diff --git a/.github/workflows/test.yml b/.github/workflows/test.yml
index 6f5acb1c8c..5efac69e52 100644
--- a/.github/workflows/test.yml
+++ b/.github/workflows/test.yml
@@ -6,7 +6,7 @@ on:
     - 'release/*'
   pull_request:
 env:
-  CORE_REPO_SHA: 3b236f5309c36d089c0d9dc6dc6c985bb1668776
+  CORE_REPO_SHA: c4cdffd0c8bd47b2e5c4f4a823722ca514f10db3
 
 jobs:
   build:
diff --git a/CHANGELOG.md b/CHANGELOG.md
index 6acedf12e3..8edd0ac74b 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -43,6 +43,8 @@ and this project adheres to [Semantic Versioning](https://semver.org/spec/v2.0.0
 - `opentelemetry-instrumentation-botocore` now supports
   context propagation for lambda invoke via Payload embedded headers.
   ([#458](https://github.com/open-telemetry/opentelemetry-python-contrib/pull/458))
+- Added support for CreateKey functionality.
+  ([#502](https://github.com/open-telemetry/opentelemetry-python-contrib/pull/502))
 
 ## [0.21b0](https://github.com/open-telemetry/opentelemetry-python/releases/tag/v1.2.0-0.21b0) - 2021-05-11
 
diff --git a/exporter/opentelemetry-exporter-datadog/src/opentelemetry/exporter/datadog/spanprocessor.py b/exporter/opentelemetry-exporter-datadog/src/opentelemetry/exporter/datadog/spanprocessor.py
index 1eb7aed740..d6581dd5cc 100644
--- a/exporter/opentelemetry-exporter-datadog/src/opentelemetry/exporter/datadog/spanprocessor.py
+++ b/exporter/opentelemetry-exporter-datadog/src/opentelemetry/exporter/datadog/spanprocessor.py
@@ -18,6 +18,7 @@
 import typing
 
 from opentelemetry.context import Context, attach, detach, set_value
+from opentelemetry.instrumentation.utils import _SUPPRESS_INSTRUMENTATION_KEY
 from opentelemetry.sdk.trace import Span, SpanProcessor
 from opentelemetry.sdk.trace.export import SpanExporter
 from opentelemetry.trace import INVALID_TRACE_ID
@@ -163,7 +164,7 @@ def export(self) -> None:
                         del self.traces_spans_ended_count[trace_id]
 
         if len(export_trace_ids) > 0:
-            token = attach(set_value("suppress_instrumentation", True))
+            token = attach(set_value(_SUPPRESS_INSTRUMENTATION_KEY, True))
 
             for trace_id in export_trace_ids:
                 with self.traces_lock:
diff --git a/instrumentation/opentelemetry-instrumentation-aiohttp-client/src/opentelemetry/instrumentation/aiohttp_client/__init__.py b/instrumentation/opentelemetry-instrumentation-aiohttp-client/src/opentelemetry/instrumentation/aiohttp_client/__init__.py
index b9441ca108..d4000584bb 100644
--- a/instrumentation/opentelemetry-instrumentation-aiohttp-client/src/opentelemetry/instrumentation/aiohttp_client/__init__.py
+++ b/instrumentation/opentelemetry-instrumentation-aiohttp-client/src/opentelemetry/instrumentation/aiohttp_client/__init__.py
@@ -75,6 +75,7 @@ def strip_query_params(url: yarl.URL) -> str:
 from opentelemetry.instrumentation.aiohttp_client.version import __version__
 from opentelemetry.instrumentation.instrumentor import BaseInstrumentor
 from opentelemetry.instrumentation.utils import (
+    _SUPPRESS_INSTRUMENTATION_KEY,
     http_status_to_status_code,
     unwrap,
 )
@@ -155,7 +156,7 @@ async def on_request_start(
         trace_config_ctx: types.SimpleNamespace,
         params: aiohttp.TraceRequestStartParams,
     ):
-        if context_api.get_value("suppress_instrumentation"):
+        if context_api.get_value(_SUPPRESS_INSTRUMENTATION_KEY):
             trace_config_ctx.span = None
             return
 
