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[NTR] TAC3-positive medium spiny neurons #2301

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AvolaAmg opened this issue Mar 1, 2024 · 1 comment · Fixed by #2304
Closed

[NTR] TAC3-positive medium spiny neurons #2301

AvolaAmg opened this issue Mar 1, 2024 · 1 comment · Fixed by #2304

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@AvolaAmg
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AvolaAmg commented Mar 1, 2024

Please check that the term does not already exist by using the ontology search tool OLS:
https://www.ebi.ac.uk/ols4/ontologies/cl

Preferred term label
TAC3-positive medium spiny neuron

synonyms
D1Sh TAC3 archetype
database_cross_reference
PMID:34727523

synonym
TAC3-positive MSN
database_cross_reference
PMID:34727523

synonym
TAC3-positive D1Sh-MSN
database_cross_reference
PMID:34727523

Definition
A nucleus accumbens shell and olfactory tubercle D1 medium spiny neuron that expresses TAC3. This medium spiny neuron has an enriched expression of the genes MPPED1, HPCAL1, MEIS3.

database_cross_reference
PMID:34727523

Parent cell type term (check the hierarchy here https://www.ebi.ac.uk/ols4/ontologies/cl)
nucleus accumbes shell and olfactory tubercle D1 medium spiny neuron

Anatomical structure where the cell type is found (check Uberon for anatomical structures: https://www.ebi.ac.uk/ols4/ontologies/uberon)
striatum

Additional notes or concerns
In Rhesus Macaque, TC3-positive medium spiny neuron has its soma in a cluster in the medial shell region of the nucleus accumbes and co-expresses the DRD1 receptor.

@AvolaAmg AvolaAmg self-assigned this Mar 1, 2024
@AvolaAmg
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AvolaAmg commented Mar 1, 2024

@aleixpuigb @dosumis

@AvolaAmg AvolaAmg added the BICAN label Mar 1, 2024
AvolaAmg added a commit that referenced this issue Mar 4, 2024
New Term Request TAC3-positive medium spiny neurons
AvolaAmg added a commit that referenced this issue Mar 25, 2024
* Fixes #2301

New Term Request TAC3-positive medium spiny neurons

* Update cl-edit.owl

* Update cl-edit.owl

* Update cl-edit.owl

* Update cl-edit.owl

* New Term Request TAC3-positive medium spiny neurons

* Update cl-edit.owl
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