +19432,7 @@ plexiform layer. multicellular organismal macromolecule metabolic process biological_process GO:0043170 + macromolecule metabolic process @@ -19471,7 +19520,7 @@ plexiform layer. - + organelle @@ -19964,9 +20013,11 @@ plexiform layer. The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism. + https://github.com/geneontology/go-ontology/issues/26424 primary metabolism biological_process GO:0044238 + primary metabolic process @@ -20543,9 +20594,11 @@ plexiform layer. The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. + https://github.com/geneontology/go-ontology/issues/26424 development of an anatomical structure biological_process GO:0048856 + @@ -20593,7 +20646,7 @@ plexiform layer. - + cell motility @@ -20804,7 +20857,7 @@ plexiform layer. - + Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. response to stimulus @@ -21672,7 +21725,7 @@ plexiform layer. - + protein-containing complex assembly @@ -21890,6 +21943,7 @@ plexiform layer. The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon. + https://github.com/geneontology/go-ontology/issues/26424 mah 2010-03-08T03:32:18Z organic molecular entity metabolic process @@ -21897,6 +21951,7 @@ plexiform layer. organic substance metabolism biological_process GO:0071704 + organic substance metabolic process @@ -22010,7 +22065,7 @@ plexiform layer. - The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures. + The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures. mah 2010-10-04T01:51:47Z cellular_component @@ -22021,7 +22076,7 @@ plexiform layer. - The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures. + The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures. GOC:pdt @@ -22929,6 +22984,7 @@ plexiform layer. A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex but below that of an anatomical system. Or, a substance produced by a cellular organism with granularity above the level of a protein complex. https://github.com/geneontology/go-ontology/issues/24200 + https://github.com/geneontology/go-ontology/issues/26424 kmv 2019-08-12T18:01:37Z cellular_component @@ -24213,57 +24269,6 @@ plexiform layer. - - - - - quality - PATO:0000068 - TODO: define this or obsolete it and move children somewhere else. - qualitative - - - - - - - - - A quality inhering in a bearer by virtue of the whether the bearer differs from normal or average. - quality - PATO:0000069 - - deviation (from_normal) - - - - - A quality inhering in a bearer by virtue of the whether the bearer differs from normal or average. - PATOC:GVG - - - - - - - - - A morphology quality inhering in a bearer by virtue of the bearer's physical magnitude. - quality - PATO:0000117 - - - size - - - - - A morphology quality inhering in a bearer by virtue of the bearer's physical magnitude. - WordNet:WordNet - - - - @@ -24359,67 +24364,6 @@ plexiform layer. - - - - - A quality inhering in a bearer by virtue of the bearer's exhibiting no deviation from normal or average. - - quality - average - PATO:0000461 - - - - normal - - - - - A quality inhering in a bearer by virtue of the bearer's exhibiting no deviation from normal or average. - PATOC:GVG - - - - - - - - - - - - - - - - - - - - - A size quality which is relatively high. - - PATO:0001202 - quality - big - enlarged - expanded - great - large - PATO:0000586 - - increased size - - - - - A size quality which is relatively high. - PATOC:GVG - - - - @@ -25239,77 +25183,6 @@ plexiform layer. - - - - - - - - - - - - - - - - - - - - - - A quality that has a value that is increased compared to normal or average. - - - 2011-06-16T06:39:43Z - quality - PATO:0002300 - increased quality - - - - - A quality that has a value that is increased compared to normal or average. - PATOC:GVG - - - - - - - - - - - - - - - - - - - - - A quality of an object that has a value that is increased compared to normal or average. - - - 2011-06-16T06:54:01Z - quality - PATO:0002305 - increased object quality - - - - - A quality of an object that has a value that is increased compared to normal or average. - PATOC:GVG - - - - @@ -25461,6 +25334,28 @@ plexiform layer. + + + + + A quality inhering in a cell by virtue of the cell having a high nuclear/cytoplasmic ratio. + http://orcid.org/0000-0001-5208-3432 + high N:C ratio + quality + PATO:0040072 + A high nuclear/cytolasmic ratio is 70% or higher. + high nuclear/cytoplasmic ratio + + + + + A quality inhering in a cell by virtue of the cell having a high nuclear/cytoplasmic ratio. + Wikipedia:NC_ratio&oldid=931936284 + http://lymerick.net/blood-cells.pdf + + + + @@ -26727,7 +26622,7 @@ plexiform layer. - + @@ -26768,14 +26663,14 @@ plexiform layer. camera-type eye - + - + definitional @@ -26835,7 +26730,7 @@ plexiform layer. regio orbitalis FMA:54448 FMA:TA - + @@ -26927,6 +26822,12 @@ plexiform layer. https://github.com/obophenotype/uberon/issues/549 https://orcid.org/0000-0002-6601-2165 + + + + FBbt:00005155 + + @@ -27234,7 +27135,7 @@ plexiform layer. tunica serosa FMA:9581 - + @@ -27406,6 +27307,12 @@ plexiform layer. Material anatomical entity that is a single connected structure with inherent 3D shape generated by coordinated expression of the organism's own genome. CARO:0000003 + + + + FBbt:00007001 + + @@ -27874,7 +27781,7 @@ plexiform layer. - + The surface (external) layer of ectoderm which begins to proliferate shortly after separation from the neuroectoderm. merge with non-neural. In vertebrates, the ectoderm has three parts: external ectoderm (also known as surface ectoderm), the neurectoderm (neural crest, and neural tube) @@ -27900,7 +27807,7 @@ plexiform layer. external ectoderm http://upload.wikimedia.org/wikipedia/commons/1/1d/Ectoderm.png - + @@ -27913,7 +27820,7 @@ plexiform layer. - + EHDAA2 @@ -27927,7 +27834,9 @@ plexiform layer. BTO:0006242 - https://orcid.org/0000-0003-4423-4370 + + + https://github.com/biopragmatics/biomappings @@ -28146,7 +28055,9 @@ plexiform layer. IDOMAL:0000302 - https://orcid.org/0000-0003-4423-4370 + + + https://github.com/biopragmatics/biomappings @@ -28171,7 +28082,7 @@ plexiform layer. zygotum Wikipedia:Zygote - + @@ -28295,7 +28206,7 @@ plexiform layer. - + @@ -28331,14 +28242,14 @@ plexiform layer. gastrula stage - + - + BILS @@ -28521,6 +28432,12 @@ plexiform layer. FBC:DOS FBbt:00005099 + + + + FBbt:00005099 + + @@ -28708,6 +28625,12 @@ plexiform layer. in FMA, the tongue, palate etc are part of the mouth which is itself a subdivision of the face. ZFA includes a separate class 'oral region' which is part of the mouth, but excludes tongue and lips FMA + + + + FBbt:00003126 + + @@ -28715,14 +28638,14 @@ plexiform layer. BTO:0004698 FMA:49184 FMA:TA - + cavital oralis Wikipedia:Mouth - + @@ -28798,15 +28721,15 @@ plexiform layer. - + - - + + A fluid that is composed of blood plasma and erythrocytes. This class excludes blood analogues, such as the insect analog of blood. See UBERON:0000179 haemolymphatic fluid. @@ -28848,34 +28771,34 @@ plexiform layer. blood - + - + - + - + CL:tm - + https://github.com/obophenotype/uberon/issues/1330 - + Bgee:AN @@ -29179,7 +29102,7 @@ plexiform layer. - + @@ -29221,14 +29144,14 @@ plexiform layer. organism substance - + - + this relationship may be too strong and may be weakened in future @@ -29237,6 +29160,12 @@ plexiform layer. Material anatomical entity in a gaseous, liquid, semisolid or solid state; produced by anatomical structures or derived from inhaled and ingested substances that have been modified by anatomical structures as they pass through the body. http://orcid.org/0000-0001-9114-8737 + + + + FBbt:00007019 + + @@ -29315,6 +29244,12 @@ plexiform layer. Non-material anatomical entity of three dimensions, that is generated by morphogenetic or other physiologic processes; is surrounded by one or more anatomical structures; contains one or more organism substances or anatomical structures. http://orcid.org/0000-0001-9114-8737 + + + + FBbt:00007017 + + @@ -29364,6 +29299,12 @@ plexiform layer. Anatomical entity that has mass. http://orcid.org/0000-0001-9114-8737 + + + + FBbt:00007016 + + @@ -29400,6 +29341,12 @@ plexiform layer. Anatomical entity that has no mass. http://orcid.org/0000-0001-9114-8737 + + + + FBbt:00007015 + + @@ -29485,11 +29432,19 @@ plexiform layer. system GO:0048731 + + + + FBbt:00004856 + + IDOMAL:0002460 - https://orcid.org/0000-0003-4423-4370 + + + https://github.com/biopragmatics/biomappings @@ -29588,6 +29543,12 @@ plexiform layer. VHOG:0000671 WBbt:0007833 + + + + FBbt:00000001 + + @@ -29691,6 +29652,12 @@ plexiform layer. CARO:DOS http://orcid.org/0000-0001-9114-8737 + + + + FBbt:00007009 + + @@ -29758,6 +29725,12 @@ plexiform layer. Anatomical structure that consists of cell parts and cell substances and together does not constitute a cell or a tissue. http://orcid.org/0000-0001-9114-8737 + + + + FBbt:00007013 + + @@ -29777,7 +29750,6 @@ plexiform layer. FBbt:00007277 - IDOMAL:0002461 VHOG:0001737 uberon UBERON:0000477 @@ -29794,8 +29766,8 @@ plexiform layer. - IDOMAL:0002461 - https://orcid.org/0000-0003-4423-4370 + FBbt:00007277 + @@ -29866,6 +29838,12 @@ plexiform layer. Multicellular anatomical structure that consists of many cells of one or a few types, arranged in an extracellular matrix such that their long-range organisation is at least partly a repetition of their short-range organisation. CARO:0000043 + + + + FBbt:00007003 + + @@ -29933,6 +29911,12 @@ plexiform layer. CARO:0000055 http://orcid.org/0000-0001-9114-8737 + + + + FBbt:00007010 + + @@ -29971,7 +29955,7 @@ plexiform layer. - + @@ -30015,14 +29999,14 @@ plexiform layer. epithelium https://upload.wikimedia.org/wikipedia/commons/8/8f/Illu_epithelium.jpg - + - + http://palaeos.com/metazoa/porifera/homoscleromorpha.html @@ -30042,6 +30026,12 @@ plexiform layer. ISBN:978-0030259821 Ruppert EE, Fox RS, Barnes RD, Invertebrate zoology: a functional evolutionary approach (2003) p.59 http://bgee.unil.ch/ + + + + FBbt:00007005 + + @@ -30460,11 +30450,19 @@ plexiform layer. Obsoleted in ZFA. Note that embryo is not classified as an embryonic structure - an embryonic structure is only the parts of an embryo ZFA + + + + FBbt:00000052 + + IDOMAL:0000646 - https://orcid.org/0000-0003-4423-4370 + + + https://github.com/biopragmatics/biomappings @@ -30551,6 +30549,12 @@ plexiform layer. embryonic tissue FMA:69069 + + + + FBbt:00000110 + + @@ -30589,7 +30593,7 @@ plexiform layer. - + Primary germ layer that is the outer of the embryo's three germ layers and gives rise to epidermis and neural tissue. Primary germ layer that is the outer of the embryonic germ layers and gives rise to epidermis and neural tissue.[AAO] The Bilateria are triploblastic (with true endoderm, mesoderm, and ectoderm) (...).[well established][VHOG] @@ -30627,14 +30631,14 @@ plexiform layer. ectoderm http://upload.wikimedia.org/wikipedia/commons/1/19/Gray32.png - + - + Bgee:AN @@ -30662,6 +30666,12 @@ plexiform layer. ISBN:978-0878932504 Gilbert SF, Developmental Biology (2006) Limb development and evolution, p.722 http://bgee.unil.ch/ + + + + FBbt:00000111 + + @@ -30687,7 +30697,7 @@ plexiform layer. - + Primary germ layer that lies remote from the surface of the embryo and gives rise to internal tissues such as gut. The Bilateria are triploblastic (with true endoderm, mesoderm, and ectoderm) (...).[well established][VHOG] endodermal @@ -30724,14 +30734,14 @@ plexiform layer. http://upload.wikimedia.org/wikipedia/commons/c/c0/Endoderm2.png http://upload.wikimedia.org/wikipedia/commons/d/df/Gray10.png - + - + Bgee:AN @@ -30750,6 +30760,12 @@ plexiform layer. ISBN:978-0878932504 Gilbert SF, Developmental Biology (2006) Limb development and evolution, p.722 http://bgee.unil.ch/ + + + + FBbt:00000125 + + @@ -30776,7 +30792,7 @@ plexiform layer. - + The middle germ layer of the embryo, between the endoderm and ectoderm. Primary germ layer that is the middle of the embryonic germ layers.[AAO] @@ -30821,7 +30837,7 @@ plexiform layer. mesoderm http://upload.wikimedia.org/wikipedia/commons/e/e8/Mesoderm.png - + @@ -30834,7 +30850,7 @@ plexiform layer. - + Bgee:AN @@ -30868,6 +30884,12 @@ plexiform layer. sponges do not seem to have a mesoderm and accordingly Amphimedon lacks transcription factors involved in mesoderm development (Fkh, Gsc, Twist, Snail)[http://www.nature.com/nature/journal/v466/n7307/full/nature09201.html]. Mesoderm may not be homologous across verteberates https://github.com/obophenotype/uberon/wiki/The-neural-crest + + + + FBbt:00000126 + + @@ -30977,6 +30999,12 @@ plexiform layer. stomodeal-hypophyseal primordium XAO:0000269 + + + + FBbt:00000439 + + @@ -31056,7 +31084,7 @@ plexiform layer. - + @@ -31122,14 +31150,14 @@ plexiform layer. cranial nerve II - + - + EHDAA2 @@ -31212,7 +31240,7 @@ plexiform layer. nervus opticus - + @@ -31220,7 +31248,7 @@ plexiform layer. nervus opticus [II] FMA:50863 FMA:TA - + @@ -31273,7 +31301,7 @@ plexiform layer. - + @@ -31350,14 +31378,14 @@ plexiform layer. https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Heart.glb https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Heart.glb - + - + MA @@ -31435,7 +31463,7 @@ plexiform layer. - + @@ -31460,7 +31488,7 @@ plexiform layer. - + The brain is the center of the nervous system in all vertebrate, and most invertebrate, animals. Some primitive animals such as jellyfish and starfish have a decentralized nervous system without a brain, while sponges lack any nervous system at all. In vertebrates, the brain is located in the head, protected by the skull and close to the primary sensory apparatus of vision, hearing, balance, taste, and smell[WP]. requires review for applicability to invertebrate structures, e.g. synganglion @@ -31523,11 +31551,11 @@ plexiform layer. https://ccf-ontology.hubmapconsortium.org/objects/v1.2/Allen_F_Brain.glb https://ccf-ontology.hubmapconsortium.org/objects/v1.2/Allen_M_Brain.glb - + - + @@ -31540,13 +31568,13 @@ plexiform layer. - + FMA - + Bgee:AN @@ -31590,6 +31618,12 @@ plexiform layer. ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.28, ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.165 http://bgee.unil.ch/ + + + + FBbt:00005095 + + @@ -31804,7 +31838,7 @@ plexiform layer. chiasma opticum Wikipedia:Optic_chiasm - + @@ -31823,14 +31857,14 @@ plexiform layer. chiasma NeuroNames:459 - + chiasma nervorum opticorum NeuroNames:459 - + @@ -31847,9 +31881,9 @@ plexiform layer. - - - + + + @@ -31874,7 +31908,7 @@ plexiform layer. - + @@ -31930,44 +31964,44 @@ plexiform layer. cornea http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg - + - + - + - + - + MA - + MA - + FMA-isa - + definitional @@ -32156,10 +32190,10 @@ plexiform layer. - - - - + + + + The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates. @@ -32210,44 +32244,44 @@ plexiform layer. retina http://upload.wikimedia.org/wikipedia/commons/e/ed/Human_eye_cross-sectional_view_grayscale.png - + - + - + - + - + FMA - + FMA - + FMA - + EHDAA2 @@ -32321,8 +32355,8 @@ plexiform layer. - - + + @@ -32358,24 +32392,24 @@ plexiform layer. eye - + - + - + PMID:21062451 - + PMID:21062451 @@ -32384,6 +32418,12 @@ plexiform layer. An organ that detects light. https://orcid.org/0000-0002-6601-2165 + + + + FBbt:00005162 + + @@ -32605,6 +32645,12 @@ plexiform layer. many anatomy ontologies consider gastrointestinal system synonymous with digestive system. here we follow MA in dividing digestive system into gastrointestinal and hepatobiliary. hepatobiliary includes the liver and biliary tract. species-specific AO classes are categorized according to whether liver is included. For example, XAO includes liver as part of XAO:0000125 alimentary system, so we assume this class is the more generic class MA + + + + FBbt:00005055 + + @@ -32646,6 +32692,7 @@ plexiform layer. We should divest ourselves of the view that earlier vertebrate groups were 'on their way' to becoming mammals, as clearly they were not such visionaries. Neither were their systems 'imperfect' as earlier anatomists thought. Instead, their circulatory systems served them well to address the ecological demands arising from their lifestyles.[well established][VHOG] AAO:0000959 CALOHA:TS-2103 + MESH:D002319 VHOG:0001248 Wikipedia:Circulatory_system uberon @@ -32693,12 +32740,19 @@ plexiform layer. ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.493 http://bgee.unil.ch/ + + + + MESH:D002319 + + https://github.com/biopragmatics/biomappings + systema cardiovasculare Wikipedia:Circulatory_system - + @@ -32779,7 +32833,7 @@ plexiform layer. musculi FMA:32558 FMA:TA - + @@ -32830,13 +32884,14 @@ plexiform layer. - + The nervous system is an organ system containing predominantly neuron and glial cells. In bilaterally symmetrical organism, it is arranged in a network of tree-like structures connected to a central body. The main functions of the nervous system are to regulate and control body functions, and to receive sensory input, process this information, and generate behavior [CUMBO]. + A regulatory system of the body that consists of neurons and neuroglial cells. The nervous system is divided into two parts, the central nervous system (CNS) and the peripheral nervous system (PNS). (Source: BioGlossary, www.Biology-Text.com)[TAO] Anatomical system consisting of nerve bodies and nerve fibers which regulate the response of the body to external and internal stimuli.[AAO] Nervous systems evolved in the ancestor of Eumetazoa.[well established][VHOG] @@ -32876,6 +32931,7 @@ plexiform layer. UBERON:0001016 + @@ -32883,14 +32939,14 @@ plexiform layer. http://upload.wikimedia.org/wikipedia/commons/b/b2/TE-Nervous_system_diagram.svg http://upload.wikimedia.org/wikipedia/commons/b/ba/Nervous_system_diagram.png - + - + Bgee:AN @@ -32933,6 +32989,12 @@ plexiform layer. ISBN:978-0198566694 Schmidt-Rhaesa A, The evolution of organ systems (2007) p.117 http://bgee.unil.ch/ + + + + FBbt:00005093 + + @@ -32956,7 +33018,7 @@ plexiform layer. systema nervosum Wikipedia:Nervous_system - + @@ -32978,9 +33040,10 @@ plexiform layer. - + The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the neural tube derivatives: the brain and spinal cord. In invertebrates it includes central ganglia plus nerve cord. + Part of the nervous system which includes the brain and spinal cord.[AAO] The brain and spinal cord. Kimmel et al, 1995.[TAO] The central nervous system (CNS) is the part of the nervous system which includes the brain, spinal cord, and nerve cell layer of the retina (CUMBO). @@ -33020,12 +33083,13 @@ plexiform layer. UBERON:0001017 + central nervous system - + @@ -33039,7 +33103,7 @@ plexiform layer. - + Bgee:AN @@ -33090,6 +33154,12 @@ plexiform layer. ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.28 (reference 1), ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.165 (reference 2), DOI:10.1016/j.cell.2007.02.040 Denes AS, Jekely G, Steinmetz PRH, Raible F, Snyman H, Prud'homme B, Ferrier DEK, Balavoine G and Arendt D, Molecular architecture of annelid nerve cord supports common origin of nervous system centralization in Bilateria. Cell (2007) (reference 3) http://bgee.unil.ch/ + + + + FBbt:00005094 + + @@ -33109,7 +33179,7 @@ plexiform layer. systema nervosum centrale FMA:55675 FMA:TA - + @@ -33164,6 +33234,12 @@ plexiform layer. White matter structure of CNS that contains axons that arise predominantly in one central nervous system part and terminate in another. Tracts are generally named by their region or origin followed by their region of primary termination, e.g., mammillothalamic tract contains axons that arise from neurons in the mammillary bodies and terminate in the thalamus. (CUMBO) http://neurolex.org/wiki/Cumbo_terms + + + + FBbt:00005100 + + @@ -33233,7 +33309,7 @@ plexiform layer. fasciculus - + @@ -33337,13 +33413,19 @@ plexiform layer. DOI:10.1073/pnas.97.9.4449 Shimeld SM and Holland PW. Vertebrate innovations. PNAS (2000) http://bgee.unil.ch/ + + + + FBbt:00007692 + + organa sensuum FMA:75259 FMA:TA - + @@ -33369,7 +33451,7 @@ plexiform layer. organa sensuum Wikipedia:Sensory_system - + @@ -33429,6 +33511,12 @@ plexiform layer. FB:FBrf0089570 http://flybase.org/reports/FBrf0178740.html + + + + FBbt:00005495 + + @@ -33549,6 +33637,14 @@ plexiform layer. The mature structure of the neural tube exists when the tube has been segmented into the forebrain, midbrain, hindbrain and spinal cord regions. In addition neural crest has budded away from the epithelium GO:0021915 + + + + MESH:D054259 + + + https://github.com/biopragmatics/biomappings + @@ -33560,7 +33656,7 @@ plexiform layer. tubus neuralis Wikipedia:Neural_tube - + @@ -33603,6 +33699,12 @@ plexiform layer. FMA:62955 http://orcid.org/0000-0001-9114-8737 + + + + FBbt:10000000 + + @@ -33737,7 +33839,7 @@ plexiform layer. textus muscularis nonstriatus FMA:14070 FMA:TA - + @@ -33756,7 +33858,7 @@ plexiform layer. textus muscularis levis; textus muscularis nonstriatus Wikipedia:Smooth_muscle_tissue - + @@ -33787,7 +33889,7 @@ plexiform layer. - + Simple squamous epithelium of mesodermal origin which lines serous membranes. Examples: mesothelium of pleura, mesothelium of peritoneum[FMA]. Wikipedia: The mesothelium is a membrane that forms the lining of several body cavities: the pleura (thoracal cavity), peritoneum (abdominal cavity including the mesentery) and pericardium (heart sac). Mesothelial tissue also surrounds the male internal reproductive organs (the tunica vaginalis testis) and covers the internal reproductive organs of women (the tunica serosa uteri). AEO:0000111 BTO:0002422 @@ -33812,14 +33914,14 @@ plexiform layer. mesothelium http://upload.wikimedia.org/wikipedia/commons/2/25/Mesothelium_peritoneal_wash_high_mag.jpg - + - + FMA @@ -34159,7 +34261,7 @@ plexiform layer. facia/facies Wikipedia:Face - + @@ -34192,7 +34294,7 @@ plexiform layer. - + A tube extending from the mouth to the anus. @@ -34213,6 +34315,7 @@ plexiform layer. FBbt:00003125 FMA:45615 MA:0000917 + MESH:D041981 NCIT:C34082 TAO:0000112 TGMA:0001819 @@ -34234,14 +34337,14 @@ plexiform layer. digestive tract - + - + NCBIBook:NBK10107 @@ -34294,6 +34397,19 @@ plexiform layer. we place the MA and EMAPA class here, although the intent is probably a smaller region. See https://github.com/obophenotype/uberon/issues/509 MA + + + + FBbt:00003125 + + + + + + MESH:D041981 + + https://github.com/biopragmatics/biomappings + @@ -34321,7 +34437,7 @@ plexiform layer. - + The ciliary muscle is a ring of smooth muscle in the middle layer of the eye that controls the eye's accommodation for viewing objects at varying distances and regulates the flow of aqueous humour through Schlemm's canal. [WP,unvetted]. BTO:0000654 @@ -34344,7 +34460,7 @@ plexiform layer. ciliary muscle http://upload.wikimedia.org/wikipedia/commons/2/28/Gray872.png - + @@ -34363,7 +34479,7 @@ plexiform layer. - + FMA @@ -34401,7 +34517,7 @@ plexiform layer. musculus ciliaris Wikipedia:Ciliary_muscle - + @@ -34504,7 +34620,7 @@ plexiform layer. - + @@ -34556,14 +34672,14 @@ plexiform layer. eyelid https://upload.wikimedia.org/wikipedia/commons/8/84/Eye_makeup.jpg - + - + multiple @@ -34703,7 +34819,7 @@ plexiform layer. camera anterior bulbi oculi Wikipedia:Anterior_chamber_of_eyeball - + @@ -34836,7 +34952,7 @@ plexiform layer. tunica vasculosa bulbi Wikipedia:Uvea - + @@ -34858,7 +34974,7 @@ plexiform layer. - + @@ -34901,14 +35017,14 @@ plexiform layer. iris - + - + XAO @@ -34980,7 +35096,7 @@ plexiform layer. - + @@ -35032,14 +35148,14 @@ plexiform layer. corneal epithelium http://upload.wikimedia.org/wikipedia/commons/6/66/Gray871.png - + - + ISBN:0781772214 @@ -35089,7 +35205,7 @@ plexiform layer. epithelium anterius corneae FMA:58263 FMA:TA - + @@ -35102,7 +35218,7 @@ plexiform layer. e. anterius corneae Wikipedia:Corneal_epithelium - + @@ -35135,16 +35251,16 @@ plexiform layer. - - + + - - + + @@ -35186,44 +35302,44 @@ plexiform layer. sclera http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg - + - + - + - + - + FMA - + ZFA - + ISBN:0781772214 - + cjm ISBN:0781772214 Wikipedia @@ -35283,7 +35399,7 @@ plexiform layer. - + @@ -35322,14 +35438,14 @@ plexiform layer. ciliary body http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg - + - + ISBN:0781772214 @@ -35368,7 +35484,7 @@ plexiform layer. corpus ciliare Wikipedia:Ciliary_body - + @@ -35377,14 +35493,14 @@ plexiform layer. - + - + @@ -35447,24 +35563,24 @@ plexiform layer. optic choroid http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg - + - + - + MA - + Wikipedia @@ -35532,7 +35648,7 @@ plexiform layer. choroidea Wikipedia:Choroid - + @@ -35564,7 +35680,7 @@ plexiform layer. - + @@ -35613,14 +35729,14 @@ plexiform layer. substantia propria of cornea http://upload.wikimedia.org/wikipedia/commons/6/66/Gray871.png - + - + cjm ISBN:0781772214 Wikipedia @@ -35676,7 +35792,7 @@ plexiform layer. substantia propria corneae FMA:58306 FMA:TA - + @@ -35697,9 +35813,9 @@ plexiform layer. - - - + + + A double layer covering the ciliary body that produces aqueous humor. BTO:0001770 @@ -35719,15 +35835,15 @@ plexiform layer. ciliary epithelium - + - + - + @@ -35740,19 +35856,19 @@ plexiform layer. - + MA - + MP - + Wikipedia @@ -35875,7 +35991,7 @@ plexiform layer. - + @@ -35936,14 +36052,14 @@ plexiform layer. pigmented layer of retina http://upload.wikimedia.org/wikipedia/commons/5/55/Gray881.png - + - + Wikipedia @@ -36006,7 +36122,7 @@ plexiform layer. stratum pigmentosum retinae FMA:58627 FMA:TA - + @@ -36019,7 +36135,7 @@ plexiform layer. p. pigmentosa retinae Wikipedia:Retinal_pigment_epithelium - + @@ -36032,7 +36148,7 @@ plexiform layer. stratum pigmentosa retinae Wikipedia:Retinal_pigment_epithelium - + @@ -36047,7 +36163,7 @@ plexiform layer. - + @@ -36081,14 +36197,14 @@ plexiform layer. photoreceptor layer of retina http://upload.wikimedia.org/wikipedia/commons/5/55/Gray881.png - + - + ZFA @@ -36132,7 +36248,7 @@ plexiform layer. stratum segmentorum externorum et internorum retinae FMA:58680 FMA:TA - + @@ -36226,7 +36342,7 @@ plexiform layer. stratum limitans externum retinae FMA:58683 FMA:TA - + @@ -36261,7 +36377,7 @@ plexiform layer. - + @@ -36308,14 +36424,14 @@ plexiform layer. outer nuclear layer of retina - + - + soma ZFA @@ -36353,7 +36469,7 @@ plexiform layer. stratum nucleare externum retinae FMA:58684 FMA:TA - + @@ -36485,7 +36601,7 @@ plexiform layer. stratum plexiforme externum retinae FMA:58685 FMA:TA - + @@ -36632,7 +36748,7 @@ plexiform layer. stratum nucleare internum retinae FMA:58686 FMA:TA - + @@ -36653,7 +36769,7 @@ plexiform layer. - + @@ -36712,7 +36828,7 @@ plexiform layer. ganglionic layer of retina http://upload.wikimedia.org/wikipedia/commons/5/55/Gray881.png - + @@ -36725,7 +36841,7 @@ plexiform layer. - + FMA @@ -36792,7 +36908,7 @@ plexiform layer. stratum ganglionicum retinae Wikipedia:Ganglion_cell_layer - + @@ -36801,7 +36917,7 @@ plexiform layer. - + @@ -36857,14 +36973,14 @@ plexiform layer. nerve fiber layer of retina - + - + FMA @@ -36902,7 +37018,7 @@ plexiform layer. stratum neurofibrarum retinae FMA:58688 FMA:TA - + @@ -36928,7 +37044,7 @@ plexiform layer. stratum neurofibrum retinae Wikipedia:Nerve_fiber_layer - + @@ -37038,7 +37154,7 @@ plexiform layer. stratum limitans internum retinae FMA:58689 FMA:TA - + @@ -37232,7 +37348,7 @@ plexiform layer. stratum plexiforme internum retinae Wikipedia:Inner_plexiform_layer - + @@ -37242,7 +37358,7 @@ plexiform layer. - + @@ -37278,14 +37394,14 @@ plexiform layer. aqueous humor of eyeball http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg - + - + FMA def states A and P located_in in EHDAA2 VHOG @@ -37340,7 +37456,7 @@ plexiform layer. humor aquosus FMA:58819 FMA:TA - + @@ -37376,6 +37492,7 @@ plexiform layer. EV:0100344 FMA:58822 MA:0001286 + MESH:D014822 NCIT:C13323 UMLS:C0229096 VHOG:0000795 @@ -37409,6 +37526,13 @@ plexiform layer. portion of vitreous humor FMA:67388 + + + + MESH:D014822 + + https://github.com/biopragmatics/biomappings + @@ -37421,7 +37545,7 @@ plexiform layer. humor vitreus FMA:58822 FMA:TA - + @@ -37467,7 +37591,7 @@ plexiform layer. - + @@ -37491,7 +37615,7 @@ plexiform layer. vitreous body http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg - + @@ -37504,7 +37628,7 @@ plexiform layer. - + neural ectoderm of optic cup ISBN:0781772214 @@ -37600,7 +37724,7 @@ plexiform layer. camera postrema bulbi oculi FMA:58848 FMA:TA - + @@ -37639,8 +37763,8 @@ plexiform layer. - - + + @@ -37673,24 +37797,24 @@ plexiform layer. anterior segment of eyeball http://upload.wikimedia.org/wikipedia/commons/b/ba/Cataract_in_human_eye.png - + - + - + FMA - + cjm @@ -37732,7 +37856,7 @@ plexiform layer. segmentum anterius bulbi oculi Wikipedia:Anterior_segment_of_eyeball - + @@ -37741,8 +37865,8 @@ plexiform layer. - - + + @@ -37772,24 +37896,24 @@ plexiform layer. posterior segment of eyeball http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg - + - + - + FMA - + cjm @@ -37816,7 +37940,7 @@ plexiform layer. segmentum posterius bulbi oculi Wikipedia:Posterior_segment_of_eyeball - + @@ -37825,9 +37949,9 @@ plexiform layer. - - - + + + @@ -37877,15 +38001,15 @@ plexiform layer. conjunctiva http://upload.wikimedia.org/wikipedia/commons/5/55/Gray883.png - + - + - + @@ -37898,19 +38022,19 @@ plexiform layer. - + cjm - + MA - + ISBN:0781772214 @@ -37946,7 +38070,7 @@ plexiform layer. tunica conjunctiva FMA:TA - + @@ -37974,7 +38098,7 @@ plexiform layer. - + The most anterior region of the brain including both the telencephalon and diencephalon. @@ -38021,14 +38145,14 @@ plexiform layer. forebrain http://upload.wikimedia.org/wikipedia/commons/5/54/EmbryonicBrain.svg - + - + definitional @@ -38104,14 +38228,14 @@ plexiform layer. - + - + The midbrain is the middle division of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes a ventral part containing the cerebral peduncles and a dorsal tectum containing the corpora quadrigemina and that surrounds the aqueduct of Sylvius connecting the third and fourth ventricles)[GO]. developmental relationships need revised @@ -38164,24 +38288,24 @@ plexiform layer. midbrain http://upload.wikimedia.org/wikipedia/commons/f/f9/Human_brain_inferior_view_description.JPG - + - + - + definitional - + Bgee:AN @@ -38267,7 +38391,7 @@ plexiform layer. mesencephalon Wikipedia:Midbrain - + @@ -38284,14 +38408,14 @@ plexiform layer. - + - + The division of the forebrain that develops from the foremost primary cerebral vesicle. @@ -38354,24 +38478,24 @@ plexiform layer. diencephalon http://upload.wikimedia.org/wikipedia/commons/5/54/EmbryonicBrain.svg - + - + - + definitional - + definitional @@ -38486,7 +38610,7 @@ plexiform layer. diencephalon Wikipedia:Diencephalon - + @@ -38643,14 +38767,14 @@ plexiform layer. bulbus FMA:62004 FMA:TA - + medulla oblonzata Wikipedia:Medulla_oblongata - + @@ -38775,14 +38899,14 @@ plexiform layer. tractus optici NeuroNames:460 - + tractus opticus Wikipedia:Optic_tract - + @@ -38809,7 +38933,7 @@ plexiform layer. - + Ventral part of the midbrain, separated from the hindbrain by the isthmus[ISBN:0471888893]. Subdivision of the midbrain lying anterior to the tectum and posterior to the substantia nigra and cerebral peduncle[FMA] The part of the midbrain extending from the substantia nigra to the cerebral aqueduct in a horizontal section of the midbrain. It forms the floor of the midbrain that surrounds the cerebral aqueduct[WP]. Together, our results reveal a shared basic organization in the tegmental domains of the diencephalon and midbrain of developing lamprey, indicating early appearance of the domain in vertebrate phylogeny.[well established][VHOG] @@ -38826,6 +38950,7 @@ plexiform layer. HBA:9002 MA:0000212 MAT:0000452 + MESH:D013681 SCTID:362392007 TAO:0000160 UMLS:C0039441 @@ -38849,14 +38974,14 @@ plexiform layer. midbrain tegmentum http://upload.wikimedia.org/wikipedia/commons/b/b6/Gray712.png - + - + ZFA @@ -38891,6 +39016,13 @@ plexiform layer. tegmentum ISBN:0471888893 + + + + MESH:D013681 + + https://github.com/biopragmatics/biomappings + @@ -38908,7 +39040,7 @@ plexiform layer. tegmentum mesencephali Wikipedia:Midbrain_tegmentum - + @@ -38921,7 +39053,7 @@ plexiform layer. tegmentum mesencephalicum NeuroNames:491 - + @@ -39035,8 +39167,8 @@ plexiform layer. - - + + @@ -39049,7 +39181,7 @@ plexiform layer. - + @@ -39108,34 +39240,34 @@ plexiform layer. blood vessel http://upload.wikimedia.org/wikipedia/commons/2/29/Circulatory_System_en.svg - + - + - + - + AEO - + EHDAA2 - + GO:0072360 @@ -39208,7 +39340,7 @@ plexiform layer. vas sanguineum Wikipedia:Blood_vessel - + @@ -39304,7 +39436,7 @@ plexiform layer. epithelium posterius corneae Wikipedia:Corneal_endothelium - + @@ -39448,6 +39580,14 @@ plexiform layer. EMAPA:37596 MA:th + + + + MESH:D066128 + + + https://github.com/biopragmatics/biomappings + @@ -39472,7 +39612,7 @@ plexiform layer. substantia grisea FMA:67242 FMA:TA - + @@ -39484,7 +39624,7 @@ plexiform layer. grisea - + @@ -39494,7 +39634,7 @@ plexiform layer. - + @@ -39507,7 +39647,7 @@ plexiform layer. - + The most posterior of the three principal regions of the brain. In mammals and birds the hindbrain is divided into a rostral metencephalon and a caudal myelencephalon. In zebrafish, with the exception of the cerebellum, the ventral remainder of the metencephalon can be separated only arbitrarily from the more caudal myelencephalic portion of the medulla oblongata (From: Neuroanatomy of the Zebrafish Brain)[ZFA]. Organ component of neuraxis that has as its parts the pons, cerebellum and medulla oblongata[FMA]. @@ -39558,25 +39698,25 @@ plexiform layer. hindbrain http://upload.wikimedia.org/wikipedia/commons/5/54/EmbryonicBrain.svg - + - + - + modified-source-relation ABA - + Bgee:AN @@ -39828,6 +39968,12 @@ plexiform layer. in FMA embryo is_a embryonic structure FMA + + + + FBbt:00004208 + + @@ -40005,6 +40151,7 @@ plexiform layer. FMA:71221 MA:0002986 MAT:0000148 + MESH:D013131 MIAA:0000148 TAO:0000317 VHOG:0000317 @@ -40080,6 +40227,13 @@ plexiform layer. EMAPA:37721 MA:th + + + + MESH:D013131 + + https://github.com/biopragmatics/biomappings + @@ -40395,7 +40549,7 @@ plexiform layer. - + Vasculature that is part of the eye region. not part of the eye in ZFA. Note this changed to a blood vessel in ZFA @@ -40418,14 +40572,14 @@ plexiform layer. https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Blood_Vasculature.glb https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Blood_Vasculature.glb - + - + ISBN:0781772214 @@ -40484,7 +40638,7 @@ plexiform layer. - + @@ -40518,14 +40672,14 @@ plexiform layer. musculoskeletal system - + - + check ctenophore @@ -40639,7 +40793,7 @@ plexiform layer. cavitas thoracis Wikipedia:Thoracic_cavity - + @@ -40663,15 +40817,15 @@ plexiform layer. - + - - + + Part of the central nervous system located in the vertebral canal continuous with and caudal to the brain; demarcated from brain by plane of foramen magnum. It is composed of an inner core of gray matter in which nerve cells predominate, and an outer layer of white matter in which myelinated nerve fibers predominate, and surrounds the central canal. (CUMBO). TODO - add superclass to unify with VNC? @@ -40730,34 +40884,34 @@ plexiform layer. https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Spinal_Cord.glb https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Spinal_Cord.glb - + - + - + - + ZFA - + definitional - + definitional @@ -40829,14 +40983,14 @@ plexiform layer. fissura cerebro-cerebellaris NeuroNames:22 - + fissura cerebrocerebellaris NeuroNames:22 - + @@ -40844,7 +40998,7 @@ plexiform layer. medulla spinalis BTO:0001279 Wikipedia:Spinal_cord - + @@ -41008,7 +41162,7 @@ plexiform layer. truncus encephali Wikipedia:Brainstem - + @@ -41021,35 +41175,35 @@ plexiform layer. lamella pallidi incompleta NeuroNames:236 - + lamina medullaris accessoria NeuroNames:236 - + lamina medullaris incompleta pallidi NeuroNames:236 - + lamina pallidi incompleta NeuroNames:236 - + truncus encephalicus BTO:0000146 - + @@ -41143,6 +41297,14 @@ plexiform layer. NIF https://github.com/SciCrunch/NIF-Ontology/issues/83 + + + + MESH:D066127 + + + https://github.com/biopragmatics/biomappings + @@ -41184,7 +41346,7 @@ plexiform layer. substantia alba Wikipedia:White_matter - + @@ -41199,7 +41361,7 @@ plexiform layer. - + @@ -41240,14 +41402,14 @@ plexiform layer. EDITOR_NOTE check the FMA placement here; ncit placement of body cavity here probably not correct coelemic cavity lumen - + - + definitional @@ -41280,6 +41442,12 @@ plexiform layer. body cavity BTO:0001707 + + + + FBbt:00005060 + + @@ -41355,9 +41523,9 @@ plexiform layer. - - - + + + @@ -41412,15 +41580,15 @@ plexiform layer. notochord http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + - + - + @@ -41439,19 +41607,19 @@ plexiform layer. - + http://tolweb.org/Chordata/2499 - + ZFA - + EHDAA2 @@ -41526,7 +41694,7 @@ plexiform layer. notochorda Wikipedia:Notochord - + @@ -41536,8 +41704,8 @@ plexiform layer. - - + + Somites are spheres of epithelial cells that form sequentially along the anterior-posterior axis of the embryo through mesenchymal to epithelial transition of the presomitic mesoderm. EDITOR_NOTE currently classified as an epithelial vesicle, consistent with EHDAA2 and https://github.com/obophenotype/uberon/wiki/The-neural-crest. Consider making 'somitic mesoderm' a separate term and correlate with regionalization processes. Consider moving ZFA term to 'trunk somite' as it is part of the trunk @@ -41583,11 +41751,11 @@ plexiform layer. somite http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + - + @@ -41600,13 +41768,13 @@ plexiform layer. - + GOTAX:0000352 - + ZFA @@ -41709,7 +41877,7 @@ plexiform layer. somitus Wikipedia:Somite - + @@ -41719,12 +41887,12 @@ plexiform layer. - - - - - - + + + + + + A specialized region of ectoderm found between the neural ectoderm (neural plate) and non-neural ectoderm and composed of highly migratory pluripotent cells that delaminate in early embryonic development from the dorsal neural tube and give rise to an astounding variety of differentiated cell types[MP]. EDITOR_NOTE consider including subclasses for pre- and post- migratory (e.g. sheets/paths/streams). @@ -41764,66 +41932,66 @@ plexiform layer. http://upload.wikimedia.org/wikipedia/commons/5/5f/Gray644.png https://upload.wikimedia.org/wikipedia/commons/8/8f/Neural_Crest.png - + - + - + - + - + - + - + XAO https://github.com/obophenotype/uberon/wiki/The-neural-crest - + Hall and others restrict NC to vertebrates but we opt for a less restrictive constraint to avoid inconsistencies when areas such as P1 area of pallium in hagfishes inherit cell lineage from telecephalon-contributing NC cells ISBN:0073040584 - + BTO - + PMID:11523831 - + pre migratory https://github.com/obophenotype/uberon/wiki/The-neural-crest - + PMID:11523831 @@ -41891,7 +42059,7 @@ plexiform layer. crista neuralis Wikipedia:Neural_crest - + @@ -41964,6 +42132,12 @@ plexiform layer. DOI:10.1046/j.1469-7580.2001.19910133.x Graham A. The development and evolution of the pharyngeal arches. J Anat (2001) http://bgee.unil.ch/ + + + + FBbt:00001057 + + @@ -41975,7 +42149,7 @@ plexiform layer. epithelium tubi neuralis; neuroectoderma Wikipedia:Neuroectoderm - + @@ -42206,14 +42380,14 @@ plexiform layer. - + - + Anatomical system that is involved in the production of hematopoietic cells. @@ -42258,24 +42432,24 @@ plexiform layer. hematopoietic system - + - + - + FMA - + definitional @@ -42340,8 +42514,8 @@ plexiform layer. - - + + @@ -42367,11 +42541,11 @@ plexiform layer. iris epithelium - + - + @@ -42384,13 +42558,13 @@ plexiform layer. - + MA - + MP @@ -42423,7 +42597,7 @@ plexiform layer. epithelium pigmentosum iridis FMA:58517 FMA:TA - + @@ -42519,7 +42693,7 @@ plexiform layer. epiblastus Wikipedia:Epiblast - + @@ -42540,7 +42714,7 @@ plexiform layer. - + Ectodermal placode that develops in the head into a part of the sensory nervous system. With a few exceptions (lens, adenohypophyseal), cranial placodes are neurogenic. Do not merge with neurogenic placode Comparisons of developmental gene expression suggest that the anterior ectoderm in amphioxus may be homologous to the vertebrate olfactory placode, the only vertebrate placode with primary, not secondary, neurons @@ -42560,7 +42734,7 @@ plexiform layer. cranial placode - + @@ -42573,7 +42747,7 @@ plexiform layer. - + PMID:11523831 PMID:22512454 @@ -42778,7 +42952,7 @@ plexiform layer. - + @@ -42791,7 +42965,7 @@ plexiform layer. - + The part of the brain that is the morphological boundary between the midbrain and hindbrain and that is the location of an organizing center which patterns the midbrain and hindbrain primordia of the neural plate. consider adding class for organizer. Consider adding separate class for isthmus as a structure Lampreys also have an MHB [midbrain hindbrain boundary], expressing a similar repertoire of regulatory gene cognates as in gnathostomes.[well established][VHOG] @@ -42821,11 +42995,11 @@ plexiform layer. midbrain-hindbrain boundary - + - + @@ -42839,13 +43013,13 @@ plexiform layer. - + ZFA - + ZFA @@ -43010,7 +43184,7 @@ plexiform layer. - + Unsegmented field of paraxial mesoderm present posterior to the most recently formed somite pair, from which somites will form. Unsegmented field of paraxial mesoderm present posterior to the most recently formed somite pair, from which somites will form. Kimmel et al, 1995.[TAO] It is reasonable to assume that the proximate invertebrate ancestor of the vertebrates had an amphioxus-like tail bud in its larval stage. This archetypal tail bud would have (...) (3) lacked any component of mesenchyme cells, (4) budded off new mesodermal segments directly, without any intervening zone of presomitic mesoderm (...). Then, early in vertebrate evolution, epithelium-to-mesenchyme interconversions (and the gene networks for effecting them) became prominent features of development. (...) In any case, conspicuous mesenchymal components tended to be added to the vertebrate tail bud itself. In addition, a mesenchymatous presomitic mesoderm (not a part of the tail bud proper) came to intervene between the tail bud and the forming somites.[well established][VHOG] @@ -43035,14 +43209,14 @@ plexiform layer. presomitic mesoderm - + - + Bgee:AN @@ -43284,7 +43458,7 @@ plexiform layer. - + @@ -43322,7 +43496,7 @@ plexiform layer. eye primordium - + @@ -43335,7 +43509,7 @@ plexiform layer. - + PMID:16496288 XAO @@ -43391,8 +43565,8 @@ plexiform layer. - - + + @@ -43421,24 +43595,24 @@ plexiform layer. optic cup - + - + - + ZFA - + ZFA @@ -43503,7 +43677,7 @@ plexiform layer. - + @@ -43544,7 +43718,7 @@ plexiform layer. lens placode http://upload.wikimedia.org/wikipedia/commons/2/2f/Gray864.png - + @@ -43557,7 +43731,7 @@ plexiform layer. - + ZFA @@ -43610,7 +43784,7 @@ plexiform layer. placoda lentis Wikipedia:Lens_placode - + @@ -43621,9 +43795,9 @@ plexiform layer. - - - + + + A region of embryonic ectodermal cells that lie directly above the notochord. During neurulation, they change shape and produce an infolding of the neural plate (the neural fold) that then seals to form the neural tube[XAO]. The earliest recognizable dorsal ectodermal primordium of the central nervous system present near the end of gastrulation before infolding to form the neural keel; consists of a thickened pseudostratified epithelium[ZFA]. The earliest recognizable dorsal ectodermal primordium of the central nervous system present near the end of gastrulation before infolding to form the neural keel; consists of a thickened pseudostratified epithelium. Kimmel et al, 1995.[TAO] (...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord that is located dorsal to the notochord (...).[well established][VHOG] @@ -43655,34 +43829,34 @@ plexiform layer. neural plate https://upload.wikimedia.org/wikipedia/commons/8/8f/Neural_Crest.png - + - + - + - + GOTAX:0000352 - + Wikipedia - + Bgee:AN @@ -43713,6 +43887,14 @@ plexiform layer. ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.28 http://bgee.unil.ch/ + + + + MESH:D054258 + + + https://github.com/biopragmatics/biomappings + @@ -43724,7 +43906,7 @@ plexiform layer. lamina neuralis Wikipedia:Neural_plate - + @@ -43793,7 +43975,7 @@ plexiform layer. - + The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube[GO]. Mesoderm lateral to the neural tube and notochord that is divided into cranial and post-cranial portions. The trunk portions further segment into somites.[AAO] Presently, Cephalochordata, Urochordata, and Vertebrata are placed as subphyla of the phylum Chordata, in which the overall organization of embryonic tissues (dorsal hollow nerve cord, ventral digestive tract, axial notochord, and bilateral paraxial mesoderm) is largely conserved. In contrast, the echinoderms and hemichordates are sister groups of the chordates and they lack the notochord and paraxial mesoderm. Thus, the basic mesodermal organization of vertebrates must have appeared first in the common ancestor of the chordates.[well established][VHOG] @@ -43822,7 +44004,7 @@ plexiform layer. paraxial mesoderm http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + @@ -43835,7 +44017,7 @@ plexiform layer. - + Bgee:AN @@ -43895,7 +44077,7 @@ plexiform layer. mesoderma paraxiale Wikipedia:Paraxial_mesoderm - + @@ -43947,7 +44129,7 @@ plexiform layer. - + @@ -43991,7 +44173,7 @@ plexiform layer. lateral plate mesoderm http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + @@ -44004,7 +44186,7 @@ plexiform layer. - + EHDAA2 VHOG @@ -44079,7 +44261,7 @@ plexiform layer. mesoderma laminae lateralis Wikipedia:Lateral_plate_mesoderm - + @@ -44088,15 +44270,15 @@ plexiform layer. - - + + - + Bilateral groups of cells consisting of three rows: one row of endocardial precursors medially and two rows of myocardical precursors laterally. The two populations fuse at the midline to form the heart rudiment or cone. should probably be merged with heart rudiment. Bilateral groups of cells consisting of three rows: one row of endocardial precursors medially and two rows of myocardical precursors laterally. The two populations fuse at the midline between 21 and 26 somites to form the heart rudiment or cone. Stainier 2001.[TAO] @@ -44116,15 +44298,15 @@ plexiform layer. heart primordium - + - + - + @@ -44137,19 +44319,19 @@ plexiform layer. - + ZFA - + ZFA - + XAO @@ -44204,8 +44386,8 @@ plexiform layer. - - + + Ventral somitic compartment that is a precursor of the axial skeleton[XAO]. Sclerotomes eventually differentiate into the vertebrae and most of the skull. The caudal (posterior) half of one sclerotome fuses with the rostral (anterior) half of the adjacent one to form each vertebra. From their initial location within the somite, the sclerotome cells migrate medially towards the notochord. These cells meet the sclerotome cells from the other side to form the vertebral body. From this vertebral body, sclerotome cells move dorsally and surround the developing spinal cord, forming the vertebral arch[WP]. Skeletogenic portion of somites.[AAO] The vertebrate sclerotome has no equivalent in amphioxus and is a novelty linked with the evolution of the axial skeleton.[well established][VHOG] @@ -44233,11 +44415,11 @@ plexiform layer. sclerotome http://upload.wikimedia.org/wikipedia/commons/9/96/Gray65.png - + - + @@ -44256,13 +44438,13 @@ plexiform layer. - + VHOG:0000680 - + ZFA @@ -44302,7 +44484,9 @@ plexiform layer. BTO:0006255 - https://orcid.org/0000-0003-4423-4370 + + + https://github.com/biopragmatics/biomappings @@ -44322,7 +44506,7 @@ plexiform layer. sclerotomus Wikipedia:Sclerotome - + @@ -44420,7 +44604,7 @@ plexiform layer. pedunculus opticus Wikipedia:Optic_stalk - + @@ -44520,7 +44704,7 @@ plexiform layer. crista neuralis cranialis Wikipedia:Cranial_neural_crest - + @@ -44660,7 +44844,7 @@ plexiform layer. mesenchyma Wikipedia:Mesenchyme - + @@ -44686,7 +44870,7 @@ plexiform layer. - + Mesenchyme that is part of a developing camera-type eye. TODO - change mesenchyme relationships to precursor_of EHDAA2:0000485 @@ -44698,14 +44882,14 @@ plexiform layer. UBERON:0003314 eye mesenchyme - + - + EHDAA2 @@ -45563,7 +45747,7 @@ plexiform layer. - + The part of the coelom in the embryo between the somatopleuric and splanchnopleuric mesoderm; the principal body cavities of the trunk (thoracic, abdominal, and pelvic) arise from this embryonic part of the coelom. consider merging with coelom. TODO - add spatial relationships to halves of LPM. Note the OG places XAO and ZFA coelem terms here. editor note: TODO check ZFA, which appears to be a structure present in adults (...) I regard it unlikely that coeloms of all bilaterian animals are comparable and evolved very early. Considering all these questions, few convincing characters concerning the evolution of body cavities remain to be named. (...) A segmental coelom appears to have evolved at least two times, in Annelida and in Myomerata (Acrania and Craniota).[well established][VHOG] @@ -45579,14 +45763,14 @@ plexiform layer. intraembryonic coelom - + - + Wikipedia @@ -45691,7 +45875,7 @@ plexiform layer. - + The part of the retina that contains neurons and photoreceptor cells[GO]. (...) an essentially similar sequence of events occurs during the embryonic development of the vertebrate eye. The eye initially develops as a single median evagination of the diencephalon that soon bifurcates to form the paired optic vesicles. As each optic vesicle grows towards the body surface, its proximal part narrows as the optic stalk, and its distal part invaginates to form a two-layered optic cup. (...) The outer layer of the optic cup becomes the pigment layer of the retina, whereas the inner layer differentiates into the photoreceptive cells and neuronal layers of the retina.[well established][VHOG] @@ -45723,14 +45907,14 @@ plexiform layer. retinal neural layer - + - + Bgee:AN @@ -45786,7 +45970,7 @@ plexiform layer. stratum nervosum retinae FMA:58628 FMA:TA - + @@ -45830,6 +46014,12 @@ plexiform layer. GO:0060562 PMID:12526790 + + + + FBbt:00007474 + + @@ -45988,7 +46178,7 @@ plexiform layer. - + The layer of undifferentiated, proliferating cells that line the neural tube lumen that is the immediate transformation of the germinal neuroepithelium. consider merging with 'ventricular zone'; note that the MA class probably does not belong here, as this is an embryonic structure The layer of undifferentiated, proliferating cells that line the neural tube lumen @@ -46006,7 +46196,7 @@ plexiform layer. neural tube ventricular layer - + @@ -46019,7 +46209,7 @@ plexiform layer. - + NCBIBook:NBK10047 @@ -46079,7 +46269,7 @@ plexiform layer. - + @@ -46103,7 +46293,7 @@ plexiform layer. neural tube mantle layer - + @@ -46116,7 +46306,7 @@ plexiform layer. - + by division NCBIBook:NBK10047 @@ -46153,7 +46343,7 @@ plexiform layer. - + @@ -46170,14 +46360,14 @@ plexiform layer. neural tube marginal layer - + - + forms from axons @@ -46452,9 +46642,9 @@ plexiform layer. - - - + + + @@ -46487,34 +46677,34 @@ plexiform layer. optic vesicle http://upload.wikimedia.org/wikipedia/commons/e/e0/Gray863.png - + - + - + - + ZFA - + GO-def - + ZFA @@ -46630,8 +46820,8 @@ plexiform layer. - - + + A specific region of the lateral mesoderm that will form the primary beating heart tube. In mammals the primary heart field gives rise to the left ventricle. this term denotes the primary heart field; GO:0003128 denotes the superclass of primary and secondary: specific region of the lateral mesoderm into the area which will form the primary beating heart tube[GO:0003138] XAO:0004185 @@ -46644,24 +46834,24 @@ plexiform layer. UBERON:0004140 primary heart field - + - + - + GO:0003128 - + https://orcid.org/0000-0003-3308-6245 @@ -46720,7 +46910,7 @@ plexiform layer. - + An epithelial tube that will give rise to the mature heart. the paired, longitudinal, endothelial-lined channels formed from the cardiogenic mesoderm in embryonic development; angiogenic cell clusters (aka angioblastic cords) located in a horse-shoe shape configuration in the cardiogenic plate coalesce to form the right and left endocardial heart tubes which then fuse in cephalo-caudal direction to form a single primitive heart tube. AAO:0010411 @@ -46740,14 +46930,14 @@ plexiform layer. heart tube - + - + ZFA-modified @@ -46828,7 +47018,7 @@ plexiform layer. - + @@ -46844,14 +47034,14 @@ plexiform layer. eye muscle - + - + MA @@ -47055,7 +47245,7 @@ plexiform layer. - + A transparent homogeneous acellular layer found between the substantia propria and the endothelial layer of the cornea[MP]. Acellular anatomical structure composed of collagen, Descemet's membrane is secreted as a basement membrane of the corneal endothelium. Located between the stroma and the corneal endothelium, it is approximately 0.15 micrometer thick at 6 months post-fertilization.[ZFIN] @@ -47085,14 +47275,14 @@ plexiform layer. Descemet's membrane https://github.com/obophenotype/uberon/issues/15 - + - + Cline et al @@ -47142,7 +47332,7 @@ plexiform layer. lamina limitans posterior corneae FMA:58309 FMA:TA - + @@ -47292,14 +47482,14 @@ plexiform layer. lamina limitans anterior corneae FMA:58273 FMA:TA - + Reichert's membrane http://sourceforge.net/tracker/?func=detail&aid=2956371&group_id=76834&atid=974957 - + @@ -47544,6 +47734,7 @@ plexiform layer. An endothelium that lines the blood vasculature. Other endothelia may line lymph vessels, the heart. + BTO:0000766 CALOHA:TS-2155 EMAPA:35176 @@ -47554,6 +47745,7 @@ plexiform layer. ZFA:0005257 uberon UBERON:0004638 + blood vessel endothelium @@ -47804,6 +47996,12 @@ plexiform layer. We explicitly merge the NCITA terms here NCIT + + + + FBbt:00005317 + + @@ -47877,7 +48075,7 @@ plexiform layer. - + Organ consisting of skeletal tissue. Encompasses whole bones, fused bones, cartilaginious elements, teeth, dermal denticles. Organ entity that is typically involved in mechanical support and may have different skeletal tissue compositions at different stages.[VSAO] Organ entity that may have different tissue compositions at different stages and is typically involved in mechanical support.[TAO] @@ -47893,14 +48091,14 @@ plexiform layer. skeletal element - + - + VSAO @@ -47945,7 +48143,7 @@ plexiform layer. - + @@ -47984,14 +48182,14 @@ plexiform layer. UBERON:0004770 articular system - + - + FMA @@ -48246,6 +48444,12 @@ plexiform layer. Anatomical structure that connects two or more adjacent skeletal elements or hardened body parts. http://orcid.org/0000-0002-6601-2165 + + + + FBbt:00005811 + + @@ -48298,6 +48502,12 @@ plexiform layer. A proximal-distal subdivision of the digestive tract. http://orcid.org/0000-0002-6601-2165 + + + + FBbt:00100315 + + @@ -48649,6 +48859,12 @@ plexiform layer. CARO FMA + + + + FBbt:00007060 + + @@ -48900,7 +49116,7 @@ plexiform layer. - + Portion of primordial embryonic connective tissue of the developing head, consisting of mesenchymal cells supported in interlaminar jelly, that derive mostly from the mesoderm and contribute to head connective tissue, bone and musculature in conjunction with cranial neural crest cells. Mesoderm that will give rise, along with cranial neural crest cells, to connective tissue, bone and musculature in the head. (Source: BioGlossary, www.Biology-Text.com)[TAO] EFO:0003492 @@ -48922,14 +49138,14 @@ plexiform layer. head mesenchyme - + - + EHDAA2 @@ -48996,7 +49212,7 @@ plexiform layer. - + Mesenchyme that is part of a developing trunk. EFO:0003485 EHDAA2:0002092 @@ -49012,14 +49228,14 @@ plexiform layer. trunk mesenchyme - + - + EHDAA2 @@ -49042,7 +49258,7 @@ plexiform layer. - + The posterior part of the developing vertebrate hindbrain or the corresponding part of the adult brain composed of the medulla oblongata and a portion of the fourth ventricle; as well as the glossopharyngeal nerve (CN IX), vagus nerve (CN X), accessory nerve (CN XI), hypoglossal nerve (CN XII), and a portion of the vestibulocochlear nerve (CN VIII).[BTO,WP]. The posterior of the two brain vesicles formed by specialization of the rhombencephalon in the developing embryo, it comprises the medulla oblongata. [TFD][VHOG] @@ -49067,14 +49283,14 @@ plexiform layer. myelencephalon http://upload.wikimedia.org/wikipedia/commons/5/54/EmbryonicBrain.svg - + - + definitional @@ -49104,6 +49320,14 @@ plexiform layer. ISBN:978-0878932504 Gilbert SF, Developmental Biology (2006) p.381-382, ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.500 http://bgee.unil.ch/ + + + + MESH:D054024 + + + https://github.com/biopragmatics/biomappings + @@ -49209,6 +49433,12 @@ plexiform layer. An array of photoreceptors and any supporting cells found in an eye. https://orcid.org/0000-0002-6601-2165 + + + + FBbt:00004200 + + @@ -49272,6 +49502,12 @@ plexiform layer. developing anatomical structure + + + + FBbt:00007006 + + @@ -49601,7 +49837,7 @@ plexiform layer. - + Portion of tissue that is part of the eye and gives rise to the mature, fully layered cornea. TAO:0002188 ZFA:0001688 @@ -49609,7 +49845,7 @@ plexiform layer. UBERON:0005427 corneal primordium - + @@ -49628,7 +49864,7 @@ plexiform layer. - + ZFA @@ -49651,7 +49887,7 @@ plexiform layer. - + Multi-tissue structure that arises from the heart rudiment and will become the heart tube. BTO:0006179 EHDAA2:0001512 @@ -49670,14 +49906,14 @@ plexiform layer. primitive heart tube - + - + ZFA @@ -49690,7 +49926,9 @@ plexiform layer. BTO:0006179 - https://orcid.org/0000-0003-4423-4370 + + + https://github.com/biopragmatics/biomappings @@ -49870,7 +50108,7 @@ plexiform layer. membrana basalis Wikipedia:Basement_membrane - + @@ -49886,7 +50124,7 @@ plexiform layer. - + A delimited region of dense mesenchyme within looser mesenchyme. AEO:0000148 EHDAA2_RETIRED:0003148 @@ -49896,7 +50134,7 @@ plexiform layer. UBERON:0005856 developing mesenchymal condensation - + @@ -49915,7 +50153,7 @@ plexiform layer. - + AEO-modified-relation @@ -49972,9 +50210,9 @@ plexiform layer. - - - + + + A serous sac which is the aggregate of the conjunctiva plus the conjunctival space. EMAPA:18233 FMA:20291 @@ -49985,15 +50223,15 @@ plexiform layer. UBERON:0005908 conjunctival sac - + - + - + @@ -50006,19 +50244,19 @@ plexiform layer. - + FMA - + HPO:pr - + MA @@ -50111,7 +50349,7 @@ plexiform layer. skeleton axiale Wikipedia:Axial_skeleton - + @@ -50174,7 +50412,7 @@ plexiform layer. neurofibra FMA:5914 FMA:TA - + @@ -50194,7 +50432,7 @@ plexiform layer. neurofibra Wikipedia:Nerve_fiber - + @@ -50273,7 +50511,7 @@ plexiform layer. - + @@ -50296,14 +50534,14 @@ plexiform layer. future diencephalon - + - + EHDAA2 @@ -50486,7 +50724,7 @@ plexiform layer. - + @@ -50510,14 +50748,14 @@ plexiform layer. future spinal cord - + - + EHDAA2 @@ -50554,7 +50792,7 @@ plexiform layer. - + The notochordal plate is the dorsal part of the notochordal process when the ventral portion breaks down. It is continuous laterally with the endoderm that composes the roof of the primitive foregut and is in contact dorsally with the neural tube. The folding off of the notochordal plate gives rise to the notochord. TODO - check ordering; awaiting confirmation from JB The notochordal plate is the dorsal part of the notochordal process when the ventral portion breaks down. It is continuous laterally with the endoderm that composes the roof of the primitive foregut and is in contact dorsally with the neural tube. The folding off of the notochordal plate gives rise to the notochord. [Carson_JL, Dehart_DB, Developmental_Dynamics_(1994)_201:_260-278, Gesteland_K_and_Schoenwolf_GC, Inagaki_T, Morphogenesis_of_the_murine_node_and_notochordal_plate, The_prechordal_plate, Vrablic_T, see_Mueller_F_and_O'Rahilly_R, the_rostral_end_of_the_notochord_and_nearby_median_features_in_staged_human_embryos._Cells_Tissues_Organs_(2003)_173:_1-20_and_Sulik_K][VHOG] @@ -50569,7 +50807,7 @@ plexiform layer. notochordal plate - + @@ -50582,7 +50820,7 @@ plexiform layer. - + EHDAA2 @@ -50619,7 +50857,7 @@ plexiform layer. - + A midline cellular cord formed from the migration of mesenchymal cells from the primitive knot. EHDAA2:0001279 EHDAA:224 @@ -50636,14 +50874,14 @@ plexiform layer. The notochordal process grows cranially until it reaches the prechordal plate, the future site of the mouth. In this area the ectoderm is attached directly to the endoderm without intervening mesoderm. This area is known as the oropharyngeal membrane, and it will break down to become the mouth. At the other end of the primitive streak the ectoderm is also fused directly to the endoderm; this is known as the cloacal membrane (proctodeum), or primordial anus. notochordal process - + - + EHDAA2 @@ -51547,7 +51785,7 @@ plexiform layer. - + A hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood or analogs[GO,modified]. note we reserve the subclass 'heart' from the vertebrate multi-chambered heart. 'The first heart-like organ is believed to have appeared 500my ago in an ancestral bilaterian'. Amniotes: four-chambered heart. Amphibians: two atria, one ventricle, pulmonary; fish: single atrium and ventricle; amphioxus: tubular, non-striated, closed, unidirectional; ascidians: tubular, striated, open, bidirectional; arthropods: tubular, open; C elegans: contractile pharynx; Cnideria: striated muscle cells associated with gastrodermis SPD:0000130 @@ -51562,14 +51800,14 @@ plexiform layer. Gene notes: Bmp, Nkx, Gata primary circulatory organ - + - + GO uses blood circulation generically to include the haemolymphatic fluid of arthropods @@ -51724,8 +51962,8 @@ plexiform layer. - - + + @@ -51752,24 +51990,24 @@ plexiform layer. presumptive hindbrain - + - + - + XAO-abduced - + cjm @@ -51826,7 +52064,7 @@ plexiform layer. - + @@ -51845,14 +52083,14 @@ plexiform layer. presumptive midbrain hindbrain boundary - + - + ZFA @@ -51891,7 +52129,7 @@ plexiform layer. - + @@ -51908,14 +52146,14 @@ plexiform layer. presumptive segmental plate - + - + https://github.com/obophenotype/uberon/wiki/The-neural-crest EDHAA2 @@ -52014,7 +52252,7 @@ plexiform layer. - + @@ -52040,7 +52278,7 @@ plexiform layer. presumptive paraxial mesoderm - + @@ -52056,7 +52294,7 @@ plexiform layer. - + https://github.com/obophenotype/uberon/issues/1277 @@ -52138,7 +52376,7 @@ plexiform layer. - + A neural decussation that is part of a diencephalon. FMA:62446 diencephalon decussation @@ -52146,7 +52384,7 @@ plexiform layer. UBERON:0007425 decussation of diencephalon - + @@ -52159,7 +52397,7 @@ plexiform layer. - + Obol @@ -52234,7 +52472,7 @@ plexiform layer. - + Mesenchyme with little extracellular matrix. AEO:0000146 EHDAA2:0003146 @@ -52242,7 +52480,7 @@ plexiform layer. UBERON:0007524 dense mesenchyme tissue - + @@ -52255,7 +52493,7 @@ plexiform layer. - + AEO @@ -52471,6 +52709,12 @@ plexiform layer. FBbt:00005426 http://flybase.org/reports/FBrf0178740.html + + + + FBbt:00005426 + + @@ -52495,7 +52739,7 @@ plexiform layer. - + An axon tract that is part of a brain. the NIFSTD class 'nerve tract' is classified under 'regional part of brain', so it may seem like it belongs here, but actually includes spinal cord tracts FMA:83848 @@ -52505,14 +52749,14 @@ plexiform layer. UBERON:0007702 tract of brain - + - + cjm @@ -52540,7 +52784,7 @@ plexiform layer. - + Anatomical system that consists of all blood and lymph vessels. consider merging with vasculature @@ -52559,14 +52803,14 @@ plexiform layer. vascular system - + - + MA @@ -52699,7 +52943,7 @@ plexiform layer. - + @@ -52716,14 +52960,14 @@ plexiform layer. UBERON:0009142 entire embryonic mesenchyme - + - + EHDAA2 @@ -52819,8 +53063,8 @@ plexiform layer. - - + + TODO - developmental relationships for lines TAO:0007044 ZFA:0007044 @@ -52830,24 +53074,24 @@ plexiform layer. UBERON:0009615 midbrain hindbrain boundary neural plate - + - + - + ZFA - + https://github.com/obophenotype/uberon/issues/438 Bgee:AN @@ -52881,14 +53125,14 @@ plexiform layer. - + - + @@ -52913,24 +53157,24 @@ plexiform layer. presumptive midbrain - + - + - + ZFA - + ZFA @@ -52976,7 +53220,7 @@ plexiform layer. - + EHDAA2:0002094 trunk and cervical paraxial mesenchyme uberon @@ -52984,14 +53228,14 @@ plexiform layer. UBERON:0009618 trunk paraxial mesoderm - + - + EHDAA2 @@ -53013,7 +53257,7 @@ plexiform layer. - + EFO:0003704 TAO:0005041 ZFA:0005041 @@ -53023,14 +53267,14 @@ plexiform layer. anterior lateral plate mesoderm - + - + ZFA @@ -53086,14 +53330,14 @@ plexiform layer. - + EHDAA2:0001315 EHDAA:1122 uberon UBERON:0009920 optic neural crest - + @@ -53106,7 +53350,7 @@ plexiform layer. - + EHDAA2 @@ -53158,6 +53402,12 @@ plexiform layer. An anatomical structure that has more than one cell as a part. CARO:0010000 + + + + FBbt:00100313 + + @@ -53240,7 +53490,7 @@ plexiform layer. - + @@ -53265,14 +53515,14 @@ plexiform layer. eyeball of camera-type eye - + - + FMA @@ -53313,8 +53563,8 @@ plexiform layer. - - + + Portion of tissue that is dorsolateral to the floor plate and part of the midbrain. DHBA:12322 EFO:0003567 @@ -53328,11 +53578,11 @@ plexiform layer. midbrain basal plate - + - + @@ -53345,13 +53595,13 @@ plexiform layer. - + EHDAA2 - + ZFA @@ -53379,7 +53629,7 @@ plexiform layer. - + Portion of neural tube that gives rise to the midbrain. we follow ZFA in temporally dividing midbrain NT from presumptive midbrain, but in future this may be collapsed TAO:0007039 @@ -53388,14 +53638,14 @@ plexiform layer. UBERON:0010286 midbrain neural tube - + - + ZFA @@ -53422,7 +53672,7 @@ plexiform layer. - + @@ -53438,14 +53688,14 @@ plexiform layer. UBERON:0010312 immature eye - + - + definitional @@ -53691,7 +53941,7 @@ plexiform layer. processus ciliares FMA:TA - + @@ -53710,7 +53960,7 @@ plexiform layer. processus ciliares Wikipedia:Ciliary_processes - + @@ -53719,8 +53969,8 @@ plexiform layer. - - + + Anatomical cluster consisting of the skeletal elements (i.e. bone elements, cartilage elements, cartilage condensations) that are part of an individual subdivision of the organism. Excludes joints. Anatomical cluster consisting of the skeletal elements that are part of the skeleton.[VSAO] FMA:23879 @@ -53733,11 +53983,11 @@ plexiform layer. subdivision of skeleton - + - + @@ -53750,13 +54000,13 @@ plexiform layer. - + UBERONREF:0000003 - + VSAO @@ -53827,7 +54077,7 @@ plexiform layer. - + Subdivision of the skeletal system which consists of the postcranial axial skeleton plus associated joints. axial skeletal system FMA:302077 @@ -53837,7 +54087,7 @@ plexiform layer. postcranial axial skeletal system http://purl.obolibrary.org/obo/uberon/docs/The-axial-skeleton - + @@ -53850,7 +54100,7 @@ plexiform layer. - + cjm @@ -53934,12 +54184,14 @@ plexiform layer. + FBbt:00007330 FMA:67509 SCTID:91690000 uberon UBERON:0011216 + organ system subdivision @@ -53955,6 +54207,12 @@ plexiform layer. A subdivision of an anatomical system. http://orcid.org/0000-0002-6601-2165 + + + + FBbt:00007330 + + @@ -53962,7 +54220,7 @@ plexiform layer. - + Muscles within the eye (bulbus oculi).[AAO] AAO:0010038 EMAPA:18808 @@ -53973,14 +54231,14 @@ plexiform layer. UBERON:0011222 intra-ocular muscle - + - + EMAPA @@ -54233,7 +54491,7 @@ plexiform layer. textus connectivus collagenosus laxus FMA:19783 FMA:TA - + @@ -54241,7 +54499,7 @@ plexiform layer. textus connectivus laxus FMA:19783 FMA:TA - + @@ -54250,7 +54508,7 @@ plexiform layer. - + @@ -54292,7 +54550,7 @@ plexiform layer. anterior uvea - + @@ -54305,7 +54563,7 @@ plexiform layer. - + MP @@ -54662,7 +54920,6 @@ plexiform layer. The region of the organism associated with the visceral organs. - Cardinal body part, which consists of a maximal set of diverse subclasses of organ and organ part spatially associated with the vertebral column and ribcage. Examples: There is only one body proper[FMA:231424]. AEO:0000103 BTO:0001489 @@ -54672,7 +54929,6 @@ plexiform layer. body whole body UBERON:0013702 - body proper @@ -54820,6 +55076,12 @@ plexiform layer. FBC:DOS FBbt:00007278 + + + + FBbt:00007278 + + @@ -55085,7 +55347,7 @@ plexiform layer. - + @@ -55108,7 +55370,7 @@ plexiform layer. UBERON:0016887 entire extraembryonic component - + @@ -55121,7 +55383,7 @@ plexiform layer. - + AEO @@ -55612,6 +55874,12 @@ plexiform layer. Material anatomical entity consisting of multiple anatomical structures that are not connected to each other. CARO:0020000 + + + + FBbt:00007276 + + @@ -55688,7 +55956,7 @@ plexiform layer. adnexa oculi http://medical-dictionary.thefreedictionary.com/ocular+adnexa - + @@ -55727,7 +55995,7 @@ plexiform layer. structurae oculi accessoriae Wikipedia:Accessory_visual_structures - + @@ -56083,6 +56351,42 @@ plexiform layer. /////////////////////////////////////////////////////////////////////////////////////// --> + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + @@ -56113,6 +56417,26 @@ plexiform layer. + + + + + + + + + + + + + + + + + + + + diff --git a/subsets/eye_upper_slim.tsv b/subsets/eye_upper_slim.tsv index 01bb2f0dd..4b5094794 100644 --- a/subsets/eye_upper_slim.tsv +++ b/subsets/eye_upper_slim.tsv @@ -1,322 +1,320 @@ ?x ?label -_:B11339660X2D3dc4X2D4a16X2D8efaX2D5e02455511e4genid1018 -_:B11339660X2D3dc4X2D4a16X2D8efaX2D5e02455511e4genid1026 -_:B11339660X2D3dc4X2D4a16X2D8efaX2D5e02455511e4genid1033 -_:B11339660X2D3dc4X2D4a16X2D8efaX2D5e02455511e4genid1040 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+_:B0eeff062X2D4c9fX2D4f5fX2D85faX2D91dcf1dacab2genid966 "continuant" "occurrent" "independent continuant" @@ -464,7 +462,6 @@ _:B11339660X2D3dc4X2D4a16X2D8efaX2D5e02455511e4genid969 "acidophilic cytoplasm" "basophilic cytoplasm" "polychromatophilic cytoplasm" - "increased nucleus size" "conjunctival epithelial cell" "ciliary muscle cell" "central nervous system neuron" @@ -772,15 +769,10 @@ _:B11339660X2D3dc4X2D4a16X2D8efaX2D5e02455511e4genid969 "quality" "morphology" "shape" - "qualitative" - "deviation (from_normal)" - "size" "closure" "structure" "branched" "circular" - "normal" - "increased size" "closed" "elliptic" "opacity" @@ -819,8 +811,6 @@ _:B11339660X2D3dc4X2D4a16X2D8efaX2D5e02455511e4genid969 "subcylindrical" "3-D shape" "tubular" - "increased quality" - "increased object quality" "fiber shaped" "superelliptic" "acidophilic" @@ -828,6 +818,7 @@ _:B11339660X2D3dc4X2D4a16X2D8efaX2D5e02455511e4genid969 "disconnected" "cell morphology" "polymeric" + "high nuclear/cytoplasmic ratio" "cortical bipolar morphology" "bitufted dendrite cell morphology" "anatomical structure quality" diff --git a/subsets/general_cell_types_upper_slim.json b/subsets/general_cell_types_upper_slim.json index 98de6c0af..423bc976d 100644 --- a/subsets/general_cell_types_upper_slim.json +++ b/subsets/general_cell_types_upper_slim.json @@ -4,9 +4,9 @@ "meta" : { "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2002/07/owl#versionInfo", - "val" : "2024-01-04" + "val" : "2024-02-13" } ], - "version" : "http://purl.obolibrary.org/obo/cl/releases/2024-01-04/subsets/general_cell_types_upper_slim.owl" + "version" : "http://purl.obolibrary.org/obo/cl/releases/2024-02-13/subsets/general_cell_types_upper_slim.owl" }, "nodes" : [ { "id" : "http://purl.obolibrary.org/obo/BFO_0000002", @@ -731,7 +731,7 @@ "xrefs" : [ "CARO:mah" ] }, "comments" : [ "The definition of cell is intended to represent all cells, and thus a cell is defined as a material entity and not an anatomical structure, which implies that it is part of an organism (or the entirety of one)." ], - "subsets" : [ "http://purl.obolibrary.org/obo/ubprop#_upper_level" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/ubprop#_upper_level" ], "xrefs" : [ { "val" : "CALOHA:TS-2035" }, { @@ -757,6 +757,7 @@ "lbl" : "neuronal receptor cell", "type" : "CLASS", "meta" : { + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "neuronal receptor cell (sensu Animalia)" @@ -782,7 +783,7 @@ "xrefs" : [ "GOC:tfm", "MESH:D013234" ] }, "comments" : [ "This term applies to metazoan. For plant stem cells, consider using PO:0004011 ‘initial cell’ or its parent PO:0004010 ‘meristematic cell’." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "animal stem cell" @@ -807,7 +808,7 @@ "xrefs" : [ "GOC:add", "GOC:dsd", "GOC:tfm", "PMID:19022770", "http://en.wikipedia.org/wiki/Hematopoietic_stem_cell" ] }, "comments" : [ "Markers differ between species, and two sets of markers have been described for mice. HSCs are reportedly CD34-positive, CD45-positive, CD48-negative, CD150-positive, CD133-positive, and CD244-negative." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "blood forming stem cell" @@ -916,7 +917,7 @@ "xrefs" : [ "GOC:add", "ISBN:0878932437", "MESH:D023461" ] }, "comments" : [ "This cell type is intended to be compatible with any vertebrate common myeloid progenitor. For mammalian CMP known to be CD34-positive, please use the term 'common myeloid progenitor, CD34-positive' (CL_0001059)." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "common myeloid precursor" @@ -970,7 +971,7 @@ "xrefs" : [ "GOC:add", "GOC:dsd", "GOC:tfm", "PMID:10407577", "PMID:16551251" ] }, "comments" : [ "CLP are CD7-positive, CD10-positive, CD19-negative, CD34-positive, CD45RA-positive, CD79a-negative, CD127-positive, AA4.1-positive, RAG-negative, Sca-1-low, sIgM-negative, sIgD-negative, TdT-negative, Vpre-B-negative, and pre-BCR-negative. Expression of transcription factors include E2A-positive, EBF-positive, Ikaros-negative, PU.1-negative, and Pax5-negative." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "common lymphocyte precursor" @@ -1035,6 +1036,7 @@ "xrefs" : [ "SANBI:mhl" ] }, "comments" : [ "define using PATO mulit-potent or oligopotent?" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "blast cell" @@ -1076,7 +1078,7 @@ "xrefs" : [ "ISBN:0517223651", "MESH:D005347", "http://en.wikipedia.org/wiki/Fibroblast" ] }, "comments" : [ "These cells may be vimentin-positive, fibronectin-positive, fsp1-positive, MMP-1-positive, collagen I-positive, collagen III-positive, and alpha-SMA-negative." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { "val" : "BTO:0000452" }, { @@ -1102,7 +1104,7 @@ "val" : "A cell that is usually found in a two-dimensional sheet with a free surface. The cell has a cytoskeleton that allows for tight cell to cell contact and for cell polarity where apical part is directed towards the lumen and the basal part to the basal lamina.", "xrefs" : [ "FB:ma", "GOC:tfm", "MESH:D004847" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "epitheliocyte" @@ -1137,7 +1139,7 @@ "val" : "A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube.", "xrefs" : [ "GO:0002065", "https://orcid.org/0000-0001-5208-3432" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" @@ -1152,7 +1154,7 @@ "val" : "A cell found predominately in the blood.", "xrefs" : [ "GOC:add", "GOC:tfm" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim" ], "xrefs" : [ { "val" : "FMA:62844" }, { @@ -1168,7 +1170,7 @@ "val" : "A type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex.", "xrefs" : [ "GOC:add", "GOC:tfm", "ISBN:0781735149" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "T lymphocyte" @@ -1211,6 +1213,7 @@ "xrefs" : [ "GOC:add", "GOC:tfm", "GO_REF:0000031", "ISBN:0781735149", "PMID:10428500", "PMID:15055519", "PMID:17380158" ] }, "comments" : [ "Morphology: Highly vesicular; markers: Surface: RANK, cFMS (MCSF receptor); Secreted: cathepsin K and TRAP (tartate resistant acid phosphatase); transcription factors: PU.1, cFOS, MITF, NFkB (p52); role or process: tissue remodelling: bone resorption; lineage: hematopoietic, myeloid." ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "chondroclast" @@ -1234,7 +1237,7 @@ "val" : "A leukocyte with abundant granules in the cytoplasm.", "xrefs" : [ "GOC:amm", "GOC:tfm", "MESH:D006098", "http://en.wikipedia.org/wiki/Granulocyte" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "granular leucocyte" @@ -1262,7 +1265,10 @@ }, { "id" : "http://purl.obolibrary.org/obo/CL_0000095", "lbl" : "neuron associated cell", - "type" : "CLASS" + "type" : "CLASS", + "meta" : { + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] + } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000100", "lbl" : "motor neuron", @@ -1272,7 +1278,7 @@ "val" : "An efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes or inhibits movement.", "xrefs" : [ "MESH:D009046", "PMID:16875686" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "motoneuron" @@ -1321,7 +1327,7 @@ "val" : "A vertebrate phagocyte with a single nucleus.", "xrefs" : [ "GOC:add", "GOC:tfm", "ISBN:0781735149" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { "val" : "BTO:0001433" } ], @@ -1340,7 +1346,7 @@ "xrefs" : [ "MESH:D009457" ] }, "comments" : [ "Not all glial cells develop from glioblasts, with microglia developing from the mesoderm instead. See https://github.com/obophenotype/cell-ontology/issues/1571" ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "neuroglial cell" @@ -1382,6 +1388,7 @@ "xrefs" : [ "FB:ma", "GOC:dsd", "PMCID:PMC2613570", "PMID:10102814", "PMID:16923606", "PMID:17986482", "PMID:19960544", "http://en.wikipedia.org/wiki/Mesenchymal_stem_cell", "http://www.copewithcytokines.de/cope.cgi?key=mesenchymal%20stem%20cells" ] }, "comments" : [ "Many but not all mesenchymal cells derive from the mesoderm. MSCs are reportedly CD3-negative, CD4-negative, CD5-negative, CD8-negative, CD11a-negative, CD11b-negative, CD14-negative, CD19-negative, CD29-positive, CD31-negative, CD34-negative, CD38-negative, CD40-negative, CD44-positive, CD45-negative, CD49-positive, CD54-positive, CD66b-negative, CD79a-negative, CD80-negative, CD102-positive, CD106-positive, CD117-positive, CD121a-positive, CD121b-positive, CD123-positive, CD124-positive, CD133-negative, CD146-positive, CD166-positive, CD271-positive, B220-negative, Gr1-negative, MHCI-positive, MHCII-negative, SSEA4-negative, sca1-positive, Ter119-negative, and glycophorin A-negative. Cultured MSCs are capable of producing stem cell factor, IL7, IL8, IL11, TGF-beta, cofilin, galectin-1, laminin-receptor 1, cyclophilin A, and MMP-2." ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "bone marrow stromal cells" @@ -1450,7 +1457,7 @@ "val" : "A fat-storing cell found mostly in the abdominal cavity and subcutaneous tissue of mammals. Fat is usually stored in the form of triglycerides.", "xrefs" : [ "MESH:D017667" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "adipose cell" @@ -1480,7 +1487,7 @@ "xrefs" : [ "GOC:add", "ISBN:0781735149" ] }, "comments" : [ "Note change of name; nearly all somatic cells can present antigens to T cells via MHC Class I complexes leading to effector responses, but professional antigen presenting cells constitutively express MHC Class II as well as costimulatory molecules, and thus can initiate immune responses via T cells." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003000", "pred" : "hasRelatedSynonym", @@ -1516,7 +1523,7 @@ "val" : "A pigment cell derived from the neural crest. Contains melanin-filled pigment granules, which gives a brown to black appearance.", "xrefs" : [ "SANBI:mhl" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "melanophore" @@ -1556,6 +1563,7 @@ "val" : "A cell that specializes in controlled release of one or more substances.", "xrefs" : [ "GOC:tfm", "ISBN:0721662544" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "BTO:0003659" }, { @@ -1585,7 +1593,7 @@ "val" : "A cell of an endocrine gland, ductless glands that secrete substances which are released directly into the circulation and which influence metabolism and other body functions.", "xrefs" : [ "MESH:D055098" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "endocrinocyte" @@ -1606,7 +1614,8 @@ "definition" : { "val" : "A cell whose primary function is to shorten.", "xrefs" : [ "FB:ma" ] - } + }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000187", @@ -1617,6 +1626,7 @@ "val" : "A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns.", "xrefs" : [ "MESH:D032342" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "muscle fiber" @@ -1651,7 +1661,7 @@ "val" : "A somatic cell located in skeletal muscle.", "xrefs" : [ "GOC:tfm" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "skeletal muscle cell" @@ -1677,7 +1687,7 @@ "val" : "A non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels. They develop from specialized myoblasts (smooth muscle myoblast).", "xrefs" : [ "MESH:D032389", "PMID:9315361", "http://en.wikipedia.org/wiki/Smooth_muscle_cell" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "non-striated muscle cell" @@ -1730,6 +1740,7 @@ "val" : "A cell specialized to detect and transduce light.", "xrefs" : [ "MESH:D010786" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "BTO:0001060" }, { @@ -1788,6 +1799,7 @@ "val" : "A cell of the middle germ layer of the embryo.", "xrefs" : [ "MESH:D008648" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "mesoblast" @@ -1860,6 +1872,7 @@ "val" : "Any cell capable of ingesting particulate matter via phagocytosis.", "xrefs" : [ "GOC:add", "ISBN:0721601464" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "BTO:0001044" }, { @@ -1878,7 +1891,7 @@ "xrefs" : [ "GOC:add", "GOC:tfm", "GO_REF:0000031", "PMID:16213494", "PMID:1919437" ] }, "comments" : [ "Morphology: Diameter 30_M-80 _M, abundant cytoplasm, low N/C ratio, eccentric nucleus. Irregular shape with pseudopods, highly adhesive. Contain vacuoles and phagosomes, may contain azurophilic granules; markers: Mouse & Human: CD68, in most cases CD11b. Mouse: in most cases F4/80+; role or process: immune, antigen presentation, & tissue remodelling; lineage: hematopoietic, myeloid." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "histiocyte" @@ -1908,7 +1921,7 @@ "val" : "A lymphocyte of B lineage that is capable of B cell mediated immunity.", "xrefs" : [ "GOC:add", "GOC:tfm", "GO_REF:0000031", "ISBN:0781735149" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "B lymphocyte" @@ -1940,6 +1953,7 @@ "lbl" : "eukaryotic cell", "type" : "CLASS", "meta" : { + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "MESH:D005057" } ] @@ -2053,7 +2067,7 @@ "val" : "A cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation. These cells are lineage negative (CD3-negative, CD19-negative, CD34-negative, and CD56-negative).", "xrefs" : [ "GOC:add", "ISBN:0781735149" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "interdigitating cell" @@ -2094,7 +2108,7 @@ "val" : "A connective tissue cell of an organ found in the loose connective tissue. These are most often associated with the uterine mucosa and the ovary as well as the hematopoietic system and elsewhere.", "xrefs" : [ "GOC:tfm", "MESH:D017154" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { "val" : "BTO:0002064" }, { @@ -2114,6 +2128,7 @@ "val" : "A precursor cell destined to differentiate into cardiac muscle cell.", "xrefs" : [ "GOC:tfm", "MESH:D032386" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cardiac muscle progenitor cell" @@ -2134,6 +2149,7 @@ "val" : "A precursor cell destined to differentiate into smooth muscle myocytes.", "xrefs" : [ "GOC:tfm", "MESH:D032390" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "myoblast, smooth muscle", @@ -2219,7 +2235,7 @@ "xrefs" : [ "MESH:D009474", "http://en.wikipedia.org/wiki/Neuron" ] }, "comments" : [ "These cells are also reportedly CD4-negative and CD200-positive. They are also capable of producing CD40L and IFN-gamma." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "nerve cell" @@ -2271,7 +2287,7 @@ "xrefs" : [ "GOC:add", "ISBN:0683073696", "ISBN:0781735149" ] }, "comments" : [ "Editors note: consider adding taxon constraint to vertebrata (PMID:18025161)" ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { "val" : "BTO:0000775" }, { @@ -2298,7 +2314,7 @@ "xrefs" : [ "GOC:amm", "GOC:dsd", "GOC:tfm", "GO_REF:0000031", "ISBN:0721601464", "MESH:D055014", "PMCID:PMC2213186", "PMCID:PMC548021", "PMID:16551251", "PMID:16647566", "http://en.wikipedia.org/wiki/CFU-GM", "http://www.copewithcytokines.de" ] }, "comments" : [ "Originally described in the dendritic cell ontology (DC_CL:0000042)(PMID:19243617). GMPs are reportedly CD16-positive, CD32-positive, CD34-positive, CD38-positive, CD45RA-positive, CD110-negative, CD117-positive, CD123-positive, and SCA1-negative." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "CFU-C , Colony forming unit in culture", @@ -2343,7 +2359,7 @@ "xrefs" : [ "GOC:tfm", "ISBN:0721601464" ] }, "comments" : [ "Morphology: Mononuclear cell, diameter 14-18 _M, fine azurophilic granules; markers: CD11b (shared with many other myeloid cells); location: Adult: bone marrow; Fetal: Liver, Yolk Sac; role or process: hematopoiesis, monocyte development; lineage: hematopoietic, myeloid." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { "val" : "BTO:0004657" }, { @@ -2382,7 +2398,7 @@ "xrefs" : [ "GO_REF:0000031", "MESH:D009000" ] }, "comments" : [ "Morphology: Mononuclear cell, diameter, 14 to 20 _M, N/C ratio 2:1-1:1. Nucleus may appear in variety of shapes: round, kidney, lobulated, or convoluted. Fine azurophilic granules present; markers: CD11b (shared with other myeloid cells), human: CD14, mouse: F4/80-mid,GR1-low; location: Blood, but can be recruited into tissues; role or process: immune & tissue remodelling; lineage: hematopoietic, myeloid." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { "val" : "BTO:0000876" }, { @@ -2404,7 +2420,7 @@ "val" : "A lymphocyte that can spontaneously kill a variety of target cells without prior antigenic activation via germline encoded activation receptors and also regulate immune responses via cytokine release and direct contact with other cells.", "xrefs" : [ "GOC:add", "ISBN:0781735149", "PMID:15771571" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "large granular lymphocyte" @@ -2443,7 +2459,8 @@ "definition" : { "val" : "A non-terminally differentiated cell that is capable of developing into a muscle cell.", "xrefs" : [ "GOC:add" ] - } + }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000723", @@ -2486,7 +2503,7 @@ "val" : "An achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue.", "xrefs" : [ "GOC:add", "GOC:tfm", "ISBN:978-0-323-05290-0" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "leucocyte" @@ -2523,7 +2540,7 @@ "xrefs" : [ "GOC:mtg_cardiacconduct_nov11", "GOC:tfm", "ISBN:0323052908", "PMID:22426062", "PMID:4711263" ] }, "comments" : [ "This class encompasses the muscle cells responsible for heart* contraction in both vertebrates and arthropods. The ultrastucture of a wide range of arthropod heart cells has been examined including spiders, horseshoe crabs, crustaceans (see Sherman, 1973 and refs therein) and insects (see Lehmacher et al (2012) and refs therein). According to these refs, the cells participating in heart contraction in all cases are transversely striated. Insects hearts additionally contain ostial cells, also transversely striated muscle cells, but which do not participate in heart contraction." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "cardiocyte" @@ -2567,6 +2584,7 @@ "val" : "A cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage.", "xrefs" : [ "GOC:add" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "BTO:0001441" }, { @@ -2583,7 +2601,8 @@ "definition" : { "val" : "A cell of the monocyte, granulocyte, or mast cell lineage.", "xrefs" : [ "GOC:add" ] - } + }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000775", @@ -2594,7 +2613,7 @@ "val" : "Any of the immature or mature forms of a granular leukocyte that in its mature form has a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes.", "xrefs" : [ "GOC:add", "GOC:amm", "GOC:tfm", "ISBN:0721601464" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "PMN" @@ -2656,6 +2675,7 @@ "xrefs" : [ "GOC:add", "PMID:10449155", "PMID:17332250", "PMID:9521319" ] }, "comments" : [ "These cells are CD1a-negative, CD1b-positive, CD11a-positive, CD11c-positive, CD13-positive, CD14-negative, CD20-negative, CD21-negative, CD33-positive, CD40-negative, CD50-positive, CD54-positive, CD58-positive, CD68-negative, CD80-negative, CD83-negative, CD85j-positive, CD86-positive, CD89-negative, CD95-positive, CD120a-negative, CD120b-positive, CD123-negative, CD178-negative, CD206-negative, CD207-negative, CD209-negative, and TNF-alpha-negative. Upon TLR stimulation, they are capable of producing high levels of TNF-alpha, IL-6, CXCL8 (IL-8)." ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "interdigitating cell" @@ -2713,7 +2733,7 @@ "xrefs" : [ "GOC:add", "GOC:dsd", "ISBN:0781735149", "PMID:12633665", "PMID:16551251", "PMID:18432934" ] }, "comments" : [ "Human pro-B cells are reportedly CD10-positive, CD22-positive, CD34-positive, CD38-positive, CD45-low, CD48-positive, CD79a-positive, CD127-positive, CD184-positive, RAG-positive, TdT-positive, Vpre-B-positive, pre-BCR-negative, IgD-negative, and IgM-negative. Transcription factors expressed: Pax5-positive, EBF-positive, E2A-negative, Ikaros-negative, and PU.1-negative." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "pre-pro B cell", @@ -2761,6 +2781,7 @@ "val" : "A lymphoid progenitor cell of the T cell lineage, with some lineage specific marker expression, but not yet fully committed to the T cell lineage.", "xrefs" : [ "GOC:add", "ISBN:0781735149" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "pro-T lymphocyte" @@ -2788,7 +2809,7 @@ "xrefs" : [ "GOC:add", "GOC:tfm", "PMID:19022770" ] }, "comments" : [ "Markers differ between mouse and human." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "MPP" @@ -2816,6 +2837,7 @@ "xrefs" : [ "GOC:add", "GOC:tfm" ] }, "comments" : [ "Note that this is a class of cell types, not an identified single cell type." ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "lymphoid progenitor cell" @@ -2838,7 +2860,7 @@ "xrefs" : [ "GOC:add", "GOC:tfm", "PMID:19022770" ] }, "comments" : [ "Note that this is a class of cell types, not an identified single cell type." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "myeloid progenitor cell" @@ -2864,7 +2886,7 @@ "val" : "A leukocyte with a single non-segmented nucleus in the mature form.", "xrefs" : [ "GOC:add" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "mononuclear leukocyte" @@ -2905,6 +2927,7 @@ "val" : "A cell of a hematopoietic lineage.", "xrefs" : [ "GOC:add", "GO_REF:0000031" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "haematopoietic cell" @@ -2935,7 +2958,7 @@ "xrefs" : [ "GOC:amm", "GO_REF:0000031", "PMID:17850486" ] }, "comments" : [ "Originally described in the dendritic cell ontology (DC_CL:0000003)(PMID:19243617) These cells are also CD20-negative, MHCII-positive." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "interdigitating cell" @@ -3017,7 +3040,7 @@ "val" : "A lymphocyte that lacks characteristic T cell, B cell, myeloid cell, and dendritic cell markers, that functions as part of the innate immune response to produce cytokines and other effector responses.", "xrefs" : [ "GOC:add", "GOC:dsd", "PMID:23292121", "PMID:23348417" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" @@ -3059,6 +3082,7 @@ "val" : "A progenitor cell that can give rise to plasmacytoid and myeloid dendritic cells, and to monocytes and macrophages.", "xrefs" : [ "GOC:tfm", "PMID:19273628" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "MDP" @@ -3138,6 +3162,7 @@ "xrefs" : [ "GOC:tfm", "ISBN:0618947256" ] }, "comments" : [ "MH consider whether bone marrow cells are bone cells in the structural sense vs. being part of bone organ sense." ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "BTO:0004850" }, { @@ -3202,6 +3227,7 @@ "val" : "A cell that is part of the nervous system.", "xrefs" : [ "GOC:tfm", "ISBN:0618947256" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "CALOHA:TS-2040" }, { @@ -3224,6 +3250,7 @@ "val" : "A cell of the supporting or framework tissue of the body, arising chiefly from the embryonic mesoderm and including adipose tissue, cartilage, and bone.", "xrefs" : [ "GOC:tfm", "ISBN:0618947256" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "CALOHA:TS-2096" }, { @@ -3379,7 +3406,8 @@ "definition" : { "val" : "Any hematopoietic cell that is a precursor of some other hematopoietic cell type.", "xrefs" : [ "GOC:dos" ] - } + }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0008002", @@ -3390,6 +3418,7 @@ "val" : "A transversely striated, synctial cell of skeletal muscle. It is formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.", "xrefs" : [ "GOC:tfm", "ISBN:0323052908" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "MESH:D018485" } ] @@ -3415,7 +3444,7 @@ "definition" : { "val" : "A non-polarised cell precursor cell that is part of some mesenchyme, is associated with the cell matrix but is not connected to other cells and is capable of migration." }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "mesenchyme cell" @@ -3472,7 +3501,8 @@ "definition" : { "val" : "A cell of the neural crest. Neural crest cells are multipotent. Premigratory neural crest cells are found at the neural plate boarder, some of which will undergo ectomesynchymal transition and delamination to form migratory neural crest cells.", "xrefs" : [ "https://orcid.org/0000-0001-5208-3432", "https://orcid.org/0000-0002-9900-7880" ] - } + }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0011026", @@ -3483,6 +3513,7 @@ "val" : "A precursor cell that has a tendency to differentiate into a specific type of cell. They are descendants of stem cells, only they are more constrained in their differentiation potential or capacity for self-renewal, and are often more limited in both senses.", "xrefs" : [ "ISBN:978-1-62808-994-3", "https://doi.org/10.1016/B978-0-12-409503-8.00002-0" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0001-5208-3432" @@ -3497,7 +3528,8 @@ "val" : "A cell that, by division or terminal differentiation, can give rise to other cell types.", "xrefs" : [ "GOC:dos" ] }, - "comments" : [ "Work is needed on GO 'cell differentiation' before it is clear whether the equivalent class definition 'native cell' that capable_of some 'cell differentiation' works. Also, may want to consider merging this with non-terminally differentiated cell." ] + "comments" : [ "Work is needed on GO 'cell differentiation' before it is clear whether the equivalent class definition 'native cell' that capable_of some 'cell differentiation' works. Also, may want to consider merging this with non-terminally differentiated cell." ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0017500", @@ -3533,23 +3565,6 @@ "val" : "2009-12-22T04:24:54Z" } ] } - }, { - "id" : "http://purl.obolibrary.org/obo/CL_0017505", - "lbl" : "increased nucleus size", - "type" : "CLASS", - "meta" : { - "definition" : { - "val" : "A nucleus size quality which is relatively high compared to the amount of cytoplasm present in the same cell.", - "xrefs" : [ "GOC:tfm" ] - }, - "basicPropertyValues" : [ { - "pred" : "http://purl.org/dc/terms/contributor", - "val" : "https://orcid.org/0000-0003-1980-3228" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", - "val" : "2009-12-23T10:53:24Z" - } ] - } }, { "id" : "http://purl.obolibrary.org/obo/CL_1001610", "lbl" : "bone marrow hematopoietic cell", @@ -4551,7 +4566,7 @@ "type" : "CLASS", "meta" : { "definition" : { - "val" : "A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex).", + "val" : "A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex).", "xrefs" : [ "GOC:pdt" ] }, "comments" : [ "Note that, in addition to forming the root of the cellular component ontology, this term is recommended for the annotation of gene products whose cellular component is unknown. When this term is used for annotation, it indicates that no information was available about the cellular component of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this." ], @@ -4591,7 +4606,7 @@ "xrefs" : [ "GOC:go_curators" ] }, "comments" : [ "Note that this term is intended to annotate gene products that are not attached to the cell surface. For gene products from multicellular organisms which are secreted from a cell but retained within the organism (i.e. released into the interstitial fluid or blood), consider the cellular component term 'extracellular space ; GO:0005615'." ], - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_yeast", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "extracellular" @@ -4749,7 +4764,7 @@ "xrefs" : [ "ISBN:0198547684" ] }, "comments" : [ "Chromosomes include parts that are not part of the chromatin. Examples include the kinetochore." ], - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_yeast", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "interphase chromosome" @@ -4797,7 +4812,7 @@ "val" : "The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.", "xrefs" : [ "ISBN:0198547684" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_yeast", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "xrefs" : [ { "val" : "Wikipedia:Cytoplasm" } ], @@ -4880,7 +4895,7 @@ "val" : "The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.", "xrefs" : [ "ISBN:0716731363" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_yeast", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "juxtamembrane" @@ -4995,7 +5010,7 @@ "val" : "Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction.", "xrefs" : [ "ISBN:0198506732" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_pombe", "http://purl.obolibrary.org/obo/go#goslim_yeast", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_pombe", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" @@ -5011,7 +5026,7 @@ "xrefs" : [ "GOC:dos", "GOC:dph", "GOC:jl", "GOC:mah" ] }, "comments" : [ "Note that this term should not be used for direct annotation. It should be possible to make a more specific annotation to one of the children of this term, for e.g. to transmembrane transport, to microtubule-based transport or to vesicle-mediated transport." ], - "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "single-organism transport" @@ -6605,7 +6620,7 @@ "xrefs" : [ "GOC:mtg_signal", "GOC:mtg_signaling_feb11", "GOC:signaling" ] }, "comments" : [ "Note that a signal is any variable property or parameter that serves to convey information, and may be a physical entity such as a gene product or small molecule, a photon, or a change in state such as movement or voltage change." ], - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pombe", "http://purl.obolibrary.org/obo/go#goslim_yeast", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pombe", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "biological signaling" @@ -6705,7 +6720,7 @@ "val" : "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon.", "xrefs" : [ "GOC:jl", "GOC:mah", "http://www.cogsci.princeton.edu/~wn/" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cell projection organisation" @@ -7029,7 +7044,7 @@ "val" : "A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues.", "xrefs" : [ "GOC:BHF", "GOC:mah", "GOC:rph", "NIF_Subcellular:nlx_subcell_20090513", "PMID:21123617", "PMID:28089324" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "proteinaceous extracellular matrix" @@ -7759,7 +7774,7 @@ "val" : "A prolongation or process extending from a cell, e.g. a flagellum or axon.", "xrefs" : [ "GOC:jl", "http://www.cogsci.princeton.edu/~wn/" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "cell process" @@ -7815,7 +7830,7 @@ "val" : "The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.", "xrefs" : [ "GOC:mah" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_pir" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_pir" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "biopolymer metabolic process", @@ -7831,6 +7846,9 @@ "val" : "multicellular organismal macromolecule metabolic process" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/26424" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0034960" }, { @@ -7867,7 +7885,7 @@ "val" : "Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane.", "xrefs" : [ "GOC:go_curators" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "xrefs" : [ { "val" : "NIF_Subcellular:sao1539965131" }, { @@ -8553,12 +8571,15 @@ "val" : "The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.", "xrefs" : [ "GO_REF:0000021" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_plant" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_plant" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "development of an anatomical structure" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/26424" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] @@ -8586,7 +8607,7 @@ "val" : "Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another.", "xrefs" : [ "GOC:dgh", "GOC:dph", "GOC:isa_complete", "GOC:mlg" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cell locomotion" @@ -8767,7 +8788,7 @@ "xrefs" : [ "GOC:ai", "GOC:bf" ] }, "comments" : [ "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ], - "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_manually_annotate", "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_manually_annotate", "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "physiological response to stimulus" @@ -9156,7 +9177,7 @@ "val" : "A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.", "xrefs" : [ "GOC:dph", "GOC:tb" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_pombe", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_pombe", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cellular membrane organisation" @@ -9332,6 +9353,7 @@ "val" : "The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon.", "xrefs" : [ "GOC:mah" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "organic molecular entity metabolic process" @@ -9343,6 +9365,9 @@ "val" : "organic substance metabolism" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/26424" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "mah" }, { @@ -9395,7 +9420,7 @@ "type" : "CLASS", "meta" : { "definition" : { - "val" : "The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures.", + "val" : "The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures.", "xrefs" : [ "GOC:pdt" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon" ], @@ -9532,7 +9557,7 @@ "val" : "Reactions triggered in response to the presence of another organism that act to protect the cell or organism from damage caused by that organism.", "xrefs" : [ "GOC:dos" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "defence response incompatible interaction" @@ -9884,6 +9909,9 @@ "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/24200" + }, { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/26424" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "kmv" @@ -9986,6 +10014,29 @@ "val" : "biological_process" } ] } + }, { + "id" : "http://purl.obolibrary.org/obo/GO_0140546", + "lbl" : "defense response to symbiont", + "type" : "CLASS", + "meta" : { + "definition" : { + "val" : "Reactions triggered in response to the presence of a symbiont that act to protect or prevent damage to the host.", + "xrefs" : [ "GOC:pg" ] + }, + "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/20261" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", + "val" : "pg" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", + "val" : "2020-11-11T17:19:06Z" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "biological_process" + } ] + } }, { "id" : "http://purl.obolibrary.org/obo/GO_1901576", "lbl" : "organic substance biosynthetic process", @@ -11496,47 +11547,6 @@ "val" : "quality" } ] } - }, { - "id" : "http://purl.obolibrary.org/obo/PATO_0000068", - "lbl" : "qualitative", - "type" : "CLASS", - "meta" : { - "comments" : [ "TODO: define this or obsolete it and move children somewhere else." ], - "basicPropertyValues" : [ { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", - "val" : "quality" - } ] - } - }, { - "id" : "http://purl.obolibrary.org/obo/PATO_0000069", - "lbl" : "deviation (from_normal)", - "type" : "CLASS", - "meta" : { - "definition" : { - "val" : "A quality inhering in a bearer by virtue of the whether the bearer differs from normal or average.", - "xrefs" : [ "PATOC:GVG" ] - }, - "subsets" : [ "http://purl.obolibrary.org/obo/pato#attribute_slim" ], - "basicPropertyValues" : [ { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", - "val" : "quality" - } ] - } - }, { - "id" : "http://purl.obolibrary.org/obo/PATO_0000117", - "lbl" : "size", - "type" : "CLASS", - "meta" : { - "definition" : { - "val" : "A morphology quality inhering in a bearer by virtue of the bearer's physical magnitude.", - "xrefs" : [ "WordNet:WordNet" ] - }, - "subsets" : [ "http://purl.obolibrary.org/obo/pato#attribute_slim", "http://purl.obolibrary.org/obo/pato#scalar_slim" ], - "basicPropertyValues" : [ { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", - "val" : "quality" - } ] - } }, { "id" : "http://purl.obolibrary.org/obo/PATO_0000141", "lbl" : "structure", @@ -11585,65 +11595,6 @@ "val" : "quality" } ] } - }, { - "id" : "http://purl.obolibrary.org/obo/PATO_0000461", - "lbl" : "normal", - "type" : "CLASS", - "meta" : { - "definition" : { - "val" : "A quality inhering in a bearer by virtue of the bearer's exhibiting no deviation from normal or average.", - "xrefs" : [ "PATOC:GVG" ] - }, - "subsets" : [ "http://purl.obolibrary.org/obo/pato#abnormal_slim", "http://purl.obolibrary.org/obo/pato#mpath_slim", "http://purl.obolibrary.org/obo/pato#value_slim" ], - "synonyms" : [ { - "pred" : "hasRelatedSynonym", - "val" : "average" - } ], - "basicPropertyValues" : [ { - "pred" : "http://purl.obolibrary.org/obo/RO_0002604", - "val" : "http://purl.obolibrary.org/obo/PATO_0000460" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", - "val" : "quality" - } ] - } - }, { - "id" : "http://purl.obolibrary.org/obo/PATO_0000586", - "lbl" : "increased size", - "type" : "CLASS", - "meta" : { - "definition" : { - "val" : "A size quality which is relatively high.", - "xrefs" : [ "PATOC:GVG" ] - }, - "subsets" : [ "http://purl.obolibrary.org/obo/pato#value_slim" ], - "synonyms" : [ { - "pred" : "hasRelatedSynonym", - "val" : "big" - }, { - "pred" : "hasRelatedSynonym", - "val" : "enlarged" - }, { - "pred" : "hasRelatedSynonym", - "val" : "expanded" - }, { - "pred" : "hasRelatedSynonym", - "val" : "great" - }, { - "pred" : "hasRelatedSynonym", - "val" : "large" - } ], - "basicPropertyValues" : [ { - "pred" : "http://purl.obolibrary.org/obo/RO_0002604", - "val" : "http://purl.obolibrary.org/obo/PATO_0000587" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", - "val" : "PATO:0001202" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", - "val" : "quality" - } ] - } }, { "id" : "http://purl.obolibrary.org/obo/PATO_0000947", "lbl" : "elliptic", @@ -12184,52 +12135,6 @@ "val" : "quality" } ] } - }, { - "id" : "http://purl.obolibrary.org/obo/PATO_0002300", - "lbl" : "increased quality", - "type" : "CLASS", - "meta" : { - "definition" : { - "val" : "A quality that has a value that is increased compared to normal or average.", - "xrefs" : [ "PATOC:GVG" ] - }, - "basicPropertyValues" : [ { - "pred" : "http://purl.obolibrary.org/obo/RO_0002604", - "val" : "http://purl.obolibrary.org/obo/PATO_0002301" - }, { - "pred" : "http://purl.org/dc/terms/contributor", - "val" : "https://orcid.org/0000-0002-2061-091X" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", - "val" : "2011-06-16T06:39:43Z" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", - "val" : "quality" - } ] - } - }, { - "id" : "http://purl.obolibrary.org/obo/PATO_0002305", - "lbl" : "increased object quality", - "type" : "CLASS", - "meta" : { - "definition" : { - "val" : "A quality of an object that has a value that is increased compared to normal or average.", - "xrefs" : [ "PATOC:GVG" ] - }, - "basicPropertyValues" : [ { - "pred" : "http://purl.obolibrary.org/obo/RO_0002604", - "val" : "http://purl.obolibrary.org/obo/PATO_0002303" - }, { - "pred" : "http://purl.org/dc/terms/contributor", - "val" : "https://orcid.org/0000-0002-2061-091X" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", - "val" : "2011-06-16T06:54:01Z" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", - "val" : "quality" - } ] - } }, { "id" : "http://purl.obolibrary.org/obo/PATO_0002309", "lbl" : "fiber shaped", @@ -12354,6 +12259,28 @@ "val" : "quality" } ] } + }, { + "id" : "http://purl.obolibrary.org/obo/PATO_0040072", + "lbl" : "high nuclear/cytoplasmic ratio", + "type" : "CLASS", + "meta" : { + "definition" : { + "val" : "A quality inhering in a cell by virtue of the cell having a high nuclear/cytoplasmic ratio.", + "xrefs" : [ "Wikipedia:NC_ratio&oldid=931936284", "http://lymerick.net/blood-cells.pdf" ] + }, + "comments" : [ "A high nuclear/cytolasmic ratio is 70% or higher." ], + "synonyms" : [ { + "pred" : "hasExactSynonym", + "val" : "high N:C ratio" + } ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", + "val" : "http://orcid.org/0000-0001-5208-3432" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "quality" + } ] + } }, { "id" : "http://purl.obolibrary.org/obo/PATO_0070044", "lbl" : "anatomical structure quality", @@ -16230,6 +16157,9 @@ "val" : "inverse of develops from" }, "subsets" : [ "http://purl.obolibrary.org/obo/RO_0002259" ], + "xrefs" : [ { + "val" : "RO:0002203" + } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000114", "val" : "http://purl.obolibrary.org/obo/IAO_0000125" @@ -16242,6 +16172,12 @@ }, { "pred" : "http://purl.obolibrary.org/obo/IAO_0000117", "val" : "https://orcid.org/0000-0003-1980-3228" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "uberon" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#shorthand", + "val" : "develops_into" } ] } }, { @@ -20706,7 +20642,7 @@ "val" : "sinew", "xrefs" : [ "Wikipedia:Tendon" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "tendo", "xrefs" : [ "Wikipedia:Tendon" ] @@ -21456,7 +21392,7 @@ "val" : "zygote", "xrefs" : [ "VHOG:0000745" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "zygotum", "xrefs" : [ "Wikipedia:Zygote" ] @@ -21733,7 +21669,7 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#efo_slim", "http://purl.obolibrary.org/obo/uberon/core#major_organ", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "regio oralis", "xrefs" : [ "BTO:0004698", "FMA:49184", "FMA:TA" ] @@ -21741,7 +21677,7 @@ "pred" : "hasNarrowSynonym", "val" : "adult mouth" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "cavital oralis", "xrefs" : [ "Wikipedia:Mouth" ] @@ -22640,8 +22576,6 @@ "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#common_anatomy", "http://purl.obolibrary.org/obo/uberon/core#upper_level" ], "xrefs" : [ { "val" : "FBbt:00007277" - }, { - "val" : "IDOMAL:0002461" }, { "val" : "VHOG:0001737" } ], @@ -23890,7 +23824,7 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "systema cardiovasculare", "xrefs" : [ "Wikipedia:Circulatory_system" ] @@ -23899,6 +23833,8 @@ "val" : "AAO:0000959" }, { "val" : "CALOHA:TS-2103" + }, { + "val" : "MESH:D002319" }, { "val" : "VHOG:0001248" }, { @@ -23956,7 +23892,7 @@ "pred" : "hasExactSynonym", "val" : "musculature" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "musculi", "xrefs" : [ "FMA:32558", "FMA:TA" ] @@ -24030,7 +23966,7 @@ "val" : "The nervous system is an organ system containing predominantly neuron and glial cells. In bilaterally symmetrical organism, it is arranged in a network of tree-like structures connected to a central body. The main functions of the nervous system are to regulate and control body functions, and to receive sensory input, process this information, and generate behavior [CUMBO].", "xrefs" : [ "BIRNLEX:844", "ISBN:0-14-051288-8", "ISBN:3110148986", "NLM:nervous+system", "WB:rynl", "Wikipedia:Nervous_system", "ZFIN:curator" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#cumbo", "http://purl.obolibrary.org/obo/uberon/core#efo_slim", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], + "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#cumbo", "http://purl.obolibrary.org/obo/uberon/core#efo_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "neurological system", @@ -24040,7 +23976,7 @@ "val" : "nerve net", "xrefs" : [ "Wikipedia:Nerve_net" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "systema nervosum", "xrefs" : [ "Wikipedia:Nervous_system" ] @@ -24103,6 +24039,9 @@ "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_6040" + }, { + "pred" : "http://purl.obolibrary.org/obo/RO_0002175", + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" }, { "pred" : "http://purl.obolibrary.org/obo/UBPROP_0000001", "val" : "A regulatory system of the body that consists of neurons and neuroglial cells. The nervous system is divided into two parts, the central nervous system (CNS) and the peripheral nervous system (PNS). (Source: BioGlossary, www.Biology-Text.com)[TAO]" @@ -24138,13 +24077,13 @@ "val" : "The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the neural tube derivatives: the brain and spinal cord. In invertebrates it includes central ganglia plus nerve cord.", "xrefs" : [ "GO:0021551", "http://www.frontiersinzoology.com/content/7/1/29", "https://sourceforge.net/p/geneontology/ontology-requests/11422/" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#cumbo", "http://purl.obolibrary.org/obo/uberon/core#efo_slim", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], + "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#cumbo", "http://purl.obolibrary.org/obo/uberon/core#efo_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], "synonyms" : [ { "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003000", "pred" : "hasExactSynonym", "val" : "CNS" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "systema nervosum centrale", "xrefs" : [ "FMA:55675", "FMA:TA" ] @@ -24215,6 +24154,9 @@ "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099" + }, { + "pred" : "http://purl.obolibrary.org/obo/RO_0002175", + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" }, { "pred" : "http://purl.obolibrary.org/obo/UBPROP_0000001", "val" : "Part of the nervous system which includes the brain and spinal cord.[AAO]" @@ -24243,7 +24185,7 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#efo_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "organa sensuum", "xrefs" : [ "FMA:75259", "FMA:TA" ] @@ -24267,7 +24209,7 @@ "val" : "sensory systems", "xrefs" : [ "TAO:0000282" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "organa sensuum", "xrefs" : [ "Wikipedia:Sensory_system" ] @@ -24345,7 +24287,7 @@ "pred" : "hasRelatedSynonym", "val" : "presumptive central nervous system" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "tubus neuralis", "xrefs" : [ "Wikipedia:Neural_tube" ] @@ -24911,6 +24853,8 @@ "val" : "FMA:45615" }, { "val" : "MA:0000917" + }, { + "val" : "MESH:D041981" }, { "val" : "NCIT:C34082" }, { @@ -25393,7 +25337,7 @@ "val" : "notocord", "xrefs" : [ "ZFA:0000135" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "notochorda", "xrefs" : [ "Wikipedia:Notochord" ] @@ -25506,7 +25450,7 @@ "pred" : "hasRelatedSynonym", "val" : "somitic mesoderm" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "somitus", "xrefs" : [ "Wikipedia:Somite" ] @@ -25641,7 +25585,7 @@ "val" : "NC", "xrefs" : [ "XAO:0000048" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "crista neuralis", "xrefs" : [ "Wikipedia:Neural_crest" ] @@ -25735,7 +25679,7 @@ "pred" : "hasExactSynonym", "val" : "neuroectoderm" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "epithelium tubi neuralis; neuroectoderma", "xrefs" : [ "Wikipedia:Neuroectoderm" ] @@ -25818,7 +25762,7 @@ "val" : "ducted gland", "xrefs" : [ "AEO:0000097" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "glandula exocrina", "xrefs" : [ "Wikipedia:Exocrine_gland" ] @@ -25880,7 +25824,7 @@ "val" : "ductless gland", "xrefs" : [ "Wikipedia:Ductless_gland" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "glandulae endocrinae", "xrefs" : [ "Wikipedia:Endocrine_gland" ] @@ -25931,12 +25875,12 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#efo_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "medulla ossea", "xrefs" : [ "BTO:0000141", "FMA:9608" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "medulla ossium", "xrefs" : [ "BTO:0000141", "Wikipedia:Bone_marrow" ] @@ -26391,7 +26335,7 @@ "val" : "Druese", "xrefs" : [ "BTO:0000522" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "glandula", "xrefs" : [ "BTO:0000522", "Wikipedia:Gland" ] @@ -26477,7 +26421,7 @@ "val" : "ectoblast", "xrefs" : [ "MP:0003886" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "epiblastus", "xrefs" : [ "Wikipedia:Epiblast" ] @@ -26736,7 +26680,7 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "lamina neuralis", "xrefs" : [ "Wikipedia:Neural_plate" ] @@ -26814,7 +26758,7 @@ "val" : "somitic mesoderm", "xrefs" : [ "ISBN:9780878932504" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "mesoderma paraxiale", "xrefs" : [ "Wikipedia:Paraxial_mesoderm" ] @@ -26890,7 +26834,7 @@ "val" : "lateral plate mesenchyme", "xrefs" : [ "EHDAA2:0000919" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "mesoderma laminae lateralis", "xrefs" : [ "Wikipedia:Lateral_plate_mesoderm" ] @@ -26973,7 +26917,7 @@ "pred" : "hasRelatedSynonym", "val" : "myotomes" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "myotomus", "xrefs" : [ "Wikipedia:Myotome" ] @@ -27102,7 +27046,7 @@ "pred" : "hasExactSynonym", "val" : "portion of mesenchyme tissue" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "mesenchyma", "xrefs" : [ "Wikipedia:Mesenchyme" ] @@ -28159,7 +28103,7 @@ "val" : "basement membrane of connective tissue", "xrefs" : [ "FMA:63872" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "membrana basalis", "xrefs" : [ "Wikipedia:Basement_membrane" ] @@ -28908,7 +28852,7 @@ "val" : "A subdivision of an anatomical system.", "xrefs" : [ "http://orcid.org/0000-0002-6601-2165" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#common_anatomy", "http://purl.obolibrary.org/obo/uberon/core#upper_level" ], + "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#common_anatomy", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#upper_level" ], "xrefs" : [ { "val" : "FBbt:00007330" }, { @@ -28925,6 +28869,9 @@ }, { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_4751" + }, { + "pred" : "http://purl.obolibrary.org/obo/RO_0002175", + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "uberon" @@ -29257,7 +29204,7 @@ "val" : "The region of the organism associated with the visceral organs.", "xrefs" : [ "AEO:0000103" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#non_informative" ], + "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#non_informative" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "body", @@ -29277,9 +29224,6 @@ "val" : "FMA:231424" } ], "basicPropertyValues" : [ { - "pred" : "http://purl.obolibrary.org/obo/RO_0002175", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" - }, { "pred" : "http://purl.obolibrary.org/obo/UBPROP_0000001", "val" : "Cardinal body part, which consists of a maximal set of diverse subclasses of organ and organ part spatially associated with the vertebral column and ribcage. Examples: There is only one body proper[FMA:231424]." }, { @@ -29296,6 +29240,7 @@ "val" : "A muscle organ that consists of skeletal muscle tissue ensheathed in epimysium, that develops from myotome and that is innervated by some somatic motor neuron. Skeletal muscles are typically attached (via a tendon) to a bone but there are exceptions (e.g. intrinsic tongue muscles).", "xrefs" : [ "GOC:dos" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "skeletal muscle" @@ -29340,6 +29285,9 @@ "val" : "ZFA:0005277" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/RO_0002175", + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "uberon" } ] @@ -29567,7 +29515,7 @@ "lbl" : "skeletal musculature", "type" : "CLASS", "meta" : { - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#grouping_class" ], + "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#grouping_class", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { "val" : "EHDAA2:0001842" }, { @@ -29578,6 +29526,9 @@ "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000116", "val" : "Added for consistency with MA EMAPA and EHDAA2. See https://github.com/obophenotype/mouse-anatomy-ontology/issues/104" + }, { + "pred" : "http://purl.obolibrary.org/obo/RO_0002175", + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "uberon" @@ -29816,8 +29767,10 @@ "val" : "OBSOLETE A relation between a cell and molecule or complex such that every instance of the cell has a high number of instances of that molecule expressed on the cell surface. For the formal definition, see Masci et al (PMID:19243617).", "xrefs" : [ "PMID:19243617" ] }, - "comments" : [ "Replaced with RO:0015015, see https://github.com/obophenotype/cell-ontology/issues/1481" ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/obophenotype/cell-ontology/issues/1481" + }, { "pred" : "http://purl.obolibrary.org/obo/IAO_0100001", "val" : "http://purl.obolibrary.org/obo/RO_0015015" } ], @@ -29832,8 +29785,10 @@ "val" : "OBSOLETE A relation between a cell and molecule or complex such that every instance of the cell has a low number of instances of that molecule expressed on the cell surface. For the formal definition, see Masci et al (PMID:19243617).", "xrefs" : [ "PMID:19243617" ] }, - "comments" : [ "Replaced with RO:0015016, see https://github.com/obophenotype/cell-ontology/issues/1481" ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/obophenotype/cell-ontology/issues/1481" + }, { "pred" : "http://purl.obolibrary.org/obo/IAO_0100001", "val" : "http://purl.obolibrary.org/obo/RO_0015016" } ], @@ -30063,13 +30018,12 @@ "lbl" : "transitively anteriorly connected to", "type" : "PROPERTY", "meta" : { - "definition" : { - "val" : ".", - "xrefs" : [ "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" ] - }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "uberon" + }, { + "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", + "val" : "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" } ] } }, { @@ -30077,13 +30031,12 @@ "lbl" : "transitively distally connected to", "type" : "PROPERTY", "meta" : { - "definition" : { - "val" : ".", - "xrefs" : [ "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" ] - }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "uberon" + }, { + "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", + "val" : "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" } ] } }, { @@ -30091,13 +30044,12 @@ "lbl" : "transitively proximally connected to", "type" : "PROPERTY", "meta" : { - "definition" : { - "val" : ".", - "xrefs" : [ "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" ] - }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "uberon" + }, { + "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", + "val" : "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" } ] } }, { @@ -31294,11 +31246,11 @@ }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000542", "pred" : "http://purl.obolibrary.org/obo/BFO_0000051", - "obj" : "http://purl.obolibrary.org/obo/CL_0017505" + "obj" : "http://purl.obolibrary.org/obo/GO_0000792" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000542", - "pred" : "http://purl.obolibrary.org/obo/BFO_0000051", - "obj" : "http://purl.obolibrary.org/obo/GO_0000792" + "pred" : "http://purl.obolibrary.org/obo/RO_0000053", + "obj" : "http://purl.obolibrary.org/obo/PATO_0040072" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000542", "pred" : "http://purl.obolibrary.org/obo/RO_0002202", @@ -32221,14 +32173,6 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0017503", "pred" : "http://purl.obolibrary.org/obo/RO_0000053", "obj" : "http://purl.obolibrary.org/obo/PATO_0002094" - }, { - "sub" : "http://purl.obolibrary.org/obo/CL_0017505", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/GO_0005634" - }, { - "sub" : "http://purl.obolibrary.org/obo/CL_0017505", - "pred" : "http://purl.obolibrary.org/obo/RO_0000053", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000586" }, { "sub" : "http://purl.obolibrary.org/obo/CL_1001610", "pred" : "is_a", @@ -33678,7 +33622,7 @@ }, { "sub" : "http://purl.obolibrary.org/obo/GO_0045087", "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/GO_0098542" + "obj" : "http://purl.obolibrary.org/obo/GO_0140546" }, { "sub" : "http://purl.obolibrary.org/obo/GO_0045202", "pred" : "is_a", @@ -34427,6 +34371,10 @@ "sub" : "http://purl.obolibrary.org/obo/GO_0140352", "pred" : "http://purl.obolibrary.org/obo/RO_0002339", "obj" : "http://purl.obolibrary.org/obo/GO_0005576" + }, { + "sub" : "http://purl.obolibrary.org/obo/GO_0140546", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/GO_0098542" }, { "sub" : "http://purl.obolibrary.org/obo/GO_1901576", "pred" : "is_a", @@ -34615,18 +34563,6 @@ "sub" : "http://purl.obolibrary.org/obo/PATO_0000052", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/PATO_0000051" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0000068", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000001" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0000069", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000068" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0000117", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000051" }, { "sub" : "http://purl.obolibrary.org/obo/PATO_0000141", "pred" : "is_a", @@ -34635,18 +34571,6 @@ "sub" : "http://purl.obolibrary.org/obo/PATO_0000411", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/PATO_0000947" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0000461", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000068" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0000586", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000117" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0000586", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0002305" }, { "sub" : "http://purl.obolibrary.org/obo/PATO_0000947", "pred" : "is_a", @@ -34767,22 +34691,6 @@ "sub" : "http://purl.obolibrary.org/obo/PATO_0002299", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/PATO_0002078" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0002300", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000069" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0002300", - "pred" : "http://purl.obolibrary.org/obo/RO_0015007", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000461" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0002305", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0001241" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0002305", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0002300" }, { "sub" : "http://purl.obolibrary.org/obo/PATO_0002309", "pred" : "is_a", @@ -34807,6 +34715,10 @@ "sub" : "http://purl.obolibrary.org/obo/PATO_0015006", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/PATO_0000141" + }, { + "sub" : "http://purl.obolibrary.org/obo/PATO_0040072", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/PATO_0001396" }, { "sub" : "http://purl.obolibrary.org/obo/PATO_0070044", "pred" : "is_a", @@ -39846,15 +39758,15 @@ "restrictions" : [ { "propertyId" : "http://purl.obolibrary.org/obo/BFO_0000051", "fillerId" : "http://purl.obolibrary.org/obo/CL_0017500" - }, { - "propertyId" : "http://purl.obolibrary.org/obo/BFO_0000051", - "fillerId" : "http://purl.obolibrary.org/obo/CL_0017505" }, { "propertyId" : "http://purl.obolibrary.org/obo/BFO_0000051", "fillerId" : "http://purl.obolibrary.org/obo/GO_0000792" }, { "propertyId" : "http://purl.obolibrary.org/obo/RO_0000053", "fillerId" : "http://purl.obolibrary.org/obo/PATO_0001407" + }, { + "propertyId" : "http://purl.obolibrary.org/obo/RO_0000053", + "fillerId" : "http://purl.obolibrary.org/obo/PATO_0040072" } ] }, { "definedClassId" : "http://purl.obolibrary.org/obo/CL_0000557", @@ -40375,13 +40287,6 @@ "propertyId" : "http://purl.obolibrary.org/obo/RO_0000053", "fillerId" : "http://purl.obolibrary.org/obo/PATO_0002094" } ] - }, { - "definedClassId" : "http://purl.obolibrary.org/obo/CL_0017505", - "genusIds" : [ "http://purl.obolibrary.org/obo/GO_0005634" ], - "restrictions" : [ { - "propertyId" : "http://purl.obolibrary.org/obo/RO_0000053", - "fillerId" : "http://purl.obolibrary.org/obo/PATO_0000586" - } ] }, { "definedClassId" : "http://purl.obolibrary.org/obo/CL_1001610", "genusIds" : [ "http://purl.obolibrary.org/obo/CL_0000988" ], @@ -41223,27 +41128,6 @@ "propertyId" : "http://purl.obolibrary.org/obo/RO_0002211", "fillerId" : "http://purl.obolibrary.org/obo/GO_0007275" } ] - }, { - "definedClassId" : "http://purl.obolibrary.org/obo/PATO_0000586", - "genusIds" : [ "http://purl.obolibrary.org/obo/PATO_0000117" ], - "restrictions" : [ { - "propertyId" : "http://purl.obolibrary.org/obo/RO_0015007", - "fillerId" : "http://purl.obolibrary.org/obo/PATO_0000461" - } ] - }, { - "definedClassId" : "http://purl.obolibrary.org/obo/PATO_0002300", - "genusIds" : [ "http://purl.obolibrary.org/obo/PATO_0000001" ], - "restrictions" : [ { - "propertyId" : "http://purl.obolibrary.org/obo/RO_0015007", - "fillerId" : "http://purl.obolibrary.org/obo/PATO_0000461" - } ] - }, { - "definedClassId" : "http://purl.obolibrary.org/obo/PATO_0002305", - "genusIds" : [ "http://purl.obolibrary.org/obo/PATO_0001241" ], - "restrictions" : [ { - "propertyId" : "http://purl.obolibrary.org/obo/RO_0015007", - "fillerId" : "http://purl.obolibrary.org/obo/PATO_0000461" - } ] }, { "definedClassId" : "http://purl.obolibrary.org/obo/PR_000029032", "genusIds" : [ "http://purl.obolibrary.org/obo/PR_000000001" ], diff --git a/subsets/general_cell_types_upper_slim.obo b/subsets/general_cell_types_upper_slim.obo index 824b27a28..bf1c7bcd8 100644 --- a/subsets/general_cell_types_upper_slim.obo +++ b/subsets/general_cell_types_upper_slim.obo @@ -1,5 +1,5 @@ format-version: 1.2 -data-version: cl/releases/2024-01-04/subsets/general_cell_types_upper_slim.owl +data-version: cl/releases/2024-02-13/subsets/general_cell_types_upper_slim.owl subsetdef: abnormal_slim "" subsetdef: added_for_HCA "" subsetdef: attribute_slim "" @@ -31,6 +31,7 @@ subsetdef: goslim_mouse "" subsetdef: goslim_pir "" subsetdef: goslim_plant "" subsetdef: goslim_pombe "" +subsetdef: goslim_prokaryote "" subsetdef: goslim_synapse "" subsetdef: goslim_yeast "" subsetdef: grouping_class "" @@ -49,7 +50,6 @@ subsetdef: non_informative "" subsetdef: organ_slim "" subsetdef: pheno_slim "" subsetdef: phenotype_rcn "" -subsetdef: prokaryote_subset "" subsetdef: ro-eco "" subsetdef: RO:0002259 "" subsetdef: scalar_slim "" @@ -62,7 +62,6 @@ subsetdef: vertebrate_core "" synonymtypedef: blast_name "" synonymtypedef: COMPARATIVE_PREFERRED "" synonymtypedef: DEPRECATED "" -synonymtypedef: DUBIOUS "" synonymtypedef: equivalent_name "" synonymtypedef: genbank_common_name "" synonymtypedef: Gene-based "" @@ -71,13 +70,14 @@ synonymtypedef: HUMAN_PREFERRED "" synonymtypedef: HUMAN_PREFERRED "preferred term when talking about an instance of this class in Homo sapiens" synonymtypedef: in_part "" synonymtypedef: INCONSISTENT "" -synonymtypedef: LATIN "" synonymtypedef: LATIN "latin term" synonymtypedef: MISSPELLING "a mis-spelling that is in common use and thus recorded" synonymtypedef: NON_MAMMAL "" synonymtypedef: OMO:0003000 "abbreviation" +synonymtypedef: OMO:0003002 "" synonymtypedef: OMO:0003003 "" synonymtypedef: OMO:0003004 "plural form" +synonymtypedef: OMO:0003011 "" synonymtypedef: PENDING_REVIEW "" synonymtypedef: PLURAL "plural term" synonymtypedef: PRO-short-label "" @@ -88,7 +88,7 @@ synonymtypedef: synonym "" synonymtypedef: SYSTEMATIC "" synonymtypedef: systematic_synonym "" ontology: cl/subsets/general_cell_types_upper_slim -property_value: owl:versionInfo "2024-01-04" xsd:string +property_value: owl:versionInfo "2024-02-13" xsd:string [Term] id: BFO:0000002 @@ -144,6 +144,7 @@ id: CL:0000000 name: cell def: "A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane." [CARO:mah] comment: The definition of cell is intended to represent all cells, and thus a cell is defined as a material entity and not an anatomical structure, which implies that it is part of an organism (or the entirety of one). +subset: cellxgene_subset subset: ubprop:upper_level xref: CALOHA:TS-2035 xref: FBbt:00007002 @@ -163,6 +164,7 @@ relationship: only_in_taxon NCBITaxon:131567 ! cellular organisms [Term] id: CL:0000006 name: neuronal receptor cell +subset: cellxgene_subset synonym: "neuronal receptor cell (sensu Animalia)" EXACT [] is_a: CL:0000101 ! sensory neuron is_a: CL:0000197 ! sensory receptor cell @@ -181,6 +183,7 @@ id: CL:0000034 name: stem cell def: "A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells." [GOC:tfm, MESH:D013234] comment: This term applies to metazoan. For plant stem cells, consider using PO:0004011 ‘initial cell’ or its parent PO:0004010 ‘meristematic cell’. +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "animal stem cell" EXACT [] @@ -199,6 +202,7 @@ name: hematopoietic stem cell def: "A stem cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system. Hematopoietic stem cells lack cell markers of effector cells (lin-negative). Lin-negative is defined by lacking one or more of the following cell surface markers: CD2, CD3 epsilon, CD4, CD5 ,CD8 alpha chain, CD11b, CD14, CD19, CD20, CD56, ly6G, ter119." [GOC:add, GOC:dsd, GOC:tfm, http://en.wikipedia.org/wiki/Hematopoietic_stem_cell, PMID:19022770] comment: Markers differ between species, and two sets of markers have been described for mice. HSCs are reportedly CD34-positive, CD45-positive, CD48-negative, CD150-positive, CD133-positive, and CD244-negative. subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "blood forming stem cell" EXACT [] synonym: "colony forming unit hematopoietic" RELATED [] @@ -299,6 +303,7 @@ id: CL:0000049 name: common myeloid progenitor def: "A progenitor cell committed to myeloid lineage, including the megakaryocyte and erythroid lineages." [GOC:add, ISBN:0878932437, MESH:D023461] comment: This cell type is intended to be compatible with any vertebrate common myeloid progenitor. For mammalian CMP known to be CD34-positive, please use the term 'common myeloid progenitor, CD34-positive' (CL_0001059). +subset: cellxgene_subset subset: human_reference_atlas synonym: "CFU-GEMM" RELATED OMO:0003000 [ISBN:0878932437] synonym: "CFU-S" RELATED OMO:0003000 [ISBN:0878932437] @@ -319,6 +324,7 @@ id: CL:0000051 name: common lymphoid progenitor def: "A oligopotent progenitor cell committed to the lymphoid lineage." [GOC:add, GOC:dsd, GOC:tfm, PMID:10407577, PMID:16551251] comment: CLP are CD7-positive, CD10-positive, CD19-negative, CD34-positive, CD45RA-positive, CD79a-negative, CD127-positive, AA4.1-positive, RAG-negative, Sca-1-low, sIgM-negative, sIgD-negative, TdT-negative, Vpre-B-negative, and pre-BCR-negative. Expression of transcription factors include E2A-positive, EBF-positive, Ikaros-negative, PU.1-negative, and Pax5-negative. +subset: cellxgene_subset subset: human_reference_atlas synonym: "CLP" RELATED OMO:0003000 [] synonym: "committed lymphopoietic stem cell" RELATED [] @@ -350,6 +356,7 @@ id: CL:0000055 name: non-terminally differentiated cell def: "A precursor cell with a limited number of potential fates." [SANBI:mhl] comment: define using PATO mulit-potent or oligopotent? +subset: cellxgene_subset synonym: "blast cell" EXACT [] xref: BTO:0000125 xref: FMA:84782 @@ -371,6 +378,7 @@ id: CL:0000057 name: fibroblast def: "A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped." [http://en.wikipedia.org/wiki/Fibroblast, ISBN:0517223651, MESH:D005347] comment: These cells may be vimentin-positive, fibronectin-positive, fsp1-positive, MMP-1-positive, collagen I-positive, collagen III-positive, and alpha-SMA-negative. +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas xref: BTO:0000452 @@ -386,6 +394,7 @@ relationship: present_in_taxon NCBITaxon:9606 id: CL:0000066 name: epithelial cell def: "A cell that is usually found in a two-dimensional sheet with a free surface. The cell has a cytoskeleton that allows for tight cell to cell contact and for cell polarity where apical part is directed towards the lumen and the basal part to the basal lamina." [FB:ma, GOC:tfm, MESH:D004847] +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "epitheliocyte" EXACT [] @@ -405,6 +414,7 @@ property_value: depiction "https://www.swissbiopics.org/api/image/Epithelial_cel id: CL:0000075 name: columnar/cuboidal epithelial cell def: "A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube." [GO:0002065, https://orcid.org/0000-0001-5208-3432] +subset: cellxgene_subset subset: human_reference_atlas is_a: CL:0000066 ! epithelial cell relationship: present_in_taxon NCBITaxon:9606 @@ -413,6 +423,7 @@ relationship: present_in_taxon NCBITaxon:9606 id: CL:0000081 name: blood cell def: "A cell found predominately in the blood." [GOC:add, GOC:tfm] +subset: cellxgene_subset subset: general_cell_types_upper_slim xref: FMA:62844 xref: MESH:D001773 @@ -425,6 +436,7 @@ relationship: capable_of GO:0008015 ! blood circulation id: CL:0000084 name: T cell def: "A type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex." [GOC:add, GOC:tfm, ISBN:0781735149] +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "immature T cell" RELATED [] @@ -450,6 +462,7 @@ id: CL:0000092 name: osteoclast def: "A specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue, which typically differentiates from monocytes. This cell has the following markers: tartrate-resistant acid phosphatase type 5-positive, PU.1-positive, c-fos-positive, nuclear factor NF-kappa-B p100 subunit-positive, tumor necrosis factor receptor superfamily member 11A-positive and macrophage colony-stimulating factor 1 receptor-positive." [GO_REF:0000031, GOC:add, GOC:tfm, ISBN:0781735149, PMID:10428500, PMID:15055519, PMID:17380158] comment: Morphology: Highly vesicular; markers: Surface: RANK, cFMS (MCSF receptor); Secreted: cathepsin K and TRAP (tartate resistant acid phosphatase); transcription factors: PU.1, cFOS, MITF, NFkB (p52); role or process: tissue remodelling: bone resorption; lineage: hematopoietic, myeloid. +subset: cellxgene_subset synonym: "chondroclast" RELATED [] xref: BTO:0000968 xref: CALOHA:TS-0721 @@ -483,6 +496,7 @@ relationship: RO:0002104 PR:000002062 ! has plasma membrane part macrophage colo id: CL:0000094 name: granulocyte def: "A leukocyte with abundant granules in the cytoplasm." [GOC:amm, GOC:tfm, http://en.wikipedia.org/wiki/Granulocyte, MESH:D006098] +subset: cellxgene_subset subset: human_reference_atlas synonym: "granular leucocyte" EXACT [] synonym: "granular leukocyte" EXACT [] @@ -517,6 +531,7 @@ relationship: RO:0002104 PR:000001969 ! has plasma membrane part urokinase plasm [Term] id: CL:0000095 name: neuron associated cell +subset: cellxgene_subset is_a: CL:0002319 ! neural cell relationship: develops_from CL:0000133 ! neurectodermal cell @@ -524,6 +539,7 @@ relationship: develops_from CL:0000133 ! neurectodermal cell id: CL:0000100 name: motor neuron def: "An efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes or inhibits movement." [MESH:D009046, PMID:16875686] +subset: cellxgene_subset subset: human_reference_atlas synonym: "motoneuron" EXACT [] xref: BTO:0000312 @@ -551,6 +567,7 @@ relationship: capable_of GO:0050906 ! detection of stimulus involved in sensory id: CL:0000113 name: mononuclear phagocyte def: "A vertebrate phagocyte with a single nucleus." [GOC:add, GOC:tfm, ISBN:0781735149] +subset: cellxgene_subset subset: human_reference_atlas xref: BTO:0001433 is_a: CL:0000518 {is_inferred="true"} ! phagocyte (sensu Vertebrata) @@ -564,6 +581,7 @@ id: CL:0000125 name: glial cell def: "A non-neuronal cell of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu. Guide neuronal migration during development, and exchange metabolites with neurons." [MESH:D009457] comment: Not all glial cells develop from glioblasts, with microglia developing from the mesoderm instead. See https://github.com/obophenotype/cell-ontology/issues/1571 +subset: cellxgene_subset subset: general_cell_types_upper_slim synonym: "neuroglia" RELATED [] synonym: "neuroglial cell" EXACT [] @@ -585,6 +603,7 @@ id: CL:0000134 name: mesenchymal stem cell def: "A connective tissue cell that normally gives rise to other cells that are organized as three-dimensional masses. In humans, this cell type is CD73-positive, CD90-positive, CD105-positive, CD45-negative, CD34-negative, and MHCII-negative. They may further differentiate into osteoblasts, adipocytes, myocytes, neurons, or chondroblasts in vitro. Originally described as residing in the bone marrow, this cell type is now known to reside in many, if not all, adult organs." [FB:ma, GOC:dsd, http://en.wikipedia.org/wiki/Mesenchymal_stem_cell, http://www.copewithcytokines.de/cope.cgi?key=mesenchymal%20stem%20cells, PMCID:PMC2613570, PMID:10102814, PMID:16923606, PMID:17986482, PMID:19960544] comment: Many but not all mesenchymal cells derive from the mesoderm. MSCs are reportedly CD3-negative, CD4-negative, CD5-negative, CD8-negative, CD11a-negative, CD11b-negative, CD14-negative, CD19-negative, CD29-positive, CD31-negative, CD34-negative, CD38-negative, CD40-negative, CD44-positive, CD45-negative, CD49-positive, CD54-positive, CD66b-negative, CD79a-negative, CD80-negative, CD102-positive, CD106-positive, CD117-positive, CD121a-positive, CD121b-positive, CD123-positive, CD124-positive, CD133-negative, CD146-positive, CD166-positive, CD271-positive, B220-negative, Gr1-negative, MHCI-positive, MHCII-negative, SSEA4-negative, sca1-positive, Ter119-negative, and glycophorin A-negative. Cultured MSCs are capable of producing stem cell factor, IL7, IL8, IL11, TGF-beta, cofilin, galectin-1, laminin-receptor 1, cyclophilin A, and MMP-2. +subset: cellxgene_subset synonym: "BMSC" RELATED OMO:0003000 [] synonym: "bone marrow stromal cells" NARROW [] synonym: "CFU-F" RELATED OMO:0003000 [] @@ -608,6 +627,7 @@ property_value: seeAlso "https://github.com/obophenotype/cell-ontology/issues/47 id: CL:0000136 name: adipocyte def: "A fat-storing cell found mostly in the abdominal cavity and subcutaneous tissue of mammals. Fat is usually stored in the form of triglycerides." [MESH:D017667] +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "adipose cell" EXACT [] @@ -626,6 +646,7 @@ name: professional antigen presenting cell def: "A cell capable of processing and presenting lipid and protein antigens to T cells in order to initiate an immune response." [GOC:add, ISBN:0781735149] comment: Note change of name; nearly all somatic cells can present antigens to T cells via MHC Class I complexes leading to effector responses, but professional antigen presenting cells constitutively express MHC Class II as well as costimulatory molecules, and thus can initiate immune responses via T cells. subset: blood_and_immune_upper_slim +subset: cellxgene_subset synonym: "APC" RELATED OMO:0003000 [] is_a: CL:0000738 ! leukocyte intersection_of: CL:0000738 ! leukocyte @@ -645,6 +666,7 @@ is_a: CL:0000325 ! stuff accumulating cell id: CL:0000148 name: melanocyte def: "A pigment cell derived from the neural crest. Contains melanin-filled pigment granules, which gives a brown to black appearance." [SANBI:mhl] +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "melanophore" NARROW [] @@ -671,6 +693,7 @@ is_a: CL:0000147 ! pigment cell id: CL:0000151 name: secretory cell def: "A cell that specializes in controlled release of one or more substances." [GOC:tfm, ISBN:0721662544] +subset: cellxgene_subset xref: BTO:0003659 xref: FMA:86916 is_a: CL:0000000 ! cell @@ -693,6 +716,7 @@ relationship: part_of UBERON:0002365 ! exocrine gland id: CL:0000163 name: endocrine cell def: "A cell of an endocrine gland, ductless glands that secrete substances which are released directly into the circulation and which influence metabolism and other body functions." [MESH:D055098] +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "endocrinocyte" EXACT [] @@ -705,12 +729,14 @@ relationship: present_in_taxon NCBITaxon:9606 id: CL:0000183 name: contractile cell def: "A cell whose primary function is to shorten." [FB:ma] +subset: cellxgene_subset is_a: CL:0000000 ! cell [Term] id: CL:0000187 name: muscle cell def: "A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns." [MESH:D032342] +subset: cellxgene_subset synonym: "muscle fiber" EXACT [] synonym: "myocyte" EXACT [] xref: BTO:0000888 @@ -728,6 +754,7 @@ property_value: depiction "https://www.swissbiopics.org/api/image/Muscle_cells.s id: CL:0000188 name: cell of skeletal muscle def: "A somatic cell located in skeletal muscle." [GOC:tfm] +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "skeletal muscle cell" EXACT [] @@ -744,6 +771,7 @@ relationship: present_in_taxon NCBITaxon:9606 id: CL:0000192 name: smooth muscle cell def: "A non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels. They develop from specialized myoblasts (smooth muscle myoblast)." [http://en.wikipedia.org/wiki/Smooth_muscle_cell, MESH:D032389, PMID:9315361] +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "myocytes, smooth muscle" EXACT [MESH:D032389] @@ -775,6 +803,7 @@ relationship: part_of UBERON:0001032 ! sensory system id: CL:0000210 name: photoreceptor cell def: "A cell specialized to detect and transduce light." [MESH:D010786] +subset: cellxgene_subset xref: BTO:0001060 xref: CALOHA:TS-0868 xref: FMA:86740 @@ -812,6 +841,7 @@ relationship: part_of UBERON:0000924 ! ectoderm id: CL:0000222 name: mesodermal cell def: "A cell of the middle germ layer of the embryo." [MESH:D008648] +subset: cellxgene_subset synonym: "mesoblast" EXACT [] synonym: "mesoderm cell" EXACT [] xref: FMA:72554 @@ -854,6 +884,7 @@ relationship: bearer_of PATO:0001908 ! multinucleate id: CL:0000234 name: phagocyte def: "Any cell capable of ingesting particulate matter via phagocytosis." [GOC:add, ISBN:0721601464] +subset: cellxgene_subset xref: BTO:0001044 xref: FMA:83806 xref: MESH:D010586 @@ -870,6 +901,7 @@ name: macrophage def: "A mononuclear phagocyte present in variety of tissues, typically differentiated from monocytes, capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells." [GO_REF:0000031, GOC:add, GOC:tfm, PMID:16213494, PMID:1919437] comment: Morphology: Diameter 30_M-80 _M, abundant cytoplasm, low N/C ratio, eccentric nucleus. Irregular shape with pseudopods, highly adhesive. Contain vacuoles and phagosomes, may contain azurophilic granules; markers: Mouse & Human: CD68, in most cases CD11b. Mouse: in most cases F4/80+; role or process: immune, antigen presentation, & tissue remodelling; lineage: hematopoietic, myeloid. subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "histiocyte" EXACT [] @@ -894,6 +926,7 @@ id: CL:0000236 name: B cell def: "A lymphocyte of B lineage that is capable of B cell mediated immunity." [GO_REF:0000031, GOC:add, GOC:tfm, ISBN:0781735149] subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "B lymphocyte" EXACT [] @@ -913,6 +946,7 @@ relationship: present_in_taxon NCBITaxon:9606 [Term] id: CL:0000255 name: eukaryotic cell +subset: cellxgene_subset xref: MESH:D005057 is_a: CL:0000000 ! cell intersection_of: CL:0000000 ! cell @@ -998,6 +1032,7 @@ is_a: CL:0000211 ! electrically active cell id: CL:0000451 name: dendritic cell def: "A cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation. These cells are lineage negative (CD3-negative, CD19-negative, CD34-negative, and CD56-negative)." [GOC:add, ISBN:0781735149] +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "interdigitating cell" RELATED [] @@ -1042,6 +1077,7 @@ is_a: CL:0000000 ! cell id: CL:0000499 name: stromal cell def: "A connective tissue cell of an organ found in the loose connective tissue. These are most often associated with the uterine mucosa and the ovary as well as the hematopoietic system and elsewhere." [GOC:tfm, MESH:D017154] +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas xref: BTO:0002064 @@ -1054,27 +1090,29 @@ relationship: present_in_taxon NCBITaxon:9606 id: CL:0000513 name: cardiac muscle myoblast def: "A precursor cell destined to differentiate into cardiac muscle cell." [GOC:tfm, MESH:D032386] +subset: cellxgene_subset synonym: "cardiac muscle progenitor cell" EXACT [] synonym: "cardiomyocyte progenitor cell" EXACT [] xref: FMA:84797 is_a: CL:0002494 ! cardiocyte is_a: CL:0010021 ! cardiac myoblast intersection_of: CL:0000056 ! myoblast +intersection_of: develops_into CL:0000746 ! cardiac muscle cell intersection_of: part_of UBERON:0001133 ! cardiac muscle tissue -intersection_of: RO:0002203 CL:0000746 ! develops into cardiac muscle cell relationship: part_of UBERON:0001133 ! cardiac muscle tissue [Term] id: CL:0000514 name: smooth muscle myoblast def: "A precursor cell destined to differentiate into smooth muscle myocytes." [GOC:tfm, MESH:D032390] +subset: cellxgene_subset synonym: "myoblast, smooth muscle" EXACT [MESH:D032390] synonym: "satellite cell" RELATED [] xref: FMA:84798 is_a: CL:0000056 ! myoblast intersection_of: CL:0000056 ! myoblast -intersection_of: RO:0002203 CL:0000192 ! develops into smooth muscle cell -relationship: RO:0002203 CL:0000192 ! develops into smooth muscle cell +intersection_of: develops_into CL:0000192 ! smooth muscle cell +relationship: develops_into CL:0000192 ! smooth muscle cell [Term] id: CL:0000515 @@ -1085,9 +1123,9 @@ xref: FMA:84799 is_a: CL:0000056 ! myoblast is_a: CL:0011026 ! progenitor cell intersection_of: CL:0000056 ! myoblast -intersection_of: RO:0002203 CL:0008002 ! develops into skeletal muscle fiber +intersection_of: develops_into CL:0008002 ! skeletal muscle fiber relationship: develops_from CL:0000355 ! multi-potent skeletal muscle stem cell -relationship: RO:0002203 CL:0008002 ! develops into skeletal muscle fiber +relationship: develops_into CL:0008002 ! skeletal muscle fiber [Term] id: CL:0000518 @@ -1119,6 +1157,7 @@ id: CL:0000540 name: neuron def: "The basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system." [http://en.wikipedia.org/wiki/Neuron, MESH:D009474] comment: These cells are also reportedly CD4-negative and CD200-positive. They are also capable of producing CD40L and IFN-gamma. +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "nerve cell" EXACT [] @@ -1151,6 +1190,7 @@ id: CL:0000542 name: lymphocyte def: "A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin." [GOC:add, ISBN:0683073696, ISBN:0781735149] comment: Editors note: consider adding taxon constraint to vertebrata (PMID:18025161) +subset: cellxgene_subset subset: human_reference_atlas xref: BTO:0000775 xref: CALOHA:TS-0583 @@ -1161,13 +1201,13 @@ is_a: CL:0000842 ! mononuclear cell is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000738 ! leukocyte intersection_of: bearer_of PATO:0001407 ! mononucleate +intersection_of: bearer_of PATO:0040072 ! high nuclear/cytoplasmic ratio intersection_of: has_part CL:0017500 ! neutrophillic cytoplasm -intersection_of: has_part CL:0017505 ! increased nucleus size intersection_of: has_part GO:0000792 ! heterochromatin disjoint_from: CL:0000766 ! myeloid leukocyte +relationship: bearer_of PATO:0040072 ! high nuclear/cytoplasmic ratio relationship: develops_from CL:0000051 ! common lymphoid progenitor relationship: has_part CL:0017500 ! neutrophillic cytoplasm -relationship: has_part CL:0017505 ! increased nucleus size relationship: has_part GO:0000792 ! heterochromatin relationship: present_in_taxon NCBITaxon:9606 @@ -1176,6 +1216,7 @@ id: CL:0000557 name: granulocyte monocyte progenitor cell def: "A hematopoietic progenitor cell that is committed to the granulocyte and monocyte lineages. These cells are CD123-positive, and do not express Gata1 or Gata2 but do express C/EBPa, and Pu.1." [GO_REF:0000031, GOC:amm, GOC:dsd, GOC:tfm, http://en.wikipedia.org/wiki/CFU-GM, http://www.copewithcytokines.de, ISBN:0721601464, MESH:D055014, PMCID:PMC2213186, PMCID:PMC548021, PMID:16551251, PMID:16647566] comment: Originally described in the dendritic cell ontology (DC_CL:0000042)(PMID:19243617). GMPs are reportedly CD16-positive, CD32-positive, CD34-positive, CD38-positive, CD45RA-positive, CD110-negative, CD117-positive, CD123-positive, and SCA1-negative. +subset: cellxgene_subset subset: human_reference_atlas synonym: "CFU-C , Colony forming unit in culture" BROAD [http://www.copewithcytokines.de] synonym: "CFU-GM" RELATED OMO:0003000 [ISBN:0721601464, PMCID:PMC2213186, PMCID:PMC548021] @@ -1212,6 +1253,7 @@ id: CL:0000559 name: promonocyte def: "A precursor in the monocytic series, being a cell intermediate in development between the monoblast and monocyte. This cell is CD11b-positive and has fine azurophil granules." [GOC:tfm, ISBN:0721601464] comment: Morphology: Mononuclear cell, diameter 14-18 _M, fine azurophilic granules; markers: CD11b (shared with many other myeloid cells); location: Adult: bone marrow; Fetal: Liver, Yolk Sac; role or process: hematopoiesis, monocyte development; lineage: hematopoietic, myeloid. +subset: cellxgene_subset subset: human_reference_atlas xref: BTO:0004657 xref: FMA:83551 @@ -1252,6 +1294,7 @@ name: monocyte def: "Myeloid mononuclear recirculating leukocyte that can act as a precursor of tissue macrophages, osteoclasts and some populations of tissue dendritic cells." [GO_REF:0000031, MESH:D009000] comment: Morphology: Mononuclear cell, diameter, 14 to 20 _M, N/C ratio 2:1-1:1. Nucleus may appear in variety of shapes: round, kidney, lobulated, or convoluted. Fine azurophilic granules present; markers: CD11b (shared with other myeloid cells), human: CD14, mouse: F4/80-mid,GR1-low; location: Blood, but can be recruited into tissues; role or process: immune & tissue remodelling; lineage: hematopoietic, myeloid. subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas xref: BTO:0000876 @@ -1275,6 +1318,7 @@ relationship: present_in_taxon NCBITaxon:9606 id: CL:0000623 name: natural killer cell def: "A lymphocyte that can spontaneously kill a variety of target cells without prior antigenic activation via germline encoded activation receptors and also regulate immune responses via cytokine release and direct contact with other cells." [GOC:add, ISBN:0781735149, PMID:15771571] +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "large granular lymphocyte" BROAD [] @@ -1306,11 +1350,12 @@ relationship: present_in_taxon NCBITaxon:9606 id: CL:0000680 name: muscle precursor cell def: "A non-terminally differentiated cell that is capable of developing into a muscle cell." [GOC:add] +subset: cellxgene_subset is_a: CL:0000055 ! non-terminally differentiated cell intersection_of: CL:0011115 ! precursor cell -intersection_of: RO:0002203 CL:0000187 ! develops into muscle cell +intersection_of: develops_into CL:0000187 ! muscle cell relationship: develops_from CL:0000222 ! mesodermal cell -relationship: RO:0002203 CL:0000187 ! develops into muscle cell +relationship: develops_into CL:0000187 ! muscle cell [Term] id: CL:0000723 @@ -1342,6 +1387,7 @@ relationship: has_part GO:0030017 ! sarcomere id: CL:0000738 name: leukocyte def: "An achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue." [GOC:add, GOC:tfm, ISBN:978-0-323-05290-0] +subset: cellxgene_subset subset: human_reference_atlas synonym: "immune cell" RELATED [] synonym: "leucocyte" EXACT [] @@ -1370,6 +1416,7 @@ name: cardiac muscle cell alt_id: FMA:83808 def: "Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. In mammals, the contractile fiber resembles those of skeletal muscle but are only one third as large in diameter, are richer in sarcoplasm, and contain centrally located instead of peripheral nuclei." [GOC:mtg_cardiacconduct_nov11, GOC:tfm, ISBN:0323052908, PMID:22426062, PMID:4711263] comment: This class encompasses the muscle cells responsible for heart* contraction in both vertebrates and arthropods. The ultrastucture of a wide range of arthropod heart cells has been examined including spiders, horseshoe crabs, crustaceans (see Sherman, 1973 and refs therein) and insects (see Lehmacher et al (2012) and refs therein). According to these refs, the cells participating in heart contraction in all cases are transversely striated. Insects hearts additionally contain ostial cells, also transversely striated muscle cells, but which do not participate in heart contraction. +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "cardiac muscle fiber" EXACT [GO:0048739] @@ -1397,6 +1444,7 @@ relationship: present_in_taxon NCBITaxon:9606 id: CL:0000763 name: myeloid cell def: "A cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage." [GOC:add] +subset: cellxgene_subset xref: BTO:0001441 xref: CALOHA:TS-0647 xref: MESH:D022423 @@ -1409,6 +1457,7 @@ relationship: develops_from CL:0000049 ! common myeloid progenitor id: CL:0000766 name: myeloid leukocyte def: "A cell of the monocyte, granulocyte, or mast cell lineage." [GOC:add] +subset: cellxgene_subset is_a: CL:0000738 {is_inferred="true"} ! leukocyte is_a: CL:0000763 ! myeloid cell intersection_of: CL:0000738 ! leukocyte @@ -1419,6 +1468,7 @@ id: CL:0000775 name: neutrophil def: "Any of the immature or mature forms of a granular leukocyte that in its mature form has a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes." [GOC:add, GOC:amm, GOC:tfm, ISBN:0721601464] subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "neutrocyte" EXACT [] synonym: "neutrophil leucocyte" EXACT [] @@ -1449,6 +1499,7 @@ id: CL:0000782 name: myeloid dendritic cell def: "A dendritic cell of the myeloid lineage." [GOC:add, PMID:10449155, PMID:17332250, PMID:9521319] comment: These cells are CD1a-negative, CD1b-positive, CD11a-positive, CD11c-positive, CD13-positive, CD14-negative, CD20-negative, CD21-negative, CD33-positive, CD40-negative, CD50-positive, CD54-positive, CD58-positive, CD68-negative, CD80-negative, CD83-negative, CD85j-positive, CD86-positive, CD89-negative, CD95-positive, CD120a-negative, CD120b-positive, CD123-negative, CD178-negative, CD206-negative, CD207-negative, CD209-negative, and TNF-alpha-negative. Upon TLR stimulation, they are capable of producing high levels of TNF-alpha, IL-6, CXCL8 (IL-8). +subset: cellxgene_subset synonym: "CD11c+CD123- DC" EXACT [] synonym: "interdigitating cell" BROAD [] synonym: "mDC" EXACT [] @@ -1494,6 +1545,7 @@ id: CL:0000826 name: pro-B cell def: "A progenitor cell of the B cell lineage, with some lineage specific activity such as early stages of recombination of B cell receptor genes, but not yet fully committed to the B cell lineage until the expression of PAX5 occurs." [GOC:add, GOC:dsd, ISBN:0781735149, PMID:12633665, PMID:16551251, PMID:18432934] comment: Human pro-B cells are reportedly CD10-positive, CD22-positive, CD34-positive, CD38-positive, CD45-low, CD48-positive, CD79a-positive, CD127-positive, CD184-positive, RAG-positive, TdT-positive, Vpre-B-positive, pre-BCR-negative, IgD-negative, and IgM-negative. Transcription factors expressed: Pax5-positive, EBF-positive, E2A-negative, Ikaros-negative, and PU.1-negative. +subset: cellxgene_subset subset: human_reference_atlas synonym: "pre-B cell (Philadelphia nomenclature)" RELATED [PMID:11244048] synonym: "pre-pro B cell" BROAD [PMID:17582343] @@ -1521,6 +1573,7 @@ relationship: present_in_taxon NCBITaxon:9606 id: CL:0000827 name: pro-T cell def: "A lymphoid progenitor cell of the T cell lineage, with some lineage specific marker expression, but not yet fully committed to the T cell lineage." [GOC:add, ISBN:0781735149] +subset: cellxgene_subset synonym: "DN1 cell" NARROW [] synonym: "DN1 thymocyte" NARROW [] synonym: "pro-T lymphocyte" EXACT [] @@ -1538,6 +1591,7 @@ name: hematopoietic multipotent progenitor cell def: "A hematopoietic multipotent progenitor cell is multipotent, but not capable of long-term self-renewal. These cells are characterized as lacking lineage cell surface markers and being CD34-positive in both mice and humans." [GOC:add, GOC:tfm, PMID:19022770] comment: Markers differ between mouse and human. subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "hemopoietic progenitor cell" EXACT [] synonym: "MPP" EXACT [] @@ -1585,6 +1639,7 @@ id: CL:0000838 name: lymphoid lineage restricted progenitor cell def: "A progenitor cell restricted to the lymphoid lineage." [GOC:add, GOC:tfm] comment: Note that this is a class of cell types, not an identified single cell type. +subset: cellxgene_subset synonym: "lymphoid progenitor cell" BROAD [] xref: BTO:0004731 xref: CALOHA:TS-2025 @@ -1601,6 +1656,7 @@ id: CL:0000839 name: myeloid lineage restricted progenitor cell def: "A progenitor cell restricted to the myeloid lineage." [GOC:add, GOC:tfm, PMID:19022770] comment: Note that this is a class of cell types, not an identified single cell type. +subset: cellxgene_subset subset: human_reference_atlas synonym: "myeloid progenitor cell" BROAD [] xref: BTO:0004730 @@ -1618,6 +1674,7 @@ id: CL:0000842 name: mononuclear cell def: "A leukocyte with a single non-segmented nucleus in the mature form." [GOC:add] subset: blood_and_immune_upper_slim +subset: cellxgene_subset synonym: "mononuclear leukocyte" EXACT [] synonym: "peripheral blood mononuclear cell" NARROW [] xref: BTO:0000878 @@ -1642,6 +1699,7 @@ relationship: present_in_taxon NCBITaxon:9606 id: CL:0000988 name: hematopoietic cell def: "A cell of a hematopoietic lineage." [GO_REF:0000031, GOC:add] +subset: cellxgene_subset synonym: "haematopoietic cell" EXACT [] synonym: "haemopoietic cell" EXACT [] synonym: "hemopoietic cell" EXACT [] @@ -1657,6 +1715,7 @@ name: conventional dendritic cell def: "Conventional dendritic cell is a dendritic cell that is CD11c-high." [GO_REF:0000031, GOC:amm, PMID:17850486] comment: Originally described in the dendritic cell ontology (DC_CL:0000003)(PMID:19243617) These cells are also CD20-negative, MHCII-positive. subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "cDC" EXACT [] synonym: "DC1" EXACT [] @@ -1730,6 +1789,7 @@ id: CL:0001065 name: innate lymphoid cell def: "A lymphocyte that lacks characteristic T cell, B cell, myeloid cell, and dendritic cell markers, that functions as part of the innate immune response to produce cytokines and other effector responses." [GOC:add, GOC:dsd, PMID:23292121, PMID:23348417] subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas is_a: CL:0000542 ! lymphocyte intersection_of: CL:0000542 ! lymphocyte @@ -1762,6 +1822,7 @@ property_value: dcterms-date "2017-01-30T20:42:44Z" xsd:dateTime id: CL:0002009 name: macrophage dendritic cell progenitor def: "A progenitor cell that can give rise to plasmacytoid and myeloid dendritic cells, and to monocytes and macrophages." [GOC:tfm, PMID:19273628] +subset: cellxgene_subset synonym: "MDP" EXACT [] is_a: CL:0000763 ! myeloid cell is_a: CL:0002032 {is_inferred="true"} ! hematopoietic oligopotent progenitor cell @@ -1820,6 +1881,7 @@ id: CL:0002092 name: bone marrow cell def: "A cell found in the bone marrow. This can include fibroblasts, macrophages, adipocytes, osteoblasts, osteoclasts, endothelial cells and hematopoietic cells." [GOC:tfm, ISBN:0618947256] comment: MH consider whether bone marrow cells are bone cells in the structural sense vs. being part of bone organ sense. +subset: cellxgene_subset xref: BTO:0004850 xref: FMA:83621 xref: MESH:D001854 @@ -1858,6 +1920,7 @@ creation_date: 2010-09-07T03:32:33Z id: CL:0002319 name: neural cell def: "A cell that is part of the nervous system." [GOC:tfm, ISBN:0618947256] +subset: cellxgene_subset xref: CALOHA:TS-2040 xref: FMA:70333 is_a: CL:0000000 ! cell @@ -1871,6 +1934,7 @@ creation_date: 2010-09-15T01:34:57Z id: CL:0002320 name: connective tissue cell def: "A cell of the supporting or framework tissue of the body, arising chiefly from the embryonic mesoderm and including adipose tissue, cartilage, and bone." [GOC:tfm, ISBN:0618947256] +subset: cellxgene_subset xref: CALOHA:TS-2096 xref: FMA:63875 xref: MESH:D003239 @@ -1956,12 +2020,14 @@ is_a: CL:0000187 ! muscle cell id: CL:0008001 name: hematopoietic precursor cell def: "Any hematopoietic cell that is a precursor of some other hematopoietic cell type." [GOC:dos] +subset: cellxgene_subset is_a: CL:0000988 ! hematopoietic cell [Term] id: CL:0008002 name: skeletal muscle fiber def: "A transversely striated, synctial cell of skeletal muscle. It is formed when proliferating myoblasts exit the cell cycle, differentiate and fuse." [GOC:tfm, ISBN:0323052908] +subset: cellxgene_subset xref: MESH:D018485 is_a: CL:0000188 ! cell of skeletal muscle is_a: CL:0002372 ! myotube @@ -1986,6 +2052,7 @@ relationship: part_of UBERON:8600004 ! visceral muscle tissue id: CL:0008019 name: mesenchymal cell def: "A non-polarised cell precursor cell that is part of some mesenchyme, is associated with the cell matrix but is not connected to other cells and is capable of migration." [] +subset: cellxgene_subset subset: human_reference_atlas synonym: "mesenchyme cell" EXACT [] is_a: CL:0000219 ! motile cell @@ -2018,13 +2085,14 @@ name: cardiac myoblast xref: MESH:D032386 is_a: CL:0000056 ! myoblast intersection_of: CL:0000056 ! myoblast -intersection_of: RO:0002203 CL:0000746 ! develops into cardiac muscle cell -relationship: RO:0002203 CL:0000746 ! develops into cardiac muscle cell +intersection_of: develops_into CL:0000746 ! cardiac muscle cell +relationship: develops_into CL:0000746 ! cardiac muscle cell [Term] id: CL:0011012 name: neural crest cell def: "A cell of the neural crest. Neural crest cells are multipotent. Premigratory neural crest cells are found at the neural plate boarder, some of which will undergo ectomesynchymal transition and delamination to form migratory neural crest cells." [https://orcid.org/0000-0001-5208-3432, https://orcid.org/0000-0002-9900-7880] +subset: cellxgene_subset is_a: CL:0000048 ! multi fate stem cell is_a: CL:0002321 ! embryonic cell (metazoa) @@ -2032,6 +2100,7 @@ is_a: CL:0002321 ! embryonic cell (metazoa) id: CL:0011026 name: progenitor cell def: "A precursor cell that has a tendency to differentiate into a specific type of cell. They are descendants of stem cells, only they are more constrained in their differentiation potential or capacity for self-renewal, and are often more limited in both senses." [https://doi.org/10.1016/B978-0-12-409503-8.00002-0, ISBN:978-1-62808-994-3] +subset: cellxgene_subset is_a: CL:0011115 ! precursor cell intersection_of: CL:0011115 ! precursor cell intersection_of: develops_from CL:0000034 ! stem cell @@ -2043,6 +2112,7 @@ id: CL:0011115 name: precursor cell def: "A cell that, by division or terminal differentiation, can give rise to other cell types." [GOC:dos] comment: Work is needed on GO 'cell differentiation' before it is clear whether the equivalent class definition 'native cell' that capable_of some 'cell differentiation' works. Also, may want to consider merging this with non-terminally differentiated cell. +subset: cellxgene_subset is_a: CL:0000000 ! cell intersection_of: CL:0000000 ! cell intersection_of: capable_of GO:0030154 ! cell differentiation @@ -2070,17 +2140,6 @@ relationship: bearer_of PATO:0002094 ! basophilic relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2009-12-22T04:24:54Z -[Term] -id: CL:0017505 -name: increased nucleus size -def: "A nucleus size quality which is relatively high compared to the amount of cytoplasm present in the same cell." [GOC:tfm] -is_a: GO:0005634 ! nucleus -intersection_of: GO:0005634 ! nucleus -intersection_of: bearer_of PATO:0000586 ! increased size -relationship: bearer_of PATO:0000586 ! increased size -relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 -creation_date: 2009-12-23T10:53:24Z - [Term] id: CL:1001610 name: bone marrow hematopoietic cell @@ -2596,7 +2655,7 @@ id: GO:0005575 name: cellular_component namespace: cellular_component alt_id: GO:0008372 -def: "A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex)." [GOC:pdt] +def: "A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex)." [GOC:pdt] comment: Note that, in addition to forming the root of the cellular component ontology, this term is recommended for the annotation of gene products whose cellular component is unknown. When this term is used for annotation, it indicates that no information was available about the cellular component of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this. subset: goslim_candida subset: goslim_chembl @@ -2627,8 +2686,8 @@ subset: goslim_metagenomics subset: goslim_mouse subset: goslim_pir subset: goslim_plant +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset synonym: "extracellular" EXACT [] xref: Wikipedia:Extracellular is_a: GO:0110165 ! cellular anatomical entity @@ -2724,8 +2783,8 @@ subset: goslim_flybase_ribbon subset: goslim_generic subset: goslim_metagenomics subset: goslim_pir +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset synonym: "chromatid" RELATED [] synonym: "interphase chromosome" NARROW [] synonym: "prophase chromosome" NARROW [] @@ -2759,8 +2818,8 @@ subset: goslim_chembl subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset xref: Wikipedia:Cytoplasm is_a: GO:0110165 ! cellular anatomical entity relationship: part_of GO:0005622 ! intracellular anatomical structure @@ -2822,8 +2881,8 @@ subset: goslim_generic subset: goslim_metagenomics subset: goslim_mouse subset: goslim_plant +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset synonym: "bacterial inner membrane" NARROW [] synonym: "cell membrane" EXACT [] synonym: "cellular membrane" EXACT [NIF_Subcellular:sao6433132645] @@ -2876,8 +2935,8 @@ def: "Any process in which a new genotype is formed by reassortment of genes res subset: goslim_drosophila subset: goslim_generic subset: goslim_pombe +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset is_a: GO:0006259 ! DNA metabolic process [Term] @@ -2895,7 +2954,7 @@ subset: goslim_chembl subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "single-organism transport" RELATED [] is_a: GO:0051234 ! establishment of localization property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20292" xsd:anyURI @@ -3744,8 +3803,8 @@ subset: goslim_flybase_ribbon subset: goslim_generic subset: goslim_mouse subset: goslim_pombe +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset synonym: "biological signaling" EXACT [] synonym: "signaling process" EXACT [] synonym: "signalling" EXACT [] @@ -3792,7 +3851,7 @@ id: GO:0030030 name: cell projection organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon." [GOC:jl, GOC:mah, http://www.cogsci.princeton.edu/~wn/] -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "cell projection organisation" EXACT [] synonym: "cell projection organization and biogenesis" RELATED [GOC:mah] synonym: "cell surface structure organization and biogenesis" RELATED [GOC:mah] @@ -3989,7 +4048,7 @@ subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_pir -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "matrisome" NARROW [] synonym: "proteinaceous extracellular matrix" EXACT [] xref: NIF_Subcellular:nlx_subcell_20090513 @@ -4358,7 +4417,7 @@ subset: goslim_agr subset: goslim_flybase_ribbon subset: goslim_mouse subset: goslim_pir -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "cell process" BROAD [] synonym: "cellular process" BROAD [] synonym: "cellular projection" EXACT [] @@ -4395,12 +4454,14 @@ alt_id: GO:0034960 alt_id: GO:0043283 alt_id: GO:0044259 def: "The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:mah] +subset: gocheck_do_not_annotate subset: goslim_pir synonym: "biopolymer metabolic process" EXACT [GOC:mtg_chebi_dec09] synonym: "macromolecule metabolism" EXACT [] synonym: "multicellular organismal macromolecule metabolic process" NARROW [] synonym: "organismal macromolecule metabolism" EXACT [] is_a: GO:0008152 ! metabolic process +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI [Term] id: GO:0043207 @@ -4418,7 +4479,7 @@ def: "Organized structure of distinctive morphology and function. Includes the n subset: goslim_chembl subset: goslim_generic subset: goslim_pir -subset: prokaryote_subset +subset: goslim_prokaryote xref: NIF_Subcellular:sao1539965131 xref: Wikipedia:Organelle is_a: GO:0110165 ! cellular anatomical entity @@ -4555,7 +4616,7 @@ synonym: "innate immunity" EXACT [GOC:pg] synonym: "nonspecific immune response" EXACT [] xref: Wikipedia:Innate_immune_system is_a: GO:0006955 ! immune response -is_a: GO:0098542 ! defense response to other organism +is_a: GO:0140546 ! defense response to symbiont [Term] id: GO:0045202 @@ -4814,6 +4875,7 @@ id: GO:0048856 name: anatomical structure development namespace: biological_process def: "The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome." [GO_REF:0000021] +subset: gocheck_do_not_annotate subset: goslim_chembl subset: goslim_generic subset: goslim_plant @@ -4822,6 +4884,7 @@ is_a: GO:0032502 ! developmental process intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of UBERON:0000061 ! anatomical structure relationship: results_in_development_of UBERON:0000061 ! anatomical structure +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI [Term] id: GO:0048869 @@ -4839,7 +4902,7 @@ def: "Any process involved in the controlled self-propelled movement of a cell t subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "cell locomotion" EXACT [] synonym: "cell movement" RELATED [] synonym: "movement of a cell" EXACT [] @@ -4960,7 +5023,7 @@ subset: goslim_agr subset: goslim_flybase_ribbon subset: goslim_mouse subset: goslim_pir -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "physiological response to stimulus" EXACT [] is_a: GO:0008150 ! biological_process @@ -5176,7 +5239,7 @@ subset: goslim_drosophila subset: goslim_generic subset: goslim_pir subset: goslim_pombe -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "cellular membrane organisation" EXACT [] synonym: "cellular membrane organization" EXACT [] synonym: "membrane organisation" EXACT [GOC:mah] @@ -5263,10 +5326,12 @@ id: GO:0071704 name: organic substance metabolic process namespace: biological_process def: "The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon." [GOC:mah] +subset: gocheck_do_not_annotate synonym: "organic molecular entity metabolic process" EXACT [] synonym: "organic molecular entity metabolism" EXACT [] synonym: "organic substance metabolism" EXACT [] is_a: GO:0008152 ! metabolic process +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI created_by: mah creation_date: 2010-03-08T03:32:18Z @@ -5289,7 +5354,7 @@ creation_date: 2010-09-10T01:39:16Z id: GO:0071944 name: cell periphery namespace: cellular_component -def: "The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures." [GOC:pdt] +def: "The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures." [GOC:pdt] subset: goslim_flybase_ribbon is_a: GO:0110165 ! cellular anatomical entity created_by: mah @@ -5366,7 +5431,7 @@ namespace: biological_process alt_id: GO:0009814 def: "Reactions triggered in response to the presence of another organism that act to protect the cell or organism from damage caused by that organism." [GOC:dos] subset: goslim_generic -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "defence response incompatible interaction" NARROW [] synonym: "defence response to pathogen, incompatible interaction" NARROW [] synonym: "defense response, incompatible interaction" NARROW [] @@ -5589,6 +5654,7 @@ subset: goslim_pir is_a: GO:0005575 ! cellular_component is_a: UBERON:0000061 ! anatomical structure property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24200" xsd:anyURI +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI created_by: kmv creation_date: 2019-08-12T18:01:37Z @@ -5647,6 +5713,16 @@ relationship: has_target_start_location GO:0005622 ! intracellular anatomical st created_by: pg creation_date: 2019-05-22T11:20:45Z +[Term] +id: GO:0140546 +name: defense response to symbiont +namespace: biological_process +def: "Reactions triggered in response to the presence of a symbiont that act to protect or prevent damage to the host." [GOC:pg] +is_a: GO:0098542 ! defense response to other organism +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20261" xsd:anyURI +created_by: pg +creation_date: 2020-11-11T17:19:06Z + [Term] id: GO:1901576 name: organic substance biosynthetic process @@ -6070,30 +6146,6 @@ subset: attribute_slim synonym: "relational shape quality" EXACT [] is_a: PATO:0000051 ! morphology -[Term] -id: PATO:0000068 -name: qualitative -namespace: quality -comment: TODO: define this or obsolete it and move children somewhere else. -is_a: PATO:0000001 ! quality - -[Term] -id: PATO:0000069 -name: deviation (from_normal) -namespace: quality -def: "A quality inhering in a bearer by virtue of the whether the bearer differs from normal or average." [PATOC:GVG] -subset: attribute_slim -is_a: PATO:0000068 ! qualitative - -[Term] -id: PATO:0000117 -name: size -namespace: quality -def: "A morphology quality inhering in a bearer by virtue of the bearer's physical magnitude." [WordNet:WordNet] -subset: attribute_slim -subset: scalar_slim -is_a: PATO:0000051 ! morphology - [Term] id: PATO:0000141 name: structure @@ -6117,36 +6169,6 @@ synonym: "round" RELATED [] synonym: "rounded" RELATED [] is_a: PATO:0000947 ! elliptic -[Term] -id: PATO:0000461 -name: normal -namespace: quality -def: "A quality inhering in a bearer by virtue of the bearer's exhibiting no deviation from normal or average." [PATOC:GVG] -subset: abnormal_slim -subset: mpath_slim -subset: value_slim -synonym: "average" RELATED [] -is_a: PATO:0000068 ! qualitative -property_value: RO:0002604 PATO:0000460 - -[Term] -id: PATO:0000586 -name: increased size -namespace: quality -alt_id: PATO:0001202 -def: "A size quality which is relatively high." [PATOC:GVG] -subset: value_slim -synonym: "big" RELATED [] -synonym: "enlarged" RELATED [] -synonym: "expanded" RELATED [] -synonym: "great" RELATED [] -synonym: "large" RELATED [] -is_a: PATO:0000117 ! size -is_a: PATO:0002305 ! increased object quality -intersection_of: PATO:0000117 ! size -intersection_of: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal -property_value: RO:0002604 PATO:0000587 - [Term] id: PATO:0000947 name: elliptic @@ -6430,32 +6452,6 @@ is_a: PATO:0002078 ! hollow relationship: dc-contributor https://orcid.org/0000-0002-2061-091X creation_date: 2011-06-08T06:33:50Z -[Term] -id: PATO:0002300 -name: increased quality -namespace: quality -def: "A quality that has a value that is increased compared to normal or average." [PATOC:GVG] -is_a: PATO:0000069 ! deviation (from_normal) -intersection_of: PATO:0000001 ! quality -intersection_of: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal -relationship: dc-contributor https://orcid.org/0000-0002-2061-091X -relationship: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal -property_value: RO:0002604 PATO:0002301 -creation_date: 2011-06-16T06:39:43Z - -[Term] -id: PATO:0002305 -name: increased object quality -namespace: quality -def: "A quality of an object that has a value that is increased compared to normal or average." [PATOC:GVG] -is_a: PATO:0001241 ! physical object quality -is_a: PATO:0002300 ! increased quality -intersection_of: PATO:0001241 ! physical object quality -intersection_of: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal -relationship: dc-contributor https://orcid.org/0000-0002-2061-091X -property_value: RO:0002604 PATO:0002303 -creation_date: 2011-06-16T06:54:01Z - [Term] id: PATO:0002309 name: fiber shaped @@ -6518,6 +6514,16 @@ comment: A complete coverage of this domain would subclasses homopolymeric, copo subset: value_slim is_a: PATO:0000141 ! structure +[Term] +id: PATO:0040072 +name: high nuclear/cytoplasmic ratio +namespace: quality +def: "A quality inhering in a cell by virtue of the cell having a high nuclear/cytoplasmic ratio." [http://lymerick.net/blood-cells.pdf, Wikipedia:NC_ratio&oldid=931936284] +comment: A high nuclear/cytolasmic ratio is 70% or higher. +synonym: "high N:C ratio" EXACT [] +is_a: PATO:0001396 ! cellular quality +created_by: http://orcid.org/0000-0001-5208-3432 + [Term] id: PATO:0070044 name: anatomical structure quality @@ -7405,7 +7411,7 @@ xref: CALOHA:TS-2043 xref: EHDAA2:0001824 xref: EHDAA:500 xref: EMAPA:35955 -xref: FBbt:00005155 +xref: FBbt:00005155 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: GAID:63 xref: HAO:0000930 xref: MA:0000017 @@ -7446,7 +7452,7 @@ def: "Dense regular connective tissue that connects muscle to bone[VSAO]." [GO_R subset: pheno_slim subset: uberon_slim synonym: "sinew" RELATED [Wikipedia:Tendon] -synonym: "tendo" RELATED LATIN [Wikipedia:Tendon] +synonym: "tendo" RELATED OMO:0003011 [Wikipedia:Tendon] xref: AEO:0000091 xref: BTO:0001356 xref: CALOHA:TS-1021 @@ -7488,7 +7494,7 @@ synonym: "ducts" RELATED OMO:0003004 [XAO:0004000] synonym: "exocrine duct" NARROW [] synonym: "exocrine gland duct" NARROW [] xref: AAO:0011123 -xref: FBbt:00100314 +xref: FBbt:00100314 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:30320 xref: galen:Duct xref: NCIT:C12948 @@ -7539,7 +7545,7 @@ xref: BILA:0000003 xref: CARO:0000003 xref: EHDAA2:0003003 xref: EMAPA:0 -xref: FBbt:00007001 +xref: FBbt:00007001 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:305751 xref: FMA:67135 xref: GAID:781 @@ -7809,13 +7815,13 @@ synonym: "fertilized egg stage" RELATED [] synonym: "one cell stage" EXACT [] synonym: "one-cell stage" RELATED [VHOG:0000745] synonym: "zygote" RELATED [VHOG:0000745] -synonym: "zygotum" RELATED LATIN [Wikipedia:Zygote] +synonym: "zygotum" RELATED OMO:0003011 [Wikipedia:Zygote] xref: BilaDO:0000005 xref: BILS:0000106 xref: EFO:0001322 xref: EHDAA:27 xref: FBdv:00005288 -xref: IDOMAL:0000302 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: IDOMAL:0000302 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: NCIT:C12601 xref: PdumDv:0000100 xref: VHOG:0000745 @@ -7963,13 +7969,13 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "adult mouth" NARROW [] -synonym: "cavital oralis" RELATED LATIN [Wikipedia:Mouth] +synonym: "cavital oralis" RELATED OMO:0003011 [Wikipedia:Mouth] synonym: "cavitas oris" RELATED [BTO:0001090] synonym: "cavum oris" RELATED [BTO:0001090] synonym: "mouth cavity" RELATED [BTO:0001090] synonym: "oral region" RELATED [EHDAA2:0001326] synonym: "oral vestibule" RELATED [BTO:0001090] -synonym: "regio oralis" EXACT LATIN [BTO:0004698, FMA:49184, FMA:TA] +synonym: "regio oralis" EXACT OMO:0003011 [BTO:0004698, FMA:49184, FMA:TA] synonym: "rima oris" RELATED [BTO:0001090] synonym: "stoma" RELATED [] synonym: "stomatodaeum" RELATED [VHOG:0000812] @@ -7984,7 +7990,7 @@ xref: EFO:0000825 xref: EHDAA2:0001326 xref: EHDAA:542 xref: EMAPA:16262 -xref: FBbt:00003126 +xref: FBbt:00003126 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:49184 xref: GAID:75 xref: galen:Mouth @@ -8102,7 +8108,7 @@ xref: CALOHA:TS-2101 xref: CARO:0000004 xref: EHDAA2:0003004 xref: EMAPA:35178 -xref: FBbt:00007019 +xref: FBbt:00007019 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:9669 xref: galen:BodySubstance xref: HAO:0000004 @@ -8137,7 +8143,7 @@ xref: AEO:0000005 xref: BILA:0000005 xref: CARO:0000005 xref: EHDAA2:0003005 -xref: FBbt:00007017 +xref: FBbt:00007017 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:5897 xref: HAO:0000005 xref: NCIT:C94478 @@ -8165,7 +8171,7 @@ xref: AEO:0000006 xref: BILA:0000006 xref: CARO:0000006 xref: EHDAA2:0003006 -xref: FBbt:00007016 +xref: FBbt:00007016 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:67165 xref: HAO:0000006 xref: TAO:0001836 @@ -8191,7 +8197,7 @@ xref: AEO:0000007 xref: BILA:0000007 xref: CARO:0000007 xref: EHDAA2:0003007 -xref: FBbt:00007015 +xref: FBbt:00007015 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:67112 xref: HAO:0000007 xref: TAO:0001835 @@ -8229,11 +8235,11 @@ xref: EHDAA2:0003011 xref: EHDAA:392 xref: EMAPA:16103 xref: EV:0100000 -xref: FBbt:00004856 +xref: FBbt:00004856 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:7149 xref: galen:AnatomicalSystem xref: HAO:0000011 -xref: IDOMAL:0002460 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: IDOMAL:0002460 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: MA:0000003 xref: NCIT:C12919 xref: SCTID:278195005 @@ -8284,7 +8290,7 @@ xref: EHDAA2:0003191 xref: EHDAA:1 xref: EMAPA:25765 xref: EV:0100016 -xref: FBbt:00000001 +xref: FBbt:00000001 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:256135 xref: galen:Organism xref: HAO:0000012 @@ -8329,7 +8335,7 @@ xref: CARO:0000032 xref: EFO:0000808 xref: EHDAA2:0003032 xref: EMAPA:36031 -xref: FBbt:00007009 +xref: FBbt:00007009 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:7153 xref: galen:BodyPart xref: HAO:0000032 @@ -8365,7 +8371,7 @@ xref: AEO:0000040 xref: BILA:0000040 xref: CARO:0000040 xref: EHDAA2:0003040 -xref: FBbt:00007013 +xref: FBbt:00007013 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:63863 xref: HAO:0000040 xref: TAO:0000382 @@ -8385,8 +8391,7 @@ namespace: uberon def: "Anatomical group whose component anatomical structures lie in close proximity to each other." [FBbt:00007277] subset: common_anatomy subset: upper_level -xref: FBbt:00007277 -xref: IDOMAL:0002461 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: FBbt:00007277 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: VHOG:0001737 is_a: UBERON:0034923 ! disconnected anatomical group relationship: present_in_taxon NCBITaxon:33090 @@ -8412,7 +8417,7 @@ xref: CALOHA:TS-2119 xref: CARO:0000042 xref: EHDAA2:0003042 xref: EHDAA:46 -xref: FBbt:00005835 +xref: FBbt:00005835 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:85537 xref: HAO:0000042 xref: NCIT:C34055 @@ -8448,7 +8453,7 @@ xref: CALOHA:TS-2090 xref: CARO:0000043 xref: EHDAA2:0003043 xref: EMAPA:35868 -xref: FBbt:00007003 +xref: FBbt:00007003 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:9637 xref: galen:Tissue xref: HAO:0000043 @@ -8483,7 +8488,7 @@ xref: AEO:0000055 xref: BILA:0000055 xref: CARO:0000055 xref: EHDAA2:0003055 -xref: FBbt:00007010 +xref: FBbt:00007010 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: HAO:0000055 xref: TAO:0001488 xref: TGMA:0001847 @@ -8516,7 +8521,7 @@ xref: CALOHA:TS-0288 xref: CARO:0000066 xref: EHDAA2:0003066 xref: EMAPA:32738 -xref: FBbt:00007005 +xref: FBbt:00007005 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:9639 xref: GAID:402 xref: HAO:0000066 @@ -8620,11 +8625,11 @@ xref: EHDAA2:0000002 xref: EHDAA2_RETIRED:0003236 xref: EHDAA:38 xref: EMAPA:16039 -xref: FBbt:00000052 +xref: FBbt:00000052 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:69068 xref: GAID:963 xref: http://neurolex.org/wiki/Category\:Embryonic_organism -xref: IDOMAL:0000646 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: IDOMAL:0000646 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: MAT:0000226 xref: MESH:D004622 xref: MIAA:0000019 @@ -8664,7 +8669,7 @@ xref: AAO:0000480 xref: BILA:0000035 xref: BTO:0000556 xref: EMAPA:36033 -xref: FBbt:00000110 +xref: FBbt:00000110 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:69069 xref: GAID:1303 xref: MESH:D005855 @@ -8699,7 +8704,7 @@ xref: EFO:0000414 xref: EHDAA2:0000428 xref: EMAPA:16069 xref: EV:0100003 -xref: FBbt:00000111 +xref: FBbt:00000111 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:69070 xref: GAID:1304 xref: MAT:0000155 @@ -8740,7 +8745,7 @@ xref: EFO:0002545 xref: EHDAA2:0000436 xref: EMAPA:16062 xref: EV:0100005 -xref: FBbt:00000125 +xref: FBbt:00000125 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:69071 xref: GAID:1305 xref: MAT:0000175 @@ -8786,7 +8791,7 @@ xref: EHDAA:160 xref: EHDAA:183 xref: EMAPA:16083 xref: EV:0100006 -xref: FBbt:00000126 +xref: FBbt:00000126 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:69072 xref: GAID:522 xref: MAT:0000174 @@ -8830,7 +8835,7 @@ synonym: "stomodeal-hypophyseal primordium" BROAD [XAO:0000269] xref: BTO:0004224 xref: EHDAA2:0001929 xref: EMAPA:16263 -xref: FBbt:00000439 +xref: FBbt:00000439 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:295846 xref: NCIT:C34306 xref: TAO:0001290 @@ -8868,7 +8873,7 @@ xref: EFO:0002969 xref: EHDAA2:0002224 xref: EMAPA:35306 xref: EV:0100128 -xref: FBbt:00005068 +xref: FBbt:00005068 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:9668 xref: GAID:439 xref: MA:0000012 @@ -8916,7 +8921,7 @@ xref: BTO:0000439 xref: CALOHA:TS-0309 xref: EFO:0000827 xref: EV:0100336 -xref: FBbt:00005162 +xref: FBbt:00005162 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: GAID:69 xref: MAT:0000140 xref: MESH:D005123 @@ -8996,7 +9001,7 @@ xref: BTO:0000058 xref: CALOHA:TS-1293 xref: EFO:0000793 xref: EV:0100056 -xref: FBbt:00005055 +xref: FBbt:00005055 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:7152 xref: GAID:278 xref: galen:DigestiveSystem @@ -9037,9 +9042,10 @@ namespace: uberon def: "Organ system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis[WP]." [Wikipedia:Circulatory_system] subset: human_reference_atlas subset: uberon_slim -synonym: "systema cardiovasculare" RELATED LATIN [Wikipedia:Circulatory_system] +synonym: "systema cardiovasculare" RELATED OMO:0003011 [Wikipedia:Circulatory_system] xref: AAO:0000959 xref: CALOHA:TS-2103 +xref: MESH:D002319 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} xref: VHOG:0001248 xref: Wikipedia:Circulatory_system is_a: UBERON:0000467 ! anatomical system @@ -9078,7 +9084,7 @@ synonym: "muscles" RELATED [] synonym: "muscles set" EXACT [] synonym: "musculature" EXACT [] synonym: "musculature system" RELATED [] -synonym: "musculi" EXACT LATIN [FMA:32558, FMA:TA] +synonym: "musculi" EXACT OMO:0003011 [FMA:32558, FMA:TA] synonym: "set of muscles" EXACT [FMA:32558] synonym: "set of skeletal muscles" EXACT [MA:0000165] xref: AAO:0011066 @@ -9109,12 +9115,13 @@ namespace: uberon def: "The nervous system is an organ system containing predominantly neuron and glial cells. In bilaterally symmetrical organism, it is arranged in a network of tree-like structures connected to a central body. The main functions of the nervous system are to regulate and control body functions, and to receive sensory input, process this information, and generate behavior [CUMBO]." [BIRNLEX:844, ISBN:0-14-051288-8, ISBN:3110148986, NLM:nervous+system, WB:rynl, Wikipedia:Nervous_system, ZFIN:curator] subset: cumbo subset: efo_slim +subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "nerve net" NARROW [Wikipedia:Nerve_net] synonym: "neurological system" EXACT [GO:0050877] -synonym: "systema nervosum" RELATED LATIN [Wikipedia:Nervous_system] +synonym: "systema nervosum" RELATED OMO:0003011 [Wikipedia:Nervous_system] xref: AAO:0000324 xref: BILA:0000079 xref: BIRNLEX:844 @@ -9125,7 +9132,7 @@ xref: EHDAA2:0001246 xref: EHDAA:826 xref: EMAPA:16469 xref: EV:0100162 -xref: FBbt:00005093 +xref: FBbt:00005093 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:7157 xref: GAID:466 xref: MA:0000016 @@ -9156,6 +9163,7 @@ relationship: has_part CL:0000540 ! neuron relationship: immediate_transformation_of UBERON:0016880 {source="Bgee:AN"} ! future nervous system relationship: never_in_taxon NCBITaxon:6040 relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa +relationship: present_in_taxon NCBITaxon:9606 property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/b/b2/TE-Nervous_system_diagram.svg" xsd:anyURI property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/b/ba/Nervous_system_diagram.png" xsd:anyURI property_value: UBPROP:0000001 "A regulatory system of the body that consists of neurons and neuroglial cells. The nervous system is divided into two parts, the central nervous system (CNS) and the peripheral nervous system (PNS). (Source: BioGlossary, www.Biology-Text.com)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000396", ontology="TAO", source="ZFIN:curator"} @@ -9171,13 +9179,14 @@ namespace: uberon def: "The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the neural tube derivatives: the brain and spinal cord. In invertebrates it includes central ganglia plus nerve cord." [GO:0021551, http://www.frontiersinzoology.com/content/7/1/29, https://sourceforge.net/p/geneontology/ontology-requests/11422/] subset: cumbo subset: efo_slim +subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "cerebrospinal axis" NARROW [FMA:55675] synonym: "CNS" EXACT OMO:0003000 [] synonym: "neuraxis" RELATED [FMA:55675] -synonym: "systema nervosum centrale" EXACT LATIN [FMA:55675, FMA:TA] +synonym: "systema nervosum centrale" EXACT OMO:0003011 [FMA:55675, FMA:TA] xref: AAO:0000090 xref: BAMS:CNS xref: BILA:0000080 @@ -9190,7 +9199,7 @@ xref: EHDAA:828 xref: EMAPA:16470 xref: EMAPA:16754 xref: EV:0100163 -xref: FBbt:00005094 +xref: FBbt:00005094 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:55675 xref: GAID:570 xref: MA:0000167 @@ -9211,6 +9220,7 @@ relationship: immediate_transformation_of UBERON:0016879 {source="Bgee:AN"} ! fu relationship: never_in_taxon NCBITaxon:147099 {source="Wikipedia:Acoelomorpha"} relationship: only_in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of UBERON:0001016 ! nervous system +relationship: present_in_taxon NCBITaxon:9606 property_value: UBPROP:0000001 "Part of the nervous system which includes the brain and spinal cord.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000090", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000001 "The brain and spinal cord. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000012", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "The central nervous system (CNS) is the part of the nervous system which includes the brain, spinal cord, and nerve cell layer of the retina (CUMBO)." xsd:string {source="BIRNLEX:1099"} @@ -9224,8 +9234,8 @@ def: "Anatomical system that overlaps the nervous system and is responsible for subset: efo_slim subset: uberon_slim subset: vertebrate_core -synonym: "organa sensuum" EXACT LATIN [FMA:75259, FMA:TA] -synonym: "organa sensuum" RELATED LATIN [Wikipedia:Sensory_system] +synonym: "organa sensuum" EXACT OMO:0003011 [FMA:75259, FMA:TA] +synonym: "organa sensuum" RELATED OMO:0003011 [Wikipedia:Sensory_system] synonym: "sense organ subsystem" EXACT [] synonym: "sense organs" EXACT [FMA:75259] synonym: "sense organs set" EXACT [FMA:75259] @@ -9239,7 +9249,7 @@ xref: BILA:0000099 xref: EFO:0000805 xref: EHDAA2:0003094 xref: EMAPA:16192 -xref: FBbt:00007692 +xref: FBbt:00007692 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:75259 xref: MA:0002442 xref: MAT:0000031 @@ -9268,7 +9278,7 @@ subset: uberon_slim subset: vertebrate_core synonym: "neural primordium" RELATED [] synonym: "presumptive central nervous system" RELATED [] -synonym: "tubus neuralis" RELATED LATIN [Wikipedia:Neural_tube] +synonym: "tubus neuralis" RELATED OMO:0003011 [Wikipedia:Neural_tube] xref: AAO:0010617 xref: BTO:0001057 xref: CALOHA:TS-2371 @@ -9280,7 +9290,7 @@ xref: EMAPA:16164 xref: EMAPA:16757 xref: FMA:293882 xref: MAT:0000069 -xref: MESH:D054259 +xref: MESH:D054259 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: MIAA:0000069 xref: NCIT:C34226 xref: neuronames:1365 @@ -9316,7 +9326,7 @@ xref: BILA:0000000 xref: BIRNLEX:6 xref: CARO:0000000 xref: EHDAA2:0002229 -xref: FBbt:10000000 +xref: FBbt:10000000 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:62955 xref: HAO:0000000 xref: MA:0000001 @@ -9542,10 +9552,11 @@ xref: BTO:0000545 xref: EHDAA2:0000726 xref: EHDAA:518 xref: EMAPA:16247 -xref: FBbt:00003125 +xref: FBbt:00003125 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:45615 xref: galen:AlimentaryTract xref: MA:0000917 +xref: MESH:D041981 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} xref: NCIT:C34082 xref: TAO:0000112 xref: TGMA:0001819 @@ -9644,7 +9655,7 @@ xref: BILA:0000034 xref: BTO:0000174 xref: CALOHA:TS-2110 xref: EFO:0000461 -xref: FBbt:00004208 +xref: FBbt:00004208 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:69067 xref: GAID:407 xref: MESH:D004628 @@ -9794,7 +9805,7 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "embryonic notocord" EXACT [] -synonym: "notochorda" RELATED LATIN [Wikipedia:Notochord] +synonym: "notochorda" RELATED OMO:0003011 [Wikipedia:Notochord] synonym: "notocord" EXACT [ZFA:0000135] xref: AAO:0000327 xref: BTO:0001768 @@ -9853,7 +9864,7 @@ synonym: "epithelial somite" RELATED [https://github.com/obophenotype/uberon/wik synonym: "mesodermal cluster" BROAD [GO:0001756] synonym: "somites" RELATED OMO:0003004 [] synonym: "somitic mesoderm" RELATED [] -synonym: "somitus" RELATED LATIN [Wikipedia:Somite] +synonym: "somitus" RELATED OMO:0003011 [Wikipedia:Somite] xref: AAO:0010569 xref: AEO:0001015 xref: BTO:0001558 @@ -9923,7 +9934,7 @@ comment: Gene notes: Many factors and genes, such as Pax3 (Tremblay et al., 1995 subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "crista neuralis" RELATED LATIN [Wikipedia:Neural_crest] +synonym: "crista neuralis" RELATED OMO:0003011 [Wikipedia:Neural_crest] synonym: "NC" EXACT OMO:0003000 [XAO:0000048] synonym: "neural crest material" RELATED [VHOG:0000057] xref: AAO:0010578 @@ -9969,7 +9980,7 @@ namespace: uberon def: "Embryonic ectoderm that gives rise to nervous tissue." [Wikipedia:Neuroectoderm] subset: uberon_slim subset: vertebrate_core -synonym: "epithelium tubi neuralis; neuroectoderma" RELATED LATIN [Wikipedia:Neuroectoderm] +synonym: "epithelium tubi neuralis; neuroectoderma" RELATED OMO:0003011 [Wikipedia:Neuroectoderm] synonym: "neuaral ectoderm" RELATED [] synonym: "neural ectoderm" EXACT [] synonym: "neuroectoderm" EXACT [] @@ -9983,7 +9994,7 @@ xref: EHDAA:1498 xref: EHDAA:255 xref: EMAPA:16073 xref: EV:0100004 -xref: FBbt:00001057 +xref: FBbt:00001057 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:87657 xref: MAT:0000176 xref: MIAA:0000176 @@ -10010,7 +10021,7 @@ subset: organ_slim subset: pheno_slim subset: uberon_slim synonym: "ducted gland" EXACT [AEO:0000097] -synonym: "glandula exocrina" EXACT LATIN [Wikipedia:Exocrine_gland] +synonym: "glandula exocrina" EXACT OMO:0003011 [Wikipedia:Exocrine_gland] xref: AEO:0000097 xref: BTO:0000765 xref: CALOHA:TS-2012 @@ -10043,7 +10054,7 @@ subset: uberon_slim synonym: "ductless gland" EXACT [AEO:0000098] synonym: "ductless gland" RELATED [Wikipedia:Ductless_gland] synonym: "glandula endocrina" EXACT [] -synonym: "glandulae endocrinae" RELATED LATIN [Wikipedia:Endocrine_gland] +synonym: "glandulae endocrinae" RELATED OMO:0003011 [Wikipedia:Endocrine_gland] xref: AEO:0000098 xref: BTO:0001488 xref: CALOHA:TS-1300 @@ -10074,8 +10085,8 @@ subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "medulla of bone" RELATED [BTO:0000141] -synonym: "medulla ossea" EXACT LATIN [BTO:0000141, FMA:9608] -synonym: "medulla ossium" EXACT LATIN [BTO:0000141, Wikipedia:Bone_marrow] +synonym: "medulla ossea" EXACT OMO:0003011 [BTO:0000141, FMA:9608] +synonym: "medulla ossium" EXACT OMO:0003011 [BTO:0000141, Wikipedia:Bone_marrow] synonym: "medullary bone" RELATED [] xref: AAO:0011007 xref: BTO:0000141 @@ -10310,7 +10321,7 @@ subset: efo_slim subset: pheno_slim subset: uberon_slim synonym: "Druese" RELATED [BTO:0000522] -synonym: "glandula" RELATED LATIN [BTO:0000522, Wikipedia:Gland] +synonym: "glandula" RELATED OMO:0003011 [BTO:0000522, Wikipedia:Gland] synonym: "glandular organ" EXACT [http://orcid.org/0000-0002-6601-2165] xref: AAO:0000212 xref: AEO:0000096 @@ -10321,7 +10332,7 @@ xref: EHDAA:2161 xref: EHDAA:4475 xref: EHDAA:6522 xref: EMAPA:18425 -xref: FBbt:00100317 +xref: FBbt:00100317 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:7146 xref: FMA:86294 xref: galen:Gland @@ -10354,7 +10365,7 @@ subset: vertebrate_core synonym: "blastocyst" RELATED [] synonym: "ectoblast" RELATED [MP:0003886] synonym: "epiblast" EXACT [VHOG:0000243] -synonym: "epiblastus" RELATED LATIN [Wikipedia:Epiblast] +synonym: "epiblastus" RELATED OMO:0003011 [Wikipedia:Epiblast] synonym: "primitive ectoderm" RELATED [VHOG:0000243] xref: BTO:0004593 xref: FMA:296704 @@ -10482,7 +10493,7 @@ def: "A region of embryonic ectodermal cells that lie directly above the notocho subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "lamina neuralis" RELATED LATIN [Wikipedia:Neural_plate] +synonym: "lamina neuralis" RELATED OMO:0003011 [Wikipedia:Neural_plate] synonym: "presumptive central nervous system" RELATED [] xref: AAO:0011072 xref: BTO:0001765 @@ -10492,7 +10503,7 @@ xref: EHDAA:346 xref: EHDAA:902 xref: EMAPA:35593 xref: FMA:293879 -xref: MESH:D054258 +xref: MESH:D054258 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: NCIT:C34225 xref: neuronames:1362 xref: RETIRED_EHDAA2:0001252 @@ -10520,7 +10531,7 @@ def: "The paraxial mesoderm is the mesoderm located bilaterally adjacent to the subset: efo_slim subset: uberon_slim subset: vertebrate_core -synonym: "mesoderma paraxiale" RELATED LATIN [Wikipedia:Paraxial_mesoderm] +synonym: "mesoderma paraxiale" RELATED OMO:0003011 [Wikipedia:Paraxial_mesoderm] synonym: "paraxial mesenchyme" EXACT [https://github.com/obophenotype/uberon/issues/30, https://github.com/obophenotype/uberon/wiki/The-neural-crest, ZFA:0000255] synonym: "somitic mesoderm" EXACT [ISBN:9780878932504] xref: AAO:0010568 @@ -10559,7 +10570,7 @@ synonym: "lateral mesoderm" EXACT [GO:0048368] synonym: "lateral plate" RELATED [] synonym: "lateral plate mesenchyme" RELATED [EHDAA2:0000919] synonym: "LPM" EXACT OMO:0003000 [ZFA:0000121] -synonym: "mesoderma laminae lateralis" RELATED LATIN [Wikipedia:Lateral_plate_mesoderm] +synonym: "mesoderma laminae lateralis" RELATED OMO:0003011 [Wikipedia:Lateral_plate_mesoderm] xref: AAO:0010574 xref: EHDAA2:0000919 xref: EHDAA:379 @@ -10599,7 +10610,7 @@ synonym: "myomere" RELATED [] synonym: "myomeres" EXACT OMO:0003004 [TAO:0001056] synonym: "myotome region" RELATED [] synonym: "myotomes" RELATED [] -synonym: "myotomus" RELATED LATIN [Wikipedia:Myotome] +synonym: "myotomus" RELATED OMO:0003011 [Wikipedia:Myotome] xref: AAO:0011067 xref: AEO:0001018 xref: BTO:0000742 @@ -10657,7 +10668,7 @@ def: "Portion of tissue composed of mesenchymal cells (motile cells that develop subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "mesenchyma" RELATED LATIN [Wikipedia:Mesenchyme] +synonym: "mesenchyma" RELATED OMO:0003011 [Wikipedia:Mesenchyme] synonym: "mesenchymal tissue" EXACT [] synonym: "mesenchyme tissue" EXACT [] synonym: "portion of mesenchymal tissue" EXACT [] @@ -10714,7 +10725,7 @@ def: "Epithelial tubes transport gases, liquids and cells from one site to anoth synonym: "epithelial or endothelial tube" EXACT [] xref: AEO:0000114 xref: EHDAA2:0003114 -xref: FBbt:00007474 +xref: FBbt:00007474 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0000025 ! tube is_a: UBERON:0000483 ! epithelium intersection_of: UBERON:0000483 ! epithelium @@ -10891,7 +10902,7 @@ synonym: "trilaminar disk" RELATED [https://orcid.org/0000-0002-6601-2165] synonym: "trilaminar germ" RELATED [https://orcid.org/0000-0002-6601-2165] xref: BILA:0000060 xref: BTO:0001403 -xref: FBbt:00005317 +xref: FBbt:00005317 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:293108 xref: GAID:1302 xref: MESH:D005775 @@ -10995,7 +11006,7 @@ namespace: uberon def: "Anatomical structure that connects two or more adjacent skeletal elements or hardened body parts." [http://orcid.org/0000-0002-6601-2165] subset: grouping_class synonym: "joint" NARROW [] -xref: FBbt:00005811 +xref: FBbt:00005811 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0034921 ! multi organ part structure relationship: part_of UBERON:0004770 ! articular system @@ -11011,7 +11022,7 @@ synonym: "gut section" RELATED [FBbt:00100315] synonym: "intestinal tract" RELATED [] synonym: "segment of intestinal tract" RELATED [] synonym: "subdivision of alimentary system" RELATED [FMA:71131] -xref: FBbt:00100315 +xref: FBbt:00100315 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:71131 is_a: UBERON:0013522 ! subdivision of tube intersection_of: UBERON:0013522 ! subdivision of tube @@ -11153,7 +11164,7 @@ name: photoreceptor array namespace: uberon def: "An array of photoreceptors and any supporting cells found in an eye." [https://orcid.org/0000-0002-6601-2165] synonym: "light-sensitive tissue" EXACT [] -xref: FBbt:00004200 +xref: FBbt:00004200 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0004923 ! organ component layer intersection_of: UBERON:0004923 ! organ component layer intersection_of: composed_primarily_of CL:0000210 ! photoreceptor cell @@ -11173,7 +11184,7 @@ synonym: "developmental tissue" RELATED [MIAA:0000019] xref: AEO:0000125 xref: CALOHA:TS-2122 xref: EHDAA2:0003125 -xref: FBbt:00007006 +xref: FBbt:00007006 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:292313 xref: MIAA:0000019 is_a: UBERON:0000465 ! material anatomical entity @@ -11204,7 +11215,7 @@ namespace: uberon def: "An acellular membrane that is part of the epithelium, lies adjacent to the epithelial cells, and is the fusion of the the basal lamina and the reticular lamina." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Basement_membrane] synonym: "basement membrane" RELATED [FMA:63872] synonym: "basement membrane of connective tissue" EXACT [FMA:63872] -synonym: "membrana basalis" EXACT LATIN [Wikipedia:Basement_membrane] +synonym: "membrana basalis" EXACT OMO:0003011 [Wikipedia:Basement_membrane] xref: AAO:0010596 xref: FMA:63872 xref: GAID:915 @@ -11569,7 +11580,7 @@ subset: common_anatomy subset: upper_level synonym: "multicellular structure" EXACT [FBbt:00100313] xref: CARO:0010000 -xref: FBbt:00100313 +xref: FBbt:00100313 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0000061 ! anatomical structure intersection_of: UBERON:0000061 ! anatomical structure intersection_of: has_quality PATO:0001993 ! multicellular @@ -11626,8 +11637,9 @@ name: organ system subdivision namespace: uberon def: "A subdivision of an anatomical system." [http://orcid.org/0000-0002-6601-2165] subset: common_anatomy +subset: human_reference_atlas subset: upper_level -xref: FBbt:00007330 +xref: FBbt:00007330 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:67509 xref: SCTID:91690000 is_a: UBERON:0010000 {source="FBbt"} ! multicellular anatomical structure @@ -11635,6 +11647,7 @@ relationship: part_of UBERON:0000467 ! anatomical system relationship: present_in_taxon NCBITaxon:33090 relationship: present_in_taxon NCBITaxon:33208 ! Metazoa relationship: present_in_taxon NCBITaxon:4751 +relationship: present_in_taxon NCBITaxon:9606 [Term] id: UBERON:0011676 @@ -11803,7 +11816,6 @@ id: UBERON:0013702 name: body proper namespace: uberon def: "The region of the organism associated with the visceral organs." [AEO:0000103] -subset: human_reference_atlas subset: non_informative synonym: "body" RELATED [AEO:0000103] synonym: "whole body" RELATED [BTO:0001489] @@ -11813,7 +11825,6 @@ xref: EMAPA:36031 xref: FMA:231424 is_a: UBERON:0000475 {source="AEO"} ! organism subdivision relationship: part_of UBERON:0013701 ! main body axis -relationship: present_in_taxon NCBITaxon:9606 property_value: UBPROP:0000001 "Cardinal body part, which consists of a maximal set of diverse subclasses of organ and organ part spatially associated with the vertebral column and ribcage. Examples: There is only one body proper[FMA:231424]." xsd:string {source="FMA:231424"} [Term] @@ -11821,6 +11832,7 @@ id: UBERON:0014892 name: skeletal muscle organ, vertebrate namespace: uberon def: "A muscle organ that consists of skeletal muscle tissue ensheathed in epimysium, that develops from myotome and that is innervated by some somatic motor neuron. Skeletal muscles are typically attached (via a tendon) to a bone but there are exceptions (e.g. intrinsic tongue muscles)." [GOC:dos] +subset: human_reference_atlas synonym: "skeletal muscle" BROAD [] xref: AAO:0011099 xref: BTO:0001103 @@ -11851,6 +11863,7 @@ relationship: composed_primarily_of UBERON:0001134 ! skeletal muscle tissue relationship: develops_from UBERON:0003082 ! myotome relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of UBERON:0018254 ! skeletal musculature +relationship: present_in_taxon NCBITaxon:9606 relationship: surrounded_by UBERON:0011899 ! epimysium relationship: synapsed_by CL:0000100 ! motor neuron @@ -11860,7 +11873,7 @@ name: non-connected functional system namespace: uberon def: "An anatomical group whose component structures share a common function." [AEO:0000093, AEO:JB, FBbt:00007278, FBC:DOS] xref: AEO:0000093 -xref: FBbt:00007278 +xref: FBbt:00007278 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0034923 ! disconnected anatomical group [Term] @@ -11980,12 +11993,14 @@ id: UBERON:0018254 name: skeletal musculature namespace: uberon subset: grouping_class +subset: human_reference_atlas xref: EHDAA2:0001842 xref: EMAPA:35578 xref: MA:0000165 is_a: UBERON:0000061 ! anatomical structure relationship: composed_primarily_of UBERON:0014892 ! skeletal muscle organ, vertebrate relationship: part_of UBERON:0000383 {source="MA"} ! musculature of body +relationship: present_in_taxon NCBITaxon:9606 property_value: editor_note "Added for consistency with MA EMAPA and EHDAA2. See https://github.com/obophenotype/mouse-anatomy-ontology/issues/104" xsd:string [Term] @@ -12017,7 +12032,7 @@ namespace: uberon def: "Material anatomical entity consisting of multiple anatomical structures that are not connected to each other." [CARO:0020000] subset: common_anatomy xref: CARO:0020000 -xref: FBbt:00007276 +xref: FBbt:00007276 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0000465 {source="CARO"} ! material anatomical entity relationship: composed_primarily_of UBERON:0000061 ! anatomical structure relationship: has_component UBERON:0000061 {minCardinality="2"} ! anatomical structure @@ -12467,20 +12482,6 @@ property_value: seeAlso "https://github.com/obophenotype/uberon/wiki/Part-disjoi is_a: RO:0002323 ! mereotopologically related to expand_expression_to: "BFO_0000051 exactly 0 (BFO_0000050 some ?Y)" [] -[Typedef] -id: RO:0002203 -name: develops into -def: "inverse of develops from" [] -subset: RO:0002259 -property_value: IAO:0000114 IAO:0000125 -property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 -property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172 -property_value: IAO:0000117 https://orcid.org/0000-0003-1980-3228 -is_transitive: true -is_a: has_potential_to_develop_into ! has potential to develop into -is_a: RO:0002286 ! developmentally succeeded by -is_a: RO:0002388 ! has potential to directly develop into - [Typedef] id: RO:0002206 name: expressed in @@ -12501,7 +12502,7 @@ def: "inverse of directly develops from" [] subset: RO:0002259 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000118 "developmental precursor of" xsd:string -is_a: RO:0002203 ! develops into +is_a: develops_into ! develops into [Typedef] id: RO:0002222 @@ -12531,7 +12532,7 @@ def: "inverse of has developmental contribution from" [] subset: RO:0002259 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 -holds_over_chain: RO:0002203 part_of +holds_over_chain: develops_into part_of is_a: has_potential_to_developmentally_contribute_to ! has potential to developmentally contribute to is_a: RO:0002286 ! developmentally succeeded by @@ -13817,7 +13818,7 @@ range: BFO:0000004 ! independent continuant is_transitive: true is_a: has_developmental_contribution_from ! has developmental contribution from is_a: RO:0002258 ! developmentally preceded by -inverse_of: RO:0002203 ! develops into +inverse_of: develops_into ! develops into [Typedef] id: develops_from_part_of @@ -13844,6 +13845,22 @@ domain: UBERON:0001062 ! anatomical entity holds_over_chain: directly_develops_from located_in is_a: RO:0002258 ! developmentally preceded by +[Typedef] +id: develops_into +name: develops into +namespace: uberon +def: "inverse of develops from" [] +subset: RO:0002259 +xref: RO:0002203 +property_value: IAO:0000114 IAO:0000125 +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 +property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172 +property_value: IAO:0000117 https://orcid.org/0000-0003-1980-3228 +is_transitive: true +is_a: has_potential_to_develop_into ! has potential to develop into +is_a: RO:0002286 ! developmentally succeeded by +is_a: RO:0002388 ! has potential to directly develop into + [Typedef] id: directly_develops_from name: directly develops from @@ -14178,7 +14195,7 @@ is_a: RO:0002479 ! has part that occurs in id: has_high_plasma_membrane_amount name: obsolete has_high_plasma_membrane_amount def: "OBSOLETE A relation between a cell and molecule or complex such that every instance of the cell has a high number of instances of that molecule expressed on the cell surface. For the formal definition, see Masci et al (PMID:19243617)." [PMID:19243617] -comment: Replaced with RO:0015015, see https://github.com/obophenotype/cell-ontology/issues/1481 +property_value: term_tracker_item https://github.com/obophenotype/cell-ontology/issues/1481 is_obsolete: true replaced_by: RO:0015015 @@ -14205,7 +14222,7 @@ inverse_of: input_of ! input of id: has_low_plasma_membrane_amount name: obsolete has_low_plasma_membrane_amount def: "OBSOLETE A relation between a cell and molecule or complex such that every instance of the cell has a low number of instances of that molecule expressed on the cell surface. For the formal definition, see Masci et al (PMID:19243617)." [PMID:19243617] -comment: Replaced with RO:0015016, see https://github.com/obophenotype/cell-ontology/issues/1481 +property_value: term_tracker_item https://github.com/obophenotype/cell-ontology/issues/1481 is_obsolete: true replaced_by: RO:0015016 @@ -15591,21 +15608,21 @@ is_a: develops_from ! develops from id: transitively_anteriorly_connected_to name: transitively anteriorly connected to namespace: uberon -def: "." [http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern] +property_value: seeAlso "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" xsd:anyURI is_transitive: true [Typedef] id: transitively_distally_connected_to name: transitively distally connected to namespace: uberon -def: "." [http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern] +property_value: seeAlso "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" xsd:anyURI is_transitive: true [Typedef] id: transitively_proximally_connected_to name: transitively proximally connected to namespace: uberon -def: "." [http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern] +property_value: seeAlso "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" xsd:anyURI is_transitive: true [Typedef] diff --git a/subsets/general_cell_types_upper_slim.owl b/subsets/general_cell_types_upper_slim.owl index af2ba343e..48fbe975e 100644 --- a/subsets/general_cell_types_upper_slim.owl +++ b/subsets/general_cell_types_upper_slim.owl @@ -18,6 +18,7 @@ xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#" xmlns:skos="http://www.w3.org/2004/02/skos/core#" xmlns:swrl="http://www.w3.org/2003/11/swrl#" + xmlns:sssom="https://w3id.org/sssom/" xmlns:swrla="http://swrl.stanford.edu/ontologies/3.3/swrla.owl#" xmlns:swrlb="http://www.w3.org/2003/11/swrlb#" xmlns:terms="http://purl.org/dc/terms/" @@ -29,8 +30,8 @@ xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#" xmlns:ncbitaxon="http://purl.obolibrary.org/obo/ncbitaxon#"> - - 2024-01-04 + + 2024-02-13 @@ -315,6 +316,14 @@ Annotations: IAO_0000424 "http://purl.obolibrary.org/obo/BFO_0000051 some ( + + + + + + + + @@ -337,6 +346,14 @@ Annotations: IAO_0000424 "http://purl.obolibrary.org/obo/BFO_0000051 some ( + + + + + + + + @@ -846,25 +863,25 @@ WHERE { - + - + - + - + - + - + @@ -1071,14 +1088,6 @@ WHERE { - - - - - - - - @@ -1103,14 +1112,6 @@ WHERE { - - - - - - - - @@ -1942,6 +1943,24 @@ WHERE { + + + + + + + + + + + + + + + + + + - - - - - - - - - - - - - - - - - - - - - A nucleus size quality which is relatively high compared to the amount of cytoplasm present in the same cell. - - 2009-12-23T10:53:24Z - increased nucleus size - - - - - A nucleus size quality which is relatively high compared to the amount of cytoplasm present in the same cell. - GOC:tfm - - - - @@ -15340,7 +15381,7 @@ For example, A and B may be gene products and binding of B by A positively regul - A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex). + A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex). https://github.com/geneontology/go-ontology/issues/17729 GO:0008372 NIF_Subcellular:sao1337158144 @@ -15361,7 +15402,7 @@ For example, A and B may be gene products and binding of B by A positively regul - A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex). + A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex). GOC:pdt @@ -15391,8 +15432,8 @@ For example, A and B may be gene products and binding of B by A positively regul + - Note that this term is intended to annotate gene products that are not attached to the cell surface. For gene products from multicellular organisms which are secreted from a cell but retained within the organism (i.e. released into the interstitial fluid or blood), consider the cellular component term 'extracellular space ; GO:0005615'. extracellular region @@ -15409,32 +15450,32 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + A protein complex consisting of three collagen chains assembled into a left-handed triple helix. These trimers typically assemble into higher order structures. Wikipedia:Collagen cellular_component GO:0005581 collagen trimer - + - + - + PMID:12382326 - + PMID:12382326 @@ -15625,8 +15666,8 @@ For example, A and B may be gene products and binding of B by A positively regul + - Chromosomes include parts that are not part of the chromatin. Examples include the kinetochore. chromosome @@ -15692,8 +15733,8 @@ For example, A and B may be gene products and binding of B by A positively regul + - cytoplasm @@ -15822,8 +15863,8 @@ For example, A and B may be gene products and binding of B by A positively regul + - plasma membrane @@ -15920,8 +15961,8 @@ For example, A and B may be gene products and binding of B by A positively regul + - DNA recombination @@ -15953,7 +15994,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Note that this term should not be used for direct annotation. It should be possible to make a more specific annotation to one of the children of this term, for e.g. to transmembrane transport, to microtubule-based transport or to vesicle-mediated transport. transport @@ -18047,8 +18088,8 @@ For example, A and B may be gene products and binding of B by A positively regul + - Note that a signal is any variable property or parameter that serves to convey information, and may be a physical entity such as a gene product or small molecule, a photon, or a change in state such as movement or voltage change. signaling @@ -18201,7 +18242,7 @@ For example, A and B may be gene products and binding of B by A positively regul cell projection organization and biogenesis cell surface structure organization and biogenesis GO:0030030 - + cell projection organization @@ -18746,7 +18787,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + extracellular matrix @@ -19709,7 +19750,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + cell projection @@ -19796,6 +19837,7 @@ For example, A and B may be gene products and binding of B by A positively regul The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. + https://github.com/geneontology/go-ontology/issues/26424 GO:0034960 GO:0043283 GO:0044259 @@ -19805,6 +19847,7 @@ For example, A and B may be gene products and binding of B by A positively regul multicellular organismal macromolecule metabolic process biological_process GO:0043170 + macromolecule metabolic process @@ -19854,7 +19897,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + organelle @@ -20180,7 +20223,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. GO:0002226 Wikipedia:Innate_immune_system @@ -21006,9 +21049,11 @@ For example, A and B may be gene products and binding of B by A positively regul The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. + https://github.com/geneontology/go-ontology/issues/26424 development of an anatomical structure biological_process GO:0048856 + @@ -21056,7 +21101,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + cell motility @@ -21385,7 +21430,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. response to stimulus @@ -21969,7 +22014,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + membrane organization @@ -22201,6 +22246,7 @@ For example, A and B may be gene products and binding of B by A positively regul The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon. + https://github.com/geneontology/go-ontology/issues/26424 mah 2010-03-08T03:32:18Z organic molecular entity metabolic process @@ -22208,6 +22254,7 @@ For example, A and B may be gene products and binding of B by A positively regul organic substance metabolism biological_process GO:0071704 + organic substance metabolic process @@ -22261,7 +22308,7 @@ For example, A and B may be gene products and binding of B by A positively regul - The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures. + The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures. mah 2010-10-04T01:51:47Z cellular_component @@ -22272,7 +22319,7 @@ For example, A and B may be gene products and binding of B by A positively regul - The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures. + The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures. GOC:pdt @@ -22491,7 +22538,7 @@ For example, A and B may be gene products and binding of B by A positively regul biological_process GO:0098542 - + defense response to other organism @@ -23161,6 +23208,7 @@ For example, A and B may be gene products and binding of B by A positively regul A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex but below that of an anatomical system. Or, a substance produced by a cellular organism with granularity above the level of a protein complex. https://github.com/geneontology/go-ontology/issues/24200 + https://github.com/geneontology/go-ontology/issues/26424 kmv 2019-08-12T18:01:37Z cellular_component @@ -23341,6 +23389,27 @@ For example, A and B may be gene products and binding of B by A positively regul + + + + + Reactions triggered in response to the presence of a symbiont that act to protect or prevent damage to the host. + https://github.com/geneontology/go-ontology/issues/20261 + pg + 2020-11-11T17:19:06Z + biological_process + GO:0140546 + defense response to symbiont + + + + + Reactions triggered in response to the presence of a symbiont that act to protect or prevent damage to the host. + GOC:pg + + + + @@ -24419,57 +24488,6 @@ For example, A and B may be gene products and binding of B by A positively regul - - - - - quality - PATO:0000068 - TODO: define this or obsolete it and move children somewhere else. - qualitative - - - - - - - - - A quality inhering in a bearer by virtue of the whether the bearer differs from normal or average. - quality - PATO:0000069 - - deviation (from_normal) - - - - - A quality inhering in a bearer by virtue of the whether the bearer differs from normal or average. - PATOC:GVG - - - - - - - - - A morphology quality inhering in a bearer by virtue of the bearer's physical magnitude. - quality - PATO:0000117 - - - size - - - - - A morphology quality inhering in a bearer by virtue of the bearer's physical magnitude. - WordNet:WordNet - - - - @@ -24521,67 +24539,6 @@ For example, A and B may be gene products and binding of B by A positively regul - - - - - A quality inhering in a bearer by virtue of the bearer's exhibiting no deviation from normal or average. - - quality - average - PATO:0000461 - - - - normal - - - - - A quality inhering in a bearer by virtue of the bearer's exhibiting no deviation from normal or average. - PATOC:GVG - - - - - - - - - - - - - - - - - - - - - A size quality which is relatively high. - - PATO:0001202 - quality - big - enlarged - expanded - great - large - PATO:0000586 - - increased size - - - - - A size quality which is relatively high. - PATOC:GVG - - - - @@ -25172,77 +25129,6 @@ For example, A and B may be gene products and binding of B by A positively regul - - - - - - - - - - - - - - - - - - - - - - A quality that has a value that is increased compared to normal or average. - - - 2011-06-16T06:39:43Z - quality - PATO:0002300 - increased quality - - - - - A quality that has a value that is increased compared to normal or average. - PATOC:GVG - - - - - - - - - - - - - - - - - - - - - A quality of an object that has a value that is increased compared to normal or average. - - - 2011-06-16T06:54:01Z - quality - PATO:0002305 - increased object quality - - - - - A quality of an object that has a value that is increased compared to normal or average. - PATOC:GVG - - - - @@ -25372,6 +25258,28 @@ For example, A and B may be gene products and binding of B by A positively regul + + + + + A quality inhering in a cell by virtue of the cell having a high nuclear/cytoplasmic ratio. + http://orcid.org/0000-0001-5208-3432 + high N:C ratio + quality + PATO:0040072 + A high nuclear/cytolasmic ratio is 70% or higher. + high nuclear/cytoplasmic ratio + + + + + A quality inhering in a cell by virtue of the cell having a high nuclear/cytoplasmic ratio. + Wikipedia:NC_ratio&oldid=931936284 + http://lymerick.net/blood-cells.pdf + + + + @@ -27700,6 +27608,12 @@ For example, A and B may be gene products and binding of B by A positively regul https://github.com/obophenotype/uberon/issues/549 https://orcid.org/0000-0002-6601-2165 + + + + FBbt:00005155 + + @@ -27807,8 +27721,8 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + @@ -27859,11 +27773,11 @@ For example, A and B may be gene products and binding of B by A positively regul tendon http://upload.wikimedia.org/wikipedia/commons/3/3c/Achilles-tendon.jpg - + - + @@ -27876,13 +27790,13 @@ For example, A and B may be gene products and binding of B by A positively regul - + OG - + AEO @@ -27936,7 +27850,7 @@ For example, A and B may be gene products and binding of B by A positively regul tendo Wikipedia:Tendon - + @@ -28000,6 +27914,12 @@ For example, A and B may be gene products and binding of B by A positively regul A tube shaped portion of tissue lined with epithelial cells that collects secretions and routes them to their destination[ZFA:0005171]. ZFA:0005171 + + + + FBbt:00100314 + + @@ -28121,6 +28041,12 @@ For example, A and B may be gene products and binding of B by A positively regul Material anatomical entity that is a single connected structure with inherent 3D shape generated by coordinated expression of the organism's own genome. CARO:0000003 + + + + FBbt:00007001 + + @@ -28730,7 +28656,9 @@ For example, A and B may be gene products and binding of B by A positively regul IDOMAL:0000302 - https://orcid.org/0000-0003-4423-4370 + + + https://github.com/biopragmatics/biomappings @@ -28755,7 +28683,7 @@ For example, A and B may be gene products and binding of B by A positively regul zygotum Wikipedia:Zygote - + @@ -28879,7 +28807,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -28915,14 +28843,14 @@ For example, A and B may be gene products and binding of B by A positively regul gastrula stage - + - + BILS @@ -29200,6 +29128,12 @@ For example, A and B may be gene products and binding of B by A positively regul in FMA, the tongue, palate etc are part of the mouth which is itself a subdivision of the face. ZFA includes a separate class 'oral region' which is part of the mouth, but excludes tongue and lips FMA + + + + FBbt:00003126 + + @@ -29207,14 +29141,14 @@ For example, A and B may be gene products and binding of B by A positively regul BTO:0004698 FMA:49184 FMA:TA - + cavital oralis Wikipedia:Mouth - + @@ -29474,7 +29408,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -29516,14 +29450,14 @@ For example, A and B may be gene products and binding of B by A positively regul organism substance - + - + this relationship may be too strong and may be weakened in future @@ -29532,6 +29466,12 @@ For example, A and B may be gene products and binding of B by A positively regul Material anatomical entity in a gaseous, liquid, semisolid or solid state; produced by anatomical structures or derived from inhaled and ingested substances that have been modified by anatomical structures as they pass through the body. http://orcid.org/0000-0001-9114-8737 + + + + FBbt:00007019 + + @@ -29610,6 +29550,12 @@ For example, A and B may be gene products and binding of B by A positively regul Non-material anatomical entity of three dimensions, that is generated by morphogenetic or other physiologic processes; is surrounded by one or more anatomical structures; contains one or more organism substances or anatomical structures. http://orcid.org/0000-0001-9114-8737 + + + + FBbt:00007017 + + @@ -29659,6 +29605,12 @@ For example, A and B may be gene products and binding of B by A positively regul Anatomical entity that has mass. http://orcid.org/0000-0001-9114-8737 + + + + FBbt:00007016 + + @@ -29695,6 +29647,12 @@ For example, A and B may be gene products and binding of B by A positively regul Anatomical entity that has no mass. http://orcid.org/0000-0001-9114-8737 + + + + FBbt:00007015 + + @@ -29780,11 +29738,19 @@ For example, A and B may be gene products and binding of B by A positively regul system GO:0048731 + + + + FBbt:00004856 + + IDOMAL:0002460 - https://orcid.org/0000-0003-4423-4370 + + + https://github.com/biopragmatics/biomappings @@ -29883,6 +29849,12 @@ For example, A and B may be gene products and binding of B by A positively regul VHOG:0000671 WBbt:0007833 + + + + FBbt:00000001 + + @@ -29986,6 +29958,12 @@ For example, A and B may be gene products and binding of B by A positively regul CARO:DOS http://orcid.org/0000-0001-9114-8737 + + + + FBbt:00007009 + + @@ -30053,6 +30031,12 @@ For example, A and B may be gene products and binding of B by A positively regul Anatomical structure that consists of cell parts and cell substances and together does not constitute a cell or a tissue. http://orcid.org/0000-0001-9114-8737 + + + + FBbt:00007013 + + @@ -30072,7 +30056,6 @@ For example, A and B may be gene products and binding of B by A positively regul FBbt:00007277 - IDOMAL:0002461 VHOG:0001737 uberon UBERON:0000477 @@ -30089,8 +30072,8 @@ For example, A and B may be gene products and binding of B by A positively regul - IDOMAL:0002461 - https://orcid.org/0000-0003-4423-4370 + FBbt:00007277 + @@ -30154,6 +30137,12 @@ For example, A and B may be gene products and binding of B by A positively regul http://orcid.org/0000-0001-9114-8737 https://cedar.bio.indiana.edu/trac/env/ontologies/ticket/279 + + + + FBbt:00005835 + + @@ -30236,6 +30225,12 @@ For example, A and B may be gene products and binding of B by A positively regul Multicellular anatomical structure that consists of many cells of one or a few types, arranged in an extracellular matrix such that their long-range organisation is at least partly a repetition of their short-range organisation. CARO:0000043 + + + + FBbt:00007003 + + @@ -30303,6 +30298,12 @@ For example, A and B may be gene products and binding of B by A positively regul CARO:0000055 http://orcid.org/0000-0001-9114-8737 + + + + FBbt:00007010 + + @@ -30349,7 +30350,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -30393,14 +30394,14 @@ For example, A and B may be gene products and binding of B by A positively regul epithelium https://upload.wikimedia.org/wikipedia/commons/8/8f/Illu_epithelium.jpg - + - + http://palaeos.com/metazoa/porifera/homoscleromorpha.html @@ -30420,6 +30421,12 @@ For example, A and B may be gene products and binding of B by A positively regul ISBN:978-0030259821 Ruppert EE, Fox RS, Barnes RD, Invertebrate zoology: a functional evolutionary approach (2003) p.59 http://bgee.unil.ch/ + + + + FBbt:00007005 + + @@ -30654,11 +30661,19 @@ For example, A and B may be gene products and binding of B by A positively regul Obsoleted in ZFA. Note that embryo is not classified as an embryonic structure - an embryonic structure is only the parts of an embryo ZFA + + + + FBbt:00000052 + + IDOMAL:0000646 - https://orcid.org/0000-0003-4423-4370 + + + https://github.com/biopragmatics/biomappings @@ -30745,6 +30760,12 @@ For example, A and B may be gene products and binding of B by A positively regul embryonic tissue FMA:69069 + + + + FBbt:00000110 + + @@ -30783,7 +30804,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Primary germ layer that is the outer of the embryo's three germ layers and gives rise to epidermis and neural tissue. Primary germ layer that is the outer of the embryonic germ layers and gives rise to epidermis and neural tissue.[AAO] The Bilateria are triploblastic (with true endoderm, mesoderm, and ectoderm) (...).[well established][VHOG] @@ -30821,14 +30842,14 @@ For example, A and B may be gene products and binding of B by A positively regul ectoderm http://upload.wikimedia.org/wikipedia/commons/1/19/Gray32.png - + - + Bgee:AN @@ -30856,6 +30877,12 @@ For example, A and B may be gene products and binding of B by A positively regul ISBN:978-0878932504 Gilbert SF, Developmental Biology (2006) Limb development and evolution, p.722 http://bgee.unil.ch/ + + + + FBbt:00000111 + + @@ -30881,7 +30908,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Primary germ layer that lies remote from the surface of the embryo and gives rise to internal tissues such as gut. The Bilateria are triploblastic (with true endoderm, mesoderm, and ectoderm) (...).[well established][VHOG] endodermal @@ -30918,14 +30945,14 @@ For example, A and B may be gene products and binding of B by A positively regul http://upload.wikimedia.org/wikipedia/commons/c/c0/Endoderm2.png http://upload.wikimedia.org/wikipedia/commons/d/df/Gray10.png - + - + Bgee:AN @@ -30944,6 +30971,12 @@ For example, A and B may be gene products and binding of B by A positively regul ISBN:978-0878932504 Gilbert SF, Developmental Biology (2006) Limb development and evolution, p.722 http://bgee.unil.ch/ + + + + FBbt:00000125 + + @@ -30970,7 +31003,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + The middle germ layer of the embryo, between the endoderm and ectoderm. Primary germ layer that is the middle of the embryonic germ layers.[AAO] @@ -31015,7 +31048,7 @@ For example, A and B may be gene products and binding of B by A positively regul mesoderm http://upload.wikimedia.org/wikipedia/commons/e/e8/Mesoderm.png - + @@ -31028,7 +31061,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Bgee:AN @@ -31062,6 +31095,12 @@ For example, A and B may be gene products and binding of B by A positively regul sponges do not seem to have a mesoderm and accordingly Amphimedon lacks transcription factors involved in mesoderm development (Fkh, Gsc, Twist, Snail)[http://www.nature.com/nature/journal/v466/n7307/full/nature09201.html]. Mesoderm may not be homologous across verteberates https://github.com/obophenotype/uberon/wiki/The-neural-crest + + + + FBbt:00000126 + + @@ -31171,6 +31210,12 @@ For example, A and B may be gene products and binding of B by A positively regul stomodeal-hypophyseal primordium XAO:0000269 + + + + FBbt:00000439 + + @@ -31308,6 +31353,12 @@ For example, A and B may be gene products and binding of B by A positively regul DOI:10.1073/pnas.0812138106 Markov GV, Tavares R, Dauphin-Villemant C, Demeneix BA, Baker ME, Laudet V, Independent elaboration of steroid hormone signaling pathways in metazoans. PNAS (2009) http://bgee.unil.ch/ + + + + FBbt:00005068 + + @@ -31333,8 +31384,8 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + @@ -31370,24 +31421,24 @@ For example, A and B may be gene products and binding of B by A positively regul eye - + - + - + PMID:21062451 - + PMID:21062451 @@ -31396,6 +31447,12 @@ For example, A and B may be gene products and binding of B by A positively regul An organ that detects light. https://orcid.org/0000-0002-6601-2165 + + + + FBbt:00005162 + + @@ -31620,6 +31677,12 @@ For example, A and B may be gene products and binding of B by A positively regul many anatomy ontologies consider gastrointestinal system synonymous with digestive system. here we follow MA in dividing digestive system into gastrointestinal and hepatobiliary. hepatobiliary includes the liver and biliary tract. species-specific AO classes are categorized according to whether liver is included. For example, XAO includes liver as part of XAO:0000125 alimentary system, so we assume this class is the more generic class MA + + + + FBbt:00005055 + + @@ -31663,6 +31726,7 @@ For example, A and B may be gene products and binding of B by A positively regul We should divest ourselves of the view that earlier vertebrate groups were 'on their way' to becoming mammals, as clearly they were not such visionaries. Neither were their systems 'imperfect' as earlier anatomists thought. Instead, their circulatory systems served them well to address the ecological demands arising from their lifestyles.[well established][VHOG] AAO:0000959 CALOHA:TS-2103 + MESH:D002319 VHOG:0001248 Wikipedia:Circulatory_system uberon @@ -31710,12 +31774,19 @@ For example, A and B may be gene products and binding of B by A positively regul ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.493 http://bgee.unil.ch/ + + + + MESH:D002319 + + https://github.com/biopragmatics/biomappings + systema cardiovasculare Wikipedia:Circulatory_system - + @@ -31796,7 +31867,7 @@ For example, A and B may be gene products and binding of B by A positively regul musculi FMA:32558 FMA:TA - + @@ -31856,6 +31927,7 @@ For example, A and B may be gene products and binding of B by A positively regul The nervous system is an organ system containing predominantly neuron and glial cells. In bilaterally symmetrical organism, it is arranged in a network of tree-like structures connected to a central body. The main functions of the nervous system are to regulate and control body functions, and to receive sensory input, process this information, and generate behavior [CUMBO]. + A regulatory system of the body that consists of neurons and neuroglial cells. The nervous system is divided into two parts, the central nervous system (CNS) and the peripheral nervous system (PNS). (Source: BioGlossary, www.Biology-Text.com)[TAO] Anatomical system consisting of nerve bodies and nerve fibers which regulate the response of the body to external and internal stimuli.[AAO] Nervous systems evolved in the ancestor of Eumetazoa.[well established][VHOG] @@ -31895,6 +31967,7 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0001016 + @@ -31952,6 +32025,12 @@ For example, A and B may be gene products and binding of B by A positively regul ISBN:978-0198566694 Schmidt-Rhaesa A, The evolution of organ systems (2007) p.117 http://bgee.unil.ch/ + + + + FBbt:00005093 + + @@ -31975,7 +32054,7 @@ For example, A and B may be gene products and binding of B by A positively regul systema nervosum Wikipedia:Nervous_system - + @@ -31997,9 +32076,10 @@ For example, A and B may be gene products and binding of B by A positively regul - + The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the neural tube derivatives: the brain and spinal cord. In invertebrates it includes central ganglia plus nerve cord. + Part of the nervous system which includes the brain and spinal cord.[AAO] The brain and spinal cord. Kimmel et al, 1995.[TAO] The central nervous system (CNS) is the part of the nervous system which includes the brain, spinal cord, and nerve cell layer of the retina (CUMBO). @@ -32039,12 +32119,13 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0001017 + central nervous system - + @@ -32058,7 +32139,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Bgee:AN @@ -32109,6 +32190,12 @@ For example, A and B may be gene products and binding of B by A positively regul ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.28 (reference 1), ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.165 (reference 2), DOI:10.1016/j.cell.2007.02.040 Denes AS, Jekely G, Steinmetz PRH, Raible F, Snyman H, Prud'homme B, Ferrier DEK, Balavoine G and Arendt D, Molecular architecture of annelid nerve cord supports common origin of nervous system centralization in Bilateria. Cell (2007) (reference 3) http://bgee.unil.ch/ + + + + FBbt:00005094 + + @@ -32128,7 +32215,7 @@ For example, A and B may be gene products and binding of B by A positively regul systema nervosum centrale FMA:55675 FMA:TA - + @@ -32220,13 +32307,19 @@ For example, A and B may be gene products and binding of B by A positively regul DOI:10.1073/pnas.97.9.4449 Shimeld SM and Holland PW. Vertebrate innovations. PNAS (2000) http://bgee.unil.ch/ + + + + FBbt:00007692 + + organa sensuum FMA:75259 FMA:TA - + @@ -32252,7 +32345,7 @@ For example, A and B may be gene products and binding of B by A positively regul organa sensuum Wikipedia:Sensory_system - + @@ -32361,6 +32454,14 @@ For example, A and B may be gene products and binding of B by A positively regul The mature structure of the neural tube exists when the tube has been segmented into the forebrain, midbrain, hindbrain and spinal cord regions. In addition neural crest has budded away from the epithelium GO:0021915 + + + + MESH:D054259 + + + https://github.com/biopragmatics/biomappings + @@ -32372,7 +32473,7 @@ For example, A and B may be gene products and binding of B by A positively regul tubus neuralis Wikipedia:Neural_tube - + @@ -32415,6 +32516,12 @@ For example, A and B may be gene products and binding of B by A positively regul FMA:62955 http://orcid.org/0000-0001-9114-8737 + + + + FBbt:10000000 + + @@ -32926,7 +33033,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Skeletal element that is composed of bone tissue. @@ -32976,14 +33083,14 @@ For example, A and B may be gene products and binding of B by A positively regul bone element - + - + VSAO-modified @@ -33094,7 +33201,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + A tube extending from the mouth to the anus. @@ -33115,6 +33222,7 @@ For example, A and B may be gene products and binding of B by A positively regul FBbt:00003125 FMA:45615 MA:0000917 + MESH:D041981 NCIT:C34082 TAO:0000112 TGMA:0001819 @@ -33136,14 +33244,14 @@ For example, A and B may be gene products and binding of B by A positively regul digestive tract - + - + NCBIBook:NBK10107 @@ -33196,6 +33304,19 @@ For example, A and B may be gene products and binding of B by A positively regul we place the MA and EMAPA class here, although the intent is probably a smaller region. See https://github.com/obophenotype/uberon/issues/509 MA + + + + FBbt:00003125 + + + + + + MESH:D041981 + + https://github.com/biopragmatics/biomappings + @@ -33474,6 +33595,12 @@ For example, A and B may be gene products and binding of B by A positively regul in FMA embryo is_a embryonic structure FMA + + + + FBbt:00004208 + + @@ -33734,7 +33861,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -33770,14 +33897,14 @@ For example, A and B may be gene products and binding of B by A positively regul musculoskeletal system - + - + check ctenophore @@ -33840,9 +33967,9 @@ For example, A and B may be gene products and binding of B by A positively regul - - - + + + @@ -33897,15 +34024,15 @@ For example, A and B may be gene products and binding of B by A positively regul notochord http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + - + - + @@ -33924,19 +34051,19 @@ For example, A and B may be gene products and binding of B by A positively regul - + http://tolweb.org/Chordata/2499 - + ZFA - + EHDAA2 @@ -34011,7 +34138,7 @@ For example, A and B may be gene products and binding of B by A positively regul notochorda Wikipedia:Notochord - + @@ -34021,8 +34148,8 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + Somites are spheres of epithelial cells that form sequentially along the anterior-posterior axis of the embryo through mesenchymal to epithelial transition of the presomitic mesoderm. EDITOR_NOTE currently classified as an epithelial vesicle, consistent with EHDAA2 and https://github.com/obophenotype/uberon/wiki/The-neural-crest. Consider making 'somitic mesoderm' a separate term and correlate with regionalization processes. Consider moving ZFA term to 'trunk somite' as it is part of the trunk @@ -34068,11 +34195,11 @@ For example, A and B may be gene products and binding of B by A positively regul somite http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + - + @@ -34085,13 +34212,13 @@ For example, A and B may be gene products and binding of B by A positively regul - + GOTAX:0000352 - + ZFA @@ -34194,7 +34321,7 @@ For example, A and B may be gene products and binding of B by A positively regul somitus Wikipedia:Somite - + @@ -34268,12 +34395,12 @@ For example, A and B may be gene products and binding of B by A positively regul - - - - + + + + A specialized region of ectoderm found between the neural ectoderm (neural plate) and non-neural ectoderm and composed of highly migratory pluripotent cells that delaminate in early embryonic development from the dorsal neural tube and give rise to an astounding variety of differentiated cell types[MP]. EDITOR_NOTE consider including subclasses for pre- and post- migratory (e.g. sheets/paths/streams). @@ -34313,66 +34440,66 @@ For example, A and B may be gene products and binding of B by A positively regul http://upload.wikimedia.org/wikipedia/commons/5/5f/Gray644.png https://upload.wikimedia.org/wikipedia/commons/8/8f/Neural_Crest.png - + - + - + - + - + - + - + XAO https://github.com/obophenotype/uberon/wiki/The-neural-crest - + Hall and others restrict NC to vertebrates but we opt for a less restrictive constraint to avoid inconsistencies when areas such as P1 area of pallium in hagfishes inherit cell lineage from telecephalon-contributing NC cells ISBN:0073040584 - + BTO - + PMID:11523831 - + pre migratory https://github.com/obophenotype/uberon/wiki/The-neural-crest - + PMID:11523831 @@ -34440,7 +34567,7 @@ For example, A and B may be gene products and binding of B by A positively regul crista neuralis Wikipedia:Neural_crest - + @@ -34513,6 +34640,12 @@ For example, A and B may be gene products and binding of B by A positively regul DOI:10.1046/j.1469-7580.2001.19910133.x Graham A. The development and evolution of the pharyngeal arches. J Anat (2001) http://bgee.unil.ch/ + + + + FBbt:00001057 + + @@ -34524,7 +34657,7 @@ For example, A and B may be gene products and binding of B by A positively regul epithelium tubi neuralis; neuroectoderma Wikipedia:Neuroectoderm - + @@ -34610,7 +34743,7 @@ For example, A and B may be gene products and binding of B by A positively regul glandula exocrina Wikipedia:Exocrine_gland - + @@ -34697,7 +34830,7 @@ For example, A and B may be gene products and binding of B by A positively regul glandulae endocrinae Wikipedia:Endocrine_gland - + @@ -34727,7 +34860,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -34785,14 +34918,14 @@ For example, A and B may be gene products and binding of B by A positively regul bone marrow http://upload.wikimedia.org/wikipedia/commons/7/74/Gray72-en.svg - + - + FMA MA @@ -34825,7 +34958,7 @@ For example, A and B may be gene products and binding of B by A positively regul medulla ossea BTO:0000141 FMA:9608 - + @@ -34833,7 +34966,7 @@ For example, A and B may be gene products and binding of B by A positively regul medulla ossium BTO:0000141 Wikipedia:Bone_marrow - + @@ -35063,14 +35196,14 @@ For example, A and B may be gene products and binding of B by A positively regul - + - + Anatomical system that is involved in the production of hematopoietic cells. @@ -35116,24 +35249,24 @@ For example, A and B may be gene products and binding of B by A positively regul hematopoietic system - + - + - + FMA - + definitional @@ -35423,6 +35556,12 @@ For example, A and B may be gene products and binding of B by A positively regul MGI:csmith MP:0002163 + + + + FBbt:00100317 + + @@ -35447,7 +35586,7 @@ For example, A and B may be gene products and binding of B by A positively regul glandula BTO:0000522 Wikipedia:Gland - + @@ -35519,7 +35658,7 @@ For example, A and B may be gene products and binding of B by A positively regul epiblastus Wikipedia:Epiblast - + @@ -35599,7 +35738,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Unsegmented field of paraxial mesoderm present posterior to the most recently formed somite pair, from which somites will form. Unsegmented field of paraxial mesoderm present posterior to the most recently formed somite pair, from which somites will form. Kimmel et al, 1995.[TAO] It is reasonable to assume that the proximate invertebrate ancestor of the vertebrates had an amphioxus-like tail bud in its larval stage. This archetypal tail bud would have (...) (3) lacked any component of mesenchyme cells, (4) budded off new mesodermal segments directly, without any intervening zone of presomitic mesoderm (...). Then, early in vertebrate evolution, epithelium-to-mesenchyme interconversions (and the gene networks for effecting them) became prominent features of development. (...) In any case, conspicuous mesenchymal components tended to be added to the vertebrate tail bud itself. In addition, a mesenchymatous presomitic mesoderm (not a part of the tail bud proper) came to intervene between the tail bud and the forming somites.[well established][VHOG] @@ -35624,14 +35763,14 @@ For example, A and B may be gene products and binding of B by A positively regul presomitic mesoderm - + - + Bgee:AN @@ -35861,9 +36000,9 @@ For example, A and B may be gene products and binding of B by A positively regul - - - + + + A region of embryonic ectodermal cells that lie directly above the notochord. During neurulation, they change shape and produce an infolding of the neural plate (the neural fold) that then seals to form the neural tube[XAO]. The earliest recognizable dorsal ectodermal primordium of the central nervous system present near the end of gastrulation before infolding to form the neural keel; consists of a thickened pseudostratified epithelium[ZFA]. The earliest recognizable dorsal ectodermal primordium of the central nervous system present near the end of gastrulation before infolding to form the neural keel; consists of a thickened pseudostratified epithelium. Kimmel et al, 1995.[TAO] (...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord that is located dorsal to the notochord (...).[well established][VHOG] @@ -35895,34 +36034,34 @@ For example, A and B may be gene products and binding of B by A positively regul neural plate https://upload.wikimedia.org/wikipedia/commons/8/8f/Neural_Crest.png - + - + - + - + GOTAX:0000352 - + Wikipedia - + Bgee:AN @@ -35953,6 +36092,14 @@ For example, A and B may be gene products and binding of B by A positively regul ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.28 http://bgee.unil.ch/ + + + + MESH:D054258 + + + https://github.com/biopragmatics/biomappings + @@ -35964,7 +36111,7 @@ For example, A and B may be gene products and binding of B by A positively regul lamina neuralis Wikipedia:Neural_plate - + @@ -35987,7 +36134,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube[GO]. Mesoderm lateral to the neural tube and notochord that is divided into cranial and post-cranial portions. The trunk portions further segment into somites.[AAO] Presently, Cephalochordata, Urochordata, and Vertebrata are placed as subphyla of the phylum Chordata, in which the overall organization of embryonic tissues (dorsal hollow nerve cord, ventral digestive tract, axial notochord, and bilateral paraxial mesoderm) is largely conserved. In contrast, the echinoderms and hemichordates are sister groups of the chordates and they lack the notochord and paraxial mesoderm. Thus, the basic mesodermal organization of vertebrates must have appeared first in the common ancestor of the chordates.[well established][VHOG] @@ -36016,7 +36163,7 @@ For example, A and B may be gene products and binding of B by A positively regul paraxial mesoderm http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + @@ -36029,7 +36176,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Bgee:AN @@ -36089,7 +36236,7 @@ For example, A and B may be gene products and binding of B by A positively regul mesoderma paraxiale Wikipedia:Paraxial_mesoderm - + @@ -36101,7 +36248,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -36145,7 +36292,7 @@ For example, A and B may be gene products and binding of B by A positively regul lateral plate mesoderm http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + @@ -36158,7 +36305,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + EHDAA2 VHOG @@ -36233,7 +36380,7 @@ For example, A and B may be gene products and binding of B by A positively regul mesoderma laminae lateralis Wikipedia:Lateral_plate_mesoderm - + @@ -36242,7 +36389,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -36285,7 +36432,7 @@ For example, A and B may be gene products and binding of B by A positively regul myotome http://upload.wikimedia.org/wikipedia/commons/9/96/Gray65.png - + @@ -36298,7 +36445,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + EHDAA2-abduced @@ -36344,7 +36491,7 @@ For example, A and B may be gene products and binding of B by A positively regul myotomus Wikipedia:Myotome - + @@ -36484,7 +36631,7 @@ For example, A and B may be gene products and binding of B by A positively regul mesenchyma Wikipedia:Mesenchyme - + @@ -36499,7 +36646,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + The part of the coelom in the embryo between the somatopleuric and splanchnopleuric mesoderm; the principal body cavities of the trunk (thoracic, abdominal, and pelvic) arise from this embryonic part of the coelom. consider merging with coelom. TODO - add spatial relationships to halves of LPM. Note the OG places XAO and ZFA coelem terms here. editor note: TODO check ZFA, which appears to be a structure present in adults (...) I regard it unlikely that coeloms of all bilaterian animals are comparable and evolved very early. Considering all these questions, few convincing characters concerning the evolution of body cavities remain to be named. (...) A segmental coelom appears to have evolved at least two times, in Annelida and in Myomerata (Acrania and Craniota).[well established][VHOG] @@ -36515,14 +36662,14 @@ For example, A and B may be gene products and binding of B by A positively regul intraembryonic coelom - + - + Wikipedia @@ -36590,6 +36737,12 @@ For example, A and B may be gene products and binding of B by A positively regul GO:0060562 PMID:12526790 + + + + FBbt:00007474 + + @@ -36850,7 +37003,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + The bilaminar epithelium formed from the myotome and dermatome. Epithelial sheet on the external surface of the somite that gives rise to trunk, muscle and dermis. Within the dermomyotome there is also a medio-lateral difference. The central region makes dermis, the mesenchymal connective tissue of the back skin. The medial region (closest to neural tube) makes epaxial muscle, and the lateral region (furthest from neural tube) makes hypaxial muscle[http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=eurekah&part=A66768]. Epithelial sheet on the external surface of the somite that gives rise to trunk, muscle and dermis.[TAO] @@ -36873,7 +37026,7 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0004290 dermomyotome - + @@ -36892,7 +37045,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + EHDAA2 ZFA @@ -37139,6 +37292,12 @@ For example, A and B may be gene products and binding of B by A positively regul We explicitly merge the NCITA terms here NCIT + + + + FBbt:00005317 + + @@ -37218,7 +37377,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + A specialized form of connective tissue in which the extracellular matrix is firm, providing the tissue with resilience, and/or mineralized and that functions in mechanical and structural support.[VSAO]. A specialized form of connective tissue in which the extracellular matrix is firm, providing the tissue with resilience, and/or mineralized and that functions in mechanical and structural support.[VSAO] EMAPA:37744 @@ -37232,7 +37391,7 @@ For example, A and B may be gene products and binding of B by A positively regul Four classes of mineralized tissues are found in vertebrates: bone, cartilage, dentine, and enamel. We think of cartilage and bone as skeletal tissues and of enamel and dentine as dental tissues, but enamel and dentine arose evolutionarily together with bone as skeletal tissues in the dermal skeleton (exoskeleton) of early vertebrates. Scales and teeth of sharks are examples of dermal skeletal elements that are still composed of the three ancient components-enamel, dentine, and bone. Cartilage, on the other hand, provided the basis for the second vertebrate skeletal system, the endoskeleton (Smith and Hall, 1990; Hall, 1998a,b). some invertebrate skeletal tissues have surprisingly bone-like features. Examples include chondrocytes interconnected by cell processes in cephalopod cartilages (Cole and Hall, 2004a,b), and the calcium phosphate layer in the shells of brachiopods (Rodland et al., 2003). However, neither bone nor mineralized cartilage have been found in invertebrates. Editors notes: TODO - develops_from skeletal tissue - + @@ -37245,7 +37404,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + 2012-08-14 VSAO:0000015 VSAO @@ -37284,7 +37443,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Organ consisting of skeletal tissue. Encompasses whole bones, fused bones, cartilaginious elements, teeth, dermal denticles. Organ entity that is typically involved in mechanical support and may have different skeletal tissue compositions at different stages.[VSAO] Organ entity that may have different tissue compositions at different stages and is typically involved in mechanical support.[TAO] @@ -37300,14 +37459,14 @@ For example, A and B may be gene products and binding of B by A positively regul skeletal element - + - + VSAO @@ -37352,7 +37511,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -37391,14 +37550,14 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0004770 articular system - + - + FMA @@ -37518,6 +37677,12 @@ For example, A and B may be gene products and binding of B by A positively regul Anatomical structure that connects two or more adjacent skeletal elements or hardened body parts. http://orcid.org/0000-0002-6601-2165 + + + + FBbt:00005811 + + @@ -37570,6 +37735,12 @@ For example, A and B may be gene products and binding of B by A positively regul A proximal-distal subdivision of the digestive tract. http://orcid.org/0000-0002-6601-2165 + + + + FBbt:00100315 + + @@ -37867,7 +38038,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Mesenchyme that is part of a developing trunk. EFO:0003485 EHDAA2:0002092 @@ -37883,14 +38054,14 @@ For example, A and B may be gene products and binding of B by A positively regul trunk mesenchyme - + - + EHDAA2 @@ -38004,6 +38175,12 @@ For example, A and B may be gene products and binding of B by A positively regul An array of photoreceptors and any supporting cells found in an eye. https://orcid.org/0000-0002-6601-2165 + + + + FBbt:00004200 + + @@ -38034,6 +38211,12 @@ For example, A and B may be gene products and binding of B by A positively regul developing anatomical structure + + + + FBbt:00007006 + + @@ -38171,7 +38354,7 @@ For example, A and B may be gene products and binding of B by A positively regul membrana basalis Wikipedia:Basement_membrane - + @@ -38189,7 +38372,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + The notochordal plate is the dorsal part of the notochordal process when the ventral portion breaks down. It is continuous laterally with the endoderm that composes the roof of the primitive foregut and is in contact dorsally with the neural tube. The folding off of the notochordal plate gives rise to the notochord. TODO - check ordering; awaiting confirmation from JB The notochordal plate is the dorsal part of the notochordal process when the ventral portion breaks down. It is continuous laterally with the endoderm that composes the roof of the primitive foregut and is in contact dorsally with the neural tube. The folding off of the notochordal plate gives rise to the notochord. [Carson_JL, Dehart_DB, Developmental_Dynamics_(1994)_201:_260-278, Gesteland_K_and_Schoenwolf_GC, Inagaki_T, Morphogenesis_of_the_murine_node_and_notochordal_plate, The_prechordal_plate, Vrablic_T, see_Mueller_F_and_O'Rahilly_R, the_rostral_end_of_the_notochord_and_nearby_median_features_in_staged_human_embryos._Cells_Tissues_Organs_(2003)_173:_1-20_and_Sulik_K][VHOG] @@ -38204,7 +38387,7 @@ For example, A and B may be gene products and binding of B by A positively regul notochordal plate - + @@ -38217,7 +38400,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + EHDAA2 @@ -38254,7 +38437,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + A midline cellular cord formed from the migration of mesenchymal cells from the primitive knot. EHDAA2:0001279 EHDAA:224 @@ -38271,14 +38454,14 @@ For example, A and B may be gene products and binding of B by A positively regul The notochordal process grows cranially until it reaches the prechordal plate, the future site of the mouth. In this area the ectoderm is attached directly to the endoderm without intervening mesoderm. This area is known as the oropharyngeal membrane, and it will break down to become the mouth. At the other end of the primitive streak the ectoderm is also fused directly to the endoderm; this is known as the cloacal membrane (proctodeum), or primordial anus. notochordal process - + - + EHDAA2 @@ -38700,7 +38883,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + A hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood or analogs[GO,modified]. note we reserve the subclass 'heart' from the vertebrate multi-chambered heart. 'The first heart-like organ is believed to have appeared 500my ago in an ancestral bilaterian'. Amniotes: four-chambered heart. Amphibians: two atria, one ventricle, pulmonary; fish: single atrium and ventricle; amphioxus: tubular, non-striated, closed, unidirectional; ascidians: tubular, striated, open, bidirectional; arthropods: tubular, open; C elegans: contractile pharynx; Cnideria: striated muscle cells associated with gastrodermis SPD:0000130 @@ -38715,14 +38898,14 @@ For example, A and B may be gene products and binding of B by A positively regul Gene notes: Bmp, Nkx, Gata primary circulatory organ - + - + GO uses blood circulation generically to include the haemolymphatic fluid of arthropods @@ -38812,7 +38995,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -38829,14 +39012,14 @@ For example, A and B may be gene products and binding of B by A positively regul presumptive segmental plate - + - + https://github.com/obophenotype/uberon/wiki/The-neural-crest EDHAA2 @@ -38935,7 +39118,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -38961,7 +39144,7 @@ For example, A and B may be gene products and binding of B by A positively regul presumptive paraxial mesoderm - + @@ -38977,7 +39160,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + https://github.com/obophenotype/uberon/issues/1277 @@ -39026,7 +39209,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Mesenchyme with little extracellular matrix. AEO:0000146 EHDAA2:0003146 @@ -39034,7 +39217,7 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0007524 dense mesenchyme tissue - + @@ -39047,7 +39230,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + AEO @@ -39226,7 +39409,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -39243,14 +39426,14 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0009142 entire embryonic mesenchyme - + - + EHDAA2 @@ -39272,7 +39455,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + EHDAA2:0002094 trunk and cervical paraxial mesenchyme uberon @@ -39280,14 +39463,14 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0009618 trunk paraxial mesoderm - + - + EHDAA2 @@ -39351,6 +39534,12 @@ For example, A and B may be gene products and binding of B by A positively regul An anatomical structure that has more than one cell as a part. CARO:0010000 + + + + FBbt:00100313 + + @@ -39489,12 +39678,14 @@ For example, A and B may be gene products and binding of B by A positively regul + FBbt:00007330 FMA:67509 SCTID:91690000 uberon UBERON:0011216 + organ system subdivision @@ -39510,6 +39701,12 @@ For example, A and B may be gene products and binding of B by A positively regul A subdivision of an anatomical system. http://orcid.org/0000-0002-6601-2165 + + + + FBbt:00007330 + + @@ -39743,7 +39940,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -39768,7 +39965,7 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0011899 epimysium - + @@ -39781,7 +39978,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + FMA @@ -39887,7 +40084,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -39909,7 +40106,7 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0012429 hematopoietic tissue - + @@ -39922,7 +40119,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + defitional @@ -40085,7 +40282,6 @@ For example, A and B may be gene products and binding of B by A positively regul The region of the organism associated with the visceral organs. - Cardinal body part, which consists of a maximal set of diverse subclasses of organ and organ part spatially associated with the vertebral column and ribcage. Examples: There is only one body proper[FMA:231424]. AEO:0000103 BTO:0001489 @@ -40095,7 +40291,6 @@ For example, A and B may be gene products and binding of B by A positively regul body whole body UBERON:0013702 - body proper @@ -40196,6 +40391,7 @@ For example, A and B may be gene products and binding of B by A positively regul A muscle organ that consists of skeletal muscle tissue ensheathed in epimysium, that develops from myotome and that is innervated by some somatic motor neuron. Skeletal muscles are typically attached (via a tendon) to a bone but there are exceptions (e.g. intrinsic tongue muscles). + skeletal muscle AAO:0011099 BTO:0001103 @@ -40218,6 +40414,7 @@ For example, A and B may be gene products and binding of B by A positively regul ZFA:0005277 uberon UBERON:0014892 + skeletal muscle organ, vertebrate @@ -40249,6 +40446,12 @@ For example, A and B may be gene products and binding of B by A positively regul FBC:DOS FBbt:00007278 + + + + FBbt:00007278 + + @@ -40498,7 +40701,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -40521,7 +40724,7 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0016887 entire extraembryonic component - + @@ -40534,7 +40737,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + AEO @@ -40620,7 +40823,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -40628,22 +40831,24 @@ For example, A and B may be gene products and binding of B by A positively regul Added for consistency with MA EMAPA and EHDAA2. See https://github.com/obophenotype/mouse-anatomy-ontology/issues/104 + EHDAA2:0001842 EMAPA:35578 MA:0000165 uberon UBERON:0018254 + skeletal musculature - + - + MA @@ -40756,6 +40961,12 @@ For example, A and B may be gene products and binding of B by A positively regul Material anatomical entity consisting of multiple anatomical structures that are not connected to each other. CARO:0020000 + + + + FBbt:00007276 + + @@ -41184,6 +41395,24 @@ For example, A and B may be gene products and binding of B by A positively regul + + + + + + + + + + + + + + + + + + @@ -41204,6 +41433,16 @@ For example, A and B may be gene products and binding of B by A positively regul + + + + + + + + + + diff --git a/subsets/general_cell_types_upper_slim.tsv b/subsets/general_cell_types_upper_slim.tsv index 75c36b0e2..a0a6dd677 100644 --- a/subsets/general_cell_types_upper_slim.tsv +++ b/subsets/general_cell_types_upper_slim.tsv @@ -1,278 +1,275 @@ ?x ?label -_:B29fb0e95X2D184aX2D4ac6X2D9e6aX2Dbd864e34a507genid1001 -_:B29fb0e95X2D184aX2D4ac6X2D9e6aX2Dbd864e34a507genid1050 -_:B29fb0e95X2D184aX2D4ac6X2D9e6aX2Dbd864e34a507genid1057 -_:B29fb0e95X2D184aX2D4ac6X2D9e6aX2Dbd864e34a507genid1064 -_:B29fb0e95X2D184aX2D4ac6X2D9e6aX2Dbd864e34a507genid1074 -_:B29fb0e95X2D184aX2D4ac6X2D9e6aX2Dbd864e34a507genid1081 -_:B29fb0e95X2D184aX2D4ac6X2D9e6aX2Dbd864e34a507genid1087 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+_:B9ac295d7X2Ded0bX2D4368X2D889cX2D7714613be411genid879 +_:B9ac295d7X2Ded0bX2D4368X2D889cX2D7714613be411genid888 +_:B9ac295d7X2Ded0bX2D4368X2D889cX2D7714613be411genid900 +_:B9ac295d7X2Ded0bX2D4368X2D889cX2D7714613be411genid915 +_:B9ac295d7X2Ded0bX2D4368X2D889cX2D7714613be411genid922 +_:B9ac295d7X2Ded0bX2D4368X2D889cX2D7714613be411genid928 +_:B9ac295d7X2Ded0bX2D4368X2D889cX2D7714613be411genid938 +_:B9ac295d7X2Ded0bX2D4368X2D889cX2D7714613be411genid948 +_:B9ac295d7X2Ded0bX2D4368X2D889cX2D7714613be411genid974 +_:B9ac295d7X2Ded0bX2D4368X2D889cX2D7714613be411genid990 +_:B9ac295d7X2Ded0bX2D4368X2D889cX2D7714613be411genid998 "continuant" "occurrent" "independent continuant" @@ -409,7 +406,6 @@ _:B29fb0e95X2D184aX2D4ac6X2D9e6aX2Dbd864e34a507genid993 "precursor cell" "neutrophillic cytoplasm" "basophilic cytoplasm" - "increased nucleus size" "bone marrow hematopoietic cell" "reproduction" "lytic vacuole" @@ -688,6 +684,7 @@ _:B29fb0e95X2D184aX2D4ac6X2D9e6aX2Dbd864e34a507genid993 "plasma membrane bounded cell projection organization" "exocytic process" "export from cell" + "defense response to symbiont" "organic substance biosynthetic process" "regulation of leukocyte differentiation" "mononuclear cell differentiation" @@ -728,13 +725,8 @@ _:B29fb0e95X2D184aX2D4ac6X2D9e6aX2Dbd864e34a507genid993 "quality" "morphology" "shape" - "qualitative" - "deviation (from_normal)" - "size" "structure" "circular" - "normal" - "increased size" "elliptic" "physical quality" "physical object quality" @@ -762,14 +754,13 @@ _:B29fb0e95X2D184aX2D4ac6X2D9e6aX2Dbd864e34a507genid993 "subcylindrical" "3-D shape" "tubular" - "increased quality" - "increased object quality" "fiber shaped" "superelliptic" "transversely striated" "nucleated" "disconnected" "polymeric" + "high nuclear/cytoplasmic ratio" "anatomical structure quality" "anatomical histological quality" "neutrophillic" diff --git a/subsets/kidney_upper_slim.json b/subsets/kidney_upper_slim.json index f1316cf80..84c2067cc 100644 --- a/subsets/kidney_upper_slim.json +++ b/subsets/kidney_upper_slim.json @@ -4,9 +4,9 @@ "meta" : { "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2002/07/owl#versionInfo", - "val" : "2024-01-04" + "val" : "2024-02-13" } ], - "version" : "http://purl.obolibrary.org/obo/cl/releases/2024-01-04/subsets/kidney_upper_slim.owl" + "version" : "http://purl.obolibrary.org/obo/cl/releases/2024-02-13/subsets/kidney_upper_slim.owl" }, "nodes" : [ { "id" : "http://purl.obolibrary.org/obo/BFO_0000002", @@ -731,7 +731,7 @@ "xrefs" : [ "CARO:mah" ] }, "comments" : [ "The definition of cell is intended to represent all cells, and thus a cell is defined as a material entity and not an anatomical structure, which implies that it is part of an organism (or the entirety of one)." ], - "subsets" : [ "http://purl.obolibrary.org/obo/ubprop#_upper_level" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/ubprop#_upper_level" ], "xrefs" : [ { "val" : "CALOHA:TS-2035" }, { @@ -772,7 +772,7 @@ "xrefs" : [ "GOC:tfm", "MESH:D013234" ] }, "comments" : [ "This term applies to metazoan. For plant stem cells, consider using PO:0004011 ‘initial cell’ or its parent PO:0004010 ‘meristematic cell’." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "animal stem cell" @@ -797,7 +797,7 @@ "xrefs" : [ "GOC:add", "GOC:dsd", "GOC:tfm", "PMID:19022770", "http://en.wikipedia.org/wiki/Hematopoietic_stem_cell" ] }, "comments" : [ "Markers differ between species, and two sets of markers have been described for mice. HSCs are reportedly CD34-positive, CD45-positive, CD48-negative, CD150-positive, CD133-positive, and CD244-negative." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "blood forming stem cell" @@ -837,7 +837,7 @@ "val" : "A progenitor cell committed to the erythroid lineage.", "xrefs" : [ "GOC:add", "ISBN:0721601464" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003000", "pred" : "hasRelatedSynonym", @@ -911,7 +911,7 @@ "xrefs" : [ "GOC:add", "ISBN:0878932437", "MESH:D023461" ] }, "comments" : [ "This cell type is intended to be compatible with any vertebrate common myeloid progenitor. For mammalian CMP known to be CD34-positive, please use the term 'common myeloid progenitor, CD34-positive' (CL_0001059)." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "common myeloid precursor" @@ -965,7 +965,7 @@ "xrefs" : [ "GOC:add", "GOC:dsd", "GOC:tfm", "MESH:D055015", "PMID:16647566", "http://en.wikipedia.org/wiki/Megakaryocyte-erythroid_progenitor_cell" ] }, "comments" : [ "MEPs are reportedly CD19-negative, CD34-negative, CD45RA-negative, CD110-positive, CD117-positive, and SCA1-negative and reportedly express the transcription factors GATA-1 and NF-E2." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "CFU-EM" @@ -1022,6 +1022,7 @@ "xrefs" : [ "SANBI:mhl" ] }, "comments" : [ "define using PATO mulit-potent or oligopotent?" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "blast cell" @@ -1063,7 +1064,7 @@ "xrefs" : [ "ISBN:0517223651", "MESH:D005347", "http://en.wikipedia.org/wiki/Fibroblast" ] }, "comments" : [ "These cells may be vimentin-positive, fibronectin-positive, fsp1-positive, MMP-1-positive, collagen I-positive, collagen III-positive, and alpha-SMA-negative." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { "val" : "BTO:0000452" }, { @@ -1089,6 +1090,7 @@ "val" : "A cell that has a filiform extrusion of the cell surface.", "xrefs" : [ "GOC:tfm" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "VHOG:0001532" }, { @@ -1104,7 +1106,7 @@ "val" : "A cell that is usually found in a two-dimensional sheet with a free surface. The cell has a cytoskeleton that allows for tight cell to cell contact and for cell polarity where apical part is directed towards the lumen and the basal part to the basal lamina.", "xrefs" : [ "FB:ma", "GOC:tfm", "MESH:D004847" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "epitheliocyte" @@ -1139,6 +1141,7 @@ "val" : "An epithelial cell that has a cilia.", "xrefs" : [ "GOC:tfm" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "FMA:70605" } ] @@ -1151,7 +1154,8 @@ "definition" : { "val" : "An epithelial cell that is part of a duct.", "xrefs" : [ "https://orcid.org/0000-0001-5208-3432" ] - } + }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000071", @@ -1162,7 +1166,7 @@ "val" : "An endothelial cell that lines the vasculature.", "xrefs" : [ "GOC:tfm" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cuboidal endothelial cell of vascular tree" @@ -1185,7 +1189,7 @@ "val" : "A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube.", "xrefs" : [ "GO:0002065", "https://orcid.org/0000-0001-5208-3432" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" @@ -1196,6 +1200,7 @@ "lbl" : "squamous epithelial cell", "type" : "CLASS", "meta" : { + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "CALOHA:TS-1249" } ] @@ -1209,7 +1214,7 @@ "val" : "A cell found predominately in the blood.", "xrefs" : [ "GOC:add", "GOC:tfm" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim" ], "xrefs" : [ { "val" : "FMA:62844" }, { @@ -1226,7 +1231,7 @@ "xrefs" : [ "GOC:tfm", "MESH:D042783", "PMID:21275341", "http://en.wikipedia.org/wiki/Endothelial_cell", "https://sourceforge.net/tracker/?func=detail&atid=440764&aid=3364936&group_id=36855" ] }, "comments" : [ "From FMA: 9.07.2001: Endothelial cell has always been classified as a kind of epithelial cell, specifically a squamous cell but that is not true. First, endothelial cell can either be squamous or cuboidal (e.g. high-endothelial cell) and secondly, it has different embryological derivation (mesodermal) than a true epithelial cell (ectodermal and endodermal). The basis for present classification is the fact that it comprises the outermost layer or lining of anatomical structures (location-based) but a better structural basis for the differentia is the cytoskeleton of the cell. Endothelial cell has vimentin filaments while an epithelial cell has keratin filaments. [Onard]." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "endotheliocyte" @@ -1267,6 +1272,7 @@ "xrefs" : [ "FB:ma", "GOC:dsd", "PMCID:PMC2613570", "PMID:10102814", "PMID:16923606", "PMID:17986482", "PMID:19960544", "http://en.wikipedia.org/wiki/Mesenchymal_stem_cell", "http://www.copewithcytokines.de/cope.cgi?key=mesenchymal%20stem%20cells" ] }, "comments" : [ "Many but not all mesenchymal cells derive from the mesoderm. MSCs are reportedly CD3-negative, CD4-negative, CD5-negative, CD8-negative, CD11a-negative, CD11b-negative, CD14-negative, CD19-negative, CD29-positive, CD31-negative, CD34-negative, CD38-negative, CD40-negative, CD44-positive, CD45-negative, CD49-positive, CD54-positive, CD66b-negative, CD79a-negative, CD80-negative, CD102-positive, CD106-positive, CD117-positive, CD121a-positive, CD121b-positive, CD123-positive, CD124-positive, CD133-negative, CD146-positive, CD166-positive, CD271-positive, B220-negative, Gr1-negative, MHCI-positive, MHCII-negative, SSEA4-negative, sca1-positive, Ter119-negative, and glycophorin A-negative. Cultured MSCs are capable of producing stem cell factor, IL7, IL8, IL11, TGF-beta, cofilin, galectin-1, laminin-receptor 1, cyclophilin A, and MMP-2." ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "bone marrow stromal cells" @@ -1335,6 +1341,7 @@ "val" : "A cell that specializes in controlled release of one or more substances.", "xrefs" : [ "GOC:tfm", "ISBN:0721662544" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "BTO:0003659" }, { @@ -1353,7 +1360,8 @@ "definition" : { "val" : "A cell whose primary function is to shorten.", "xrefs" : [ "FB:ma" ] - } + }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000187", @@ -1364,6 +1372,7 @@ "val" : "A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns.", "xrefs" : [ "MESH:D032342" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "muscle fiber" @@ -1398,7 +1407,7 @@ "val" : "A non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels. They develop from specialized myoblasts (smooth muscle myoblast).", "xrefs" : [ "MESH:D032389", "PMID:9315361", "http://en.wikipedia.org/wiki/Smooth_muscle_cell" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "non-striated muscle cell" @@ -1496,6 +1505,7 @@ "val" : "A cell of the middle germ layer of the embryo.", "xrefs" : [ "MESH:D008648" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "mesoblast" @@ -1533,7 +1543,7 @@ "val" : "A red blood cell. In mammals, mature erythrocytes are biconcave disks containing hemoglobin whose function is to transport oxygen.", "xrefs" : [ "GOC:tfm", "MESH:D004912" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "RBC" @@ -1562,6 +1572,7 @@ "lbl" : "eukaryotic cell", "type" : "CLASS", "meta" : { + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "MESH:D005057" } ] @@ -1653,6 +1664,7 @@ "val" : "A precursor cell destined to differentiate into smooth muscle myocytes.", "xrefs" : [ "GOC:tfm", "MESH:D032390" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "myoblast, smooth muscle", @@ -1675,7 +1687,7 @@ "xrefs" : [ "MESH:D009474", "http://en.wikipedia.org/wiki/Neuron" ] }, "comments" : [ "These cells are also reportedly CD4-negative and CD200-positive. They are also capable of producing CD40L and IFN-gamma." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#general_cell_types_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "nerve cell" @@ -1710,7 +1722,7 @@ "val" : "An immature, nucleated erythrocyte occupying the stage of erythropoeisis that follows formation of erythroid progenitor cells. This cell is CD71-positive, has both a nucleus and a nucleolus, and lacks hematopoeitic lineage markers.", "xrefs" : [ "ISBN:0721601464", "PMID:1638021" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "rubriblast", @@ -1834,7 +1846,7 @@ "xrefs" : [ "GOC:dsd", "GOC:tfm", "ISBN:0721601464" ] }, "comments" : [ "Lineage negative is described here as CD2-negative, CD3-negative, CD4-negative, CD5-negative, CD8a-negative, CD14-negative, CD19-negative, CD20-negative, CD56-negative, Ly6g-negative, and Ter119-negative." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "CFU-Meg", @@ -1894,7 +1906,7 @@ "xrefs" : [ "ISBN:0721601464", "MESH:D008533", "PMID:31043076", "http://en.wikipedia.org/wiki/Megakaryocyte" ] }, "comments" : [ "Megakaryocytes are reportedly CD181-positive and CD182-positive." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "megacaryocyte" @@ -1926,7 +1938,7 @@ "val" : "An immature erythrocyte that changes the protein composition of its plasma membrane by exosome formation and extrusion. The types of protein removed differ between species though removal of the transferrin receptor is apparent in mammals and birds.", "xrefs" : [ "GOC:add", "GOC:tfm", "PMID:15946868", "PMID:2037622" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "BTO:0001173" }, { @@ -1962,6 +1974,7 @@ "val" : "The reproductive cell in multicellular organisms.", "xrefs" : [ "MESH:D005854" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "BTO:0000535" }, { @@ -1981,6 +1994,7 @@ "val" : "A cell whose primary function is to support other cell types.", "xrefs" : [ "FB:ma", "GOC:tfm" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "supportive cell" @@ -2027,6 +2041,7 @@ "xrefs" : [ "GOC:tfm", "http://www.copewithcytokines.de/cope.cgi?key=mesangial%20cells" ] }, "comments" : [ "Do all of these cells really develop from some mesenchymal stem cell?" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "kidney mesangial cell" @@ -2046,6 +2061,7 @@ "lbl" : "fenestrated cell", "type" : "CLASS", "meta" : { + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "window cell" @@ -2061,7 +2077,7 @@ "xrefs" : [ "GOC:dsd", "GOC:tfm", "ISBN:0721662544", "MESH:D020286", "PMID:16807374", "PMID:17986482", "PMID:20024907" ] }, "comments" : [ "Pericytes are CD10-positive, CD13-positive, CD31-negative, CD45-negative, CD106-positive, CD117-negative, CD140-positive, CD144-negative, CD146-positive, CD271-positive, CD325-positive, NG2-positive, RGS5-positive, SMA-positive, and desmin-positive. A subpopulation is CD248-positive. They are also capable of producing angiopoietin 1, CXCL12, TGF-beta, and VEGF-A." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "ARC", @@ -2100,7 +2116,8 @@ "definition" : { "val" : "A non-terminally differentiated cell that is capable of developing into a muscle cell.", "xrefs" : [ "GOC:add" ] - } + }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0000723", @@ -2126,6 +2143,7 @@ "val" : "A cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage.", "xrefs" : [ "GOC:add" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "BTO:0001441" }, { @@ -2144,7 +2162,7 @@ "xrefs" : [ "GOC:add", "GOC:tfm" ] }, "comments" : [ "Note that in FMA erythropoietic cells are types of nucleated erythrocytes and thus don't include erythrocytes." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "erythropoietic cell" @@ -2170,7 +2188,7 @@ "val" : "A nucleated precursor of an erythrocyte that lacks hematopoietic lineage markers.", "xrefs" : [ "GOC:add", "ISBN:0721601464", "PMID:18174176" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "normoblast" @@ -2195,7 +2213,7 @@ "xrefs" : [ "GOC:add", "GOC:tfm", "PMID:19022770" ] }, "comments" : [ "Markers differ between mouse and human." ], - "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "MPP" @@ -2223,7 +2241,7 @@ "xrefs" : [ "GOC:add", "GOC:tfm", "PMID:19022770" ] }, "comments" : [ "Note that this is a class of cell types, not an identified single cell type." ], - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "myeloid progenitor cell" @@ -2249,6 +2267,7 @@ "val" : "A cell of a hematopoietic lineage.", "xrefs" : [ "GOC:add", "GO_REF:0000031" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "haematopoietic cell" @@ -2360,6 +2379,7 @@ "xrefs" : [ "GOC:dsd", "GOC:tfm", "PMID:12768659" ] }, "comments" : [ "These cells are reportedly CD31-positive, CD34-positive, CD144-positive, TAL1-positive." ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "vascular endothelial cell" @@ -2423,7 +2443,7 @@ "val" : "An endothelial cell found in the glomerulus of the kidney. This cell is flattened, highly fenestrated, and plays a vital role in the formation of glomerular ultrafiltrate.", "xrefs" : [ "GOC:tfm", "PMID:15840009" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#kidney_upper_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#kidney_upper_slim" ], "xrefs" : [ { "val" : "BTO:0004632" }, { @@ -2486,7 +2506,7 @@ "val" : "An epithelial cell of the proximal tubule of the kidney.", "xrefs" : [ "GOC:tfm", "ISBN:1-4160-2328-3" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#kidney_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#kidney_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "kidney proximal tubule epithelial cell" @@ -2510,6 +2530,7 @@ "val" : "A cell that is part of the nervous system.", "xrefs" : [ "GOC:tfm", "ISBN:0618947256" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "CALOHA:TS-2040" }, { @@ -2532,6 +2553,7 @@ "val" : "A cell of the supporting or framework tissue of the body, arising chiefly from the embryonic mesoderm and including adipose tissue, cartilage, and bone.", "xrefs" : [ "GOC:tfm", "ISBN:0618947256" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "CALOHA:TS-2096" }, { @@ -2611,6 +2633,7 @@ "val" : "An epithelial cell of the kidney.", "xrefs" : [ "GOC:tfm", "KUPO:SJ" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "KUPO:0001019" } ], @@ -2677,7 +2700,8 @@ "definition" : { "val" : "A cuboidal epithelial cell of the kidney which regulates sodium and potassium balance. The activity of sodium and potassium channels on the apical membrane of the cell is regulated by aldosterone and vasopressin. In mammals this cell type is located in the renal collecting duct system.", "xrefs" : [ "CL:CVS" ] - } + }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0007004", @@ -2714,7 +2738,8 @@ "definition" : { "val" : "Any hematopoietic cell that is a precursor of some other hematopoietic cell type.", "xrefs" : [ "GOC:dos" ] - } + }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0008007", @@ -2737,7 +2762,7 @@ "definition" : { "val" : "A non-polarised cell precursor cell that is part of some mesenchyme, is associated with the cell matrix but is not connected to other cells and is capable of migration." }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "mesenchyme cell" @@ -2756,7 +2781,7 @@ "val" : "Mural cells are pericytes and the vascular smooth muscle cells (vSMCs) of the microcirculation.", "xrefs" : [ "Wiki:Mural_cell&oldid=930603194" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#added_for_HCA", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#added_for_HCA", "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" @@ -2792,7 +2817,8 @@ "definition" : { "val" : "A cell of the neural crest. Neural crest cells are multipotent. Premigratory neural crest cells are found at the neural plate boarder, some of which will undergo ectomesynchymal transition and delamination to form migratory neural crest cells.", "xrefs" : [ "https://orcid.org/0000-0001-5208-3432", "https://orcid.org/0000-0002-9900-7880" ] - } + }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0011026", @@ -2803,6 +2829,7 @@ "val" : "A precursor cell that has a tendency to differentiate into a specific type of cell. They are descendants of stem cells, only they are more constrained in their differentiation potential or capacity for self-renewal, and are often more limited in both senses.", "xrefs" : [ "ISBN:978-1-62808-994-3", "https://doi.org/10.1016/B978-0-12-409503-8.00002-0" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "basicPropertyValues" : [ { "pred" : "http://purl.org/dc/terms/contributor", "val" : "https://orcid.org/0000-0001-5208-3432" @@ -2817,7 +2844,8 @@ "val" : "A cell that, by division or terminal differentiation, can give rise to other cell types.", "xrefs" : [ "GOC:dos" ] }, - "comments" : [ "Work is needed on GO 'cell differentiation' before it is clear whether the equivalent class definition 'native cell' that capable_of some 'cell differentiation' works. Also, may want to consider merging this with non-terminally differentiated cell." ] + "comments" : [ "Work is needed on GO 'cell differentiation' before it is clear whether the equivalent class definition 'native cell' that capable_of some 'cell differentiation' works. Also, may want to consider merging this with non-terminally differentiated cell." ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ] } }, { "id" : "http://purl.obolibrary.org/obo/CL_0017502", @@ -2874,23 +2902,6 @@ "val" : "2009-12-28T04:25:23Z" } ] } - }, { - "id" : "http://purl.obolibrary.org/obo/CL_0017505", - "lbl" : "increased nucleus size", - "type" : "CLASS", - "meta" : { - "definition" : { - "val" : "A nucleus size quality which is relatively high compared to the amount of cytoplasm present in the same cell.", - "xrefs" : [ "GOC:tfm" ] - }, - "basicPropertyValues" : [ { - "pred" : "http://purl.org/dc/terms/contributor", - "val" : "https://orcid.org/0000-0003-1980-3228" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", - "val" : "2009-12-23T10:53:24Z" - } ] - } }, { "id" : "http://purl.obolibrary.org/obo/CL_1000449", "lbl" : "epithelial cell of nephron", @@ -2900,6 +2911,7 @@ "val" : "An epithelial cell that is part of the nephron.", "xrefs" : [ "GOC:tfm" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "FMA:70965" } ] @@ -2913,7 +2925,7 @@ "val" : "An epithelial cell that is part of the glomerular capsule.", "xrefs" : [ "GOC:tfm" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#kidney_upper_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#kidney_upper_slim" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "Bowmans capsule epithelial cell" @@ -2937,7 +2949,7 @@ "val" : "An epithelial cell that is part of the collecting duct of renal tubule.", "xrefs" : [ "GOC:tfm" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#kidney_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#kidney_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "epithelial cell of renal collecting tubule", @@ -2963,6 +2975,7 @@ "xrefs" : [ "GOC:tfm" ] }, "comments" : [ "This needs to be further defined as a juxtamedullary nephron. Will request the juxtamedullary nephron tubule class from UBERON." ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "kidney tubule epithelial cell" @@ -2981,6 +2994,7 @@ "definition" : { "val" : "A cell that is part of a kidney." }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "KUPO:0001010" } ] @@ -2993,7 +3007,7 @@ "definition" : { "val" : "A cell that is part of kidney interstitium." }, - "subsets" : [ "http://purl.obolibrary.org/obo/cl#kidney_upper_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#kidney_upper_slim" ], "xrefs" : [ { "val" : "KUPO:0001013" } ] @@ -3041,6 +3055,7 @@ "lbl" : "kidney glomerular epithelial cell", "type" : "CLASS", "meta" : { + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "KUPO:0001023" } ] @@ -3083,6 +3098,7 @@ "lbl" : "kidney cortex tubule cell", "type" : "CLASS", "meta" : { + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "KUPO:0001024" } ] @@ -3107,7 +3123,7 @@ "lbl" : "kidney interstitial fibroblast", "type" : "CLASS", "meta" : { - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { "val" : "KUPO:0001102" } ], @@ -3130,7 +3146,7 @@ "lbl" : "kidney connecting tubule epithelial cell", "type" : "CLASS", "meta" : { - "subsets" : [ "http://purl.obolibrary.org/obo/cl#kidney_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#kidney_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { "val" : "KUPO:0001058" } ], @@ -3144,7 +3160,7 @@ "lbl" : "kidney distal convoluted tubule epithelial cell", "type" : "CLASS", "meta" : { - "subsets" : [ "http://purl.obolibrary.org/obo/cl#kidney_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#kidney_upper_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { "val" : "KUPO:0001056" } ], @@ -3177,7 +3193,7 @@ "lbl" : "kidney capillary endothelial cell", "type" : "CLASS", "meta" : { - "subsets" : [ "http://purl.obolibrary.org/obo/cl#kidney_upper_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#kidney_upper_slim" ], "xrefs" : [ { "val" : "KUPO:0001030" } ] @@ -3197,6 +3213,7 @@ "lbl" : "kidney loop of Henle epithelial cell", "type" : "CLASS", "meta" : { + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "KUPO:0001047" } ] @@ -3206,7 +3223,7 @@ "lbl" : "kidney loop of Henle ascending limb epithelial cell", "type" : "CLASS", "meta" : { - "subsets" : [ "http://purl.obolibrary.org/obo/cl#kidney_upper_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/cl#kidney_upper_slim" ], "xrefs" : [ { "val" : "KUPO:0001048" } ] @@ -3229,6 +3246,7 @@ "definition" : { "val" : "A cell that is part of a collecting duct of renal tubule." }, + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset" ], "xrefs" : [ { "val" : "KUPO:0001012" }, { @@ -3243,7 +3261,7 @@ "definition" : { "val" : "A pericyte cell located in the kidney interstitium." }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], + "subsets" : [ "http://purl.obolibrary.org/obo/cl#cellxgene_subset", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "xrefs" : [ { "val" : "KUPO:0001104" } ], @@ -4099,7 +4117,7 @@ "type" : "CLASS", "meta" : { "definition" : { - "val" : "A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex).", + "val" : "A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex).", "xrefs" : [ "GOC:pdt" ] }, "comments" : [ "Note that, in addition to forming the root of the cellular component ontology, this term is recommended for the annotation of gene products whose cellular component is unknown. When this term is used for annotation, it indicates that no information was available about the cellular component of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this." ], @@ -4139,7 +4157,7 @@ "xrefs" : [ "GOC:go_curators" ] }, "comments" : [ "Note that this term is intended to annotate gene products that are not attached to the cell surface. For gene products from multicellular organisms which are secreted from a cell but retained within the organism (i.e. released into the interstitial fluid or blood), consider the cellular component term 'extracellular space ; GO:0005615'." ], - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_yeast", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "extracellular" @@ -4257,7 +4275,7 @@ "xrefs" : [ "ISBN:0198547684" ] }, "comments" : [ "Note that for multicellular organisms, the extracellular space refers to everything outside a cell, but still within the organism (excluding the extracellular matrix). Gene products from a multi-cellular organism that are secreted from a cell into the interstitial fluid or blood can therefore be annotated to this term." ], - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "intercellular space" @@ -4347,7 +4365,7 @@ "xrefs" : [ "ISBN:0198547684" ] }, "comments" : [ "Chromosomes include parts that are not part of the chromatin. Examples include the kinetochore." ], - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_yeast", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "interphase chromosome" @@ -4395,7 +4413,7 @@ "val" : "The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.", "xrefs" : [ "ISBN:0198547684" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_yeast", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "xrefs" : [ { "val" : "Wikipedia:Cytoplasm" } ], @@ -4495,7 +4513,7 @@ "val" : "An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins.", "xrefs" : [ "ISBN:0198506732" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_yeast", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "free ribosome", @@ -4530,7 +4548,7 @@ "val" : "A cellular structure that forms the internal framework of eukaryotic and prokaryotic cells. The cytoskeleton includes intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.", "xrefs" : [ "GOC:mah", "PMID:16959967", "PMID:27419875" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_yeast", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "xrefs" : [ { "val" : "Wikipedia:Cytoskeleton" } ], @@ -4579,7 +4597,7 @@ "val" : "The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.", "xrefs" : [ "ISBN:0716731363" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_yeast", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "juxtamembrane" @@ -4764,7 +4782,7 @@ "val" : "The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.", "xrefs" : [ "GOC:go_curators" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "protein anabolism" @@ -4903,7 +4921,7 @@ "xrefs" : [ "GOC:dos", "GOC:dph", "GOC:jl", "GOC:mah" ] }, "comments" : [ "Note that this term should not be used for direct annotation. It should be possible to make a more specific annotation to one of the children of this term, for e.g. to transmembrane transport, to microtubule-based transport or to vesicle-mediated transport." ], - "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "single-organism transport" @@ -5148,7 +5166,7 @@ "val" : "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures.", "xrefs" : [ "GOC:dph", "GOC:jl", "GOC:mah" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_yeast", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cytoskeleton organisation" @@ -5742,7 +5760,7 @@ "val" : "Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538).", "xrefs" : [ "GOC:mah", "GOC:mtg_apoptosis", "PMID:25236395" ] }, - "comments" : [ "This term should not be used for direct annotation, it is currently kept in GO as a placeholder for describing cell death phenotypes in uPHENO. When information is provided on a programmed cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'). Unintentional cell death, i.e. cell death caused by injury, ageing, or cell phenotypes observed as a result of a pathological mutation in an essential gene should NOT be annotated using GO terms." ], + "comments" : [ "This term should not be used for direct annotation, it is currently kept in GO as a placeholder for describing cell death phenotypes in uPHENO. When information is provided on a programmed cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'). Unintentional cell death, i.e. cell death caused by injury, ageing, or cell phenotypes observed as a result of a pathological mutation in an essential gene should NOT be annotated using GO terms." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", @@ -6142,7 +6160,7 @@ "xrefs" : [ "GOC:lr", "GOC:mtg_apoptosis" ] }, "comments" : [ "Note that this term should be used to annotate gene products in the organism undergoing the programmed cell death. To annotate genes in another organism whose products modulate programmed cell death in a host organism, consider the term 'modulation by symbiont of host programmed cell death ; GO:0052040'. Also, note that 'programmed cell death ; GO:0012501' should be used to refer to instances of caspase-independent cell death mechanisms, in the absence of further indications on the process taking place. At present, caspase-independent cell death is not yet represented in GO due to the lack of consensus and in-depth research on the topic. 'programmed cell death ; GO:0012501' may also be used to annotate gene products in taxa where apoptosis as defined in GO:0006915 does not occur, such as plants. You may also consider these specific children: GO:0097468 'programmed cell death in response to reactive oxygen species' (with descendants GO:0010421 'hydrogen peroxide-mediated programmed cell death' and GO:0010343 'singlet oxygen-mediated programmed cell death'), and GO:0009626 'plant-type hypersensitive response' and its children." ], - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "regulated cell death" @@ -6760,7 +6778,7 @@ "xrefs" : [ "GOC:mtg_signal", "GOC:mtg_signaling_feb11", "GOC:signaling" ] }, "comments" : [ "Note that a signal is any variable property or parameter that serves to convey information, and may be a physical entity such as a gene product or small molecule, a photon, or a change in state such as movement or voltage change." ], - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pombe", "http://purl.obolibrary.org/obo/go#goslim_yeast", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pombe", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "biological signaling" @@ -6826,7 +6844,7 @@ "val" : "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon.", "xrefs" : [ "GOC:jl", "GOC:mah", "http://www.cogsci.princeton.edu/~wn/" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cell projection organisation" @@ -7144,7 +7162,7 @@ "val" : "A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues.", "xrefs" : [ "GOC:BHF", "GOC:mah", "GOC:rph", "NIF_Subcellular:nlx_subcell_20090513", "PMID:21123617", "PMID:28089324" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "proteinaceous extracellular matrix" @@ -8025,7 +8043,7 @@ "val" : "A prolongation or process extending from a cell, e.g. a flagellum or axon.", "xrefs" : [ "GOC:jl", "http://www.cogsci.princeton.edu/~wn/" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "cell process" @@ -8082,7 +8100,7 @@ "val" : "The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.", "xrefs" : [ "GOC:mah" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_pir" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_pir" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "biopolymer metabolic process", @@ -8098,6 +8116,9 @@ "val" : "multicellular organismal macromolecule metabolic process" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/26424" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0034960" }, { @@ -8120,7 +8141,7 @@ "val" : "Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane.", "xrefs" : [ "GOC:go_curators" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "xrefs" : [ { "val" : "NIF_Subcellular:sao1539965131" }, { @@ -8420,12 +8441,15 @@ "val" : "The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.", "xrefs" : [ "GOC:go_curators", "http://www.metacyc.org" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_pir" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_pir" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "primary metabolism" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/26424" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] @@ -8847,12 +8871,15 @@ "val" : "The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.", "xrefs" : [ "GO_REF:0000021" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_plant" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_plant" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "development of an anatomical structure" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/26424" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] @@ -8880,7 +8907,7 @@ "val" : "Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another.", "xrefs" : [ "GOC:dgh", "GOC:dph", "GOC:isa_complete", "GOC:mlg" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cell locomotion" @@ -9082,7 +9109,7 @@ "xrefs" : [ "GOC:ai", "GOC:bf" ] }, "comments" : [ "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ], - "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_manually_annotate", "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_manually_annotate", "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "physiological response to stimulus" @@ -9675,7 +9702,7 @@ "val" : "The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex.", "xrefs" : [ "GOC:jl" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_pombe", "http://purl.obolibrary.org/obo/go#prokaryote_subset" ], + "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_pombe", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cellular protein complex assembly" @@ -9982,6 +10009,7 @@ "val" : "The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon.", "xrefs" : [ "GOC:mah" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "organic molecular entity metabolic process" @@ -9993,6 +10021,9 @@ "val" : "organic substance metabolism" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/26424" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "mah" }, { @@ -10084,7 +10115,7 @@ "type" : "CLASS", "meta" : { "definition" : { - "val" : "The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures.", + "val" : "The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures.", "xrefs" : [ "GOC:pdt" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon" ], @@ -10717,6 +10748,9 @@ "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/24200" + }, { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/geneontology/go-ontology/issues/26424" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "kmv" @@ -12438,47 +12472,6 @@ "val" : "quality" } ] } - }, { - "id" : "http://purl.obolibrary.org/obo/PATO_0000068", - "lbl" : "qualitative", - "type" : "CLASS", - "meta" : { - "comments" : [ "TODO: define this or obsolete it and move children somewhere else." ], - "basicPropertyValues" : [ { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", - "val" : "quality" - } ] - } - }, { - "id" : "http://purl.obolibrary.org/obo/PATO_0000069", - "lbl" : "deviation (from_normal)", - "type" : "CLASS", - "meta" : { - "definition" : { - "val" : "A quality inhering in a bearer by virtue of the whether the bearer differs from normal or average.", - "xrefs" : [ "PATOC:GVG" ] - }, - "subsets" : [ "http://purl.obolibrary.org/obo/pato#attribute_slim" ], - "basicPropertyValues" : [ { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", - "val" : "quality" - } ] - } - }, { - "id" : "http://purl.obolibrary.org/obo/PATO_0000117", - "lbl" : "size", - "type" : "CLASS", - "meta" : { - "definition" : { - "val" : "A morphology quality inhering in a bearer by virtue of the bearer's physical magnitude.", - "xrefs" : [ "WordNet:WordNet" ] - }, - "subsets" : [ "http://purl.obolibrary.org/obo/pato#attribute_slim", "http://purl.obolibrary.org/obo/pato#scalar_slim" ], - "basicPropertyValues" : [ { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", - "val" : "quality" - } ] - } }, { "id" : "http://purl.obolibrary.org/obo/PATO_0000141", "lbl" : "structure", @@ -12552,65 +12545,6 @@ "val" : "quality" } ] } - }, { - "id" : "http://purl.obolibrary.org/obo/PATO_0000461", - "lbl" : "normal", - "type" : "CLASS", - "meta" : { - "definition" : { - "val" : "A quality inhering in a bearer by virtue of the bearer's exhibiting no deviation from normal or average.", - "xrefs" : [ "PATOC:GVG" ] - }, - "subsets" : [ "http://purl.obolibrary.org/obo/pato#abnormal_slim", "http://purl.obolibrary.org/obo/pato#mpath_slim", "http://purl.obolibrary.org/obo/pato#value_slim" ], - "synonyms" : [ { - "pred" : "hasRelatedSynonym", - "val" : "average" - } ], - "basicPropertyValues" : [ { - "pred" : "http://purl.obolibrary.org/obo/RO_0002604", - "val" : "http://purl.obolibrary.org/obo/PATO_0000460" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", - "val" : "quality" - } ] - } - }, { - "id" : "http://purl.obolibrary.org/obo/PATO_0000586", - "lbl" : "increased size", - "type" : "CLASS", - "meta" : { - "definition" : { - "val" : "A size quality which is relatively high.", - "xrefs" : [ "PATOC:GVG" ] - }, - "subsets" : [ "http://purl.obolibrary.org/obo/pato#value_slim" ], - "synonyms" : [ { - "pred" : "hasRelatedSynonym", - "val" : "big" - }, { - "pred" : "hasRelatedSynonym", - "val" : "enlarged" - }, { - "pred" : "hasRelatedSynonym", - "val" : "expanded" - }, { - "pred" : "hasRelatedSynonym", - "val" : "great" - }, { - "pred" : "hasRelatedSynonym", - "val" : "large" - } ], - "basicPropertyValues" : [ { - "pred" : "http://purl.obolibrary.org/obo/RO_0002604", - "val" : "http://purl.obolibrary.org/obo/PATO_0000587" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", - "val" : "PATO:0001202" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", - "val" : "quality" - } ] - } }, { "id" : "http://purl.obolibrary.org/obo/PATO_0000947", "lbl" : "elliptic", @@ -13292,52 +13226,6 @@ "val" : "quality" } ] } - }, { - "id" : "http://purl.obolibrary.org/obo/PATO_0002300", - "lbl" : "increased quality", - "type" : "CLASS", - "meta" : { - "definition" : { - "val" : "A quality that has a value that is increased compared to normal or average.", - "xrefs" : [ "PATOC:GVG" ] - }, - "basicPropertyValues" : [ { - "pred" : "http://purl.obolibrary.org/obo/RO_0002604", - "val" : "http://purl.obolibrary.org/obo/PATO_0002301" - }, { - "pred" : "http://purl.org/dc/terms/contributor", - "val" : "https://orcid.org/0000-0002-2061-091X" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", - "val" : "2011-06-16T06:39:43Z" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", - "val" : "quality" - } ] - } - }, { - "id" : "http://purl.obolibrary.org/obo/PATO_0002305", - "lbl" : "increased object quality", - "type" : "CLASS", - "meta" : { - "definition" : { - "val" : "A quality of an object that has a value that is increased compared to normal or average.", - "xrefs" : [ "PATOC:GVG" ] - }, - "basicPropertyValues" : [ { - "pred" : "http://purl.obolibrary.org/obo/RO_0002604", - "val" : "http://purl.obolibrary.org/obo/PATO_0002303" - }, { - "pred" : "http://purl.org/dc/terms/contributor", - "val" : "https://orcid.org/0000-0002-2061-091X" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", - "val" : "2011-06-16T06:54:01Z" - }, { - "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", - "val" : "quality" - } ] - } }, { "id" : "http://purl.obolibrary.org/obo/PATO_0002309", "lbl" : "fiber shaped", @@ -13503,6 +13391,28 @@ "val" : "quality" } ] } + }, { + "id" : "http://purl.obolibrary.org/obo/PATO_0040072", + "lbl" : "high nuclear/cytoplasmic ratio", + "type" : "CLASS", + "meta" : { + "definition" : { + "val" : "A quality inhering in a cell by virtue of the cell having a high nuclear/cytoplasmic ratio.", + "xrefs" : [ "Wikipedia:NC_ratio&oldid=931936284", "http://lymerick.net/blood-cells.pdf" ] + }, + "comments" : [ "A high nuclear/cytolasmic ratio is 70% or higher." ], + "synonyms" : [ { + "pred" : "hasExactSynonym", + "val" : "high N:C ratio" + } ], + "basicPropertyValues" : [ { + "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", + "val" : "http://orcid.org/0000-0001-5208-3432" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "quality" + } ] + } }, { "id" : "http://purl.obolibrary.org/obo/PATO_0070044", "lbl" : "anatomical structure quality", @@ -16341,6 +16251,9 @@ "val" : "inverse of develops from" }, "subsets" : [ "http://purl.obolibrary.org/obo/RO_0002259" ], + "xrefs" : [ { + "val" : "RO:0002203" + } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000114", "val" : "http://purl.obolibrary.org/obo/IAO_0000125" @@ -16353,6 +16266,12 @@ }, { "pred" : "http://purl.obolibrary.org/obo/IAO_0000117", "val" : "https://orcid.org/0000-0003-1980-3228" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", + "val" : "uberon" + }, { + "pred" : "http://www.geneontology.org/formats/oboInOwl#shorthand", + "val" : "develops_into" } ] } }, { @@ -21451,7 +21370,7 @@ "pred" : "hasRelatedSynonym", "val" : "glomerular tuft" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "glomerulus renis", "xrefs" : [ "Wikipedia:Glomerulus" ] @@ -21752,7 +21671,7 @@ "val" : "renal tubules", "xrefs" : [ "VHOG:0000500" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "tubuli mesonephrici", "xrefs" : [ "Wikipedia:Mesonephric_tubules" ] @@ -21799,12 +21718,12 @@ "val" : "diverticulum", "xrefs" : [ "BTO:0001646" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "diverticulum metanephricum", "xrefs" : [ "Wikipedia:Ureteric_bud" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "gemma ureterica", "xrefs" : [ "Wikipedia:Ureteric_bud" ] @@ -22056,7 +21975,7 @@ "val" : "zygote", "xrefs" : [ "VHOG:0000745" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "zygotum", "xrefs" : [ "Wikipedia:Zygote" ] @@ -22559,7 +22478,7 @@ "val" : "fetal UGS", "xrefs" : [ "PMID:18977204" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "sinus urogenitalis" } ], @@ -22610,7 +22529,7 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#efo_slim", "http://purl.obolibrary.org/obo/uberon/core#major_organ", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "regio oralis", "xrefs" : [ "BTO:0004698", "FMA:49184", "FMA:TA" ] @@ -22618,7 +22537,7 @@ "pred" : "hasNarrowSynonym", "val" : "adult mouth" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "cavital oralis", "xrefs" : [ "Wikipedia:Mouth" ] @@ -22975,6 +22894,8 @@ "xrefs" : [ "Wikipedia:Parenchyma" ] }, "xrefs" : [ { + "val" : "BTO:0000999" + }, { "val" : "BTO:0001539" }, { "val" : "EHDAA:3015" @@ -23043,12 +22964,12 @@ "val" : "medulla of kidney", "xrefs" : [ "OBOL:automatic" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "medulla renalis", "xrefs" : [ "FMA:74268", "FMA:TA" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "pyramides renales", "xrefs" : [ "FMA:74268", "FMA:TA" ] @@ -23896,8 +23817,6 @@ "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#common_anatomy", "http://purl.obolibrary.org/obo/uberon/core#upper_level" ], "xrefs" : [ { "val" : "FBbt:00007277" - }, { - "val" : "IDOMAL:0002461" }, { "val" : "VHOG:0001737" } ], @@ -25355,7 +25274,7 @@ "val" : "Anatomical system that has as its parts the organs concerned with reproduction.", "xrefs" : [ "Wikipedia:Reproductive_system" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#efo_slim", "http://purl.obolibrary.org/obo/uberon/core#functional_classification", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], + "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#efo_slim", "http://purl.obolibrary.org/obo/uberon/core#functional_classification", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "genital system" @@ -25386,7 +25305,7 @@ "pred" : "hasRelatedSynonym", "val" : "reproductive tract" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "systemata genitalia", "xrefs" : [ "Wikipedia:Reproductive_system" ] @@ -25421,6 +25340,8 @@ "val" : "HAO:0000895" }, { "val" : "MA:0000326" + }, { + "val" : "MESH:D005835" }, { "val" : "MIAA:0000305" }, { @@ -25445,6 +25366,9 @@ "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000116", "val" : "consider splitting genitalia from reproductive system" + }, { + "pred" : "http://purl.obolibrary.org/obo/RO_0002175", + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" }, { "pred" : "http://purl.obolibrary.org/obo/UBPROP_0000001", "val" : "Anatomical system which consists of organs and tissues associated with sexual reproduction of the organism.[AAO]" @@ -25760,7 +25684,7 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "systema cardiovasculare", "xrefs" : [ "Wikipedia:Circulatory_system" ] @@ -25769,6 +25693,8 @@ "val" : "AAO:0000959" }, { "val" : "CALOHA:TS-2103" + }, { + "val" : "MESH:D002319" }, { "val" : "VHOG:0001248" }, { @@ -25826,7 +25752,7 @@ "pred" : "hasExactSynonym", "val" : "musculature" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "musculi", "xrefs" : [ "FMA:32558", "FMA:TA" ] @@ -25900,7 +25826,7 @@ "val" : "The nervous system is an organ system containing predominantly neuron and glial cells. In bilaterally symmetrical organism, it is arranged in a network of tree-like structures connected to a central body. The main functions of the nervous system are to regulate and control body functions, and to receive sensory input, process this information, and generate behavior [CUMBO].", "xrefs" : [ "BIRNLEX:844", "ISBN:0-14-051288-8", "ISBN:3110148986", "NLM:nervous+system", "WB:rynl", "Wikipedia:Nervous_system", "ZFIN:curator" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#cumbo", "http://purl.obolibrary.org/obo/uberon/core#efo_slim", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], + "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#cumbo", "http://purl.obolibrary.org/obo/uberon/core#efo_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "neurological system", @@ -25910,7 +25836,7 @@ "val" : "nerve net", "xrefs" : [ "Wikipedia:Nerve_net" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "systema nervosum", "xrefs" : [ "Wikipedia:Nervous_system" ] @@ -25973,6 +25899,9 @@ "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_6040" + }, { + "pred" : "http://purl.obolibrary.org/obo/RO_0002175", + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" }, { "pred" : "http://purl.obolibrary.org/obo/UBPROP_0000001", "val" : "A regulatory system of the body that consists of neurons and neuroglial cells. The nervous system is divided into two parts, the central nervous system (CNS) and the peripheral nervous system (PNS). (Source: BioGlossary, www.Biology-Text.com)[TAO]" @@ -26008,13 +25937,13 @@ "val" : "The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the neural tube derivatives: the brain and spinal cord. In invertebrates it includes central ganglia plus nerve cord.", "xrefs" : [ "GO:0021551", "http://www.frontiersinzoology.com/content/7/1/29", "https://sourceforge.net/p/geneontology/ontology-requests/11422/" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#cumbo", "http://purl.obolibrary.org/obo/uberon/core#efo_slim", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], + "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#cumbo", "http://purl.obolibrary.org/obo/uberon/core#efo_slim", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], "synonyms" : [ { "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003000", "pred" : "hasExactSynonym", "val" : "CNS" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "systema nervosum centrale", "xrefs" : [ "FMA:55675", "FMA:TA" ] @@ -26085,6 +26014,9 @@ "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_147099" + }, { + "pred" : "http://purl.obolibrary.org/obo/RO_0002175", + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" }, { "pred" : "http://purl.obolibrary.org/obo/UBPROP_0000001", "val" : "Part of the nervous system which includes the brain and spinal cord.[AAO]" @@ -26113,12 +26045,12 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#developmental_classification", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "praeenteron", "xrefs" : [ "Wikipedia:Foregut" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "proenteron", "xrefs" : [ "Wikipedia:Foregut" ] @@ -26184,7 +26116,7 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#developmental_classification", "http://purl.obolibrary.org/obo/uberon/core#efo_slim", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "mesenteron", "xrefs" : [ "Wikipedia:Midgut" ] @@ -26253,7 +26185,7 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#developmental_classification", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "metenteron", "xrefs" : [ "Wikipedia:Hindgut" ] @@ -26385,7 +26317,7 @@ "pred" : "hasRelatedSynonym", "val" : "presumptive central nervous system" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "tubus neuralis", "xrefs" : [ "Wikipedia:Neural_tube" ] @@ -26546,7 +26478,7 @@ "pred" : "hasRelatedSynonym", "val" : "postcava" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "vena cava inferior", "xrefs" : [ "BTO:0002682", "Wikipedia:Inferior_vena_cava" ] @@ -26670,7 +26602,7 @@ "val" : "vein of kidney", "xrefs" : [ "OBOL:automatic" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "venae renales", "xrefs" : [ "Wikipedia:Renal_vein" ] @@ -26743,7 +26675,7 @@ "pred" : "hasExactSynonym", "val" : "pelvis of ureter" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "p. renallis", "xrefs" : [ "Wikipedia:Renal_pelvis" ] @@ -26797,7 +26729,7 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "cortex renalis", "xrefs" : [ "FMA:15581", "FMA:TA" ] @@ -26880,11 +26812,11 @@ "val" : "Malpighian corpuscle", "xrefs" : [ "ZFA:0005281" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "corpusculum renale" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "corpusculum renis", "xrefs" : [ "Wikipedia:Renal_corpuscle" ] @@ -26965,7 +26897,7 @@ "val" : "Bowmans capsule", "xrefs" : [ "KUPO:0001001" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "capsula glomerularis" }, { @@ -26994,7 +26926,7 @@ "val" : "Muellerian capsule", "xrefs" : [ "BTO:0002297" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "capsula glomeruli" }, { @@ -27142,7 +27074,7 @@ "val" : "renal collecting tubule", "xrefs" : [ "FMA:15628" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "tubulus renalis arcuatus", "xrefs" : [ "Wikipedia:Connecting_tubule" ] @@ -27300,7 +27232,7 @@ "val" : "bladder", "xrefs" : [ "EHDAA2:0000174" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "vesica urinaria", "xrefs" : [ "Wikipedia:Urinary_bladder" ] @@ -27448,12 +27380,12 @@ "val" : "mature nephron", "xrefs" : [ "EMAPA:28491" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "nephroneum", "xrefs" : [ "Wikipedia:Nephron" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "tubulus renalis", "xrefs" : [ "Wikipedia:Nephron" ] @@ -27543,12 +27475,12 @@ "val" : "renal proximal convoluted tubule", "xrefs" : [ "http://orcid.org/0000-0002-6601-2165" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "tubulus contortus proximalis", "xrefs" : [ "Wikipedia:Proximal_convoluted_tubule" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "tubulus convolutus proximalis" } ], @@ -27603,7 +27535,7 @@ "pred" : "hasExactSynonym", "val" : "Henle's loop" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "ansa nephroni", "xrefs" : [ "Wikipedia:Loop_of_Henle" ] @@ -27795,12 +27727,12 @@ "pred" : "hasRelatedSynonym", "val" : "second convoluted tubule" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "tubulus contortus distalis", "xrefs" : [ "Wikipedia:Distal_convoluted_tubule" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "tubulus convolutus distalis" } ], @@ -27862,12 +27794,12 @@ "val" : "renal outer medulla", "xrefs" : [ "BTO:0001746" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "zona externa (medullaris renalis)", "xrefs" : [ "FMA:17733", "FMA:TA" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "zona externa medullae renalis", "xrefs" : [ "FMA:17733", "FMA:TA" ] @@ -28126,6 +28058,8 @@ "val" : "FMA:45615" }, { "val" : "MA:0000917" + }, { + "val" : "MESH:D041981" }, { "val" : "NCIT:C34082" }, { @@ -28181,7 +28115,7 @@ "val" : "Subdivision of urinary system which consists of the urinary bladder and the urethra.", "xrefs" : [ "FMA:45659" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim" ], + "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim" ], "xrefs" : [ { "val" : "FMA:45659" }, { @@ -28192,6 +28126,9 @@ "val" : "galen:LowerUrinaryTract" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/RO_0002175", + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "uberon" } ] @@ -28376,7 +28313,7 @@ "val" : "vascular element", "xrefs" : [ "EMAPA:th" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "vena", "xrefs" : [ "Wikipedia:Vein" ] @@ -28564,7 +28501,7 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "venula", "xrefs" : [ "Wikipedia:Venule" ] @@ -28619,7 +28556,7 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "arteriola", "xrefs" : [ "Wikipedia:Arteriole" ] @@ -28688,7 +28625,7 @@ "val" : "vascular tree organ region", "xrefs" : [ "FMA:50722" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "vas sanguineum", "xrefs" : [ "Wikipedia:Blood_vessel" ] @@ -29112,7 +29049,7 @@ "pred" : "hasExactSynonym", "val" : "right cardiac atrium" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "atrium dextrum", "xrefs" : [ "Wikipedia:Right_atrium" ] @@ -29297,6 +29234,8 @@ "val" : "MA:0002986" }, { "val" : "MAT:0000148" + }, { + "val" : "MESH:D013131" }, { "val" : "MIAA:0000148" }, { @@ -29352,7 +29291,7 @@ "pred" : "hasNarrowSynonym", "val" : "paired fin skeleton" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "skeleton appendiculare", "xrefs" : [ "Wikipedia:Appendicular_skeleton" ] @@ -29809,7 +29748,7 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "cavitas thoracis", "xrefs" : [ "Wikipedia:Thoracic_cavity" ] @@ -29877,7 +29816,7 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "complexus juxtaglomerularis" }, { @@ -30089,7 +30028,7 @@ "val" : "notocord", "xrefs" : [ "ZFA:0000135" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "notochorda", "xrefs" : [ "Wikipedia:Notochord" ] @@ -30202,7 +30141,7 @@ "pred" : "hasRelatedSynonym", "val" : "somitic mesoderm" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "somitus", "xrefs" : [ "Wikipedia:Somite" ] @@ -30336,7 +30275,7 @@ "val" : "NC", "xrefs" : [ "XAO:0000048" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "crista neuralis", "xrefs" : [ "Wikipedia:Neural_crest" ] @@ -30430,7 +30369,7 @@ "pred" : "hasExactSynonym", "val" : "neuroectoderm" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "epithelium tubi neuralis; neuroectoderma", "xrefs" : [ "Wikipedia:Neuroectoderm" ] @@ -30870,7 +30809,7 @@ "val" : "ectoblast", "xrefs" : [ "MP:0003886" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "epiblastus", "xrefs" : [ "Wikipedia:Epiblast" ] @@ -31017,7 +30956,7 @@ "val" : "archinephric duct", "xrefs" : [ "VHOG:0000082" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "ductus pronephricus", "xrefs" : [ "Wikipedia:Pronephric_duct" ] @@ -31164,7 +31103,7 @@ "val" : "intermediate plate mesoderm", "xrefs" : [ "https://orcid.org/0000-0002-6601-2165" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "mesenchyma intermedium", "xrefs" : [ "Wikipedia:Intermediate_mesoderm" ] @@ -31275,7 +31214,7 @@ "val" : "archinephric duct", "xrefs" : [ "VHOG:0000082", "Wikipedia:Wolffian_duct" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "ductus mesonephricus; ductus Wolffi", "xrefs" : [ "Wikipedia:Mesonephric_duct" ] @@ -31351,7 +31290,7 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "lamina neuralis", "xrefs" : [ "Wikipedia:Neural_plate" ] @@ -31429,7 +31368,7 @@ "val" : "somitic mesoderm", "xrefs" : [ "ISBN:9780878932504" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "mesoderma paraxiale", "xrefs" : [ "Wikipedia:Paraxial_mesoderm" ] @@ -31505,7 +31444,7 @@ "val" : "lateral plate mesenchyme", "xrefs" : [ "EHDAA2:0000919" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "mesoderma laminae lateralis", "xrefs" : [ "Wikipedia:Lateral_plate_mesoderm" ] @@ -31626,7 +31565,7 @@ "val" : "sclerotomes", "xrefs" : [ "TAO:0001080" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "sclerotomus", "xrefs" : [ "Wikipedia:Sclerotome" ] @@ -31745,7 +31684,7 @@ "pred" : "hasExactSynonym", "val" : "portion of mesenchyme tissue" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "mesenchyma", "xrefs" : [ "Wikipedia:Mesenchyme" ] @@ -32486,7 +32425,7 @@ "val" : "kidney collecting duct system", "xrefs" : [ "Wikipedia:Collecting_duct_system" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "tubulus renalis colligens", "xrefs" : [ "Wikipedia:Collecting_duct_system" ] @@ -33131,6 +33070,8 @@ } ], "xrefs" : [ { "val" : "EMAPA:27756" + }, { + "val" : "VO:0010896" }, { "val" : "ZFA:0005589" } ], @@ -33185,7 +33126,7 @@ "val" : "pyramid of Malpighi", "xrefs" : [ "UBERON:cjm" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "pyramides renales", "xrefs" : [ "Wikipedia:Renal_pyramids" ] @@ -33283,7 +33224,7 @@ "val" : "outer stripe of renal medulla", "xrefs" : [ "FMA:76662" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "stria externa medullae renalis", "xrefs" : [ "FMA:76662", "FMA:TA" ] @@ -33820,7 +33761,7 @@ "val" : "An endothelium that lines the blood vasculature. Other endothelia may line lymph vessels, the heart.", "xrefs" : [ "https://orcid.org/0000-0002-6601-2165" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], + "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#vertebrate_core" ], "xrefs" : [ { "val" : "BTO:0000766" }, { @@ -33839,6 +33780,9 @@ "val" : "ZFA:0005257" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/RO_0002175", + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "uberon" } ] @@ -33866,7 +33810,7 @@ "val" : "afferent glomerular arteriole of kidney", "xrefs" : [ "FMA:77042" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "arteriola glomerularis afferens renis", "xrefs" : [ "FMA:77042", "FMA:TA" ] @@ -33875,7 +33819,7 @@ "val" : "kidney afferent arteriole", "xrefs" : [ "MP:0011312" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "arteriola glomerularis afferens", "xrefs" : [ "Wikipedia:Afferent_arterioles" ] @@ -33965,12 +33909,12 @@ "val" : "kidney interlobular artery", "xrefs" : [ "MP:0011316" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "arteriae corticales radiatae", "xrefs" : [ "Wikipedia:Interlobular_arteries" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "arteriae interlobulares renis", "xrefs" : [ "Wikipedia:Interlobular_arteries" ] @@ -34395,7 +34339,7 @@ }, "comments" : [ "part_of or develops_from urogenital ridge?" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "chorda nephrogenica", "xrefs" : [ "Wikipedia:Nephrogenic_cord" ] @@ -34761,7 +34705,7 @@ "type" : "CLASS", "meta" : { "definition" : { - "val" : ".", + "val" : "Missing definition for term UBERON:0005095. Please replace it using linked reference.", "xrefs" : [ "GO:0072003" ] }, "synonyms" : [ { @@ -34870,7 +34814,7 @@ "val" : "kidney connecting tubule", "xrefs" : [ "MA:0002610" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "tubulus renalis arcuatus", "xrefs" : [ "Wikipedia:Connecting_tubule" ] @@ -35697,7 +35641,7 @@ "val" : "basement membrane of connective tissue", "xrefs" : [ "FMA:63872" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "membrana basalis", "xrefs" : [ "Wikipedia:Basement_membrane" ] @@ -35857,7 +35801,7 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#pheno_slim", "http://purl.obolibrary.org/obo/uberon/core#uberon_slim" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "skeleton axiale", "xrefs" : [ "Wikipedia:Axial_skeleton" ] @@ -35914,7 +35858,7 @@ "pred" : "hasExactSynonym", "val" : "embryonic cloacal membrane" }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "membrana cloacalis", "xrefs" : [ "Wikipedia:Cloacal_membrane" ] @@ -37447,7 +37391,7 @@ "val" : "renal interlobar artery", "xrefs" : [ "MP:0011355" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "arteriae interlobares renis", "xrefs" : [ "Wikipedia:Interlobar_arteries" ] @@ -37494,7 +37438,7 @@ }, "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#upper_level" ], "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "lobus", "xrefs" : [ "FMA:45728", "FMA:TA" ] @@ -37535,7 +37479,7 @@ "val" : "lobus renalis", "xrefs" : [ "http://www.mondofacto.com/facts/dictionary?lobus+renalis" ] }, { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasRelatedSynonym", "val" : "lobi renales", "xrefs" : [ "Wikipedia:Renal_lobe" ] @@ -38058,7 +38002,7 @@ "val" : "A subdivision of an anatomical system.", "xrefs" : [ "http://orcid.org/0000-0002-6601-2165" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#common_anatomy", "http://purl.obolibrary.org/obo/uberon/core#upper_level" ], + "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#common_anatomy", "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#upper_level" ], "xrefs" : [ { "val" : "FBbt:00007330" }, { @@ -38075,6 +38019,9 @@ }, { "pred" : "http://purl.obolibrary.org/obo/RO_0002175", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_4751" + }, { + "pred" : "http://purl.obolibrary.org/obo/RO_0002175", + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "uberon" @@ -38377,7 +38324,7 @@ "xrefs" : [ "http://orcid.org/0000-0002-6601-2165" ] }, "synonyms" : [ { - "synonymType" : "http://purl.obolibrary.org/obo/uberon/core#LATIN", + "synonymType" : "http://purl.obolibrary.org/obo/OMO_0003011", "pred" : "hasExactSynonym", "val" : "sulcus urethralis primarius", "xrefs" : [ "Wikipedia:Urethral_groove" ] @@ -38466,7 +38413,7 @@ "val" : "The region of the organism associated with the visceral organs.", "xrefs" : [ "AEO:0000103" ] }, - "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas", "http://purl.obolibrary.org/obo/uberon/core#non_informative" ], + "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#non_informative" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "body", @@ -38486,9 +38433,6 @@ "val" : "FMA:231424" } ], "basicPropertyValues" : [ { - "pred" : "http://purl.obolibrary.org/obo/RO_0002175", - "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" - }, { "pred" : "http://purl.obolibrary.org/obo/UBPROP_0000001", "val" : "Cardinal body part, which consists of a maximal set of diverse subclasses of organ and organ part spatially associated with the vertebral column and ribcage. Examples: There is only one body proper[FMA:231424]." }, { @@ -39054,6 +38998,7 @@ "val" : "The upper tract of the renal system. The renal pelvis is the large cavity in the middle of each kidney. Urine drains from each kidney through a long tube called the ureter, into the bladder, where it is stored until it is passed from the body through the urethra.", "xrefs" : [ "NCIT:C54419" ] }, + "subsets" : [ "http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "renal pelvis and ureter" @@ -39065,6 +39010,9 @@ "val" : "NCIT:C54419" } ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/RO_0002175", + "val" : "http://purl.obolibrary.org/obo/NCBITaxon_9606" + }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "uberon" } ] @@ -39185,8 +39133,10 @@ "val" : "OBSOLETE A relation between a cell and molecule or complex such that every instance of the cell has a high number of instances of that molecule expressed on the cell surface. For the formal definition, see Masci et al (PMID:19243617).", "xrefs" : [ "PMID:19243617" ] }, - "comments" : [ "Replaced with RO:0015015, see https://github.com/obophenotype/cell-ontology/issues/1481" ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/obophenotype/cell-ontology/issues/1481" + }, { "pred" : "http://purl.obolibrary.org/obo/IAO_0100001", "val" : "http://purl.obolibrary.org/obo/RO_0015015" } ], @@ -39201,8 +39151,10 @@ "val" : "OBSOLETE A relation between a cell and molecule or complex such that every instance of the cell has a low number of instances of that molecule expressed on the cell surface. For the formal definition, see Masci et al (PMID:19243617).", "xrefs" : [ "PMID:19243617" ] }, - "comments" : [ "Replaced with RO:0015016, see https://github.com/obophenotype/cell-ontology/issues/1481" ], "basicPropertyValues" : [ { + "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", + "val" : "https://github.com/obophenotype/cell-ontology/issues/1481" + }, { "pred" : "http://purl.obolibrary.org/obo/IAO_0100001", "val" : "http://purl.obolibrary.org/obo/RO_0015016" } ], @@ -39432,13 +39384,12 @@ "lbl" : "transitively anteriorly connected to", "type" : "PROPERTY", "meta" : { - "definition" : { - "val" : ".", - "xrefs" : [ "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" ] - }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "uberon" + }, { + "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", + "val" : "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" } ] } }, { @@ -39446,13 +39397,12 @@ "lbl" : "transitively distally connected to", "type" : "PROPERTY", "meta" : { - "definition" : { - "val" : ".", - "xrefs" : [ "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" ] - }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "uberon" + }, { + "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", + "val" : "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" } ] } }, { @@ -39460,13 +39410,12 @@ "lbl" : "transitively proximally connected to", "type" : "PROPERTY", "meta" : { - "definition" : { - "val" : ".", - "xrefs" : [ "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" ] - }, "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "uberon" + }, { + "pred" : "http://www.w3.org/2000/01/rdf-schema#seeAlso", + "val" : "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" } ] } }, { @@ -40312,10 +40261,6 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0000547", "pred" : "http://purl.obolibrary.org/obo/BFO_0000051", "obj" : "http://purl.obolibrary.org/obo/CL_0017503" - }, { - "sub" : "http://purl.obolibrary.org/obo/CL_0000547", - "pred" : "http://purl.obolibrary.org/obo/BFO_0000051", - "obj" : "http://purl.obolibrary.org/obo/CL_0017505" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000547", "pred" : "http://purl.obolibrary.org/obo/BFO_0000051", @@ -40364,6 +40309,10 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0000547", "pred" : "http://purl.obolibrary.org/obo/CL_4030046", "obj" : "http://purl.obolibrary.org/obo/PR_000002978" + }, { + "sub" : "http://purl.obolibrary.org/obo/CL_0000547", + "pred" : "http://purl.obolibrary.org/obo/RO_0000053", + "obj" : "http://purl.obolibrary.org/obo/PATO_0040072" }, { "sub" : "http://purl.obolibrary.org/obo/CL_0000547", "pred" : "http://purl.obolibrary.org/obo/RO_0002104", @@ -41232,14 +41181,6 @@ "sub" : "http://purl.obolibrary.org/obo/CL_0017504", "pred" : "http://purl.obolibrary.org/obo/RO_0000053", "obj" : "http://purl.obolibrary.org/obo/PATO_0070047" - }, { - "sub" : "http://purl.obolibrary.org/obo/CL_0017505", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/GO_0005634" - }, { - "sub" : "http://purl.obolibrary.org/obo/CL_0017505", - "pred" : "http://purl.obolibrary.org/obo/RO_0000053", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000586" }, { "sub" : "http://purl.obolibrary.org/obo/CL_1000449", "pred" : "is_a", @@ -44340,18 +44281,6 @@ "sub" : "http://purl.obolibrary.org/obo/PATO_0000052", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/PATO_0000051" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0000068", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000001" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0000069", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000068" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0000117", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000051" }, { "sub" : "http://purl.obolibrary.org/obo/PATO_0000141", "pred" : "is_a", @@ -44364,18 +44293,6 @@ "sub" : "http://purl.obolibrary.org/obo/PATO_0000411", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/PATO_0000947" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0000461", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000068" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0000586", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000117" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0000586", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0002305" }, { "sub" : "http://purl.obolibrary.org/obo/PATO_0000947", "pred" : "is_a", @@ -44524,22 +44441,6 @@ "sub" : "http://purl.obolibrary.org/obo/PATO_0002299", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/PATO_0002078" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0002300", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000069" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0002300", - "pred" : "http://purl.obolibrary.org/obo/RO_0015007", - "obj" : "http://purl.obolibrary.org/obo/PATO_0000461" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0002305", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0001241" - }, { - "sub" : "http://purl.obolibrary.org/obo/PATO_0002305", - "pred" : "is_a", - "obj" : "http://purl.obolibrary.org/obo/PATO_0002300" }, { "sub" : "http://purl.obolibrary.org/obo/PATO_0002309", "pred" : "is_a", @@ -44572,6 +44473,10 @@ "sub" : "http://purl.obolibrary.org/obo/PATO_0015008", "pred" : "is_a", "obj" : "http://purl.obolibrary.org/obo/PATO_0000141" + }, { + "sub" : "http://purl.obolibrary.org/obo/PATO_0040072", + "pred" : "is_a", + "obj" : "http://purl.obolibrary.org/obo/PATO_0001396" }, { "sub" : "http://purl.obolibrary.org/obo/PATO_0070044", "pred" : "is_a", @@ -52781,9 +52686,6 @@ "restrictions" : [ { "propertyId" : "http://purl.obolibrary.org/obo/BFO_0000051", "fillerId" : "http://purl.obolibrary.org/obo/CL_0017503" - }, { - "propertyId" : "http://purl.obolibrary.org/obo/BFO_0000051", - "fillerId" : "http://purl.obolibrary.org/obo/CL_0017505" }, { "propertyId" : "http://purl.obolibrary.org/obo/BFO_0000051", "fillerId" : "http://purl.obolibrary.org/obo/GO_0005730" @@ -52823,6 +52725,9 @@ }, { "propertyId" : "http://purl.obolibrary.org/obo/RO_0000053", "fillerId" : "http://purl.obolibrary.org/obo/PATO_0002505" + }, { + "propertyId" : "http://purl.obolibrary.org/obo/RO_0000053", + "fillerId" : "http://purl.obolibrary.org/obo/PATO_0040072" }, { "propertyId" : "http://purl.obolibrary.org/obo/RO_0002104", "fillerId" : "http://purl.obolibrary.org/obo/PR_000001945" @@ -53245,13 +53150,6 @@ "propertyId" : "http://purl.obolibrary.org/obo/RO_0000053", "fillerId" : "http://purl.obolibrary.org/obo/PATO_0070047" } ] - }, { - "definedClassId" : "http://purl.obolibrary.org/obo/CL_0017505", - "genusIds" : [ "http://purl.obolibrary.org/obo/GO_0005634" ], - "restrictions" : [ { - "propertyId" : "http://purl.obolibrary.org/obo/RO_0000053", - "fillerId" : "http://purl.obolibrary.org/obo/PATO_0000586" - } ] }, { "definedClassId" : "http://purl.obolibrary.org/obo/CL_1000449", "genusIds" : [ "http://purl.obolibrary.org/obo/CL_0000066" ], @@ -54424,27 +54322,6 @@ "propertyId" : "http://purl.obolibrary.org/obo/RO_0002588", "fillerId" : "http://purl.obolibrary.org/obo/GO_0035869" } ] - }, { - "definedClassId" : "http://purl.obolibrary.org/obo/PATO_0000586", - "genusIds" : [ "http://purl.obolibrary.org/obo/PATO_0000117" ], - "restrictions" : [ { - "propertyId" : "http://purl.obolibrary.org/obo/RO_0015007", - "fillerId" : "http://purl.obolibrary.org/obo/PATO_0000461" - } ] - }, { - "definedClassId" : "http://purl.obolibrary.org/obo/PATO_0002300", - "genusIds" : [ "http://purl.obolibrary.org/obo/PATO_0000001" ], - "restrictions" : [ { - "propertyId" : "http://purl.obolibrary.org/obo/RO_0015007", - "fillerId" : "http://purl.obolibrary.org/obo/PATO_0000461" - } ] - }, { - "definedClassId" : "http://purl.obolibrary.org/obo/PATO_0002305", - "genusIds" : [ "http://purl.obolibrary.org/obo/PATO_0001241" ], - "restrictions" : [ { - "propertyId" : "http://purl.obolibrary.org/obo/RO_0015007", - "fillerId" : "http://purl.obolibrary.org/obo/PATO_0000461" - } ] }, { "definedClassId" : "http://purl.obolibrary.org/obo/PR_000029032", "genusIds" : [ "http://purl.obolibrary.org/obo/PR_000000001" ], diff --git a/subsets/kidney_upper_slim.obo b/subsets/kidney_upper_slim.obo index b7ccbe436..161bb5549 100644 --- a/subsets/kidney_upper_slim.obo +++ b/subsets/kidney_upper_slim.obo @@ -1,5 +1,5 @@ format-version: 1.2 -data-version: cl/releases/2024-01-04/subsets/kidney_upper_slim.owl +data-version: cl/releases/2024-02-13/subsets/kidney_upper_slim.owl subsetdef: abnormal_slim "" subsetdef: added_for_HCA "" subsetdef: attribute_slim "" @@ -31,6 +31,7 @@ subsetdef: goslim_mouse "" subsetdef: goslim_pir "" subsetdef: goslim_plant "" subsetdef: goslim_pombe "" +subsetdef: goslim_prokaryote "" subsetdef: goslim_synapse "" subsetdef: goslim_yeast "" subsetdef: grouping_class "" @@ -49,7 +50,6 @@ subsetdef: non_informative "" subsetdef: organ_slim "" subsetdef: pheno_slim "" subsetdef: phenotype_rcn "" -subsetdef: prokaryote_subset "" subsetdef: ro-eco "" subsetdef: RO:0002259 "" subsetdef: scalar_slim "" @@ -62,7 +62,6 @@ subsetdef: vertebrate_core "" synonymtypedef: blast_name "" synonymtypedef: COMPARATIVE_PREFERRED "" synonymtypedef: DEPRECATED "" -synonymtypedef: DUBIOUS "" synonymtypedef: equivalent_name "" synonymtypedef: genbank_common_name "" synonymtypedef: Gene-based "" @@ -71,13 +70,14 @@ synonymtypedef: HUMAN_PREFERRED "" synonymtypedef: HUMAN_PREFERRED "preferred term when talking about an instance of this class in Homo sapiens" synonymtypedef: in_part "" synonymtypedef: INCONSISTENT "" -synonymtypedef: LATIN "" synonymtypedef: LATIN "latin term" synonymtypedef: MISSPELLING "a mis-spelling that is in common use and thus recorded" synonymtypedef: NON_MAMMAL "" synonymtypedef: OMO:0003000 "abbreviation" +synonymtypedef: OMO:0003002 "" synonymtypedef: OMO:0003003 "" synonymtypedef: OMO:0003004 "plural form" +synonymtypedef: OMO:0003011 "" synonymtypedef: PENDING_REVIEW "" synonymtypedef: PLURAL "plural term" synonymtypedef: PRO-short-label "" @@ -88,7 +88,7 @@ synonymtypedef: synonym "" synonymtypedef: SYSTEMATIC "" synonymtypedef: systematic_synonym "" ontology: cl/subsets/kidney_upper_slim -property_value: owl:versionInfo "2024-01-04" xsd:string +property_value: owl:versionInfo "2024-02-13" xsd:string [Term] id: BFO:0000002 @@ -144,6 +144,7 @@ id: CL:0000000 name: cell def: "A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane." [CARO:mah] comment: The definition of cell is intended to represent all cells, and thus a cell is defined as a material entity and not an anatomical structure, which implies that it is part of an organism (or the entirety of one). +subset: cellxgene_subset subset: ubprop:upper_level xref: CALOHA:TS-2035 xref: FBbt:00007002 @@ -171,6 +172,7 @@ id: CL:0000034 name: stem cell def: "A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells." [GOC:tfm, MESH:D013234] comment: This term applies to metazoan. For plant stem cells, consider using PO:0004011 ‘initial cell’ or its parent PO:0004010 ‘meristematic cell’. +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "animal stem cell" EXACT [] @@ -189,6 +191,7 @@ name: hematopoietic stem cell def: "A stem cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system. Hematopoietic stem cells lack cell markers of effector cells (lin-negative). Lin-negative is defined by lacking one or more of the following cell surface markers: CD2, CD3 epsilon, CD4, CD5 ,CD8 alpha chain, CD11b, CD14, CD19, CD20, CD56, ly6G, ter119." [GOC:add, GOC:dsd, GOC:tfm, http://en.wikipedia.org/wiki/Hematopoietic_stem_cell, PMID:19022770] comment: Markers differ between species, and two sets of markers have been described for mice. HSCs are reportedly CD34-positive, CD45-positive, CD48-negative, CD150-positive, CD133-positive, and CD244-negative. subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "blood forming stem cell" EXACT [] synonym: "colony forming unit hematopoietic" RELATED [] @@ -238,6 +241,7 @@ id: CL:0000038 name: erythroid progenitor cell def: "A progenitor cell committed to the erythroid lineage." [GOC:add, ISBN:0721601464] subset: blood_and_immune_upper_slim +subset: cellxgene_subset synonym: "BFU-E" RELATED OMO:0003000 [] synonym: "blast forming unit erythroid" RELATED [] synonym: "burst forming unit erythroid" RELATED [] @@ -279,6 +283,7 @@ id: CL:0000049 name: common myeloid progenitor def: "A progenitor cell committed to myeloid lineage, including the megakaryocyte and erythroid lineages." [GOC:add, ISBN:0878932437, MESH:D023461] comment: This cell type is intended to be compatible with any vertebrate common myeloid progenitor. For mammalian CMP known to be CD34-positive, please use the term 'common myeloid progenitor, CD34-positive' (CL_0001059). +subset: cellxgene_subset subset: human_reference_atlas synonym: "CFU-GEMM" RELATED OMO:0003000 [ISBN:0878932437] synonym: "CFU-S" RELATED OMO:0003000 [ISBN:0878932437] @@ -298,6 +303,7 @@ id: CL:0000050 name: megakaryocyte-erythroid progenitor cell def: "A progenitor cell committed to the megakaryocyte and erythroid