@@ -248,7 +249,7 @@ def _instrument(
     """
     # pylint:disable=unused-argument
     def instrumented_init(wrapped, instance, args, kwargs):
-        if context_api.get_value("suppress_instrumentation"):
+        if context_api.get_value(_SUPPRESS_INSTRUMENTATION_KEY):
             return wrapped(*args, **kwargs)
 
         trace_configs = list(kwargs.get("trace_configs") or ())
diff --git a/instrumentation/opentelemetry-instrumentation-aiohttp-client/tests/test_aiohttp_client_integration.py b/instrumentation/opentelemetry-instrumentation-aiohttp-client/tests/test_aiohttp_client_integration.py
index a9f82202d8..7acb52f38f 100644
--- a/instrumentation/opentelemetry-instrumentation-aiohttp-client/tests/test_aiohttp_client_integration.py
+++ b/instrumentation/opentelemetry-instrumentation-aiohttp-client/tests/test_aiohttp_client_integration.py
@@ -30,6 +30,7 @@
 from opentelemetry.instrumentation.aiohttp_client import (
     AioHttpClientInstrumentor,
 )
+from opentelemetry.instrumentation.utils import _SUPPRESS_INSTRUMENTATION_KEY
 from opentelemetry.semconv.trace import SpanAttributes
 from opentelemetry.test.test_base import TestBase
 from opentelemetry.trace import StatusCode
@@ -448,7 +449,7 @@ async def uninstrument_request(server: aiohttp.test_utils.TestServer):
 
     def test_suppress_instrumentation(self):
         token = context.attach(
-            context.set_value("suppress_instrumentation", True)
+            context.set_value(_SUPPRESS_INSTRUMENTATION_KEY, True)
         )
         try:
             run_with_test_server(
@@ -462,7 +463,7 @@ def test_suppress_instrumentation(self):
     async def suppressed_request(server: aiohttp.test_utils.TestServer):
         async with aiohttp.test_utils.TestClient(server) as client:
             token = context.attach(
-                context.set_value("suppress_instrumentation", True)
+                context.set_value(_SUPPRESS_INSTRUMENTATION_KEY, True)
             )
             await client.get(TestAioHttpClientInstrumentor.URL)
             context.detach(token)
diff --git a/instrumentation/opentelemetry-instrumentation-botocore/src/opentelemetry/instrumentation/botocore/__init__.py b/instrumentation/opentelemetry-instrumentation-botocore/src/opentelemetry/instrumentation/botocore/__init__.py
index 457d312463..0439490c5c 100644
--- a/instrumentation/opentelemetry-instrumentation-botocore/src/opentelemetry/instrumentation/botocore/__init__.py
+++ b/instrumentation/opentelemetry-instrumentation-botocore/src/opentelemetry/instrumentation/botocore/__init__.py
@@ -58,7 +58,10 @@
 from opentelemetry.instrumentation.botocore.package import _instruments
 from opentelemetry.instrumentation.botocore.version import __version__
 from opentelemetry.instrumentation.instrumentor import BaseInstrumentor
-from opentelemetry.instrumentation.utils import unwrap
+from opentelemetry.instrumentation.utils import (
+    _SUPPRESS_INSTRUMENTATION_KEY,
+    unwrap,
+)
 from opentelemetry.propagate import inject
 from opentelemetry.semconv.trace import SpanAttributes
 from opentelemetry.trace import SpanKind, get_tracer
@@ -128,7 +131,7 @@ def _patch_lambda_invoke(api_params):
 
     # pylint: disable=too-many-branches
     def _patched_api_call(self, original_func, instance, args, kwargs):
-        if context_api.get_value("suppress_instrumentation"):
+        if context_api.get_value(_SUPPRESS_INSTRUMENTATION_KEY):
             return original_func(*args, **kwargs)
 
