Estimate average coverage and create Nonpareil curves for metagenomic datasets.
Stand-alone or Online querying.
If you use Nonpareil, please cite:
Rodriguez-R et al. 2018. Nonpareil 3: Fast estimation of metagenomic coverage and sequence diversity. mSystems 3(3): e00039-18. DOI: 10.1128/mSystems.00039-18.
Rodriguez-R & Konstantinidis. 2014. Nonpareil: a redundancy-based approach to assess the level of coverage in metagenomic datasets. Bioinformatics 30 (5): 629-635. DOI: 10.1093/bioinformatics/btt584.
For an extended discussion on coverage in metagenomic data, see also:
Rodriguez-R & Konstantinidis. 2014. Estimating coverage in metagenomic data sets and why it matters. The ISME Journal 8: 2349–2351. DOI: 10.1038/ismej.2014.76.