lineages." [GOC:add, GOC:dsd, GOC:tfm, http://en.wikipedia.org/wiki/Megakaryocyte-erythroid_progenitor_cell, MESH:D055015, PMID:16647566] comment: MEPs are reportedly CD19-negative, CD34-negative, CD45RA-negative, CD110-positive, CD117-positive, and SCA1-negative and reportedly express the transcription factors GATA-1 and NF-E2. +subset: cellxgene_subset subset: human_reference_atlas synonym: "CFU-EM" EXACT [] synonym: "CFU-MegE" EXACT [] @@ -330,6 +336,7 @@ id: CL:0000055 name: non-terminally differentiated cell def: "A precursor cell with a limited number of potential fates." [SANBI:mhl] comment: define using PATO mulit-potent or oligopotent? +subset: cellxgene_subset synonym: "blast cell" EXACT [] xref: BTO:0000125 xref: FMA:84782 @@ -351,6 +358,7 @@ id: CL:0000057 name: fibroblast def: "A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped." [http://en.wikipedia.org/wiki/Fibroblast, ISBN:0517223651, MESH:D005347] comment: These cells may be vimentin-positive, fibronectin-positive, fsp1-positive, MMP-1-positive, collagen I-positive, collagen III-positive, and alpha-SMA-negative. +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas xref: BTO:0000452 @@ -366,6 +374,7 @@ relationship: present_in_taxon NCBITaxon:9606 id: CL:0000064 name: ciliated cell def: "A cell that has a filiform extrusion of the cell surface." [GOC:tfm] +subset: cellxgene_subset xref: VHOG:0001532 xref: XAO:0000031 is_a: CL:0000000 ! cell @@ -378,6 +387,7 @@ relationship: has_part GO:0005929 ! cilium id: CL:0000066 name: epithelial cell def: "A cell that is usually found in a two-dimensional sheet with a free surface. The cell has a cytoskeleton that allows for tight cell to cell contact and for cell polarity where apical part is directed towards the lumen and the basal part to the basal lamina." [FB:ma, GOC:tfm, MESH:D004847] +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "epitheliocyte" EXACT [] @@ -396,6 +406,7 @@ property_value: depiction "https://www.swissbiopics.org/api/image/Epithelial_cel id: CL:0000067 name: ciliated epithelial cell def: "An epithelial cell that has a cilia." [GOC:tfm] +subset: cellxgene_subset xref: FMA:70605 is_a: CL:0000064 ! ciliated cell is_a: CL:0000066 ! epithelial cell @@ -406,6 +417,7 @@ intersection_of: has_part GO:0005929 ! cilium id: CL:0000068 name: duct epithelial cell def: "An epithelial cell that is part of a duct." [https://orcid.org/0000-0001-5208-3432] +subset: cellxgene_subset is_a: CL:0000066 ! epithelial cell intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0000058 ! duct @@ -415,6 +427,7 @@ relationship: part_of UBERON:0000058 ! duct id: CL:0000071 name: blood vessel endothelial cell def: "An endothelial cell that lines the vasculature." [GOC:tfm] +subset: cellxgene_subset subset: human_reference_atlas synonym: "cuboidal endothelial cell of vascular tree" EXACT [] is_a: CL:0000076 {is_inferred="true"} ! squamous epithelial cell @@ -435,6 +448,7 @@ is_a: CL:0002078 ! meso-epithelial cell id: CL:0000075 name: columnar/cuboidal epithelial cell def: "A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube." [GO:0002065, https://orcid.org/0000-0001-5208-3432] +subset: cellxgene_subset subset: human_reference_atlas is_a: CL:0000066 ! epithelial cell relationship: present_in_taxon NCBITaxon:9606 @@ -442,6 +456,7 @@ relationship: present_in_taxon NCBITaxon:9606 [Term] id: CL:0000076 name: squamous epithelial cell +subset: cellxgene_subset xref: CALOHA:TS-1249 is_a: CL:0000066 ! epithelial cell @@ -449,6 +464,7 @@ is_a: CL:0000066 ! epithelial cell id: CL:0000081 name: blood cell def: "A cell found predominately in the blood." [GOC:add, GOC:tfm] +subset: cellxgene_subset subset: general_cell_types_upper_slim xref: FMA:62844 xref: MESH:D001773 @@ -462,6 +478,7 @@ id: CL:0000115 name: endothelial cell def: "An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal. In mammals, endothelial cell has vimentin filaments and is derived from the mesoderm." [GOC:tfm, http://en.wikipedia.org/wiki/Endothelial_cell, https://sourceforge.net/tracker/?func=detail&atid=440764&aid=3364936&group_id=36855, MESH:D042783, PMID:21275341] comment: From FMA: 9.07.2001: Endothelial cell has always been classified as a kind of epithelial cell, specifically a squamous cell but that is not true. First, endothelial cell can either be squamous or cuboidal (e.g. high-endothelial cell) and secondly, it has different embryological derivation (mesodermal) than a true epithelial cell (ectodermal and endodermal). The basis for present classification is the fact that it comprises the outermost layer or lining of anatomical structures (location-based) but a better structural basis for the differentia is the cytoskeleton of the cell. Endothelial cell has vimentin filaments while an epithelial cell has keratin filaments. [Onard]. +subset: cellxgene_subset subset: human_reference_atlas synonym: "endotheliocyte" EXACT [] xref: BTO:0001176 @@ -483,6 +500,7 @@ id: CL:0000134 name: mesenchymal stem cell def: "A connective tissue cell that normally gives rise to other cells that are organized as three-dimensional masses. In humans, this cell type is CD73-positive, CD90-positive, CD105-positive, CD45-negative, CD34-negative, and MHCII-negative. They may further differentiate into osteoblasts, adipocytes, myocytes, neurons, or chondroblasts in vitro. Originally described as residing in the bone marrow, this cell type is now known to reside in many, if not all, adult organs." [FB:ma, GOC:dsd, http://en.wikipedia.org/wiki/Mesenchymal_stem_cell, http://www.copewithcytokines.de/cope.cgi?key=mesenchymal%20stem%20cells, PMCID:PMC2613570, PMID:10102814, PMID:16923606, PMID:17986482, PMID:19960544] comment: Many but not all mesenchymal cells derive from the mesoderm. MSCs are reportedly CD3-negative, CD4-negative, CD5-negative, CD8-negative, CD11a-negative, CD11b-negative, CD14-negative, CD19-negative, CD29-positive, CD31-negative, CD34-negative, CD38-negative, CD40-negative, CD44-positive, CD45-negative, CD49-positive, CD54-positive, CD66b-negative, CD79a-negative, CD80-negative, CD102-positive, CD106-positive, CD117-positive, CD121a-positive, CD121b-positive, CD123-positive, CD124-positive, CD133-negative, CD146-positive, CD166-positive, CD271-positive, B220-negative, Gr1-negative, MHCI-positive, MHCII-negative, SSEA4-negative, sca1-positive, Ter119-negative, and glycophorin A-negative. Cultured MSCs are capable of producing stem cell factor, IL7, IL8, IL11, TGF-beta, cofilin, galectin-1, laminin-receptor 1, cyclophilin A, and MMP-2. +subset: cellxgene_subset synonym: "BMSC" RELATED OMO:0003000 [] synonym: "bone marrow stromal cells" NARROW [] synonym: "CFU-F" RELATED OMO:0003000 [] @@ -506,6 +524,7 @@ property_value: seeAlso "https://github.com/obophenotype/cell-ontology/issues/47 id: CL:0000151 name: secretory cell def: "A cell that specializes in controlled release of one or more substances." [GOC:tfm, ISBN:0721662544] +subset: cellxgene_subset xref: BTO:0003659 xref: FMA:86916 is_a: CL:0000000 ! cell @@ -525,12 +544,14 @@ relationship: capable_of GO:0009306 ! protein secretion id: CL:0000183 name: contractile cell def: "A cell whose primary function is to shorten." [FB:ma] +subset: cellxgene_subset is_a: CL:0000000 ! cell [Term] id: CL:0000187 name: muscle cell def: "A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns." [MESH:D032342] +subset: cellxgene_subset synonym: "muscle fiber" EXACT [] synonym: "myocyte" EXACT [] xref: BTO:0000888 @@ -548,6 +569,7 @@ property_value: depiction "https://www.swissbiopics.org/api/image/Muscle_cells.s id: CL:0000192 name: smooth muscle cell def: "A non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels. They develop from specialized myoblasts (smooth muscle myoblast)." [http://en.wikipedia.org/wiki/Smooth_muscle_cell, MESH:D032389, PMID:9315361] +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "myocytes, smooth muscle" EXACT [MESH:D032389] @@ -603,6 +625,7 @@ relationship: part_of UBERON:0000924 ! ectoderm id: CL:0000222 name: mesodermal cell def: "A cell of the middle germ layer of the embryo." [MESH:D008648] +subset: cellxgene_subset synonym: "mesoblast" EXACT [] synonym: "mesoderm cell" EXACT [] xref: FMA:72554 @@ -623,6 +646,7 @@ id: CL:0000232 name: erythrocyte def: "A red blood cell. In mammals, mature erythrocytes are biconcave disks containing hemoglobin whose function is to transport oxygen." [GOC:tfm, MESH:D004912] subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "RBC" EXACT [] synonym: "red blood cell" EXACT [] @@ -653,6 +677,7 @@ is_a: CL:0000075 ! columnar/cuboidal epithelial cell [Term] id: CL:0000255 name: eukaryotic cell +subset: cellxgene_subset xref: MESH:D005057 is_a: CL:0000000 ! cell intersection_of: CL:0000000 ! cell @@ -720,19 +745,21 @@ is_a: CL:0000211 ! electrically active cell id: CL:0000514 name: smooth muscle myoblast def: "A precursor cell destined to differentiate into smooth muscle myocytes." [GOC:tfm, MESH:D032390] +subset: cellxgene_subset synonym: "myoblast, smooth muscle" EXACT [MESH:D032390] synonym: "satellite cell" RELATED [] xref: FMA:84798 is_a: CL:0000056 ! myoblast intersection_of: CL:0000056 ! myoblast -intersection_of: RO:0002203 CL:0000192 ! develops into smooth muscle cell -relationship: RO:0002203 CL:0000192 ! develops into smooth muscle cell +intersection_of: develops_into CL:0000192 ! smooth muscle cell +relationship: develops_into CL:0000192 ! smooth muscle cell [Term] id: CL:0000540 name: neuron def: "The basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system." [http://en.wikipedia.org/wiki/Neuron, MESH:D009474] comment: These cells are also reportedly CD4-negative and CD200-positive. They are also capable of producing CD40L and IFN-gamma. +subset: cellxgene_subset subset: general_cell_types_upper_slim subset: human_reference_atlas synonym: "nerve cell" EXACT [] @@ -754,6 +781,7 @@ id: CL:0000547 name: proerythroblast def: "An immature, nucleated erythrocyte occupying the stage of erythropoeisis that follows formation of erythroid progenitor cells. This cell is CD71-positive, has both a nucleus and a nucleolus, and lacks hematopoeitic lineage markers." [ISBN:0721601464, PMID:1638021] subset: blood_and_immune_upper_slim +subset: cellxgene_subset synonym: "pronormoblast" RELATED [] synonym: "rubriblast" EXACT [ISBN:0721601464] xref: FMA:83518 @@ -762,6 +790,7 @@ is_a: CL:0002242 ! nucleate cell is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000764 ! erythroid lineage cell intersection_of: bearer_of PATO:0002505 ! nucleated +intersection_of: bearer_of PATO:0040072 ! high nuclear/cytoplasmic ratio intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M @@ -774,9 +803,9 @@ intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell sur intersection_of: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule intersection_of: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G intersection_of: has_part CL:0017503 ! basophilic cytoplasm -intersection_of: has_part CL:0017505 ! increased nucleus size intersection_of: has_part GO:0005730 ! nucleolus intersection_of: RO:0002104 PR:000001945 ! has plasma membrane part transferrin receptor protein 1 +relationship: bearer_of PATO:0040072 ! high nuclear/cytoplasmic ratio relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M @@ -790,7 +819,6 @@ relationship: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule relationship: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G relationship: develops_from CL:0000038 ! erythroid progenitor cell relationship: has_part CL:0017503 ! basophilic cytoplasm -relationship: has_part CL:0017505 ! increased nucleus size relationship: has_part GO:0005730 ! nucleolus relationship: RO:0002104 PR:000001945 ! has plasma membrane part transferrin receptor protein 1 @@ -858,6 +886,7 @@ id: CL:0000553 name: megakaryocyte progenitor cell def: "The earliest cytologically identifiable precursor in the thrombocytic series. This cell is capable of endomitosis and lacks expression of hematopoieitic lineage markers (lin-negative)." [GOC:dsd, GOC:tfm, ISBN:0721601464] comment: Lineage negative is described here as CD2-negative, CD3-negative, CD4-negative, CD5-negative, CD8a-negative, CD14-negative, CD19-negative, CD20-negative, CD56-negative, Ly6g-negative, and Ter119-negative. +subset: cellxgene_subset subset: human_reference_atlas synonym: "CFU-Meg" EXACT [PMID:11722431, PMID:12482498] synonym: "colony-forming unit-megakaryocyte" EXACT [] @@ -913,6 +942,7 @@ name: megakaryocyte def: "A large hematopoietic cell (50 to 100 micron) with a lobated nucleus. Once mature, this cell undergoes multiple rounds of endomitosis and cytoplasmic restructuring to allow platelet formation and release." [http://en.wikipedia.org/wiki/Megakaryocyte, ISBN:0721601464, MESH:D008533, PMID:31043076] comment: Megakaryocytes are reportedly CD181-positive and CD182-positive. subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "megacaryocyte" EXACT [] synonym: "megalocaryocyte" EXACT [] @@ -931,6 +961,7 @@ id: CL:0000558 name: reticulocyte def: "An immature erythrocyte that changes the protein composition of its plasma membrane by exosome formation and extrusion. The types of protein removed differ between species though removal of the transferrin receptor is apparent in mammals and birds." [GOC:add, GOC:tfm, PMID:15946868, PMID:2037622] subset: blood_and_immune_upper_slim +subset: cellxgene_subset xref: BTO:0001173 xref: CALOHA:TS-0864 xref: MESH:D012156 @@ -988,6 +1019,7 @@ relationship: RO:0002104 PR:000016043 ! has plasma membrane part T-cell acute ly id: CL:0000586 name: germ cell def: "The reproductive cell in multicellular organisms." [MESH:D005854] +subset: cellxgene_subset xref: BTO:0000535 xref: NCIT:C12597 xref: VHOG:0001534 @@ -999,6 +1031,7 @@ relationship: capable_of_part_of GO:0009566 ! fertilization id: CL:0000630 name: supporting cell def: "A cell whose primary function is to support other cell types." [FB:ma, GOC:tfm] +subset: cellxgene_subset synonym: "supportive cell" EXACT [] xref: BTO:0002315 is_a: CL:0000000 ! cell @@ -1026,6 +1059,7 @@ id: CL:0000650 name: mesangial cell def: "A cell type that encapsulates the capillaries and venules in the kidney. This cell secretes mesangial matrix that provides the structural support for the capillaries." [GOC:tfm, http://www.copewithcytokines.de/cope.cgi?key=mesangial%20cells] comment: Do all of these cells really develop from some mesenchymal stem cell? +subset: cellxgene_subset synonym: "kidney mesangial cell" EXACT [] xref: BTO:0000853 xref: CALOHA:TS-0617 @@ -1037,6 +1071,7 @@ relationship: develops_from CL:0000134 ! mesenchymal stem cell [Term] id: CL:0000666 name: fenestrated cell +subset: cellxgene_subset synonym: "window cell" EXACT [] is_a: CL:0000066 ! epithelial cell @@ -1045,6 +1080,7 @@ id: CL:0000669 name: pericyte def: "An elongated, contractile cell found wrapped about precapillary arterioles outside the basement membrane. Pericytes are present in capillaries where proper adventitia and muscle layer are missing (thus distingushing this cell type from adventitial cells). They are relatively undifferentiated and may become fibroblasts, macrophages, or smooth muscle cells." [GOC:dsd, GOC:tfm, ISBN:0721662544, MESH:D020286, PMID:16807374, PMID:17986482, PMID:20024907] comment: Pericytes are CD10-positive, CD13-positive, CD31-negative, CD45-negative, CD106-positive, CD117-negative, CD140-positive, CD144-negative, CD146-positive, CD271-positive, CD325-positive, NG2-positive, RGS5-positive, SMA-positive, and desmin-positive. A subpopulation is CD248-positive. They are also capable of producing angiopoietin 1, CXCL12, TGF-beta, and VEGF-A. +subset: cellxgene_subset subset: human_reference_atlas synonym: "adventitial cell" RELATED [] synonym: "adventitial reticular cell" EXACT [] @@ -1064,11 +1100,12 @@ relationship: present_in_taxon NCBITaxon:9606 id: CL:0000680 name: muscle precursor cell def: "A non-terminally differentiated cell that is capable of developing into a muscle cell." [GOC:add] +subset: cellxgene_subset is_a: CL:0000055 ! non-terminally differentiated cell intersection_of: CL:0011115 ! precursor cell -intersection_of: RO:0002203 CL:0000187 ! develops into muscle cell +intersection_of: develops_into CL:0000187 ! muscle cell relationship: develops_from CL:0000222 ! mesodermal cell -relationship: RO:0002203 CL:0000187 ! develops into muscle cell +relationship: develops_into CL:0000187 ! muscle cell [Term] id: CL:0000723 @@ -1085,6 +1122,7 @@ relationship: capable_of GO:0048103 ! somatic stem cell division id: CL:0000763 name: myeloid cell def: "A cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage." [GOC:add] +subset: cellxgene_subset xref: BTO:0001441 xref: CALOHA:TS-0647 xref: MESH:D022423 @@ -1098,6 +1136,7 @@ id: CL:0000764 name: erythroid lineage cell def: "A immature or mature cell in the lineage leading to and including erythrocytes." [GOC:add, GOC:tfm] comment: Note that in FMA erythropoietic cells are types of nucleated erythrocytes and thus don't include erythrocytes. +subset: cellxgene_subset subset: human_reference_atlas synonym: "erythropoietic cell" EXACT [] xref: CALOHA:TS-0290 @@ -1111,6 +1150,7 @@ id: CL:0000765 name: erythroblast def: "A nucleated precursor of an erythrocyte that lacks hematopoietic lineage markers." [GOC:add, ISBN:0721601464, PMID:18174176] subset: blood_and_immune_upper_slim +subset: cellxgene_subset synonym: "normoblast" EXACT [] xref: BTO:0001571 xref: CALOHA:TS-0289 @@ -1155,6 +1195,7 @@ name: hematopoietic multipotent progenitor cell def: "A hematopoietic multipotent progenitor cell is multipotent, but not capable of long-term self-renewal. These cells are characterized as lacking lineage cell surface markers and being CD34-positive in both mice and humans." [GOC:add, GOC:tfm, PMID:19022770] comment: Markers differ between mouse and human. subset: blood_and_immune_upper_slim +subset: cellxgene_subset subset: human_reference_atlas synonym: "hemopoietic progenitor cell" EXACT [] synonym: "MPP" EXACT [] @@ -1202,6 +1243,7 @@ id: CL:0000839 name: myeloid lineage restricted progenitor cell def: "A progenitor cell restricted to the myeloid lineage." [GOC:add, GOC:tfm, PMID:19022770] comment: Note that this is a class of cell types, not an identified single cell type. +subset: cellxgene_subset subset: human_reference_atlas synonym: "myeloid progenitor cell" BROAD [] xref: BTO:0004730 @@ -1218,6 +1260,7 @@ relationship: present_in_taxon NCBITaxon:9606 id: CL:0000988 name: hematopoietic cell def: "A cell of a hematopoietic lineage." [GO_REF:0000031, GOC:add] +subset: cellxgene_subset synonym: "haematopoietic cell" EXACT [] synonym: "haemopoietic cell" EXACT [] synonym: "hemopoietic cell" EXACT [] @@ -1285,6 +1328,7 @@ id: CL:0002139 name: endothelial cell of vascular tree def: "An endothelial cell of the vascular tree, which includes blood vessels and lymphatic vessels." [GOC:dsd, GOC:tfm, PMID:12768659] comment: These cells are reportedly CD31-positive, CD34-positive, CD144-positive, TAL1-positive. +subset: cellxgene_subset synonym: "cubodial endothelial cell of vascular tree" NARROW [] synonym: "vascular endothelial cell" EXACT [] xref: BTO:0001854 @@ -1316,6 +1360,7 @@ creation_date: 2010-08-25T02:20:55Z id: CL:0002188 name: glomerular endothelial cell def: "An endothelial cell found in the glomerulus of the kidney. This cell is flattened, highly fenestrated, and plays a vital role in the formation of glomerular ultrafiltrate." [GOC:tfm, PMID:15840009] +subset: cellxgene_subset subset: kidney_upper_slim xref: BTO:0004632 xref: FMA:70970 @@ -1358,6 +1403,7 @@ relationship: part_of UBERON:0004135 ! distal tubule id: CL:0002306 name: epithelial cell of proximal tubule def: "An epithelial cell of the proximal tubule of the kidney." [GOC:tfm, ISBN:1-4160-2328-3] +subset: cellxgene_subset subset: human_reference_atlas subset: kidney_upper_slim synonym: "kidney proximal tubule epithelial cell" EXACT [] @@ -1376,6 +1422,7 @@ relationship: present_in_taxon NCBITaxon:9606 id: CL:0002319 name: neural cell def: "A cell that is part of the nervous system." [GOC:tfm, ISBN:0618947256] +subset: cellxgene_subset xref: CALOHA:TS-2040 xref: FMA:70333 is_a: CL:0000000 ! cell @@ -1389,6 +1436,7 @@ creation_date: 2010-09-15T01:34:57Z id: CL:0002320 name: connective tissue cell def: "A cell of the supporting or framework tissue of the body, arising chiefly from the embryonic mesoderm and including adipose tissue, cartilage, and bone." [GOC:tfm, ISBN:0618947256] +subset: cellxgene_subset xref: CALOHA:TS-2096 xref: FMA:63875 xref: MESH:D003239 @@ -1431,6 +1479,7 @@ creation_date: 2010-12-07T09:37:22Z id: CL:0002518 name: kidney epithelial cell def: "An epithelial cell of the kidney." [GOC:tfm, KUPO:SJ] +subset: cellxgene_subset xref: KUPO:0001019 is_a: CL:0000066 ! epithelial cell is_a: CL:1000497 {is_inferred="true"} ! kidney cell @@ -1473,6 +1522,7 @@ creation_date: 2011-10-25T03:49:41Z id: CL:0005009 name: renal principal cell def: "A cuboidal epithelial cell of the kidney which regulates sodium and potassium balance. The activity of sodium and potassium channels on the apical membrane of the cell is regulated by aldosterone and vasopressin. In mammals this cell type is located in the renal collecting duct system." [CL:CVS] +subset: cellxgene_subset is_a: CL:0000075 ! columnar/cuboidal epithelial cell is_a: CL:0002518 ! kidney epithelial cell @@ -1496,6 +1546,7 @@ is_a: CL:0000187 ! muscle cell id: CL:0008001 name: hematopoietic precursor cell def: "Any hematopoietic cell that is a precursor of some other hematopoietic cell type." [GOC:dos] +subset: cellxgene_subset is_a: CL:0000988 ! hematopoietic cell [Term] @@ -1512,6 +1563,7 @@ relationship: part_of UBERON:8600004 ! visceral muscle tissue id: CL:0008019 name: mesenchymal cell def: "A non-polarised cell precursor cell that is part of some mesenchyme, is associated with the cell matrix but is not connected to other cells and is capable of migration." [] +subset: cellxgene_subset subset: human_reference_atlas synonym: "mesenchyme cell" EXACT [] is_a: CL:0000219 ! motile cell @@ -1524,6 +1576,7 @@ id: CL:0008034 name: mural cell def: "Mural cells are pericytes and the vascular smooth muscle cells (vSMCs) of the microcirculation." [Wiki:Mural_cell&oldid=930603194] subset: added_for_HCA +subset: cellxgene_subset subset: human_reference_atlas is_a: CL:4033054 ! perivascular cell relationship: dc-contributor https://orcid.org/0000-0002-7073-9172 @@ -1542,6 +1595,7 @@ relationship: seeAlso https://github.com/obophenotype/cell-ontology/issues/786 id: CL:0011012 name: neural crest cell def: "A cell of the neural crest. Neural crest cells are multipotent. Premigratory neural crest cells are found at the neural plate boarder, some of which will undergo ectomesynchymal transition and delamination to form migratory neural crest cells." [https://orcid.org/0000-0001-5208-3432, https://orcid.org/0000-0002-9900-7880] +subset: cellxgene_subset is_a: CL:0000048 ! multi fate stem cell is_a: CL:0002321 ! embryonic cell (metazoa) @@ -1549,6 +1603,7 @@ is_a: CL:0002321 ! embryonic cell (metazoa) id: CL:0011026 name: progenitor cell def: "A precursor cell that has a tendency to differentiate into a specific type of cell. They are descendants of stem cells, only they are more constrained in their differentiation potential or capacity for self-renewal, and are often more limited in both senses." [https://doi.org/10.1016/B978-0-12-409503-8.00002-0, ISBN:978-1-62808-994-3] +subset: cellxgene_subset is_a: CL:0011115 ! precursor cell intersection_of: CL:0011115 ! precursor cell intersection_of: develops_from CL:0000034 ! stem cell @@ -1560,6 +1615,7 @@ id: CL:0011115 name: precursor cell def: "A cell that, by division or terminal differentiation, can give rise to other cell types." [GOC:dos] comment: Work is needed on GO 'cell differentiation' before it is clear whether the equivalent class definition 'native cell' that capable_of some 'cell differentiation' works. Also, may want to consider merging this with non-terminally differentiated cell. +subset: cellxgene_subset is_a: CL:0000000 ! cell intersection_of: CL:0000000 ! cell intersection_of: capable_of GO:0030154 ! cell differentiation @@ -1599,21 +1655,11 @@ relationship: bearer_of PATO:0070047 ! polychromatophilic relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2009-12-28T04:25:23Z -[Term] -id: CL:0017505 -name: increased nucleus size -def: "A nucleus size quality which is relatively high compared to the amount of cytoplasm present in the same cell." [GOC:tfm] -is_a: GO:0005634 ! nucleus -intersection_of: GO:0005634 ! nucleus -intersection_of: bearer_of PATO:0000586 ! increased size -relationship: bearer_of PATO:0000586 ! increased size -relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 -creation_date: 2009-12-23T10:53:24Z - [Term] id: CL:1000449 name: epithelial cell of nephron def: "An epithelial cell that is part of the nephron." [GOC:tfm] +subset: cellxgene_subset xref: FMA:70965 is_a: CL:0002518 ! kidney epithelial cell intersection_of: CL:0000066 ! epithelial cell @@ -1624,6 +1670,7 @@ relationship: part_of UBERON:0001285 ! nephron id: CL:1000450 name: epithelial cell of glomerular capsule def: "An epithelial cell that is part of the glomerular capsule." [GOC:tfm] +subset: cellxgene_subset subset: kidney_upper_slim synonym: "Bowmans capsule epithelial cell" EXACT [] synonym: "epithelial cell of Bowman's capsule" EXACT [FMA:70966] @@ -1638,6 +1685,7 @@ relationship: part_of UBERON:0001230 ! glomerular capsule id: CL:1000454 name: kidney collecting duct epithelial cell def: "An epithelial cell that is part of the collecting duct of renal tubule." [GOC:tfm] +subset: cellxgene_subset subset: human_reference_atlas subset: kidney_upper_slim synonym: "epithelial cell of renal collecting tubule" EXACT [FMA:70982] @@ -1655,6 +1703,7 @@ id: CL:1000494 name: nephron tubule epithelial cell def: "An epithelial cell that is part of a nephron tubule." [GOC:tfm] comment: This needs to be further defined as a juxtamedullary nephron. Will request the juxtamedullary nephron tubule class from UBERON. +subset: cellxgene_subset synonym: "kidney tubule epithelial cell" EXACT [] xref: FMA:86785 xref: KUPO:0001022 @@ -1668,6 +1717,7 @@ relationship: part_of UBERON:0004810 ! nephron tubule epithelium id: CL:1000497 name: kidney cell def: "A cell that is part of a kidney." [] +subset: cellxgene_subset xref: KUPO:0001010 is_a: CL:0000000 ! cell intersection_of: CL:0000000 ! cell @@ -1678,6 +1728,7 @@ relationship: part_of UBERON:0002113 ! kidney id: CL:1000500 name: kidney interstitial cell def: "A cell that is part of kidney interstitium." [] +subset: cellxgene_subset subset: kidney_upper_slim xref: KUPO:0001013 is_a: CL:1000497 ! kidney cell @@ -1721,6 +1772,7 @@ relationship: part_of UBERON:0001231 ! nephron tubule [Term] id: CL:1000510 name: kidney glomerular epithelial cell +subset: cellxgene_subset xref: KUPO:0001023 is_a: CL:1000746 ! glomerular cell intersection_of: CL:0002518 ! kidney epithelial cell @@ -1763,6 +1815,7 @@ relationship: part_of UBERON:0001229 ! renal corpuscle [Term] id: CL:1000615 name: kidney cortex tubule cell +subset: cellxgene_subset xref: KUPO:0001024 is_a: CL:0002584 ! renal cortical epithelial cell is_a: CL:1000449 ! epithelial cell of nephron @@ -1785,6 +1838,7 @@ relationship: part_of UBERON:0002303 ! juxtaglomerular apparatus [Term] id: CL:1000692 name: kidney interstitial fibroblast +subset: cellxgene_subset subset: human_reference_atlas xref: KUPO:0001102 is_a: CL:0000057 ! fibroblast @@ -1805,6 +1859,7 @@ relationship: part_of UBERON:0000074 ! renal glomerulus [Term] id: CL:1000768 name: kidney connecting tubule epithelial cell +subset: cellxgene_subset subset: human_reference_atlas subset: kidney_upper_slim xref: KUPO:0001058 @@ -1818,6 +1873,7 @@ relationship: present_in_taxon NCBITaxon:9606 [Term] id: CL:1000849 name: kidney distal convoluted tubule epithelial cell +subset: cellxgene_subset subset: human_reference_atlas subset: kidney_upper_slim xref: KUPO:0001056 @@ -1851,6 +1907,7 @@ relationship: part_of UBERON:0003644 ! kidney arterial blood vessel [Term] id: CL:1000892 name: kidney capillary endothelial cell +subset: cellxgene_subset subset: kidney_upper_slim xref: KUPO:0001030 is_a: CL:0000071 ! blood vessel endothelial cell @@ -1872,6 +1929,7 @@ relationship: part_of UBERON:0001140 ! renal vein [Term] id: CL:1000909 name: kidney loop of Henle epithelial cell +subset: cellxgene_subset xref: KUPO:0001047 is_a: CL:1000494 {is_inferred="true"} ! nephron tubule epithelial cell intersection_of: CL:1000494 ! nephron tubule epithelial cell @@ -1881,6 +1939,7 @@ relationship: part_of UBERON:0001288 ! loop of Henle [Term] id: CL:1001016 name: kidney loop of Henle ascending limb epithelial cell +subset: cellxgene_subset subset: kidney_upper_slim xref: KUPO:0001048 is_a: CL:0002305 ! epithelial cell of distal tubule @@ -1903,6 +1962,7 @@ relationship: part_of UBERON:0001289 ! descending limb of loop of Henle id: CL:1001225 name: kidney collecting duct cell def: "A cell that is part of a collecting duct of renal tubule." [] +subset: cellxgene_subset xref: KUPO:0001012 xref: Wikipedia:Kidney_collecting_duct_cell is_a: CL:1000497 ! kidney cell @@ -1914,6 +1974,7 @@ relationship: part_of UBERON:0001232 ! collecting duct of renal tubule id: CL:1001318 name: renal interstitial pericyte def: "A pericyte cell located in the kidney interstitium." [] +subset: cellxgene_subset subset: human_reference_atlas xref: KUPO:0001104 is_a: CL:0000669 {is_inferred="true"} ! pericyte @@ -2375,7 +2436,7 @@ id: GO:0005575 name: cellular_component namespace: cellular_component alt_id: GO:0008372 -def: "A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex)." [GOC:pdt] +def: "A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex)." [GOC:pdt] comment: Note that, in addition to forming the root of the cellular component ontology, this term is recommended for the annotation of gene products whose cellular component is unknown. When this term is used for annotation, it indicates that no information was available about the cellular component of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this. subset: goslim_candida subset: goslim_chembl @@ -2406,8 +2467,8 @@ subset: goslim_metagenomics subset: goslim_mouse subset: goslim_pir subset: goslim_plant +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset synonym: "extracellular" EXACT [] xref: Wikipedia:Extracellular is_a: GO:0110165 ! cellular anatomical entity @@ -2466,7 +2527,7 @@ comment: Note that for multicellular organisms, the extracellular space refers t subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "intercellular space" RELATED [] xref: NIF_Subcellular:sao1425028079 is_a: GO:0110165 ! cellular anatomical entity @@ -2530,8 +2591,8 @@ subset: goslim_flybase_ribbon subset: goslim_generic subset: goslim_metagenomics subset: goslim_pir +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset synonym: "chromatid" RELATED [] synonym: "interphase chromosome" NARROW [] synonym: "prophase chromosome" NARROW [] @@ -2565,8 +2626,8 @@ subset: goslim_chembl subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset xref: Wikipedia:Cytoplasm is_a: GO:0110165 ! cellular anatomical entity relationship: part_of GO:0005622 ! intracellular anatomical structure @@ -2641,8 +2702,8 @@ subset: goslim_generic subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset synonym: "free ribosome" NARROW [NIF_Subcellular:sao1139385046] synonym: "membrane bound ribosome" NARROW [NIF_Subcellular:sao1291545653] synonym: "ribosomal RNA" RELATED [] @@ -2666,8 +2727,8 @@ subset: goslim_generic subset: goslim_mouse subset: goslim_pir subset: goslim_plant +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset xref: Wikipedia:Cytoskeleton is_a: GO:0043232 ! intracellular non-membrane-bounded organelle @@ -2700,8 +2761,8 @@ subset: goslim_generic subset: goslim_metagenomics subset: goslim_mouse subset: goslim_plant +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset synonym: "bacterial inner membrane" NARROW [] synonym: "cell membrane" EXACT [] synonym: "cellular membrane" EXACT [NIF_Subcellular:sao6433132645] @@ -2793,7 +2854,7 @@ subset: goslim_drosophila subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "protein anabolism" EXACT [] synonym: "protein biosynthesis" EXACT [] synonym: "protein biosynthetic process" EXACT [] @@ -2865,7 +2926,7 @@ subset: goslim_chembl subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "single-organism transport" RELATED [] is_a: GO:0051234 ! establishment of localization property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/20292" xsd:anyURI @@ -2982,8 +3043,8 @@ subset: goslim_candida subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset synonym: "cytoskeletal organization and biogenesis" RELATED [GOC:mah] synonym: "cytoskeletal regulator activity" RELATED [] synonym: "cytoskeleton organisation" EXACT [] @@ -3306,7 +3367,7 @@ id: GO:0008219 name: cell death namespace: biological_process def: "Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538)." [GOC:mah, GOC:mtg_apoptosis, PMID:25236395] -comment: This term should not be used for direct annotation, it is currently kept in GO as a placeholder for describing cell death phenotypes in uPHENO. When information is provided on a programmed cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'). Unintentional cell death, i.e. cell death caused by injury, ageing, or cell phenotypes observed as a result of a pathological mutation in an essential gene should NOT be annotated using GO terms. +comment: This term should not be used for direct annotation, it is currently kept in GO as a placeholder for describing cell death phenotypes in uPHENO. When information is provided on a programmed cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'). Unintentional cell death, i.e. cell death caused by injury, ageing, or cell phenotypes observed as a result of a pathological mutation in an essential gene should NOT be annotated using GO terms. subset: gocheck_do_not_annotate synonym: "accidental cell death" RELATED [] synonym: "necrosis" RELATED [] @@ -3514,7 +3575,7 @@ subset: goslim_drosophila subset: goslim_generic subset: goslim_mouse subset: goslim_plant -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "caspase-independent apoptosis" RELATED [] synonym: "caspase-independent cell death" NARROW [] synonym: "non-apoptotic programmed cell death" NARROW [] @@ -3871,8 +3932,8 @@ subset: goslim_flybase_ribbon subset: goslim_generic subset: goslim_mouse subset: goslim_pombe +subset: goslim_prokaryote subset: goslim_yeast -subset: prokaryote_subset synonym: "biological signaling" EXACT [] synonym: "signaling process" EXACT [] synonym: "signalling" EXACT [] @@ -3899,7 +3960,7 @@ id: GO:0030030 name: cell projection organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon." [GOC:jl, GOC:mah, http://www.cogsci.princeton.edu/~wn/] -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "cell projection organisation" EXACT [] synonym: "cell projection organization and biogenesis" RELATED [GOC:mah] synonym: "cell surface structure organization and biogenesis" RELATED [GOC:mah] @@ -4085,7 +4146,7 @@ subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_pir -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "matrisome" NARROW [] synonym: "proteinaceous extracellular matrix" EXACT [] xref: NIF_Subcellular:nlx_subcell_20090513 @@ -4539,7 +4600,7 @@ subset: goslim_agr subset: goslim_flybase_ribbon subset: goslim_mouse subset: goslim_pir -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "cell process" BROAD [] synonym: "cellular process" BROAD [] synonym: "cellular projection" EXACT [] @@ -4574,12 +4635,14 @@ alt_id: GO:0034960 alt_id: GO:0043283 alt_id: GO:0044259 def: "The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:mah] +subset: gocheck_do_not_annotate subset: goslim_pir synonym: "biopolymer metabolic process" EXACT [GOC:mtg_chebi_dec09] synonym: "macromolecule metabolism" EXACT [] synonym: "multicellular organismal macromolecule metabolic process" NARROW [] synonym: "organismal macromolecule metabolism" EXACT [] is_a: GO:0008152 ! metabolic process +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI [Term] id: GO:0043226 @@ -4589,7 +4652,7 @@ def: "Organized structure of distinctive morphology and function. Includes the n subset: goslim_chembl subset: goslim_generic subset: goslim_pir -subset: prokaryote_subset +subset: goslim_prokaryote xref: NIF_Subcellular:sao1539965131 xref: Wikipedia:Organelle is_a: GO:0110165 ! cellular anatomical entity @@ -4751,9 +4814,11 @@ id: GO:0044238 name: primary metabolic process namespace: biological_process def: "The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism." [GOC:go_curators, http://www.metacyc.org] +subset: gocheck_do_not_annotate subset: goslim_pir synonym: "primary metabolism" EXACT [] is_a: GO:0008152 ! metabolic process +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI [Term] id: GO:0044249 @@ -5001,6 +5066,7 @@ id: GO:0048856 name: anatomical structure development namespace: biological_process def: "The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome." [GO_REF:0000021] +subset: gocheck_do_not_annotate subset: goslim_chembl subset: goslim_generic subset: goslim_plant @@ -5009,6 +5075,7 @@ is_a: GO:0032502 ! developmental process intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of UBERON:0000061 ! anatomical structure relationship: results_in_development_of UBERON:0000061 ! anatomical structure +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI [Term] id: GO:0048869 @@ -5026,7 +5093,7 @@ def: "Any process involved in the controlled self-propelled movement of a cell t subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "cell locomotion" EXACT [] synonym: "cell movement" RELATED [] synonym: "movement of a cell" EXACT [] @@ -5141,7 +5208,7 @@ subset: goslim_agr subset: goslim_flybase_ribbon subset: goslim_mouse subset: goslim_pir -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "physiological response to stimulus" EXACT [] is_a: GO:0008150 ! biological_process @@ -5469,7 +5536,7 @@ subset: goslim_generic subset: goslim_metagenomics subset: goslim_pir subset: goslim_pombe -subset: prokaryote_subset +subset: goslim_prokaryote synonym: "cellular macromolecule complex assembly" RELATED [] synonym: "cellular protein complex assembly" EXACT [] synonym: "cellular protein-containing complex assembly" RELATED [] @@ -5616,10 +5683,12 @@ id: GO:0071704 name: organic substance metabolic process namespace: biological_process def: "The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon." [GOC:mah] +subset: gocheck_do_not_annotate synonym: "organic molecular entity metabolic process" EXACT [] synonym: "organic molecular entity metabolism" EXACT [] synonym: "organic substance metabolism" EXACT [] is_a: GO:0008152 ! metabolic process +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI created_by: mah creation_date: 2010-03-08T03:32:18Z @@ -5659,7 +5728,7 @@ creation_date: 2010-09-10T01:39:16Z id: GO:0071944 name: cell periphery namespace: cellular_component -def: "The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures." [GOC:pdt] +def: "The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures." [GOC:pdt] subset: goslim_flybase_ribbon is_a: GO:0110165 ! cellular anatomical entity created_by: mah @@ -6017,6 +6086,7 @@ subset: goslim_pir is_a: GO:0005575 ! cellular_component is_a: UBERON:0000061 ! anatomical structure property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24200" xsd:anyURI +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI created_by: kmv creation_date: 2019-08-12T18:01:37Z @@ -6542,30 +6612,6 @@ subset: attribute_slim synonym: "relational shape quality" EXACT [] is_a: PATO:0000051 ! morphology -[Term] -id: PATO:0000068 -name: qualitative -namespace: quality -comment: TODO: define this or obsolete it and move children somewhere else. -is_a: PATO:0000001 ! quality - -[Term] -id: PATO:0000069 -name: deviation (from_normal) -namespace: quality -def: "A quality inhering in a bearer by virtue of the whether the bearer differs from normal or average." [PATOC:GVG] -subset: attribute_slim -is_a: PATO:0000068 ! qualitative - -[Term] -id: PATO:0000117 -name: size -namespace: quality -def: "A morphology quality inhering in a bearer by virtue of the bearer's physical magnitude." [WordNet:WordNet] -subset: attribute_slim -subset: scalar_slim -is_a: PATO:0000051 ! morphology - [Term] id: PATO:0000141 name: structure @@ -6602,36 +6648,6 @@ synonym: "round" RELATED [] synonym: "rounded" RELATED [] is_a: PATO:0000947 ! elliptic -[Term] -id: PATO:0000461 -name: normal -namespace: quality -def: "A quality inhering in a bearer by virtue of the bearer's exhibiting no deviation from normal or average." [PATOC:GVG] -subset: abnormal_slim -subset: mpath_slim -subset: value_slim -synonym: "average" RELATED [] -is_a: PATO:0000068 ! qualitative -property_value: RO:0002604 PATO:0000460 - -[Term] -id: PATO:0000586 -name: increased size -namespace: quality -alt_id: PATO:0001202 -def: "A size quality which is relatively high." [PATOC:GVG] -subset: value_slim -synonym: "big" RELATED [] -synonym: "enlarged" RELATED [] -synonym: "expanded" RELATED [] -synonym: "great" RELATED [] -synonym: "large" RELATED [] -is_a: PATO:0000117 ! size -is_a: PATO:0002305 ! increased object quality -intersection_of: PATO:0000117 ! size -intersection_of: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal -property_value: RO:0002604 PATO:0000587 - [Term] id: PATO:0000947 name: elliptic @@ -6981,32 +6997,6 @@ is_a: PATO:0002078 ! hollow relationship: dc-contributor https://orcid.org/0000-0002-2061-091X creation_date: 2011-06-08T06:33:50Z -[Term] -id: PATO:0002300 -name: increased quality -namespace: quality -def: "A quality that has a value that is increased compared to normal or average." [PATOC:GVG] -is_a: PATO:0000069 ! deviation (from_normal) -intersection_of: PATO:0000001 ! quality -intersection_of: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal -relationship: dc-contributor https://orcid.org/0000-0002-2061-091X -relationship: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal -property_value: RO:0002604 PATO:0002301 -creation_date: 2011-06-16T06:39:43Z - -[Term] -id: PATO:0002305 -name: increased object quality -namespace: quality -def: "A quality of an object that has a value that is increased compared to normal or average." [PATOC:GVG] -is_a: PATO:0001241 ! physical object quality -is_a: PATO:0002300 ! increased quality -intersection_of: PATO:0001241 ! physical object quality -intersection_of: RO:0015007 PATO:0000461 ! increased in magnitude relative to normal -relationship: dc-contributor https://orcid.org/0000-0002-2061-091X -property_value: RO:0002604 PATO:0002303 -creation_date: 2011-06-16T06:54:01Z - [Term] id: PATO:0002309 name: fiber shaped @@ -7088,6 +7078,16 @@ def: "A quality inhering in a bearer by virtue of the extent to which the bearer subset: attribute_slim is_a: PATO:0000141 ! structure +[Term] +id: PATO:0040072 +name: high nuclear/cytoplasmic ratio +namespace: quality +def: "A quality inhering in a cell by virtue of the cell having a high nuclear/cytoplasmic ratio." [http://lymerick.net/blood-cells.pdf, Wikipedia:NC_ratio&oldid=931936284] +comment: A high nuclear/cytolasmic ratio is 70% or higher. +synonym: "high N:C ratio" EXACT [] +is_a: PATO:0001396 ! cellular quality +created_by: http://orcid.org/0000-0001-5208-3432 + [Term] id: PATO:0070044 name: anatomical structure quality @@ -7594,7 +7594,7 @@ xref: EFO:0000799 xref: EHDAA2:0003193 xref: EMAPA:37283 {source="MA:th"} xref: EV:0100155 -xref: FBbt:00007000 +xref: FBbt:00007000 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: HAO:0000144 xref: MAT:0000023 xref: MESH:D005121 @@ -7728,7 +7728,7 @@ synonym: "ducts" RELATED OMO:0003004 [XAO:0004000] synonym: "exocrine duct" NARROW [] synonym: "exocrine gland duct" NARROW [] xref: AAO:0011123 -xref: FBbt:00100314 +xref: FBbt:00100314 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:30320 xref: galen:Duct xref: NCIT:C12948 @@ -7779,7 +7779,7 @@ xref: BILA:0000003 xref: CARO:0000003 xref: EHDAA2:0003003 xref: EMAPA:0 -xref: FBbt:00007001 +xref: FBbt:00007001 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:305751 xref: FMA:67135 xref: GAID:781 @@ -7950,7 +7950,7 @@ subset: vertebrate_core synonym: "glomerular capillary tuft" RELATED [ZFA:0001288] synonym: "glomerular tuft" RELATED INCONSISTENT [] synonym: "glomerulus" BROAD [] -synonym: "glomerulus renis" RELATED LATIN [Wikipedia:Glomerulus] +synonym: "glomerulus renis" RELATED OMO:0003011 [Wikipedia:Glomerulus] synonym: "Malphigian glomerulus" RELATED MISSPELLING [BTO:0000530] synonym: "Malpighian glomerulus" RELATED [http://medical-dictionary.thefreedictionary.com/malpighian+glomerulus] synonym: "Malpighian tuft" RELATED [http://medical-dictionary.thefreedictionary.com/malpighian+glomerulus] @@ -8092,7 +8092,7 @@ name: mesonephric tubule namespace: uberon def: "A mesonephric tubule is an epithelial tube that is part of the mesonephros[GO]. Genital ridge that is next to the mesonephros[WP]." [Wikipedia:Mesonephric_tubules] synonym: "renal tubules" RELATED OMO:0003004 [VHOG:0000500] -synonym: "tubuli mesonephrici" RELATED LATIN [Wikipedia:Mesonephric_tubules] +synonym: "tubuli mesonephrici" RELATED OMO:0003011 [Wikipedia:Mesonephric_tubules] xref: AAO:0010389 xref: EHDAA2:0001134 xref: EMAPA:16747 @@ -8115,8 +8115,8 @@ namespace: uberon def: "An epithelial swelling on the Wolffian duct that elongates to invade the adjacent metanephric mesenchyme[MP]." [MP:0010979, PMID:19828308] subset: pheno_slim synonym: "diverticulum" RELATED [BTO:0001646] -synonym: "diverticulum metanephricum" RELATED LATIN [Wikipedia:Ureteric_bud] -synonym: "gemma ureterica" RELATED LATIN [Wikipedia:Ureteric_bud] +synonym: "diverticulum metanephricum" RELATED OMO:0003011 [Wikipedia:Ureteric_bud] +synonym: "gemma ureterica" RELATED OMO:0003011 [Wikipedia:Ureteric_bud] synonym: "metanephric bud" RELATED [BTO:0001646] synonym: "metanephric diverticulum" RELATED [Wikipedia:Metanephros#Metanephros] synonym: "ureteric ampulla" RELATED [] @@ -8234,13 +8234,13 @@ synonym: "fertilized egg stage" RELATED [] synonym: "one cell stage" EXACT [] synonym: "one-cell stage" RELATED [VHOG:0000745] synonym: "zygote" RELATED [VHOG:0000745] -synonym: "zygotum" RELATED LATIN [Wikipedia:Zygote] +synonym: "zygotum" RELATED OMO:0003011 [Wikipedia:Zygote] xref: BilaDO:0000005 xref: BILS:0000106 xref: EFO:0001322 xref: EHDAA:27 xref: FBdv:00005288 -xref: IDOMAL:0000302 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: IDOMAL:0000302 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: NCIT:C12601 xref: PdumDv:0000100 xref: VHOG:0000745 @@ -8482,7 +8482,7 @@ namespace: uberon def: "The ventral part of the cloaca remaining after septation of the rectum, which further develops into part of the bladder, part of the prostatic part of the male urethra and the urethra and vestibule in females." [ISBN:0-683-40008-8, MP:0010116] subset: pheno_slim synonym: "fetal UGS" EXACT [PMID:18977204] -synonym: "sinus urogenitalis" EXACT LATIN [] +synonym: "sinus urogenitalis" EXACT OMO:0003011 [] synonym: "UGS" EXACT [MP:0010116] synonym: "urogenital sinus" BROAD [MP:0010116] xref: EHDAA2:0004060 @@ -8515,13 +8515,13 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "adult mouth" NARROW [] -synonym: "cavital oralis" RELATED LATIN [Wikipedia:Mouth] +synonym: "cavital oralis" RELATED OMO:0003011 [Wikipedia:Mouth] synonym: "cavitas oris" RELATED [BTO:0001090] synonym: "cavum oris" RELATED [BTO:0001090] synonym: "mouth cavity" RELATED [BTO:0001090] synonym: "oral region" RELATED [EHDAA2:0001326] synonym: "oral vestibule" RELATED [BTO:0001090] -synonym: "regio oralis" EXACT LATIN [BTO:0004698, FMA:49184, FMA:TA] +synonym: "regio oralis" EXACT OMO:0003011 [BTO:0004698, FMA:49184, FMA:TA] synonym: "rima oris" RELATED [BTO:0001090] synonym: "stoma" RELATED [] synonym: "stomatodaeum" RELATED [VHOG:0000812] @@ -8536,7 +8536,7 @@ xref: EFO:0000825 xref: EHDAA2:0001326 xref: EHDAA:542 xref: EMAPA:16262 -xref: FBbt:00003126 +xref: FBbt:00003126 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:49184 xref: GAID:75 xref: galen:Mouth @@ -8686,7 +8686,8 @@ id: UBERON:0000353 name: parenchyma namespace: uberon def: "Functional part of an organ in the body. This is in contrast to the stroma, which refers to the structural tissue of organs, being exactly, connective tissues." [Wikipedia:Parenchyma] -xref: BTO:0001539 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: BTO:0000999 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} +xref: BTO:0001539 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: EHDAA:3015 xref: EHDAA:3905 xref: EHDAA:3999 @@ -8721,9 +8722,9 @@ subset: human_reference_atlas subset: pheno_slim synonym: "kidney medulla" EXACT [OBOL:automatic] synonym: "medulla of kidney" EXACT [OBOL:automatic] -synonym: "medulla renalis" EXACT LATIN [FMA:74268, FMA:TA] +synonym: "medulla renalis" EXACT OMO:0003011 [FMA:74268, FMA:TA] synonym: "medullary pyramids" RELATED OMO:0003004 [FMA:74268] -synonym: "pyramides renales" EXACT LATIN [FMA:74268, FMA:TA] +synonym: "pyramides renales" EXACT OMO:0003011 [FMA:74268, FMA:TA] synonym: "renal marrow" RELATED [BTO:0001167] synonym: "renal medullae" EXACT OMO:0003004 [FMA:86327] synonym: "renal medullae set" EXACT OMO:0003004 [FMA:86327] @@ -8815,7 +8816,7 @@ xref: CALOHA:TS-2101 xref: CARO:0000004 xref: EHDAA2:0003004 xref: EMAPA:35178 -xref: FBbt:00007019 +xref: FBbt:00007019 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:9669 xref: galen:BodySubstance xref: HAO:0000004 @@ -8850,7 +8851,7 @@ xref: AEO:0000005 xref: BILA:0000005 xref: CARO:0000005 xref: EHDAA2:0003005 -xref: FBbt:00007017 +xref: FBbt:00007017 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:5897 xref: HAO:0000005 xref: NCIT:C94478 @@ -8878,7 +8879,7 @@ xref: AEO:0000006 xref: BILA:0000006 xref: CARO:0000006 xref: EHDAA2:0003006 -xref: FBbt:00007016 +xref: FBbt:00007016 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:67165 xref: HAO:0000006 xref: TAO:0001836 @@ -8904,7 +8905,7 @@ xref: AEO:0000007 xref: BILA:0000007 xref: CARO:0000007 xref: EHDAA2:0003007 -xref: FBbt:00007015 +xref: FBbt:00007015 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:67112 xref: HAO:0000007 xref: TAO:0001835 @@ -8942,11 +8943,11 @@ xref: EHDAA2:0003011 xref: EHDAA:392 xref: EMAPA:16103 xref: EV:0100000 -xref: FBbt:00004856 +xref: FBbt:00004856 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:7149 xref: galen:AnatomicalSystem xref: HAO:0000011 -xref: IDOMAL:0002460 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: IDOMAL:0002460 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: MA:0000003 xref: NCIT:C12919 xref: SCTID:278195005 @@ -8997,7 +8998,7 @@ xref: EHDAA2:0003191 xref: EHDAA:1 xref: EMAPA:25765 xref: EV:0100016 -xref: FBbt:00000001 +xref: FBbt:00000001 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:256135 xref: galen:Organism xref: HAO:0000012 @@ -9063,7 +9064,7 @@ xref: CARO:0000032 xref: EFO:0000808 xref: EHDAA2:0003032 xref: EMAPA:36031 -xref: FBbt:00007009 +xref: FBbt:00007009 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:7153 xref: galen:BodyPart xref: HAO:0000032 @@ -9099,7 +9100,7 @@ xref: AEO:0000040 xref: BILA:0000040 xref: CARO:0000040 xref: EHDAA2:0003040 -xref: FBbt:00007013 +xref: FBbt:00007013 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:63863 xref: HAO:0000040 xref: TAO:0000382 @@ -9119,8 +9120,7 @@ namespace: uberon def: "Anatomical group whose component anatomical structures lie in close proximity to each other." [FBbt:00007277] subset: common_anatomy subset: upper_level -xref: FBbt:00007277 -xref: IDOMAL:0002461 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: FBbt:00007277 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: VHOG:0001737 is_a: UBERON:0034923 ! disconnected anatomical group relationship: present_in_taxon NCBITaxon:33090 @@ -9147,7 +9147,7 @@ xref: CALOHA:TS-2090 xref: CARO:0000043 xref: EHDAA2:0003043 xref: EMAPA:35868 -xref: FBbt:00007003 +xref: FBbt:00007003 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:9637 xref: galen:Tissue xref: HAO:0000043 @@ -9182,7 +9182,7 @@ xref: AEO:0000055 xref: BILA:0000055 xref: CARO:0000055 xref: EHDAA2:0003055 -xref: FBbt:00007010 +xref: FBbt:00007010 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: HAO:0000055 xref: TAO:0001488 xref: TGMA:0001847 @@ -9215,7 +9215,7 @@ xref: CALOHA:TS-0288 xref: CARO:0000066 xref: EHDAA2:0003066 xref: EMAPA:32738 -xref: FBbt:00007005 +xref: FBbt:00007005 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:9639 xref: GAID:402 xref: HAO:0000066 @@ -9258,7 +9258,7 @@ xref: AEO:0000068 xref: BILA:0000068 xref: CARO:0000068 xref: EHDAA2_RETIRED:0003068 -xref: FBbt:00007027 +xref: FBbt:00007027 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:45567 xref: HAO:0000068 xref: NCIT:C33552 @@ -9437,11 +9437,11 @@ xref: EHDAA2:0000002 xref: EHDAA2_RETIRED:0003236 xref: EHDAA:38 xref: EMAPA:16039 -xref: FBbt:00000052 +xref: FBbt:00000052 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:69068 xref: GAID:963 xref: http://neurolex.org/wiki/Category\:Embryonic_organism -xref: IDOMAL:0000646 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: IDOMAL:0000646 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: MAT:0000226 xref: MESH:D004622 xref: MIAA:0000019 @@ -9481,7 +9481,7 @@ xref: AAO:0000480 xref: BILA:0000035 xref: BTO:0000556 xref: EMAPA:36033 -xref: FBbt:00000110 +xref: FBbt:00000110 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:69069 xref: GAID:1303 xref: MESH:D005855 @@ -9516,7 +9516,7 @@ xref: EFO:0000414 xref: EHDAA2:0000428 xref: EMAPA:16069 xref: EV:0100003 -xref: FBbt:00000111 +xref: FBbt:00000111 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:69070 xref: GAID:1304 xref: MAT:0000155 @@ -9557,7 +9557,7 @@ xref: EFO:0002545 xref: EHDAA2:0000436 xref: EMAPA:16062 xref: EV:0100005 -xref: FBbt:00000125 +xref: FBbt:00000125 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:69071 xref: GAID:1305 xref: MAT:0000175 @@ -9603,7 +9603,7 @@ xref: EHDAA:160 xref: EHDAA:183 xref: EMAPA:16083 xref: EV:0100006 -xref: FBbt:00000126 +xref: FBbt:00000126 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:69072 xref: GAID:522 xref: MAT:0000174 @@ -9647,7 +9647,7 @@ synonym: "stomodeal-hypophyseal primordium" BROAD [XAO:0000269] xref: BTO:0004224 xref: EHDAA2:0001929 xref: EMAPA:16263 -xref: FBbt:00000439 +xref: FBbt:00000439 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:295846 xref: NCIT:C34306 xref: TAO:0001290 @@ -9681,7 +9681,7 @@ synonym: "proctodaeum" EXACT [] xref: AAO:0011087 xref: EHDAA2:0000121 xref: EMAPA:25038 -xref: FBbt:00000123 +xref: FBbt:00000123 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: NCIT:C34278 xref: TAO:0000066 xref: UMLS:C0231054 {source="ncithesaurus:Proctodeum"} @@ -9847,6 +9847,7 @@ namespace: uberon def: "Anatomical system that has as its parts the organs concerned with reproduction." [Wikipedia:Reproductive_system] subset: efo_slim subset: functional_classification +subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core @@ -9858,7 +9859,7 @@ synonym: "Geschlechtsorgan" RELATED [BTO:0000081] synonym: "organa genitalia" RELATED [BTO:0000081] synonym: "reproductive tissue" RELATED [BTO:0000081] synonym: "reproductive tract" RELATED [] -synonym: "systemata genitalia" RELATED LATIN [Wikipedia:Reproductive_system] +synonym: "systemata genitalia" RELATED OMO:0003011 [Wikipedia:Reproductive_system] xref: AAO:0010258 xref: BILA:0000103 xref: BTO:0000081 @@ -9868,12 +9869,13 @@ xref: EHDAA2:0001603 xref: EHDAA:5923 xref: EMAPA:17381 xref: EV:0100100 -xref: FBbt:00004857 +xref: FBbt:00004857 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:7160 xref: GAID:363 xref: HAO:0000374 xref: HAO:0000895 xref: MA:0000326 +xref: MESH:D005835 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} xref: MIAA:0000305 xref: NCIT:C12841 xref: SCTID:278875001 @@ -9897,6 +9899,7 @@ disjoint_from: UBERON:8450002 ! excretory system relationship: capable_of_part_of GO:0000003 ! reproduction relationship: existence_ends_during UBERON:0000066 ! fully formed stage relationship: has_part UBERON:0000991 ! gonad +relationship: present_in_taxon NCBITaxon:9606 property_value: dcterms-date "2022-06-10T18:22:34Z" xsd:dateTime property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/5/52/Penis.svg" xsd:anyURI property_value: editor_note "consider splitting genitalia from reproductive system" xsd:string @@ -9921,7 +9924,7 @@ xref: BILA:0000123 xref: BSA:0000079 xref: BTO:0000534 xref: EMAPA:17383 -xref: FBbt:00004858 +xref: FBbt:00004858 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:18250 xref: GAID:368 xref: HAO:0000379 @@ -9968,7 +9971,7 @@ xref: BTO:0000058 xref: CALOHA:TS-1293 xref: EFO:0000793 xref: EV:0100056 -xref: FBbt:00005055 +xref: FBbt:00005055 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:7152 xref: GAID:278 xref: galen:DigestiveSystem @@ -10028,7 +10031,7 @@ xref: EHDAA2:0001601 xref: EHDAA:5901 xref: EMAPA:17366 xref: EV:0100095 -xref: FBbt:00005056 +xref: FBbt:00005056 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:7159 xref: GAID:391 xref: galen:UrinaryTract @@ -10067,9 +10070,10 @@ namespace: uberon def: "Organ system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis[WP]." [Wikipedia:Circulatory_system] subset: human_reference_atlas subset: uberon_slim -synonym: "systema cardiovasculare" RELATED LATIN [Wikipedia:Circulatory_system] +synonym: "systema cardiovasculare" RELATED OMO:0003011 [Wikipedia:Circulatory_system] xref: AAO:0000959 xref: CALOHA:TS-2103 +xref: MESH:D002319 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} xref: VHOG:0001248 xref: Wikipedia:Circulatory_system is_a: UBERON:0000467 ! anatomical system @@ -10106,7 +10110,7 @@ synonym: "muscles" RELATED [] synonym: "muscles set" EXACT [] synonym: "musculature" EXACT [] synonym: "musculature system" RELATED [] -synonym: "musculi" EXACT LATIN [FMA:32558, FMA:TA] +synonym: "musculi" EXACT OMO:0003011 [FMA:32558, FMA:TA] synonym: "set of muscles" EXACT [FMA:32558] synonym: "set of skeletal muscles" EXACT [MA:0000165] xref: AAO:0011066 @@ -10137,12 +10141,13 @@ namespace: uberon def: "The nervous system is an organ system containing predominantly neuron and glial cells. In bilaterally symmetrical organism, it is arranged in a network of tree-like structures connected to a central body. The main functions of the nervous system are to regulate and control body functions, and to receive sensory input, process this information, and generate behavior [CUMBO]." [BIRNLEX:844, ISBN:0-14-051288-8, ISBN:3110148986, NLM:nervous+system, WB:rynl, Wikipedia:Nervous_system, ZFIN:curator] subset: cumbo subset: efo_slim +subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "nerve net" NARROW [Wikipedia:Nerve_net] synonym: "neurological system" EXACT [GO:0050877] -synonym: "systema nervosum" RELATED LATIN [Wikipedia:Nervous_system] +synonym: "systema nervosum" RELATED OMO:0003011 [Wikipedia:Nervous_system] xref: AAO:0000324 xref: BILA:0000079 xref: BIRNLEX:844 @@ -10153,7 +10158,7 @@ xref: EHDAA2:0001246 xref: EHDAA:826 xref: EMAPA:16469 xref: EV:0100162 -xref: FBbt:00005093 +xref: FBbt:00005093 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:7157 xref: GAID:466 xref: MA:0000016 @@ -10182,6 +10187,7 @@ relationship: has_part CL:0000540 ! neuron relationship: immediate_transformation_of UBERON:0016880 {source="Bgee:AN"} ! future nervous system relationship: never_in_taxon NCBITaxon:6040 relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa +relationship: present_in_taxon NCBITaxon:9606 property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/b/b2/TE-Nervous_system_diagram.svg" xsd:anyURI property_value: depiction "http://upload.wikimedia.org/wikipedia/commons/b/ba/Nervous_system_diagram.png" xsd:anyURI property_value: UBPROP:0000001 "A regulatory system of the body that consists of neurons and neuroglial cells. The nervous system is divided into two parts, the central nervous system (CNS) and the peripheral nervous system (PNS). (Source: BioGlossary, www.Biology-Text.com)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000396", ontology="TAO", source="ZFIN:curator"} @@ -10197,13 +10203,14 @@ namespace: uberon def: "The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the neural tube derivatives: the brain and spinal cord. In invertebrates it includes central ganglia plus nerve cord." [GO:0021551, http://www.frontiersinzoology.com/content/7/1/29, https://sourceforge.net/p/geneontology/ontology-requests/11422/] subset: cumbo subset: efo_slim +subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "cerebrospinal axis" NARROW [FMA:55675] synonym: "CNS" EXACT OMO:0003000 [] synonym: "neuraxis" RELATED [FMA:55675] -synonym: "systema nervosum centrale" EXACT LATIN [FMA:55675, FMA:TA] +synonym: "systema nervosum centrale" EXACT OMO:0003011 [FMA:55675, FMA:TA] xref: AAO:0000090 xref: BAMS:CNS xref: BILA:0000080 @@ -10216,7 +10223,7 @@ xref: EHDAA:828 xref: EMAPA:16470 xref: EMAPA:16754 xref: EV:0100163 -xref: FBbt:00005094 +xref: FBbt:00005094 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:55675 xref: GAID:570 xref: MA:0000167 @@ -10237,6 +10244,7 @@ relationship: immediate_transformation_of UBERON:0016879 {source="Bgee:AN"} ! fu relationship: never_in_taxon NCBITaxon:147099 {source="Wikipedia:Acoelomorpha"} relationship: only_in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of UBERON:0001016 ! nervous system +relationship: present_in_taxon NCBITaxon:9606 property_value: UBPROP:0000001 "Part of the nervous system which includes the brain and spinal cord.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000090", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000001 "The brain and spinal cord. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000012", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "The central nervous system (CNS) is the part of the nervous system which includes the brain, spinal cord, and nerve cell layer of the retina (CUMBO)." xsd:string {source="BIRNLEX:1099"} @@ -10250,15 +10258,15 @@ def: "Anterior subdivision of a digestive tract." [http://orcid.org/0000-0002-66 subset: developmental_classification subset: pheno_slim subset: uberon_slim -synonym: "praeenteron" RELATED LATIN [Wikipedia:Foregut] -synonym: "proenteron" RELATED LATIN [Wikipedia:Foregut] +synonym: "praeenteron" RELATED OMO:0003011 [Wikipedia:Foregut] +synonym: "proenteron" RELATED OMO:0003011 [Wikipedia:Foregut] xref: AAO:0011042 xref: BILA:0000085 xref: BTO:0000507 xref: EHDAA2:0000557 xref: EHDAA:520 xref: EMAPA:16548 -xref: FBbt:00005379 +xref: FBbt:00005379 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:45616 xref: MA:0001526 xref: NCIT:C34180 @@ -10283,14 +10291,14 @@ subset: developmental_classification subset: efo_slim subset: pheno_slim subset: uberon_slim -synonym: "mesenteron" RELATED LATIN [Wikipedia:Midgut] +synonym: "mesenteron" RELATED OMO:0003011 [Wikipedia:Midgut] xref: BILA:0000086 xref: BTO:0000863 xref: EFO:0001950 xref: EHDAA2:0001185 xref: EHDAA:983 xref: EMAPA:16255 -xref: FBbt:00005383 +xref: FBbt:00005383 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:45617 xref: MA:0001564 xref: NCIT:C34210 @@ -10316,14 +10324,14 @@ def: "The caudalmost subdivision of a digestive tract." [http://orcid.org/0000-0 subset: developmental_classification subset: pheno_slim subset: uberon_slim -synonym: "metenteron" RELATED LATIN [Wikipedia:Hindgut] +synonym: "metenteron" RELATED OMO:0003011 [Wikipedia:Hindgut] xref: AAO:0011052 xref: BILA:0000087 xref: BTO:0000510 xref: EHDAA2:0000779 xref: EHDAA:975 xref: EMAPA:16715 -xref: FBbt:00005384 +xref: FBbt:00005384 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:45618 xref: MA:0001527 xref: NCIT:C34188 @@ -10359,7 +10367,7 @@ xref: AEO:0000171 xref: BTO:0001886 xref: EFO:0001652 xref: EHDAA2:0003171 -xref: FBbt:00005495 +xref: FBbt:00005495 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:86589 xref: MAT:0000482 xref: NCIT:C34275 @@ -10379,7 +10387,7 @@ subset: uberon_slim subset: vertebrate_core synonym: "neural primordium" RELATED [] synonym: "presumptive central nervous system" RELATED [] -synonym: "tubus neuralis" RELATED LATIN [Wikipedia:Neural_tube] +synonym: "tubus neuralis" RELATED OMO:0003011 [Wikipedia:Neural_tube] xref: AAO:0010617 xref: BTO:0001057 xref: CALOHA:TS-2371 @@ -10391,7 +10399,7 @@ xref: EMAPA:16164 xref: EMAPA:16757 xref: FMA:293882 xref: MAT:0000069 -xref: MESH:D054259 +xref: MESH:D054259 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: MIAA:0000069 xref: NCIT:C34226 xref: neuronames:1365 @@ -10427,7 +10435,7 @@ xref: BILA:0000000 xref: BIRNLEX:6 xref: CARO:0000000 xref: EHDAA2:0002229 -xref: FBbt:10000000 +xref: FBbt:10000000 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:62955 xref: HAO:0000000 xref: MA:0000001 @@ -10455,7 +10463,7 @@ synonym: "inferior caval vein" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "inferior vena cava" EXACT [Wikipedia:Venae_cavae] synonym: "postcava" RELATED [] synonym: "posterior vena cava" EXACT [Wikipedia:Venae_cavae] -synonym: "vena cava inferior" RELATED LATIN [BTO:0002682, Wikipedia:Inferior_vena_cava] +synonym: "vena cava inferior" RELATED OMO:0003011 [BTO:0002682, Wikipedia:Inferior_vena_cava] xref: AAO:0011083 xref: BTO:0002682 xref: EHDAA2:0000611 @@ -10521,7 +10529,7 @@ subset: uberon_slim synonym: "kidney vein" EXACT [OBOL:automatic] synonym: "renal venous tree" EXACT [] synonym: "vein of kidney" EXACT [OBOL:automatic] -synonym: "venae renales" RELATED LATIN [Wikipedia:Renal_vein] +synonym: "venae renales" RELATED OMO:0003011 [Wikipedia:Renal_vein] xref: BTO:0002681 xref: EHDAA2:0001602 xref: EHDAA:8722 @@ -10557,7 +10565,7 @@ subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "kidney pelvis" EXACT [] -synonym: "p. renallis" RELATED LATIN [Wikipedia:Renal_pelvis] +synonym: "p. renallis" RELATED OMO:0003011 [Wikipedia:Renal_pelvis] synonym: "pelvis of ureter" EXACT [] synonym: "pyelum" RELATED [MP:0004194] xref: CALOHA:TS-2230 @@ -10592,7 +10600,7 @@ def: "Outer cortical portion of the kidney, between the renal capsule and the re subset: human_reference_atlas subset: pheno_slim subset: uberon_slim -synonym: "cortex renalis" EXACT LATIN [FMA:15581, FMA:TA] +synonym: "cortex renalis" EXACT OMO:0003011 [FMA:15581, FMA:TA] synonym: "kidney cortex" EXACT [] synonym: "renal cortex" EXACT [] xref: BTO:0001166 @@ -10630,8 +10638,8 @@ subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "corpusculum renale" EXACT LATIN [] -synonym: "corpusculum renis" RELATED LATIN [Wikipedia:Renal_corpuscle] +synonym: "corpusculum renale" EXACT OMO:0003011 [] +synonym: "corpusculum renis" RELATED OMO:0003011 [Wikipedia:Renal_corpuscle] synonym: "cortical renal corpuscle" RELATED [MA:0000376] synonym: "kidney corpuscle" RELATED [Wikipedia:Renal_corpuscle] synonym: "Malphigian corpuscle" EXACT MISSPELLING [MA:0000376] @@ -10672,8 +10680,8 @@ subset: vertebrate_core synonym: "Bowman's capsule" EXACT [http://www.gudmap.org/About/Tutorial/DevMUS.html#DMK_Nephron] synonym: "Bowman's capsule" RELATED [TAO:0005254] synonym: "Bowmans capsule" EXACT [KUPO:0001001] -synonym: "capsula glomerularis" EXACT LATIN [] -synonym: "capsula glomeruli" RELATED LATIN [] +synonym: "capsula glomerularis" EXACT OMO:0003011 [] +synonym: "capsula glomeruli" RELATED OMO:0003011 [] synonym: "Malphigian capsule" RELATED MISSPELLING [BTO:0002297] synonym: "Malpighian capsule" RELATED [UBERON:cjm] synonym: "Mueller capsule" RELATED [BTO:0002297] @@ -10762,7 +10770,7 @@ synonym: "junctional tube" RELATED [Wikipedia:Connecting_tubule] synonym: "kidney collecting duct" EXACT [] synonym: "kidney collecting tubule" RELATED [] synonym: "renal collecting tubule" EXACT [FMA:15628] -synonym: "tubulus renalis arcuatus" EXACT LATIN [Wikipedia:Connecting_tubule] +synonym: "tubulus renalis arcuatus" EXACT OMO:0003011 [Wikipedia:Connecting_tubule] synonym: "tubulus renalis colligens" EXACT [] synonym: "ureteric tree" RELATED [EMAPA:28407] xref: BTO:0000761 @@ -10800,7 +10808,7 @@ synonym: "proctodeum" RELATED [] xref: BTO:0001680 xref: CALOHA:TS-2005 xref: EV:0100082 -xref: FBbt:00047153 +xref: FBbt:00047153 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:15711 xref: GAID:312 xref: galen:Anus @@ -10839,7 +10847,7 @@ subset: uberon_slim synonym: "bladder" BROAD [EHDAA2:0000174] synonym: "urocyst" RELATED [Wikipedia:Urinary_bladder] synonym: "vesica" RELATED [BTO:0001418] -synonym: "vesica urinaria" EXACT LATIN [Wikipedia:Urinary_bladder] +synonym: "vesica urinaria" EXACT OMO:0003011 [Wikipedia:Urinary_bladder] xref: AAO:0000623 xref: BTO:0001418 xref: CALOHA:TS-1090 @@ -10914,8 +10922,8 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "mature nephron" NARROW [EMAPA:28491] -synonym: "nephroneum" RELATED LATIN [Wikipedia:Nephron] -synonym: "tubulus renalis" RELATED LATIN [Wikipedia:Nephron] +synonym: "nephroneum" RELATED OMO:0003011 [Wikipedia:Nephron] +synonym: "tubulus renalis" RELATED OMO:0003011 [Wikipedia:Nephron] xref: BTO:0000924 xref: CALOHA:TS-1312 xref: EMAPA:28491 @@ -10957,8 +10965,8 @@ synonym: "PCT" RELATED [] synonym: "proximal convoluted renal tubule" EXACT [] synonym: "renal proximal convoluted tubule" RELATED [http://orcid.org/0000-0002-6601-2165] synonym: "tubulus contortus proximalis" EXACT [] -synonym: "tubulus contortus proximalis" RELATED LATIN [Wikipedia:Proximal_convoluted_tubule] -synonym: "tubulus convolutus proximalis" RELATED LATIN [] +synonym: "tubulus contortus proximalis" RELATED OMO:0003011 [Wikipedia:Proximal_convoluted_tubule] +synonym: "tubulus convolutus proximalis" RELATED OMO:0003011 [] xref: CALOHA:TS-2198 xref: EMAPA:28287 xref: EV:0100388 @@ -10988,7 +10996,7 @@ namespace: uberon def: "The section of the renal tubule in the kidney medulla with a hairpin bend; consists of a descending limb and an ascending limb, and is situated between the proximal convoluted tubule to the distal convoluted tubule; it functions to reabsorb water and ions from the urine." [MGI:csmith, MP:0004755] subset: pheno_slim subset: uberon_slim -synonym: "ansa nephroni" EXACT LATIN [Wikipedia:Loop_of_Henle] +synonym: "ansa nephroni" EXACT OMO:0003011 [Wikipedia:Loop_of_Henle] synonym: "Henle loop" EXACT [] synonym: "Henle's loop" EXACT [] xref: BTO:0004608 @@ -11088,8 +11096,8 @@ subset: uberon_slim synonym: "distal convoluted renal tubule" EXACT [] synonym: "second convoluted tubule" RELATED [] synonym: "tubulus contortus distalis" EXACT [] -synonym: "tubulus contortus distalis" RELATED LATIN [Wikipedia:Distal_convoluted_tubule] -synonym: "tubulus convolutus distalis" RELATED LATIN [] +synonym: "tubulus contortus distalis" RELATED OMO:0003011 [Wikipedia:Distal_convoluted_tubule] +synonym: "tubulus convolutus distalis" RELATED OMO:0003011 [] xref: EMAPA:28393 xref: EV:0100389 xref: FMA:17721 @@ -11121,8 +11129,8 @@ synonym: "outer zone of medulla of kidney" EXACT [] synonym: "outer zone of renal medulla" EXACT [] synonym: "renal outer medulla" EXACT [BTO:0001746] synonym: "set of outer region of renal pyramids" RELATED [FMA:17733] -synonym: "zona externa (medullaris renalis)" EXACT LATIN [FMA:17733, FMA:TA] -synonym: "zona externa medullae renalis" EXACT LATIN [FMA:17733, FMA:TA] +synonym: "zona externa (medullaris renalis)" EXACT OMO:0003011 [FMA:17733, FMA:TA] +synonym: "zona externa medullae renalis" EXACT OMO:0003011 [FMA:17733, FMA:TA] xref: BTO:0001746 xref: CALOHA:TS-0508 xref: EMAPA:28310 @@ -11251,10 +11259,11 @@ xref: BTO:0000545 xref: EHDAA2:0000726 xref: EHDAA:518 xref: EMAPA:16247 -xref: FBbt:00003125 +xref: FBbt:00003125 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:45615 xref: galen:AlimentaryTract xref: MA:0000917 +xref: MESH:D041981 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} xref: NCIT:C34082 xref: TAO:0000112 xref: TGMA:0001819 @@ -11281,6 +11290,7 @@ id: UBERON:0001556 name: lower urinary tract namespace: uberon def: "Subdivision of urinary system which consists of the urinary bladder and the urethra." [FMA:45659] +subset: human_reference_atlas subset: pheno_slim subset: uberon_slim xref: FMA:45659 @@ -11291,6 +11301,7 @@ is_a: UBERON:0011216 ! organ system subdivision relationship: has_part UBERON:0000057 ! urethra relationship: has_part UBERON:0001255 ! urinary bladder relationship: part_of UBERON:0001008 ! renal system +relationship: present_in_taxon NCBITaxon:9606 [Term] id: UBERON:0001630 @@ -11382,7 +11393,7 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "vascular element" RELATED [EMAPA:th] -synonym: "vena" RELATED LATIN [Wikipedia:Vein] +synonym: "vena" RELATED OMO:0003011 [Wikipedia:Vein] synonym: "venae" RELATED OMO:0003004 [VHOG:0001743] synonym: "venous subtree" BROAD [] synonym: "venous tree organ part" EXACT [] @@ -11487,7 +11498,7 @@ subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "venula" RELATED LATIN [Wikipedia:Venule] +synonym: "venula" RELATED OMO:0003011 [Wikipedia:Venule] xref: BTO:0002626 xref: EMAPA:35917 xref: FMA:63130 @@ -11516,7 +11527,7 @@ def: "The smallest division of the artery located between the muscular arteries subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "arteriola" RELATED LATIN [Wikipedia:Arteriole] +synonym: "arteriola" RELATED OMO:0003011 [Wikipedia:Arteriole] xref: AAO:0010253 xref: BTO:0001997 xref: EMAPA:35146 @@ -11553,7 +11564,7 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "region of vascular tree organ" EXACT [FMA:50722] -synonym: "vas sanguineum" RELATED LATIN [Wikipedia:Blood_vessel] +synonym: "vas sanguineum" RELATED OMO:0003011 [Wikipedia:Blood_vessel] synonym: "vascular element" BROAD [EMAPA:35993] synonym: "vascular tree organ region" EXACT [FMA:50722] xref: AAO:0011004 @@ -11711,7 +11722,7 @@ xref: BILA:0000034 xref: BTO:0000174 xref: CALOHA:TS-2110 xref: EFO:0000461 -xref: FBbt:00004208 +xref: FBbt:00004208 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:69067 xref: GAID:407 xref: MESH:D004628 @@ -11774,7 +11785,7 @@ def: "A cardiac atrium that is in the right side of the heart. It receives deoxy subset: human_reference_atlas subset: pheno_slim subset: uberon_slim -synonym: "atrium dextrum" RELATED LATIN [Wikipedia:Right_atrium] +synonym: "atrium dextrum" RELATED OMO:0003011 [Wikipedia:Right_atrium] synonym: "cardiac right atrium" EXACT [] synonym: "heart right atrium" EXACT [MA:0000075] synonym: "right atrium" EXACT [VHOG:0000328] @@ -11871,6 +11882,7 @@ xref: EMAPA:37721 {source="MA:th"} xref: FMA:71221 xref: MA:0002986 xref: MAT:0000148 +xref: MESH:D013131 {mapping:provider="https://github.com/biopragmatics/biomappings", mapping:justification="https://w3id.org/semapv/vocab/LexicalMatching"} xref: MIAA:0000148 xref: TAO:0000317 xref: VHOG:0000317 @@ -11900,7 +11912,7 @@ subset: vertebrate_core synonym: "appendicular skeleton" EXACT [] synonym: "entire appendicular skeleton" EXACT [https://github.com/obophenotype/uberon/issues/59] synonym: "paired fin skeleton" NARROW SENSU [] -synonym: "skeleton appendiculare" RELATED LATIN [Wikipedia:Appendicular_skeleton] +synonym: "skeleton appendiculare" RELATED OMO:0003011 [Wikipedia:Appendicular_skeleton] xref: AAO:0000747 xref: EFO:0000951 xref: EMAPA:32729 @@ -12035,7 +12047,7 @@ xref: EHDAA:1017 xref: EMAPA:16579 xref: FMA:72170 xref: MAT:0000117 -xref: MESH:D060910 +xref: MESH:D060910 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: MIAA:0000117 xref: NCIT:C34280 xref: SCTID:308804007 @@ -12135,7 +12147,7 @@ namespace: uberon def: "The part of the coelemic cavity lumen that is enclosed by the walls of the thorax." [UBERON:cjm, Wikipedia:Thoracic_cavity] subset: pheno_slim subset: uberon_slim -synonym: "cavitas thoracis" EXACT LATIN [Wikipedia:Thoracic_cavity] +synonym: "cavitas thoracis" EXACT OMO:0003011 [Wikipedia:Thoracic_cavity] synonym: "cavity of chest" EXACT [] synonym: "cavity of thorax" EXACT [] synonym: "chest cavity" EXACT [] @@ -12169,7 +12181,7 @@ def: "An anatomical structure which consists of juxtaglomerular cells, extraglom subset: human_reference_atlas subset: pheno_slim subset: uberon_slim -synonym: "complexus juxtaglomerularis" EXACT LATIN [] +synonym: "complexus juxtaglomerularis" EXACT OMO:0003011 [] synonym: "juxtaglomerular complex" EXACT [MP:0002829] xref: BTO:0005157 xref: EMAPA:30449 @@ -12256,7 +12268,7 @@ synonym: "ventral body cavity" NARROW [NCBITaxon:7742] xref: AEO:0000186 xref: BTO:0001707 xref: EHDAA2:0000267 -xref: FBbt:00005060 +xref: FBbt:00005060 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:85006 xref: galen:BodyCavity xref: NCIT:C25444 @@ -12282,7 +12294,7 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "embryonic notocord" EXACT [] -synonym: "notochorda" RELATED LATIN [Wikipedia:Notochord] +synonym: "notochorda" RELATED OMO:0003011 [Wikipedia:Notochord] synonym: "notocord" EXACT [ZFA:0000135] xref: AAO:0000327 xref: BTO:0001768 @@ -12341,7 +12353,7 @@ synonym: "epithelial somite" RELATED [https://github.com/obophenotype/uberon/wik synonym: "mesodermal cluster" BROAD [GO:0001756] synonym: "somites" RELATED OMO:0003004 [] synonym: "somitic mesoderm" RELATED [] -synonym: "somitus" RELATED LATIN [Wikipedia:Somite] +synonym: "somitus" RELATED OMO:0003011 [Wikipedia:Somite] xref: AAO:0010569 xref: AEO:0001015 xref: BTO:0001558 @@ -12407,7 +12419,7 @@ comment: Gene notes: Many factors and genes, such as Pax3 (Tremblay et al., 1995 subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "crista neuralis" RELATED LATIN [Wikipedia:Neural_crest] +synonym: "crista neuralis" RELATED OMO:0003011 [Wikipedia:Neural_crest] synonym: "NC" EXACT OMO:0003000 [XAO:0000048] synonym: "neural crest material" RELATED [VHOG:0000057] xref: AAO:0010578 @@ -12453,7 +12465,7 @@ namespace: uberon def: "Embryonic ectoderm that gives rise to nervous tissue." [Wikipedia:Neuroectoderm] subset: uberon_slim subset: vertebrate_core -synonym: "epithelium tubi neuralis; neuroectoderma" RELATED LATIN [Wikipedia:Neuroectoderm] +synonym: "epithelium tubi neuralis; neuroectoderma" RELATED OMO:0003011 [Wikipedia:Neuroectoderm] synonym: "neuaral ectoderm" RELATED [] synonym: "neural ectoderm" EXACT [] synonym: "neuroectoderm" EXACT [] @@ -12467,7 +12479,7 @@ xref: EHDAA:1498 xref: EHDAA:255 xref: EMAPA:16073 xref: EV:0100004 -xref: FBbt:00001057 +xref: FBbt:00001057 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:87657 xref: MAT:0000176 xref: MIAA:0000176 @@ -12670,7 +12682,7 @@ subset: vertebrate_core synonym: "blastocyst" RELATED [] synonym: "ectoblast" RELATED [MP:0003886] synonym: "epiblast" EXACT [VHOG:0000243] -synonym: "epiblastus" RELATED LATIN [Wikipedia:Epiblast] +synonym: "epiblastus" RELATED OMO:0003011 [Wikipedia:Epiblast] synonym: "primitive ectoderm" RELATED [VHOG:0000243] xref: BTO:0004593 xref: FMA:296704 @@ -12740,10 +12752,10 @@ def: "In mammals, the pronephric duct is the predecessor of the Wolffian duct[WP comment: The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the pronephric kidney[GOC:mtg_kidney_jan10, PMID:15647339, XAO:0000063, ZFA:0000150] subset: uberon_slim synonym: "archinephric duct" RELATED [VHOG:0000082] -synonym: "ductus pronephricus" RELATED LATIN [Wikipedia:Pronephric_duct] +synonym: "ductus pronephricus" RELATED OMO:0003011 [Wikipedia:Pronephric_duct] synonym: "pronephric ducts" RELATED OMO:0003004 [ZFA:0000150] xref: AAO:0011088 -xref: BTO:0005991 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: BTO:0005991 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: NCIT:C34279 xref: SCTID:361406002 xref: TAO:0000150 @@ -12809,7 +12821,7 @@ synonym: "IM" RELATED [] synonym: "intermediate mesenchyme" RELATED [https://github.com/obophenotype/uberon/wiki/The-neural-crest] synonym: "intermediate plate" RELATED [EMAPA:16178] synonym: "intermediate plate mesoderm" RELATED [https://orcid.org/0000-0002-6601-2165] -synonym: "mesenchyma intermedium" RELATED LATIN [Wikipedia:Intermediate_mesoderm] +synonym: "mesenchyma intermedium" RELATED OMO:0003011 [Wikipedia:Intermediate_mesoderm] xref: AAO:0010575 xref: EMAPA:16056 xref: EMAPA:16178 @@ -12864,12 +12876,12 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "archinephric duct" RELATED [VHOG:0000082, Wikipedia:Wolffian_duct] -synonym: "ductus mesonephricus; ductus Wolffi" RELATED LATIN [Wikipedia:Mesonephric_duct] +synonym: "ductus mesonephricus; ductus Wolffi" RELATED OMO:0003011 [Wikipedia:Mesonephric_duct] synonym: "Leydig's duct" RELATED [Wikipedia:Wolffian_duct] synonym: "renal duct" RELATED [] synonym: "Wolffian duct" EXACT [GOC:yaf, Wikipedia:Wolffian_duct, ZFA:0000546] xref: AAO:0000637 -xref: BTO:0005990 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: BTO:0005990 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: EHDAA2:0001243 xref: EHDAA:1590 xref: EMAPA:16577 @@ -12904,7 +12916,7 @@ def: "A region of embryonic ectodermal cells that lie directly above the notocho subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "lamina neuralis" RELATED LATIN [Wikipedia:Neural_plate] +synonym: "lamina neuralis" RELATED OMO:0003011 [Wikipedia:Neural_plate] synonym: "presumptive central nervous system" RELATED [] xref: AAO:0011072 xref: BTO:0001765 @@ -12914,7 +12926,7 @@ xref: EHDAA:346 xref: EHDAA:902 xref: EMAPA:35593 xref: FMA:293879 -xref: MESH:D054258 +xref: MESH:D054258 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: NCIT:C34225 xref: neuronames:1362 xref: RETIRED_EHDAA2:0001252 @@ -12942,7 +12954,7 @@ def: "The paraxial mesoderm is the mesoderm located bilaterally adjacent to the subset: efo_slim subset: uberon_slim subset: vertebrate_core -synonym: "mesoderma paraxiale" RELATED LATIN [Wikipedia:Paraxial_mesoderm] +synonym: "mesoderma paraxiale" RELATED OMO:0003011 [Wikipedia:Paraxial_mesoderm] synonym: "paraxial mesenchyme" EXACT [https://github.com/obophenotype/uberon/issues/30, https://github.com/obophenotype/uberon/wiki/The-neural-crest, ZFA:0000255] synonym: "somitic mesoderm" EXACT [ISBN:9780878932504] xref: AAO:0010568 @@ -12981,7 +12993,7 @@ synonym: "lateral mesoderm" EXACT [GO:0048368] synonym: "lateral plate" RELATED [] synonym: "lateral plate mesenchyme" RELATED [EHDAA2:0000919] synonym: "LPM" EXACT OMO:0003000 [ZFA:0000121] -synonym: "mesoderma laminae lateralis" RELATED LATIN [Wikipedia:Lateral_plate_mesoderm] +synonym: "mesoderma laminae lateralis" RELATED OMO:0003011 [Wikipedia:Lateral_plate_mesoderm] xref: AAO:0010574 xref: EHDAA2:0000919 xref: EHDAA:379 @@ -13042,10 +13054,10 @@ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "sclerotomes" EXACT OMO:0003004 [TAO:0001080] -synonym: "sclerotomus" RELATED LATIN [Wikipedia:Sclerotome] +synonym: "sclerotomus" RELATED OMO:0003011 [Wikipedia:Sclerotome] xref: AAO:0010571 xref: AEO:0000212 -xref: BTO:0006255 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: BTO:0006255 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: EHDAA2:0003439 xref: EMAPA:31159 xref: FMA:295652 @@ -13096,7 +13108,7 @@ def: "Portion of tissue composed of mesenchymal cells (motile cells that develop subset: pheno_slim subset: uberon_slim subset: vertebrate_core -synonym: "mesenchyma" RELATED LATIN [Wikipedia:Mesenchyme] +synonym: "mesenchyma" RELATED OMO:0003011 [Wikipedia:Mesenchyme] synonym: "mesenchymal tissue" EXACT [] synonym: "mesenchyme tissue" EXACT [] synonym: "portion of mesenchymal tissue" EXACT [] @@ -13398,7 +13410,7 @@ def: "Epithelial tubes transport gases, liquids and cells from one site to anoth synonym: "epithelial or endothelial tube" EXACT [] xref: AEO:0000114 xref: EHDAA2:0003114 -xref: FBbt:00007474 +xref: FBbt:00007474 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0000025 ! tube is_a: UBERON:0000483 ! epithelium intersection_of: UBERON:0000483 ! epithelium @@ -13471,7 +13483,7 @@ subset: human_reference_atlas subset: pheno_slim synonym: "collecting duct system" EXACT [Wikipedia:Collecting_duct_system] synonym: "kidney collecting duct system" EXACT [Wikipedia:Collecting_duct_system] -synonym: "tubulus renalis colligens" RELATED LATIN [Wikipedia:Collecting_duct_system] +synonym: "tubulus renalis colligens" RELATED OMO:0003011 [Wikipedia:Collecting_duct_system] xref: FMA:265239 xref: SCTID:279371005 xref: Wikipedia:Collecting_duct_system @@ -13772,6 +13784,7 @@ subset: pheno_slim synonym: "SSB" EXACT OMO:0003000 [] synonym: "stage II nephron" EXACT [http://www.gudmap.org/Organ_Summaries/Metanephros/Renal_vesicle.html] xref: EMAPA:27756 +xref: VO:0010896 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: ZFA:0005589 is_a: UBERON:0005423 ! developing anatomical structure relationship: develops_from UBERON:0004198 {source="GO"} ! comma-shaped body @@ -13794,7 +13807,7 @@ synonym: "medullary pyramid" RELATED [] synonym: "pyramid" BROAD [GO:0072056] synonym: "pyramid of Malphigi" RELATED MISSPELLING [ncithesaurus:Pyramid_of_Malpighi] synonym: "pyramid of Malpighi" RELATED [UBERON:cjm] -synonym: "pyramides renales" RELATED LATIN [Wikipedia:Renal_pyramids] +synonym: "pyramides renales" RELATED OMO:0003011 [Wikipedia:Renal_pyramids] synonym: "pyramis renalis" RELATED [BTO:0003926] synonym: "renal medullary region" RELATED [FMA:258870] synonym: "renal pyramid" EXACT [Wikipedia:Renal_pyramids] @@ -13831,7 +13844,7 @@ synonym: "outer stripe" EXACT [GO:0072058] synonym: "outer stripe of medulla of kidney" EXACT [FMA:76662] synonym: "outer stripe of outer medulla" EXACT [EMAPA:29663] synonym: "outer stripe of renal medulla" EXACT [FMA:76662] -synonym: "stria externa medullae renalis" EXACT LATIN [FMA:76662, FMA:TA] +synonym: "stria externa medullae renalis" EXACT OMO:0003011 [FMA:76662, FMA:TA] xref: EMAPA:29663 xref: FMA:76662 xref: MA:0002629 @@ -13973,7 +13986,7 @@ xref: EHDAA2:0001525 xref: EHDAA:185 xref: EMAPA:16072 xref: FMA:293110 -xref: MESH:D054240 +xref: MESH:D054240 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: NCIT:C28402 xref: SCTID:361438007 xref: UMLS:C0033153 {source="ncithesaurus:Primitive_Streak"} @@ -14108,6 +14121,7 @@ id: UBERON:0004638 name: blood vessel endothelium namespace: uberon def: "An endothelium that lines the blood vasculature. Other endothelia may line lymph vessels, the heart." [https://orcid.org/0000-0002-6601-2165] +subset: human_reference_atlas subset: pheno_slim subset: vertebrate_core xref: BTO:0000766 @@ -14122,6 +14136,7 @@ is_a: UBERON:0004852 ! cardiovascular system endothelium intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:0001981 ! blood vessel relationship: part_of UBERON:0001981 ! blood vessel +relationship: present_in_taxon NCBITaxon:9606 [Term] id: UBERON:0004639 @@ -14134,8 +14149,8 @@ subset: vertebrate_core synonym: "afferent arteriole" EXACT [MA:0002579] synonym: "afferent glomerular arteriole" EXACT [ZFA:0005307] synonym: "afferent glomerular arteriole of kidney" EXACT [FMA:77042] -synonym: "arteriola glomerularis afferens" RELATED LATIN [Wikipedia:Afferent_arterioles] -synonym: "arteriola glomerularis afferens renis" EXACT LATIN [FMA:77042, FMA:TA] +synonym: "arteriola glomerularis afferens" RELATED OMO:0003011 [Wikipedia:Afferent_arterioles] +synonym: "arteriola glomerularis afferens renis" EXACT OMO:0003011 [FMA:77042, FMA:TA] synonym: "kidney afferent arteriole" EXACT [MP:0011312] xref: EMAPA:28230 xref: EMAPA:28266 @@ -14185,8 +14200,8 @@ namespace: uberon def: "The branches of the arcuate arteries of the kidney that radiate outward throught the renal columns and supply the glomeruli[MP]. The first set of renal bloodvessels, the interlobular arteries (or cortical radiate arteries, or cortical radial arteries), are given off at right angles from the side of the arcuate arteries looking toward the cortical substance, and pass directly outward between the medullary rays to reach the fibrous tunic, where they end in the capillary network of this part. These vessels do not anastomose with each other, but form what are called end-arteries. In their outward course they give off lateral branches; these are the afferent vessels for the renal corpuscles; they enter the capsule, and end in the glomerulus. From each tuft the corresponding efferent vessel arises, and, having made its egress from the capsule near to the point where the afferent vessel enters, breaks up into a number of branches, which form a dense plexus within Bowman's capsule." [MP:0011316, Wikipedia:Interlobular_arteries] subset: human_reference_atlas subset: pheno_slim -synonym: "arteriae corticales radiatae" RELATED LATIN [Wikipedia:Interlobular_arteries] -synonym: "arteriae interlobulares renis" RELATED LATIN [Wikipedia:Interlobular_arteries] +synonym: "arteriae corticales radiatae" RELATED OMO:0003011 [Wikipedia:Interlobular_arteries] +synonym: "arteriae interlobulares renis" RELATED OMO:0003011 [Wikipedia:Interlobular_arteries] synonym: "cortical radial arteries" RELATED [Wikipedia:Interlobular_arteries] synonym: "interlobular" RELATED [Wikipedia:Interlobular_arteries] synonym: "interlobular renal artery" EXACT [FMA:70498] @@ -14223,7 +14238,7 @@ synonym: "trilaminar disk" RELATED [https://orcid.org/0000-0002-6601-2165] synonym: "trilaminar germ" RELATED [https://orcid.org/0000-0002-6601-2165] xref: BILA:0000060 xref: BTO:0001403 -xref: FBbt:00005317 +xref: FBbt:00005317 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:293108 xref: GAID:1302 xref: MESH:D005775 @@ -14393,7 +14408,7 @@ name: nephrogenic cord namespace: uberon def: "A portion of the urogenital ridge which is the source of much of the urinary system[WP]." [Wikipedia:Nephrogenic_cord] comment: part_of or develops_from urogenital ridge? -synonym: "chorda nephrogenica" RELATED LATIN [Wikipedia:Nephrogenic_cord] +synonym: "chorda nephrogenica" RELATED OMO:0003011 [Wikipedia:Nephrogenic_cord] xref: FMA:72168 xref: NCIT:C34219 xref: SCTID:361405003 @@ -14450,7 +14465,7 @@ namespace: uberon def: "Anatomical structure that connects two or more adjacent skeletal elements or hardened body parts." [http://orcid.org/0000-0002-6601-2165] subset: grouping_class synonym: "joint" NARROW [] -xref: FBbt:00005811 +xref: FBbt:00005811 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0034921 ! multi organ part structure relationship: part_of UBERON:0004770 ! articular system @@ -14466,7 +14481,7 @@ synonym: "gut section" RELATED [FBbt:00100315] synonym: "intestinal tract" RELATED [] synonym: "segment of intestinal tract" RELATED [] synonym: "subdivision of alimentary system" RELATED [FMA:71131] -xref: FBbt:00100315 +xref: FBbt:00100315 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:71131 is_a: UBERON:0013522 ! subdivision of tube intersection_of: UBERON:0013522 ! subdivision of tube @@ -14581,7 +14596,7 @@ property_value: IAO:0000232 "in some organisms such as drosophila, muscles can b id: UBERON:0005095 name: kidney rudiment namespace: uberon -def: "." [GO:0072003] +def: "Missing definition for term UBERON:0005095. Please replace it using linked reference." [GO:0072003] synonym: "kidney anlage" RELATED [GOC:mtg_kidney_jan10] is_a: UBERON:0002050 ! embryonic structure relationship: develops_from UBERON:0007687 {source="GO"} ! kidney field @@ -14624,7 +14639,7 @@ def: "The connecting tubule is a tubular segment of the nephron; it connects the subset: human_reference_atlas synonym: "connecting tubule" EXACT [MA:0002610] synonym: "kidney connecting tubule" EXACT [MA:0002610] -synonym: "tubulus renalis arcuatus" RELATED LATIN [Wikipedia:Connecting_tubule] +synonym: "tubulus renalis arcuatus" RELATED OMO:0003011 [Wikipedia:Connecting_tubule] xref: BTO:0004539 xref: EMAPA:27758 xref: EMAPA:27790 @@ -14910,7 +14925,7 @@ synonym: "developmental tissue" RELATED [MIAA:0000019] xref: AEO:0000125 xref: CALOHA:TS-2122 xref: EHDAA2:0003125 -xref: FBbt:00007006 +xref: FBbt:00007006 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:292313 xref: MIAA:0000019 is_a: UBERON:0000465 ! material anatomical entity @@ -14927,7 +14942,7 @@ def: "Multi-tissue structure that arises from the heart rudiment and will become subset: vertebrate_core synonym: "early primitive heart tube" NARROW [EMAPA:16208] synonym: "primitive heart tube" EXACT [EMAPA:16215] -xref: BTO:0006179 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: BTO:0006179 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: EHDAA2:0001512 xref: EHDAA:424 xref: EHDAA:436 @@ -15054,7 +15069,7 @@ namespace: uberon def: "An acellular membrane that is part of the epithelium, lies adjacent to the epithelial cells, and is the fusion of the the basal lamina and the reticular lamina." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Basement_membrane] synonym: "basement membrane" RELATED [FMA:63872] synonym: "basement membrane of connective tissue" EXACT [FMA:63872] -synonym: "membrana basalis" EXACT LATIN [Wikipedia:Basement_membrane] +synonym: "membrana basalis" EXACT OMO:0003011 [Wikipedia:Basement_membrane] xref: AAO:0010596 xref: FMA:63872 xref: GAID:915 @@ -15086,7 +15101,7 @@ xref: EMAPA:28251 xref: EMAPA:30965 xref: FMA:74274 xref: MA:0001659 -xref: MESH:D050533 +xref: MESH:D050533 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0001-9439-5346", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: NCIT:C32683 xref: SCTID:243897006 xref: TAO:0005285 @@ -15137,7 +15152,7 @@ def: "Subdivision of skeleton which consists of cranial skeleton, set of all ver subset: human_reference_atlas subset: pheno_slim subset: uberon_slim -synonym: "skeleton axiale" RELATED LATIN [Wikipedia:Axial_skeleton] +synonym: "skeleton axiale" RELATED OMO:0003011 [Wikipedia:Axial_skeleton] xref: AAO:0000963 xref: EMAPA:17214 xref: EMAPA:18043 @@ -15165,7 +15180,7 @@ def: "The membrane that covers the embryonic cloaca, formed by the union of proc subset: emapa_ehdaa2 subset: pheno_slim synonym: "embryonic cloacal membrane" EXACT [] -synonym: "membrana cloacalis" RELATED LATIN [Wikipedia:Cloacal_membrane] +synonym: "membrana cloacalis" RELATED OMO:0003011 [Wikipedia:Cloacal_membrane] xref: EHDAA2:0000257 xref: EHDAA:214 xref: EHDAA:2933 @@ -15424,7 +15439,7 @@ def: "The distalmost portion of the digestive tract, derived from the hindgut, a synonym: "rectal part of digestive tract" RELATED [] synonym: "rectum" NARROW [FBbt:00005756] synonym: "terminal section of digestive tract" RELATED [] -xref: FBbt:00005756 +xref: FBbt:00005756 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: WBbt:0005773 is_a: UBERON:0004921 ! subdivision of digestive tract relationship: continuous_with UBERON:0001245 ! anus @@ -15764,7 +15779,7 @@ synonym: "organ field" RELATED [] xref: AEO:0000170 xref: EFO:0001649 xref: EHDAA2:0003170 -xref: FBbt:00005426 +xref: FBbt:00005426 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: Wikipedia:Anlage_(biology) is_a: UBERON:0000479 {source="FBbt"} ! tissue is_a: UBERON:0005423 {source="AEO", source="FBbt"} ! developing anatomical structure @@ -15995,7 +16010,7 @@ def: "An artery that supplies a renal lobe." [http://orcid.org/0000-0002-6601-21 subset: human_reference_atlas subset: pheno_slim synonym: "arteriae interlobares renis" EXACT OMO:0003004 [FMA:TA] -synonym: "arteriae interlobares renis" RELATED LATIN [Wikipedia:Interlobar_arteries] +synonym: "arteriae interlobares renis" RELATED OMO:0003011 [Wikipedia:Interlobar_arteries] synonym: "interlobar arteries of kidney" RELATED [FMA:71637] synonym: "interlobar artery of kidney" EXACT [FMA:71637] synonym: "kidney interlobar artery" EXACT [] @@ -16019,7 +16034,7 @@ name: anatomical lobe namespace: uberon def: "A portion of an organ, such as the liver, lung, breast, or brain." [ncithesaurus:Lobe] subset: upper_level -synonym: "lobus" EXACT LATIN [FMA:45728, FMA:TA] +synonym: "lobus" EXACT OMO:0003011 [FMA:45728, FMA:TA] xref: FMA:45728 xref: NCIT:C13393 xref: UMLS:C0796494 @@ -16032,7 +16047,7 @@ namespace: uberon def: "The portion of a kidney consisting of a renal medullary pyramid and the renal cortex above it[MP]. It is composed of many renal lobules[WP]." [MP:0011381, Wikipedia:Renal_lobe] subset: pheno_slim synonym: "kidney lobe" EXACT [MP:0011381] -synonym: "lobi renales" RELATED LATIN [Wikipedia:Renal_lobe] +synonym: "lobi renales" RELATED OMO:0003011 [Wikipedia:Renal_lobe] synonym: "lobi renalis" EXACT OMO:0003004 [Wikipedia:Renal_lobe] synonym: "lobus renalis" EXACT [http://www.mondofacto.com/facts/dictionary?lobus+renalis] xref: FMA:17881 @@ -16057,7 +16072,7 @@ subset: common_anatomy subset: upper_level synonym: "multicellular structure" EXACT [FBbt:00100313] xref: CARO:0010000 -xref: FBbt:00100313 +xref: FBbt:00100313 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0000061 ! anatomical structure intersection_of: UBERON:0000061 ! anatomical structure intersection_of: has_quality PATO:0001993 ! multicellular @@ -16310,8 +16325,9 @@ name: organ system subdivision namespace: uberon def: "A subdivision of an anatomical system." [http://orcid.org/0000-0002-6601-2165] subset: common_anatomy +subset: human_reference_atlas subset: upper_level -xref: FBbt:00007330 +xref: FBbt:00007330 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} xref: FMA:67509 xref: SCTID:91690000 is_a: UBERON:0010000 {source="FBbt"} ! multicellular anatomical structure @@ -16319,6 +16335,7 @@ relationship: part_of UBERON:0000467 ! anatomical system relationship: present_in_taxon NCBITaxon:33090 relationship: present_in_taxon NCBITaxon:33208 ! Metazoa relationship: present_in_taxon NCBITaxon:4751 +relationship: present_in_taxon NCBITaxon:9606 [Term] id: UBERON:0011249 @@ -16467,7 +16484,7 @@ id: UBERON:0013241 name: embryonic urethral groove namespace: uberon def: "The precursor of the urethra." [http://orcid.org/0000-0002-6601-2165] -synonym: "sulcus urethralis primarius" EXACT LATIN [Wikipedia:Urethral_groove] +synonym: "sulcus urethralis primarius" EXACT OMO:0003011 [Wikipedia:Urethral_groove] synonym: "urethral groove" EXACT [] synonym: "urethral sulcus" EXACT [] xref: SCTID:361531004 @@ -16515,7 +16532,6 @@ id: UBERON:0013702 name: body proper namespace: uberon def: "The region of the organism associated with the visceral organs." [AEO:0000103] -subset: human_reference_atlas subset: non_informative synonym: "body" RELATED [AEO:0000103] synonym: "whole body" RELATED [BTO:0001489] @@ -16525,7 +16541,6 @@ xref: EMAPA:36031 xref: FMA:231424 is_a: UBERON:0000475 {source="AEO"} ! organism subdivision relationship: part_of UBERON:0013701 ! main body axis -relationship: present_in_taxon NCBITaxon:9606 property_value: UBPROP:0000001 "Cardinal body part, which consists of a maximal set of diverse subclasses of organ and organ part spatially associated with the vertebral column and ribcage. Examples: There is only one body proper[FMA:231424]." xsd:string {source="FMA:231424"} [Term] @@ -16536,7 +16551,7 @@ def: "A blood that is part of a vein." [OBOL:automatic] synonym: "blood in vein" EXACT [FMA:83067] synonym: "portion of venous blood" EXACT [FMA:83067] synonym: "venous blood" EXACT [FMA:83067] -xref: BTO:0006187 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: BTO:0006187 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} xref: FMA:83067 is_a: UBERON:0000178 ! blood intersection_of: UBERON:0000178 ! blood @@ -16717,7 +16732,7 @@ namespace: uberon def: "Material anatomical entity consisting of multiple anatomical structures that are not connected to each other." [CARO:0020000] subset: common_anatomy xref: CARO:0020000 -xref: FBbt:00007276 +xref: FBbt:00007276 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration"} is_a: UBERON:0000465 {source="CARO"} ! material anatomical entity relationship: composed_primarily_of UBERON:0000061 ! anatomical structure relationship: has_component UBERON:0000061 {minCardinality="2"} ! anatomical structure @@ -16829,11 +16844,13 @@ id: UBERON:0036295 name: renal pelvis/ureter namespace: uberon def: "The upper tract of the renal system. The renal pelvis is the large cavity in the middle of each kidney. Urine drains from each kidney through a long tube called the ureter, into the bladder, where it is stored until it is passed from the body through the urethra." [NCIT:C54419] +subset: human_reference_atlas synonym: "renal pelvis and ureter" EXACT [] synonym: "renal pelvis plus ureter" EXACT [] xref: NCIT:C54419 is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0011143 {source="NCIT"} ! upper urinary tract +relationship: present_in_taxon NCBITaxon:9606 [Term] id: UBERON:8410081 @@ -16854,7 +16871,7 @@ name: excretory system namespace: uberon def: "An anatomical system that eliminates waste products that arise as a result of metabolic activity." [GO:0007588] subset: human_reference_atlas -xref: BTO:0006338 {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0003-4423-4370"} +xref: BTO:0006338 {mapping:justification="https://w3id.org/semapv/vocab/ManualMappingCuration", author:id="https://orcid.org/0000-0003-4423-4370", mapping:provider="https://github.com/biopragmatics/biomappings"} is_a: UBERON:0000467 ! anatomical system intersection_of: UBERON:0000467 ! anatomical system intersection_of: capable_of GO:0046903 ! secretion @@ -17254,20 +17271,6 @@ property_value: seeAlso "https://github.com/obophenotype/uberon/wiki/Part-disjoi is_a: RO:0002323 ! mereotopologically related to expand_expression_to: "BFO_0000051 exactly 0 (BFO_0000050 some ?Y)" [] -[Typedef] -id: RO:0002203 -name: develops into -def: "inverse of develops from" [] -subset: RO:0002259 -property_value: IAO:0000114 IAO:0000125 -property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 -property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172 -property_value: IAO:0000117 https://orcid.org/0000-0003-1980-3228 -is_transitive: true -is_a: has_potential_to_develop_into ! has potential to develop into -is_a: RO:0002286 ! developmentally succeeded by -is_a: RO:0002388 ! has potential to directly develop into - [Typedef] id: RO:0002206 name: expressed in @@ -17288,7 +17291,7 @@ def: "inverse of directly develops from" [] subset: RO:0002259 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000118 "developmental precursor of" xsd:string -is_a: RO:0002203 ! develops into +is_a: develops_into ! develops into [Typedef] id: RO:0002222 @@ -17318,7 +17321,7 @@ def: "inverse of has developmental contribution from" [] subset: RO:0002259 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 -holds_over_chain: RO:0002203 part_of +holds_over_chain: develops_into part_of is_a: has_potential_to_developmentally_contribute_to ! has potential to developmentally contribute to is_a: RO:0002286 ! developmentally succeeded by @@ -18603,7 +18606,7 @@ range: BFO:0000004 ! independent continuant is_transitive: true is_a: has_developmental_contribution_from ! has developmental contribution from is_a: RO:0002258 ! developmentally preceded by -inverse_of: RO:0002203 ! develops into +inverse_of: develops_into ! develops into [Typedef] id: develops_from_part_of @@ -18630,6 +18633,22 @@ domain: UBERON:0001062 ! anatomical entity holds_over_chain: directly_develops_from located_in is_a: RO:0002258 ! developmentally preceded by +[Typedef] +id: develops_into +name: develops into +namespace: uberon +def: "inverse of develops from" [] +subset: RO:0002259 +xref: RO:0002203 +property_value: IAO:0000114 IAO:0000125 +property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 +property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172 +property_value: IAO:0000117 https://orcid.org/0000-0003-1980-3228 +is_transitive: true +is_a: has_potential_to_develop_into ! has potential to develop into +is_a: RO:0002286 ! developmentally succeeded by +is_a: RO:0002388 ! has potential to directly develop into + [Typedef] id: directly_develops_from name: directly develops from @@ -18965,7 +18984,7 @@ is_a: RO:0002479 ! has part that occurs in id: has_high_plasma_membrane_amount name: obsolete has_high_plasma_membrane_amount def: "OBSOLETE A relation between a cell and molecule or complex such that every instance of the cell has a high number of instances of that molecule expressed on the cell surface. For the formal definition, see Masci et al (PMID:19243617)." [PMID:19243617] -comment: Replaced with RO:0015015, see https://github.com/obophenotype/cell-ontology/issues/1481 +property_value: term_tracker_item https://github.com/obophenotype/cell-ontology/issues/1481 is_obsolete: true replaced_by: RO:0015015 @@ -18992,7 +19011,7 @@ inverse_of: input_of ! input of id: has_low_plasma_membrane_amount name: obsolete has_low_plasma_membrane_amount def: "OBSOLETE A relation between a cell and molecule or complex such that every instance of the cell has a low number of instances of that molecule expressed on the cell surface. For the formal definition, see Masci et al (PMID:19243617)." [PMID:19243617] -comment: Replaced with RO:0015016, see https://github.com/obophenotype/cell-ontology/issues/1481 +property_value: term_tracker_item https://github.com/obophenotype/cell-ontology/issues/1481 is_obsolete: true replaced_by: RO:0015016 @@ -20380,21 +20399,21 @@ is_a: develops_from ! develops from id: transitively_anteriorly_connected_to name: transitively anteriorly connected to namespace: uberon -def: "." [http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern] +property_value: seeAlso "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" xsd:anyURI is_transitive: true [Typedef] id: transitively_distally_connected_to name: transitively distally connected to namespace: uberon -def: "." [http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern] +property_value: seeAlso "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" xsd:anyURI is_transitive: true [Typedef] id: transitively_proximally_connected_to name: transitively proximally connected to namespace: uberon -def: "." [http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern] +property_value: seeAlso "http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern" xsd:anyURI is_transitive: true [Typedef] diff --git a/subsets/kidney_upper_slim.owl b/subsets/kidney_upper_slim.owl index a5d1fc86e..a3abeb5aa 100644 --- a/subsets/kidney_upper_slim.owl +++ b/subsets/kidney_upper_slim.owl @@ -18,6 +18,7 @@ xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#" xmlns:skos="http://www.w3.org/2004/02/skos/core#" xmlns:swrl="http://www.w3.org/2003/11/swrl#" + xmlns:sssom="https://w3id.org/sssom/" xmlns:swrla="http://swrl.stanford.edu/ontologies/3.3/swrla.owl#" xmlns:swrlb="http://www.w3.org/2003/11/swrlb#" xmlns:terms="http://purl.org/dc/terms/" @@ -29,8 +30,8 @@ xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#" xmlns:ncbitaxon="http://purl.obolibrary.org/obo/ncbitaxon#"> - - 2024-01-04 + + 2024-02-13 @@ -315,6 +316,14 @@ Annotations: IAO_0000424 "http://purl.obolibrary.org/obo/BFO_0000051 some ( + + + + + + + + @@ -337,6 +346,14 @@ Annotations: IAO_0000424 "http://purl.obolibrary.org/obo/BFO_0000051 some ( + + + + + + + + @@ -846,25 +863,25 @@ WHERE { - + - + - + - + - + - + @@ -1071,14 +1088,6 @@ WHERE { - - - - - - - - @@ -1103,14 +1112,6 @@ WHERE { - - - - - - - - @@ -1942,6 +1943,24 @@ WHERE { + + + + + + + + + + + + + + + + + + - - - - - - - - - - - - - - - - - - - - - A nucleus size quality which is relatively high compared to the amount of cytoplasm present in the same cell. - - 2009-12-23T10:53:24Z - increased nucleus size - - - - - A nucleus size quality which is relatively high compared to the amount of cytoplasm present in the same cell. - GOC:tfm - - - - @@ -12544,6 +12571,7 @@ For example, A and B may be gene products and binding of B by A positively regul An epithelial cell that is part of the nephron. FMA:70965 + epithelial cell of nephron @@ -12581,6 +12609,7 @@ For example, A and B may be gene products and binding of B by A positively regul KUPO:0001034 Bowmans capsule epithelial cell epithelial cell of Bowman's capsule + epithelial cell of glomerular capsule @@ -12621,6 +12650,7 @@ For example, A and B may be gene products and binding of B by A positively regul FMA:70982 KUPO:0001059 epithelial cell of renal collecting tubule + kidney collecting duct epithelial cell @@ -12678,6 +12708,7 @@ For example, A and B may be gene products and binding of B by A positively regul FMA:86785 KUPO:0001022 kidney tubule epithelial cell + This needs to be further defined as a juxtamedullary nephron. Will request the juxtamedullary nephron tubule class from UBERON. nephron tubule epithelial cell @@ -12713,6 +12744,7 @@ For example, A and B may be gene products and binding of B by A positively regul A cell that is part of a kidney. KUPO:0001010 + kidney cell @@ -12742,6 +12774,7 @@ For example, A and B may be gene products and binding of B by A positively regul A cell that is part of kidney interstitium. KUPO:0001013 + kidney interstitial cell @@ -12856,6 +12889,7 @@ For example, A and B may be gene products and binding of B by A positively regul KUPO:0001023 + kidney glomerular epithelial cell @@ -12978,6 +13012,7 @@ For example, A and B may be gene products and binding of B by A positively regul KUPO:0001024 + kidney cortex tubule cell @@ -13048,6 +13083,7 @@ For example, A and B may be gene products and binding of B by A positively regul KUPO:0001102 + kidney interstitial fibroblast @@ -13111,6 +13147,7 @@ For example, A and B may be gene products and binding of B by A positively regul KUPO:0001058 + kidney connecting tubule epithelial cell @@ -13147,6 +13184,7 @@ For example, A and B may be gene products and binding of B by A positively regul KUPO:0001056 + kidney distal convoluted tubule epithelial cell @@ -13257,6 +13295,7 @@ For example, A and B may be gene products and binding of B by A positively regul KUPO:0001030 + kidney capillary endothelial cell @@ -13319,6 +13358,7 @@ For example, A and B may be gene products and binding of B by A positively regul KUPO:0001047 + kidney loop of Henle epithelial cell @@ -13353,6 +13393,7 @@ For example, A and B may be gene products and binding of B by A positively regul KUPO:0001048 + kidney loop of Henle ascending limb epithelial cell @@ -13423,6 +13464,7 @@ For example, A and B may be gene products and binding of B by A positively regul A cell that is part of a collecting duct of renal tubule. KUPO:0001012 Wikipedia:Kidney_collecting_duct_cell + kidney collecting duct cell @@ -13447,6 +13489,7 @@ For example, A and B may be gene products and binding of B by A positively regul A pericyte cell located in the kidney interstitium. KUPO:0001104 + renal interstitial pericyte @@ -14770,7 +14813,7 @@ For example, A and B may be gene products and binding of B by A positively regul - A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex). + A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex). https://github.com/geneontology/go-ontology/issues/17729 GO:0008372 NIF_Subcellular:sao1337158144 @@ -14791,7 +14834,7 @@ For example, A and B may be gene products and binding of B by A positively regul - A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex). + A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex). GOC:pdt @@ -14821,8 +14864,8 @@ For example, A and B may be gene products and binding of B by A positively regul + - Note that this term is intended to annotate gene products that are not attached to the cell surface. For gene products from multicellular organisms which are secreted from a cell but retained within the organism (i.e. released into the interstitial fluid or blood), consider the cellular component term 'extracellular space ; GO:0005615'. extracellular region @@ -14867,32 +14910,32 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + A protein complex consisting of three collagen chains assembled into a left-handed triple helix. These trimers typically assemble into higher order structures. Wikipedia:Collagen cellular_component GO:0005581 collagen trimer - + - + - + PMID:12382326 - + PMID:12382326 @@ -14974,7 +15017,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Note that for multicellular organisms, the extracellular space refers to everything outside a cell, but still within the organism (excluding the extracellular matrix). Gene products from a multi-cellular organism that are secreted from a cell into the interstitial fluid or blood can therefore be annotated to this term. extracellular space @@ -15114,8 +15157,8 @@ For example, A and B may be gene products and binding of B by A positively regul + - Chromosomes include parts that are not part of the chromatin. Examples include the kinetochore. chromosome @@ -15181,8 +15224,8 @@ For example, A and B may be gene products and binding of B by A positively regul + - cytoplasm @@ -15342,8 +15385,8 @@ For example, A and B may be gene products and binding of B by A positively regul + - ribosome @@ -15384,8 +15427,8 @@ For example, A and B may be gene products and binding of B by A positively regul + - cytoskeleton @@ -15470,8 +15513,8 @@ For example, A and B may be gene products and binding of B by A positively regul + - plasma membrane @@ -15689,7 +15732,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + translation @@ -15817,7 +15860,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Note that this term should not be used for direct annotation. It should be possible to make a more specific annotation to one of the children of this term, for e.g. to transmembrane transport, to microtubule-based transport or to vesicle-mediated transport. transport @@ -16146,8 +16189,8 @@ For example, A and B may be gene products and binding of B by A positively regul + - cytoskeleton organization @@ -16933,7 +16976,7 @@ For example, A and B may be gene products and binding of B by A positively regul necrosis GO:0008219 - This term should not be used for direct annotation, it is currently kept in GO as a placeholder for describing cell death phenotypes in uPHENO. When information is provided on a programmed cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'). Unintentional cell death, i.e. cell death caused by injury, ageing, or cell phenotypes observed as a result of a pathological mutation in an essential gene should NOT be annotated using GO terms. + This term should not be used for direct annotation, it is currently kept in GO as a placeholder for describing cell death phenotypes in uPHENO. When information is provided on a programmed cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'). Unintentional cell death, i.e. cell death caused by injury, ageing, or cell phenotypes observed as a result of a pathological mutation in an essential gene should NOT be annotated using GO terms. cell death @@ -17439,7 +17482,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Note that this term should be used to annotate gene products in the organism undergoing the programmed cell death. To annotate genes in another organism whose products modulate programmed cell death in a host organism, consider the term 'modulation by symbiont of host programmed cell death ; GO:0052040'. Also, note that 'programmed cell death ; GO:0012501' should be used to refer to instances of caspase-independent cell death mechanisms, in the absence of further indications on the process taking place. At present, caspase-independent cell death is not yet represented in GO due to the lack of consensus and in-depth research on the topic. 'programmed cell death ; GO:0012501' may also be used to annotate gene products in taxa where apoptosis as defined in GO:0006915 does not occur, such as plants. You may also consider these specific children: GO:0097468 'programmed cell death in response to reactive oxygen species' (with descendants GO:0010421 'hydrogen peroxide-mediated programmed cell death' and GO:0010343 'singlet oxygen-mediated programmed cell death'), and GO:0009626 'plant-type hypersensitive response' and its children. programmed cell death @@ -18371,8 +18414,8 @@ For example, A and B may be gene products and binding of B by A positively regul + - Note that a signal is any variable property or parameter that serves to convey information, and may be a physical entity such as a gene product or small molecule, a photon, or a change in state such as movement or voltage change. signaling @@ -18464,7 +18507,7 @@ For example, A and B may be gene products and binding of B by A positively regul cell projection organization and biogenesis cell surface structure organization and biogenesis GO:0030030 - + cell projection organization @@ -19004,7 +19047,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + extracellular matrix @@ -20238,7 +20281,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + cell projection @@ -20323,6 +20366,7 @@ For example, A and B may be gene products and binding of B by A positively regul The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. + https://github.com/geneontology/go-ontology/issues/26424 GO:0034960 GO:0043283 GO:0044259 @@ -20332,6 +20376,7 @@ For example, A and B may be gene products and binding of B by A positively regul multicellular organismal macromolecule metabolic process biological_process GO:0043170 + macromolecule metabolic process @@ -20362,7 +20407,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + organelle @@ -20785,9 +20830,11 @@ For example, A and B may be gene products and binding of B by A positively regul The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism. + https://github.com/geneontology/go-ontology/issues/26424 primary metabolism biological_process GO:0044238 + primary metabolic process @@ -21568,9 +21615,11 @@ For example, A and B may be gene products and binding of B by A positively regul The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. + https://github.com/geneontology/go-ontology/issues/26424 development of an anatomical structure biological_process GO:0048856 + @@ -21618,7 +21667,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + cell motility @@ -21901,7 +21950,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. response to stimulus @@ -22838,7 +22887,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + protein-containing complex assembly @@ -23242,6 +23291,7 @@ For example, A and B may be gene products and binding of B by A positively regul The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon. + https://github.com/geneontology/go-ontology/issues/26424 mah 2010-03-08T03:32:18Z organic molecular entity metabolic process @@ -23249,6 +23299,7 @@ For example, A and B may be gene products and binding of B by A positively regul organic substance metabolism biological_process GO:0071704 + organic substance metabolic process @@ -23362,7 +23413,7 @@ For example, A and B may be gene products and binding of B by A positively regul - The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures. + The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures. mah 2010-10-04T01:51:47Z cellular_component @@ -23373,7 +23424,7 @@ For example, A and B may be gene products and binding of B by A positively regul - The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures. + The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures. GOC:pdt @@ -24402,6 +24453,7 @@ For example, A and B may be gene products and binding of B by A positively regul A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex but below that of an anatomical system. Or, a substance produced by a cellular organism with granularity above the level of a protein complex. https://github.com/geneontology/go-ontology/issues/24200 + https://github.com/geneontology/go-ontology/issues/26424 kmv 2019-08-12T18:01:37Z cellular_component @@ -25746,57 +25798,6 @@ For example, A and B may be gene products and binding of B by A positively regul - - - - - quality - PATO:0000068 - TODO: define this or obsolete it and move children somewhere else. - qualitative - - - - - - - - - A quality inhering in a bearer by virtue of the whether the bearer differs from normal or average. - quality - PATO:0000069 - - deviation (from_normal) - - - - - A quality inhering in a bearer by virtue of the whether the bearer differs from normal or average. - PATOC:GVG - - - - - - - - - A morphology quality inhering in a bearer by virtue of the bearer's physical magnitude. - quality - PATO:0000117 - - - size - - - - - A morphology quality inhering in a bearer by virtue of the bearer's physical magnitude. - WordNet:WordNet - - - - @@ -25872,67 +25873,6 @@ For example, A and B may be gene products and binding of B by A positively regul - - - - - A quality inhering in a bearer by virtue of the bearer's exhibiting no deviation from normal or average. - - quality - average - PATO:0000461 - - - - normal - - - - - A quality inhering in a bearer by virtue of the bearer's exhibiting no deviation from normal or average. - PATOC:GVG - - - - - - - - - - - - - - - - - - - - - A size quality which is relatively high. - - PATO:0001202 - quality - big - enlarged - expanded - great - large - PATO:0000586 - - increased size - - - - - A size quality which is relatively high. - PATOC:GVG - - - - @@ -26666,77 +26606,6 @@ For example, A and B may be gene products and binding of B by A positively regul - - - - - - - - - - - - - - - - - - - - - - A quality that has a value that is increased compared to normal or average. - - - 2011-06-16T06:39:43Z - quality - PATO:0002300 - increased quality - - - - - A quality that has a value that is increased compared to normal or average. - PATOC:GVG - - - - - - - - - - - - - - - - - - - - - A quality of an object that has a value that is increased compared to normal or average. - - - 2011-06-16T06:54:01Z - quality - PATO:0002305 - increased object quality - - - - - A quality of an object that has a value that is increased compared to normal or average. - PATOC:GVG - - - - @@ -26907,6 +26776,28 @@ For example, A and B may be gene products and binding of B by A positively regul + + + + + A quality inhering in a cell by virtue of the cell having a high nuclear/cytoplasmic ratio. + http://orcid.org/0000-0001-5208-3432 + high N:C ratio + quality + PATO:0040072 + A high nuclear/cytolasmic ratio is 70% or higher. + high nuclear/cytoplasmic ratio + + + + + A quality inhering in a cell by virtue of the cell having a high nuclear/cytoplasmic ratio. + Wikipedia:NC_ratio&oldid=931936284 + http://lymerick.net/blood-cells.pdf + + + + @@ -28250,6 +28141,12 @@ For example, A and B may be gene products and binding of B by A positively regul EMAPA:37283 MA:th + + + + FBbt:00007000 + + @@ -28325,7 +28222,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -28385,14 +28282,14 @@ For example, A and B may be gene products and binding of B by A positively regul ureter https://upload.wikimedia.org/wikipedia/commons/3/30/Urinary_system.svg - + - + GO @@ -28464,8 +28361,8 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + @@ -28515,25 +28412,25 @@ For example, A and B may be gene products and binding of B by A positively regul urethra https://upload.wikimedia.org/wikipedia/commons/c/cb/Female_anatomy.png - + - + - + pelvic part of UG sinus gives rise to prostatic and membranous parts of urethra Wikipedia - + Wikipedia @@ -28611,6 +28508,12 @@ For example, A and B may be gene products and binding of B by A positively regul A tube shaped portion of tissue lined with epithelial cells that collects secretions and routes them to their destination[ZFA:0005171]. ZFA:0005171 + + + + FBbt:00100314 + + @@ -28732,6 +28635,12 @@ For example, A and B may be gene products and binding of B by A positively regul Material anatomical entity that is a single connected structure with inherent 3D shape generated by coordinated expression of the organism's own genome. CARO:0000003 + + + + FBbt:00007001 + + @@ -29080,7 +28989,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -29131,14 +29040,14 @@ For example, A and B may be gene products and binding of B by A positively regul http://upload.wikimedia.org/wikipedia/commons/3/30/Gray1130.svg https://upload.wikimedia.org/wikipedia/commons/2/22/Renal_corpuscle.svg - + - + FMA MA @@ -29203,7 +29112,7 @@ For example, A and B may be gene products and binding of B by A positively regul glomerulus renis Wikipedia:Glomerulus - + @@ -29435,15 +29344,15 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + - + @@ -29479,34 +29388,34 @@ For example, A and B may be gene products and binding of B by A positively regul metanephros - + - + - + - + definitional - + GO - + ISBN:9780878932504 @@ -29645,7 +29554,7 @@ For example, A and B may be gene products and binding of B by A positively regul tubuli mesonephrici Wikipedia:Mesonephric_tubules - + @@ -29663,8 +29572,8 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + An epithelial swelling on the Wolffian duct that elongates to invade the adjacent metanephric mesenchyme[MP]. Outgrowth of the mesonephric duct that penetrates the metanephric mesoderm and forms the ureter, renal pelvis, major and minor calyces and collecting ducts. [Embryology, See_Dudek_RW_and_Fix_JD, Third_Edition_(2004)_Philadelphia:_Lippincott_William_and_Wilkins, p.137][VHOG] Outgrowth of the mesonephric duct that penetrates the metanephric mesoderm and forms the ureter, renal pelvis, major and minor calyces and collecting ducts[VHOG:0000541]. @@ -29691,11 +29600,11 @@ For example, A and B may be gene products and binding of B by A positively regul ureteric bud - + - + @@ -29708,13 +29617,13 @@ For example, A and B may be gene products and binding of B by A positively regul - + EHDAA2 - + ISBN:9780878932504 @@ -29766,14 +29675,14 @@ For example, A and B may be gene products and binding of B by A positively regul diverticulum metanephricum Wikipedia:Ureteric_bud - + gemma ureterica Wikipedia:Ureteric_bud - + @@ -29998,7 +29907,9 @@ For example, A and B may be gene products and binding of B by A positively regul IDOMAL:0000302 - https://orcid.org/0000-0003-4423-4370 + + + https://github.com/biopragmatics/biomappings @@ -30023,7 +29934,7 @@ For example, A and B may be gene products and binding of B by A positively regul zygotum Wikipedia:Zygote - + @@ -30147,7 +30058,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -30183,14 +30094,14 @@ For example, A and B may be gene products and binding of B by A positively regul gastrula stage - + - + BILS @@ -30468,8 +30379,8 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + @@ -30502,24 +30413,24 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0000162 cloaca - + - + - + ZFA - + AAO @@ -30601,8 +30512,8 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + @@ -30621,24 +30532,24 @@ For example, A and B may be gene products and binding of B by A positively regul embryonic cloaca - + - + - + EHDAA2 - + EHDAA2 @@ -30661,7 +30572,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -30703,14 +30614,14 @@ For example, A and B may be gene products and binding of B by A positively regul primitive urogenital sinus http://upload.wikimedia.org/wikipedia/commons/6/6d/Gray1109.png - + - + MP-def @@ -30774,7 +30685,7 @@ For example, A and B may be gene products and binding of B by A positively regul sinus urogenitalis - + @@ -30910,6 +30821,12 @@ For example, A and B may be gene products and binding of B by A positively regul in FMA, the tongue, palate etc are part of the mouth which is itself a subdivision of the face. ZFA includes a separate class 'oral region' which is part of the mouth, but excludes tongue and lips FMA + + + + FBbt:00003126 + + @@ -30917,14 +30834,14 @@ For example, A and B may be gene products and binding of B by A positively regul BTO:0004698 FMA:49184 FMA:TA - + cavital oralis Wikipedia:Mouth - + @@ -31066,15 +30983,15 @@ For example, A and B may be gene products and binding of B by A positively regul - + - - + + A fluid that is composed of blood plasma and erythrocytes. This class excludes blood analogues, such as the insect analog of blood. See UBERON:0000179 haemolymphatic fluid. @@ -31116,34 +31033,34 @@ For example, A and B may be gene products and binding of B by A positively regul blood - + - + - + - + CL:tm - + https://github.com/obophenotype/uberon/issues/1330 - + Bgee:AN @@ -31338,6 +31255,7 @@ For example, A and B may be gene products and binding of B by A positively regul parenchymal Early in development the mammalian embryo has three distinct layers: ectoderm (external layer), endoderm (internal layer) and in between those two layers the middle layer or mesoderm. The parenchyma of most organs is of ectodermal (brain, skin) or endodermal origin (lungs, gastrointestinal tract, liver, pancreas). The parenchyma of a few organs (spleen, kidneys, heart) is of mesodermal origin. The stroma of all organs is of mesodermal origin the FMA definition is more restrictive, and limits this to solid organs. This would seem to cause problems for the lung parenchyma, except FMA classifies Lung as solid rather than cavitated + BTO:0000999 BTO:0001539 EHDAA:3015 EHDAA:3905 @@ -31377,11 +31295,21 @@ For example, A and B may be gene products and binding of B by A positively regul the FMA definition is more restrictive, and limits this to solid organs. This would seem to cause problems for the lung parenchyma, except FMA classifies Lung as solid rather than cavitated FMA + + + + BTO:0000999 + + + https://github.com/biopragmatics/biomappings + BTO:0001539 - https://orcid.org/0000-0003-4423-4370 + + + https://github.com/biopragmatics/biomappings @@ -31499,7 +31427,7 @@ For example, A and B may be gene products and binding of B by A positively regul medulla renalis FMA:74268 FMA:TA - + @@ -31507,7 +31435,7 @@ For example, A and B may be gene products and binding of B by A positively regul pyramides renales FMA:74268 FMA:TA - + @@ -31683,7 +31611,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -31725,14 +31653,14 @@ For example, A and B may be gene products and binding of B by A positively regul organism substance - + - + this relationship may be too strong and may be weakened in future @@ -31741,6 +31669,12 @@ For example, A and B may be gene products and binding of B by A positively regul Material anatomical entity in a gaseous, liquid, semisolid or solid state; produced by anatomical structures or derived from inhaled and ingested substances that have been modified by anatomical structures as they pass through the body. http://orcid.org/0000-0001-9114-8737 + + + + FBbt:00007019 + + @@ -31819,6 +31753,12 @@ For example, A and B may be gene products and binding of B by A positively regul Non-material anatomical entity of three dimensions, that is generated by morphogenetic or other physiologic processes; is surrounded by one or more anatomical structures; contains one or more organism substances or anatomical structures. http://orcid.org/0000-0001-9114-8737 + + + + FBbt:00007017 + + @@ -31868,6 +31808,12 @@ For example, A and B may be gene products and binding of B by A positively regul Anatomical entity that has mass. http://orcid.org/0000-0001-9114-8737 + + + + FBbt:00007016 + + @@ -31904,6 +31850,12 @@ For example, A and B may be gene products and binding of B by A positively regul Anatomical entity that has no mass. http://orcid.org/0000-0001-9114-8737 + + + + FBbt:00007015 + + @@ -31989,11 +31941,19 @@ For example, A and B may be gene products and binding of B by A positively regul system GO:0048731 + + + + FBbt:00004856 + + IDOMAL:0002460 - https://orcid.org/0000-0003-4423-4370 + + + https://github.com/biopragmatics/biomappings @@ -32092,6 +32052,12 @@ For example, A and B may be gene products and binding of B by A positively regul VHOG:0000671 WBbt:0007833 + + + + FBbt:00000001 + + @@ -32240,6 +32206,12 @@ For example, A and B may be gene products and binding of B by A positively regul CARO:DOS http://orcid.org/0000-0001-9114-8737 + + + + FBbt:00007009 + + @@ -32307,6 +32279,12 @@ For example, A and B may be gene products and binding of B by A positively regul Anatomical structure that consists of cell parts and cell substances and together does not constitute a cell or a tissue. http://orcid.org/0000-0001-9114-8737 + + + + FBbt:00007013 + + @@ -32326,7 +32304,6 @@ For example, A and B may be gene products and binding of B by A positively regul FBbt:00007277 - IDOMAL:0002461 VHOG:0001737 uberon UBERON:0000477 @@ -32343,8 +32320,8 @@ For example, A and B may be gene products and binding of B by A positively regul - IDOMAL:0002461 - https://orcid.org/0000-0003-4423-4370 + FBbt:00007277 + @@ -32415,6 +32392,12 @@ For example, A and B may be gene products and binding of B by A positively regul Multicellular anatomical structure that consists of many cells of one or a few types, arranged in an extracellular matrix such that their long-range organisation is at least partly a repetition of their short-range organisation. CARO:0000043 + + + + FBbt:00007003 + + @@ -32482,6 +32465,12 @@ For example, A and B may be gene products and binding of B by A positively regul CARO:0000055 http://orcid.org/0000-0001-9114-8737 + + + + FBbt:00007010 + + @@ -32520,7 +32509,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -32564,14 +32553,14 @@ For example, A and B may be gene products and binding of B by A positively regul epithelium https://upload.wikimedia.org/wikipedia/commons/8/8f/Illu_epithelium.jpg - + - + http://palaeos.com/metazoa/porifera/homoscleromorpha.html @@ -32591,6 +32580,12 @@ For example, A and B may be gene products and binding of B by A positively regul ISBN:978-0030259821 Ruppert EE, Fox RS, Barnes RD, Invertebrate zoology: a functional evolutionary approach (2003) p.59 http://bgee.unil.ch/ + + + + FBbt:00007005 + + @@ -32659,6 +32654,12 @@ For example, A and B may be gene products and binding of B by A positively regul columnar epithlium AEO:0000068 + + + + FBbt:00007027 + + @@ -32954,7 +32955,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -32991,14 +32992,14 @@ For example, A and B may be gene products and binding of B by A positively regul abdomen - + - + MA @@ -33112,11 +33113,19 @@ For example, A and B may be gene products and binding of B by A positively regul Obsoleted in ZFA. Note that embryo is not classified as an embryonic structure - an embryonic structure is only the parts of an embryo ZFA + + + + FBbt:00000052 + + IDOMAL:0000646 - https://orcid.org/0000-0003-4423-4370 + + + https://github.com/biopragmatics/biomappings @@ -33203,6 +33212,12 @@ For example, A and B may be gene products and binding of B by A positively regul embryonic tissue FMA:69069 + + + + FBbt:00000110 + + @@ -33241,7 +33256,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Primary germ layer that is the outer of the embryo's three germ layers and gives rise to epidermis and neural tissue. Primary germ layer that is the outer of the embryonic germ layers and gives rise to epidermis and neural tissue.[AAO] The Bilateria are triploblastic (with true endoderm, mesoderm, and ectoderm) (...).[well established][VHOG] @@ -33279,14 +33294,14 @@ For example, A and B may be gene products and binding of B by A positively regul ectoderm http://upload.wikimedia.org/wikipedia/commons/1/19/Gray32.png - + - + Bgee:AN @@ -33314,6 +33329,12 @@ For example, A and B may be gene products and binding of B by A positively regul ISBN:978-0878932504 Gilbert SF, Developmental Biology (2006) Limb development and evolution, p.722 http://bgee.unil.ch/ + + + + FBbt:00000111 + + @@ -33339,7 +33360,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Primary germ layer that lies remote from the surface of the embryo and gives rise to internal tissues such as gut. The Bilateria are triploblastic (with true endoderm, mesoderm, and ectoderm) (...).[well established][VHOG] endodermal @@ -33376,14 +33397,14 @@ For example, A and B may be gene products and binding of B by A positively regul http://upload.wikimedia.org/wikipedia/commons/c/c0/Endoderm2.png http://upload.wikimedia.org/wikipedia/commons/d/df/Gray10.png - + - + Bgee:AN @@ -33402,6 +33423,12 @@ For example, A and B may be gene products and binding of B by A positively regul ISBN:978-0878932504 Gilbert SF, Developmental Biology (2006) Limb development and evolution, p.722 http://bgee.unil.ch/ + + + + FBbt:00000125 + + @@ -33428,7 +33455,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + The middle germ layer of the embryo, between the endoderm and ectoderm. Primary germ layer that is the middle of the embryonic germ layers.[AAO] @@ -33473,7 +33500,7 @@ For example, A and B may be gene products and binding of B by A positively regul mesoderm http://upload.wikimedia.org/wikipedia/commons/e/e8/Mesoderm.png - + @@ -33486,7 +33513,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Bgee:AN @@ -33520,6 +33547,12 @@ For example, A and B may be gene products and binding of B by A positively regul sponges do not seem to have a mesoderm and accordingly Amphimedon lacks transcription factors involved in mesoderm development (Fkh, Gsc, Twist, Snail)[http://www.nature.com/nature/journal/v466/n7307/full/nature09201.html]. Mesoderm may not be homologous across verteberates https://github.com/obophenotype/uberon/wiki/The-neural-crest + + + + FBbt:00000126 + + @@ -33629,6 +33662,12 @@ For example, A and B may be gene products and binding of B by A positively regul stomodeal-hypophyseal primordium XAO:0000269 + + + + FBbt:00000439 + + @@ -33685,7 +33724,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -33731,7 +33770,7 @@ For example, A and B may be gene products and binding of B by A positively regul proctodeum https://github.com/obophenotype/uberon/issues/685 - + @@ -33744,7 +33783,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + EHDAA2 @@ -33773,6 +33812,12 @@ For example, A and B may be gene products and binding of B by A positively regul AAO ZFA:0000066 + + + + FBbt:00000123 + + @@ -33818,7 +33863,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -33895,14 +33940,14 @@ For example, A and B may be gene products and binding of B by A positively regul https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Heart.glb https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Heart.glb - + - + MA @@ -34218,6 +34263,7 @@ For example, A and B may be gene products and binding of B by A positively regul Anatomical system that has as its parts the organs concerned with reproduction. consider splitting genitalia from reproductive system + Anatomical system which consists of organs and tissues associated with sexual reproduction of the organism.[AAO] Arguably, one of the most important aspects of urbilaterian organogenesis would have been gonadogenesis, since Urbilateria must have successfully generated gametes and developed a strategy for extrusion and fertilization, in order to be the ancestor of all living Bilateria.