         # pylint: disable=protected-access
diff --git a/instrumentation/opentelemetry-instrumentation-botocore/tests/test_botocore_instrumentation.py b/instrumentation/opentelemetry-instrumentation-botocore/tests/test_botocore_instrumentation.py
index 58a065cca8..e77a255d13 100644
--- a/instrumentation/opentelemetry-instrumentation-botocore/tests/test_botocore_instrumentation.py
+++ b/instrumentation/opentelemetry-instrumentation-botocore/tests/test_botocore_instrumentation.py
@@ -34,6 +34,7 @@
 from opentelemetry import trace as trace_api
 from opentelemetry.context import attach, detach, set_value
 from opentelemetry.instrumentation.botocore import BotocoreInstrumentor
+from opentelemetry.instrumentation.utils import _SUPPRESS_INSTRUMENTATION_KEY
 from opentelemetry.propagate import get_global_textmap, set_global_textmap
 from opentelemetry.semconv.trace import SpanAttributes
 from opentelemetry.test.mock_textmap import MockTextMapPropagator
@@ -509,7 +510,7 @@ def test_suppress_instrumentation_xray_client(self):
         xray_client = self.session.create_client(
             "xray", region_name="us-east-1"
         )
-        token = attach(set_value("suppress_instrumentation", True))
+        token = attach(set_value(_SUPPRESS_INSTRUMENTATION_KEY, True))
         xray_client.put_trace_segments(TraceSegmentDocuments=["str1"])
         xray_client.put_trace_segments(TraceSegmentDocuments=["str2"])
         detach(token)
diff --git a/instrumentation/opentelemetry-instrumentation-requests/src/opentelemetry/instrumentation/requests/__init__.py b/instrumentation/opentelemetry-instrumentation-requests/src/opentelemetry/instrumentation/requests/__init__.py
index 451dca22a8..d0e1473b19 100644
--- a/instrumentation/opentelemetry-instrumentation-requests/src/opentelemetry/instrumentation/requests/__init__.py
+++ b/instrumentation/opentelemetry-instrumentation-requests/src/opentelemetry/instrumentation/requests/__init__.py
@@ -45,7 +45,10 @@
 from opentelemetry.instrumentation.instrumentor import BaseInstrumentor
 from opentelemetry.instrumentation.requests.package import _instruments
 from opentelemetry.instrumentation.requests.version import __version__
-from opentelemetry.instrumentation.utils import http_status_to_status_code
+from opentelemetry.instrumentation.utils import (
+    _SUPPRESS_INSTRUMENTATION_KEY,
+    http_status_to_status_code,
+)
 from opentelemetry.propagate import inject
 from opentelemetry.semconv.trace import SpanAttributes
 from opentelemetry.trace import SpanKind, get_tracer
@@ -54,7 +57,9 @@
 
 # A key to a context variable to avoid creating duplicate spans when instrumenting
 # both, Session.request and Session.send, since Session.request calls into Session.send
-_SUPPRESS_HTTP_INSTRUMENTATION_KEY = "suppress_http_instrumentation"
+_SUPPRESS_HTTP_INSTRUMENTATION_KEY = context.create_key(
+    "suppress_http_instrumentation"
+)
 
 
 # pylint: disable=unused-argument
@@ -111,9 +116,9 @@ def call_wrapped():
     def _instrumented_requests_call(
         method: str, url: str, call_wrapped, get_or_create_headers
     ):
-        if context.get_value("suppress_instrumentation") or context.get_value(
-            _SUPPRESS_HTTP_INSTRUMENTATION_KEY
-        ):
+        if context.get_value(
+            _SUPPRESS_INSTRUMENTATION_KEY
+        ) or context.get_value(_SUPPRESS_HTTP_INSTRUMENTATION_KEY):
             return call_wrapped()
 
         # See
diff --git a/instrumentation/opentelemetry-instrumentation-requests/tests/test_requests_integration.py b/instrumentation/opentelemetry-instrumentation-requests/tests/test_requests_integration.py
index 95006d0602..e00bd3bd4f 100644
--- a/instrumentation/opentelemetry-instrumentation-requests/tests/test_requests_integration.py
+++ b/instrumentation/opentelemetry-instrumentation-requests/tests/test_requests_integration.py
@@ -21,6 +21,7 @@
 import opentelemetry.instrumentation.requests
 from opentelemetry import context, trace
 from opentelemetry.instrumentation.requests import RequestsInstrumentor
+from opentelemetry.instrumentation.utils import _SUPPRESS_INSTRUMENTATION_KEY
 from opentelemetry.propagate import get_global_textmap, set_global_textmap
 from opentelemetry.sdk import resources
 from opentelemetry.semconv.trace import SpanAttributes
@@ -165,7 +166,7 @@ def test_uninstrument_session(self):
 
