Under-vaccination and severe COVID-19 outcomes: meta-analysis of national cohort studies of over 64 million people in England, Northern Ireland, Scotland and Wales
Receiving fewer than the recommended number of SARS-CoV-2 vaccines doses (under-vaccination) may be associated with poorer COVID-19 outcomes. We sought to determine the factors associated with under-vaccination, and the risk of hospitalisation or death after COVID-19 in people who were under-vaccinated in each of the UK nations, and across the UK population.
The BHF Data Science Centre supported access to the English data only for this project.
HDR UK COALESCE Consortium. Undervaccination and severe COVID-19 outcomes: meta-analysis of national cohort studies in England, Northern Ireland, Scotland, and Wales. Lancet. 2024;403(10426):554-566. https://doi.org/10.1016/S0140-6736(23)02467-4
- View the analysis code used in NHS England's SDE for England
- View the phenotyping algorithms and codelists used in NHS England's SDE for England
- View the analysis code and phenotypes used in the Safe Haven
- View the analysis code and phenotypes used in the SAIL Databank
This is a sub-project of project CCU051 approved by the CVD-COVID-UK / COVID-IMPACT Approvals & Oversight Board (sub-project: CCU051_01) and forms part of the wider COALESCE study.
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