[well established][VHOG] @@ -34237,6 +34283,7 @@ For example, A and B may be gene products and binding of B by A positively regul HAO:0000374 HAO:0000895 MA:0000326 + MESH:D005835 MIAA:0000305 NCIT:C12841 SCTID:278875001 @@ -34260,6 +34307,7 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0000990 + @@ -34291,6 +34339,19 @@ For example, A and B may be gene products and binding of B by A positively regul PMID:21672850 Extavour CGM, Gray anatomy: phylogenetic patterns of somatic gonad structures and reproductive strategies across Bilateria. Integrative and Comparative Biology (2007) http://bgee.unil.ch/ + + + + FBbt:00004857 + + + + + + MESH:D005835 + + https://github.com/biopragmatics/biomappings + @@ -34332,7 +34393,7 @@ For example, A and B may be gene products and binding of B by A positively regul systemata genitalia Wikipedia:Reproductive_system - + @@ -34450,6 +34511,12 @@ For example, A and B may be gene products and binding of B by A positively regul FMA xref is a 'general anatomical term' FMA + + + + FBbt:00004858 + + @@ -34562,6 +34629,12 @@ For example, A and B may be gene products and binding of B by A positively regul many anatomy ontologies consider gastrointestinal system synonymous with digestive system. here we follow MA in dividing digestive system into gastrointestinal and hepatobiliary. hepatobiliary includes the liver and biliary tract. species-specific AO classes are categorized according to whether liver is included. For example, XAO includes liver as part of XAO:0000125 alimentary system, so we assume this class is the more generic class MA + + + + FBbt:00005055 + + @@ -34701,6 +34774,12 @@ For example, A and B may be gene products and binding of B by A positively regul This definition is inclusive of the organs of the vertebrate renal system, as well as the Malpighian tubules of insects, and allows for future incorporation of structures such as the antennal glands of crustaceans DOI:10.1371/journal.pone.0099864 + + + + FBbt:00005056 + + @@ -34766,6 +34845,7 @@ For example, A and B may be gene products and binding of B by A positively regul We should divest ourselves of the view that earlier vertebrate groups were 'on their way' to becoming mammals, as clearly they were not such visionaries. Neither were their systems 'imperfect' as earlier anatomists thought. Instead, their circulatory systems served them well to address the ecological demands arising from their lifestyles.[well established][VHOG] AAO:0000959 CALOHA:TS-2103 + MESH:D002319 VHOG:0001248 Wikipedia:Circulatory_system uberon @@ -34813,12 +34893,19 @@ For example, A and B may be gene products and binding of B by A positively regul ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.493 http://bgee.unil.ch/ + + + + MESH:D002319 + + https://github.com/biopragmatics/biomappings + systema cardiovasculare Wikipedia:Circulatory_system - + @@ -34899,7 +34986,7 @@ For example, A and B may be gene products and binding of B by A positively regul musculi FMA:32558 FMA:TA - + @@ -34950,13 +35037,14 @@ For example, A and B may be gene products and binding of B by A positively regul - + The nervous system is an organ system containing predominantly neuron and glial cells. In bilaterally symmetrical organism, it is arranged in a network of tree-like structures connected to a central body. The main functions of the nervous system are to regulate and control body functions, and to receive sensory input, process this information, and generate behavior [CUMBO]. + A regulatory system of the body that consists of neurons and neuroglial cells. The nervous system is divided into two parts, the central nervous system (CNS) and the peripheral nervous system (PNS). (Source: BioGlossary, www.Biology-Text.com)[TAO] Anatomical system consisting of nerve bodies and nerve fibers which regulate the response of the body to external and internal stimuli.[AAO] Nervous systems evolved in the ancestor of Eumetazoa.[well established][VHOG] @@ -34996,6 +35084,7 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0001016 + @@ -35003,14 +35092,14 @@ For example, A and B may be gene products and binding of B by A positively regul http://upload.wikimedia.org/wikipedia/commons/b/b2/TE-Nervous_system_diagram.svg http://upload.wikimedia.org/wikipedia/commons/b/ba/Nervous_system_diagram.png - + - + Bgee:AN @@ -35053,6 +35142,12 @@ For example, A and B may be gene products and binding of B by A positively regul ISBN:978-0198566694 Schmidt-Rhaesa A, The evolution of organ systems (2007) p.117 http://bgee.unil.ch/ + + + + FBbt:00005093 + + @@ -35076,7 +35171,7 @@ For example, A and B may be gene products and binding of B by A positively regul systema nervosum Wikipedia:Nervous_system - + @@ -35098,9 +35193,10 @@ For example, A and B may be gene products and binding of B by A positively regul - + The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the neural tube derivatives: the brain and spinal cord. In invertebrates it includes central ganglia plus nerve cord. + Part of the nervous system which includes the brain and spinal cord.[AAO] The brain and spinal cord. Kimmel et al, 1995.[TAO] The central nervous system (CNS) is the part of the nervous system which includes the brain, spinal cord, and nerve cell layer of the retina (CUMBO). @@ -35140,12 +35236,13 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0001017 + central nervous system - + @@ -35159,7 +35256,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Bgee:AN @@ -35210,6 +35307,12 @@ For example, A and B may be gene products and binding of B by A positively regul ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.28 (reference 1), ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.165 (reference 2), DOI:10.1016/j.cell.2007.02.040 Denes AS, Jekely G, Steinmetz PRH, Raible F, Snyman H, Prud'homme B, Ferrier DEK, Balavoine G and Arendt D, Molecular architecture of annelid nerve cord supports common origin of nervous system centralization in Bilateria. Cell (2007) (reference 3) http://bgee.unil.ch/ + + + + FBbt:00005094 + + @@ -35229,7 +35332,7 @@ For example, A and B may be gene products and binding of B by A positively regul systema nervosum centrale FMA:55675 FMA:TA - + @@ -35302,6 +35405,12 @@ For example, A and B may be gene products and binding of B by A positively regul ISBN:978-0030259821 Ruppert EE, Fox RS, Barnes RD, Invertebrate zoology: a functional evolutionary approach (2003) p.203, ISBN:978-0521617147 Stevens CE and Hume ID, Comparative physiology of the vertebrate digestive system (2004) p.11 http://bgee.unil.ch/ + + + + FBbt:00005379 + + @@ -35313,14 +35422,14 @@ For example, A and B may be gene products and binding of B by A positively regul praeenteron Wikipedia:Foregut - + proenteron Wikipedia:Foregut - + @@ -35395,6 +35504,12 @@ For example, A and B may be gene products and binding of B by A positively regul in FMA this represents an embryonic region. FMA + + + + FBbt:00005383 + + @@ -35406,7 +35521,7 @@ For example, A and B may be gene products and binding of B by A positively regul mesenteron Wikipedia:Midgut - + @@ -35415,7 +35530,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -35452,14 +35567,14 @@ For example, A and B may be gene products and binding of B by A positively regul hindgut http://upload.wikimedia.org/wikipedia/commons/f/f7/Gray472.png - + - + Wikipedia @@ -35490,6 +35605,12 @@ For example, A and B may be gene products and binding of B by A positively regul in FMA this class has no children. In MA it has a single child hindgut epithelium FMA + + + + FBbt:00005384 + + @@ -35501,7 +35622,7 @@ For example, A and B may be gene products and binding of B by A positively regul metenteron Wikipedia:Hindgut - + @@ -35555,6 +35676,12 @@ For example, A and B may be gene products and binding of B by A positively regul FB:FBrf0089570 http://flybase.org/reports/FBrf0178740.html + + + + FBbt:00005495 + + @@ -35675,6 +35802,14 @@ For example, A and B may be gene products and binding of B by A positively regul The mature structure of the neural tube exists when the tube has been segmented into the forebrain, midbrain, hindbrain and spinal cord regions. In addition neural crest has budded away from the epithelium GO:0021915 + + + + MESH:D054259 + + + https://github.com/biopragmatics/biomappings + @@ -35686,7 +35821,7 @@ For example, A and B may be gene products and binding of B by A positively regul tubus neuralis Wikipedia:Neural_tube - + @@ -35729,6 +35864,12 @@ For example, A and B may be gene products and binding of B by A positively regul FMA:62955 http://orcid.org/0000-0001-9114-8737 + + + + FBbt:10000000 + + @@ -35857,7 +35998,7 @@ For example, A and B may be gene products and binding of B by A positively regul vena cava inferior BTO:0002682 Wikipedia:Inferior_vena_cava - + @@ -36024,7 +36165,7 @@ For example, A and B may be gene products and binding of B by A positively regul venae renales Wikipedia:Renal_vein - + @@ -36034,14 +36175,14 @@ For example, A and B may be gene products and binding of B by A positively regul - + - + @@ -36093,24 +36234,24 @@ For example, A and B may be gene products and binding of B by A positively regul renal pelvis https://upload.wikimedia.org/wikipedia/commons/c/c0/Illu_kidney2.jpg - + - + - + MA - + FMA @@ -36130,7 +36271,7 @@ For example, A and B may be gene products and binding of B by A positively regul p. renallis Wikipedia:Renal_pelvis - + @@ -36156,7 +36297,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -36193,14 +36334,14 @@ For example, A and B may be gene products and binding of B by A positively regul https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Kidney_R.glb https://upload.wikimedia.org/wikipedia/commons/6/69/Illu_kidney.jpg - + - + FMA @@ -36221,7 +36362,7 @@ For example, A and B may be gene products and binding of B by A positively regul cortex renalis FMA:15581 FMA:TA - + @@ -36236,7 +36377,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -36284,14 +36425,14 @@ For example, A and B may be gene products and binding of B by A positively regul renal corpuscle https://upload.wikimedia.org/wikipedia/commons/2/22/Renal_corpuscle.svg - + - + MA ZFA @@ -36352,14 +36493,14 @@ For example, A and B may be gene products and binding of B by A positively regul corpusculum renale - + corpusculum renis Wikipedia:Renal_corpuscle - + @@ -36392,7 +36533,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -36437,14 +36578,14 @@ For example, A and B may be gene products and binding of B by A positively regul glomerular capsule http://upload.wikimedia.org/wikipedia/commons/3/30/Gray1130.svg - + - + Wikipedia @@ -36486,7 +36627,7 @@ For example, A and B may be gene products and binding of B by A positively regul capsula glomerularis - + @@ -36529,7 +36670,7 @@ For example, A and B may be gene products and binding of B by A positively regul capsula glomeruli - + @@ -36543,11 +36684,11 @@ For example, A and B may be gene products and binding of B by A positively regul - + - - + + @@ -36586,7 +36727,7 @@ For example, A and B may be gene products and binding of B by A positively regul nephron tubule - + @@ -36595,18 +36736,18 @@ For example, A and B may be gene products and binding of B by A positively regul - + - + - + GO MA ZFA @@ -36620,13 +36761,13 @@ For example, A and B may be gene products and binding of B by A positively regul - + ZFA - + checkme @@ -36667,7 +36808,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -36715,14 +36856,14 @@ For example, A and B may be gene products and binding of B by A positively regul collecting duct of renal tubule - + - + checkme GO @@ -36765,7 +36906,7 @@ For example, A and B may be gene products and binding of B by A positively regul tubulus renalis arcuatus Wikipedia:Connecting_tubule - + @@ -36867,6 +37008,12 @@ For example, A and B may be gene products and binding of B by A positively regul Wikipedia:Anus ZFIN:curator + + + + FBbt:00047153 + + @@ -36882,8 +37029,8 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + Distensible musculomembranous organ situated in the anterior part of the pelvic cavity in which urine collects before excretion[MP]. @@ -36930,11 +37077,11 @@ For example, A and B may be gene products and binding of B by A positively regul https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Urinary_Bladder.glb https://upload.wikimedia.org/wikipedia/commons/3/30/Urinary_system.svg - + - + @@ -36947,13 +37094,13 @@ For example, A and B may be gene products and binding of B by A positively regul - + FMA - + upper part of UG sinus @@ -37016,7 +37163,7 @@ For example, A and B may be gene products and binding of B by A positively regul vesica urinaria Wikipedia:Urinary_bladder - + @@ -37136,15 +37283,15 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + - + The basic functional unit of the kidney. its chief function is to regulate the concentration of water and soluble substances like sodium salts by filtering the blood, reabsorbing what is needed and excreting the rest as urine. A nephron eliminates wastes from the body, regulates blood volume and blood pressure, controls levels of electrolytes and metabolites, and regulates blood pH. Its functions are vital to life and are regulated by the endocrine system by hormones such as antidiuretic hormone, aldosterone, and parathyroid hormone.[WP]. kidney terms require review for cross-vertebrate compatibility and developmental relationships. @@ -37177,34 +37324,34 @@ For example, A and B may be gene products and binding of B by A positively regul nephron http://upload.wikimedia.org/wikipedia/commons/0/02/Gray1128.png - + - + - + - + FMA - + definitional - + Bgee:AN @@ -37246,14 +37393,14 @@ For example, A and B may be gene products and binding of B by A positively regul nephroneum Wikipedia:Nephron - + tubulus renalis Wikipedia:Nephron - + @@ -37264,15 +37411,15 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + - + @@ -37309,15 +37456,15 @@ For example, A and B may be gene products and binding of B by A positively regul proximal convoluted tubule http://upload.wikimedia.org/wikipedia/commons/0/02/Gray1128.png - + - + - + @@ -37330,20 +37477,20 @@ For example, A and B may be gene products and binding of B by A positively regul - + MA uses subclass GOC:mtg_kidney_jan10 - + GO - + Wikipedia @@ -37384,13 +37531,13 @@ For example, A and B may be gene products and binding of B by A positively regul tubulus contortus proximalis Wikipedia:Proximal_convoluted_tubule - + tubulus convolutus proximalis - + @@ -37500,7 +37647,7 @@ For example, A and B may be gene products and binding of B by A positively regul ansa nephroni Wikipedia:Loop_of_Henle - + @@ -37509,7 +37656,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -37536,7 +37683,7 @@ For example, A and B may be gene products and binding of B by A positively regul descending limb of loop of Henle http://upload.wikimedia.org/wikipedia/commons/0/02/Gray1128.png - + @@ -37549,7 +37696,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + FMA @@ -37573,9 +37720,9 @@ For example, A and B may be gene products and binding of B by A positively regul - - - + + + @@ -37615,15 +37762,15 @@ For example, A and B may be gene products and binding of B by A positively regul proximal straight tubule - + - + - + @@ -37636,20 +37783,20 @@ For example, A and B may be gene products and binding of B by A positively regul - + MA - + MA uses subclass GOC:mtg_kidney_jan10 - + MA @@ -37700,7 +37847,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -37738,7 +37885,7 @@ For example, A and B may be gene products and binding of B by A positively regul distal convoluted tubule https://upload.wikimedia.org/wikipedia/commons/2/21/Kidney_nephron.png - + @@ -37751,7 +37898,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + EMAPA GO MA-modified-from-isa @@ -37779,13 +37926,13 @@ For example, A and B may be gene products and binding of B by A positively regul tubulus contortus distalis Wikipedia:Distal_convoluted_tubule - + tubulus convolutus distalis - + @@ -37844,7 +37991,7 @@ For example, A and B may be gene products and binding of B by A positively regul zona externa (medullaris renalis) FMA:17733 FMA:TA - + @@ -37852,7 +37999,7 @@ For example, A and B may be gene products and binding of B by A positively regul zona externa medullae renalis FMA:17733 FMA:TA - + @@ -37879,7 +38026,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + The anus and surrounding regions. Encompasses both internal and external regions, where present. Although all vertebrates have a digestive tract and accessory glands, various parts of this system are not necessarily homologous, analogous, or even present in all species. Therefore, broad comparisons can be best made under the listings of headgut, foregut, midgut, pancreas and biliary system, hindgut.[uncertain][VHOG] EFO:0000847 @@ -37905,14 +38052,14 @@ For example, A and B may be gene products and binding of B by A positively regul https://github.com/obophenotype/uberon/issues/507 http://upload.wikimedia.org/wikipedia/commons/f/fb/Gray408.png - + - + cjm @@ -38099,7 +38246,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -38122,14 +38269,14 @@ For example, A and B may be gene products and binding of B by A positively regul kidney arcuate artery https://upload.wikimedia.org/wikipedia/commons/8/87/2610_The_Kidney.jpg - + - + MA @@ -38170,7 +38317,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + A tube extending from the mouth to the anus. @@ -38191,6 +38338,7 @@ For example, A and B may be gene products and binding of B by A positively regul FBbt:00003125 FMA:45615 MA:0000917 + MESH:D041981 NCIT:C34082 TAO:0000112 TGMA:0001819 @@ -38212,14 +38360,14 @@ For example, A and B may be gene products and binding of B by A positively regul digestive tract - + - + NCBIBook:NBK10107 @@ -38272,6 +38420,19 @@ For example, A and B may be gene products and binding of B by A positively regul we place the MA and EMAPA class here, although the intent is probably a smaller region. See https://github.com/obophenotype/uberon/issues/509 MA + + + + FBbt:00003125 + + + + + + MESH:D041981 + + https://github.com/biopragmatics/biomappings + @@ -38316,12 +38477,14 @@ For example, A and B may be gene products and binding of B by A positively regul Subdivision of urinary system which consists of the urinary bladder and the urethra. + FMA:45659 MA:0002636 SCTID:181420004 galen:LowerUrinaryTract uberon UBERON:0001556 + lower urinary tract @@ -38637,7 +38800,7 @@ For example, A and B may be gene products and binding of B by A positively regul vena Wikipedia:Vein - + @@ -38864,7 +39027,7 @@ For example, A and B may be gene products and binding of B by A positively regul venula Wikipedia:Venule - + @@ -38973,7 +39136,7 @@ For example, A and B may be gene products and binding of B by A positively regul arteriola Wikipedia:Arteriole - + @@ -38989,8 +39152,8 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + @@ -39003,7 +39166,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -39062,34 +39225,34 @@ For example, A and B may be gene products and binding of B by A positively regul blood vessel http://upload.wikimedia.org/wikipedia/commons/2/29/Circulatory_System_en.svg - + - + - + - + AEO - + EHDAA2 - + GO:0072360 @@ -39162,7 +39325,7 @@ For example, A and B may be gene products and binding of B by A positively regul vas sanguineum Wikipedia:Blood_vessel - + @@ -39499,6 +39662,12 @@ For example, A and B may be gene products and binding of B by A positively regul in FMA embryo is_a embryonic structure FMA + + + + FBbt:00004208 + + @@ -39741,7 +39910,7 @@ For example, A and B may be gene products and binding of B by A positively regul atrium dextrum Wikipedia:Right_atrium - + @@ -39907,6 +40076,7 @@ For example, A and B may be gene products and binding of B by A positively regul FMA:71221 MA:0002986 MAT:0000148 + MESH:D013131 MIAA:0000148 TAO:0000317 VHOG:0000317 @@ -39982,6 +40152,13 @@ For example, A and B may be gene products and binding of B by A positively regul EMAPA:37721 MA:th + + + + MESH:D013131 + + https://github.com/biopragmatics/biomappings + @@ -40113,7 +40290,7 @@ For example, A and B may be gene products and binding of B by A positively regul skeleton appendiculare Wikipedia:Appendicular_skeleton - + @@ -40225,7 +40402,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -40238,7 +40415,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -40287,24 +40464,24 @@ For example, A and B may be gene products and binding of B by A positively regul kidney - + - + - + FMA - + definitional @@ -40345,8 +40522,8 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + @@ -40390,11 +40567,11 @@ For example, A and B may be gene products and binding of B by A positively regul Once the more complex mesonephros forms the pronephros undergoes apoptosis in amphibians. In fishes the nephron degenerates but the organ remains and becomes a component of the immune system[Wikipedia:Pronephros]. // TODO - check developmental relationships. Note that we previously include the ZFA/XAO terms under the more specific 'pronephric kidney', but these are now merged. TODO GCI: relationship: capable_of GO:0030104 pronephros - + - + @@ -40407,13 +40584,13 @@ For example, A and B may be gene products and binding of B by A positively regul - + OG - + ZFA @@ -40460,6 +40637,14 @@ For example, A and B may be gene products and binding of B by A positively regul ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.637 http://bgee.unil.ch/ + + + + MESH:D060910 + + + https://github.com/biopragmatics/biomappings + @@ -40635,7 +40820,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -40669,14 +40854,14 @@ For example, A and B may be gene products and binding of B by A positively regul musculoskeletal system - + - + check ctenophore @@ -40790,7 +40975,7 @@ For example, A and B may be gene products and binding of B by A positively regul cavitas thoracis Wikipedia:Thoracic_cavity - + @@ -40806,7 +40991,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -40825,7 +41010,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + An anatomical structure which consists of juxtaglomerular cells, extraglomerular mesangial cells and the macula densa. The juxtaglomerular apparatus lies adjacent to the glomerulus and regulates kidney function by maintaining the blood flow to the kidney and the filtration rate[GO]. a microscopic structure in the kidney, which regulates the function of each nephron. The juxtaglomerular apparatus is named for its proximity to the glomerulus: it is found between the vascular pole of the renal corpuscle and the returning distal convoluted tubule of the same nephron. This location is critical to its function in regulating renal blood flow and glomerular filtration rate. The three cellular components of the apparatus are the macula densa, extraglomerular mesangial cells, and juxtaglomerular cells (also known as granular cells)[WP]. BTO:0005157 @@ -40847,24 +41032,24 @@ For example, A and B may be gene products and binding of B by A positively regul juxtaglomerular apparatus - + - + - + MA - + GO @@ -40884,7 +41069,7 @@ For example, A and B may be gene products and binding of B by A positively regul complexus juxtaglomerularis - + @@ -40995,8 +41180,8 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + @@ -41013,24 +41198,24 @@ For example, A and B may be gene products and binding of B by A positively regul EDITOR_NOTE check MA part_ofs - should be spatially disjoint from renal glomerulus? extraglomerular mesangium - + - + - + MA - + MA @@ -41047,7 +41232,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -41088,14 +41273,14 @@ For example, A and B may be gene products and binding of B by A positively regul EDITOR_NOTE check the FMA placement here; ncit placement of body cavity here probably not correct coelemic cavity lumen - + - + definitional @@ -41128,6 +41313,12 @@ For example, A and B may be gene products and binding of B by A positively regul body cavity BTO:0001707 + + + + FBbt:00005060 + + @@ -41203,9 +41394,9 @@ For example, A and B may be gene products and binding of B by A positively regul - - - + + + @@ -41260,15 +41451,15 @@ For example, A and B may be gene products and binding of B by A positively regul notochord http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + - + - + @@ -41287,19 +41478,19 @@ For example, A and B may be gene products and binding of B by A positively regul - + http://tolweb.org/Chordata/2499 - + ZFA - + EHDAA2 @@ -41374,7 +41565,7 @@ For example, A and B may be gene products and binding of B by A positively regul notochorda Wikipedia:Notochord - + @@ -41384,8 +41575,8 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + Somites are spheres of epithelial cells that form sequentially along the anterior-posterior axis of the embryo through mesenchymal to epithelial transition of the presomitic mesoderm. EDITOR_NOTE currently classified as an epithelial vesicle, consistent with EHDAA2 and https://github.com/obophenotype/uberon/wiki/The-neural-crest. Consider making 'somitic mesoderm' a separate term and correlate with regionalization processes. Consider moving ZFA term to 'trunk somite' as it is part of the trunk @@ -41431,11 +41622,11 @@ For example, A and B may be gene products and binding of B by A positively regul somite http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + - + @@ -41448,13 +41639,13 @@ For example, A and B may be gene products and binding of B by A positively regul - + GOTAX:0000352 - + ZFA @@ -41557,7 +41748,7 @@ For example, A and B may be gene products and binding of B by A positively regul somitus Wikipedia:Somite - + @@ -41566,8 +41757,8 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + The macula densa is an area of specialized cells in the distal tubule that makes contact with the vascular pole of the glomerulus[GO]. not part of a nephron or distal tubule in MA and FMA @@ -41586,24 +41777,24 @@ For example, A and B may be gene products and binding of B by A positively regul macula densa - + - + - + MA - + GO @@ -41633,12 +41824,12 @@ For example, A and B may be gene products and binding of B by A positively regul - - - - - - + + + + + + A specialized region of ectoderm found between the neural ectoderm (neural plate) and non-neural ectoderm and composed of highly migratory pluripotent cells that delaminate in early embryonic development from the dorsal neural tube and give rise to an astounding variety of differentiated cell types[MP]. EDITOR_NOTE consider including subclasses for pre- and post- migratory (e.g. sheets/paths/streams). @@ -41678,66 +41869,66 @@ For example, A and B may be gene products and binding of B by A positively regul http://upload.wikimedia.org/wikipedia/commons/5/5f/Gray644.png https://upload.wikimedia.org/wikipedia/commons/8/8f/Neural_Crest.png - + - + - + - + - + - + - + XAO https://github.com/obophenotype/uberon/wiki/The-neural-crest - + Hall and others restrict NC to vertebrates but we opt for a less restrictive constraint to avoid inconsistencies when areas such as P1 area of pallium in hagfishes inherit cell lineage from telecephalon-contributing NC cells ISBN:0073040584 - + BTO - + PMID:11523831 - + pre migratory https://github.com/obophenotype/uberon/wiki/The-neural-crest - + PMID:11523831 @@ -41805,7 +41996,7 @@ For example, A and B may be gene products and binding of B by A positively regul crista neuralis Wikipedia:Neural_crest - + @@ -41878,6 +42069,12 @@ For example, A and B may be gene products and binding of B by A positively regul DOI:10.1046/j.1469-7580.2001.19910133.x Graham A. The development and evolution of the pharyngeal arches. J Anat (2001) http://bgee.unil.ch/ + + + + FBbt:00001057 + + @@ -41889,7 +42086,7 @@ For example, A and B may be gene products and binding of B by A positively regul epithelium tubi neuralis; neuroectoderma Wikipedia:Neuroectoderm - + @@ -42206,14 +42403,14 @@ For example, A and B may be gene products and binding of B by A positively regul - + - + Anatomical system that is involved in the production of hematopoietic cells. @@ -42258,24 +42455,24 @@ For example, A and B may be gene products and binding of B by A positively regul hematopoietic system - + - + - + FMA - + definitional @@ -42449,7 +42646,7 @@ For example, A and B may be gene products and binding of B by A positively regul epiblastus Wikipedia:Epiblast - + @@ -42529,7 +42726,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Unsegmented field of paraxial mesoderm present posterior to the most recently formed somite pair, from which somites will form. Unsegmented field of paraxial mesoderm present posterior to the most recently formed somite pair, from which somites will form. Kimmel et al, 1995.[TAO] It is reasonable to assume that the proximate invertebrate ancestor of the vertebrates had an amphioxus-like tail bud in its larval stage. This archetypal tail bud would have (...) (3) lacked any component of mesenchyme cells, (4) budded off new mesodermal segments directly, without any intervening zone of presomitic mesoderm (...). Then, early in vertebrate evolution, epithelium-to-mesenchyme interconversions (and the gene networks for effecting them) became prominent features of development. (...) In any case, conspicuous mesenchymal components tended to be added to the vertebrate tail bud itself. In addition, a mesenchymatous presomitic mesoderm (not a part of the tail bud proper) came to intervene between the tail bud and the forming somites.[well established][VHOG] @@ -42554,14 +42751,14 @@ For example, A and B may be gene products and binding of B by A positively regul presomitic mesoderm - + - + Bgee:AN @@ -42621,8 +42818,8 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + In mammals, the pronephric duct is the predecessor of the Wolffian duct[WP]. Duct of the embryonic kidney, present bilaterally ventral to the somites and leading to the anal region where it empties separately from, and just posterior to the anus. Kimmel et al, 1995.[TAO] The first-formed kidney duct, which drains the kidney of most anamniotes and becomes the ductus deferens of male amniotes. [Bemis_WE, Functional_Anatomy_of_the_Vertebrates:_An_Evolutionary_Perspective, Glossary_G-3, Grande_L, Liem_KF, Third_Edition_(2001)_Orlando_Fla.:_Harcourt_College_Publishers, Walker_WF][VHOG] @@ -42646,11 +42843,11 @@ For example, A and B may be gene products and binding of B by A positively regul The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the pronephric kidney[GOC:mtg_kidney_jan10, PMID:15647339, XAO:0000063, ZFA:0000150] pronephric duct - + - + @@ -42663,13 +42860,13 @@ For example, A and B may be gene products and binding of B by A positively regul - + Wikipedia - + XAO @@ -42710,7 +42907,9 @@ For example, A and B may be gene products and binding of B by A positively regul BTO:0005991 - https://orcid.org/0000-0003-4423-4370 + + + https://github.com/biopragmatics/biomappings @@ -42729,7 +42928,7 @@ For example, A and B may be gene products and binding of B by A positively regul ductus pronephricus Wikipedia:Pronephric_duct - + @@ -42856,9 +43055,9 @@ For example, A and B may be gene products and binding of B by A positively regul - - - + + + @@ -42900,34 +43099,34 @@ For example, A and B may be gene products and binding of B by A positively regul intermediate mesoderm http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + - + - + - + AAO - + EMAPA - + XAO @@ -42991,7 +43190,7 @@ For example, A and B may be gene products and binding of B by A positively regul mesenchyma intermedium Wikipedia:Intermediate_mesoderm - + @@ -43072,7 +43271,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Paired organ that connects the primitive kidney Wolffian body (or mesonephros) to the cloaca and serves as the anlage for certain male reproductive organs. the Wolffian duct is what remains of the pronephric duct after the atrophy of the pronephros[WP]. In Zebrafish: Duct of the adult kidney (mesonephros), present bilaterally ventral to the somites and leading to the cloacal chamber[ZFA]. Consider adding subclasses for male and female specific variants TODO - mesonephric portion of the nephric duct @@ -43108,7 +43307,7 @@ For example, A and B may be gene products and binding of B by A positively regul mesonephric duct http://upload.wikimedia.org/wikipedia/commons/6/6d/Gray1109.png - + @@ -43121,7 +43320,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + EHDAA2 @@ -43164,7 +43363,9 @@ For example, A and B may be gene products and binding of B by A positively regul BTO:0005990 - https://orcid.org/0000-0003-4423-4370 + + + https://github.com/biopragmatics/biomappings @@ -43198,7 +43399,7 @@ For example, A and B may be gene products and binding of B by A positively regul ductus mesonephricus; ductus Wolffi Wikipedia:Mesonephric_duct - + @@ -43209,9 +43410,9 @@ For example, A and B may be gene products and binding of B by A positively regul - - - + + + A region of embryonic ectodermal cells that lie directly above the notochord. During neurulation, they change shape and produce an infolding of the neural plate (the neural fold) that then seals to form the neural tube[XAO]. The earliest recognizable dorsal ectodermal primordium of the central nervous system present near the end of gastrulation before infolding to form the neural keel; consists of a thickened pseudostratified epithelium[ZFA]. The earliest recognizable dorsal ectodermal primordium of the central nervous system present near the end of gastrulation before infolding to form the neural keel; consists of a thickened pseudostratified epithelium. Kimmel et al, 1995.[TAO] (...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord that is located dorsal to the notochord (...).[well established][VHOG] @@ -43243,34 +43444,34 @@ For example, A and B may be gene products and binding of B by A positively regul neural plate https://upload.wikimedia.org/wikipedia/commons/8/8f/Neural_Crest.png - + - + - + - + GOTAX:0000352 - + Wikipedia - + Bgee:AN @@ -43301,6 +43502,14 @@ For example, A and B may be gene products and binding of B by A positively regul ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.28 http://bgee.unil.ch/ + + + + MESH:D054258 + + + https://github.com/biopragmatics/biomappings + @@ -43312,7 +43521,7 @@ For example, A and B may be gene products and binding of B by A positively regul lamina neuralis Wikipedia:Neural_plate - + @@ -43335,7 +43544,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube[GO]. Mesoderm lateral to the neural tube and notochord that is divided into cranial and post-cranial portions. The trunk portions further segment into somites.[AAO] Presently, Cephalochordata, Urochordata, and Vertebrata are placed as subphyla of the phylum Chordata, in which the overall organization of embryonic tissues (dorsal hollow nerve cord, ventral digestive tract, axial notochord, and bilateral paraxial mesoderm) is largely conserved. In contrast, the echinoderms and hemichordates are sister groups of the chordates and they lack the notochord and paraxial mesoderm. Thus, the basic mesodermal organization of vertebrates must have appeared first in the common ancestor of the chordates.[well established][VHOG] @@ -43364,7 +43573,7 @@ For example, A and B may be gene products and binding of B by A positively regul paraxial mesoderm http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + @@ -43377,7 +43586,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Bgee:AN @@ -43437,7 +43646,7 @@ For example, A and B may be gene products and binding of B by A positively regul mesoderma paraxiale Wikipedia:Paraxial_mesoderm - + @@ -43449,7 +43658,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -43493,7 +43702,7 @@ For example, A and B may be gene products and binding of B by A positively regul lateral plate mesoderm http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png - + @@ -43506,7 +43715,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + EHDAA2 VHOG @@ -43581,7 +43790,7 @@ For example, A and B may be gene products and binding of B by A positively regul mesoderma laminae lateralis Wikipedia:Lateral_plate_mesoderm - + @@ -43590,15 +43799,15 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + - + Bilateral groups of cells consisting of three rows: one row of endocardial precursors medially and two rows of myocardical precursors laterally. The two populations fuse at the midline to form the heart rudiment or cone. should probably be merged with heart rudiment. Bilateral groups of cells consisting of three rows: one row of endocardial precursors medially and two rows of myocardical precursors laterally. The two populations fuse at the midline between 21 and 26 somites to form the heart rudiment or cone. Stainier 2001.[TAO] @@ -43618,15 +43827,15 @@ For example, A and B may be gene products and binding of B by A positively regul heart primordium - + - + - + @@ -43639,19 +43848,19 @@ For example, A and B may be gene products and binding of B by A positively regul - + ZFA - + ZFA - + XAO @@ -43706,8 +43915,8 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + Ventral somitic compartment that is a precursor of the axial skeleton[XAO]. Sclerotomes eventually differentiate into the vertebrae and most of the skull. The caudal (posterior) half of one sclerotome fuses with the rostral (anterior) half of the adjacent one to form each vertebra. From their initial location within the somite, the sclerotome cells migrate medially towards the notochord. These cells meet the sclerotome cells from the other side to form the vertebral body. From this vertebral body, sclerotome cells move dorsally and surround the developing spinal cord, forming the vertebral arch[WP]. Skeletogenic portion of somites.[AAO] The vertebrate sclerotome has no equivalent in amphioxus and is a novelty linked with the evolution of the axial skeleton.[well established][VHOG] @@ -43735,11 +43944,11 @@ For example, A and B may be gene products and binding of B by A positively regul sclerotome http://upload.wikimedia.org/wikipedia/commons/9/96/Gray65.png - + - + @@ -43758,13 +43967,13 @@ For example, A and B may be gene products and binding of B by A positively regul - + VHOG:0000680 - + ZFA @@ -43804,7 +44013,9 @@ For example, A and B may be gene products and binding of B by A positively regul BTO:0006255 - https://orcid.org/0000-0003-4423-4370 + + + https://github.com/biopragmatics/biomappings @@ -43824,7 +44035,7 @@ For example, A and B may be gene products and binding of B by A positively regul sclerotomus Wikipedia:Sclerotome - + @@ -43964,7 +44175,7 @@ For example, A and B may be gene products and binding of B by A positively regul mesenchyma Wikipedia:Mesenchyme - + @@ -44070,7 +44281,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -44098,14 +44309,14 @@ For example, A and B may be gene products and binding of B by A positively regul Genes: The positional specification of the metanephrogenic mesenchyme is negatively regulated by Foxc1 and Foxc2. Next the permanent kidney forming metanephrogenic mesenchyme is specified by Hox11 genes. The competence to respond to ureteric bud inducers is regulated by WT1. GDNF secretion restricted to posterior region by Robo2 and Sprouty1. The receptors for GDNF are synthesized in the nephric ducts and later in ureteric buds [ISBN:9780878932504 "Developmental Biology"] metanephric mesenchyme - + - + ISBN:9780878932504 @@ -44821,7 +45032,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + The part of the coelom in the embryo between the somatopleuric and splanchnopleuric mesoderm; the principal body cavities of the trunk (thoracic, abdominal, and pelvic) arise from this embryonic part of the coelom. consider merging with coelom. TODO - add spatial relationships to halves of LPM. Note the OG places XAO and ZFA coelem terms here. editor note: TODO check ZFA, which appears to be a structure present in adults (...) I regard it unlikely that coeloms of all bilaterian animals are comparable and evolved very early. Considering all these questions, few convincing characters concerning the evolution of body cavities remain to be named. (...) A segmental coelom appears to have evolved at least two times, in Annelida and in Myomerata (Acrania and Craniota).[well established][VHOG] @@ -44837,14 +45048,14 @@ For example, A and B may be gene products and binding of B by A positively regul intraembryonic coelom - + - + Wikipedia @@ -44954,6 +45165,12 @@ For example, A and B may be gene products and binding of B by A positively regul GO:0060562 PMID:12526790 + + + + FBbt:00007474 + + @@ -45150,7 +45367,7 @@ For example, A and B may be gene products and binding of B by A positively regul tubulus renalis colligens Wikipedia:Collecting_duct_system - + @@ -45471,8 +45688,8 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + In mammals, the proximal tubule is a nephron tubule that connects Bowman's capsule to the loop of Henle. It has a brush border epithelial morphology[GO]. TODO - ensure definition works across species. @@ -45489,24 +45706,24 @@ For example, A and B may be gene products and binding of B by A positively regul proximal tubule - + - + - + GO - + GO @@ -45566,7 +45783,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + The intermediate tubule is a nephron tubule that lies between the proximal and distal tubules. TODO - check for applicability across species FMA:17718 @@ -45576,14 +45793,14 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0004136 intermediate tubule - + - + FMA @@ -45669,8 +45886,8 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + A specific region of the lateral mesoderm that will form the primary beating heart tube. In mammals the primary heart field gives rise to the left ventricle. this term denotes the primary heart field; GO:0003128 denotes the superclass of primary and secondary: specific region of the lateral mesoderm into the area which will form the primary beating heart tube[GO:0003138] XAO:0004185 @@ -45683,24 +45900,24 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0004140 primary heart field - + - + - + GO:0003128 - + https://orcid.org/0000-0003-3308-6245 @@ -45759,7 +45976,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + An epithelial tube that will give rise to the mature heart. the paired, longitudinal, endothelial-lined channels formed from the cardiogenic mesoderm in embryonic development; angiogenic cell clusters (aka angioblastic cords) located in a horse-shoe shape configuration in the cardiogenic plate coalesce to form the right and left endocardial heart tubes which then fuse in cephalo-caudal direction to form a single primitive heart tube. AAO:0010411 @@ -45779,14 +45996,14 @@ For example, A and B may be gene products and binding of B by A positively regul heart tube - + - + ZFA-modified @@ -46012,8 +46229,8 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + The comma-shaped body is the precursor structure to the S-shaped body that contributes to the morphogenesis of the nephron. EMAPA:27681 ZFA:0005588 @@ -46023,24 +46240,24 @@ For example, A and B may be gene products and binding of B by A positively regul comma-shaped body - + - + - + cjm - + ZFA @@ -46062,11 +46279,12 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + The S-shaped body is the successor of the comma-shaped body that contributes to the morphogenesis of the nephron. TODO EMAPA:27756 + VO:0010896 ZFA:0005589 SSB stage II nephron @@ -46075,24 +46293,24 @@ For example, A and B may be gene products and binding of B by A positively regul S-shaped body - + - + - + cjm - + GO @@ -46101,6 +46319,14 @@ For example, A and B may be gene products and binding of B by A positively regul The S-shaped body is the successor of the comma-shaped body that contributes to the morphogenesis of the nephron. GO:0072050 + + + + VO:0010896 + + + https://github.com/biopragmatics/biomappings + @@ -46237,7 +46463,7 @@ For example, A and B may be gene products and binding of B by A positively regul pyramides renales Wikipedia:Renal_pyramids - + @@ -46329,7 +46555,7 @@ For example, A and B may be gene products and binding of B by A positively regul stria externa medullae renalis FMA:76662 FMA:TA - + @@ -46512,7 +46738,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -46551,14 +46777,14 @@ For example, A and B may be gene products and binding of B by A positively regul glomerular capillary - + - + https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -46819,6 +47045,14 @@ For example, A and B may be gene products and binding of B by A positively regul VHOG includes a very broad grouping here based on http://www.ncbi.nlm.nih.gov/pubmed/9609826 VHOG + + + + MESH:D054240 + + + https://github.com/biopragmatics/biomappings + @@ -47141,6 +47375,7 @@ For example, A and B may be gene products and binding of B by A positively regul An endothelium that lines the blood vasculature. Other endothelia may line lymph vessels, the heart. + BTO:0000766 CALOHA:TS-2155 EMAPA:35176 @@ -47151,6 +47386,7 @@ For example, A and B may be gene products and binding of B by A positively regul ZFA:0005257 uberon UBERON:0004638 + blood vessel endothelium @@ -47188,7 +47424,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -47225,14 +47461,14 @@ For example, A and B may be gene products and binding of B by A positively regul renal afferent arteriole http://upload.wikimedia.org/wikipedia/commons/0/02/Gray1128.png - + - + Wikipedia @@ -47267,7 +47503,7 @@ For example, A and B may be gene products and binding of B by A positively regul arteriola glomerularis afferens renis FMA:77042 FMA:TA - + @@ -47280,7 +47516,7 @@ For example, A and B may be gene products and binding of B by A positively regul arteriola glomerularis afferens Wikipedia:Afferent_arterioles - + @@ -47420,14 +47656,14 @@ For example, A and B may be gene products and binding of B by A positively regul arteriae corticales radiatae Wikipedia:Interlobular_arteries - + arteriae interlobulares renis Wikipedia:Interlobular_arteries - + @@ -47520,6 +47756,12 @@ For example, A and B may be gene products and binding of B by A positively regul We explicitly merge the NCITA terms here NCIT + + + + FBbt:00005317 + + @@ -47593,7 +47835,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Organ consisting of skeletal tissue. Encompasses whole bones, fused bones, cartilaginious elements, teeth, dermal denticles. Organ entity that is typically involved in mechanical support and may have different skeletal tissue compositions at different stages.[VSAO] Organ entity that may have different tissue compositions at different stages and is typically involved in mechanical support.[TAO] @@ -47609,14 +47851,14 @@ For example, A and B may be gene products and binding of B by A positively regul skeletal element - + - + VSAO @@ -47661,7 +47903,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -47700,14 +47942,14 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0004770 articular system - + - + FMA @@ -48023,7 +48265,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -48046,14 +48288,14 @@ For example, A and B may be gene products and binding of B by A positively regul somatopleure http://upload.wikimedia.org/wikipedia/commons/2/28/Gray16.png - + - + EHDAA2 @@ -48110,7 +48352,7 @@ For example, A and B may be gene products and binding of B by A positively regul chorda nephrogenica Wikipedia:Nephrogenic_cord - + @@ -48119,9 +48361,9 @@ For example, A and B may be gene products and binding of B by A positively regul - - - + + + @@ -48142,34 +48384,34 @@ For example, A and B may be gene products and binding of B by A positively regul urogenital fold - + - + - + - + EHDAA2 - + Wikipedia - + EHDAA2 @@ -48293,6 +48535,12 @@ For example, A and B may be gene products and binding of B by A positively regul Anatomical structure that connects two or more adjacent skeletal elements or hardened body parts. http://orcid.org/0000-0002-6601-2165 + + + + FBbt:00005811 + + @@ -48345,6 +48593,12 @@ For example, A and B may be gene products and binding of B by A positively regul A proximal-distal subdivision of the digestive tract. http://orcid.org/0000-0002-6601-2165 + + + + FBbt:00100315 + + @@ -48672,28 +48926,28 @@ For example, A and B may be gene products and binding of B by A positively regul - - . + + Missing definition for term UBERON:0005095. Please replace it using linked reference. class added for consistency with GO - consider merging with kidney mesenchyme. uberon kidney anlage UBERON:0005095 kidney rudiment - + - + GO - . + Missing definition for term UBERON:0005095. Please replace it using linked reference. GO:0072003 @@ -48803,7 +49057,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + The connecting tubule is a tubular segment of the nephron; it connects the distal convoluted tubule to the collecting duct[GO]. BTO:0004539 @@ -48821,14 +49075,14 @@ For example, A and B may be gene products and binding of B by A positively regul renal connecting tubule http://upload.wikimedia.org/wikipedia/commons/0/02/Gray1128.png - + - + Wikipedia @@ -48855,7 +49109,7 @@ For example, A and B may be gene products and binding of B by A positively regul tubulus renalis arcuatus Wikipedia:Connecting_tubule - + @@ -49561,7 +49815,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Mesenchyme that is part of a developing trunk. EFO:0003485 EHDAA2:0002092 @@ -49577,14 +49831,14 @@ For example, A and B may be gene products and binding of B by A positively regul trunk mesenchyme - + - + EHDAA2 @@ -49675,6 +49929,12 @@ For example, A and B may be gene products and binding of B by A positively regul developing anatomical structure + + + + FBbt:00007006 + + @@ -49695,7 +49955,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Multi-tissue structure that arises from the heart rudiment and will become the heart tube. BTO:0006179 EHDAA2:0001512 @@ -49714,14 +49974,14 @@ For example, A and B may be gene products and binding of B by A positively regul primitive heart tube - + - + ZFA @@ -49734,7 +49994,9 @@ For example, A and B may be gene products and binding of B by A positively regul BTO:0006179 - https://orcid.org/0000-0003-4423-4370 + + + https://github.com/biopragmatics/biomappings @@ -49755,7 +50017,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -49784,7 +50046,7 @@ For example, A and B may be gene products and binding of B by A positively regul gonad primordium - + @@ -49797,7 +50059,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + ZFA @@ -49864,14 +50126,14 @@ For example, A and B may be gene products and binding of B by A positively regul - + - + A mesoderm that has the potential to develop into a pronephros. Portion of tissue that consists of the mesenchymal precursor to the pronephric kidney and that begins to separate from the intermediate mesoderm at NF stage 21 and epithelializes by NF stage 30.[AAO] AAO:0011090 @@ -49890,24 +50152,24 @@ For example, A and B may be gene products and binding of B by A positively regul the intermediate mesoderm of the chick embryo acquires its ability to form kidneys through its interactions with the paraxial mesoderm [ISBN:9780878932504 "Developmental Biology", PMID:10720431 "Signals from trunk paraxial mesoderm induce pronephros formation in chick intermediate mesoderm"]. These interactions induce the expression of TFs including Lim1, Pax2 and Pax6 that cause the intermediate mesoderm to form the kidney pronephric mesoderm - + - + - + ZFA - + Bgee:AN @@ -49963,7 +50225,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -49982,14 +50244,14 @@ For example, A and B may be gene products and binding of B by A positively regul glomerular tuft - + - + Wikipedia @@ -50220,7 +50482,7 @@ For example, A and B may be gene products and binding of B by A positively regul membrana basalis Wikipedia:Basement_membrane - + @@ -50246,7 +50508,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -50276,14 +50538,14 @@ For example, A and B may be gene products and binding of B by A positively regul glomerular basement membrane http://upload.wikimedia.org/wikipedia/commons/d/de/PhysiologieGlom%C3%A9rulaire.png - + - + true https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships @@ -50309,6 +50571,14 @@ For example, A and B may be gene products and binding of B by A positively regul GBM + + + + MESH:D050533 + + + https://github.com/biopragmatics/biomappings + @@ -50377,7 +50647,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + A delimited region of dense mesenchyme within looser mesenchyme. AEO:0000148 EHDAA2_RETIRED:0003148 @@ -50387,7 +50657,7 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0005856 developing mesenchymal condensation - + @@ -50406,7 +50676,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + AEO-modified-relation @@ -50499,7 +50769,7 @@ For example, A and B may be gene products and binding of B by A positively regul skeleton axiale Wikipedia:Axial_skeleton - + @@ -50514,7 +50784,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -50555,14 +50825,14 @@ For example, A and B may be gene products and binding of B by A positively regul cloacal membrane http://upload.wikimedia.org/wikipedia/commons/d/d2/Gray991.png - + - + Wikipedia @@ -50603,7 +50873,7 @@ For example, A and B may be gene products and binding of B by A positively regul membrana cloacalis Wikipedia:Cloacal_membrane - + @@ -50615,7 +50885,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + The notochordal plate is the dorsal part of the notochordal process when the ventral portion breaks down. It is continuous laterally with the endoderm that composes the roof of the primitive foregut and is in contact dorsally with the neural tube. The folding off of the notochordal plate gives rise to the notochord. TODO - check ordering; awaiting confirmation from JB The notochordal plate is the dorsal part of the notochordal process when the ventral portion breaks down. It is continuous laterally with the endoderm that composes the roof of the primitive foregut and is in contact dorsally with the neural tube. The folding off of the notochordal plate gives rise to the notochord. [Carson_JL, Dehart_DB, Developmental_Dynamics_(1994)_201:_260-278, Gesteland_K_and_Schoenwolf_GC, Inagaki_T, Morphogenesis_of_the_murine_node_and_notochordal_plate, The_prechordal_plate, Vrablic_T, see_Mueller_F_and_O'Rahilly_R, the_rostral_end_of_the_notochord_and_nearby_median_features_in_staged_human_embryos._Cells_Tissues_Organs_(2003)_173:_1-20_and_Sulik_K][VHOG] @@ -50630,7 +50900,7 @@ For example, A and B may be gene products and binding of B by A positively regul notochordal plate - + @@ -50643,7 +50913,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + EHDAA2 @@ -50680,7 +50950,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + A midline cellular cord formed from the migration of mesenchymal cells from the primitive knot. EHDAA2:0001279 EHDAA:224 @@ -50697,14 +50967,14 @@ For example, A and B may be gene products and binding of B by A positively regul The notochordal process grows cranially until it reaches the prechordal plate, the future site of the mouth. In this area the ectoderm is attached directly to the endoderm without intervening mesoderm. This area is known as the oropharyngeal membrane, and it will break down to become the mouth. At the other end of the primitive streak the ectoderm is also fused directly to the endoderm; this is known as the cloacal membrane (proctodeum), or primordial anus. notochordal process - + - + EHDAA2 @@ -51255,7 +51525,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + A region of nephron tubule that is part of a cortex of kidney. EMAPA:18976 MA:0002609 @@ -51265,14 +51535,14 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0006853 renal cortex tubule - + - + MA @@ -51329,6 +51599,12 @@ For example, A and B may be gene products and binding of B by A positively regul The distalmost portion of the digestive tract, derived from the hindgut, and terminating with the anus. http://orcid.org/0000-0002-6601-2165 + + + + FBbt:00005756 + + @@ -51757,7 +52033,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + A hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood or analogs[GO,modified]. note we reserve the subclass 'heart' from the vertebrate multi-chambered heart. 'The first heart-like organ is believed to have appeared 500my ago in an ancestral bilaterian'. Amniotes: four-chambered heart. Amphibians: two atria, one ventricle, pulmonary; fish: single atrium and ventricle; amphioxus: tubular, non-striated, closed, unidirectional; ascidians: tubular, striated, open, bidirectional; arthropods: tubular, open; C elegans: contractile pharynx; Cnideria: striated muscle cells associated with gastrodermis SPD:0000130 @@ -51772,14 +52048,14 @@ For example, A and B may be gene products and binding of B by A positively regul Gene notes: Bmp, Nkx, Gata primary circulatory organ - + - + GO uses blood circulation generically to include the haemolymphatic fluid of arthropods @@ -51869,7 +52145,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -51886,14 +52162,14 @@ For example, A and B may be gene products and binding of B by A positively regul presumptive segmental plate - + - + https://github.com/obophenotype/uberon/wiki/The-neural-crest EDHAA2 @@ -51992,7 +52268,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -52018,7 +52294,7 @@ For example, A and B may be gene products and binding of B by A positively regul presumptive paraxial mesoderm - + @@ -52034,7 +52310,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + https://github.com/obophenotype/uberon/issues/1277 @@ -52195,7 +52471,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Mesenchyme with little extracellular matrix. AEO:0000146 EHDAA2:0003146 @@ -52203,7 +52479,7 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0007524 dense mesenchyme tissue - + @@ -52216,7 +52492,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + AEO @@ -52424,6 +52700,12 @@ For example, A and B may be gene products and binding of B by A positively regul FBbt:00005426 http://flybase.org/reports/FBrf0178740.html + + + + FBbt:00005426 + + @@ -52431,7 +52713,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Anatomical system that consists of all blood and lymph vessels. consider merging with vasculature @@ -52450,14 +52732,14 @@ For example, A and B may be gene products and binding of B by A positively regul vascular system - + - + MA @@ -52617,7 +52899,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -52660,14 +52942,14 @@ For example, A and B may be gene products and binding of B by A positively regul pelvic girdle skeleton http://upload.wikimedia.org/wikipedia/commons/f/fe/Gray242.png - + - + PMID:21455939 @@ -52763,7 +53045,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + The functional tissue of the kidney, consisting of the nephrons. BTO:0003604 FMA:15574 @@ -52774,7 +53056,7 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0008987 renal parenchyma - + @@ -52787,7 +53069,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + FMA @@ -52857,7 +53139,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -52874,14 +53156,14 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0009142 entire embryonic mesenchyme - + - + EHDAA2 @@ -53000,7 +53282,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + EHDAA2:0002094 trunk and cervical paraxial mesenchyme uberon @@ -53008,14 +53290,14 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0009618 trunk paraxial mesoderm - + - + EHDAA2 @@ -53114,7 +53396,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + EFO:0003704 TAO:0005041 ZFA:0005041 @@ -53124,14 +53406,14 @@ For example, A and B may be gene products and binding of B by A positively regul anterior lateral plate mesoderm - + - + ZFA @@ -53228,7 +53510,7 @@ For example, A and B may be gene products and binding of B by A positively regul arteriae interlobares renis Wikipedia:Interlobar_arteries - + @@ -53277,7 +53559,7 @@ For example, A and B may be gene products and binding of B by A positively regul lobus FMA:45728 FMA:TA - + @@ -53369,7 +53651,7 @@ For example, A and B may be gene products and binding of B by A positively regul lobi renales Wikipedia:Renal_lobe - + @@ -53420,6 +53702,12 @@ For example, A and B may be gene products and binding of B by A positively regul An anatomical structure that has more than one cell as a part. CARO:0010000 + + + + FBbt:00100313 + + @@ -53460,7 +53748,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -53478,14 +53766,14 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0010227 future cardiac atrium - + - + ZFA @@ -53628,7 +53916,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -53642,7 +53930,7 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0010377 mesenchyme from somatopleure - + @@ -53655,7 +53943,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + EHDAA2 @@ -53671,7 +53959,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + A vessel of the microcirculature, lying between the arterioles and venules; includes capillaries (blood and lymphatic), metarterioles and arteriovenous anastomoses. MESH:D055806 TAO:0005251 @@ -53681,14 +53969,14 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0010523 microcirculatory vessel - + - + ZFA @@ -53721,7 +54009,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -53738,7 +54026,7 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0010532 primitive nephron - + @@ -53751,7 +54039,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + EHDAA2 @@ -53773,7 +54061,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -53784,7 +54072,7 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0010536 nephron progenitor - + @@ -53797,7 +54085,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + cjm @@ -54119,8 +54407,8 @@ For example, A and B may be gene products and binding of B by A positively regul - - + + Anatomical cluster consisting of the skeletal elements (i.e. bone elements, cartilage elements, cartilage condensations) that are part of an individual subdivision of the organism. Excludes joints. Anatomical cluster consisting of the skeletal elements that are part of the skeleton.[VSAO] FMA:23879 @@ -54133,11 +54421,11 @@ For example, A and B may be gene products and binding of B by A positively regul subdivision of skeleton - + - + @@ -54150,13 +54438,13 @@ For example, A and B may be gene products and binding of B by A positively regul - + UBERONREF:0000003 - + VSAO @@ -54227,7 +54515,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Subdivision of the skeletal system which consists of the postcranial axial skeleton plus associated joints. axial skeletal system FMA:302077 @@ -54237,7 +54525,7 @@ For example, A and B may be gene products and binding of B by A positively regul postcranial axial skeletal system http://purl.obolibrary.org/obo/uberon/docs/The-axial-skeleton - + @@ -54250,7 +54538,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + cjm @@ -54274,7 +54562,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -54287,7 +54575,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + Subdivision of urinary system which consists of the kidney and the ureters. FMA:45658 @@ -54300,24 +54588,24 @@ For example, A and B may be gene products and binding of B by A positively regul upper urinary tract - + - + - + FMA - + FMA-abduced-lr @@ -54343,12 +54631,14 @@ For example, A and B may be gene products and binding of B by A positively regul + FBbt:00007330 FMA:67509 SCTID:91690000 uberon UBERON:0011216 + organ system subdivision @@ -54364,6 +54654,12 @@ For example, A and B may be gene products and binding of B by A positively regul A subdivision of an anatomical system. http://orcid.org/0000-0002-6601-2165 + + + + FBbt:00007330 + + @@ -54639,7 +54935,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -54654,14 +54950,14 @@ For example, A and B may be gene products and binding of B by A positively regul We presume this is distinct from AAO:0001003, an external integumentary structure - check with amphibian anatomy ontology developers. AO notes: the text def states mesenchymal swelling, EHDAA2 splits into mesenchymal and epithelial parts embryonic cloacal fold - + - + EHDAA2 @@ -54684,20 +54980,20 @@ For example, A and B may be gene products and binding of B by A positively regul - + EHDAA2:0004588 uberon UBERON:0012361 internal anal region - + - + EHDAA2 @@ -54707,20 +55003,20 @@ For example, A and B may be gene products and binding of B by A positively regul - + EHDAA2:0004589 uberon UBERON:0012469 external anal region - + - + EHDAA2 @@ -54747,7 +55043,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -54767,14 +55063,14 @@ For example, A and B may be gene products and binding of B by A positively regul skeleton of pelvic complex - + - + FMA @@ -54826,7 +55122,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + The precursor of the urethra. In humans, the urethral groove is a temporary linear indentation on the underside (ventral side) of the male penis during embryonic development. It typically appears around 8 weeks of gestation and becomes closed into a normal male urethra by the 12th week SCTID:361531004 @@ -54838,14 +55134,14 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0013241 embryonic urethral groove - + - + Wikipedia @@ -54865,7 +55161,7 @@ For example, A and B may be gene products and binding of B by A positively regul sulcus urethralis primarius Wikipedia:Urethral_groove - + @@ -54985,7 +55281,6 @@ For example, A and B may be gene products and binding of B by A positively regul The region of the organism associated with the visceral organs. - Cardinal body part, which consists of a maximal set of diverse subclasses of organ and organ part spatially associated with the vertebral column and ribcage. Examples: There is only one body proper[FMA:231424]. AEO:0000103 BTO:0001489 @@ -54995,7 +55290,6 @@ For example, A and B may be gene products and binding of B by A positively regul body whole body UBERON:0013702 - body proper @@ -55073,7 +55367,9 @@ For example, A and B may be gene products and binding of B by A positively regul BTO:0006187 - https://orcid.org/0000-0003-4423-4370 + + + https://github.com/biopragmatics/biomappings @@ -55458,7 +55754,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + @@ -55481,7 +55777,7 @@ For example, A and B may be gene products and binding of B by A positively regul UBERON:0016887 entire extraembryonic component - + @@ -55494,7 +55790,7 @@ For example, A and B may be gene products and binding of B by A positively regul - + AEO @@ -55640,6 +55936,12 @@ For example, A and B may be gene products and binding of B by A positively regul Material anatomical entity consisting of multiple anatomical structures that are not connected to each other. CARO:0020000 + + + + FBbt:00007276 + + @@ -55915,23 +56217,25 @@ For example, A and B may be gene products and binding of B by A positively regul - + The upper tract of the renal system. The renal pelvis is the large cavity in the middle of each kidney. Urine drains from each kidney through a long tube called the ureter, into the bladder, where it is stored until it is passed from the body through the urethra. + NCIT:C54419 renal pelvis and ureter renal pelvis plus ureter uberon UBERON:0036295 + renal pelvis/ureter - + - + NCIT @@ -56009,7 +56313,9 @@ For example, A and B may be gene products and binding of B by A positively regul BTO:0006338 - https://orcid.org/0000-0003-4423-4370 + + + https://github.com/biopragmatics/biomappings @@ -56268,6 +56574,24 @@ For example, A and B may be gene products and binding of B by A positively regul /////////////////////////////////////////////////////////////////////////////////////// --> + + + + + + + + + + + + + + + + + + @@ -56298,6 +56622,16 @@ For example, A and B may be gene products and binding of B by A positively regul + + + + + + + + + + diff --git a/subsets/kidney_upper_slim.tsv b/subsets/kidney_upper_slim.tsv index 0fcb14222..134b85af5 100644 --- a/subsets/kidney_upper_slim.tsv +++ 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+_:Be350484aX2D0263X2D4acdX2Da142X2D4091eb1e8e26genid927 +_:Be350484aX2D0263X2D4acdX2Da142X2D4091eb1e8e26genid934 +_:Be350484aX2D0263X2D4acdX2Da142X2D4091eb1e8e26genid941 +_:Be350484aX2D0263X2D4acdX2Da142X2D4091eb1e8e26genid947 +_:Be350484aX2D0263X2D4acdX2Da142X2D4091eb1e8e26genid953 +_:Be350484aX2D0263X2D4acdX2Da142X2D4091eb1e8e26genid960 +_:Be350484aX2D0263X2D4acdX2Da142X2D4091eb1e8e26genid967 +_:Be350484aX2D0263X2D4acdX2Da142X2D4091eb1e8e26genid973 +_:Be350484aX2D0263X2D4acdX2Da142X2D4091eb1e8e26genid980 +_:Be350484aX2D0263X2D4acdX2Da142X2D4091eb1e8e26genid986 +_:Be350484aX2D0263X2D4acdX2Da142X2D4091eb1e8e26genid993 "continuant" "occurrent" "independent continuant" @@ -481,7 +478,6 @@ _:B6571aa82X2D487eX2D4480X2Db6d1X2D930b425859f2genid996 "acidophilic cytoplasm" "basophilic cytoplasm" "polychromatophilic cytoplasm" - "increased nucleus size" "epithelial cell of nephron" "epithelial cell of glomerular capsule" "kidney collecting duct epithelial cell" @@ -856,14 +852,9 @@ _:B6571aa82X2D487eX2D4480X2Db6d1X2D930b425859f2genid996 "quality" "morphology" "shape" - "qualitative" - "deviation (from_normal)" - "size" "structure" "branched" "circular" - "normal" - "increased size" "elliptic" "physical quality" "physical object quality" @@ -898,8 +889,6 @@ _:B6571aa82X2D487eX2D4480X2Db6d1X2D930b425859f2genid996 "subcylindrical" "3-D shape" "tubular" - "increased quality" - "increased object quality" "fiber shaped" "superelliptic" "acidophilic" @@ -908,6 +897,7 @@ _:B6571aa82X2D487eX2D4480X2Db6d1X2D930b425859f2genid996 "disconnected" "polymeric" "distensibility" + "high nuclear/cytoplasmic ratio" "anatomical structure quality" "anatomical histological quality" "polychromatophilic"