     def test_suppress_instrumentation(self):
         token = context.attach(
-            context.set_value("suppress_instrumentation", True)
+            context.set_value(_SUPPRESS_INSTRUMENTATION_KEY, True)
         )
         try:
             result = self.perform_request(self.URL)
diff --git a/instrumentation/opentelemetry-instrumentation-urllib/src/opentelemetry/instrumentation/urllib/__init__.py b/instrumentation/opentelemetry-instrumentation-urllib/src/opentelemetry/instrumentation/urllib/__init__.py
index 1081a67d13..3a5f50908e 100644
--- a/instrumentation/opentelemetry-instrumentation-urllib/src/opentelemetry/instrumentation/urllib/__init__.py
+++ b/instrumentation/opentelemetry-instrumentation-urllib/src/opentelemetry/instrumentation/urllib/__init__.py
@@ -48,7 +48,10 @@
 from opentelemetry.instrumentation.instrumentor import BaseInstrumentor
 from opentelemetry.instrumentation.urllib.package import _instruments
 from opentelemetry.instrumentation.urllib.version import __version__
-from opentelemetry.instrumentation.utils import http_status_to_status_code
+from opentelemetry.instrumentation.utils import (
+    _SUPPRESS_INSTRUMENTATION_KEY,
+    http_status_to_status_code,
+)
 from opentelemetry.propagate import inject
 from opentelemetry.semconv.trace import SpanAttributes
 from opentelemetry.trace import SpanKind, get_tracer
@@ -56,7 +59,10 @@
 from opentelemetry.util.http import remove_url_credentials
 
 # A key to a context variable to avoid creating duplicate spans when instrumenting
-_SUPPRESS_HTTP_INSTRUMENTATION_KEY = "suppress_http_instrumentation"
+# both, Session.request and Session.send, since Session.request calls into Session.send
+_SUPPRESS_HTTP_INSTRUMENTATION_KEY = context.create_key(
+    "suppress_http_instrumentation"
+)
 
 
 class URLLibInstrumentor(BaseInstrumentor):
@@ -129,9 +135,9 @@ def call_wrapped():
     def _instrumented_open_call(
         _, request, call_wrapped, get_or_create_headers
     ):  # pylint: disable=too-many-locals
-        if context.get_value("suppress_instrumentation") or context.get_value(
-            _SUPPRESS_HTTP_INSTRUMENTATION_KEY
-        ):
+        if context.get_value(
+            _SUPPRESS_INSTRUMENTATION_KEY
+        ) or context.get_value(_SUPPRESS_HTTP_INSTRUMENTATION_KEY):
             return call_wrapped()
 
         method = request.get_method().upper()
diff --git a/instrumentation/opentelemetry-instrumentation-urllib/tests/test_urllib_integration.py b/instrumentation/opentelemetry-instrumentation-urllib/tests/test_urllib_integration.py
index d35ceb4c9e..9681c09686 100644
--- a/instrumentation/opentelemetry-instrumentation-urllib/tests/test_urllib_integration.py
+++ b/instrumentation/opentelemetry-instrumentation-urllib/tests/test_urllib_integration.py
@@ -28,6 +28,7 @@
 from opentelemetry.instrumentation.urllib import (  # pylint: disable=no-name-in-module,import-error
     URLLibInstrumentor,
 )
+from opentelemetry.instrumentation.utils import _SUPPRESS_INSTRUMENTATION_KEY
 from opentelemetry.propagate import get_global_textmap, set_global_textmap
 from opentelemetry.sdk import resources
 from opentelemetry.semconv.trace import SpanAttributes
@@ -198,7 +199,7 @@ def test_uninstrument_session(self):
 
     def test_suppress_instrumentation(self):
         token = context.attach(
-            context.set_value("suppress_instrumentation", True)
+            context.set_value(_SUPPRESS_INSTRUMENTATION_KEY, True)
         )
         try:
             result = self.perform_request(self.URL)
diff --git a/instrumentation/opentelemetry-instrumentation-urllib3/src/opentelemetry/instrumentation/urllib3/__init__.py b/instrumentation/opentelemetry-instrumentation-urllib3/src/opentelemetry/instrumentation/urllib3/__init__.py
index 3e6cb1008a..0d2d7ed17b 100644
--- a/instrumentation/opentelemetry-instrumentation-urllib3/src/opentelemetry/instrumentation/urllib3/__init__.py
+++ b/instrumentation/opentelemetry-instrumentation-urllib3/src/opentelemetry/instrumentation/urllib3/__init__.py
@@ -56,6 +56,7 @@ def span_name_callback(method: str, url: str, headers):
 from opentelemetry.instrumentation.urllib3.package import _instruments
 from opentelemetry.instrumentation.urllib3.version import __version__
 from opentelemetry.instrumentation.utils import (
+    _SUPPRESS_INSTRUMENTATION_KEY,
     http_status_to_status_code,
     unwrap,
 )
@@ -64,7 +65,11 @@ def span_name_callback(method: str, url: str, headers):
 from opentelemetry.trace import Span, SpanKind, get_tracer
 from opentelemetry.trace.status import Status
 
-_SUPPRESS_HTTP_INSTRUMENTATION_KEY = "suppress_http_instrumentation"
+# A key to a context variable to avoid creating duplicate spans when instrumenting
+# both, Session.request and Session.send, since Session.request calls into Session.send
+_SUPPRESS_HTTP_INSTRUMENTATION_KEY = context.create_key(
+    "suppress_http_instrumentation"
+)
 
 _UrlFilterT = typing.Optional[typing.Callable[[str], str]]
 _SpanNameT = typing.Optional[
@@ -214,7 +219,7 @@ def _apply_response(span: Span, response: urllib3.response.HTTPResponse):
 
 def _is_instrumentation_suppressed() -> bool:
     return bool(
-        context.get_value("suppress_instrumentation")
+        context.get_value(_SUPPRESS_INSTRUMENTATION_KEY)
         or context.get_value(_SUPPRESS_HTTP_INSTRUMENTATION_KEY)
     )
 
diff --git a/instrumentation/opentelemetry-instrumentation-urllib3/tests/test_urllib3_integration.py b/instrumentation/opentelemetry-instrumentation-urllib3/tests/test_urllib3_integration.py
index 658044887b..670e7917d8 100644
--- a/instrumentation/opentelemetry-instrumentation-urllib3/tests/test_urllib3_integration.py
+++ b/instrumentation/opentelemetry-instrumentation-urllib3/tests/test_urllib3_integration.py
@@ -20,7 +20,11 @@
 import urllib3.exceptions
 
 from opentelemetry import context, trace
-from opentelemetry.instrumentation.urllib3 import URLLib3Instrumentor
+from opentelemetry.instrumentation.urllib3 import (
+    _SUPPRESS_HTTP_INSTRUMENTATION_KEY,
+    URLLib3Instrumentor,
+)
+from opentelemetry.instrumentation.utils import _SUPPRESS_INSTRUMENTATION_KEY
 from opentelemetry.propagate import get_global_textmap, set_global_textmap
 from opentelemetry.semconv.trace import SpanAttributes
 from opentelemetry.test.mock_textmap import MockTextMapPropagator
@@ -165,8 +169,8 @@ def test_uninstrument(self):
 
     def test_suppress_instrumntation(self):
         suppression_keys = (
-            "suppress_instrumentation",
-            "suppress_http_instrumentation",
+            _SUPPRESS_HTTP_INSTRUMENTATION_KEY,
+            _SUPPRESS_INSTRUMENTATION_KEY,
         )
         for key in suppression_keys:
             self.memory_exporter.clear()
diff --git a/opentelemetry-instrumentation/src/opentelemetry/instrumentation/utils.py b/opentelemetry-instrumentation/src/opentelemetry/instrumentation/utils.py
index dec070570f..16f75aae6c 100644
--- a/opentelemetry-instrumentation/src/opentelemetry/instrumentation/utils.py
+++ b/opentelemetry-instrumentation/src/opentelemetry/instrumentation/utils.py
@@ -16,8 +16,14 @@
 
 from wrapt import ObjectProxy
 
+from opentelemetry.context import create_key
 from opentelemetry.trace import StatusCode
 
+# FIXME This is a temporary location for the suppress instrumentation key.
+# Once the decision around how to suppress instrumentation is made in the
+# spec, this key should be moved accordingly.
+_SUPPRESS_INSTRUMENTATION_KEY = create_key("suppress_instrumentation")
+
 
 def extract_attributes_from_object(
     obj: any, attributes: Sequence[str], existing: Dict[str, str] = None
diff --git a/tox.ini b/tox.ini
index e2b97cc61f..ee63f91552 100644
--- a/tox.ini
+++ b/tox.ini
@@ -228,11 +228,10 @@ commands_pre =
 ; cases but it saves a lot of boilerplate in this file.
   test: pip install {toxinidir}/opentelemetry-python-core/opentelemetry-api[test]
   test: pip install {toxinidir}/opentelemetry-python-core/opentelemetry-semantic-conventions[test]
+  test: pip install {toxinidir}/opentelemetry-instrumentation[test]
   test: pip install {toxinidir}/opentelemetry-python-core/opentelemetry-sdk[test]
   test: pip install {toxinidir}/opentelemetry-python-core/tests/util[test]
 
-  test: pip install {toxinidir}/opentelemetry-instrumentation[test]
-
   celery: pip install {toxinidir}/instrumentation/opentelemetry-instrumentation-celery[test]
 
   grpc: pip install {toxinidir}/instrumentation/opentelemetry-instrumentation-grpc[test]
@@ -325,8 +324,8 @@ deps =
 commands_pre =
   python -m pip install {toxinidir}/opentelemetry-python-core/opentelemetry-api
   python -m pip install {toxinidir}/opentelemetry-python-core/opentelemetry-semantic-conventions
-  python -m pip install {toxinidir}/opentelemetry-python-core/opentelemetry-sdk
   python -m pip install {toxinidir}/opentelemetry-instrumentation
+  python -m pip install {toxinidir}/opentelemetry-python-core/opentelemetry-sdk
   python -m pip install {toxinidir}/util/opentelemetry-util-http
 
 changedir = docs
@@ -352,9 +351,9 @@ commands_pre =
   sudo apt-get install libsnappy-dev
   python -m pip install {toxinidir}/opentelemetry-python-core/opentelemetry-api
   python -m pip install {toxinidir}/opentelemetry-python-core/opentelemetry-semantic-conventions
+  python -m pip install -e {toxinidir}/opentelemetry-instrumentation[test]
   python -m pip install {toxinidir}/opentelemetry-python-core/opentelemetry-sdk
   python -m pip install {toxinidir}/opentelemetry-python-core/tests/util
-  python -m pip install -e {toxinidir}/opentelemetry-instrumentation[test]
   python -m pip install -e {toxinidir}/util/opentelemetry-util-http[test]
   python -m pip install -e {toxinidir}/instrumentation/opentelemetry-instrumentation-wsgi[test]
   python -m pip install -e {toxinidir}/instrumentation/opentelemetry-instrumentation-dbapi[test]
@@ -420,9 +419,9 @@ changedir =
 commands_pre =
   pip install -e {toxinidir}/opentelemetry-python-core/opentelemetry-api \
               -e {toxinidir}/opentelemetry-python-core/opentelemetry-semantic-conventions \
+              -e {toxinidir}/opentelemetry-instrumentation \
               -e {toxinidir}/opentelemetry-python-core/opentelemetry-sdk \
               -e {toxinidir}/opentelemetry-python-core/tests/util \
-              -e {toxinidir}/opentelemetry-instrumentation \
               -e {toxinidir}/instrumentation/opentelemetry-instrumentation-asyncpg \
               -e {toxinidir}/instrumentation/opentelemetry-instrumentation-celery \
               -e {toxinidir}/instrumentation/opentelemetry-instrumentation-dbapi \